Category: 7. Science

  • Liquid metal used in novel circuit board scan self-heal and work after taking heavy damage

    Liquid metal used in novel circuit board scan self-heal and work after taking heavy damage

    A new type of self-healing and reconfigurable circuit board can withstand heavy damage and still work effectively, scientists say. It can even be completely recycled once it reaches the end of its life.

    The new breakthrough is owed to a material called a vitrimer, a special polymer capable of remaining rigid and durable at normal temperatures but malleable and reshapable at higher temperatures. The scientists outlined their findings in a new study published 1 June in the journal Advanced Materials.

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  • New yeast model sheds light on proteasome and mitochondrial interaction

    New yeast model sheds light on proteasome and mitochondrial interaction

    A study by the Center for Redox Processes in Biomedicine (Redoxoma) led by Marilene Demasi from the Butantan Institute (São Paulo, Brazil) presents a valuable new experimental model for investigating the interaction between the proteasome and mitochondrial function. In eukaryotic cells, the proteasome is a protein complex responsible for eliminating damaged and nonfunctional proteins, thereby helping to maintain cellular balance and proper functioning.

    In recent years, studies have revealed that the proteasome and mitochondria are more closely connected than previously thought. The proteasome plays a role in the quality control of proteins destined for the mitochondria, while mitochondrial metabolism affects the efficiency with which proteins marked for destruction are degraded.

    Redoxoma, a Research, Innovation and Dissemination Center (RIDC) of FAPESP based at the University of São Paulo’s Institute of Chemistry (IQ-USP) conducted research focusing on the effects of proteasome dysfunction in the C76S mutant strain of the yeast Saccharomyces cerevisiae. The study revealed that deficiency in this system leads to increased mitochondrial oxidative stress. This was evidenced by increased hydrogen peroxide (H2O2) release and a lower peroxiredoxin 1 (Prx1) concentration. Prx1 is a crucial enzyme in the removal of peroxides. In mammals, mitochondrial Prx3 is equivalent to Prx1 in yeast.

    The most important thing about this work is that we’ve a yeast strain that can serve as a model for investigating proteasome deficiency in relation to mitochondrial metabolism, a model that didn’t yet exist in the literature.”


    Marilene Demasi, Butantan Institute

    The study was published in an article in the journal Archives of Biochemistry and Biophysics.

    Next steps

    The researchers are now working to understand why Prx1 levels decrease in cells with compromised proteasomes. “We don’t yet know if there was a decrease in Prx1 gene expression, which is possible, since the proteasome also plays a role in gene transcription regulation, or if the protein oxidizes more. It may hyperoxidize and, as a result, be degraded more. Perhaps the excess peroxide is promoting its continuous degradation,” says the researcher at the Butantan Institute.

    To answer these questions, the group plans to conduct comparative transcriptome and proteomic analyses of the wild and mutant strains cultivated under respiratory conditions. The goal is to establish this strain as a model for studying the role of the ubiquitin-proteasome system in cell metabolism.

    Source:

    São Paulo Research Foundation (FAPESP)

    Journal reference:

    Avellaneda Penatti, N. M., et al. (2025). Decreased levels of Prx1 are associated with proteasome impairment and mitochondrial dysfunction in the yeast Saccharomyces cerevisiae. Archives of Biochemistry and Biophysics. doi.org/10.1016/j.abb.2025.110406.

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  • JWST unlocks 10-billion-year mystery of how galaxies shape themselves

    JWST unlocks 10-billion-year mystery of how galaxies shape themselves

    Many galaxies, including our own Milky Way, are characterized by a flat, extended, rotating stellar disk. These disk galaxies commonly contain two main parts: a thin disk and a thick disk. The thin disk contains younger, metal-rich stars, while the thick disk contains older, metal-poor stars. These distinct components hold fossil records that help astronomers understand how galaxies form stars, build up elements like oxygen and carbon, essential for life, and evolve into their present shapes.

    Until now, thin and thick disks have only been identified in the Milky Way and nearby galaxies. It has been impossible with previous telescopes to distinguish the thin edge of a distant galaxy when viewed from the side.

    That changed with the launching of the James Webb Space Telescope (JWST) in 2021, which is currently the largest telescope in space.

    An international team of researchers has examined 111 JWST images of distant edge-on galaxies, ones where the alignments enabled the researchers to observe the galaxies’ vertical disk structures.

    Takafumi Tsukui (formerly of the Australian National University and now based at Tohoku University), who led the research team, says that observing distant galaxies is like using a time machine, allowing us to see how galaxies have built their disks over cosmic history.

    “Thanks to the JWST’s sharp vision, we were able to identify thin and thick disks in galaxies beyond our local universe, some going as far back as 10 billion years ago.”

    The study revealed a consistent trend: in the earlier universe, more galaxies appear to have had a single thick disk, while in later epochs, more galaxies showed a two-layered structure with an additional thin disk component. This suggests that galaxies first formed a thick disk, followed by the formation of a thin disk within it. In more massive galaxies, this thin disk appears to have formed earlier.

    The study estimated the thin disk formation time for Milky Way-sized galaxies to be around 8 billion years ago. This figure aligns with formation timelines for the Milky Way itself, where stellar ages can be measured.

    To understand the revealed sequential formation from thick to thin disks and the corresponding formation timelines, the team not only examined the stellar structure but also the motion of gas, direct ingredients of stars obtained from the Atacama Large Millimeter/submillimeter Array (ALMA) and ground-based surveys in the literature. These observations supported a coherent formation scenario:

    • In the early universe, galactic disks are rich in gas and highly turbulent
    • Intense star formation in the turbulent disks gives rise to thick stellar disks
    • As stellar disks develop, they help stabilize the gas disks and reduce the turbulence
    • As the disk calms, a thin stellar disk forms inside the pre-developed thick stellar disks
    • Whereas larger galaxies can efficiently convert gas into stars, forming thin disks earlier

    Tsukui emphasizes that the images provided by JWST help answer one of the biggest questions in astronomy: was our galaxy’s formation typical or unique? “The JWST images provided a window into galaxies that resemble the Milky Way’s early state, bringing us valuable insights from galaxies far away.”

    The team hopes that their study will help bridge studies of nearby galaxies with far away ones and refine our understanding of disk formation. The study was published in the journal Monthly Notices of the Royal Astronomical Society on June 26, 2025.

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  • Planets may start forming before stars even finish growing

    Planets may start forming before stars even finish growing

    Signs of planet formation may appear earlier than expected around still-forming baby stars, according to new results of higher resolution images produced using new improved techniques to reanalyze radio astronomy archive data. These newly discovered signs of planet formation will provide a better understanding of when it begins around a young star, thereby elucidating the process that leads to planet formation, including habitable planets like Earth.

    Planets form in disks composed of low-temperature molecular gas and dust, known as protoplanetary disks, found around protostars. Protostars are stars still in the process of forming. The nascent planets are too small to observe directly, but the gravity from a planet can create detectable patterns like rings or spirals in a protoplanetary disk. However, it is difficult to know when these patterns first appeared due to the limited number of protoplanetary disks that are close enough to Earth to be observed in high resolution.

    A research team led by Ayumu Shoshi of Kyushu University and the Academia Sinica Institute of Astronomy and Astrophysics (ASIAA) used improved data processing techniques to search for previously overlooked signs of planet formation in archive data from the ALMA (Atacama Large Millimeter/submillimeter Array) radio telescope. The team reanalyzed data for 78 disks in the Ophiuchus star-forming region, located 460 light-years away in the direction of the constellation Ophiuchus. More than half of the images produced in this study achieved a resolution over three times better than that of previous images.

    The new high-resolution images show ring or spiral patterns in 27 of the disks. Of these, 15 were identified for the first time in this study. Combining this new sample with pervious work for a different star-forming region, the team found that the characteristic disk substructures emerge in disks larger than 30 au (astronomical units, 1 au = 149,597,870,700 m, the distance between the Earth and the Sun) around stars in the early stage of star formation, just a few hundred thousand years after a star was born. This suggests that planets begin to form at a much earlier stage than previously believed, when the disk still possesses abundant gas and dust. In other words, planets grow together with their very young host stars.

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  • Country’s space endeavors part of a shared human story

    Country’s space endeavors part of a shared human story

    The Chang’e-6 probe was launched from China on May 3, 2024. On June 25, 2024, its returner landed in North China, bringing back 1,935.3 grams of samples from the far side of the moon. [Xinhua]

    Once upon a time, the tale of Chang’e flying to the moon existed only in Chinese folklore. But today, that ancient myth has been given a new, modern twist with actual moon samples making their way not to the palace of the moon goddess, but to the headquarters of the United Nations in Vienna.

    On June 25, during the 68th session of the UN Committee on the Peaceful Uses of Outer Space, China organized an exhibition featuring lunar samples collected from both the near and far sides of the moon to celebrate 20 years of its lunar exploration program. The exhibition not only showcases China’s remarkable technical achievements, but also offers a window into the country’s vision of inclusive, peaceful and cooperative outer space exploration.

    The lunar samples, collected by the Chang’e-5 and Chang’e-6 missions respectively, represent landmarks in space science. Chang’e-5’s successful mission in 2020 made China the third country to retrieve materials from the moon after the United States and the Soviet Union. Chang’e-6 went even further, bringing back the first samples from the moon’s far side in 2024, marking another remarkable achievement for China.

    But China’s space program is not just about national pride or technical triumphs. The underlying message of the exhibition is a clear one: China’s space exploration is open to the world.

    The journey of Chang’e lunar exploration projects is no longer a solitary leap but a shared path. Over the past two decades, whether through bilateral agreements, joint missions, data-sharing or talent exchanges, China has made cooperation an important part of its space ambitions. The Chang’e-6 mission, for example, carried scientific payloads from France, Italy, Pakistan and the European Space Agency.

    China has agreed to share samples with other countries, because they belong not only to China, but also to the world, representing a shared treasure for all humanity. This approach reflects China’s principle of enhancing international cooperation in space on the basis of equality and mutual benefit, peaceful utilization and inclusive development. In a world where geopolitical tensions sometimes spill into the space domain, China’s emphasis on multilateralism and peaceful cooperation sends a timely and constructive signal.

    China’s space exploration achievements extend far beyond lunar missions. It made history with its Tianwen-1 mission to Mars, launched in July 2020 as China’s inaugural independent interplanetary endeavor. This groundbreaking mission, for the first time ever, successfully deployed an orbiter, lander and rover on the Red Planet in a single launch.

    China also operates two cutting-edge solar observation satellites in orbit. These sophisticated spacecraft have delivered significant breakthroughs, providing scientists with unprecedented insights into the behavior and characteristics of the sun.

    In fact, China has gone a step further by proposing the establishment of an open and inclusive platform for deep-space exploration, inviting countries, developed and developing alike, to participate in upcoming missions. For example, China has signed cooperation agreements with 17 countries and international organizations on the International Lunar Research Station construction, offering various levels and forms of collaboration opportunities. The first batch of experimental projects selected through China’s collaboration with the United Nations Office for Outer Space Affairs are being conducted aboard the Chinese space station.

    And just like the legend of Chang’e, what once felt distant and mythical is becoming part of a shared human story.

     

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