Category: 7. Science

  • The Merlin Bird ID App Is Better Than Meditation, and It’s Not Just for Birders

    The Merlin Bird ID App Is Better Than Meditation, and It’s Not Just for Birders

    I’ve done everything I can think of to improve my mindfulness. I’ve tried countless meditation apps and breathing exercises to stay in the present, and I’m always working on improving my mental health. 

    What helps me stay grounded has nothing to do with any of that. It’s an app for identifying birds. 

    Cornell Lab of Ornithology’s Merlin Bird ID launched in 2014 to help people identify the birds they see and hear. Thanks to eBird, the world’s largest database of bird sounds and photos based on 800 million global sightings, the app allows you to record a bird, answer a series of questions or upload a photo to name your winged friend. Or you can simply use the app to explore the different birds in your area, no matter where you are in the world, and even if you’re offline. 

    The homepage of the Merlin Bird ID app.

    The app’s homepage, with three avenues for identification.

    Anna Gragert/CNET

    One of my favorite features of Merlin Bird ID is that you can use it to keep track of your bird sightings and, like an IRL Pokemon GO, “collect ’em all.”

    The first time I used the app, I sat out on my balcony, clicked the green “Sound” button and watched as the app identified the birds chirping and singing in all directions. You can see the different sound frequencies as they appear on a real-time spectrogram, a visual representation of the audio world. The next time I checked the clock, I was shocked to see that an hour had passed. Then, I dug out my binoculars and let even more time fly.

    A spectrogram identifying Anna's Hummingbirds and Black Phoebes on the Merlin Bird ID app.

    What a spectrogram on the app looks like.

    Anna Gragert/CNET

    As any Merlin Bird IDer knows, there is no thrill quite like pressing the “This is my bird” button for the first time, and it never gets old. From there, you can record your location. The app, in turn, will save your report to improve its performance. 

    Before long, I had different bird sounds memorized. In the morning, I would wake to the sound of a California Towhee’s alarm-like and frankly, yes, annoying cheeping from a tree outside my window right as the sun started to rise. On walks around my neighborhood, I’d auditorially part the sound of cars and distant construction to hear the melody of House Finches mixed with staccato chirps of Lesser Goldfinches and the droning coos from a pair of Mourning Doves religiously stationed on electrical wires. It was the song that had been the soundtrack of my world, but I hadn’t noticed until now. 

    By sight, I’d recognize Red-Whiskered Bulbuls with their black crests and fire engine cheeks, a blush color waiting to be replicated in powder form. Black Phoebes made themselves known with their fluffy soot-black heads, statue stillness and ivory bellies. At the hummingbird feeder on my balcony, there is a never-ending line of customers with iridescent throats in sunset colors: Anna’s Hummingbirds (my favorite, as you might guess), Allen’s and even the uncommon Rufous, who spend all day fighting over sugar water when not watching the feeder from their magnolia tree perches. 

    A hummingbird at a feeder covered in rain with bright pink plants in the background.

    A customer at our feeder. I think they’re an Allen’s Hummingbird.

    Anna Gragert/CNET

    What’s most thrilling is when the Merlin Bird app hears a bird that you can’t see, making it feel as though it’s your mission to treasure hunt your way to it. This is often a lesson in patience, as it may take you several tries to find the songbird you seek. Recently, while sitting in a new-to-me park, the app told me a Mountain Chickadee was nearby and I spent the next 45 minutes trying to spot it with my binoculars. It ended up on a branch directly above my head, and when I got up to leave, it flew down right by my face as if in on the joke that it was there the whole time. 

    I’ve yet to find the Red-Winged Blackbird who always seems to be just out of reach, no matter where I am in my city, but I console myself with the seemingly all-knowing flock of Common Ravens (also unjustly called an “unkindness”) evermore on my street and the surprising number of noises they can produce. 

    The Explore Birds section on the Merlin Bird ID app showing a Red-Winged Blackbird, Great Horned Owl and others..

    Birds I haven’t spotted … yet.

    Anna Gragert/CNET

    I also often listen back to the comforting hoo-hoos of a Great Horned Owl singing a 9:30 p.m. lullaby right before the start of spring. I like time-travelling to these moments, though I have come across some retrospectively hilarious conversations I unintentionally recorded in between birdsong. With that being said, Merlin Bird ID does save your audio recordings but only on your device in the app. To share the recordings with eBird, you have to manually export and upload them. 

    I now seek out unexplored wooded spaces to meet new feathered friends, an excuse for forest bathing, which has led me to see the shade of blue unique to a Ruddy Duck’s bill. After a rainstorm, I’ve come across a group of Acorn Woodpeckers with impressive red mohawks excitedly pecking wet, softened wood while calling to each other. Like a conversation between punk besties over dinner. My area is known for its large flocks of Amazon parrots (and their persistent screeches), whom I’ve now had the pleasure of seeing up close as they use their light yellow bills to climb trees and collect their berries. And once, just once, I caught the backside of a Yellow Warbler in a nearby watershed park. 

    The Acorn Woodpecker photo and description on the Merlin Bird ID app.

    The Acorn Woodpecker

    Anna Gragert/CNET

    Because of this app, I’ve spent more time listening to the world around me and less time in my own head, bobbing between the past and future. I’ve found myself surrounded by and in conversation with nature more than ever before. It may be the closest thing we have to magic here on Earth. Now, perhaps that is the key to grounding yourself: Getting your butt on the ground and taking the time to listen to those who are singing around you. 


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  • Testing the Nature of 3I/ATLAS by Its Non-Gravitational Acceleration | by Avi Loeb | Aug, 2025

    Testing the Nature of 3I/ATLAS by Its Non-Gravitational Acceleration | by Avi Loeb | Aug, 2025

    Press enter or click to view image in full size

    (Image credit: Max Barry/Nation States)

    A simple way to distinguish a spacecraft from a rock is through its large non-gravitational acceleration. A natural icy rock like a comet is propelled by its mass loss. That mass loss can be observed through the cometary plume of gas and dust that surrounds the comet’s nucleus. By measuring the rate of mass loss and the characteristic ejection speed of gas and dust, one can calculate the rate of momentum change per unit time, or the non-gravitational force exerted on the nucleus. Since the evaporation occurs on the dayside of the rock which is warmed up by the virtue of it facing the Sun, this force pushes the comet’s nucleus away from the Sun. At a large enough distance, typically a few times the Earth-Sun separation, the surface of the nucleus is not warmed enough by sunlight to release volatile ices and dust and the cometary activity diminishes.

    A technological object, on the other hand, could operate an engine and maneuver independently of the Sun. It can be propelled towards the Sun or any planet of interest and exhibit a non-gravitational acceleration of arbitrary magnitude or direction. Observing non-gravitational maneuvers could shift the ranking of an interstellar object on the “Loeb scale”, from `0’ — the default value for a natural comet to `10’ — a definitely artificial object.

    Given this perspective, it is of great interest to measure the acceleration of the new interstellar object 3I/ATLAS along its path through the Solar System and check whether it shows any deviation from the expected trajectory, as dictated by gravity alone. If 3I/ATLAS will not continue along its expected path after its closest approach to the Sun on October 29, 2025, then the stock market might crash from worries about an alien tech visitation.

    If 3I/ATLAS is a natural comet, what is its expected non-gravitational acceleration?

    The recent imaging of 3I/ATLAS by the Hubble Space Telescope shows a glow ahead of the object but no bright tail of gas and dust behind it — as often observed for comets (see related paper here). In addition, spectroscopic measurements show no evidence for molecular or atomic gas accompanying this glow (see related papers here, here and here, as well as the discussion about water ice here). A natural interpretation of these anomalies is that 3I/ATLAS is a dust-rich comet that releases little gas, but mostly large dust particles which are not pushed back by Solar radiation pressure or the Solar wind because of their small surface-to-mass ratio. In this case, we can calculate the expected non-gravitational acceleration of this comet from the observed plume of dust leading it.

    A detailed analysis of the observed glow ahead of 3I/ATLAS (see related paper here) suggests a mass loss rate of up to 60 kilograms per second for dust particles of 100 micron size (where a micron is a millionth of a meter) and an ejection speed of ~2 meters per second in the direction of the Sun. The estimated mass loss rate drops to 6 kilograms per second and an ejection speed of 20 meters per second for 1-micron particles. Since the non-gravitational force exerted on 3I/ATLAS equals the mass loss rate times the ejection speed, its value is the same in both cases and does not depend on the assumed size of the ejected dust particles.

    The brightness distribution in the glow preceding 3I/ATLAS was also used to set limits on the diameter of its nucleus, inferred to be in the range of 0.32–5.6 kilometers. This implies that the nucleus mass is in the range of 30 billion to 200 trillion kilograms. Applying the resulting non-gravitational force to this mass leads to a non-gravitational acceleration in the range of 3×10^{-14} to 2×10^{-10} AU per day squared, where AU stands for Astronomical Unit which is defined as the Earth-Sun separation. This non-gravitational acceleration range is equivalent to values between 6×10^{-11} and 4×10^{-7} centimeters per second squared, in the direction away from the Sun.

    For comparison, the first interstellar object 1I/`Oumuamua exhibited on October 25, 2017 a non-gravitational acceleration of 1.4×10^{-7} AU per day squared, equivalent to 2.7×10^{-4} centimeters per second squared (see related data here). This is larger than the expected non-gravitational acceleration of 3I/ATLAS by a huge factor, ranging between a thousand and 10 million. If 1I/`Oumuamua was a familiar comet, it had to lose about a tenth of its mass during its passage close to the Sun. But despite its large non-gravitational acceleration, 1I/`Oumuamua did not display any cometary evaporation (see observational data here), making its large non-gravitational acceleration a major anomaly concerning its nature (as argued in my related paper here).

    If 3I/ATLAS is a natural comet, its outgassing may intensify as it gets closer to the Sun. A measurement of the expected non-gravitational from its cometary activity would confirm its natural origin. A paper that I wrote with my student, Sriram Elango, before the discovery of 3I/ATLAS, showed that localization data from the Webb telescope in combination with terrestrial telescopes can pinpoint the trajectory of an interstellar object to unprecedented precision using parallax, since the Webb telescope is located 1.5 million kilometers away from Earth at the L2 Lagrange point. A major deviation of the measured non-gravitational acceleration from the expected range for a comet, would suggest that 3I/ATLAS might be propelled technologically.

    For now, we cannot assess with any confidence whether 3I/ATLAS is a natural dust-rich comet with no gaseous tail on an extremely rare trajectory, or perhaps a technological object on a path that was designed to align with the ecliptic plane of the planets around the Sun. All we know is that 3I/ATLAS exhibits a rare (0.2% probability) alignment of its retrograde path with the ecliptic plane to within 5 degrees, and its arrival time along this path is perfectly suited for a close encounter with Mars, Venus and Jupiter (with a 0.0005% probability, as discussed here). These coincidences would allow a mothership to release mini-probes that will reach planets as they move into the mini-probes’ orbits, taking advantage of the mothership’s retrograde motion. Since 3I/ATLAS will hide behind the Sun at its perihelion on October 29, 2025, we will not be able to observe whether it releases any mini-probes into Earth’s orbit.

    Exquisite measurements of the non-gravitational acceleration of 3I/ATLAS would provide an important clue about its nature. The verdict will not be decided by debates on social media, but rather by accurate measurements of instruments. This is the same as the video assisted referee (VAR) protocol used by FIFA to decide whether a goal was scored under controversial circumstances. FIFA rules by viewing data recorded by cameras, rather than by asking soccer players or the goalkeeper for their opinions. We all know that the Earth moved around the Sun for 4.54 billion years before the Vatican placed Galileo Galilei in house arrest for suggesting that. Whether 3I/ATLAS is natural or technological in origin has nothing to do with popular opinions on Earth.

    ABOUT THE AUTHOR

    Press enter or click to view image in full size

    (Image Credit: Chris Michel, National Academy of Sciences, 2023)

    Avi Loeb is the head of the Galileo Project, founding director of Harvard University’s — Black Hole Initiative, director of the Institute for Theory and Computation at the Harvard-Smithsonian Center for Astrophysics, and the former chair of the astronomy department at Harvard University (2011–2020). He is a former member of the President’s Council of Advisors on Science and Technology and a former chair of the Board on Physics and Astronomy of the National Academies. He is the bestselling author of “Extraterrestrial: The First Sign of Intelligent Life Beyond Earth” and a co-author of the textbook “Life in the Cosmos”, both published in 2021. The paperback edition of his new book, titled “Interstellar”, was published in August 2024.

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  • August full moon 2025 captivates skywatchers worldwide as Sturgeon Moon lights up the sky (photos)

    August full moon 2025 captivates skywatchers worldwide as Sturgeon Moon lights up the sky (photos)

    August’s full moon, known as the ‘Sturgeon Moon’ made a splash when it leapt above the southern horizon on Aug. 9 earlier this week, illuminating the summer sky mere days before the peak of the Perseid meteor shower.

    The Sturgeon Moon gets its name from the large lake fish that were once abundant around this time of year and which served as an important source of food for several Native American tribes. It’s also sometimes known as the ‘Red Moon’, on account of the ruddy hue it has been known to adopt in the summer haze, while the Anishinaabe people of the Great Lakes knew it as the ‘Ricing Moon’ and used it as a sign that it was time to bring in the harvest.


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  • See Saturn and the moon in a stunning close encounter on Aug. 11

    See Saturn and the moon in a stunning close encounter on Aug. 11

    Monday evening (Aug. 11) offers a perfect chance to identify what many consider the most beautiful object in the night sky: the ringed planet Saturn. Helping guide the way, will be another familiar celestial companion, the moon, shining in its waning gibbous phase.

    As I’ve pointed out over the years here at Space.com, to the naked eye, Saturn does not exactly scream for attention. It lacks the dazzling, eye-popping brilliance of Venus or Jupiter and it does not have the fiery orange-yellow color of Mars.


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  • James Webb telescope captures one of the deepest-ever views of the universe, improving on iconic Hubble image — Space photo of the week

    James Webb telescope captures one of the deepest-ever views of the universe, improving on iconic Hubble image — Space photo of the week

    Quick facts

    What it is: The Hubble Ultra Deep Field, revisited by the James Webb Space Telescope

    Where it is: Close to the Big Dipper in the night sky

    When it was shared: Aug. 1, 2025

    The James Webb Space Telescope‘s (JWST) latest extragalactic survey has revealed fainter and more distant objects than ever before, some dating back to the earliest periods of the universe. But it stands on the shoulders of a giant: When NASA published the Hubble Ultra Deep Field image in 2004, it stunned the world of astronomy. A composite of 800 images from exposures totaling 11 days, the deep image of an otherwise unremarkable part of the night sky revealed nearly 10,000 galaxies, many among the most distant known.

    Now, JWST has observed that same patch of sky with different eyes — and found 2,500 more objects. Crucially, they’re even more distant.

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  • NASA’s Hubble Telescope discovers rare ‘Zombie Star’ formed from a violent cosmic collision

    NASA’s Hubble Telescope discovers rare ‘Zombie Star’ formed from a violent cosmic collision

    Hydrogen-rich white dwarfs can appear deceptively ordinary in optical light, making their true origin difficult to determine. Ultraviolet data is crucial because it can detect the faint carbon signatures that betray a merger history. Without Hubble’s ultraviolet capability, WD 0525+526 would likely have been classified as a typical white dwarf, masking the fact that it is the product of a violent stellar collision.
    WD 0525+526, zombie star, ultra-massive white dwarf, Hubble Space Telescope, NASA, James Webb Space Telescope, star merger, binary star evolution, stellar collision, ultraviolet astronomy, carbon signature, hydrogen-rich atmosphere, semi-convection, University of Warwick, Nature Astronomy, stellar remnant, neutron star, gamma-ray burst, post-merger evolution, massive white dwarf, stellar death

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  • See The ‘Planet Parade’ On Monday As Venus And Jupiter Twin

    See The ‘Planet Parade’ On Monday As Venus And Jupiter Twin

    Topline

    Early risers this month can see a “planet parade” building in the eastern sky before sunrise featuring Saturn, Jupiter, Venus and Mercury. Best seen about an hour before sunrise, on Monday, Aug. 11, Saturn will be visible in the south, with bright planets Jupiter and Venus in the east. Mercury may also be glimpsed below Venus and Jupiter as sunrise nears, but the “Swift Planet” will be easier to see later this week. Uranus and Neptune will also be in the sky — making a six-planet parade — but neither is visible to the naked eye.

    Key Facts

    About an hour before sunrise, Venus and Jupiter — the two brightest planets in the solar system — will appear to be very close to each other, while Saturn will be easily visible in the southern sky.

    The highlight of this week’s “planet parade” will come on Tuesday, Aug. 12, when the two planets will be just 0.9 degrees apart. Jupiter will be on the left, slightly higher in the sky than Venus.

    Mercury will join the “planet parade” on or around Tuesday, Aug. 12, according to Sky & Telescope, becoming visible just above the eastern horizon about 45 minutes before sunrise. It will be farthest from the sun — so highest in the sky — on Aug. 19 and remain visible until around Aug. 26.

    Saturn is currently brightening as it nears its annual bright “opposition” on Sept. 21, when Earth will be between Saturn and the sun.

    The next “planet parade” isn’t until October 2028, when five planets will be visible together before sunrise.

    Watch For Early ‘shooting Stars’

    If you’re outside while it’s dark — or you return after dark later in the day — keep your eyes peeled for “shooting stars” from the Perseid meteor shower. It peaks overnight on Tuesday, Aug. 12 through Wednesday, Aug. 13, when 50-75 “shooting stars” are typically visible each hour, with activity high on the nights either side. Bright moonlight will restrict visibility this year, but the Perseids are known for their occasional very bright fireballs.

    What’s Next In The ‘planet Parade’

    This “planet parade” will become more visible and easier to see as the days pass during August. After this week’s Venus-Jupiter conjunction, Mercury will become easier to see as it rises higher. Next week, as Mercury reaches its highest point in the morning sky, a waning crescent moon will move through the planets, creating a beautiful scene. Here are the key dates:

    • Monday, Aug. 18: A 26% crescent moon will glow near Venus and Jupiter.
    • Tuesday, Aug. 19: Mercury will be at its highest in the morning sky as the moon wanes to 16%-lit and forms a curve with Venus and Jupiter.
    • Wednesday, Aug. 20: A 9%-lit crescent moon will appear very close to Venus, with Mercury below and Jupiter above:
    • Thursday, Aug. 21: a slender 4%-lit waning crescent moon will be beneath Jupiter and Venus, close to Mercury.

    What’s Next In The Night Sky

    The “planet parade” will draw to a close around Aug. 26 as Mercury disappears from view, leaving Saturn and Jupiter to gradually brighten as Venus begins to fade. However, Venus has one last act — before sunrise on Aug. 31, it will pass across the Beehive Cluster, one of the closest open clusters of stars to the solar system, which should be a fabulous sight through binoculars.

    Further Reading

    ForbesA Six-Planet Parade Is Coming — When To See ItForbesPerseid Meteor Shower Begins Next Week — When To Get The Best ViewForbesDon’t Miss This Week’s Dazzling Venus-Jupiter Encounter

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  • NASA’s Voyager 1 discovers a fiery hot zone in space — but there’s no fire! What’s going on?

    NASA’s Voyager 1 discovers a fiery hot zone in space — but there’s no fire! What’s going on?

    In a time when space missions often involve the latest technology and huge budgets, NASA’s Voyager 1 stands out as a true classic. Launched way back in 1977– when cassette tapes were still popular– this old spacecraft is still making news. Recently, Voyager 1 discovered a very hot and energetic area just beyond the edge of our solar system that scientists didn’t expect.This new zone, which researchers are calling a “firewall,” could change what we thought about the border between our solar system and the vast space beyond. A hot zone without fire: What Voyager detectedVoyager 1 has entered a region where particles are so energetic that their temperatures measure between 30,000 and 50,000 degrees Celsius, as per an Economic Times report. But don’t worry– this doesn’t mean there are flames or fire. The particles are spread out so thinly that they don’t act like heat does on Earth.

    Representative image

    The spacecraft is safe and working just fine. What’s really interesting is that scientists didn’t expect to find this kind of hot zone. It’s making them rethink what they know about how space behaves just beyond the edge of our solar system.Redefining where the solar system endsFor many years, scientists have debated where the solar system really ends. As per a report by Economic Times, some say it’s the faraway Oort Cloud, but NASA defines the edge as the heliopause– the spot where the Sun’s solar wind slows down and can no longer push back against particles coming from outside our solar system.Voyager 1 crossed this boundary back in 2012. But now, finding this unexpected hot zone just beyond it shows that the boundary between our solar system and interstellar space isn’t as clear or simple as we thought. This new discovery suggests that the outer edge of the Sun’s influence is more complex than we once believed.

    Representative image

    Magnetic fields defy previous assumptionsAlong with the heat surprise, Voyager 1 has been sending back unexpected information about magnetic fields. Scientists thought the magnetic conditions outside the heliopause would be very different from those inside. But Voyager’s data shows there’s some magnetic connection between the two areas, as per the ET report.This finding has sparked new questions about whether the Sun’s magnetic influence reaches farther than we thought, or if interstellar space is more linked to our solar system than we previously believed.Images: Canva (for representative purposes only)


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  • Planning for the Ultimate Space Mission

    Planning for the Ultimate Space Mission

    As a child, I remember gazing up at the stars and dreaming of spacecraft journeying to distant worlds, those classic images of rockets blasting off toward unknown frontiers filled my imagination. But a mission to a black hole? That seemed beyond even the wildest science fiction. These stellar corpses were the stuff of theoretical physics books back then, mysterious objects so extreme that they devoured light itself. The idea that we might actually send something there, even a device smaller than a paperclip, makes you realise we’re living in an era where the impossible is slowly becoming possible.

    Images of the Apollo 11 Saturn V rocket launch with astronauts Neil A. Armstrong, Michael Collins and Edwin E. Aldrin inspired me and many other children to dream of travelling among the stars (Credit : NASA)

    Here’s the idea; astrophysicist Cosimo Bambi from Fudan University has outlined an ambitious plan to send microscopic spacecraft to the nearest black hole. These “nanocrafts” would weigh just grams and consist of a microchip and light sail, propelled by powerful Earth based lasers to reach one third the speed of light. The mission would be a marathon, not a sprint. It would take about 70 years for the craft to reach a black hole 20 to 25 light years away, with another 20 years for the data to travel back to Earth, making the total mission duration around 80 to 100 years.

    Black holes represent the universe’s most extreme conditions, where our understanding of physics is pushed to its limits. This mission could answer fundamental questions: Does a black hole truly have an event horizon beyond which nothing can escape? Do the rules of physics change near black holes? Does Einstein’s theory of general relativity hold under these extreme conditions? These aren’t just academic questions. Understanding how physics works in the most extreme environments could revolutionize our knowledge of space, time, and the universe itself.

    Image of the black hole at the centre of the galaxy M87 (Credit : Event Horizon Telescope) Image of the black hole at the centre of the galaxy M87 (Credit : Event Horizon Telescope)

    Sounds simple right but there are two major hurdles that stand in the way. First, scientists need to find a nearby black hole. Because black holes don’t emit or reflect light, they’re virtually invisible to telescopes. They can only detect by observing how they influence nearby stars or distort light. However, Bambi believes that new detection techniques could help locate a black hole within the next decade, possibly (and hopefully) just 20 to 25 light years from Earth.
    The second challenge is building the technology. Traditional spacecraft are far too heavy and slow for this journey. The proposed nanocrafts would need to survive decades in space while maintaining their ability to collect and transmit data.

    “We don’t have the technology now, but in 20 or 30 years, we might. The lasers alone would cost around one trillion euros today, and nanocraft technology doesn’t yet exist.” – Cosimo Bambi from Fudan University.

    But he remains optimistic, pointing to past “impossible” achievements. People said we’d never detect gravitational waves because they’re too weak. We did 100 years later. People thought we’d never observe the shadows of black holes. Now, 50 years later, we have images of two.

    While this mission may sound like the stuff of science fiction, it represents how scientific ambition pushes boundaries. Even if the full mission proves impossible, the technologies developed along the way could revolutionize space exploration and our understanding of the universe. The idea that we might one day touch the edge of a black hole, even if it is with a device smaller than a paperclip, captures the incredible potential of human curiosity and ingenuity reaching into the universe’s deepest mysteries.

    Source : An interstellar mission to a black hole? Astrophysicist thinks it’s possible.

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  • Will China’s new chromosome editing tool unlock new wave of genetic advances?

    Will China’s new chromosome editing tool unlock new wave of genetic advances?

    A group of Chinese scientists has overcome a challenge that stumped biologists for decades by developing a new gene-editing tool that can precisely manipulate millions of base pairs – the building blocks of DNA.
    The innovation has been hailed as “very significant progress” by Professor Yin Hao, a gene editing specialist at Wuhan University’s medical research institute, who was not involved in the study. He added that it would help lay the foundation for future advances in genetic engineering in biomedicine and agriculture.
    A single human cell contains around 3 billion base pairs. Well-known technologies such as Crispr are widely used for the precise editing of specific genes and nucleic acid bases. However, biologists have struggled to scale up the process to precisely manipulate thousands or even millions of bases.

    Now, a team led by Gao Caixia – a principal investigator at the Institute of Genetics and Developmental Biology at the Chinese Academy of Sciences in Beijing – has solved the riddle by making the decade-old gene editing tool much easier to use and more efficient. The study was published by the peer-reviewed journal Cell on Monday.

    The new genome editing technologies, collectively known as programmable chromosome engineering (PCE) systems, can edit large DNA fragments with precision by “handling bases ranging from the thousands to the millions in higher organisms, especially plants”, according to the institute.

    The toolset holds promise for transforming the way scientists conduct research in emerging fields such as agricultural seed cultivation and synthetic biology.

    According to a CAS branch institute in Beijing, by manipulating genomic structural variation, the technology will “open up new avenues for crop trait improvement and genetic disease treatment”.

    The advance could also accelerate the development of artificial chromosomes, which have promising applications in emerging fields such as synthetic biology.

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