Munich, Germany, 1 July 2025 – The new organisation of Airbus Defence and Space will come into effect on 1 July 2025, as previously communicated. The Division has completed all information and consultation processes on European as well as national levels for its adaptation plan and has reached productive agreements with its social partners.
This process followed an announcement in October 2024 to adapt the Division’s organisation and workforce in light of a continued complex business environment, especially in the Space Systems segment where significant financial charges were recorded in 2023 and 2024.
Among others, the company announced it would reduce up to 2,043 positions, predominantly management overhead functions, and provide stronger end-to-end accountability to its three business lines – Air Power, Space Systems and Connected Intelligence – in order to better cope with business requirements in the future.
“I thank our social partners and our Airbus Defence and Space colleagues for their constructive engagement and contributions throughout this process. Navigating organisational change is never straightforward for any party, particularly when it involves adapting our workforce. The current geopolitical landscape requires a stronger, faster and more resilient European defence and security industry. Our new structure delivers on this requirement through an efficient and effective end-to-end responsibility for our three businesses and a significantly optimised cost structure while preserving the ability and capacity to benefit from growing defence spending,” said Mike Schoellhorn, CEO Airbus Defence and Space.
As confirmed at the beginning of the information and consultation process, there will be no compulsory redundancies. The company is also committed to minimising the impact on its employees by utilising all available social measures.
BEIJING, July 1 (Xinhua) — Researchers have constructed a comprehensive 3D spatiotemporal multi-omics atlas of single cells throughout the entire developmental cycle of fruit flies, offering molecular-level insights into biological development.
The breakthrough is anticipated to advance research on developmental defects and related disease mechanisms. The study, a collaboration between BGI Research based in Hangzhou and the Southern University of Science and Technology in Shenzhen, has been published in the journal Cell.
Scientists describe animal development as an intricately orchestrated process in which genes and cells collaborate with spatiotemporal precision.
Using fruit flies as a model organism, they note its developmental cycle progresses through four well-defined phases: egg, larva, pupa and adult. This entire developmental process can be likened to a meticulously staged “living theater production,” where each cell’s entrance timing, spatial positioning, and subsequent transformation into specialized cell types are all meticulously regulated by genetic “scripts.”
The research team employed BGI’s self-developed technologies to conduct intensive sampling of fruit fly embryos at 30-minute to two-hour intervals, complemented by systematic sampling of larval and pupal stages at key developmental time points.
This strategy produced a massive dataset of more than 3.8 million spatially resolved single-cell transcriptomes spanning the entire life cycle.
Using Spateo, an algorithmic tool for spatiotemporal analysis, they reconstructed a high-resolution 3D model, precisely mapping the spatial dynamics of tissue morphology and gene expression. By integrating these data, the researchers built a differentiation trajectory map, uncovering fundamental molecular mechanisms governing cell fate decisions.
“Cells from different germ layers follow distinct differentiation paths. Transcription factors act as ‘cellular directors’, orchestrating differentiation by activating or repressing genes to assign specific roles to cells,” said Wang Mingyue, co-first author of the study.
Wang noted that multiple previously unknown transcription factors were identified, potentially playing critical roles in the nervous system, gut, and endocrine development.
Given that approximately 70 percent of human disease-related genes have counterparts in fruit flies, this research provides a powerful reference for studying human developmental diseases and offers new avenues for biomedical research, Wang said. ■
Discover the hottest new tools to study protein biology this August at the American Society for Biochemistry and Molecular Biology’s 15th International Symposium on Proteomics in the Life Sciences. This five-day symposium will be held August 17–21 at the Broad Institute of the Massachusetts Institute of Technology and Harvard University. Each day will be packed with scientific sessions, networking opportunities and more.
Kathryn Lilley
Meeting organizer Kathryn Lilley, a professor and group leader at the University of Cambridge, said she wants the symposium to give attendees a glimpse into the future of proteomics. She first attended this meeting more than a decade ago.
“Although I was in awe of all these very decorated colleagues — leaders in their field — everybody was super welcoming,” Lilley said.
The 2025 organizing committee includes Lilley; A. L. Burlingame, professor of pharmaceutical chemistry at the University of California, San Francisco; Steven Carr, senior director of proteomics at the Broad Institute; Ileana Cristea, director of graduate studies at Princeton University and ASBMB’s Molecular & Cellular Proteomics editor-in-chief; and Bernhard Küster, professor of proteomics and bioanalytics at the Technical University of Munich.
Lilley said this year’s conference will continue to foster that welcoming atmosphere while showcasing speakers with diverse expertise and offering a program that examines the proteome from all angles.
Top left, A.L. Burlingame; top right, Bernhard Küster; bottom left, Ileana Cristea; bottom right, Steven Carr.
Plenary talks from leaders in their fields will explore innovative proteomic and post-translational modification analyses in cancer and precision medicine, pioneering approaches in drug discovery through targeted protein degradation, and fresh insights into virus-host interactions that shape immune and metabolic responses. Lilley hopes attendees will discover unexpected opportunities to collaborate.
“These sets of speakers don’t necessarily come together in a lot of the larger meetings in our field, so I think that itself is very interesting and very empowering,” she said. “You’ll get people who have not met but will see some sort of alignment in their research programs and their methodologies.”
In addition to plenary and session talks, organizers will select a few abstracts for short talks. Most abstract submitters will have the opportunity to present a poster.
“Everybody takes it very seriously, and every poster will get a lot of interest and a lot of traffic,” she said.
Looking ahead, the program will take a holistic view of the field and highlight emerging areas such as spatial proteomics, single-cell proteomics, multiomics, proteoforms and immunopeptidomics.
“There’s going to be an element of crystal ball gazing and future-proofing proteomics as well,” she said.
Lilley encouraged researchers new to proteomics to attend and explore how these techniques might expand and diversify their work.
“Everybody, whatever career stage they are, needs to have their horizons expanded to be able to look for new opportunities,” she said. “This meeting is a great place to do just that.”
The regular registration deadline is July 23. Register today!
Cambridge, Massachusetts
Plenary Lectures
“Motif-based approaches for analyzing phosphoproteomic mass spectrometry datasets identify signaling dependencies in cancers lacking known oncogenic drivers” | Michael MacCoss, University of Washington
“Shedding light on the dark viral proteome to advance our understanding of antiviral immunity” | Shira Weingarten–Gabbay, Harvard Medical School
“Protein degraders: New insights and twists of molecular mechanism and drug design” | Alessio Ciulli, University of Dundee
“Studying the mechanisms and cellular processes regulated by protein post-translational modifications” | Pedro Beltrao, Institute of Molecular Systems Biology, ETH Zurich Laboratory
“Phosphoproteomics as a functional molecular read-out for personalized precision oncology” | Connie Jimenez, Amsterdam University Medical Center
“The interface between metabolism and immunity within a virus microenvironment” | Ileana Cristea, Princeton University
Nvidia’s DLSS upscaling technology is the most exciting thing happening in gaming that sounds like the least exciting thing. I’ve been crowing about what an amazing tool DLSS is for years, going all the way back to when we thought the Switch 2 was just the Switch Pro.
I mean, I guess it kind of is… but I digress.
DLSS 4 released alongside the newest generation of 50-series GPUs, and I’ve been putting some of the new features through their paces to find out if they’re everything Nvidia says they are. In particular, I was interested to see how multi-frame generation, which now supports 4x on 50-series cards, can be used to improve performance and visual fidelity beyond my system’s normal limits. After much testing, it’s safe to say the marketing isn’t deceptive: DLSS 4’s multi-frame generation is so good at creating frames out of thin air, it practically looks like magic.
You Get Some Frames, And You Get Some Frames
A lot of graphics and gaming tech is hard to parse because it sounds like a bunch of technobabble, but multi-frame generation is exactly what it sounds like. While DLSS, or deep-learning super sampling, boosts performance by running your game at a low resolution using AI to infer a higher quality image, multi-frame generation uses AI to, well, generate more frames. Nvidia gets into the nitty-gritty of how it’s able to do that here, but what I’m really interested in is whether it or not it actually works, and what drawbacks, if any, it comes with.
To test multi-frame generation, Nvidia provided me with an RTX 5080, Doom: The Dark Ages, and Dune: Awakening, to see how the feature works in both single player and multiplayer settings. There are already 100 games that support multi-frame generation, with new releases like Mecha Break, Phantom Break Zero, and Tides of Annihilation on the way, but between Doom and Dune, I got a pretty good sense of what DLSS 4 has to offer modern games. I also tested God of War Ragnarok and Spider-Man 2 to see what the tech does for slightly older games too.
RTX 40-series cards don’t support multi-frame generation, but still offer 2x frame generation.
Doom: The Dark Ages is one of the most frenetic shooters out there, so multi-frame generation would have to be pretty precise to keep up with the Slayer’s rampage. As a basic test I started with DLSS in balanced mode and tuned my settings until I got a stable 60fps. I use a 5120×2160 super ultrawide display, so even with a 5080 slotted in, locking in at 60 is a lot easier than it sounds.
On 50-series cards multi-frame can scale from 2x to 4x, so I turned on 2x and voila, 120fps. I skipped 3x and went right to 4x, and what do you know, 240fps. One click of a button, and my framerate quadrupled. Could this be true? Is it really that simple? Well, yes and no, but mostly yes.
Could It Really Be That Easy?
Going from 60fps to 240 with the click of a button is pretty incredible. As someone who has been PC gaming since the ‘90s and has spent hours tweaking shadow settings to squeeze two extra frames out of my rig, I couldn’t believe how easy this was. No really, I couldn’t believe it.
I played hours of Doom: The Dark Ages, and my conclusion is that multi-frame generation is incredible, but it’s not perfect. You will find some occasional artifacting if you’re looking for it, especially in things that are difficult to render like detailed foliage or when objects move out from behind UI. Even around the target reticle, which is where your focus is when locked when you’re playing, you can see some of the calculations happening in front of your eyes, depending on what you’re aiming at. The flaws are the most notable on 4x, while on 2x, I barely noticed any flaws at all.
The other thing to consider is that using multi-frame generation increases latency. This won’t be a huge deal in some games, but for something super twitchy like Doom, it can feel a little bit floaty. The latency didn’t bother me nearly as much in Spider-Man or God of War, but I definitely noticed it in Doom. While getting lots of free frames may sound great for competitive shooters, because of the latency, I wouldn’t recommend this feature for Marvel Rivals or Apex Legends players.
But for something like Dune: Awakening, it’s incredible. The smoothness you get from having a higher frame rate has a big impact. Driving and flying across the desert is that much more immersive, and the scale of the world, along with its muted color palette, makes any potential flaw a lot harder to detect. Of all the games I tested, Dune was the most impressive.
Who Is Multi-Frame Generation For?
My first instinct when I learned about multi-frame generation was that, like DLSS itself, it would help future proof our gaming PCs. It doesn’t matter if your hardware is too low to hit a stable 30 when you can hit one button and turn 30 into 120. It turns out that, at least for now, low end machines won’t get as much out of multi-frame generation as machines that can already hit a decent frame rate. Going from 30 to 120 introduces significantly more artifacting than going from 60 to 240, simply because your starting point is so much lower.
That doesn’t mean it’s useless for low-end machines, and different people will have different sensitivities to defects. There’s a good chance you will be able to squeeze more life out of lower end 4060 and 5060 GPUs thanks to this feature, because the benefits will be worth more than the sacrifices.
The best use for multi-frame generation seems to be maxing out the refresh rate of your display. My monstrous super ultrawide has a 240Hz refresh rate that I’ve never been able to take advantage of, but with multi-frame generation, I can finally get there. It’s not uncommon for gamers to have 120, 240, or even 360Hz displays these days, and for modern triple-A games, this is the only way you’re going to be able to hit those kinds of numbers.
Is multi-frame generation a magical make more frames button? Well yeah, it kind of is. When you consider the drawbacks, it’s pretty impressive how much more you can get out of your rig. After three years with the Samsung Odyssey G9, I’m finally getting to see its full potential thanks to this feature, and this is only the start.
Date Founded
April 1, 1993
CEO
Jensen Huang
Subsidiaries
Mellanox Technologies, Cumulus Networks, NVIDIA Advanced Rendering Center
Pakistan’s Permanent Representative to UN Ambassador Asim Iftikhar Ahmad speaks during a UNSC session on July 1, 2025. — X@PakistanUN_NY
Pakistan on Tuesday assumed the role of president of the United Nations Security Council (UNSC) for the month of July — marking a key step in the country’s progress and achievement in the diplomatic domain.
The development, as confirmed by Foreign Minister Ishaq Dar in a post on X, comes weeks after Pakistan was named vice-chair of the United Nations Security Council’s (UNSC) Counter-Terrorism Committee, tasked with overseeing implementation of resolution 1373 (2001) concerning international anti-terror efforts.
The country, back in January earlier this year, had begun its eighth term for two years (2025-26) as a non-permanent member of the 15-member body.
The UNSC has 15 members, five of which — Britain, China, France, Russia, and the United States — are permanent ones. The 10 non-permanent seats of the Council are allocated by geographic region, with five replaced each year.
The key UN body is considered to be the most powerful body of the United Nations. The council, which is tasked to maintain international peace and security, can make legally binding decisions and has the power to impose sanctions and authorise the use of force against states.
“Today, Pakistan assumes the Presidency of the UN Security Council for July 2025, during its 8th term (2025–26) as an elected member of the UNSC,” Foreign Minister Ishaq Dar said in a post on X.
“Pakistan takes on this responsibility with humility, conviction and profound commitment to the UN Charter, international law, and multilateralism,” the FM added while further highlighting that the country’s role as UNSC president comes “at a time of escalating conflicts and humanitarian crises across the world”.
“We will strive to steer the Security Council towards responsive and effective action grounded in dialogue, diplomacy and peaceful dispute resolution,” he remarked.
Apart from the UNSC presidency, Pakistan’s Permanent Representative to the UN, Ambassador Kamran Akhtar has also been elected as President of the 53rd session of the Industrial Development Board (UNIDO) — marking the first such instance for Islamabad.
“The director general of UNIDO, while congratulating Ambassador Kamran Akhtar, praised Pakistan’s commitment and contribution to the organisation,” the Foreign Office said in a statement.
Meanwhile, Ambassador Akhtar in his statement thanked all UNIDO member states for their trust and expressed his commitment towards further enhancing the Organization’s role in industrial development, particularly in developing countries, LDCs, and SIDS.
“The election manifests the trust reposed in Pakistan by the UNIDO Member States. Like all Vienna-based international organizations, Pakistan maintains an active diplomatic profile at UNIDO and remains committed to the organization’s core mandate, which is inclusive and sustainable Industrial Development,” the FO added, further highlighting that the country had one of the largest portfolios with UNIDO, with several ongoing and planned projects worth over €350 million.
Furthermore, the UN body has supported Pakistan’s textile, leather, fisheries, food safety, climate action, and renewable energy sectors with projects like PAIDAR and PAFAID have helped in poverty alleviation, job creation, and the sustainable growth of rural communities.
