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  • Why the Mediterranean Diet Is So Good for Your Brain

    Why the Mediterranean Diet Is So Good for Your Brain

    • The Mediterranean diet may boost cognition & reduce your risk of developing dementia and depression.
    • The diet is full of plant polyphenols and omega-3 fatty acids that help reduce inflammation.
    • Choose healthy cooking methods, such as grilling or roasting, and eat fruit for dessert.

    The foods you eat play an essential role in staying sharp as you age, and nutrient-packed, flavor-rich and easy-to-follow eating patterns like the Mediterranean diet make the job easier. A smattering of studies reveals just how this eating plan can be a boon to your brain health and mood today—and in the future. Oh, and there are happiness benefits, too.

    So what exactly happens to your brain when you follow the Mediterranean diet?

    How the Mediterranean Diet Benefits Your Brain

    Promising research shows that the Mediterranean diet may boost brain health in a few key ways: by improving factors like memory, decreasing the risk of cognitive decline and bettering mood. Here’s a deeper look.

    It May Improve Your Cognitive Capabilities

    Incorporating the principles of the Mediterranean diet can shore up your smarts. Multiple long-term studies have found that those who more closely followed the Mediterranean diet had better cognitive function. Furthermore, consuming olive oil, a staple of the Mediterranean diet, has been shown to improve cognitive functioning. Eating more fish and less meat is also associated with positive brain outcomes, thanks to fish’s omega-3 fatty acids, which protect blood vessels in the brain, quell damage from oxidative stress and reduce inflammation.

    And there’s more. Another study found that following the Mediterranean diet is a promising intervention for improving cognitive impairment in individuals with type 2 diabetes. By improving insulin sensitivity, stabilizing glucose levels, improving cerebrovascular functioning and improving lipid metabolism, the Mediterranean diet may reduce the risk of complications from diabetes.

    It May Help You Prevent Dementia

    Though various factors are at play that govern cognitive decline, a healthy diet may help tip the scales in your favor. Both the Mediterranean diet and the MIND diet (a diet similar to the Mediterranean diet, but more focused on foods and nutrients specifically known to support brain health) have been shown in randomized controlled trials to slow the rate of cognitive decline.

    For example, one study found that people who had the greatest adherence to a Mediterranean diet had a 72% decreased risk of developing dementia compared to those with the lowest adherence. In that same study, the higher the score one had on a scale that measured adherence to the Mediterranean diet, the younger, or healthier, their brains seemed.

    Another study found that those who followed the Mediterranean diet had a 11-30% reduced risk of developing cognitive disorders, including dementia and Alzheimer’s disease. Though exactly why is still being studied, the Mediterranean diet limits red meat and highly processed foods rich in refined carbohydrates, added sugars and saturated fat. These types of foods may be more likely to increase the risk of heart disease, insulin resistance and inflammation, which may speed brain aging.

    It May Decrease Your Risk of Depression

    Sticking to an eating pattern with similar components as the Mediterranean diet may help keep your mood up. One study found that adherence to the Mediterranean diet reduced the symptoms of depression in young and middle-aged adults with major depression or depressive symptoms. Inflammation may be one of the factors driving depression, and the Mediterranean diet promotes foods packed with anti-inflammatory nutrients from plant-based oils and nuts, fruits and vegetables. Some vegetables with the highest anti-inflammatory properties include broccoli, tomatoes, edamame, peppers, collard greens and mushrooms.

    More specifically, another study showed that subjects who adhered to the Mediterranean diet the most had 40% and 39% lower odds for depression and anxiety, respectively, compared to those who were the least able to follow the diet pattern. Specifically, eating more fruits and veggies was found to buoy one’s mood the most. The Mediterranean diet is rich in fiber, heart-healthy monounsaturated fats, magnesium and B vitamins, all of which have been shown in prior research to benefit psychological health.

    Is the Mediterranean Diet Right for Everyone?

    Cognitive health, dementia and depression are all multifactorial, meaning that many variables —from genes to lifestyle habits, such as diet, exercise or smoking, as well as chronic conditions—are risk factors for these diseases that affect your brain. Though incorporating the principles of the Mediterranean diet in a way that fits your culture and preferences is essential, diet alone isn’t the answer. What’s more, other aspects of the Mediterranean lifestyle, such as strong social ties, rest and regular movement, are also important for brain health.

    5 Ways to Enjoy Eating the Mediterranean Diet

    What foods should you eat for your noggin? There are so many possibilities in a Mediterranean diet—fruits, vegetables, whole grains, beans and legumes, nuts and seeds, lean protein and healthy fats. And the healthy eating principles of the diet can be applied to any type of cuisine—you don’t need to only eat foods and dishes from Mediterranean countries like Italy, Spain and Greece to gain the health benefits. Here are a few brain-supporting foods to try to fit into your routine.

    • Fish: Fish is a staple protein on the Mediterranean diet. Opt for healthy preparation methods, such as grilling, broiling and baking.
    • Plant-based oils: Oils such as olive oil, avocado oil and chia seed oil are packed with heart-healthy fats. Olive oil contains anti-inflammatory components that not only directly impact your brain but may also play a role in the health of your gut microbiome, which can also help protect your brain. Chia seed oil contains plant-based omega-3 fatty acids to reduce overall inflammation.
    • Green leafy vegetables: Whether in a salad, stirred into soups or pasta dishes or as a sandwich filler, greens such as spinach, kale, lettuces and arugula are essential on the Mediterranean diet.
    • Fruits: Fruits are eaten as part of sweet and savory dishes in the Mediterranean diet. Whether fresh, pureed, dried or frozen, they are enjoyed in abundance.
    • Pasta: In all shapes and sizes, pasta is enjoyed in the Mediterranean diet. It is often used as a vessel to consume more vegetables, olive oil, herbs and spices.

    Our Expert Take

    Incorporating the principles of the Mediterranean diet may be beneficial in preserving your cognitive health, decreasing your risk of depression and supporting your overall mental health. And the best news is, because the principles of the diet can be applied to any type of cuisine, there are so many delicious ways to enjoy this eating pattern.

    Frequently Asked Questions


    • What lifestyle factors impact the Mediterranean diet?

      The Mediterranean diet is more than food. The lifestyle of the Mediterranean and the cognitive benefits that come from it are rooted in the food, social interaction, everyday movement and quality rest.


    • What foods are included on the Mediterranean diet?

      The Mediterranean diet is primarily filled with plant foods. Vegetables, fruits, legumes, beans, nuts, seeds and whole grains are abundant in the Mediterranean diet. Seafood is an important protein, but other lean meats, such as chicken, pork and beef are also consumed in smaller amounts.


    • What are the other health benefits with the Mediterranean diet?

      The Mediterranean diet has been studied for decreasing the risk of heart disease, obesity, neurodegenerative disease, cancer and type 2 diabetes mainly through the high levels of polyphenols and antioxidants that have anti-inflammatory properties.

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  • Chris Martin Tells Coldplay Fans To Send Love To Charlie Kirk’s Family

    Chris Martin Tells Coldplay Fans To Send Love To Charlie Kirk’s Family

    As the killing of Charlie Kirk sparks mass partisan fallout, it seems Chris Martin is trying to keep the peace with a message of love.

    During the band’s final stop on their Music of the Spheres World Tour on Friday in London, the Coldplay frontman encouraged the audience to send love “to Charlie Kirk’s family” following the conservative influencer’s death this week.

    “Let’s raise our hands like this and send love anywhere you wanna send it in the world, and there are so many places that might need it today,” he said onstage at Wembley Stadium. “So, here it comes from London. You can send this to your brother or sister, you can send it to the families of people who have been going through terrible stuff.”

    Martin continued, “You can send it to Charlie Kirk’s family, you can send it to anybody’s family. You can send it to people you disagree with, but you send them love anyway. You can send it to peaceful people in the Middle East and Ukraine and Russia and Azerbaijan and Sudan and London, anywhere you think might need love from London. Here it comes.”

    Kirk, a conservative influencer and the co-founder of Turning Point USA, died at age 31 after he was shot in the neck from a nearby building during an outdoor speech at Utah Valley University on Wednesday. On Friday, 22-year old Utah local Tyler Robinson was arrested for the shooting.

    While politicians and public figures on both sides of the aisle have condemned the act of political violence, many have called attention to Kirk’s divisive public stances, which he advocated through his student organization Turning Point USA.

    President Donald Trump has since shared a statement, blaming the shooting on the “radical left,” adding: “This type of rhetoric is directly responsible for the terrorism that we’re seeing in our country today, and it must stop right now.”

    “My administration will find each and every one of those who contributed to this atrocity, and to other political violence, including the organizations that fund it and support, as well as those who go after our judges, law enforcement officials and everyone else who brings order to our country,” added Trump.


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  • Premier League 2025-26: Tottenham Hotspur deepens West Ham United’s woes with 3-0 win

    Premier League 2025-26: Tottenham Hotspur deepens West Ham United’s woes with 3-0 win

    Tottenham Hotspur cruised to a comprehensive 3-0 win over West Ham United on Saturday to leave the home side languishing in the Premier League bottom three, with the Hammers suffering another blow as midfielder Tomas Soucek was sent off for a dangerous tackle.

    Christian Romero had the ball in the net for Spurs with a header from a corner in the 19th minute, but the goal was immediately ruled out by referee Jarred Gillett for a push in the build-up, with the VAR confirming his decision as correct.

    With Tottenham sensing weakness, the West Ham penalty area resembled a wrestling ring at every set piece, and it could have easily conceded a penalty for some overzealous grappling as it struggled to keep track of the Spurs players.

    When the visitor took the lead in the 47th minute, it predictably came from a set piece as Pape Matar Sarr was left unmarked at the back post, and he sent a powerful header from a Xavi Simons corner flying into the net.

    ALSO READ | Arsenal wins 3-0 to spoil Postecoglou’s debut as Nottingham Forest coach

    Soucek was then shown a straight red card for a horrendously timed studs-up challenge on Joao Palhinha that ripped the sock of the Spurs player, and any chance of a comeback evaporated with his dismissal.

    Spurs worked the resulting free kick across the field for Lucas Bergvall to score his first Premier League goal with a looping header from Romero’s cross, and the Swedish midfielder then teed up Micky Van de Ven for the third in the 64th minute.

    Down to 10 men, West Ham was pinned back for much of the rest of the game, barely threatening the Spurs goal as it slumped to its third league defeat of the season.

    The win moves Spurs up to second in the table on nine points and leaves West Ham in 18th with three points from its first four games.

    Published on Sep 14, 2025

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  • How Physical Stress Pushes Cancer Cells Into Dangerous New States

    How Physical Stress Pushes Cancer Cells Into Dangerous New States

    New research shows that the physical pressure of surrounding tissues can trigger hidden epigenetic changes in cancer cells, making them less focused on growth but more invasive and resistant. Credit: Stock

    Pressure from surrounding tissues activates invasive programs in cancer cells. This mechanical stress rewires epigenetic regulation.

    Cancer cells are notoriously adaptable, capable of shifting their characteristics as they spread throughout the body. Many of these shifts stem from epigenetic changes, which influence how DNA is organized and expressed rather than altering the genetic code itself. Because such changes are reversible and can switch on and off, they are particularly challenging to target in cancer therapies.

    Traditionally, epigenetic alterations were believed to result mainly from processes inside the cell, such as the chemical tagging of DNA and its associated histone proteins, including mechanisms like histone methylation or DNA acetylation. However, a new study led by Richard White of Ludwig Oxford and Miranda Hunter of Memorial Sloan Kettering Cancer Center, published in Nature, reveals that the physical conditions surrounding cancer cells are also powerful triggers of epigenetic change.

    Mechanical stress and HMGB2

    Working with a zebrafish model of melanoma, White, Hunter, and their collaborators found that tumor cells under tight physical confinement undergo dramatic structural and functional shifts. Instead of multiplying rapidly, these cells switch to a program of “neuronal invasion,” which equips them to migrate and infiltrate surrounding tissue.

    Central to this transformation is HMGB2, a protein that bends DNA. The study shows that HMGB2 responds to confinement-induced mechanical stress by binding to chromatin, reshaping how genetic material is packaged. This reorganization exposes genome regions linked to invasive behavior, making them available for expression. As a result, cells with elevated HMGB2 lose some of their proliferative capacity but become more invasive and resistant to therapy.

    Remodeling under pressure

    The team also found that melanoma cells adapt to this external pressure by remodeling their internal skeleton, forming a cage-like structure around the nucleus. This protective shield involves the LINC complex, a molecular bridge that connects the cell’s skeleton to the nuclear envelope, helping to protect the nucleus from rupture and DNA damage caused by confinement-induced stress.

    “Cancer cells can rapidly switch between different states, depending on cues within their environment,” White explained. “Our study has shown that this switch can be triggered by mechanical forces within the tumor microenvironment. This flexibility poses a major challenge for treatment, as therapies targeting rapidly dividing cells may miss those that have transitioned to an invasive, drug-resistant phenotype. By identifying the factors that are involved in this switch, we hope to be able to develop therapies that prevent or even reverse the invasive transformation.”

    The findings highlight the role of the tumor microenvironment in shaping cancer cell behavior, showing how physical cues can drive cells to reorganize their cytoskeleton, nucleus, and the architecture of their genomic packaging to shift between states of growth and invasion.

    Most notably, however, the study also demonstrates how physical stress can act as a potent—and underappreciated— driver of epigenetic change.

    Reference: “Mechanical confinement governs phenotypic plasticity in melanoma” by Miranda V. Hunter, Eshita Joshi, Sydney Bowker, Emily Montal, Yilun Ma, Young Hun Kim, Zhifan Yang, Laura Tuffery, Zhuoning Li, Eric Rosiek, Alexander Browning, Reuben Moncada, Itai Yanai, Helen Byrne, Mara Monetti, Elisa de Stanchina, Pierre-Jacques Hamard, Richard P. Koche and Richard M. White, 27 August 2025, Nature.
    DOI: 10.1038/s41586-025-09445-6

    This study was supported by the Ludwig Institute for Cancer Research, National Cancer Institute, the Cancer Research Society, the Canadian Institutes of Health Research, the U.S. National Institutes of Health, the Melanoma Research Alliance, The Debra and Leon Black Family Foundation, the Pershing Square Sohn Foundation, The Mark Foundation, The Alan and Sandra Gerry Metastasis Research Initiative at MSKCC, The Harry J. Lloyd Foundation, Consano, the Starr Cancer Consortium and the American Cancer Society.

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  • Pakistan exude calm ahead of emotionally-charged India clash – Sport

    Pakistan exude calm ahead of emotionally-charged India clash – Sport

    DUBAI: An India-Pakistan cricket match is always a blockbuster but emotions will run even higher in Sunday’s Asia Cup clash between the nuclear-armed neighbours, who engaged in a four-day military conflict earlier this year.

    Even before the clashes in May, which nearly escalated into a full-blown war, bilateral cricket ties had been suspended. The arch-rivals now play each other only in multi-team tournaments.

    Political relations have deteriorated further since the clashes, with several former Indian players urging the Board of Control for Cricket in India to boycott what will be the first meeting between the teams since the recent hostilities.

    While the threat of a boycott is over, sparks may fly with India captain Suryakumar Yadav and his Pakistan counterpart Salman Agha ruling out dialling down aggression in the much-anticipated Group ‘A’ fixture.

    However, Pakistan opener Saim Ayub exuded calm in the pre-match news conference ahead of the geopolitically-charged clash.

    “It’s a big game but we aren’t thinking too much about it,” Saim told reporters on Friday. “We’re using the same processes and trying to improve things in our execution.”

    Saim was also not dwelling on the past encounters between the two teams, where India have enjoyed the upper hand.

    Asked about being on the sidelines for the 2024 T20 World Cup clash between the two sides, which India won, Saim said he “didn’t remember too much about that game”.

    “I think in the last three to four months, the message [from the team management] has been that we learn from the past and move forward,” he added. “It’s not about what happened yesterday but we will try to do things better tomorrow.

    “[Past] memories don’t matter. We’re not just looking forward to the match against India … we are looking to win the tournament.”

    Pakistan have dropped former skippers and batting stalwarts Babar Azam and Mohammad Rizwan with new coach Mike Hesson trying to promote a fearless brand of cricket in the new-look side.

    Asked if the Pakistan team will do the same in the India clash, Saim said: “We try to play fearless cricket against everyone.”

    Indian batter Shubman Gill gestures during a practice session at the International Cricket Council Academy on Sept 13, 2025 in Dubai. — AFP

    Like Saim, fellow batter Mohammad Haris — who shone in Pakistan’s tournament-opening win against Oman — wasn’t losing his sleep over the India fixture.

    “We are going to rest tomorrow and then we will see on Sunday,” he told reporters following the thumping 93-run victory on Friday.

    India, the reigning T20 world champions, enter the match as favourites and were ruthless in their nine-wicket demolition of the United Arab Emirates.

    India’s fielding coach Ryan ten Doeschate had no qualms in accepting his side’s status as the favourites. They have won 18 of their 21 T20Is since winning the world title in June last year and 10 of their 13 matches against Pakistan.

    “Our record is pretty incredible,” he told reporters on Saturday. “On recent form and how we’ve have played, India do start as favourites. But it is all about that particular day. The team who does well in the 240 deliveries will win.”

    BOYCOTT CALLS

    There have been widespread calls in India to ban any sporting ties with Pakistan but Ten Doeschate said the team has been instructed to strictly follow the directives of the BCCI and the Indian government.

    New Delhi only cleared the match in a recently announced sports policy, saying the Indian national team can play Pakistan in multi-national events but not in bilateral competitions.

    Asked how the Indian players will react, he termed it a “sensitive issue”.

    “The players share the compassion and the feeling of the vast majority of the Indian public,” he said. “Hopefully the way we play; the players represent how they feel about their country.”

    Ten Doeschate added that head coach Gautam Gambhir has called for focus on the game.

    “Our thing is, you separate sports and politics,” he said. “I understand the sentiment but we are following directives of BCCI and government. We are going by what the government and BCCI told us.

    “The Asia Cup was in limbo for a long period of time and we didn’t think we’d be coming at one stage but obviously the Indian government stance in it and now you have to put the sentiment and emotions behind … it’s something we addressed in the team meeting today.”

    “Gambhir’s message is to not focus on things not in your control. Messaging is to focus on cricket.”

    India have reinforced themselves for the Asia Cup with the selection of pace spearhead Jasprit Bumrah and top order batter Shubman Gill.

    The clash could be the first of three as both India and Pakistan are favourites to qualify for the Super Four stage and possibly for the September 28 final.

    Ten Doeschate said India have done their homework against Pakistan. “Pakistan have decided to change their direction to how they play their cricket,” he said.

    Pakistan, meanwhile, believe that they have the team that can win.

    “As a team, we trust each other,” the explosive Saim said, when asked about his lack of form with the bat. “It’s a long-term process of raising confidence so that anyone in the team can be a match-winner on his day. It’s about effort and we’re trying to give our all to give the best results.”

    Published in Dawn, September 14th, 2025

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  • Jepchirchir pips Assefa to world marathon title in Tokyo | News | Tokyo 25 – worldathletics.org

    1. Jepchirchir pips Assefa to world marathon title in Tokyo | News | Tokyo 25  worldathletics.org
    2. Peris Jepchirchir leads Kenya’s chase for women’s marathon title  Daily Nation
    3. Highlights of World Athletics Championships in Tokyo  Xinhua
    4. Live Blog: USA’s Sullivan commands lead as global stars battle in the chase  mozzartsport.co.ke
    5. Peres back in Japan with hopes of another gold medal  standardmedia.co.ke

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  • SL cruise to six-wicket win over Bangladesh – Newspaper

    SL cruise to six-wicket win over Bangladesh – Newspaper

    ABU DHABI: Sri Lankan players celebrate the dismissal of Bangladesh batter Towhid Hridoy during their Asia Cup match at the Sheikh Zayed Cricket Stadium on Saturday.—AFP

    ABU DHABI: Former champions Sri Lanka launched their Asia Cup campaign in emphatic fashion on Sunday, cruising to a six-wicket victory over Bangladesh in Abu Dhabi.

    Chasing 140, the islanders got home with 32 balls to spare.

    A blazing 95-run stand off just 52 deliveries for the second wicket between Pathum Nissanka (50) and Kamil Mishara provided the backbone of the innings.

    Mishara arrived at the crease after Kusal Mendis fell in the second over. He took time to settle but soon cut loose, cracking Shoriful Islam for three consecutive boundaries.

    Nissanka compiled his 16th half-century before holing out in the deep. By then Sri Lanka had the game firmly in their grip.

    Mishara, a newcomer to the side, remained unbeaten on 46 to see his team across the line.

    The platform for the win was earlier built by Sri Lanka’s bowlers, who throttled Bangladesh to under 139-5 from their 20 overs.

    Dushmantha Chameera and Nuwan Thushara struck with the new ball, sending down two maidens and removing both openers. By the third over, Bangladesh were nought for two and never recovered.

    Sri Lanka’s fielders played their part too with Mishara’s direct hit from deep square leg running out Towhid Hridoy to deepen the rot.

    At 53-5 at halfway, Bangladesh were reeling as leg-spinner Wanindu Hasaranga, returning from injury, stamped his class with two for 25.

    A spirited unbroken 86-run stand for the sixth wicket between Jaker Ali (41) and Shamim Hossain (42) gave Bangladesh something to bowl at, but it was never enough to trouble Sri Lanka’s powerful batting unit.

    Sri Lankan skipper Charith Asalanka was glad the way his team started their campaign.

    “The first two overs [of the Bangladesh innings] were a key moment for us, set the platform. It was a dream start,” he said.

    Commenting on Hasaranga’s googly, Asalanka said, “That is his main weapon, even we can’t pick him. He’s a superstar.

    “Once we got 115-120, we wanted to finish the game as soon as possible. It’s absolutely brilliant support from the fans, Bangladesh fans as well. I just want to thank every fan that came out to support us,” the skipper continued.

    Mishara said that he was waiting for the right time to up the ante.

    “We knew that we had to just score seven runs an over and when I walked in Pathum [Nissanka] asked me to take my time. Once the loose balls were on offer, I played a few shots. I have been working very hard on my game. Happy to have helped my country win a game,” Mishara said.

    Liton Das, the Bangladesh captain, said that his batters should have scored more.

    “This is not a 140 pitch. We should have scored much more than that. They put us under pressure during the powerplay and we never recovered,” wicket-keeper/batter Liton, who scored 28 off 26 balls, said after the match. “Our next game against Afghanistan is a must win clash. We will try our best.”

    Defending champions in the T20 format, Sri Lanka now head to Dubai for their next clash against Hong Kong on Monday.

    Scoreboard

    BANGLADESH:
    Tanzid Hasan b Thushara0
    Parvez Hossain c Kusal Mendisb Chameera0
    Liton Das c Kusal Mendis b Hasaranga28
    Towhid Hridoy run out8
    Mahedi Hasan lbw b Hasaranga9
    Jaker Ali not out41
    Shamim Hossain not out42

    EXTRAS (B-2, LB-3, W-6)11
    TOTAL (for five wickets, 20 overs)139
    DID NOT BAT: Rishad Hossain, Tanzim Hasan, Shoriful Islam, Mustafizur Rahman
    FALL OF WICKETS: 1-0 (Tanzid), 2-0 (Parvez), 3-11 (Towhid), 4-38 (Mahedi), 5-53 (Liton)
    BOWLING: Thushara 4-1-17-1; Chameera 4-1-17-1 (1w); Shanaka 3-0-27-0; Pathirana 4-0-42-0 (4w); Hasaranga 4-0-25-2; Asalanka 1-0-6-0

    SRI LANKA:
    P. Nissanka c Shoriful b Mahedi50
    Kusal Mendis c Liton b Mustafizur3
    K. Mishara not out46
    K. Perera lbw b Mahedi9
    D. Shanaka c Mustafizur b Tanzim1
    C. Asalanka not out10

    EXTRAS (LB-5, W-16)21
    TOTAL (for four wickets, 14.4 overs)140
    DID NOT BAT: Kamindu Mendis, W. Hasaranga, D. Chameera, M. Pathirana, N. Thushara
    FALL OF WICKETS: 1-13 (Kusal Mendis), 2-108 (Nissanka), 3-123 (Perera), 4-126 (Shanaka)
    BOWLING: Shoriful 3-0-26-0 (2w); Mustafizur 3-0-35-1 (2w); Tanzim 3-0-23-1 (1w); Mahedi 4-0-29-2; Rishad 1-0-18-0 (2w); Shamim 0.4-0-4-0

    RESULT: Sri Lanka won by six wickets.
    MAN-OF-THE-MATCH: Kamil Mishara

    Published in Dawn, September 14th, 2025

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  • Postpartum Expulsion of an Infected Intramural Uterine Myoma: Rapid Growth in Pregnancy and Definitive Management by Abdominal Hysterectomy

    Postpartum Expulsion of an Infected Intramural Uterine Myoma: Rapid Growth in Pregnancy and Definitive Management by Abdominal Hysterectomy


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  • Immune Checkpoint Inhibitor-Induced Type 1 Diabetes Mellitus in a Patient With Melanoma: A Case Report

    Immune Checkpoint Inhibitor-Induced Type 1 Diabetes Mellitus in a Patient With Melanoma: A Case Report


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  • Cassava starch patch breakthrough in Kerala could aid treatment of mouth disorders, oral cancer

    Cassava starch patch breakthrough in Kerala could aid treatment of mouth disorders, oral cancer

    Cassava starch patch offers cost-effective, long-lasting treatment for oral disorders including leukoplakia and injuries.

    Cassava starch patch breakthrough in Kerala could aid treatment of mouth disorders, oral cancer
    Cassava starch patch- Cassava | Photos: Mathrubhumi, Canva

    Thiruvananthapuram: Scientists have made a breakthrough in the treatment of mouth disorders and injuries. A patch made from cassava starch has been developed to prolong the effect of medicines for white patches (leukoplakia) and other conditions. The small, film-like patches are being developed through joint research at Sree Chitra Tirunal Institute for Medical Sciences and Technology and the Central Tuber Crops Research Institute (CTCRI).

    Leading scientists at the forefront

    CTCRI Principal Scientist Dr A.N. Jyothi and Sree Chitra scientist Dr Manoj Komath are leading the experiments. CTCRI is handling the manufacturing of the starch sheets, determining the correct drug dosage, and ensuring proper integration into the films. Once ready, the patches will be sent to Sree Chitra for trials related to oral application.

    Potential impact on cancer treatment

    The research is expected to assist even in cancer treatment. The cassava starch is ground into a paste to create patches that can adhere inside the mouth, similar to a plaster. Trials showed that the patches remain in place for up to two hours without causing discomfort. They do not loosen when rinsing the mouth or swallowing. Even if swallowed, it is not unsafe.

    Cost-effective alternative to existing treatments

    Unlike ointments, powders, or mouthwashes, which do not remain in the mouth for long, existing cellulose-fibre-based patches can last longer but are more expensive. This new cassava starch patch offers a cost-effective and patient-friendly alternative.

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