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  • Regional differences found in newborn antibiotic use for suspected sepsis in Sweden

    Regional differences found in newborn antibiotic use for suspected sepsis in Sweden

    There are relatively large regional differences in Sweden in the proportion of newborns receiving antibiotics for suspected sepsis, according to a study at the University of Gothenburg. The researchers want to call attention to overuse as well as highlight good examples.

    When newborns receive antibiotics, it is almost always for suspected sepsis. Despite Sweden’s low antibiotic use compared to other countries, last year researchers found unjustifiably high usage levels in newborns. The gradual decline in sepsis prevalence over time has not affected antibiotic use.

    This new study provides an overview of antibiotic use in six major regions in Sweden. The dataset also includes the corresponding data from individual hospitals with neonatal units where newborns are treated, a total of 37 hospitals, from Gällivare in the north to Ystad in the south.

    The study is based on data from more than one million infants born in Sweden between 2012 and 2020. The infants encompassed were born at 34 weeks’ gestation or later. The results are presented in the journal Archives of Disease in Childhood: Fetal & Neonatal Edition.

    Considerable differences

    The study presents the proportion of newborns receiving antibiotics during the first week of life, an internationally dominant metric. In the western world, where sepsis rates are low, the goal is to treat no more than one percent of infants while maintaining low sepsis prevalence and mortality rates.

    In the study, western Sweden ranked highest in antibiotic use, followed by northern Sweden, south-eastern Sweden, southern Sweden, central Sweden, and eastern Sweden. The figures for western Sweden and eastern Sweden were 3.0 percent and 1.3 percent, respectively. Sepsis prevalence in all Swedish regions was below one per thousand live births.

    At hospital level, the lowest antibiotic use of newborns during the first week of life was 0.9 percent, and the highest 4.3 percent.

    One of the driving forces behind the study is Johan Gyllensvärd, a PhD student in pediatrics at Sahlgrenska Academy at the University of Gothenburg and a practicing pediatrician at Ryhov County Hospital in Jönköping.

    “The threshold for antibiotic intervention varies, explained in part by prevalence levels, but it’s also down to local practices. It’s very much a matter of the policies and traditions seen at the different hospitals,” he says.

    Greater awareness key

    Sepsis is a potentially life-threatening condition caused by the immune system’s reaction to an infection. Treatment must be started immediately. At the same time, antibiotics disrupt the bacterial flora, which is sensitive in newborns. Overuse also increases the risk of becoming a carrier of antibiotic-resistant bacteria.

    Antibiotics are essential in the treatment of sepsis in newborns, and if you have a sicker population, then it’s reasonable for antibiotic use to be higher. However, we need to increase awareness of the overuse of antibiotics and improve at distinguishing infected and uninfected infants. This study helps highlight good examples and demonstrates that it’s possible to have a treatment rate of one percent or less of all newborns while maintaining low sepsis and mortality rates.”

    Johan Gyllensvärd, PhD student in pediatrics at Sahlgrenska Academy, University of Gothenburg

    Source:

    Journal reference:

    Gyllensvärd, J., et al. (2025). Variations in antibiotic use in late preterm and term newborns from 2012 to 2020: a nationwide population-based observational study. Archives of Disease in Childhood – Fetal and Neonatal Edition. doi.org/10.1136/archdischild-2025-328944.

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  • Elvis Presley wasn’t fond of ‘Burning Love.’ Then it became a hit.

    Elvis Presley wasn’t fond of ‘Burning Love.’ Then it became a hit.

    By all objective measures, Elvis Presley was a hunk, a hunk of burning love. But he clearly wasn’t feeling it when he heard a demo of “Burning Love” at RCA Hollywood Studios in March 1972.

    The song, a slightly shocking blend of the spiritual and sexual, seemed like a hit to those in the room, with its reverent, raunchy intro:

    Lord Almighty, I feel my temperature rising, mmm.Higher, higher, it’s burning through to my soul.Girl, girl, girl, girl, you’re gonna set me on fire.My brain is flaming, I don’t know which way to go, yeah.

    “Elvis didn’t hate the song, he just wasn’t in the mood for it,” Jerry Schilling, Elvis’ longtime friend who attended the session, tells USA TODAY.

    In the end, Presley reluctantly recorded the gospel-rock track, giving it his high-octane all: “He knew everyone felt that he should do it, he was a reasonable man,” Schilling says. It became Elvis’ final Top 10 hit, peaking at No. 2 on the Billboard Hot 100 that fall.

    “I don’t think Elvis was ever too thrilled about singing lyrics like ‘Flames are now licking my body,’ but he loved having a hit record,” Schilling, 83, writes in the introduction to “Sunset Boulevard,” a new five-disc, 89-track collection that spans Presley’s Los Angeles studio sessions from 1970 to 1975. (Schilling can be glimpsed in the set’s archival images: “I’m very proud to be standing behind Elvis on the cover.”)

    The set includes rare alternate takes − half of which have never been released in the U.S. − rehearsals for his Las Vegas residency, and new stripped-down mixes of classic Elvis cuts, including “For the Good Times,” “Tiger Man,” “T-R-O-U-B-L-E,” “Green, Green Grass of Home,” “Pieces of My Life,” “Memories” and “Softly As I Leave You.”

    “I’m kind of a purist, you know: Don’t mess with Michelangelo’s paintings or change the clouds. Don’t mess with the artist,” says Schilling, talking from his home in California, which Elvis gifted him in 1974. “There’s a tremendous responsibility. When the big questions come up, I go, what would I do if Elvis was sitting next to me? That’s how I judge it. I know my friend.”

    The singer never shied away from the provocation of songs like “Burning Love,” Schilling adds. But in the early ‘70s, as Elvis privately struggled with his disintegrating marriage to Priscilla Presley, he gravitated toward expressions of heartbreak and regret such as the autobiographical “Separate Ways” and “Always on My Mind” (both included in the set).

    Over time, he came to embrace the lusty song as part of his live repertoire, breaking it out months later for an epic “Aloha From Hawaii” performance.

    “There’s a part of Elvis that wanted to be sexy,” Schilling says. “And there’s a part of him that wanted to be a great gospel singer.”

    In “Burning Love,” he got to be both.

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  • IATA: Air demand slowed in June amid Middle East conflict

    IATA: Air demand slowed in June amid Middle East conflict

    Global air passenger traffic demand in June grew at its lowest rate since March with just a 2.6 per cent year-on-year increase in revenue passenger kilometres (RPKs), according to the latest figures from airline association IATA.

    IATA pointed to conflict in the Middle East as a key driver in the lower demand – many carriers were forced to cancel or reroute flights in June following Israeli airstrikes on Iran and the subsequent 12-day conflict between the two nations.

    Willie Walsh, the association’s director general, said: “That’s a slower pace than we have seen in previous months and reflects disruptions around military conflict in the Middle East.”

    Total global capacity in June, as measured in available seat kilometres (ASKs), increased by 3.4 per cent year-on-year, and global load factor declined 0.6 percentage points for the month to 84.5 per cent. Monthly international demand increased by 3.2 per cent year-on-year globally, while capacity was up by 4.2 per cent.

    Regional figures show that airline passenger traffic in Europe rose by 2.2 per cent year-on-year in June, with capacity up by 2.6 per cent for the month. This led to a slight drop in load factor of 0.3 percentage points to 87.8 per cent in June, which was still the highest level of any global region.

    “At 84.5 per cent globally, however, load factors are still very strong,” added Walsh. “And with a modest 1.8 per cent capacity growth visible in August schedules, load factors over the Northern summer are unlikely to stray far from their recent historic highs.”

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  • Opposition alliance urges CJP to act on Rs300bn sugar scandal

    Opposition alliance urges CJP to act on Rs300bn sugar scandal

    The Tehreek Tahaffuz-e-Ain has written to Chief Justice of Pakistan (CJP) Yahya Afridi, urging him to take suo motu notice of an alleged sugar industry scandal in which mills reportedly profited by Rs300 billion due to recent price fluctuations.

    In a letter addressed to the CJP, Vice Chairman Mustafa Nawaz Khokhar called for the formation of a commission under Article 184(3) of the Constitution to investigate suspected policy manipulation and regulatory failures.

    Khokhar requested that the issue be urgently referred to a three-member committee or that the letter be treated as a formal petition to initiate judicial proceedings.

    “The future of the country’s economic stability and citizens’ trust in governance hinges on prompt and decisive action,” the letter added.

    It further highlighted that the Public Accounts Committee was informed on Tuesday, July 29, that sugar mills had earned Rs300 billion through recent rate hikes.

    CCP reschedules hearing

    The Competition Commission of Pakistan (CCP) has postponed the hearing of the sugar cartel case after over 70 sugar mills requested a delay, citing the unavailability of legal counsel due to the Supreme Court’s summer recess.

    In a statement issued on Monday, the CCP announced that the hearing will now take place from September 22 to 25. The decision follows multiple adjournment pleas submitted by sugar mills.

    More than 50 mills have also filed appeals in the Supreme Court challenging the tribunal’s decision directing the CCP to rehear the case.

    The commission clarified that the hearing has been deferred once to fulfil the requirements of a fair trial. However, it emphasised that no further delay or adjournment would be granted.

    The CCP stated that the case proceedings will be conducted daily.

    Read: CCP to hear sugar pricing case today

    Earlier in May, the Competition Appellate Tribunal had returned the case to the CCP for rehearing after announcing its verdict on the appeals filed by the sugar mills and the association against a Rs44b fine.

    The tribunal instructed that the case be reheard under the supervision of the CCP chairperson or any other member who was not previously involved in the hearings.

    The tribunal also ordered the commission to complete the rehearing and issue a verdict within 90 days.

    In 2021, the CCP imposed a Rs44 billion fine on the PSMA and its member mills for forming a cartel to fix sugar prices and engaging in other anti-competitive practices.

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  • Independent disciplinary process update: Dan Sheehan (British and Irish Lions) – World Rugby

    Independent disciplinary process update: Dan Sheehan (British and Irish Lions) – World Rugby

    1. Independent disciplinary process update: Dan Sheehan (British and Irish Lions)  World Rugby
    2. Australia’s Tom Lynagh ruled out of third Test against Lions after brutal elbow  The Independent
    3. Independent Disciplinary Update: Dan Sheehan (British & Irish Lions)  World Rugby
    4. Lions hooker Sheehan cited for dangerous Lynagh cleanout  RUGBY.com.au
    5. ‘Just absurd’: Wallabies fans fume over missed Tom Lynagh act as TMO drama baffles  Yahoo Home

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  • James Norton’s King & Conqueror Set For Prime Video & HBO Max

    James Norton’s King & Conqueror Set For Prime Video & HBO Max

    EXCLUSIVE: James Norton and Nikolaj Coster-Waldau‘s King & Conqueror will play on Prime Video in the U.S. and HBO Max in a slew of territories after Paramount Global sealed a raft of deals for the soon-to-launch historical epic.

    The drama stars Norton as Harold, Earl of Wessex, opposite Coster-Waldau as William, Duke of Normandy, two men destined to clash at the Battle of Hastings. Emily Beecham plays Edith Swan-neck and Clémence Poésy stars as Matilda, their respective wives. The drama tells the story of the people, dynasties and events that went on to shape history.

    The series is produced by Rabbit Track Pictures, the label that Norton runs with Kitty Kaletsky, alongside The Development Partnership, Shepherd Content, RVK Studios and CBS Studios, in association with the BBC, which has the UK rights and launches the show later this month. The first trailer dropped last week.

    Paramount Global Content Distribution is across sales and has racked up deals spanning over 100 territories. Prime Video has taken it for the U.S. and HBO Max will show the 1066 drama in the Nordics, Iberia, Southeast Asia, the Netherlands, Hong Kong, and Taiwan.

    PGCD held a packed buyers-only screening for King & Conqueror – the opening episode of which is directed by Baltasar Kormákur – at the London Screenings in February.

    It clearly struck a chord with the assembled acquisitions folk. SBS has acquired it for Australia and JioHotstar for India. It has also sold to buyers including Showcase and StackTV (Canada), M-Net (Africa), Streamz and Be TV (Belgium), Cosmote TV (Greece), Yes and Hot (Israel), Sky NZ (New Zealand), and LRT (Lithuania).

    The deals come ahead of a glitzy London premiere for the series, next week.

    King & Conqueror is a sweeping, cinematic drama with global appeal, and we’re thrilled to see such strong demand from leading platforms around the world,” says Lisa Kramer, President of International Content Licensing at PGCD. “Compelling storytelling, exceptional cast, and bold creative vision make it a standout series that resonates across markets and cultures.”

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  • FAQs and how to watch the action live

    FAQs and how to watch the action live

    How and where to watch The World Games 2025 Chengdu live?

    Select action from The World Games 2025 Chengdu will be available to stream live on Olympic Channel via Olympics.com with territorial restrictions in place.

    The sports of Cheerleading, Flying Disc, Powerlifting, Flag Football, Lacrosse, Squash, Softball (Finals), Gymnastics (including Parkour), Roller Sports, Breaking (Finals) and Sport Climbing will be available to watch live in Brazil, France, UK, Germany, Spain, Republic of Korea, Indonesia, Egypt, and South Africa.

    In Japan, the following sports will be streaming: Cheerleading, Flying Disc, Powerlifting, Squash, Gymnastics (including Parkour), Roller Sports, Breaking (Finals) and Sport Climbing.

    World Games action will also be available to watch live in India, with restrictions still to be announced.

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  • 4 Taylor Swift-Inspired Business Tips CEOs Can Take From the Billionaire

    4 Taylor Swift-Inspired Business Tips CEOs Can Take From the Billionaire

    Taylor Swift is not only a beloved musical artist with an ever-growing catalogue of innately singable songs; the billionaire pop star is increasingly the preeminent example of a powerhouse business strategist forging a new path for those who seek to steal market share and run the game their way.

    The mega star’s business acumen is the subject of Sinéad O’Sullivan’s forthcoming book, “Good Ideas and Power Moves: Ten Lessons for Success from Taylor Swift.” O’Sullivan, a defense economist, investor, and writer, used her own business expertise to analyze Swift’s career.

    As O’Sullivan navigated her own high-powered career with stints at the Department of Defense and NASA, the Harvard Business School alum and self-proclaimed “massive Swiftie” told Business Insider that she couldn’t get Swift’s singular road map out of her head.

    “Anytime I thought about her, I thought about how what we’re teaching at business school no longer resonates with what she is doing,” O’Sullivan said in a June interview. “I started to think less about what Warren Buffett would do, and more about what Taylor would do.”

    “Good Ideas and Power Moves” is the culmination of more than a decade’s worth of O’Sullivan’s obsession with Swift, she told Business Insider. “It was all in my head already, so the book only took me six weeks to write.” In it, O’Sullivan unpacks 10 of Swift’s unique power moves that anyone from Fortune 500 CEOs to small-time retailers can emulate to build their base and top the charts.

    Here is a sample of some of the tips O’Sullivan explores in her book, which is out September 9.

    Build power laterally — not from the top down

    Much of Swift’s massive cultural power comes from her fiercely loyal and ever-expanding fan base. The Swifties, as her fans are known, have played a major role in the singer’s ability to maintain relevance for more than a decade amid a rapidly shifting music industry. From shelling out thousands for Eras Tour tickets to exclusively listening to the singer’s re-recordings (and shaming anyone who refuses to do the same), Swifties are among the most zealous fans operating today.

    Unlike traditional business structures, where power and control flow from executives at the top down to employees at the bottom, Swift’s power moves laterally, O’Sullivan said.

    The singer has emphasized her own relatability and nurtured her relationship with her dedicated devotees to create a fanbase that feels as though Swift is one of them, the author told Business Insider.

    “She has enabled an entire group of people not by being above them, but by being one of them,” O’Sullivan said. “A lot of the time, she’s not even in the room, and her fans move without her.”

    When one of Swift’s Eras Tour shows was canceled in Vienna in August 2024, her fans organized impromptu gatherings where they sang her songs, exchanged friendship bracelets, and recreated the concert experience — all without any guidance or direction from the singer herself.

    Wielding her power horizontally has allowed Swift to scale very quickly, O’Sullivan said, citing the singer’s “peer-to-peer currency.”

    “She no longer even needs to be present for her power to increase,” O’Sullivan said. “Her fans feel like she is always there, but what they actually are experiencing is having other Swifties around.”

    Be antifragile

    Swift has managed to catapult herself to unmatched levels of power amid a particularly unpredictable moment in business.

    “We live in a weird time. Everything feels like it no longer fits our models,” O’Sullivan said. “The rules have kind of stopped following the traditional, long-held patterns.”

    Uncertain times, however, present a unique opportunity for those who have figured out how to get stronger, not weaker, in moments of adversity. After nearly two decades in the music industry, Swift has mastered antifragility, jumping in popularity and sales at moments where other singers have fallen, O’Sullivan said.

    Take the pandemic, for example. COVID lockdowns curtailed artists’ abilities to do their jobs as tours were put on hold, studios shut down, and promotion took a back seat.

    But where others saw a closed door, Swift saw an opportunity. With people sitting at home under lockdown, the singer understood people needed more content, not less. And because she owns her entire supply chain — an in-house recording studio, strong relationships with other musicians, and the ability to go direct-to-consumer — she was able to give the people what they needed during a difficult time. In July 2020, at the height of the pandemic, the singer released “folklore,” which became the best-selling album of the year.

    “When others find difficulties in the system breaking down, that’s when Swift is able to get in and win big,” O’Sullivan said. “Every time something ‘bad’ happens to her, she is actually able to use it to make big leaps in her career and steal market share.”

    Negotiate with authenticity

    From the moment she burst on the scene at 16 years old, Swift’s superpower has always been her authenticity, O’Sullivan said.

    “In the world of business and finance, it’s uncommon to have unwavering beliefs and such a strong sense of self,” the author said. “People tend to shift quite quickly depending on the markets or who is in power.”

    Not Swift, according to O’Sullivan.

    Sure, the singer initially gained popularity by singing about romance and relationships, but as she moved into her older teens — a time when the music industry typically forces female performers into sex-centered stereotypical roles — Swift removed herself from that equation and doubled down on her real self.

    Authenticity is especially important for Swift because the product she’s selling is herself, O’Sullivan said; any hint of phoniness or fraud in the superstar’s marketing would be immediately obvious to her dedicated fans who feel like they personally know the singer thanks to her confessional lyrics.

    Swift’s reverence for her own deep feelings and emotionality — traits that are traditionally scorned in the male-dominated business world — have actually given her significant leverage among her primarily female fan base, O’Sullivan said.

    “She’s just a great example of doing things in a totally different way,” the author said.

    Don’t eat the marshmallow

    That Swift’s profile is as massive as it is, nearly two decades into her career, is proof enough that she’s something special, O’Sullivan said. The music industry, like so many others operating under capitalism’s quarter-to-quarter earnings system, churns out performers and products at a rate meant to capitalize on novelty and the next big thing.

    Swift’s long-game mindset has garnered her longevity and legacy in a world where so many others have achieved only immediate validation, O’Sullivan said.

    “Good things take time and patience,” she said. “Real success often requires you to forgo early wins.”

    Instead of chowing down on the proverbial marshmallow as soon as it’s been roasted, Swift has built an empire on taking her time to create the perfect s’more.

    “If you’re a CEO, you probably feel that pressure every minute,” O’Sullivan said. “But it’s about having a long-term strategy so you don’t have to just take the next thing coming.”


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  • New ancient marine reptile species discovered in Germany’s famous Jurassic fossil beds

    New ancient marine reptile species discovered in Germany’s famous Jurassic fossil beds

    image: 

    Plesionectes longicollum 


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    Credit: Credit Artist: Peter Nickolaus

    Paleontologists have identified a new species of ancient marine reptile from Germany’s world-renowned Posidonia Shale fossil beds, expanding our understanding of prehistoric ocean ecosystems that existed nearly 183 million years ago.

    The newly classified species, named Plesionectes longicollum (“long-necked near-swimmer”), represents a previously unknown type of plesiosauroid—the group of long-necked marine reptiles that inhabited Earth’s oceans during the age of dinosaurs. The specimen is a nearly complete skeleton that even preserves remnants of fossilised soft tissue. It was originally excavated in 1978 from a quarry in Holzmaden, Southwest Germany, but its unique anatomical features have only now been fully recognized through comprehensive scientific analysis.

    “This specimen has been in collections for decades, but previous studies never fully explored its distinctive anatomy,” said Sven Sachs of the Naturkunde-Museum Bielefeld, the study’s lead author. “Our detailed examination revealed an unusual combination of skeletal features that clearly distinguish it from all previously known plesiosaurs.”

    The research, published by Sven Sachs and co-author Dr. Daniel Madzia from the Polish Academy of Sciences, demonstrates that the Posidonia Shale—already famous for its exceptionally preserved fossils—contained even greater marine reptile diversity than previously recognized.

    The Plesionectes specimen is particularly significant as it represents the oldest known plesiosaur from the Holzmaden area. Despite being an immature individual, its distinctive anatomical characteristics were not significantly affected by its developmental stage, warranting classification as an entirely new genus and species.

    “This discovery adds another piece to the puzzle of marine ecosystem evolution during a critical time in Earth’s history,” explained Dr. Madzia. “The early Toarcian period when this animal lived was marked by significant environmental changes, including a major oceanic anoxic event that affected marine life worldwide.”

    The fossil is permanently housed at the Staatliches Museum für Naturkunde Stuttgart (Stuttgart State Museum of Natural History) where it is cataloged as specimen SMNS 51945.

    The Posidonia Shale at Holzmaden has previously yielded five other plesiosaur species, including representatives from all three major plesiosaur lineages. This new addition further cements the formation’s status as one of the world’s most important windows into Jurassic marine life.

    Read the full article in PeerJ Life & Environment https://peerj.com/articles/19665/ (please note this link will only work from 4th August.)

    Watch a video interview with author https://youtu.be/C3J0YAk4WEc


    Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.

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  • What’s Inside the Tiny Miracle Food Pouches That Can Save the Lives of Starving Gazans

    What’s Inside the Tiny Miracle Food Pouches That Can Save the Lives of Starving Gazans

    Take a peanut-based paste packed with 500 calories and nearly 13 grams of protein. Store it in a 92-gram foil pouch, so it can be easily sucked by starving infants on the front line. No water or refrigeration is required, meaning it can be distributed in drought-hit areas and stored at ambient temperature for up to two years. Just a couple of daily sachets can lead to a 10 percent weight gain over six weeks, sustaining recovery from severe acute malnutrition for less than $60 per child. Saving a life, it turns out, literally costs peanuts: just 71 cents a serving.

    This life-saving mixture is Plumpy’Nut. Developed by Normandy-based manufacturer Nutriset in 1996 by French paediatrician André Briend, it was the first ready-to-use therapeutic food (RUTF): energy-dense pastes that have boosted survival rates of severe acute malnutrition in children from less than 25 per cent to around 90 percent.

    The paste has saved tens of millions of lives. “It’s incredibly effective emergency food,” says medical doctor Steve Collins, founder of advocacy group Valid Nutrition. “RUTF contains all the essential nutrients required for someone to recover from severe acute malnutrition. They’re easy to transport, extremely energy dense, and don’t require a cold supply chain or clean water to work.”

    While Nutriset’s product was the first RUTF to be developed, it is not the only brand in this important field. Mana, for example, is an American-made RUTF produced in Fitzgerald, Georgia. The company states it can make 500,000 pounds of product per day—enough to fill four shipping containers, and feed 10 million children per year.

    Before Plumpy’Nut, cases of severe acute malnutrition—primarily occurring among children under 5 years old, diagnosed by very low weight-for-height scores and arm circumference—needed round-the-clock care at therapeutic feeding centres. Nurses at these makeshift hospitals in often remote areas would feed infants F100, a high-energy milk powder also made by Nutriset. Bacteria was often rife. “There was always a risk that water was contaminated and carried disease,” says Collins. It’s one of the reasons why mortality rates for in-patient care lurked at around 20 percent.

    Over half of Plumpy’Nut is made from peanut paste and vegetable oils. The nutty primary base contains fat-soluble nutrients, as well as protein, energy, and fatty acids that spark recovery. Nearly a quarter is skimmed milk powder, containing dairy protein and essential amino acids, the building blocks of protein. Another quarter is reserved for sugar—masking the taste of the added micronutrients: potassium, magnesium, calcium, iron, zinc, iodine, copper, selenium, and vitamins A, D, E, B complex, C, and K.

    The apocryphal story is that Briend’s idea for the marvel that is Plumpy’Nut came from a jar of Nutella. In reality, it came from firsthand experience on the front line in the Sahel: The water-based solution wasn’t working—infants were still dying. Working with Nutriset founder Michel Lescanne, his idea was to add F100 to a spread of peanuts (a common crop in areas of malnutrition and a natural protein-rich source) with oil and sugar.

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