Blog

  • Pakistan’s 2025 polio tally surges to 26 with two new cases

    Pakistan’s 2025 polio tally surges to 26 with two new cases



    A health worker administers polio drops to a child on the first day of a nationwide polio vaccination campaign, in Karachi on February 3, 2025. — AFP 

    ISLAMABAD: Two fresh polio cases have been confirmed in Khyber Pakhtunkhwa, bringing Pakistan’s total count this year to 26, the Regional Reference Laboratory for Polio Eradication at the National Institute of Health (NIH) said on Monday.

    The laboratory said the latest cases involve a 19-month-old girl from Union Council Mir Ali in District North Waziristan and an 11-month-old girl from Union Council Suleman Khel in District Lakki Marwat.

    With these detections, Khyber Pakhtunkhwa accounts for 18 of the total reported cases this year, followed by Sindh with six, and one each in Punjab and Gilgit-Baltistan, the regional laboratory added.

    Polio is a highly infectious and incurable disease that can cause lifelong paralysis. The only effective protection is through repeated doses of the Oral Polio Vaccine (OPV) for every child under five during each campaign, alongside timely completion of all routine immunisations.

    Despite significant progress, the continued detection of polio cases, particularly in southern KP, remains a serious concern. It underscores that children in hard-to-access areas and those with low vaccine acceptance continue to be at risk.

    Meanwhile, Pakistan’s polio surveillance system tested 126 environmental samples from 87 districts during August. Of these, 75 samples were declared negative while 51 tested positive for poliovirus.

    Sindh recorded the highest proportion of positive samples with 24, followed by Punjab with 14, Khyber Pakhtunkhwa with 10, and one each in Balochistan, Gilgit-Baltistan, and Islamabad. Encouragingly, Balochistan showed a marked reduction in positive sites, down from 19 in January to just one in August, the regional laboratory added.

    Last month, two new cases of poliovirus were confirmed from south Khyber Pakhtunkhwa — one from district Tank and the other from district North Waziristan.

    The cases included a 16-month-old girl from Union Council Mullazai, District Tank, and a 24-month-old girl from Union Council Miran Shah-3, District North Waziristan. 

    Continue Reading

  • Vietnam’s capital reports rising dengue fever cases-Xinhua

    HANOI, Sept. 15 (Xinhua) — Vietnam’s capital Hanoi has reported a rise in dengue fever cases, with new hotspots emerging, Vietnam News Agency reported Monday.

    The city recorded 150 cases from Aug. 22 to 28, rising to 161 cases from Aug. 29 to Sept. 5 and 190 cases from Sept. 6 to 12, according to the Hanoi Center for Disease Control.

    Since the beginning of this year, 72 hotspots have been identified in the city, of which 22 remained active.

    The number of cases was forecast to continue to rise in line with the annual epidemic cycle, the report said.

    The center will integrate Chikungunya prevention into dengue control campaigns, including eliminating mosquito larvae and pupae and chemical spraying in high-risk areas.

    Continue Reading

  • Easy-to-use robot intubation tool could save lives

    Easy-to-use robot intubation tool could save lives



    A new soft robot intubation device could save lives.

    The innovative tool, designed specifically for non-expert users, improves airway access and raises survival odds in critical medical emergencies

    Maintaining an open airway is a critical priority in emergency medicine. Without the flow of oxygen, other emergency interventions can become ineffective at saving the patient’s life.

    However, creating this airway through endotracheal intubation is a difficult task for highly trained individuals and under the best of circumstances.

    In the field and in the ER, where seconds matter, emergency medical personnel face many unknowns and wildly challenging conditions which lower their chances of success.

    But what if successful endotracheal intubation could be less reliant on ideal conditions and years of specialized training?

    In a paper in the journal Science Translational Medicine, University of California, Santa Barbara researchers David Haggerty, Elliot Hawkes, and collaborators demonstrate a nonelectronic soft robotic device that quickly and autonomously guides a soft tube into the trachea.

    Initial device testing with highly trained users yielded a 100% success rate, and a 96% overall success rate with prehospital medical providers (EMTs and paramedics).

    “Current intubation tools require extensive anatomical knowledge, training, skill, and ideal conditions to be highly successful,” says recent UC Santa Barbara PhD graduate David Haggerty, a former researcher in the lab of mechanical engineering professor Elliot Hawkes.

    Current technology calls for the rescuer to first visualize the tracheal opening then manually direct a tube through the serpentine anatomy of the airway into the trachea. The challenge of this procedure increases in prehospital settings due to various factors including inadequate light and nonideal body position in addition to potential injuries and fluid in the airway.

    One of the main challenges to successful intubation is the body itself, and the mechanisms it has evolved to prevent food and foreign bodies from entering the lungs. The epiglottis is a small fleshy flap that closes over the trachea and guides food and liquid into the adjacent esophagus with each swallow. Conventional practice typically requires the rescuer to push a metal laryngoscope into the back of the mouth behind the tongue to lift the epiglottis out of the way in order to make room for the breathing tube.

    But even with the epiglottis out of the way, the path the endotracheal tube must take is a twisted one, as it has to bend toward the front of the neck where the trachea is located, otherwise air could be delivered to the stomach via the esophagus, instead of to the lungs.

    “Traditional tools, which you push from the base, are fundamentally limited in navigating delicate, tortuous anatomy,” Hawkes explains.

    “They must be relatively stiff so you can push them, and can only get around bends by deflecting off the sensitive tissue.”

    The researchers’ device upends that paradigm with a soft, inflatable tube that everts from its tip. Called the soft robotic intubation system (SRIS), it consists of a curved “introducer” that slides into place at the back of the throat and stops at the esophagus. With that in place, a soft, pre-inflated tube is threaded through the introducer, emerging near its tip at the opening of the trachea. As the user advances the tube, it everts from its tip, carrying inside it a soft breathing tube as it enters the trachea.

    “So instead of trying to push this tube and bend it to get into this complex configuration, we can just mechanically create that complex configuration as we go,” Haggerty says. Once the endotracheal tube is at its destination, the user can inflate a cuff at its distal end to seal the opening and begin ventilation. The introducer can be removed, leaving the breathing tube in place.

    Introducing a soft, growing tube eliminates friction with the surrounding tissue and minimizes injury due to excessive or misplaced force. It also automatically conforms to its environment, one of the major benefits of soft robotics.

    “This growing paradigm naturally accounts for minor variations in anatomical placement, size, shape or configuration,” Haggerty says, and because of this, users need not have extensive skill or a perfect understanding of the environment in order to navigate it.

    In tests with mannequins and cadavers, the SRIS proved itself both effective, and, importantly, rapid, with a 100% success rate at a procedure duration of just seconds for expert users. For nonexpert users—the primary target of this technology—a five-minute training session was all that was needed to deliver an 87% success rate for first-pass attempts, translating into an 96% overall success rate, with a significantly lower procedure duration—21 seconds versus 44 seconds—than state-of-the-art video laryngoscope intubation.

    The next step for the researchers is to conduct clinical trials in order to get approvals from the Food and Drug Administration for clinical use.

    “We have good reason to believe it’s efficacious based on the data, but cadavers don’t say ‘ow’,” Haggerty says.

    They need to complete more testing to ascertain the device’s safety and effectiveness in a variety of airways and external conditions, he added. If successful, this device could benefit the millions of emergency intubations that occur each year in the US, and find application in military medical care. That’s in addition to its potential to save lives in global populations that have poor or no access to essential health services.

    Additional collaborators on this work are from UC Santa Barbara; Vine Medical, Inc.; Whatcom County Emergency Medical Services in Washington; University of Texas Health; the Fort Worth Office of the Medical Director; Stanford University; and University of Pittsburgh Medical Center.

    Support for this project came, in part, from funds from the National Science Foundation

    Source: UC Santa Barbara

    Continue Reading

  • Romosozumab outperforms teriparatide and denosumab in bone strength

    Romosozumab outperforms teriparatide and denosumab in bone strength

    Romosozumab outperforms teriparatide and denosumab in bone strength | Image Credit: © RFBSIP – © RFBSIP – stock.adobe.com.

    A recent clinical study presented by Koji Ishikawa, MD, PhD, orthopedic spine surgeon at Duke University, and Tony M. Keaveny, PhD, Founder and Chief Science Officer of O.N. Diagnostics, compared the effects of romosozumab, teriparatide, and denosumab on bone strength in patients with osteoporosis.

    The analysis focused on the hip and spine, where fracture risk is particularly great. Results showed that romosozumab provided substantially greater improvements in bone strength after 1 year of treatment compared to the other 2 drugs. At the spine, for example, romosozumab increased bone density by approximately 25% but boosted bone strength by about 40%, highlighting that strength gains are not fully reflected by bone density measurements from standard DXA scans.

    The findings are significant because fracture prevention depends more on improved breaking strength than on density alone. Data from real-world clinical care also suggest even greater percentage gains than those seen in earlier phase-2 and phase-3 trials.

    Notably, romosozumab demonstrated the unique ability to transform highly osteoporotic vertebrae into bones at much lower risk of biomechanical failure, as shown through virtual stress testing models. According to the researchers, romosozumab stands out as the most effective treatment for strengthening both hip and spine bones, offering a compelling advantage over teriparatide and denosumab.

    Contemporary OB/GYN:

    Please provide an overview of your presentation about bone strength from romosozumab vs teriparatide or denosumab.

    Koji Ishikawa, MD, PhD & Tony M. Keaveny, PhD:

    This study compared the breaking strength of the hip and spine bones for different osteoporosis drug treatments and showed that the strength benefits after 1 year of treatment were substantially greater for romosozumab compared to both teriparatide and denosumab.

    Contemporary OB/GYN:

    What is the significance of these findings?

    Ishikawa & Keaveny:

    Changes in bone density as measured by clinical-standard DXA testing are difficult to interpret because what matters most in terms of fracture reduction is how much the breaking strength changes. This study is significant because it demonstrates the substantial benefits for breaking strength – more than for bone density. For example, at the spine, romosozumab increased bone density by about 25% but bone strength by about 40%. So, the benefits of the treatment are underestimated when measured by bone density. And of course, those benefits were greater for romosozumab than either of the other 2 treatments.

    Contemporary OB/GYN:

    What were the main takeaways of your presentation?

    Ishikawa & Keaveny:

    As we have seen in other clinical trials, romosozumab is the better treatment in terms of its bone-strengthening benefits, both at the hip and spine. Here we have data from actual clinical care.

    Contemporary OB/GYN:

    What other research about the impact of romosozumab on bone strength would you like to highlight?

    Ishikawa & Keaveny:

    These results suggest even greater gains, percentage-wise at least, for these highly osteoporotic and treatment-naïve patients from clinical care than what we observed in a prior phase-2 BCT study in women with low bone mass (Keaveny JBMR 2017) and also in a phase-3 imaging substudy of osteoporotic women with prior bisphosphonate therapy (Langdahl Lancet 2017).

    Contemporary OB/GYN:

    Is there anything you would like to add?

    Ishikawa & Keaveny:

    These results are particularly compelling at the spine for romosozumab because the drug benefit is so large — it takes a highly osteoporotic bone and transforms it into one at much lower risk of biomechanical failure. This is seen visually with the virtual stress testing. Here, virtual forces are placed on the bone that would normally fracture and crush an osteoporotic bone. After treatment with romosozumab, that same level of force produces almost no damage in the bone. Romosozumab appears to be the only drug treatment that can transform the osteoporotic vertebra in this way.

    Continue Reading

  • Early Release – Zoonotic Soil-Transmitted Helminth Infections among Humans, Gabon – Volume 31, Number 10—October 2025 – Emerging Infectious Diseases journal

    Early Release – Zoonotic Soil-Transmitted Helminth Infections among Humans, Gabon – Volume 31, Number 10—October 2025 – Emerging Infectious Diseases journal

    Disclaimer: Early release articles are not considered as final versions. Any changes will be reflected in the online version in the month the article is officially released.


    Author affiliation: James Cook University, Townsville, Queensland, Australia (H. Zhao, R.S. Bradbury); National Centre for Naturopathic Medicine, Southern Cross University, Lismore, New South Wales, Australia (P.N. Mutombo); Centres for Disease Control and Prevention, Addis Ababa, Ethiopia (P.N. Mutombo); National Centre for Scientific and Technological Research of Gabon, Libreville, Gabon (R. Mintsa-Nguema); Programme National de Lutte contre les Maladies Parasitaires, Ministère de la Santé, Libreville (D. Nkoghe, J. Atsame); Westmead Hospital, Westmead, New South Wales, Australia (M. Watts); University of Sydney, Sydney, New South Wales, Australia (M. Watts); University of Queensland, Brisbane, Queensland, Australia (C. Gordon); QIMR Berghofer Medical Research Institute, Brisbane (C. Gordon)

    Deforestation and environmental degradation across Central Africa, including Gabon, have increasingly brought nonhuman primates (NHPs) close to human settlements. In forest-edge communities, bushmeat hunting and forest resource exploitation further intensify human–NHP interactions (1). Those interactions increase the risk for zoonotic parasitic infections from NHP reservoirs to humans, including infections with soil-transmitted helminths (STHs) (1,2).

    In reports from Europe, researchers were infected with Necator gorillae hookworms (3,4) and Strongyloides fuelleborni fuelleborni threadworms (5) during fieldwork with NHPs in Central Africa, suggesting that zoonotic STH infections might occur extensively in human communities near NHP habitats. A subsequent study among villagers living near NHP habitats in Gabon identified 2 additional human N. gorillae infections on the basis of internal transcribed spacer (ITS) 1 and 2 haplotyping analysis (6). To determine the extent of zoonotic STH infections in human populations, we conducted a survey of stool samples from villagers in Gabon.

    We conducted a parasitologic survey of 226 human stool samples in July 2023, during the dry season in Ngounié Province, Gabon. We collected samples from persons in 6 forest-edge communities situated within a tropical savanna climate zone (Köppen classification Aw) (Appendix Figure 1).

    Figure 1

    Figure 1. Light microscopy images of soil-transmitted helminths from human stool samples, Gabon. A, B) Hookworm eggs; scale bars indicate 25 µm. C) Strongyloidesspp. eggs; scale bar indicates 25 µm….

    Upon collection, we preserved stool specimens in 10% formalin and 70% ethanol and shipped them to Australia for analysis. Using formalin ethyl acetate sedimentation microscopy (7), we identified hookworm eggs in 15 samples, S. f. fuelleborni roundworm eggs in 6 samples, and Strongyloides spp. roundworm larvae in 1 sample (Figure 1). A total of 20 samples were helminth-positive, and some involved co-infections (Appendix Table 1).

    We performed metabarcoding on DNA extracts from those 20 samples by targeting the mitochondrial cytochrome c oxidase subunit I (cox1) gene and the hypervariable region IV (HVR-IV) of 18S rDNA, 2 well-established genetic markers for helminth species identification (8). We targeted a 217-bp region of cox1 to identify helminth species (8). Then, to further characterize Strongyloides species and genotypes, we conducted a second metabarcoding assay targeting 18S rDNA HVR-IV (≈255 bp) (8) on the 7 Strongyloides spp.–positive samples. For both assays, we performed sequencing on a MiSeq platform by using MiSeq Reagent Nano Kit v2 (both Illumina, https://www.illumina.com) and 500 cycles for 250-bp paired-end reads. We used Geneious Prime version 2024.0.4 (https://www.geneious.com) to analyze sequence data, then used a custom workflow incorporating read quality control, contig assembly, and haplotype assignment. We conducted phylogenetic analyses of MUSCLE-aligned (https://www.ebi.ac.uk/Tools/msa/muscle) cox1 sequences by using maximum-likelihood (MEGA 11, https://www.megasoftware.net) and Bayesian inference (MrBayes, https://github.com/NBISweden/MrBayes) methods and applying the general time-reversible nucleotide substitution model.

    Eighteen of the 20 samples yielded cox1 amplicons. Upon sequencing, 3 samples were dominated by reads from co-infecting Ascaris lumbricoides roundworms, but we did not detect sequences for hookworms or Strongyloides spp. roundworms. The other 15 samples yielded sequences assigned to Necator spp. (n = 11), S. f. fuelleborni (n = 3), or Ancylostoma spp. (n = 1) helminths (Appendix Table 1). Among the 11 Necator spp.–positive samples, 10 harbored Necator americanus hookworms, and 4 contained a Necator sp. hookworm with cox1 sequences that had 100% identity to GenBank accession no. AB793562, a species previously detected in researchers from Europe who were infected in the Central African Republic (CAR); that species was later morphologically identified as N. gorillae (3). Three of the 4 N. gorillae–positive samples had N. americanus co-infection (Appendix Table 1).

    Figure 2

    Maximum-likelihood phylogeny of zoonotic soil-transmitted helminths from human infections, Gabon. A) Necator spp. hookworms; color-coded groups are labeled per nomenclature by Hasegawa et al. (4). B) Strongyloides fuelleborni fulleborni threadworms; color-coded groups represent geographic regions. Trees are based on cox1 sequences and were created by using MEGA 11 (https://www.megasoftware.net) and Bayesian inference using MrBayes (https://github.com/NBISweden/MrBayes). Bayesian posterior probability and maximum-likelihood bootstrap support percentages (1,000 bootstrap replicates) are indicated at the nodes. Bold font and black circles indicate sequences obtained in this study. Published sequences are annotated with the country of origin, host species, and GenBank accession numbers. Scale bars indicate nucleotide substitutions per site. CAR, Central African Republic

    Figure 2. Maximum-likelihood phylogeny of zoonotic soil-transmitted helminths from human infections, Gabon. A) Necator spp. hookworms; color-coded groups are labeled per nomenclature by Hasegawa et al. (4). B) …

    Analysis of cox1 sequence data revealed 15 haplotypes of N. americanus and 2 of N. gorillae. Maximum-likelihood and Bayesian inference phylogenetic analyses placed N. americanus sequences (217-bp) from this study within a clade containing previously published sequences for that species (Figure 2, panel A). The N. gorillae sequences clustered with isolates from NHPs from CAR and Gabon and with isolates recovered from the infected researchers from Europe (Figure 2, panel A). We also detected 1 cryptic Ancylostoma sp. hookworm that we could not confidently assign to any known species based on available data. At the cox1 locus, that Ancylostoma sp. hookworm clustered basally to Ancylostoma caninum (GenBank accession no. AP017673) and another unidentified Ancylostoma sp. hookworm (GenBank accession no. MK434228) identified in dogs from Australia (Figure 2, panel A). We identified 4 cox1 haplotypes of S. f. fuelleborni roundworms, all of which fell within the African clade of that species (Figure 2, panel B). An attempt to sequence the cox1 of the S. stercoralis–positive sample was unsuccessful.

    We obtained 18S rDNA HVR-IV sequences of 255–258-bp length from 6 Strongyloides-positive samples; we identified 5 as S. f. fuelleborni and 1 as S. stercoralis (Appendix Table 1). Haplotyping analysis assigned the S. stercoralis–positive sample to HVR-IV haplotype A, previously found in humans, dogs, cats, and NHPs (8,9). S. f. fuelleborni–positive samples harbored haplotypes K, L, O, or a combination thereof, previous found in NHPs from Africa and humans (10,11) (Appendix Figure 2).

    Among sampled communities in Gabon, we found one third (4/12) of hookworm infections were attributable to N. gorilla. Multiple N. gorillae cox1 haplotypes suggest several separate infection events and might be related to higher exposure in certain occupations or other factors, but those data were not available.

    Human Necator spp. hookworm infections other than N. americanus were previously identified on the basis of ITS and cox1 haplotyping and phylogenetic analysis on samples from 2 researchers returning to Europe from CAR (4). Adult worms expelled from 1 researcher were morphologically identified as N. gorillae (3). Subsequent molecular work in CAR (12), Gabon (6), and Cameroon (13) similarly reported a zoonotic Necator sp. hookworm sharing an identical ITS haplotype (II) with those from the researchers from Europe, thus presumably representing N. gorillae. Our findings, together with those reports, indicate that N. gorillae hookworm infections could be more widespread than currently recognized in certain human communities in Central Africa. Future surveillance for hookworm infections in Central Africa should use species-specific molecular tools to differentiate between human-specific and zoonotic hookworm species.

    We do not know whether the novel Ancylostoma sp. cox1 haplotype we identified represents a zoonotic infection from NHPs or another animal, but detection of hookworm eggs in a fecal sample excludes transient passage of ingested DNA. Further investigations using longer read genotyping targets combined with morphologic analysis of harvested adult hookworms could provide more definitive speciation.

    Our findings also suggest that S. f. fuelleborni roundworm infection is common among human populations in Central Africa. However, little S. f. fuelleborni roundworm infection epidemiologic surveillance has been performed in humans in Africa since 1980, when surveys of diagnostic specimens submitted to a hospital in Lusaka, Zambia, reported a 1.0% diagnostic prevalence of S. f. fuelleborni roundworm infections over a 7-month period (14). A 2024 molecular survey conducted in Asia identified a 3.0% (4/134) infection prevalence in some Bangladesh communities (15).

    In our study, S. f. fuelleborni sequences clustered closely with isolates from Central Africa at both the cox1 and 18S rDNA HVR-IV loci, supporting the hypothesis of geographic clustering for this species (10,11,15). The S. stercoralis 18S rDNA HVR-IV haplotype we identified is consistent with previous reports of that species in humans from Africa (8,10).

    In summary, we report human infections with N. gorillae hookworms and S. f. fuelleborni roundworms in Gabon in Central Africa. Those infections occurred in a forest-edge region where localized environmental disturbance and anthropogenic activities, such as hunting and foraging in the adjacent forest, bring villagers into direct contact with NHP habitats, increasing exposure to NHP STHs (2). To determine the extent of human infections with zoonotic primate STH in areas where populations overlap and to define the clinical effects and most appropriate treatment strategies for infected persons enhanced STH surveillance is needed.

    Ms. Zhao is a PhD candidate in the School of Public Health and Tropical Medicine at James Cook University, Townsville, Queensland, Australia. Her research interests focus on the taxonomy and molecular epidemiology of Strongyloides spp. parasites at the interface of human and animal infections.


    Top

    Continue Reading

  • Scientists Turns Cockroaches into Cyborg Saviors for Disaster Rescue

    Scientists Turns Cockroaches into Cyborg Saviors for Disaster Rescue

    Singapore’s Nanyang Technological University (NTU) has just taken one of our planet’s most abhorred insects — the Madagascar hissing cockroach — and turned it into a cyborg savior.

    The breakthrough led by Professor Hirotaka Sato features the world’s first automated robotic system for assembling cyborg insects, where miniature electronic backpacks are attached to the cockroaches, turning them into biohybrid robots.

    NTU’s Cyborg Insect Factory Line

    Outfitting cockroaches with electronics for remote control isn’t new; it has been done before, but the process is excruciatingly slow; it takes an hour to assemble the electronics on an insect manually.

    NTU’s automated system, on the other hand, uses AI and computer vision to identify the best spot for placing the lightweight backpack composed of sensors, a battery, and control circuitry. In tests, the automated system completed such assemblies on four insects in under 8 minutes — 30 times faster than manual assembly!

    Aiding Time-Sensitive Operations

    More impressive was the mass-produced backpacks’ ability to stimulate the insects’ movement using 25% less voltage, thereby decreasing overstimulation and increasing energy efficiency. These factors are critical for meeting the crucial 72-hour, life-and-death window after a disaster.

    In recent tests, ten such cyborg cockroaches were sent to Myanmar as part of a humanitarian mission following a 7.7-magnitude earthquake. They proved adept at navigating rubble and tight crevices, as well as detecting human presence, something conventional robots would have failed at due to size or battery limitations.

    Reliable Cyborg Applications

    NTU has also created a swarm navigation algorithm allowing cockroaches to work in groups. These groups are led by a leader insect whose movements coordinate with the others, reminding one of robot swarms sans energy-intensive motors or high computational power.

    In real-life scenarios, this could make NTU’s cyborgs an optimal choice for inspecting critical infrastructure, military reconnaissance, and swarm-based object transport.

    Image credit: ArtMediaFactory/Shutterstock

    Find Thomasnet Suppliers and Services

    Continue Reading

  • Speech by H.E. Adylbek Kasymaliev, Chairman of the Cabinet of Ministers of the Kyrgyz Republic at the Aga Khan Award for Architecture prize-giving ceremony

    Speech by H.E. Adylbek Kasymaliev, Chairman of the Cabinet of Ministers of the Kyrgyz Republic at the Aga Khan Award for Architecture prize-giving ceremony

    His Highness Prince Rahim Aga Khan,
    Distinguished guests,
    Esteemed representatives of the global architectural community,
    Laureates of the Award,

    For the Kyrgyz Republic, hosting the Aga Khan Award for Architecture ceremony is a great honour and a profound responsibility.

    We regard the participation of more than 200 prominent architects, scholars and high-ranking guests from various countries of the world in this grand event as a sign of respect and appreciation for our nation. We are delighted to welcome you to the Ala-Too mountains, in the warm and hospitable land of Kyrgyzstan.

    Through this grand ceremony, we find ourselves at the centre of the world community’s attention. Such events are rare. Global sports Olympiads, world competitions in culture and the arts, and international exhibitions of science and technology belong to this same category of historic events. Therefore, we believe that this day will hold great significance in our history.

    Organising the World Nomad Games was already a major event that captured global attention. Today, we are witnessing the grand ceremony of a worldwide architectural competition.

    This Award, which holds special significance for the global community, has for nearly half a century been not only a recognition of outstanding architectural projects but also a symbol of humanism, cultural diversity and the pursuit of harmony between people and nature.

    Unlike many other awards, the Aga Khan Award celebrates buildings not only for their beauty or form; it also considers their impact on society, their role in preserving cultural heritage and their significance in community development. This Award clearly demonstrates that architecture is not a display of wealth, but a necessity and a responsibility to future generations.

    In a time challenged by climate change, urbanisation and social trials, it is precisely such projects that give us hope and show the way toward building a sustainable and just future.

    Kyrgyzstan has long been distinguished by its rich history, deep culture and unique architecture. The lifestyle and cultural values of our people have been reflected for centuries in architectural monuments. The ancient cities of Balasagyn and Uzgen, the historic Burana Tower, the architectural complex and mausoleums in Uzgen, and the caravanserais in Tash-Rabatall of these testify to the creativity of our ancestors and their contribution to world civilisation.

    Today, building on this heritage, we strive not only to carefully preserve it and pass it on to future generations but also to develop contemporary architecture. New constructions grounded in national characteristics and historical traditions define the identity of our country and become another remarkable symbol introducing Kyrgyzstan to the world.

    In recent years, Kyrgyzstan’s construction sector has been developing particularly dynamically. Millions of square metres of housing have been put into use, and modern schools, kindergartens, hospitals, sports complexes and cultural centres are being built.

    As of now, a new chapter in large-scale construction and architectural development is unfolding. Among these projects are:

    • The construction of Kemin-City, a new environmentally friendly city that will become a modern centre for living and business;
    • The new Jalal-Abad Airport, designed not only to enhance transit capabilities but also to incorporate energy-efficient and modern engineering solutions;
    • The Ala-Too Resort mountain-ski cluster, globally competitive yet environmentally responsible, protecting and supporting nature rather than harming it;
    • The China-Kyrgyzstan-Uzbekistan railway corridor, which will significantly strengthen the region’s transport and economic connectivity.

    These are projects that ensure not only infrastructural development but also ecological balance.

    In addition, modern schools and medical complexes being built in the regions will adhere to green standards. Furthermore, environmentally friendly technologies will be applied in the reconstruction of international highways, as well as in the construction of bridges and engineering structures, minimising their impact on the environment.

    All these initiatives not only transform the architectural appearance of our cities and villages but also create green urban environments and establish infrastructure in harmony with nature. Along with creating new jobs and strengthening social and cultural spaces, they ensure architectural development.

    Today, we stand to congratulate and honour the winners and participants of the 16th cycle of the Aga Khan Award for Architecture. It is especially symbolic that this ceremony takes place during the 25-year period of cooperation between the Kyrgyz Republic and the Aga Khan Development Network.

    The partnership between the Kyrgyz Republic and the Aga Khan Development Network over the past quarter-century has been built on trust, mutual support and creativity. Within the framework of this cooperation, joint projects in education, health care and culture have been implemented, making a significant contribution to improving the quality of life for citizens. We are ready to continue strengthening this trusted relationship and to implement new initiatives together.

    Dear laureates,

    Each of your projects inspires millions of people around the world. You have demonstrated that architecture is not merely a collection of walls and roofs, but a commitment to caring for people, protecting their dignity and safeguarding their future.

    As seen in the video above, the Khudi Bari project by Marina Tabassum Architects in Bangladesh offers a replicable solution made of bamboo and steel for communities forced to relocate due to climatic and geographical changes. The community centre in West Wusutu Village, China, was restored using brick and has become a new space for culture and dialogue, taking into account the traditions and needs of the local Hui Muslim community.

    The Revitalisation of Historic Esna project in Egypt transformed a neglected area into a thriving centre of culture and tourism, while in Iran, the Majara complex on Hormuz Island and the renovated Jahad metro station in Tehran demonstrated how traditional materials combined with innovation can breathe new life into public spaces. In Pakistan, the Vision Pakistan Center in Islamabad has become a source of education and hope for youth, and in Palestine, the Wonder Cabinet in Bethlehem united craftsmanship, innovation and culture in a unique model of connected architecture.

    Each of these projects is unique in its own way. Yet, they all share a common goal – to make architecture a tool for transformation and innovation. They serve as a factor that strengthens society and fosters unity among citizens, becoming symbols that connect generations and values. Moreover, these projects act as a bridge between traditional architecture and contemporary trends, preserving national identity while creating new spaces that meet global standards.

    On behalf of the people of Kyrgyzstan, allow me to express our deep gratitude to His Highness Prince Rahim Aga Khan. Thanks to your leadership, the Award is serving as a unique platform that brings together architects, engineers, scholars, artisans and local communities. Your contribution to the development of culture, education and architecture is invaluable.

    The Aga Khan Award for Architecture is a great initiative that reminds us that buildings are a mirror of society. The cities and structures we create today will shape the face of tomorrow. It also reflects the values we will pass on to future generations.

    Kyrgyzstan will continue to develop its construction sector, taking confident steps toward creating modern cities and villages where every individual feels part of a harmonious space, where nature and culture are preserved, and where they become the foundation of progress.

    I wholeheartedly congratulate all the winners of the 16th cycle of the Award! I express my deep gratitude to the organisers and wish you renewed inspiration, bold ideas and a firm belief that your work will make the world a better place.

    May the Aga Khan Award for Architecture continue to serve as a symbol of hope, creativity and mutual understanding for all humanity!

    Thank you for your attention.

    Continue Reading

  • Netanyahu admits Israel economically isolated, says will need to become ‘super-Sparta’

    Netanyahu admits Israel economically isolated, says will need to become ‘super-Sparta’

    Prime Minister Benjamin Netanyahu admitted on Monday that Israel is facing increasing isolation on the world stage, and will have to become a more self-reliant “super-Sparta” in the years to come.

    His comments, delivered as European countries have called for arms embargoes and sanctions against Israel during the ongoing war in Gaza, were seized on by political opponents and high-tech industry groups who blamed the premier for Israel’s troubled status on the world stage.

    “Israel is in a sort of isolation,” Netanyahu acknowledged, at a conference of the Finance Ministry’s accountant general in Jerusalem.

    “We will increasingly need to adapt to an economy with autarkic characteristics,” he continued, calling the term for economic self-sufficiency, closed off from global trade, “the word I most hate.”

    “I am a believer in the free market, but we may find ourselves in a situation where our arms industries are blocked. We will need to develop arms industries here — not only research and development, but also the ability to produce what we need,” he said.

    Faced with a scenario of “Athens and Sparta,” Israel would be “Athens and super-Sparta,” Netanyahu said. “There’s no choice; in the coming years, at least, we will have to deal with these attempts to isolate us.”

    Israel is facing two new threats since the start of the war, Netanyahu explained: demographic changes in Europe as a result of immigration from Muslim-majority countries and the influence of anti-Israel actors on digital platforms, aided by new technologies.

    The premier said these challenges had long been in the works, but came to the fore during the ongoing war sparked by the Hamas terror group’s October 7, 2023, attack in southern Israel.

    The prime minister began his speech by praising Jerusalem’s success in its military campaigns against Iran and its terror proxies throughout the region.

    According to Netanyahu, these campaigns “eliminated an existential threat that was hanging over our heads, and all of the [other] problems — economic, social, internal — would be irrelevant if we were destroyed.”

    Pedestrians walk past a mural at Palestine Square in central Tehran on July 8, 2025, as an anti-Israeli billboard is displayed on the facade of a building depicting the Prime Minister Benjamin Netanyahu with text in Persian and Hebrew reading, ‘Netanyahu lost another war; you fell victim to Bibi’s political games. Where will the next failure to stay in power occur?’ (AFP)

    He stressed, in particular, the damage done to Iran’s nuclear and ballistic missile programs, asserting that Tehran would have built a nuclear bomb or two, as well as the equivalent destructive power in ballistic missiles, within a year, had Israel not intervened.

    However, he said, Israel’s longstanding security challenges have been replaced by new diplomatic issues, which, he said, were long-maturing, but have come to the surface since the war’s start.

    PM says isolation result of EU migration, online propaganda

    Netanyahu first addressed demographic changes in Europe, where “limitless migration” has resulted in Muslims becoming a “significant minority — very vocal, very, very belligerent.” These countries’ Muslim citizens are pressuring European governments to adopt anti-Israel policies, he claimed.

    “Their focus isn’t Gaza, it’s opposing Zionism in general, and sometimes an Islamist agenda that challenges those states,” the premier added.

    “This is creating limitations, and all sorts of sanctions, on Israel — it’s happening. It’s a process that’s been at work for the last 30 years, and especially in the last decade, and that changes Israel’s international situation. Clear as day,” he said.

    The situation could bring arms embargoes and — though these are only threats for now — “the beginnings of economic sanctions,” the prime minister warned.

    Pro-Palestinian, anti-Israel protesters hold a ‘Wanted’ poster depicting Prime Minister Benjamin Netanyahu, during the 21st and last stage of the Vuelta a Espana 2025, in Madrid on September 14, 2025. (Oscar DEL POZO / AFP)

    The second challenge, according to Netanyahu, is the investment of Israel’s “rivals — both NGOs and states, like Qatar and China” — to “influence Western media with an anti-Israel agenda, using bots, artificial intelligence, and advertisements.” He cited TikTok as an immediate example.

    “This puts us in a sort of isolation,” he said, adding that Israel can fight demonization and incitement if it invests “very large sums” into efforts to counter those narratives.

    But for now, he said, Israel must quickly establish the capacity to produce everything it needs militarily without depending on foreign trade.

    Opposition fumes: PM ‘turned Israel into third-world country’

    Netanyahu’s comments drew immediate backlash from his domestic political opposition and from industry groups, as the Tel Aviv stock exchange dipped following the premier’s speech.

    Opposition Leader Yair Lapid said in a statement: “Isolation is not fate. It’s a product of a wrongheaded and failed policy by Netanyahu and his government, who have turned Israel into a third-world country, and aren’t even trying to change the situation.”

    Opposition Leader and Yesh Atid chairman MK Yair Lapid attends a Yesh Atid party conference in Tel Aviv, September 1, 2025. (Avshalom Sassoni/Flash90)

    The Democrats chair Yair Golan fumed that, “Netanyahu ‘blesses’ the citizens of Israel for the Rosh Hashanah holiday: To protect my seat, I need a forever war and isolation. And you all will sacrifice the state, the economy, and your children’s future, and their connection to the world. Our answer to this vile man: This year, we will replace you and save Israel.”

    Gadi Eisenkot, the former member of Netanyahu’s war government who recently left the National Unity party, blasted “the paralysis that has gripped Netanyahu and the ‘October 7 Cabinet’ in its management of the war in Gaza for more than a year,” adding: “If the prime minister doesn’t know how to fix the situation, then he should turn over the keys and return his mandate to the people, immediately.”

    Industry groups blast PM, as markets dip after speech

    Manufacturers’ Association of Israel President Ron Tomer said that Netanyahu “said publicly what we’ve been feeling and warning against: The Israeli brand, of creativity, demand, and success, has been seriously harmed in the world.”

    “Israeli industry will ensure that we are never lacking — not in security, not in food, and not in anything vital to the Israeli economy. That being said, an autarkic market will be a disaster for Israel’s economy and will influence every citizen’s quality of life,” he said.

    Ron Tomer, president of the Manufacturers Association of Israel attends an Economic Committee meeting at the Knesset, in Jerusalem, on January 16, 2023. (Yonatan Sindel/Flash90/File)

    The High-Tech for Israel Forum said in a statement: “Is this the prime minister’s vision — that we go back to being an orange seller?”

    And just minutes after the prime minister’s speech, leading indexes on the Tel Aviv stock exchange went down by as much as two percent, though it recovered by about half, later in the day.

    PM: China and Qatar trying to ‘besiege’ Israel

    Later on Monday, Netanyahu returned to the same themes, speaking to a delegation of 250 US state legislators at the Foreign Ministry in Jerusalem.

    “We value and cherish your support,” the premier told the delegation — the largest group of legislators from a single country ever to visit Israel — adding that “there is an effort to erode [that support].”

    “An effort to besiege — not isolate as much as besiege Israel — that is orchestrated by the same forces that supported Iran,” he continued.

    While Iran attempted “a military siege” on Israel through its network of terror proxies, and Israel was “able to break loose from that siege,” the premier said, “we will have to do several things to break loose from this siege that is organized by a few states.”

    Prime Minister Benjamin Netanyahu speaks during a ceremony at the Foreign Ministry in Jerusalem, September 15, 2025. (Olivier Fitoussi/ POOL)

    He named those states: “One is China. And the other is Qatar. They are organizing an attack on Israel… [through] the social media of the Western world and the United States. We will have to counter it, and we will counter it with our own methods,” he said.

    Later, speaking to i24 News, Netanyahu said: “Have [China and Qatar] achieved global isolation [of Israel]? No. The US is with us, as are many other countries. But we do currently have a problem centered in Western Europe, and we are working and will continue to work to remove this blockade.”

    PM dismisses ‘doom-and-gloom forecasters’

    In a second stab at damage control following the stock market dip, the prime minister said in a statement Monday evening: “To all the doom-and-gloom forecasters in economics, in the end the Israeli stock market is the strongest in the world.”

    “The shekel has strengthened, the deficit has shrunk despite the war, and foreign investment in R&D is the highest in the world after the United States. Investing in Israel is the smart thing to do,” he said.

    Netanyahu added that his government will continue to “increase investments in weapons production so as not to be dependent on weak Western European leaders who give in to the extreme Muslim minorities in their countries — and that is exactly what we are doing.”

    His office also shared a graph showing that Israel ranks second in the world in R&D investment.


    Continue Reading

  • Sri Lanka survive Hong Kong scare in Dubai

    Sri Lanka survive Hong Kong scare in Dubai

    Sri Lanka managed a four-wicket win in Dubai

    What’s the story

    Despite tumbling, Sri Lanka beat Hong Kong in Match 8 of the 2025 T20 Asia Cup at Dubai International Cricket Stadium.
    The Lankans successfully chased down what appeared to be a challenging 150, with Pathum Nissanka anchoring the chase.
    Nissanka hammered a formidable 78* after losing his opening partner, Kusal Mendis, early.
    Earlier, Anshuman Rath and Nizakat Khan played fine knocks for Hong Kong.

    Hong Kong off to fine start

    Hong Kong were off to a terrific start, with openers Zeeshan Ali and Anshuman Rath adding 41 runs.
    However, Zeeshan and Babar Hayat departed before 10 overs, leaving HK at 57/2. Dushmantha Chameera and Wanindu Hasaranga did the damage.
    However, Nizakat and Rath joined forces thereafter, taking the side past 110. The latter finally fell to Chameera, scoring 48 off 46 balls.

    Nizakat gets HK to challenging total

    While Rath departed, Nizakat remained unfazed.
    Despite seeing the departure of skipper Yasim Murtaza, he finished unbeaten on 52 off 38 balls. His knock was laced with 4 fours and 2 sixes.
    While Nizakat’s knock propelled Hong Kong to 149/4 in 20 overs, Chameera bagged figures of 4-0-29-2.
    Notably, Dasun Shanaka dismissed Murtaza in his only over.

    Special feat for Nizakat

    As per Cricbuzz, Nizakat became the second Hong Kong batter to have recorded a 50-plus score in the T20 Asia Cup.
    He joined Babar Hayat, who hammered an incredible 122 against Oman and 54 against UAE, both in 2016.
    In 118 T20Is, he raced to 2,376 runs at 22.41. His tally includes a strike rate of 121.22. This was his 12th half-century in T20Is.

    Kusal Mendis equals Kumar Sangakkara

    Kusal Mendis now has the joint-most wicket-keeping dismissals for Sri Lanka in T20Is, equaling the great Kumar Sangakkara.
    Both Mendis and Sanga now have 45 wicket-keeping dismissals across 56 innings.
    Mendis first took the catch of Zeeshan Ali in the fifth over. In the ninth over, Mendis stumped Babar Hayat to reach the landmark. Hayat came down the track against Hasaranga.

    Nissanka powers SL home

    Nissanka single-handedly powered Sri Lanka to victory in Abu Dhabi.
    He lost Kusal Mendis in the fourth over, while Kamil Mishara departed after scoring a run-a-ball 19.
    With Sri Lanka behind the required run-rate, Nissanka upped the ante and scored successive boundaries in the 13th over.
    Getting the chase under control, Nissanka was run out for a 44-ball 68 (6 fours and 2 sixes).

    SL tumble before winning

    With 32 required off 30 balls, SL were expected to win easily despite Nissanka’s runout.
    However, Murtaza dismissed Kusal Perera on the very next ball, reducing SL to 119/4.
    Charith Asalanka and Kamindu Mendis fell in the next seven balls, and suddenly, SL slumped to 127/6.
    However, Hasaranga released the pressure with a six off Murtaza. The former, along with Shanaka, sealed SL’s win.

    Continue Reading

  • Maurice Bellan Named a Finalist in the 2025 National Law Journal Awards | Newsroom

    Maurice Bellan Named a Finalist in the 2025 National Law Journal Awards | Newsroom

    Global law firm Baker McKenzie is pleased to announce that Maurice Bellan, Managing Partner of the Washington, DC, office, has been named a finalist for DC Managing Partner of the Year in the 2025 National Law Journal Awards. This recognition honors law firm leaders whose achievements and influence have made a meaningful impact on their firms, their people and clients, and society at large.

    Maurice’s selection underscores his outstanding contributions to Baker McKenzie’s DC office and the broader firm community. As a member of the Dispute Resolution Practice and a former trial attorney at the US Department of Justice, Maurice is a highly respected practitioner known for exceptional commitment to client service. As Managing Partner of the Firm’s DC office, Maurice’s impact goes beyond legal work as he actively supports junior lawyers through a strong commitment to mentorship and talent development. His dedication to mentorship was recently recognized with the Best Mentor Award in the 2024 American Lawyer Industry Awards. Maurice was also named a 2025 BTI Client Service All-Star, a select group of attorneys identified by clients for delivering truly superior client service.

    The National Law Journal Awards celebrate individuals and organizations that have made a significant impact on the legal industry and the DC area. Winners will be announced at a ceremony in November. Learn more here.

    Continue Reading