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Trump says US to hit India with 25% tariff starting August 1 – Reuters
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Formation of Lactic Acid (CH3CH(OH)COOH), a Metabolic Keystone for the Molecular Origins of Life, in Interstellar Ice Analogues
Graphical Abstract – Journal of the American Chemical Society
Lactic acid (CH3CH(OH)COOH)–a key biorelevant hydroxycarboxylic acid–is ubiquitous in living organisms and critically linked to the molecular origins of life due to its fundamental role in metabolic pathways.
With the anoxic conditions of early Earth, anaerobic metabolic pathways such as lactic acid fermentation may have served as an essential mechanism for primordial cellular metabolisms. Although lactic acid has been detected in high abundances in carbonaceous asteroid Ryugu and various meteorites like Murchison, its formation pathways under extreme conditions of the interstellar medium (low temperature, radiation) have remained elusive.
Here, we report the first bottom-up formation of racemic lactic acid via a barrierless radical–radical recombination between the hydroxycarbonyl (HOĊO) radical and the 1-hydroxyethyl (CH3ĊHOH) radical in interstellar analog ices composed of carbon dioxide (CO2) and ethanol (CH3CH2OH).
These results provide a first step toward a fundamental understanding of the abiotic formation of biorelevant hydroxycarboxylic acids via nonequilibrium reactions from ubiquitous precursor molecules in extraterrestrial environments. Utilizing isomer-selective vacuum ultraviolet photoionization reflectron time-of-flight mass spectrometry and isotopic substitution experiments, lactic acid and its isomer monoethyl carbonate (CH3CH2OCOOH) were identified in the gas phase during temperature-programmed desorption.
These findings suggest that they can likely form in interstellar ices containing carbon dioxide and ethanol in cold molecular clouds via galactic cosmic rays-mediated nonequilibrium chemistries.
Formation of Lactic Acid (CH3CH(OH)COOH), a Metabolic Keystone for the Molecular Origins of Life, in Interstellar Ice Analogues, Journal of the American Chemical Society
Astrobiology, Astrochemistry,
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You can hide an AirTag in Skechers’ new kids’ shoes
If you’re a parent with kids in school or kids who are independently exploring their neighborhood for the first time, then there’s a good chance you’ve considered stashing a tracker somewhere on their person for added peace of mind. Skechers is making that a little easier with a new line of sneakers for kids that feature a hidden compartment in the sole, which is designed to securely hold an Apple AirTag so you can track your child without worrying about the tracker itself going missing.
There are currently several different styles and color options in the company’s new Find My Skechers line, with size options ranging from toddlers to eight-year-olds. Lifting the sneaker’s insole and a fabric web liner reveals a plastic compartment recessed into the cushioned midsole that holds and protects an AirTag without inhibiting its wireless communications.
You can already find a lot of AirTag accessories that let you attach an AirTag to an active child more securely than just slipping the tracker into their pockets, where it can potentially fall out while they’re playing. Skechers’ solution goes one step further with a lid on the compartment that’s screwed into place. That should help prevent kids from tampering with it and, given the AirTag’s compact size, make it safer for toddlers still experimenting with cramming things into their mouths.
As an added safety feature, the shoes don’t feature any branding that hint at there being an AirTag inside them. They look like every other sneaker that Skechers sells, making them one of the more covert ways to keep tabs on where your kids are.
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Rise in STEC Infections Linked to Food and Overseas Travel
A sharp rise in Shiga toxin-producing Escherichia coli (STEC) infections was recorded in England in 2024, new figures from the UK Health Security Agency (UKHSA) show.
There were 2544 culture-confirmed cases, up 26% from the 2018 cases recorded in 2023. Of these, 564 were STEC serotype O157 and 1980 were non-O157 strains.
The UKHSA said the increase was largely due to non-O157 infections, including the largest outbreak linked to contaminated salad leaves. This outbreak resulted in 293 confirmed cases, 126 hospitalisations, 11 cases of haemolytic uraemic syndrome (HUS), and two deaths.
Dr Gauri Godbole, a consultant microbiologist and deputy director for gastrointestinal infections at the UKHSA, said: “While this rise is partly due to one foodborne outbreak, we have been seeing STEC cases gradually increase since 2022.”
Travel-Linked Cases Also Rising
Travel-related cases increased by 60.5%, from 114 in 2023 to 183 in 2024.
The UKHSA said this may reflect changes in international travel patterns or better collection of travel history during investigations. The exact cause remains unclear.
Long-Term Trends
Between 2015 and 2021, the number of O157 confirmed cases had been following a decreasing trend. However, case numbers had increased in recent years.
Non-O157 STEC infections have continued to rise since 2021, nearly tripling since 2019 and continuing a pre-pandemic trend.
As in 2023, the highest incidence of STEC cases in 2024 — both 0157 and non-0157 — was among children aged 1 to 4 years.
The UKHSA said this may be due to limited prior immunity, less developed hygiene practices, and a greater likelihood of parents seeking healthcare when young children were symptomatic. Contact with animals, particularly at petting farms, may also be a factor.
Causes and Outcomes
The main reservoir for STEC is cattle, although it is also carried by other ruminants such as sheep, goats, and deer. Transmission can occur through direct or indirect contact with animals or their faeces, consumption of contaminated food or water, and person-to-person spread.
In 2024, the UKHSA and partner agencies investigated five outbreaks of non-0157 STEC. Sources were identified for three: contaminated beef, fresh fruit, and salad leaves.
STEC can cause gastroenteritis, with symptoms ranging from mild to bloody diarrhoea, stomach cramps, vomiting, and dehydration. In severe cases, it can cause HUS.
According to the UKHSA, hospitalisation was reported in 27.5% of O157 and 34.3% of non-O157 cases.
HUS occurred in 2.1% of O157 and 1.7% of non-O157 cases.
There were seven deaths – two from O157 and five from non-O157.
Rob Hicks is a retired National Health Service doctor. A well-known TV and radio broadcaster, he has written several books and has regularly contributed to national newspapers, magazines, and online publications. He is based in the United Kingdom.
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Innovative technologies push pediatric MRI beyond diagnostics
From fetal stages through adolescence, the b;rain undergoes rapid, layered development—from basic motor skills to complex emotional regulation. Yet this very dynamism, coupled with children’s physical and behavioral traits, makes brain imaging extraordinarily difficult. Common conditions like autism spectrum disorder (ASD), Attention-Deficit/Hyperactivity Disorder (ADHD), and perinatal brain injury often leave subtle but critical imprints on early neural architecture. Magnetic resonance imaging (MRI) is uniquely suited to study these changes safely and in detail, but traditional approaches—designed for adult brains—struggle to keep pace with pediatric needs. Motion artifacts, small anatomy, and the sensitivity to noise or sedation present major hurdles. Due to these issues, advancing specialized pediatric MRI tools and techniques has become an urgent and transformative focus of research.
In a comprehensive review (DOI: 10.1007/s12519-025-00905-7) published May 25, 2025, in World Journal of Pediatrics, researchers led by Dan Wu from Zhejiang University outline state-of-the-art developments in pediatric brain MRI. The paper explores innovative technologies in hardware, image acquisition, processing, and analysis tailored for young brains. These efforts are revolutionizing how clinicians and scientists visualize and understand early neural development—making brain scans faster, quieter, and more precise, while addressing the unique physiological and emotional needs of children.
The review presents a sweeping look at innovations transforming pediatric MRI. Foremost are specialized radiofrequency coils—sized and shaped for infants and children—that enhance image resolution and patient comfort. Wireless coils and ergonomic incubator-compatible designs further improve flexibility and safety. To counteract the ever-present challenge of movement during scans, technologies like self-navigated imaging, external optical tracking, and real-time motion correction are dramatically reducing artifacts. Silent MRI protocols, noise-canceling hardware, and redesigned gradient coils tackle acoustic discomfort, allowing infants to sleep through procedures and reducing the need for sedation.
Speed also matters. Fast-imaging strategies such as simultaneous multi-slice scanning and compressed sensing reduce time inside the scanner without sacrificing detail. AI now plays a central role—deep learning algorithms reconstruct sharper images, correct for motion, and even perform super-resolution enhancement. Perhaps most importantly, the field is moving toward age-specific imaging atlases and contrast protocols, recognizing that a 3-month-old’s brain is fundamentally different from a toddler’s or teen’s. These tailored approaches help interpret what’s “normal” at each age and detect subtle abnormalities sooner.
Together, these technical leaps are pushing pediatric MRI beyond diagnostics—into prediction, prevention, and personalized care.
“Children are not just small adults—their brains demand entirely different imaging strategies,” says Dr. Dan Wu, the review’s corresponding author, on behalf of her team. “We’ve made significant progress toward making MRI not only faster and more accurate, but also more humane. Our innovations reduce fear and discomfort, helping us see the brain more clearly and earlier. This technology is rewriting what’s possible in developmental neuroscience.”
These breakthroughs hold far-reaching potential. By enabling clearer, faster, and gentler scans, modern pediatric MRI could become a cornerstone of routine developmental screening, especially for conditions that benefit from early intervention. Customized imaging protocols and AI-enhanced data analysis will support large-scale studies linking brain development with genetics, environment, and behavior. In the clinic, radiologists may soon be able to flag at-risk children before symptoms arise, opening doors for targeted therapy. As the technology matures, these innovations could extend globally—bringing advanced neuroimaging to underserved populations and transforming child health outcomes around the world.
Source:
Chinese Academy of Sciences
Journal reference:
Chen, R.-K., et al. (2025). Advances in magnetic resonance imaging of the developing brain and its applications in pediatrics. World Journal of Pediatrics. doi.org/10.1007/s12519-025-00905-7.
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A guide to using Edits, Meta’s CapCut rival for short-form video editing
Meta recently released a new video editing app for creators called Edits. The new app is designed to rival ByteDance’s CapCut, a popular short-form video-editing app used by many creators.
Meta first shared that it was working on Edits back in January after ByteDance-owned CapCut was removed from U.S. app stores when the TikTok ban momentarily went into effect. Although the app has since come back online and is available to download, TikTok’s future in the U.S. remains uncertain, so Meta is ready to capitalize on CapCut’s possible absence in the future with its new Edits app.
We’ve created this guide to walk you through the app and the different features it offers, and we provide an overview of how it compares to CapCut.
How to get started with the app
Image Credits:Meta Edits is available to download on both iOS and Android. Once you download the app and open it, you will be asked to log in with your Instagram account.
From there you will see five main tabs: Ideas, Inspiration, Projects, Record, and Insights. The Ideas tab offers creators a space to jot down ideas for new videos and save reels to a collection, and the Inspiration tab features a hub for discovering trending audios and other popular reels.
The Projects tab is where creators can store and revisit the videos they currently have in progress. This tab is also where creators can upload videos from their phone’s camera roll. The Record tab lets creators start filming video content right within Edits. Lastly, the Insights tab gives creators an overview of how their content is performing by surfacing metrics like views, reach, and follower counts.
Image Credits:Meta Green screen: Replace and edit the background of your videos with one tap.
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October 27-29, 2025Timeline: Precisely arrange and adjust clips.
Captions: Add automatic captions to your videos in multiple languages.
Audio library: Add music from Instagram’s library to your videos.
Cutouts: Isolate specific objects with precision tracking.
Animate: Turn static images into videos using AI.
Apply all: Apply filters, effects, transitions, and adjustments to all of your clips at once.
Timeline frame rate selector: Convert your video to the frame rate you want in order to enhance playback smoothness.
Alignment guides: Ensure viewers can see the important parts of your video when posted and accurately position text, emoji, or other elements.
Beat markers: Add auto-detected beat markers to help you align clips, text, and overlays with audio when editing.
Filters: Choose from 30 different filter options to add a unique look to your videos.
Transitions: Choose from 30 different transitions to connect different video clips in a seamless way.
Teleprompter: Follow your written script while recording.
Restyle: Use AI to change the look and style of your video with a library of presets.
Keyframes: Animate the position, rotation, and scale of clips.
Cut Silences: Automatically remove unwanted silence from reels.
Import Audio from Files: Add your own unique sounds directly into edits.
Clip Preview: Preview clips while you’re recording from the camera.
How does Edits differ from CapCut?
While both Edits and CapCut are great options for editing short-form videos, there are some differences between the two services.
CapCut offers more robust editing options, including AI features, than Edits does. Of course, this can be expected since Edits is a lot newer than CapCut. Meta will likely continue to build out Edits over the next months and years, so we can expect to see more advanced functionality in the future. It’s also worth noting that CapCut has a more extensive music library compared to Edits.
Another difference is the fact that Edits currently doesn’t have a subscription offering (for now), but CapCut does. While CapCut offers a free version, some of its advanced tools are locked behind a paid subscription. Edits is free to use, but this will likely change in the future, as Instagram head Adam Mosseri has stated that later versions of Edits may include paid features.
In addition, while CapCut is available on the web, Edits is mobile-only. However, this could change in the future.
Update: This story originally ran in May and is updated regularly with new information.
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Sensational sweeps: China in the women’s 20km race walk at the 2019 World Championships | News | Tokyo 25
As the countdown to the World Athletics Championships Tokyo 25 continues, we shine a spotlight on some of the podium sweeps that have lit up past editions of the global showpiece.
This five-part series concludes with a look back at China’s dominance in the women’s 20km race walk in Doha in 2019.
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Heading into the World Championships in 2019, heat was top of mind. While the Khalifa International Stadium in the host city of Doha in Qatar had air conditioning, the out of stadium endurance athletes faced hot and humid conditions with little relief. To alleviate the severe conditions, long distance road events began late in the evening. Just before midnight on 29 September, the women’s 20km race walk competitors took to Doha’s Corniche.
Most eyes were on two women on the starting line who were 13 years apart in age. Many knew about China’s Liu Hong, who already had a storied career. Liu had been a figure on the race walking scene since 2006, when she won the world U20 title.
In 2018 she took a year off to have a child and returned to become the first woman to ever break four hours in the 50km race walk, adding that world record to the world 20km race walk record she set in 2015. She is now a four-time world 20km race walk champion as well as a three-time Olympic medallist.
Other eyes were focused on Ecuador’s Glenda Morejon, a then 19-year-old who had posted a stellar debut at the 20km distance in La Coruña a few months prior. Outpacing China’s 2017 world champion Yang Jiayu, Liu and Qieyang Shijie in La Coruña, Morejon won in 1:25:29 – a world U20 best. But in Doha it was Liu, Qieyang and Yang Liujing who outlasted Morejon and the rest of the field to capture the first-ever women’s race walk podium sweep at the World Championships.
Yang, Qieyang and Liu worked together as a pack, but went out conservatively for the first 5km as the temperature at the start line was 32°C with 75% humidity. Liu and Qieyang gradually accelerated over the next 10km and were among those to share the lead. Liu surged with a penultimate kilometre of 4:17 and an even quicker closing kilometre of 4:09, a decisive move that would lead her to victory.
After finishing first in 1:32:53, Liu turned around to see her teammate Qieyang finish 17 seconds behind in 1:33:10 for silver, and then Yang clock 1:33:17 for bronze.
Liu Hong on her way to leading China to a sweep of the women’s 20km race walk medals in Doha (© AFP / Getty Images)
Because Chinese race walkers tend to train in high-altitude plateau camps, and the country – like Ecuador – has a tradition of success in the event, the Chinese trio frequently train together and have the opportunity to practice tactics and pacing.
Qieyang explained that teamwork was essential to the team’s overall success.
“The weather conditions were really a big challenge for us,” she noted. “Thanks to our teamwork, we had a better strategy, and we just battled as a team.”
The podium sweep carried extra significance as it happened just before the National Day of the People’s Republic of China, a holiday that celebrates the establishment of the proclamation of the People’s Republic of China, initially celebrated on 1 October 1949.
Liu saw the sweep as a present to the nation. “The three medals, this achievement is a good gift that we give to our motherland,” she said.
In addition to the gift to China, Liu was able to bring her medal as a gift to her child, symbolically paving the way for the new generation.
Hannah Borenstein for World Athletics
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Gautam Gambhir vs The Oval curator: Ex-BCCI umpire Couto recalls Gambhir’s previous ‘fight’ in domestic match – ‘He was very aggressive with curators’ | Cricket News
MUMBAI: Reports of India head coach Gautam Gambhir’s public spat with The Oval’s curator Lee Fortis during the Indian team’s practice session at the venue on Tuesday, ahead of the fifth Test invoked a feeling of ‘deja-vu’ in former BCCI & Mumbai umpire Marcus Couto.Go Beyond The Boundary with our YouTube channel. SUBSCRIBE NOW!More than 11 years back, on March 1, 2014 to be precise, Couto witnessed a similarly fiery verbal fight between Gambhir, then the Delhi captain (he was dropped from the Indian team at that time and bidding to make a comeback) and the pitch curator at the Feroz Shah Kotla Stadium in Delhi, before a Vijay Hazare Trophy (for one-dayers) about the wicket for the match.
Tension had been brewing between Gambhir and Kotla curator Venkat Sundaram that season, with Gambhir clearly unhappy about the pitch preparation at Kotla and preferring to play Delhi’s matches at the Roshanara Club instead. Sundaram had even accused Gambhir of abusing him during the Ranji Trophy, something which the feisty left-hander vehemently denied.“It was a Vijay Hazare Trophy match between Delhi and Punjab, in Delhi. It was my farewell game as a BCCI umpire, before we were recalled years later after the retirement age. We, the match officials, had gone to the Kotla for a pre-match meeting with the captains, Gambhir (Delhi) and Harbhajan Singh (Punjab), and then suddenly we saw Gambhir and the Delhi curator (not Sundaram) involved in a heated argument, following which Gambhir literally chased him out of the ground! Gambhir just wasn’t happy with the pitch that the curator had prepared. To tell you the truth, the pitch was very bad, as the ball barely rose above ankle height in the match. Later, that maali (groundsman) told me that Gambhir was very aggressive with the curators,” recalled Couto while talking to TOI on Wednesday. “I was reminded of that incident when I saw reports of Gambhir involved in a similar spat with The Oval curator yesterday,” he added.
Interestingly, while Couto was umpiring in his final BCCI match, it was a List A debut for the other on-field umpire, Jiwanjot Singh. For the record, Punjab bowled out Delhi for 228 and won that match by four wickets, with star bat Yuvraj Singh scoring an unbeaten 95-ball 96.This isn’t the first time that a visiting team captain or coach has clashed with a curator before an international game. A similar clash, about the curator instructing the opposition players to not come too near the match pitch had occurred between Sri lankan captain Kumar Sangakkara and the then Wankhede curator, former India opener Sudhir Naik just before the historic 2011 World Cup final between India and Sri Lanka at the Wankhede Stadium in Mumbai. Years later, Naik recalled that tiff with the Lankan skipper while talking to this correspondent, “Will you tell Sachin (Tendulkar) to not come near the pitch?’ Sangakkara told me. ‘Don’t worry. Sachin will never come so near the pitch on match-eve,’ I replied.”
Oval Pitch curator was ‘problematic’ for the
Indian women’s team tooMeanwhile, India’s batting coach Sitanshu Kotak wasn’t off the mark when he said that “everyone knows that The Oval curator isn’t the easiest man around.” It seems that Lee Fortis wasn’t very popular with the Indian women’s team which toured England and played a T20I match at The Oval on July 4.“Like in the case of the Indian men’s team, he was very rude to the Indian women’s team. He didn’t let the team practice peacefully on both the practice day and match day. It was difficult to conduct our bowling and fielding sessions with him around. Ultimately, the matter had to be escalated to the concerned authorities,” a source in the Indian women’s team told TOI.
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Zed code editor hears your prayers, rolls out AI-free mode • The Register
Zed, a fast new Rust-based text editor aimed at programmers, now lets you totally disable LLM bot integration. We’re sure some users will rejoice – but how many?
“You Can Now Disable All AI Features in Zed,” the developers announced late kast week, and by the time you read this, it should be available in the latest build of the editor. At the time of writing, it’s in Preview build 0.197.
It’s an interesting move, given that the Zed Industries homepage puts AI integration front and center. Even so, Zed users have been calling for this for about a year, citing issues such as corporate rules forbidding use of public LLM tools, so they can’t risk installing it.
We wrote about Zed a year ago when the first Linux version appeared. Text editors are old news, but Zed has a few interesting characteristics. It’s written in Rust, so it’s a compiled native app on the two OSes it supports so far. It’s smaller, although not by much – the approximately 100 MB Linux Flatpak brings in about a gigabyte of dependencies. And it’s fast, which is one reason generative AI skeptics like it. Internally, it’s built around conflict-free replicated data types, which means collaborative online editing without being built around any particular cloud provider. (This also means a built-in chat tool, which seems a bit like overkill to us, but what do we know?)
Notably, several members of the team previously developed the Atom editor, the app that brought Electron apps to the world – those built in JavaScript and bundled with a very cut-down instance of Chromium. Electron apps are everywhere now. They deliver the “write once, run anywhere” promise Java made 30 years ago, but with a high price. Rather than Java’s system-wide JVM, every Electron app must embed its own copy of the huge runtime.
We do mean huge. For instance, Balena Etcher, one of the easiest FOSS tools for writing disk images onto USB keys, is an Electron app, meaning that there are versions for Windows, Linux, and macOS, and they’re functionally identical. But the compressed downloads are in the region of 150-200 MB. By comparison, the Rufus tool for Windows is about 2 MB (1 percent the size), and the cross-platform USBImager is under 200 kB (which is about a tenth of Rufus).
For the vendor, Electron means building and offering separate downloads for each OS. For the user, it means there’s no way to update them all at once.
GitHub owner Microsoft killed Atom three years ago in favor of its own Electron-based editor VS Code. Zed was announced the next day.
Native app, smaller, faster, built-in collaboration – all good things. That it’s from the people who created Atom is a fun footnote. Still, it did strike us that it’s a sign of the times when “now available without AI” takes a year to develop and is seen as a significant advance.
The Register frequently reports on problems under the tag of AI-pocalypse, and recently covered a study that found developers were 20 percent slower using GenAI assistants, although they thought they were that much faster. Executives are losing faith, too.
Last month, the excellent Pivot to AI reported that GenAI is similar to gambling addiction – the same sort of behavioral patterns that lead gamblers to just one more bet, the big one that will pay off all their debts and make them rich. Instead, LLM-addicted vibe coders fervently believe that “just one more prompt” will give them the killer app that will make them rich. It’s like digital cocaine. As Natalie Ponte put it on LinkedIn, to understand the hype, try replacing the abbreviation “AI” with the word “cocaine.” For example:
There’s some reason to think that the hype bubble around GenAI may soon deflate. There are reports that the AI bubble is now bigger than the dotcom one, a quarter of a century ago. Maybe a bot-free Zed will remain useful once all those cheap subsidized LLMs in the cloud go away. ®
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Swimmer Kate Douglass on playing the long game for LA 2028, her friendship with Paralympian Ali Truwit and more
Kate Douglass: “I’m enjoying my life outside of swimming”
Even as she’s aimed to strike a balance in her life overall, Douglass qualified for the 2025 World Aquatics Championships in Singapore across three individual events: The 100m breaststroke, 200m breaststroke, and 50m butterfly.
On Tuesday (29 July), she earned silver in the 100m breaststroke for Team USA, behind Germany’s surprise winner in Alana Elendt, and will race the remainder of her events in the coming days. It’s a barometer test on the world’s biggest stage, yes, but one that Douglass is seeing with that aforementioned long-game approach in mind.
“This year and next year are kind of about just chilling a little bit,” she said. “Trying not to train too hard, but doing enough to where I can show up to these meets and be confident and swim fast.
She continued: “I’m enjoying my life outside of swimming, I think, for the year, year and a half, [which] is really important to be able to get me to be really good in 2028.”
Is LA 2028 potentially the end of the lane for the 23-year-old New York native?
“That’s probably where I will end my swimming career,” she said before pausing and laughing. “Who the hell knows! But yeah, that’s kind of in the distant future.”
It’s not a future she isn’t thinking about, however. The four-year plan has worked out well so far, starting with the sun, the beach and an adult beverage in her hand on vacation after Paris. Since then, she’s settled into a consistent pace in Charlottesville, Virginia, where she had competed for the University of Virginia, exploring its surprisingly robust cafe culture in search of her favourite combination: An excellent cappuccino and warm pan au chocolat.
“I’ve been trying out a lot of great coffee shops and bakeries in Charlottesville,” she said, smiling. “I think that’s my favourite thing, especially when I’m travelling. … It’s definitely [become] an important part of my morning routine.”
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