Blog

  • Flares On TRAPPIST-1 Reveal The Spectrum Of Magnetic Features On Its Surface

    Flares On TRAPPIST-1 Reveal The Spectrum Of Magnetic Features On Its Surface

    Stellar flares observed in JWST/NIRISS time-series spectroscopy of TRAPPIST-1. Each column shows one flare event during transits of the TRAPPIST-1c or TRAPPIST-1f planets. Tow row: Light curves with the total flux (integrated over the full spectral range and normalized to the mean out-of-transit flux). Colored points indicate pre-flare (green), flare (orange), maximum flare light (red), and post-flare (blue) phases. Green and blue dashed lines mark the average pre- and post-flare flux levels. Middle row: Light curves of the normalized Hα flux. Bottom row: Time-resolved spectrograms (wavelength vs. time) normalized to the pre-flare spectrum. The shaded blue region shows the drop in flux caused by the planetary transit. For comparison, the time axis in all panels are aligned such that t = 0 corresponds to the beginning of the maximum flare light phase. In all four events, the total flux in the post-flare phase is systematically elevated relative to the pre-flare level. — astro-ph.EP

    TRAPPIST-1 is an M8 dwarf hosting seven known exoplanets and is currently one of the most frequently observed targets of the James Webb Space Telescope (JWST).

    However, it is notoriously active, and its surface is believed to be covered by magnetic features that contaminate the planetary transmission spectra. The radiative spectra of these magnetic features are needed to clean transmission spectra, but they currently remain unknown.

    Here, we develop a new approach for measuring these spectra using time-resolved JWST/NIRISS observations. We detect a persistent post-flare enhancement in the spectral flux of TRAPPIST-1.

    Our analysis rules out lingering flare decay as the cause of the flux enhancement and, thus, points to structural changes on the stellar surface induced by flares. We suggest that the flaring event triggers the disappearance of (part of) a dark magnetic feature, producing a net brightening.

    This suggestion is motivated by solar data: flare-induced disappearance of magnetic features on the solar surface has been directly detected in high spatial resolution images, and our analysis shows that this process produces changes in solar brightness very similar to those we observe on TRAPPIST-1.

    The proposed explanation for the flux enhancement enables, to our knowledge, the first measurement of the spectrum of a magnetic feature on an M8 dwarf. Our analysis indicates that the disappearing magnetic feature is cooler than the TRAPPIST-1 photosphere, but by at most a few hundred kelvins.

    Valeriy Vasilyev, Nadiia Kostogryz, Alexander I. Shapiro, Astrid M. Veronig, Benjamin V. Rackham, Christoph Schirninger, Julien de Wit, Ward Howard, Jeff Valenti, Adina D. Feinstein, Olivia Lim, Sara Seager, Laurent Gizon, Sami K. Solanki

    Comments: accepted for publication in The Astrophysical Journal Letters
    Subjects: Earth and Planetary Astrophysics (astro-ph.EP); Solar and Stellar Astrophysics (astro-ph.SR)
    Cite as: arXiv:2508.04793 [astro-ph.EP] (or arXiv:2508.04793v1 [astro-ph.EP] for this version)
    https://doi.org/10.48550/arXiv.2508.04793
    Focus to learn more
    Submission history
    From: Valeriy Vasilyev
    [v1] Wed, 6 Aug 2025 18:09:01 UTC (4,502 KB)
    https://arxiv.org/abs/2508.04793
    Astrobiology, Space Weather,

    Continue Reading

  • Pakistan Open to US Mediation on Kashmir Dispute Ahead of Army Chief Asim Munir’s Visit – Firstpost

    Pakistan Open to US Mediation on Kashmir Dispute Ahead of Army Chief Asim Munir’s Visit – Firstpost

    Pakistan welcomes US or any country’s mediation to resolve the Kashmir dispute, ahead of Army chief Asim Munir’s US visit. India rejects third-party involvement, citing the Simla Agreement.

    read more

    Pakistan on Friday expressed openness to mediation from the United States or any other country to help resolve the Kashmir dispute.

    Foreign Office spokesperson Shafqat Ali Khan, speaking at his weekly press briefing, said Pakistan would welcome assistance “from any country which can help stabilise the situation and move towards resolution” of the issue.

    The statement came ahead of Pakistan Army chief Asim Munir’s reported visit to the US this week, his second in two months following recent military skirmishes with India. The trip comes at a time when India–US ties are strained over trade tariffs.

    STORY CONTINUES BELOW THIS AD

    ”About the US’ interest in settlement of the Kashmir issue, we welcome help not only from the US but any country which can help stabilise the situation and move towards resolution of the Kashmir dispute, which is at the heart of issues of peace and security in South Asia. We will welcome that,” he said.

    India maintains that it does not want any third-party involvement in its discussions with Pakistan. The Simla Agreement signed between the two countries in 1972 rejects any third-party mediation on the Kashmir issue.

    To a question about any contact between Pakistan and India to resolve issues after their four-day conflict in May, Khan said there was no such contact but added that “we welcome the US’ interest to work with the two sides for the resolution of this issue”.

    “Our overall diplomatic position is well known. We want to take the route of diplomacy, but it is the Indian side which has to make up its mind. And so far, there are no contacts between our two sides, except for the routine diplomatic contact,” he said.

    India has made it clear that it will only have a dialogue with Pakistan on the return of Pakistan-occupied Kashmir and the issue of terrorism.

    Talking about the terrorism in Khyber-Pakhtunkhwa and Balochistan, he said Pakistan highlighted the issue of terrorism emanating from Afghanistan on several occasions.

    He also rejected speculation about any secret agreement with the US to extract minerals. ”There is no question of any secret agreements or Pakistan compromising on its national interest. At the same time, there is a mechanism through which we invite Foreign Investment,” he said.

    STORY CONTINUES BELOW THIS AD

    He also rejected as “baseless” the allegations of the involvement of Pakistani nationals in the Ukraine conflict and said Islamabad has not been formally approached by the Ukrainian authorities on the issue.

    With inputs from agencies

    Continue Reading

  • Nephrogenic Diabetes Insipidus: Three Decades of Clinical Reality

    Nephrogenic Diabetes Insipidus: Three Decades of Clinical Reality


    Continue Reading

  • Intranasal Insulin Shows Promising Brain Uptake Patterns in Alzheimer Disease

    Intranasal Insulin Shows Promising Brain Uptake Patterns in Alzheimer Disease

    Intranasal insulin can safely and effectively reach key memory regions of the brain in older adults and could aid new treatments for Alzheimer disease (AD), according to a new brain imaging study from Wake Forest University School of Medicine. The study authors, who published their findings in Alzheimer’s & Dementia: Translational Research & Clinical Interventions, noted that the results also demonstrated that, when delivered through a simple nasal spray, individuals with early cognitive decline absorb the insulin differently than others.1,2

    Image credit: Atlas | stock.adobe.com

    “One of the biggest challenges in developing treatments for brain diseases is getting agents into the brain,” Suzanne Craft, PhD, professor of gerontology and geriatric medicine at Wake Forest University School of Medicine and director of the Wake Forest Alzheimer Disease Research Center, said in a news release. ”This study shows we can validate intranasal delivery systems effectively, an essential step before launching therapeutic trials.”2

    AD & Insulin

    Individuals with AD have a buildup of proteins in the form of amyloid plaques and neurofibrillary tangles in the brain that cause brain cells to die and the brain to shrink over time. According to Mayo Clinic, around 6.9 million individuals 65 years and older live with AD.3

    Despite its prevalence, effective treatments for AD and mild cognitive impairment are lacking. While antiamyloid antibodies offer potential benefits, they do not address causes like insulin dysregulation or impaired neuroplasticity. Metabolic and vascular disorders raise AD risk by disrupting insulin regulation, leading to inflammation, blood vessel issues, and reduced brain plasticity, suggesting that treatments for these conditions could be repurposed to help treat AD.1,2

    Previous animal and human studies have found that intranasal insulin reaches the brain without affecting blood sugar and has shown promise in improving cognition and brain activity and reducing AD pathology.1,2

    “There’s an urgent need to identify effective and feasible ways to prevent and treat [AD],” said Craft in the news release. “These findings show that we can now validate whether treatments are actually reaching their intended brain targets, which is critical information for designing successful trials.”2

    Intranasal insulin for AD

    To further assess how intranasal insulin reaches the brain, researchers conducted a first-in-human positron emission tomography study, including 16 older adults with an average age of 72. Seven of the individuals were cognitively normal, and 9 had mild cognitive impairment. Using a new radiotracer, [68Ga]Ga-NOTA-insulin, and a 6-spray delivery system, individuals underwent brain and whole-body imaging, reporting that the spray was easy to use.1,2

    The results demonstrated a high insulin uptake in key memory regions, such as the hippocampus and temporal lobe. Additionally, cognitively normal individuals had higher and more sustained insulin absorption than those with mild cognitive impairment. In women, insulin uptakes were associated with better cardiovascular health, while a marker of brain amyloid levels was linked with reduced brain absorption.1,2

    “The results of the study represent a significant step forward in medicine, as they validate that our nasal delivery system was effective in delivering intranasal insulin safely and effectively to specific regions of the brain,” Reenal Gandhi, director of business development for Aptar Pharma, said in the news release. “As scientific understanding and development advance, we see continued opportunities for intranasal delivery to improve how therapeutics are delivered to the central nervous system.”2

    The study authors noted that the treatment was well tolerated, with only 2 individuals reporting mild headaches that were short-lived.1,2

    “While there’s still a lot to learn, these findings show that we now have the tools to validate intranasal drug delivery to the brain,” Craft concluded in the news release. “This is promising news for developing more effective and accessible treatments for AD.”2

    REFERENCES
    1. Sai K. Erichsen J. Gollapelli K. et al. First-in-human positron emission tomography study of intranasal insulin in aging and MCI. Alzheimer’s & Dementia: Translational Research & Clinical Interventions. Volume 11 (2025) doi.org/10.1002/trc2.70123
    2. New study validates insulin nasal spray to deliver Alzheimer’s drug directly to the brain. EurekAlert! News release. July 23, 2025. Accessed August 8, 2025. https://www.eurekalert.org/news-releases/1092108
    3. Alzheimer’s Disease. Mayo Clinic. News release. November 8, 2024. Accessed August 5, 2025. https://www.mayoclinic.org/diseases-conditions/alzheimers-disease/symptoms-causes/syc-20350447

    Continue Reading

  • A decade later, Windows is still bringing Control Panel features to the Settings app

    A decade later, Windows is still bringing Control Panel features to the Settings app

    Microsoft has tried to dumb down its Control Panel with a simple UI over the years, rather than a list of options, but there’s still a number of settings that don’t exist in the new PC Settings app. “Why do I have to go the PC settings to forget a network and Control panel to change IP settings? Can’t this all be done from a single place?” It’s a fair criticism, and one that Microsoft should look to address with Windows 10.

    Continue Reading

  • Validation of TESS Planet Candidates with Multi-Color Transit Photometry and TRICERATOPS+

    Validation of TESS Planet Candidates with Multi-Color Transit Photometry and TRICERATOPS+

    Ground-based light curves from LCOGT, KeplerCam, and MUSCAT2. The colored data points correspond to the binned data at 5 minute cadence. The solid black line is the median model from the posterior distribution. The solid blue curve is the median TESS light curve projected into the corresponding band. — astro-ph.EP

    We present an upgraded version of TRICERATOPS, a software package designed to calculate false positive probabilities for planet candidates identified by the Transiting Exoplanet Survey Satellite (TESS).

    This enhanced framework now incorporates ground-based light curves in separate bandpasses, which are routinely obtained as part of the candidate vetting process. We apply this upgraded framework to explore the planetary nature of 14 TESS planet candidates, combining primarily J band light curves acquired with the 200-inch Hale Telescope at Palomar Observatory with complementary archival observations from the Las Cumbres Observatory Global Telescope (LCOGT), the Fred Lawrence Whipple Observatory (FLWO), and the Teide Observatory, along with existing TESS data and contrast curves from high-resolution imaging.

    As a result of this analysis we statistically validate (False Positive Probability < 1.5% and Nearby False Positive Probability < 0.1%) six new planets in five systems: TOI-1346 b, TOI-1346 c, TOI-2719 b, TOI-4155 b, TOI-6000 b, and TOI-6324 b. For these systems, we provide updated estimates of their stellar and planetary properties derived from the TESS and ground-based observations. These new systems contain planets with radii between 0.9-6 Re and orbital periods between 0.3-5.5 days.

    Finally, we use our upgraded version of TRICERATOPS to quantify the relative importance of multi-wavelength transit photometry and high-resolution imaging for exoplanet candidate validation, and discuss which kinds of candidates typically benefit the most from ground-based multi-color transit observations.

    Jonathan Gomez Barrientos, Michael Greklek-McKeon, Heather A. Knutson, Steven Giacalone, W. Garrett Levine, Morgan Saidel, Shreyas Vissapragada, David R. Ciardi, Karen A. Collins, David W. Latham, Cristilyn N. Watkins, Polina A. Budnikova, Dmitry V. Cheryasov, Akihiko Fukui, Allyson Bieryla, Avi Shporer, Benjamin M. Tofflemire, Catherine A. Clark, Chris Stockdale, Colin Littlefield, Emily Gilbert, Enric Palle, Eric Girardin, Felipe Murgas, Galen J. Bergsten, Hugh P. Osborn, Ian J. M. Crossfield, Jerome de Leon, Jesus Higuera, Keisuke Isogai, Mark E. Everett, Michael B. Lund, Norio Narita, Richard P. Schwarz, Roberto Zambelli, Steve B. Howell

    Comments: 26 pages, 7 Figures, accepted for publication in AJ
    Subjects: Earth and Planetary Astrophysics (astro-ph.EP)
    Cite as: arXiv:2508.02782 [astro-ph.EP] (or arXiv:2508.02782v1 [astro-ph.EP] for this version)
    https://doi.org/10.48550/arXiv.2508.02782
    Focus to learn more
    Submission history
    From: Jonathan Gomez Barrientos
    [v1] Mon, 4 Aug 2025 18:00:03 UTC (3,592 KB)
    https://arxiv.org/abs/2508.02782
    Astrobiology,

    Continue Reading

  • The Possibility Of A Giant Impact On Venus

    The Possibility Of A Giant Impact On Venus

    Snapshots of a cross-sectional slice of a head-on collision between a non-rotating Venus and a 0.1 M⊕ impactor at 10 km s−1 . shown at multiple time steps. Initial energy deposition at the impact site generates pressure waves that converge at the antipode, causing significant heating and deformation. The outcome of this collisions is a merger. — astro-ph.EP

    Giant impacts were common in the early evolution of the Solar System, and it is possible that Venus also experienced an impact. A giant impact on Venus could have affected its rotation rate and possibly its thermal evolution.

    In this work, we explore a range of possible impacts using smoothed particle hydrodynamics (SPH). We consider the final major collision, assuming that differentiation already occurred and that Venus consists of an iron core (30% of Venus’ mass) and a forsterite mantle (70% of Venus’ mass). We use differentiated impactors with masses ranging from 0.01 to 0.1 Earth masses, impact velocities between 10 and 15 km/s, various impact geometries (head-on and oblique), different primordial thermal profiles, and a range of pre-impact rotation rates of Venus.

    We analyse the post-impact rotation periods and debris disc masses to identify scenarios that can reproduce Venus’ present-day characteristics. Our findings show that a wide range of impact scenarios are consistent with Venus’ current rotation. These include head-on collisions on a non-rotating Venus and oblique, hit-and-run impacts by Mars-sized bodies on a rotating Venus.

    Importantly, collisions that match Venus’ present-day rotation rate typically produce minimal debris discs residing within Venus’ synchronous orbit. This suggests that the material would likely reaccrete onto the planet, preventing the formation of long-lasting satellites – consistent with Venus’ lack of a moon.

    We conclude that a giant impact can be consistent with both Venus’ unusual rotation and lack of a moon, potentially setting the stage for its subsequent thermal evolution.

    Mirco Bussmann, Christian Reinhardt, Cedric Gillmann, Thomas Meier, Joachim Stadel, Paul Tackley, Ravit Helled

    Comments: Accepted for publication in A&A, 12 pages, 9 figures
    Subjects: Earth and Planetary Astrophysics (astro-ph.EP)
    Cite as: arXiv:2508.03239 [astro-ph.EP] (or arXiv:2508.03239v1 [astro-ph.EP] for this version)
    https://doi.org/10.48550/arXiv.2508.03239
    Focus to learn more
    Submission history
    From: Mirco Bussmann
    [v1] Tue, 5 Aug 2025 09:12:48 UTC (5,186 KB)
    https://arxiv.org/abs/2508.03239
    Astrobiology,

    Continue Reading

  • 'We Have Lost Our Way'; Bee Venom for Breast Cancer; Gene Test to Cut Side Effects – MedPage Today

    1. ‘We Have Lost Our Way’; Bee Venom for Breast Cancer; Gene Test to Cut Side Effects  MedPage Today
    2. Bee Venom Could Help Treat a Type Of Cancer  Newsweek
    3. Bee venom quickly targets and kills aggressive breast cancer cells  The Brighter Side of News
    4. “Important Progress” Made in Studying Bee Venom To Cure This Type of Cancer  Green Matters

    Continue Reading

  • Scientists discover an organism that defies the definition of life

    Scientists discover an organism that defies the definition of life

    A tidy textbook definition of life has never existed, yet most biology lessons still lean on the idea that living things must grow, make energy, and reproduce on their own.

    That simple checklist leaves viruses outside the club, since their genetic shells activate only inside another organism and go dormant again when drifting alone.


    Ryo Harada of Dalhousie University and colleagues discovered a creature that forces us to redraw those lines on the fly.

    Their oddball microbe, provisionally named Sukunaarchaeum mirabile, was hiding in DNA scraped from a single plankton species off the Japanese coast.

    Sukunaarchaeum virus line blurs

    Biologists once leaned on André Lwoff’s dictum that “an organism is constituted of cells.” That rule pushed viruses into a separate realm of particles.

    That neat boundary already looked wobbly when giant viruses surfaced in the early 2000s, flaunting genomes larger than some bacteria.

    Sukunaarchaeum muddies the waters further. It is undeniably cellular, yet its playbook borrows many viral tricks. It retains the genes for building its own ribosomes and messenger RNA – parts no virus carries – but appears to outsource nearly every other task to a host cell.

    A record-breaking small genome

    The new organism’s entire genome fits into 238,000 base pairs – roughly the length of a medium-sized magazine article.

    For comparison, the minimalist archaeon Nanoarchaeum equitans holds the previous cellular record at about 490,000 base pairs, already microscopic by prokaryotic standards.

    Viruses can be both larger and smaller, yet they never lug around the full toolkit for protein synthesis. That is why Harada’s team calls Sukunaarchaeum “a cellular entity retaining only its replicative core.”

    A virus-like microbe emerges

    “Its genome is profoundly stripped-down, lacking virtually all recognizable metabolic pathways, and primarily encoding the machinery for its replicative core: DNA replication, transcription, and translation,” wrote Harada and co-authors in their report.

    The code resembles a viral instruction manual more than a self-sufficient microbe.

    Yet the creature sits within Archaea, one of the three great domains of life – not among viruses. Phylogenetic trees place it on a deep branch so distant from known groups that the authors propose creating a new phylum.

    Sukunaarchaeum and borrowed genes

    The team stumbled on the microbe while sequencing DNA from the dinoflagellate Citharistes regius. Nested in that plankton’s genetic debris was a tight loop of foreign DNA that refused to match any catalogued species.

    Marine symbiosis can be intimate: some plankton rely on bacterial partners for vitamins, while others house entire algal cells that photosynthesize for them.

    Sukunaarchaeum appears to take this intimacy to the extreme, shaving off every gene it can afford to lose and leaning on its host for nearly everything else a cell needs to stay alive.

    Redrawing the tree of life

    Because its ribosomal genes remain intact, the organism qualifies as cellular under the classic molecular litmus test.

    Yet its pared-down metabolism likely prevents it from harvesting nutrients, producing ATP, or fixing carbon without help – behaviors normally reserved for viral passengers.

    Phylogenetic analyses place Sukunaarchaeum as a deeply branching lineage within the tree of Archaea, representing a novel major branch distinct from established phyla. Environmental sequence data indicate that sequences closely related to Sukunaarchaeum form a diverse and previously overlooked clade in microbial surveys. Credit: JSPS
    Phylogenetic analyses place Sukunaarchaeum as a deeply branching lineage within the tree of Archaea, representing a novel major branch distinct from established phyla. Environmental sequence data indicate that sequences closely related to Sukunaarchaeum form a diverse and previously overlooked clade in microbial surveys. Click image to enlarge. Credit: JSPS

    Scientists debate whether life is a binary label or a spectrum; Sukunaarchaeum pushes the spectrum view to the forefront.

    The find suggests that many other stealth lineages may be hiding in environmental sequencing data, dismissed as contaminants or viral oddities.

    Defining the meaning of “alive”

    Words such as “alive” steer funding, public health policy, and even planetary protection rules for space probes.

    If more organisms like Sukunaarchaeum exist, biosecurity protocols that screen only for free-living microbes could miss entire classes of symbiotic parasites.

    The discovery also sharpens a practical question: What genetic load is the bare minimum for a cell to function? Synthetic biology groups pursuing engineered minimal cells may mine this archaeon’s blueprint for clues.

    “The discovery of Sukunaarchaeum pushes the conventional boundaries of cellular life and highlights the vast unexplored biological novelty within microbial interactions,” wrote the researchers.

    Harada’s team suspects that extreme genome pruning evolved because the host environment guaranteed nutrients, letting redundant pathways decay. 

    Paleobiologists see a glimpse of early evolution, when ancient cells likely shared genes and resources more freely than today.

    If so, today’s viruses and streamlined symbionts may echo an ancient lifestyle rather than representing biological outliers.

    Sukunaarchaeum may not be alone

    Scientists plan to investigate whether similar organisms exist in other marine ecosystems or symbiotic relationships.

    These searches may involve reanalyzing existing metagenomic databases that could contain overlooked sequences resembling Sukunaarchaeum.

    Another goal is to identify the specific host that enables Sukunaarchaeum to survive.

    Without knowing its exact partner, researchers can’t fully explain how the symbiosis functions or what evolutionary pressures shaped such an extreme dependency.

    The study is published in bioRxiv.

    —–

    Like what you read? Subscribe to our newsletter for engaging articles, exclusive content, and the latest updates. 

    Check us out on EarthSnap, a free app brought to you by Eric Ralls and Earth.com.

    —–

    Continue Reading

  • Waterslide cracks open on world’s largest cruise ship, injuring one passenger

    Waterslide cracks open on world’s largest cruise ship, injuring one passenger

    An acrylic waterslide on Royal Caribbean’s Icon of the Seas broke open on Thursday, injuring one passenger and leaving a sizable hole in the bottom of the tubular slide.

    “Our team provided medical care to an adult guest when acrylic glass broke off a water slide as the guest passed through the slide,” a Royal Caribbean Group spokesperson said in a statement.

    “The guest is being treated for his injuries. The water slide is closed for the remainder of the sailing pending an investigation.” The guest is in stable condition.

    Video captured by bystanders after the slide cracked open shows water pouring out of a hole in a section of the colorful slide that passes over the deck.

    According to Royal Caribbean’s website, Icon of the Seas has six waterslides in a waterpark called Category 6, which it says is the “largest waterpark at sea.” The park is located on decks 16 and 17 of the behemoth ship, which is currently the world’s largest cruise ship in operation.

    Icon of the Seas embarked on its maiden voyage in January 2024. The ship can carry nearly 10,000 people at full capacity.


    Continue Reading