BMC Medicine is calling for submissions to our new Collection on weight loss interventions and their health impacts, emphasizing a variety of strategies, including dietary changes, physical activity, pharmacological treatments, and surgical options. We encourage submissions that explore the long-term effects of these interventions, adherence challenges, and strategies to address health inequities. The goal is to advance understanding and improve outcomes in weight management and overall health.
Weight loss interventions encompass a wide range of strategies aimed at reducing body weight and improving health outcomes. These interventions can include dietary changes, increased physical activity, pharmacological treatments, and surgical options such as bariatric surgery. As the global prevalence of obesity and related comorbidities continues to rise, understanding the efficacy and mechanisms of various weight loss interventions becomes increasingly crucial for public health. This Collection seeks to explore the diverse methodologies and outcomes associated with weight loss interventions, offering insights into their impacts on both individual and population health.
In addition to physical outcomes, psychological and behavioral aspects—including mental health, eating disorder pathology, and patient motivation—play an important role in treatment outcomes, adherence, and health-related quality of life. Addressing these dimensions is critical for the long-term success and personalization of weight loss interventions.
The significance of this research is underscored by the growing body of evidence linking obesity to numerous chronic health conditions, including diabetes, cardiovascular diseases, and certain types of cancer. Advances in pharmacological treatments, such as SGLT2 inhibitors and GLP-1 agonists, have emerged as promising options for weight management, demonstrating not only weight loss but also improved metabolic health. There are, however, challenges and limitations related to drug availability, healthcare delivery, and long-term treatment adherence with rapid weight gain when stopping treatment. Additionally, integrating behavioral strategies with nutritional and physical activity interventions has shown potential in enhancing adherence and long-term success. By further investigating these modalities, we can develop comprehensive approaches that address the multifactorial nature of obesity.
Continued research in this domain may yield innovative strategies that harness technology, such as mobile health applications and telehealth, to support weight loss interventions. As we deepen our understanding of the genetic, environmental, and behavioral factors influencing obesity, personalized interventions tailored to individual needs could emerge. This progress may lead to improved health outcomes, reduced health inequities, and ultimately a shift in the paradigm of obesity treatment and prevention.
We are looking for original manuscripts on topics including, but not limited to:
- Clinical trials investigating interventions for weight loss, including combination approaches, to promote health
- Real-world data on long-term effects and challenges of weight loss interventions
- Factors affecting long-term adherence to weight-loss or weight maintenance interventions
- Aspects related to mental health, psychological factors, socio-economic constrains and motivation in relation to outcome of weight-loss interventions
- Challenges and inequities in access to weight loss interventions
- Impact of policy and factors promoting an obesogenic environment on treatment of obesity and management of associated health issues
All manuscripts submitted to this journal, including those submitted to collections and special issues, are assessed in line with our editorial policies and the journal’s peer review process. Reviewers and editors are required to declare competing interests and can be excluded from the peer review process if a competing interest exists.
This Collection supports and amplifies research related to SDG 3: Good Health and Well-being
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