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  • Apple iPhone 17 Air To Feature A19 Pro Chipset With Fewer GPU Cores For Slimmer Design, Claims Tipster

    Apple iPhone 17 Air To Feature A19 Pro Chipset With Fewer GPU Cores For Slimmer Design, Claims Tipster

    Fixed Focus Digital’s track record includes accurate leaks such as revealing the “iPhone 16e” name for Apple’s upcoming iPhone SE successor, reported Macrumors.

    Apple is likely to launch the iPhone 17 series on Sep. 9. On July 13, Bloomberg’s Mark Gurman suggested that Apple’s keynote event would occur during the week beginning Monday, Sep. 8. While Monday is possible, Gurman believes Tuesday, Sep. 9, or Wednesday, Sep. 10, are more probable dates for the launch.

    This predicted launch date has been confirmed by a leak from German tech site iPhone-ticker.de. Citing information from German mobile carriers, the publication reports that all four iPhone 17 models — iPhone 17, iPhone 17 Air, iPhone 17 Pro and iPhone 17 Pro Max — will be launched on Sep. 9. The handsets are then expected to ship the following week, with deliveries beginning on Friday, Sep. 19.

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  • Scientists unearth 'cute' but fearsome ancient whale – France 24

    1. Scientists unearth ‘cute’ but fearsome ancient whale  France 24
    2. ‘Deceptively cute’ ancient whale with razor-sharp teeth and eyes the size of tennis balls discovered in Australia  The Guardian
    3. A cornucopia of tiny, bizarre whales used to live in Australian waters – here’s one of them  The Conversation
    4. Fossil reveals species of ancient whale previously ‘unknown to science’  Australian Broadcasting Corporation
    5. Beach walker stumbles upon new Australian ocean predator with ‘extremely sharp’ teeth  Yahoo News Australia

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  • Indian PM Modi likely to meet Trump in US next month, newspaper reports – World

    Indian PM Modi likely to meet Trump in US next month, newspaper reports – World

    Indian Prime Minister Narendra Modi is likely to meet President Donald Trump during a visit to the United States next month to attend the UN General Assembly meeting, the Indian Express newspaper reported on Wednesday, citing sources.

    India’s foreign ministry did not immediately respond to a request for comment. An Indian official familiar with the matter said a decision has not yet been taken, and that countries usually reserve slots for the General Debate at the assembly, which is why India’s “head of government” features in a provisional list of speakers on September 26.

    “The list will go through revisions,” the official said, adding that it had not yet been decided if Modi would be going to the assembly. The General Assembly kicks off on September 9, but the debate, the annual meeting of heads of state and government, will be held from September 23-29.

    Although the reason for the potential visit will be to attend the UN meeting in New York, a key objective will be to hold talks with Trump and iron out trade and tariff issues that have led to some souring of ties between the two countries, the newspaper reported.

    News of a possible Modi trip to the US comes days after Trump announced an additional 25 per cent tariff on Indian goods to penalise New Delhi for continuing to buy Russian oil.

    The penalty took the total levy on Indian goods exported to the US to 50pc, among the highest levied on any US trading partner.

    Trade talks between New Delhi and Washington collapsed after five rounds of negotiations over disagreement on opening India’s vast farm and dairy sectors and stopping Russian oil purchases.

    On Tuesday, US Treasury Secretary Scott Bessent said several large trade agreements were still waiting to be completed, including with Switzerland and India, but New Delhi had been “a bit recalcitrant” in talks with Washington.

    Bessent told Fox Business Network’s Kudlow he hoped the Trump administration could wrap up its trade negotiations by the end of October.
    “That’s aspirational, but I think we are in a good position,” he said, adding, “I think we can be, we will have agreed on substantial terms with all the substantial countries.”

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  • Blender Animation of Industrial Scene with Moving Trains

    Blender Animation of Industrial Scene with Moving Trains

    Check out this satisfying animation with packed railways, created by 3D Artist Marcel Deneuve using Blender, with compositing completed in After Effects. The detailed setup is not only visually engaging but also highlights the technical challenge of managing the fluid train movement in such a packed railway. 

    Marcel Deneuve showcased more Blender setups with complex technical structures, such as this space scene:

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  • Description of patients presenting with mental illness in emergency medical services: a retrospective observational study | Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

    Description of patients presenting with mental illness in emergency medical services: a retrospective observational study | Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

    The main findings of this study show that intoxication and suicide threats/attempts are the most common symptoms of patients in the EMS with mental illness. Moreover, one-fifth of those assessed by EMS clinicians were hospitalised. Overall, this seems to be a difficult patient group to triage under the current triage system since four out of ten patients were not assigned a triage colour.

    Previous research conducted in Asia [16] and Scotland [15] has shown that patients who are intoxicated with alcohol and/or drugs are common in the EMS. This was likewise evident in the present study. Holzer and Minder [24] gathered data over ten years, looking at patients who had intoxication as the primary reason for assessment in the EMS, and they found an increase over time by approximately 5% per year. In the present study, patients who were intoxicated stood for the highest number of hospitalisations, although the number is low in relation to the summation of patients assessed due to intoxication. Smith-Bernardin, Kennel and Yeh [25] conducted a study on patients who were intoxicated by alcohol and examined whether the emergency department is the right referral for these patients. They found the sobering centre as a safe alternative to the patients being referred to emergency departments. In Sweden though, sobering centres exist in only six regions but is something being discussed at the government level due to the increasing number of intoxications [26]. In an interview study, patients who use the EMS when intoxicated expressed guilt over using ambulance resources but at the same time, most patients reported an unwillingness to change their alcohol misuse and depend on external support, leading to the continued frequent use of the EMS service [16]. These contradictions of feeling guilty but not accepting care could be explained by the shame and feeling of being judged for alcohol misuse that patients express [27]. One might assume that the suffering these patients experience is due to this conflict of interest. The question remains, however, whether the emergency department is the right level of care for these patients, as being transported to and being in, the emergency department could cause additional stress for the patient. On the other hand, you could assume that it at the same time brings relief as the patients get access to care quickly, which could increase the patient’s sense of safety.

    Another finding that stood out in the present study was suicide threats/attempts, with suicide threats being the most common initial assessment by dispatchers. Worldwide, more than 720,000 people die every year from suicide, and for every suicide, there are many previous threats and attempts [28]. In Sweden, 1617 people were either confirmed to have committed suicide (82%) or suspected of doing so (18%) in 2023 [29]. It is therefore unsurprising that EMS clinicians meet these patients often, something supported by previous research [30, 31]. In many cases, the suicide threats/attempts are in combination with intoxication in intentional ways to try to commit suicide [30, 31]. However, in the present study, not one patient got suicide as an ICD 10 code assigned after EMS assessment, although we can conclude that these patients got “F99 Mental Disorder” as the diagnosis code, as the number is consistent with the number of patients assessed initially due to suicide threat/attempt. These patients did not tend to be admitted to the hospital, based on the findings that none of the patients got suicide ideation or suicide attempt as an ICD 10 code when admitted, which is concerning since, as stated earlier, for every suicide, there are several threats and attempts [28]. Research [32] has also shown that the feeling of hopelessness may be a contributing factor to repeated suicide attempts, which can be interpreted as a desire to be seen and get help, rather than a desire to die. One might assume the suffering these patients experience when calling for help and not receiving care. Patients who called for the EMS while being in a suicidal process describe in an interview study the suffering they are in, in such a vulnerable place, feeling suicidal, and at the same time they struggle with the stigma and fear of being judged [33]. Drawing the conclusion they were coded with “F99 Mental Disorder” and were referred to the emergency department but then not admitted makes you wonder where these patients should receive care, for their suicidal ideation, that is sustainable in the long run, to avoid trips to the emergency departments.

    In line with this, neither intoxication nor suicide threats/attempts seems to be sufficient to allow admission to the hospital, where the present study shows that only one-fifth of the patients referred to the emergency department were admitted to the hospital. However, it is important to clarify that in the present study, we do not know if the patients wanted to be hospitalised. For example, patients who were in a suicidal process described that the most important thing for them was to be seen, heard, and acknowledged as human beings in their suffering and receive validation of their feelings [33]. It still raises the question of whether the emergency department was the right place for referral or where these patients should be referred to have their care needs met. In the present study, approximately 30% of the patients got either Red or Orange as a triage colour, indicating the need for acute care. The other patients got a lower triage colour, indicating there was no need for acute care. Previous research shows that many patients with mental health problems have sought care in primary care but did not receive help for their illness, leading the patients to call for an ambulance [13, 14]. Patients with mental illness describe how important it is to be acknowledged as a person and receive care for their mental illness. When being dismissed, this could increase the suffering [18]. One might assume the helplessness and suffering these patients feel, not receiving the care they need or being admitted anywhere [hospital, primary care]. However, in the present study, the EMS clinicians only referred the patients to primary care in 3% of the cases as most patients were transported to the emergency department. This could be because of a lack of competence and confidence in the EMS clinicians when assessing patients with mental health problems [10, 11], leading the EMS clinicians to play it safe and take the patient to the emergency room for instant care, instead of referring to primary care [34]. It could also be due to the lack of decision support and guidelines regarding where to refer the patient, leaving it up to the EMS clinician to go with their gut feeling and intuition [11]. These factors in combination could be the cause of why patients are referred to the emergency department when there is not always a need for acute care [35]. Another suggestion for why EMS clinicians refer patients to the emergency department when acute care is not always needed is the desire to help these patients as EMS clinicians witness their difficulty with mental health problems and receiving help from primary care and therefore drive the patient to the emergency department in the hope of helping them get the ball rolling [11]. On the other hand, another reason why patients are not referred to the emergency department, as outlined in the previous study, could be because of the difficulty in triaging patients with mental health problems as the current triage system WEST [21] is mainly focused on physical health problems, not mental health problems. The fact that there are no indications for the different triage colours within mental health problems; rather, it states that there are no individual warning signs for mental illness and that the EMS clinicians need to make their own assessment based on the clinical assessment, with special consideration for suicidal thoughts, psychotic symptoms, and aggressivity. This could be why 40% of the patients in the previous study were missing a triage colour or, referred to the emergency department, and then were not admitted; in other words, there is a lack of decision support and guidelines making it hard to assess the patient’s to the right level of care.

    Patients with mental illness are already struggling with stigmatisation in society and describe how they felt ashamed when calling for an ambulance due to mental health problems as they were afraid of not being taken seriously [27]. At the same time, the present study, strengthened by several other studies [13, 14, 17, 35] suggests that the EMS and emergency department are not the right place for these patients. The question remaining is how these patients should receive care and where the EMS clinicians should refer them to alleviate their suffering. This needs to be addressed in future research.

    Method discussion

    When extracting the data from EMS records, one inclusion criterion was that the patients had to be over 13 years old. This age was determined by the fact that, in Sweden, health services consider patients at the age of 13 to be cognitively developed enough to start taking responsibility for care contacts; thus parents have limited access to their medical records. We believe this cognitive development also reflects on their actions and feelings when it comes to mental illness, making over 13 years an age at which we could identify as many patients as possible in as wide an age range as possible.

    During the manual review, 389 patients were excluded for not having mental health problems as the primary focus. These patients were included in the original dataset because they met the inclusion criteria. However, upon manual review, it was found that a patient could have, for example, called an ambulance for a fracture and had a mental illness in their medical history. However, as mental illness had nothing to do with the assessment, they were excluded.

    Strengths and limitations

    The main strength of this study was a large database of 1300 patients assessed specifically for mental illness. It provides a diversity to the data which increases generalisability and reliability. However, a limitation was that mental illness can disguise itself as physical illness. This means there may be an underreporting in the actual statistics of those assessed by the EMS for mental illness, as data were retrieved from specific variables that were directly related to mental illness.

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  • Bullish announces pricing of upsized initial public offering

    Bullish announces pricing of upsized initial public offering

    Not investment advice. Digital assets and related products are high risk. Consult your professional advisor and trade responsibly. Services are available to eligible customers in select locations. Visit legal for more important information and risk warnings.




    Copyright © 2025 Bullish Global. All rights reserved.

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  • Japan’s Nikkei tops 43,000 for first time ever, extends rally to sixth session By Reuters – Investing.com

    1. Japan’s Nikkei tops 43,000 for first time ever, extends rally to sixth session By Reuters  Investing.com
    2. Japanese Shares Retreat on Profit Taking  TradingView
    3. Nikkei 225 and S&P/ASX200 surge to fresh record highs  FXStreet
    4. Amid heightened expectations of a rate cut, the level reached the 43,000 yen range.  富途牛牛
    5. Japan stocks higher at close of trade; Nikkei 225 up 1.48%  Investing.com

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  • New approach enables accessible, rapid and qualitative characterization of graphene materials

    New approach enables accessible, rapid and qualitative characterization of graphene materials

    Researchers at King’s College London have developed a new approach to characterize graphene-based materials (GBMs), including graphene oxide and graphene, based on surface interactions with a series of probe molecules.

    The team at King’s College London designed the new ‘interactional fingerprinting’ method that creates a unique identity of individual samples. By mimicking humans’ sense of taste and smell, the method can create a qualitative snapshot of the material without relying on inaccessible gold-standard measurement machinery manned by teams of specialists. It is said to be more simple and low-cost to perform. 

     

    By promising this faster and cheaper way to perform quality control on graphene materials, the scientists hope to remove barriers to exploiting them, unleashing advances in sustainable electronics, cleaner battery technology and more.

    The new work uses a first-of-its-kind molecular probing device to characterize GO in a fraction of the time and cost.

    Principal author, Dr. Andrew Surman, Senior Lecturer in Chemistry at King’s College London, explains: “Graphene Oxide is really promising. But if we’re to make good progress, we need to confirm that a new batch is like the last one. If your supply is unreliable – and behaves differently every time – how do you go about designing better products? Commercial services to test a new batch are expensive and can take weeks. That’s not often feasible.

    “Our approach should allow researchers and materials producers to perform a test in a couple of hours, using cheap tools they likely already have access to, to quickly quality control their samples where they work. By helping teams troubleshoot variation in their supply it helps ensure what they are working with is up to scratch, freeing them up for the important business of innovation in next-generation technology.”

    Their method mixes small samples of GO dispersed in water with a series of molecular probes that fluoresce until they interact with the material’s surface.

    Because these molecules have been tuned to be sensitive to desirable qualities in the material, such as oxygen level and graphene flake size, the pattern of fluorescence changes across the material can be mapped by mathematical methods to provide an ‘interactional fingerprint’. This characterizing snapshot can then be used to distinguish different kinds of GO, such as those that may be low in oxygen content.

    As the device is material agnostic, the authors hope that their probe methodology can be applied to other advanced materials like borophene to facilitate transition out of the lab and into the market.

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  • Researchers find CFI deficiency alarmingly high in old order Amish

    Researchers find CFI deficiency alarmingly high in old order Amish

    Researchers from the Children’s Hospital of Philadelphia (CHOP) and the Clinic for Special Children found that complement factor I (CFI) deficiency, an ultra-rare genetic disorder that can cause debilitating neuroinflammation, is more than 4500 times more likely to be found in individuals of Old Order Amish ancestry than in the rest of the global population.

    These findings could help clinicians better recognize the disease and develop a standard of care, particularly for Amish patients affected by this disease. The findings were published by the Journal of Allergy and Clinical Immunology.

    CFI deficiency is a genetic disorder that affects the immune system, often resulting in a high likelihood of recurrent bacterial infections, and in some cases, vascular and neuroinflammatory symptoms requiring hospitalization and acute management. In addition to genetic factors, ethnic background or epigenetic influences like lifestyle, environmental exposures, and diet can influence the trajectory of the disease, which is estimated worldwide to affect fewer than one in a million births but as high as 1 in 730 members of the Old Order Amish community.

    The Clinic for Special Children, which provides clinical care to children and adults with complex medical disorders and has a specific focus on the treatment and research of disorders affecting the Old Order Amish and Mennonite communities, was alerted to an Old Order Amish patient at CHOP presenting with acute neuroinflammatory symptoms of unknown cause.

    Rapid exome sequencing identified a variant of unknown significance in the gene CFI, which was found to be the underlying cause of her disease and directed her targeted management and recovery. This case motivated researchers to determine if other members of the Old Order Amish community also harbored this genetic finding, as they share a common genetic heritage, agrarian lifestyle, and environmental exposures. Further investigation found it was quite common and contributed to the disease in multiple Amish individuals.

    The first patient presented with headache, decreased consciousness, and weakness on one side of her body, which an MRI confirmed was due to brain inflammation. She was transferred to CHOP due to the severity of her condition and ultimately needed neurosurgical intervention.”


    Vincent J. Carson, MD, Study Co-Senior Author and Pediatric Neurologist, Clinic for Special Children

    He added, “Rapid exome sequencing, which can provide genetic diagnoses in a matter of days, was done at CHOP and confirmed the diagnosis of CFI deficiency. As a result, she was treated with a specific monoclonal antibody that blocks the complement cascade, called Eculizumab. This resulted in the resolution of the brain inflammation, leading to a full recovery.”

    The Clinic for Special Children knew that patients with Old Order Amish ancestry carried the CFI gene, but did not yet know that a particular variant caused disease. This led to a collaboration between the Clinic for Special Children and CHOP to learn more about the incidence of brain inflammation in CFI deficiency.

    “What started as a case report turned into a population study,” said co-senior study author Neil D. Romberg, MD, an attending physician with the Division of Allergy and Immunology at CHOP. “There is a striking level of enrichment of this genetic variant in the Amish community, and now that our understanding of this disease in this population has been expanded, we can offer personalized treatment plans for these patients to help them recover and get back to a normal life within their community.”

    “There are about 430 genetic disorders that we treat and counting, and since hundreds of thousands of Amish and Mennonites living in this country can trace their ancestry back to about 80 Amish founders and 240 Mennonite effective founders, we know that certain disorders are much more prevalent while others that are more common in the general population rarely affect this community,” said Laura Poskitt, DO, medical director of the Clinic for Special Children. “With the consent of our patient communities, we’ve been able to maintain a database that helps us learn more about genetic variants that may be more common in these patients in particular.”

    When focusing on 11 Amish patients who had this variant, five of the patients had presented with critical neuroinflammatory diagnoses. Those patients recovered with the aid of high dose steroids, and one patient had a clinical response to eculizumab, a monoclonal antibody used to treat several diseases linked to the immune system.

    “We have heard from patients treated for this disease that they’ve been able to recover and get back to being active members of their community, so we want to make sure we can properly identify any potentially affected patient and provide them with effective options for managing this disorder,” said first study author Whitney Reid, MD, an attending physician in the Division of Allergy and Immunology at CHOP. “In speaking with this community, they are asking good questions and want to be involved in ways that can not only help affected Amish but anyone who is impacted by this disease.”

    “Getting to the root cause of the disease is a game changer,” Carson said. “All patients with inflammation of the brain or spinal cord who have Amish heritage should be tested for CFI deficiency. Knowing this allows us to use targeted treatments, such as eculizumab, and change the course of the disease.”

    Source:

    Children’s Hospital of Philadelphia

    Journal reference:

    Reid, W., et al. (2025). Complement factor I deficiency–associated neuroinflammatory disease among Old Order Amish. Journal of Allergy and Clinical Immunology. doi.org/10.1016/j.jaci.2025.06.021 

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  • Hunza Shisper Glacier Flood Cuts Off Karakoram Highway, Isolates Communities in Gilgit-Baltistan – Pashto News and Current Affairs Channel

    Hunza Shisper Glacier Flood Cuts Off Karakoram Highway, Isolates Communities in Gilgit-Baltistan – Pashto News and Current Affairs Channel

    HUNZA – Massive flooding caused by water discharge and soil erosion from the Hunza Shisper Glacier has brought devastation to Gilgit-Baltistan. The disaster has cut off the Karakoram Highway (KKH) and left several communities completely isolated.

    Local officials said the flooding has entirely blocked the key KKH route, disrupting Pakistan–China trade and halting all local transport. An alternative link road has been arranged for small vehicles, but heavy traffic is stuck for now.

    In Hassanabad, the glacier’s outflow submerged residential houses. Authorities had evacuated these homes earlier, preventing casualties. A hotel was damaged, while hundreds of trees were swept away. Farmland in Hunza and Shigar has been destroyed, leaving farmers with heavy losses.

    Government spokesperson Faizullah Faraq confirmed that the floodwaters have reached Shigar in Baltistan. He said standing crops, fertile fields, and water channels have been damaged. “Gilgit-Baltistan is facing its worst flood disaster,” he stated. He also revealed that more than 50 labourers narrowly escaped the fast-rising water.

    The Hunza Shisper Glacier flooding has caused severe damage to infrastructure. Electricity poles and fibre optic lines have been destroyed, cutting communication in affected areas. Large boulders and frequent landslides continue to fall along the Silk Road, creating serious risks for rescue teams.

    The KKH at Hunza remains blocked, leaving passengers stranded for days. Authorities have promised to start rehabilitation work on the road soon.

    The Gilgit-Baltistan government has instructed the Hunza administration to speed up relief operations. Volunteers trying to repair water channels in dangerous conditions escaped without injury. However, residents still face shortages of essential supplies as access to the area is extremely limited.

    Officials warn that with the glacier discharge still continuing, the risk of further flooding from the Hunza Shisper Glacier remains dangerously high.

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