- Israeli strikes kill 12 in Lebanon, including 5 Hezbollah fighters, source says Reuters
- Thousands in northern Gaza flee after forced evacuation threat by Israel Al Jazeera
- At least 12 killed in Israeli attack on Lebanon refugee camp Dawn
- Katz says strikes in Lebanon are ‘clear message’ to both Hezbollah and Beirut The Times of Israel
- 6 injured as Israeli jets stage airstrikes in Lebanon’s Baalbek despite ceasefire Anadolu Ajansı
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Israeli strikes kill 12 in Lebanon, including 5 Hezbollah fighters, source says – Reuters
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Martin Scorsese, Ron Howard Nominated for First Emmys for Acting
Martin Scorsese and Ron Howard received their first ever acting Emmy nominations on Tuesday for their appearances in Apple TV+’s The Studio.
The two were nominated in the best guest actor in a comedy series category alongside The Studio costars Dave Franco Bryan Cranston and Anthony Mackie, as well as The Bear‘s Jon Bernthal.
The Studio was also nominated in the best comedy series category, and received acting nominations for Seth Rogen, Ike Barinholtz, Kathryn Hahn and Catherine O’Hara.
The series stars Rogen (who also co-created it) as Matt Remick, a movie executive who is elevated to president of the fictional Continental Studios and quickly realizes he might be in over his head.
O’Hara, Hahn, Barinholtz and Chase Sui Wonders also star in The Studio. Cranston has a key recurring role, and the show has a long list of cameos so far, among them Scorsese, Olivia Wilde, Zac Efron, Howard, Ice Cube, Charlize Theron and Nick Stoller.
Rogen and Goldberg co-created the series with Peter Huyck, Alex Gregory and Frida Perez. They executive produce with James Weaver of Point Grey, Alex McAtee and Josh Fagen.
See the full list of nominations here.
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World’s oldest marathon runner dies in a hit-and-run at 114
Fauja Singh, a torchbearer at the 2012 London Olympics and the world’s oldest marathon runner, died Monday in a hit-and-run, according to police in the northwestern Indian state of Punjab. He was 114.
Born in India in 1911, Singh lived much of his life in London. On Oct. 13, 2011, in Toronto, he set a flurry of world age-group records at a meet established especially for him, the Ontario Masters Assn. Fauja Singh Invitational.
Singh, nicknamed the “Turbaned Tornado,” ran the 100 meters in 23.14, 200 meters in 52.23, 400 meters in 2:13.48, 800 meters in 5:32.18, 1500 meters in 11:27.81, one mile in 11:53.45, 3000 meters in 24:52.47 and 5000 meters in 49:57.39. He was 100 years old.
“He rested between the events by sitting down and having a few sips of tea,” Ontario Masters official Doug Smith told the New York Times in 2017. “He was actually running — both feet off the ground.
“It was the most astonishing achievement.”
Singh became the first centenarian to finish a marathon three days later, completing the Toronto Waterfront Marathon in 8 hours, 11 minutes and 6 seconds. He didn’t begin the race until 14 minutes after the starting gun because of the congestion of runners, so his official time was 8:25:17.
Guinness World Records wouldn’t recognize the feat because Singh didn’t have a birth certificate. India didn’t keep official birth records when he was born in 1911. The birth date on his passport was April 1, 1911.
A Punjabi Sikh, Singh moved to London in 1992 to live with an adult son after his wife, Gian Kaur, a son and a daughter died. He took up running two years later to alleviate his grief after the death of his fifth son, Kuldip.
“The villagers would tell one of his sons to take him to the UK because he would keep visiting the cremation ground and sit there for hours,” his biographer, Khushwant Singh, told NDTV.
Running soon became his passion. Easily identified by his long white beard and orange Sikh turban, Singh was honored with a letter from Queen Elizabeth II of England when he turned 100 and was the subject of a biography launched in the House of Lords.
In all, Singh completed nine marathons and ran his last competitive race in February 2013 when he was 101, finishing a 10K run in Hong Kong in 1 hour 32 minutes and 28 seconds.
Singh returned to India during the pandemic and was hit by a car Monday while on his daily walk in his home village of Beas Pind. He died in a hospital, his former coach Harmander Singh told the New York Times.
“We would always tell him that someone his age running in India would always run the risk of being hit given how reckless the driving here is,” Khushwant Singh said. “This is what ultimately happened, unfortunately,”
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Renault Group announces the appointment of Duncan Minto as Interim Chief Executive Officer
Boulogne-Billancourt, July 15, 2025 – The Board of Directors of Renault Group has decided to appoint, as of July 15, 2025, Duncan Minto as Chief Executive Officer of Renault S.A., for an interim period until the appointment of the new Chief Executive Officer.
Currently CFO of Renault Group, Duncan Minto will ensure the day-to-day management of the company alongside Jean-Dominique Senard, who will hold the position of Chairman of Renault s.a.s., the operating company of the Group, during this period.Since 1997 in the Group, Duncan has a solid experience in finance and a deep understanding of the issues at stake.
The selection process for the new Chief Executive Officer of Renault S.A. is already well underway, overseen by the Governance and Remuneration Committee of the Board of Directors.
Renault Group will publish its half-year results on July 31.
Born in 1975, Duncan Minto graduated from the University of St Andrews in Scotland. Duncan Minto joined Renault Group in the UK in 1997. In 2001, he joined the Group’s Finance Department in France, where he was in charge of investor relations. He was then appointed Finance Director of Renault-Nissan Portugal in 2006, before becoming Managing Director of Renault Ireland in 2012, then CFO of the Group’s Asia-Pacific region in 2013. In 2017, Duncan Minto was promoted to VP Finance, Group Control Analysis. He was then appointed CFO of Dacia in 2022, before becoming CFO of the Alpine brand in 2023. On March 1, 2025, he was appointed Chief Finance Officer of Renault Group and became a member of the Leadership Team.
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Battles on both ends of the standings in the spotlight in Ljubljana
The Netherlands are also fielding a very young team in the VNL 2025 and find themselves fighting against relegation after the first two weeks. Filling the big shoes of Nimir Abdel-Aziz at opposite, Michiel Ahyi has been performing well for the Dutch, having tallied 124 points so far. Outside hitter Tom Koops, who leads the VNL in passes (81) and ranks sixth in digs (59) and middle blocker Luuc van Der Ent, who’s sixth in blocks (18), have also been delivering solid performances.
“The two-week break before the third week was good for us,” setter Wessel Keemink explained. “Our first week was decent, but on the second, not much worked for us. We’ve got to practice hard, build some confidence, and I hope we get into these matches with more confidence. We need to play as a team and hopefully get the results that we need.”
Sitting at the bottom of the VNL standings, Serbia desperately need to score points this week to avoid relegation. One of the veterans in the team, opposite Drazen Luburić is their leading scorer, with 102 points. Middle blocker Aleksandar Nedeljković has scored 22 blocking points and ranks fourth in the VNL in the category. Fighting to stay in the VNL, head coach Gheorghe Crețu is set to bring setter Nikola Jovović and outside hitter Pavle Perić to the court this week.
“Our team struggled in the past two weeks, but there’s always light at the end of the tunnel,” Jovović remarked. “I hope that Pavle and I can help the team get some wins. We lost some tough matches at the end of sets, and our situation is now very serious, so we need to manage to be better in the last four matches. All four opponents here will be very strong, but we’ll give our best and try something new to get the results.”
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High-Resolution DNA Methylation Profiling in Single Cells
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Complete the form below to unlock access to ALL audio articles.Scientists at the Van Andel Institute have introduced a new method for analyzing DNA methylation in individual cells. The technique, called scDEEP-mC, enables high-resolution mapping of methylation patterns across the genome, enhancing the ability to detect subtle and cell-specific epigenetic features.
DNA methylation is a chemical modification that helps regulate gene expression and cell identity without altering the DNA sequence itself. It plays a critical role in development, cell differentiation and genomic stability. Aberrant methylation patterns have been linked to a range of diseases, including cancer.
Until now, techniques for assessing methylation in single cells have lacked the resolution and efficiency required for broad application. scDEEP-mC addresses these limitations by generating comprehensive methylation maps of of DNA methylation that allow researchers to identify distinct cell types and trace developmental changes at the individual cell level. The method also allows for comparisons between newly replicated and older cells, which could provide insights into aging and disease progression.
Detailed epigenetic profiles in individual cells
The study, published in Nature Communications, describes how scDEEP-mC supports several advanced analyses in single cells. These include the estimating of cellular age using epigenetic clocks, analysis of hemimethylation and creation of whole-chromosome X-inactivation epigenetic profiles.
The improved resolution allows researchers to study methylation dynamics during DNA replication, a process that was previously difficult to observe at the single-cell level.
“scDEEP-mC allows us to see DNA methylation at varying stages of DNA replication in individual cells — something that has not been possible until now,” said Nathan Spix, Ph.D., co-first author of the study and a postdoctoral fellow. “For example, scDEEP-mC can help us pinpoint early DNA methylation changes in single cells that go on to become cancerous. If we know what goes wrong in the early stages of this process, we can use that information to develop new ways to detect and treat disease.”
Previous single-cell methylation methods relied on pooled data from multiple cells, which obscured cell-specific differences. Such averaging techniques limited the ability to identify rare cell types or detect nuanced epigenetic variations. In contrast, scDEEP-mC generates detailed individual cell profiles, revealing differences that would otherwise remain hidden.
The method’s efficiency and depth of coverage position it as a valuable tool for studying complex tissues, where understanding individual cell behavior is essential for unraveling disease mechanisms.
Reference: Spix NJ, Habib WA, Zhang Z, et al. High-coverage allele-resolved single-cell DNA methylation profiling reveals cell lineage, X-inactivation state, and replication dynamics. Nat Commun. 2025;16(1):6273. doi: 10.1038/s41467-025-61589-1
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President Zardari, PM Shehbaz reiterate commitment to work together for country – Pakistan
President Asif Ali Zardari and Prime Minister Shehbaz Sharif on Tuesday reiterated their commitment to working together with each other for the country’s sake.
A statement issued by the Presidency said the two held a meeting today at the President House.
“The meeting involved discussions on the country’s political, economic, and security situation. The state of law and order in the country and measures against terrorism were also discussed.
“The prime minister briefed the president on the government’s measures to improve the economy. Both leaders reiterated their commitment to work together for the country’s stability, development, and prosperity,” the statement said.
The meeting was also attended by Defence Minister Khawaja Muhammad Asif, Planning Minister Ahsan Iqbal, Law Minister Azam Nazeer Tarar, Interior Minister Mohsin Naqvi and PM’s Adviser on Political and Public Affairs Rana Sanaullah.
The meeting comes in the wake of growing speculation about the upcoming 27th constitutional amendment and it being claimed that President Zardari may soon step down, potentially paving the way for the army chief to assume the country’s presidency.
The reports on social media claim that work is underway to replace the current parliamentary system with a presidential form of government. Some reports also claim that President Zardari has set one condition for his exit — a key role for his son Bilawal Bhutto-Zardari in the new dispensation.
Naqvi said earlier this month that there were no plans to remove President Zardari and dismissed the reports about any such move.
He had to dismiss the reports again last week, claiming that the country was shifting to a presidential system and that Field Marshal Asim Munir would replace Zardari as head of state.
“We are fully aware of who is behind the malicious campaign targeting President Asif Ali Zardari, Prime Minister Shehbaz Sharif and the chief of army staff (COAS). I have categorically stated that there has been no discussion — nor does any such idea exist — about the president being asked to resign or the COAS aspiring to assume the presidency,” Naqvi had posted on X.
He said the president enjoyed a strong and respectful relationship with the leadership of the armed forces. “I know who is spreading these falsehoods, why they are doing so, and who stands to benefit from this propaganda.”
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Tim Davie insists he is still right person to lead BBC after series of scandals | Tim Davie
Tim Davie has insisted he is still the right person to lead the BBC, after a succession of controversies that have led the culture secretary to accuse him of overseeing a “series of catastrophic failures”.
Davie has been under the most intense pressure of his five-year tenure as director general after incidents including the livestreaming of Bob Vylan’s performance at the Glastonbury festival, as well as the broadcast of a Gaza documentary that breached the corporation’s editorial guidelines.
This week, the BBC also admitted opportunities were missed to deal with the behaviour of Gregg Wallace, after an independent report substantiated 45 allegations made against the former MasterChef presenter, including claims of inappropriate sexual language and one incident of unwelcome physical contact.
It has led to criticism from the culture secretary, Lisa Nandy, who suggested the corporation was suffering from a failure in leadership.
However, Davie insisted there had been consequences for staff responsible for the Glastonbury broadcast and a Gaza documentary that failed to disclose that its child narrator was the son of a Hamas official.
Speaking at the launch of the BBC’s annual report, Davie said he had already taken action to improve the culture at the BBC after previous high-profile scandals such as the departure of the disgraced presenter Huw Edwards – including the dismissal of staff.
In a defence of his performance, Davie said the controversy around Gaza: How to Survive a Warzone had been the most challenging he had dealt with during his tenure. However, he said he was the right person to lead the BBC as it faced an onslaught of competition from streamers and a continued decline in the number of households paying the licence fee.
“I simply think I’m in a place where I can work to improve dramatically the BBC and lead it in the right way,” he said. “We will make mistakes, but I think as a leadership, and myself, I’ve been very clear – and I think we have been decisive.
“When you go through tough times, one of the things that I focus on as a leader is there has never been a more important time for public service broadcasting. Gaza has been the most challenging editorial issue I’ve had to deal with. But the importance of fair, balanced reporting, the need for high-quality homegrown programming in the face of massive pressure, has never, ever been greater.
“I believe my leadership and the team I’ve assembled can really help the BBC thrive in that environment.”
Davie said the BBC had “already seen dismissals” as a result of an action plan drawn up after a series of scandals around conduct, including the Edwards scandal. The former presenter ultimately pleaded guilty to three counts of making indecent images of children. Neither Davie nor Samir Shah, the chair of the BBC, would name any individuals who had lost their jobs.
Davie said action was also being taken against senior figures involved in the Gaza failing and the livetreaming of Bob Vylan at Glastonbury. Pascal Robinson-Foster, who goes by the name Bobby Vylan as part of the duo, was shown leading chants of “death, death to the IDF”, referring to the Israel Defense Forces.
Davie faces another difficult decision over the future of the latest series of MasterChef, which has already been delivered to the BBC and in which Wallace features almost throughout. The decision has become even more difficult after the show’s other presenter, John Torode, announced he was the subject of an allegation of using racist language. He denies the incident happened.
Davie said MasterChef’s producer, Banijay, had to “follow up” on the allegation and report back to the BBC. He said he had made no decision over the series but was concerned about the effort put in by the amateur chefs involved.
“One of my overwhelming concerns is that we’ve got all the amateur chefs that gave their heart and soul to this programme,” he said. “We have to reflect on that, talk to them – and I’m sure Banijay are doing that – consult them, think about the audience, and then make a call. That’s what we’re going through now.”
He said there was a future for the show. “A great programme that’s well loved by audiences is much bigger than individuals,” he said.
The BBC’s annual report highlighted the strengths and serious challenges the BBC faces as streaming and YouTube continue to split audiences. The BBC is still managing to reach 94% of UK adults every month, while its digital platform iPlayer was the UK’s fastest-growing long-form on-demand service last year.
However, the number of households paying the BBC licence fee fell for a seventh consecutive year, down 300,000, the report stated.
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John Torode sacked as MasterChef presenter after racist language claim upheld
John Torode has been sacked as MasterChef presenter after an allegation against him using “an extremely offensive racist term” was upheld.
On Monday, the TV chef said he had “no recollection” of the incident, adding: “I do not believe that it happened.”
But in a statement on Tuesday, the show’s production company Banijay UK said it and the BBC “are agreed” that his contract on the show will not be renewed.
It plunges the BBC cooking show into a deeper crisis, after more than 40 separate allegations against Torode’s co-host Gregg Wallace were also upheld as part of an inquiry into his conduct.
The controversy over MasterChef started last year, when BBC News first revealed claims of inappropriate sexual language against Wallace.
Wallace was sacked last week as dozens more people came forward to BBC News with allegations against him. He has always denied the claims.
A BBC spokesperson said: “John Torode has identified himself as having an upheld allegation of using racist language against him.
“This allegation – which involves an extremely offensive racist term being used in the workplace – was investigated and substantiated by the independent investigation led by the law firm, Lewis Silkin.
“John Torode denies the allegation. He has stated he has no recollection of the alleged incident and does not believe that it happened. He also says that any racial language is wholly unacceptable in any environment.
“The BBC takes this upheld finding extremely seriously. We will not tolerate racist language of any kind and, as we have already said, we told Banijay UK, the makers of MasterChef, that action must be taken. John Torode’s contract on MasterChef will not be renewed.”
Speaking to BBC News, BBC director general Tim Davie described the allegation against Torode as “a serious racist term which does not get to be acceptable in any way shape or form”.
“It’s really important we are taking this seriously,” he said. “We’ve drawn a line in the sand”.
Davie wouldn’t be drawn on how much recent BBC controversies, from MasterChef to the failures over its Gaza documentary, to Bob Vylan’s set at Glastonbury, have cost licence fee payers.
“I’m not minimising the damage,” he said, “of when you make mistakes of this nature.”
But he added: “How we manage them and how we lead our way through it is how you build trust.”
Earlier on Tuesday, Mr Davie told a press conference that the Masterchef “absolutely” has a future, adding that it was “much bigger than individuals”.
But he refused to say what would happen to the unseen series – which was filmed last year, with both Wallace and Torode in it.
In an Instagram post on Monday, Torode revealed he was the subject of an allegation of using racist language, upheld as part of an inquiry into separate allegations against Wallace.
He said the allegation was that he made the remarks in a social setting in 2018 or 2019.
He added that the allegation included that the “person I was speaking with did not believe that it was intended in a malicious way and that I apologised immediately afterwards”.
Torode added: “I want to be clear that I’ve always had the view that any racial language is wholly unacceptable in any environment. I’m shocked and saddened by the allegation as I would never wish to cause anyone any offence.”
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Secrets of rhino evolution found in 20-million-year-old tooth
A fossilized rhino tooth, buried for over 20 million years, is now helping scientists rewrite the history of early rhino evolution.
Inside the tooth enamel, researchers found something remarkable: preserved proteins that held clues to the animal’s lineage and evolutionary split from other species.
This breakthrough came from scientists at the University of York. By analyzing enamel proteins in the tooth, the experts traced key moments in rhino evolution much further back than previously possible.
Reconstructing the rhino family tree
The team discovered that this particular rhino diverged from other members of the family Rhinocerotidae during a window between 41 and 25 million years ago. This coincides with a time between the Middle Eocene and Oligocene Epochs.
Even more surprising was that the data revealed that the two main subfamilies of rhinos – Elasmotheriinae and Rhinocerotinae – split later than previously thought.
Instead of parting ways in the Eocene, as earlier bone studies suggested, this separation likely occurred during the Oligocene, between 34 and 22 million years ago.
This new timeline helps scientists better understand how different rhino species emerged, adapted, and survived (or didn’t) through changing environments.
Rhino evolution revealed in DNA
Ancient DNA has helped researchers study extinct species, but it rarely survives beyond a million years. This fossil tooth changes that.
The successful recovery of enamel proteins from a sample over 20 million years old extends the timeline for molecular research by a factor of ten.
This is important because it allows scientists to explore evolutionary history through molecular evidence – not just fossil shapes. Well-preserved enamel proteins offer access to valuable genetic information, opening new avenues for discovery.
Enamel is the hardest tissue in the body. Its mineral-rich structure protects proteins for millions of years, especially in cold environments where this tooth was found.
Keeping the fossil tooth data pure
The fossil tooth was found in Canada’s High Arctic – a region where permafrost still dominates. That cold environment played a key role in keeping the proteins intact, but cold alone wasn’t enough.
To make sure the proteins were truly ancient, researchers at the University of York ran tests using a method called chiral amino acid analysis.
This technique helped the team distinguish between original proteins from the rhino’s life and any later contamination.
By comparing the degraded proteins in this tooth with those from previously studied rhino fossils, they confirmed the material was genuine.
Unique environmental history of the site
Professor Enrico Cappellini from the University of Copenhagen’s Globe Institute emphasized the significance of the fossil site.
“The Haughton Crater may be a truly special place for palaeontology: a biomolecular vault protecting proteins from decay over vast geological timescales,” said Cappellini.
“Its unique environmental history has created a site with exceptional preservation of ancient biomolecules, akin to how certain sites preserve soft tissues. This finding should encourage more paleontological fieldwork in regions around the world.”
Exploring further back in time
Dr. Marc Dickinson, a postdoctoral researcher at the University of York’s Department of Chemistry, was one of the co-authors on the study.
“It is phenomenal that these tools are enabling us to explore further and further back in time. Building on our knowledge of ancient proteins, we can now start asking fascinating new questions about the evolution of ancient life on our planet,” said Dickinson.
The team sees this fossil tooth as more than just an isolated find. It’s a signal that there may be more ancient biomolecules waiting to be studied.
New perspective on rhino evolution
“Successful analysis of ancient proteins from such an old sample gives a fresh perspective to scientists around the globe who already have incredible fossils in their collections. This important fossil helps us to understand our ancient past,” said Fazeelah Munir, who analyzed the tooth during her doctoral research at York.
Modern rhinos are threatened by habitat loss, poaching, and climate change. Tracing their evolutionary history reveals how past environmental shifts shaped the species we see today.
The more we understand what helped ancient rhinos survive – or led to their decline – the better equipped we are to protect the few that remain.
The full study was published in the journal Nature.
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