- 5 Israeli Soldiers Killed in Gaza, Military Says The New York Times
- LIVE: Israel kills 49 Palestinians in Gaza in 24 hours Al Jazeera
- 5 IDF soldiers killed, 14 injured by roadside bomb in northern Gaza The Times of Israel
- Five IDF Soldiers Killed, 14 Wounded in Northern Gaza Operation Haaretz
- Five Israeli soldiers killed in Gaza: military Arab News
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5 Israeli Soldiers Killed in Gaza, Military Says – The New York Times
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Role of reduction in acetyl CoA and pyruvate contents
6-PPD quinone at environmentally relevant concentrations disrupts citric acid cycle in Caenorhabditis elegans: Role of reduction in acetyl CoA and pyruvate contents
6-PPD quinone at environmentally relevant concentrations disrupts citric acid cycle in Caenorhabditis elegans: Role of reduction in acetyl CoA and pyruvate contents
KNOXVILLE, TN, July 08, 2025 /24-7PressRelease/ — Researchers explore how 6-PPD quinone (6-PPDQ), an environmental contaminant derived from tire antioxidant N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD), affects the citric acid cycle in C. elegans at environmentally relevant concentrations. The research reveals significant reduction in the citric acid cycle intermediates and key enzyme gene expressions by 6-PPDQ exposure, highlighting the its potential exposure risk on citric acid cycle metabolism.
6-PPDQ, has emerged as an environmental concern due to its widespread detection and toxic effects. In a study published in Environmental Chemistry and Ecotoxicology, researchers from Southeast University in China explored the effects of 6-PPDQ on the citric acid cycle and underlying mechanism in C. elegans. The citric acid cycle, a crucial metabolic pathway occurring in the mitochondria, plays a central role in cellular metabolism by linking carbohydrate, fat, and amino acid metabolisms. It provides intermediates for the synthesis of amino acids, fatty acids, and glycogen, which are essential for sustaining life activities.
The study reveals how 6-PPDQ at environmentally relevant concentrations (0.1–10 μg/L) disrupted the citric acid cycle by reducing intermediate metabolites, including citric acid, α-ketoglutarate, succinate, fumarate, malate, and oxaloacetate. Additionally, the reduction of these intermediate metabolites was due to the inhibition of relevant key enzyme gene expressions. Exposure to 6-PPDQ suppressed genes encoding citrate synthase (cts-1), isocitrate dehydrogenase 2 (idh-2), and α-ketoglutarate dehydrogenase complex (dlst-1, dld-1). As explained by the researchers, “exposure to 6-PPDQ significantly impacts the citric acid cycle in C. elegans, which is crucial for understanding the potential risks of this contaminant to both environmental and human health.”
The researchers also observed that 6-PPDQ exposure decreased acetyl CoA and pyruvate contents, which are important for the control of citric acid cycle. Acetyl CoA generated from pyruvate is a key substrate for the cycle. The study found that among the genes encoding components of the pyruvate dehydrogenase complex, which controls acetyl CoA synthesis, only dlat-1 and dld-1 expressions were decreased by 6-PPDQ. The expressions of genes pyk-1 and pyk-2 associated with pyruvate generation were also reduced. RNA interference (RNAi) of these genes further exacerbated the cycle’s disruption, highlighting the crucial contribution of these alterations to 6-PPDQ-induced toxicity.
The study also demonstrated that the disruption in citric acid cycle and reduction in acetyl CoA and pyruvate contents contributed to mitochondrial dysfunction, as indicated by increased oxygen consumption rates and decreased ATP content in 6-PPDQ exposed nematodes. Furthermore, the researchers investigated the protective effects of sodium pyruvate treatment, finding that it could suppress toxic effects of 6-PPDQ. “Our results suggest that sodium pyruvate treatment may be a promising approach to against 6-PPDQ toxicity,” the researchers concluded.
This study provides valuable insights into the mechanisms by which 6-PPDQ disrupts metabolic process of citric acid cycle and highlights the potential risks of this contaminant. The findings underscore the importance of further research to fully understand the implications of 6-PPDQ exposure for both environmental and human health.
References
DOI
10.1016/j.enceco.2025.05.022Original Source URL
https://doi.org/10.1016/j.enceco.2025.05.022Journal
Environmental Chemistry and EcotoxicologyChuanlink Innovations, where revolutionary ideas meet their true potential. Our name, rooted in the essence of transmission and connection, reflects our commitment to fostering innovation and facilitating the journey of ideas from inception to realization.
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Samsung Australia Wins Canstar Blue 2025 Innovation Excellence Award for its Glare-Free TV Technology – Samsung Newsroom Australia
Samsung’s Glare-Free TV display coating, validated by UL certification, lauded for “making OLED TVs far more versatile for use in bright environments.”
Samsung’s Glare-Free certified TV technology earns 2025 Innovation Excellence Award Winners – Home Entertainment. Pictured with Samsung OLED S95F (cables not shown).
Samsung Australia has today announced that Samsung Electronics’ Glare-Free certified TV display technology has won the prestigious 2025 Canstar Blue Innovation Excellence Award in Home Entertainment. In achieving this accolade, Canstar Blue judges deemed Samsung’s Glare-Free certified technology a “game-changing breakthrough” with the potential to improve the everyday lives of customers.
Unleashed across global markets in 2024 exclusively on the Samsung OLED S95D TV, Samsung’s Glare-Free certified technology uses an embossed coating to scatter ambient light in various angles and directions across wider diffusion patterns[1]. The result reduces on-screen reflections while maintaining the incredible brightness, object sharpness, and colour accuracy Samsung OLED TVs are renown for.
Independently verified by leading applied safety science company, UL Solutions, the OLED S95D became the world’s first certified Glare-Free OLED television, capable of effectively reducing reflection and discomfort glare.[1]
According to Canstar Blue judges: “Samsung’s OLED Glare-Free technology, validated by UL certification, stands out for its innovation, making OLED TVs far more versatile for use in bright environments. The Samsung S95 was the first model to showcase this feature, highlighting advancements in OLED TV technology and reinforcing its position as a noteworthy option in the market. Specifically designed for bright Australian homes, it minimises screen glare while preserving brightness, colour accuracy, and picture detail.”
Due to the technology’s incredible effectiveness, Samsung has expanded the application of its Glare-Free certified technology across its wider Neo QLED and QLED TV and monitors line-ups, offering enhanced viewing experiences to more Australians who experience their Samsung displays in rooms with abundant natural light.
Samsung’s 2025 Glare-Free TV line-up includes the Samsung OLED S95F, Neo QLED 8K QN990F, Neo QLED 8K QN900F, Neo QLED QN90F, The Frame Pro, and The Frame[1]. Samsung has also applied its Glare-Free certified technology to select 2025 monitors including the Odyssey OLED G8, Odyssey OLED G6[2], and OLED Smart Monitor M9[1], providing Australians with a distraction free experience whether they are using their monitors for productivity, entertainment or game play.
“Samsung’s Glare-Free certified OLED technology reflects years of research, development and investment, setting a new benchmark for TV design and versatility in the Australian market,” said Phil Gaut, Director – Consumer Electronics, Samsung Australia. “By addressing the pervasive issue of glare, Samsung has redefined what consumers can expect from their televisions, combining cutting-edge technology with practical benefits to help enhance everyday living.”
Samsung currently also holds the title of Canstar Blue’s Most Satisfied Customers Award – TV, having achieved 5-star ratings across Performance, Durability, User friendliness, and Features & Functionality testing categories.
Samsung’s Bespoke AI Heat Pump Combo washer also earned a 2025 Canstar Blue Innovation Excellence Award in the Laundry Appliances category. The Bespoke AI Heat Pump Combo washer was commended for “its speed and energy ratings, offering improved efficiency and potential time savings compared to other models.”
For more information on Samsung’s 2025 Glare-Free TV line-up, visit: https://www.samsung.com/au/tvs/
For more information on Canstar Blue’s Innovation Excellence Awards, visit: https://www.canstarblue.com.au/awards/innovation-excellence/
[1] Glare Free: Reflection Glare UGR <10, Discomfort Glare UGR <22, Disability Glare UGR <34 by UL LLC. (UL Solutions), Certificate Number: V166045 – Exp. 31/12/2025
[2] Coming to Australia in the second half of 2025. Pricing and availability yet to be announced.
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Why did Orlando Bloom get his blood cleaned? – podcast | Science
The actor recently posted a photo of himself undergoing a £10,000 procedure at a London clinic that claims to remove microplastics, forever chemicals and herbicides from the blood. But how settled is the science around the health risks of microplastics? To find out, Ian Sample speaks to Dr Stephanie Wright, associate professor of environmental toxicology at Imperial College London’s school of public health. She explains what we know so far about the effects of microplastics in the body, why the science is still evolving, and what we can do to reduce our exposure
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How partners Beth Mead and Vivianne Miedema are dealing with their ‘inevitable’ clash
England vs Netherlands: Make or break for the Lionesses
As if Wednesday’s clash didn’t already have plenty riding on it, for the Lionesses it could be the difference between retaining their title and an early flight home.
Defeat to the Netherlands would seal their fate, pending a France victory against tournament debutants Wales.
While Sarina Wiegman’s side boast the better record in the history of this fixture, they need to be wary of Miedema, fresh off the back of becoming a Dutch centurion.
Her brilliant strike against Wales was her 100th for her national team and will no doubt give her even more confidence as the tournament progresses.
In a candid response to it, Mead says it will be the first and last goal of Miedema’s that she will be celebrating while at EURO 2025.
“I was sat watching so I cheered for her, but that’s the only time I’ll be cheering for her in the tournament,” she said.
“We won’t be speaking too much about football this week.”
Emotions will be mixed, tensions high, but for each of these players their focus will be on one thing only: helping their nation secure all three points.
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Your Daily Work Horoscope for July 08, 2025
Your Daily Work Horoscope for July 08, 2025. Discover your Daily Work Horoscope for each zodiac sign here.
Aries
Your diplomatic skills are at the forefront, and you’re in the right place at the right time to make a great impression on an important person. It could change the course of your career.
Taurus
Your emotions are larger than life. Don’t overreact. Try to focus on one issue at a time so you don’t get overwhelmed. If you’re struggling to multitask, back off. Things will calm down soon.
Gemini
You could encounter an opportunity that shouldn’t be deferred. Whatever you decide, go all the way. If you hedge your bets or try half measures, you’ll end up far behind the competition.
Cancer
Your social impulses are strong, and you’d love nothing more than to be in the middle of a crowd. It’s best, however, if you focus on one-on-one relationships. The intimacy will yield good results.
Leo
Try your best to adapt to the ever-changing facets of your life. Focusing on the details will help alleviate confusion and stress. Don’t get bogged down in negativity. It’s counterproductive.
Is your job fulfilling? Stay aligned with your Personalized Career Horoscope!
Virgo
Your brainpower is strong, and it’s stimulating quite a bit of energy and activity. Harness that drive and you’ll make unbelievable progress, especially when it comes to creative pursuits.
Libra
Listen to your intuition, or better yet, sit back and let it do the heavy lifting today. Relying on your self-will will only get you so far. If you trust your subconscious, you’ll get a lot more done in less time.
Scorpio
Offer some constructive advice to a coworker. You can see the problem clearly, but you might need to be as diplomatic as possible. That shouldn’t be a problem for you. You’re as tactful as they come.
Sagittarius
Inventory and asset tracking are important. Give it all a once-over and see what you learn. You could encounter many surprises, good and bad. Get your best people on the job.
Capricorn
Anything you start today should go well for you. That’s why it’s a great time to tackle new projects or even fish around for new jobs or career paths. Maybe see about going back to school.
Aquarius
This is a great time to go out on a limb, especially if you’re fishing for a new job, promotion, or raise. The right people will see you, and if the timing is right you’ll be on your way to the top.
Pisces
You have a strong need to vent today. Make sure you have a sympathetic ear waiting to hear you out. Try to be careful not to start something that doesn’t need to be started.
Need a quick answer? Yes/No Tarot will offer guidance right now!
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Perfect trio of prehistoric atolls shine like tropical gems off Australian coast — Earth from space
QUICK FACTS
Where is it? Rowley Shoals, Australia [-17.32117355, 119.26473330]
What’s in the photo? From left to right; Imperieuse Reef, Clerke Reef and Mermaid Reef
Who took the photo? An unnamed astronaut on board the International Space Station
When was it taken? Oct. 18, 2011
This striking astronaut photo shows a unique chain of three atolls lined up side-by-side off the coast of Australia. The oval islands were once part of a colossal coral system that rivaled the Great Barrier Reef.
The trio of islands makes up Rowley Shoals, an uninhabited Australian territory located in the Timor Sea around 180 miles (290 kilometers) off the coast of Western Australia. From southwest to northeast (left to right), the islands are named Imperieuse Reef, Clerke Reef and Mermaid Reef.
The egg-shaped structures are all atolls — rings of land built from fringing coral reefs that once circled an island that has subsequently sunk beneath the waves. These atolls are evenly spaced out into a near-perfect straight line spanning roughly 60 miles (100 km) from end to end, according to NASA’s Earth Observatory.
Each island has a surface area of around 30 square miles (80 square km). Only Imperieuse Reef and Clerke Reef have white sandy islets, or cays, that remain above water. Imperieuse Reef also has the only permanent human-made structure in Rowley Shoals — a lighthouse.
The atolls sit on one of the largest continental shelves on Earth. Around 10 million years ago, this area was home to a massive barrier reef system spanning more than 1,250 miles (2,000 km), which later fell into the sea due to tectonic subduction.
The atolls are believed to be some of the last remnants of this lost ecosystem, along with Ningaloo Reef, the Ashmore and Cartier Islands and the Scott and Seringapatam Reefs, according to a study published in February 2025.
Related: See all the best images of Earth from space
Tourism to Rowley Shoals is now mainly limited to scuba diving following decades of mismanagement. (Image credit: Explore Parks WA) The collective ecosystems of Rowley Shoals experienced a massive decline in the 1970s when the islands became popular with tourists and started hosting deep-sea fishing expeditions.
As a result, the area is now protected by two marine reserves: Rowley Shoals Marine Park, which contains Imperieuse Reef and Clerke Reef; and Mermaid Reef Marine Park, which protects Mermaid Reef and its surrounding waters. This has helped the respective ecosystems to recover to pre-tourism levels.
Today, the atolls are home to a wide variety of marine life, including sea turtles, reef sharks and giant clams, as well as around 900 other species of fish, mollusks and corals, according to the Atlas of Living Australia.
Rowley Shoals is currently listed as one of the best places to go scuba diving in Australia, outside of the Great Barrier Reef, according to the Professional Association of Diving Instructors (PADI). However, the atolls’ diving season is limited to between September and December to help minimize the impacts of these visitors.
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Financing the Future of Sustainable Agriculture in Brazil’s Cerrado – Reflections from London Climate Action Week 2025
The Soft Commodities Forum (SCF) and its partners from Tropical Forrest Alliance, IDH, Olab, Proforest, Responsible Commodities Facility, Sustainable Investment Management, The Consumer Goods Forum – Forest Positive Coalition, and WWF, had a strong presence at London Climate Action Week 2025, standing out amid the high energy and packed rooms focused on Brazil’s critical role in global climate and food system solutions. From regenerative agriculture to forest conservation, support was loud and clear for the urgent need to scale-up holistic, landscape-scale approaches – many of which were on display throughout the week.
As part of the week’s events the Sustainable Landscapes Partnership (SLP), a joint initiative between
tThe Consumer Goods Forum’s Forest Positive Coalition (CGF-FPC) and the World Business Council for Sustainable Development’s Soft Commodities Forum (WBCSD-SCF) – organized a session with partners on Transition Finance for Resilient Agricultural Systems. The session aimed to place the spotlight on Brazil’s Cerrado biome, engaging a diverse array of stakeholders, focusing on a highly pressing question:How can finance accelerate the shift toward sustainable, deforestation- and conversion-free (DCF) agriculture in one of the world’s most ecologically critical and agriculturally productive regions?
The Sustainable Landscapes Partnership is a collaboration between the WBCSD SCF and CGF FPC to advance sustainable soy production
landscapes in high risk areas of the Brazilian CerradoThe session included interventions from leading programs advancing sustainable agriculture and land-use across the Cerrado, including the Responsible Commodities Facility (RCF), Agri3, WWF, IDH and others. At the heart of these discussions was a shared concern: Supporting the Cerrado’s continued growth as a vital agricultural hub is essential for food security and rural livelihoods. It is of critical importance to protect its unique and irreplaceable ecosystems, which make up a global biodiversity hotspot, a major carbon sink, and a source of drinking water and hydropower for millions of Brazilians.
The SLP is a key piece in a constellation of complementary solutions. Recognizing that isolated efforts aren’t enough, the SLP brings together value chain actors behind a shared vision for resilient, DCF landscapes. To date, the partnership has mobilized nearly $10 million in joint investment (plus $2.4 million leveraged), supported improved livelihoods on 700+ farms, and advanced climate and nature outcomes across 800,000 hectares. Now, in a crucial moment of expansion, the partnership is seeking $10 million in near-term co-funding and over $10 million annually in sustained, blended capital to scale impact. With multiple pathways to engage, the message is clear: this model works – now is the time to scale it up for an even larger impact.
Co‑organizers have been advancing sustainable production landscapes and value chains in the Brazilian Cerrado, supported by pioneering initiatives and investors. The event at LCAW became an open forum for lessons learned, benefits, and challenges facing producers and financiers, highlighting collaborative projects that are strengthening productive, traceable and sustainable landscapes in the Cerrado.
There were two engaging panel discussions as part of the session. On the first panel, COFCO International represented the Soft Commodities Forum by introducing the SLP as a unique model of value-chain collaboration in a room largely focused on finance. They shared how the program has evolved from early-stage grant funding, combining flagship pilot programs under the SCF’s Farmer First Clusters and parallel investments by downstream members of the CGF-FPC, towards a scalable vision for long-term sustainable finance, setting a clear path forward for transformative landscape investment.
The SLP is charting a path towards scale up evolving from a grant funded model towards sustainable models of investment and financing A second panel included perspectives from financial stakeholders such as Rabobank, Agri3 Fund and more. CGF-FPC member Sainsburys brought the retailer perspective to the panel, articulating the value proposition for improving supply chain resilience and investing directly in sustainable solutions at the source of goods that end up on their shelves.
It was a high-energy session oriented towards understanding solutions, implementation gaps and facilitating matchmaking across stakeholders to accelerate collective solutions in the Cerrado. It certainly helped that it was held high atop the famous Gherkin, a spectacular backdrop for an important dialogue.
CGF FPCs Transition Finance for Resilient Agricultural Systems session at the Gherkin in London Building a Scalable Long-term Financial Model
A key theme during LCAW, and particularly during the CGF-FPC session, was the shift from short-term grant funding to long-term, scalable financing models. While public and philanthropic capital remain essential for early-stage support and risk mitigation, participants emphasized the need for innovative financing mechanisms that can attract investment into sustainable landscapes. This includes blended finance models that combine grants, technical assistance, and patient capital to support producers and project developers.
An exciting announcement came from the Brazilian Treasury about their newly renamed “Caminho Verde” or Green Way program which aims to channel public funds into highly subsidized loans for regenerating degraded pastures, a top lever for advancing regenerative agriculture, while reducing pressure for land-clearing by utilizing long-cleared land. SCF and partners will look for opportunities to access this funding to expand our impact in this area, which is already part of ”the smart mix” of solutions under the SLP and a top priority for the Brazilian government.
Aligning the Value Chain
Speakers stressed the importance of value‑chain alignment, from upstream producers to downstream offtakers and retailers. Efforts to promote traceability – particularly for indirect suppliers, harmonize risk methodologies and reporting, and align incentives are essential to building transparent DCF supply chains across the Cerrado and beyond.
The Soft Commodities Forum and the Forest Positive Coalition continue to collaborate on these strategic points. During LCAW members of both groups held a closed‑door session to deepen coordination on DCF sourcing and reporting – covering indirect supply chains and municipal‑level risk assessment – and to advance joint landscape investments in the Cerrado’s highest‑risk areas, maximizing shared resources and impact under the SLP.
A Call for Collective Action
Systemic change cannot be achieved by any one actor alone. Building resilient landscapes and sustainable food systems demands stronger collaboration across corporates, investors, governments, and civil society. While a single solution may not exist, a clear message from the week was the need to better articulate the purpose behind each initiative, align efforts with the right types of funders and investors, and, where possible, coordinate or even integrate approaches to amplify impact and unlock greater investment.
The SLP remains a vital platform for collective action on DCF soy production in the Cerrado – aligning stakeholders and methods, mobilizing capital, and driving progress toward a future where agriculture supports both people and planet.
Interested in learning more about the SLP and its impacts in the Cerrado and future opportunities to scale up? Please reach out to Debora Dias (d.dias@theconsumergoodsforum.com) or Matt Inbusch (inbusch@wbcsd.org) for more information on how you can get involved.
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5 IDF soldiers killed, 14 injured by roadside bomb in northern Gaza – The Times of Israel
- 5 IDF soldiers killed, 14 injured by roadside bomb in northern Gaza The Times of Israel
- Five Israeli soldiers killed in Gaza as pressure mounts for ceasefire Al Jazeera
- Militants kill 5 Israeli soldiers in Gaza and Israeli strikes kill 51 Palestinians Herald Bulletin
- Five IDF Soldiers Killed, 14 Wounded in Northern Gaza Operation Haaretz
- IDF faces challenges in Beit Hanun, terrorists persist despite efforts The Jerusalem Post
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Pakistan: Authorities seize 18 lions kept as pets
Pakistani authorities confiscated eighteen lions kept illegally as pets in the densely populated Punjab region during a targeted operation, provincial officials said Monday.Authorities launched a crackdown after a lion escaped from a house in Lahore, the capital of Punjab province, and attacked a woman and two children. The incident, which took place last week, was captured on video.None of the people suffered life-threatening injuries, according to provincial officials. The lion, which was kept without a license in a house in Lahore, was confiscated.The lion was sent to a local safari park, according to Mubeen Elahi, director general of the provincial Wildlife and Parks Department. Police said the owner was arrested.
Keeping big pets considered a status symbol
Keeping a lion at home without following the legal requirements for ownership of big cats is an offense punishable by up to seven years in jail, Elahi told the Reuters news agency.As well as confiscating the 18 animals, the department raided 38 lion and tiger breeding farms and arrested eight people for violating the rules, he said.There are more than 500 lions and tigers in homes and breeding farms in Punjab, Elahi said, adding they would be inspected by the end of the week.Keeping exotic animals is considered a status symbol among some wealthy Pakistanis, despite the high fees associated with ownership.
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