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  • AI-Powered Universal Strategy for Protein Engineering Unveiled

    AI-Powered Universal Strategy for Protein Engineering Unveiled

    A team of Chinese researchers led by Prof. GAO Caixia from the Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy of Sciences has developed a groundbreaking method that could transform the field of protein engineering. The new approach, called AI-informed Constraints for protein Engineering (AiCE), enables rapid and efficient protein evolution by integrating structural and evolutionary constraints into a generic inverse folding model—without the need to train specialized artificial intelligence (AI) models.

    The study, published in Cell on July 7, addresses many of the challenges associated with traditional protein engineering techniques.

    The ideal protein engineering strategy would achieve optimal performance with minimal effort. However, existing approaches are often limited in terms of cost, efficiency, and scalability. Current AI-based protein engineering methods are often computationally intensive, underscoring the need for more accessible and user-friendly alternatives that preserve predictive accuracy and enable broader adoption across the research community.

    In this study, the researchers first developed AiCEsingle, a module designed to predict high-fitness (HF) single amino acid substitutions. It enhances prediction accuracy by extensively sampling inverse folding models—AI models that generate compatible amino acid sequences based on protein 3D structures—while incorporating structural constraints.

    Benchmarking against 60 deep mutational scanning (DMS) datasets demonstrated that AiCEsingle outperforms other AI-based methods by 36–90%. Its effectiveness for complex proteins and protein–nucleic acid complexes was also validated. Notably, incorporating structural constraints alone yielded a 37% improvement in accuracy.

    To address the challenge of negative epistatic interactions in combinatorial mutations, the researchers developed the AiCEmulti module, which integrates evolutionary coupling constraints. This allows for accurate prediction of multiple high-fitness mutations at minimal computational cost, expanding the tool’s versatility and practical utility.

    Using the AiCE framework, the researchers successfully evolved eight proteins with diverse structures and functions, including deaminases, nuclear localization sequences, nucleases, and reverse transcriptases. These engineered proteins have enabled the creation of several next-generation base editors for applications in precision medicine and molecular breeding. These include: enABE8e, a cytosine base editor with a ~50% narrower editing window; enSdd6-CBE, an adenine base editor with 1.3× higher fidelity; and enDdd1-DdCBE, a mitochondrial base editor showing a 13× increase in activity.

    AiCE represents a simple, efficient and broadly applicable strategy for protein engineering. By unlocking the potential of existing AI models, it offers a promising new direction for the field and enhances the interpretability of AI-driven protein redesign.

    /Public Release. This material from the originating organization/author(s) might be of the point-in-time nature, and edited for clarity, style and length. Mirage.News does not take institutional positions or sides, and all views, positions, and conclusions expressed herein are solely those of the author(s).View in full here.

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  • See a rare dinosaur or a chunk of Mars during Sotheby’s ‘Geek Week’

    See a rare dinosaur or a chunk of Mars during Sotheby’s ‘Geek Week’

    New Yorkers may not think of Sotheby’s, the tony auction house on the Upper East Side, as a place to casually pop in to, let alone a place to see dinosaurs or Martian meteorites.

    But during “Geek Week,” that’s exactly what’s on free public view. From July 8 to 15, Sotheby’s is displaying some remarkable objects of natural history, science and space exploration before they hit the auction block.

    This year’s standout is a six-foot-tall, 10-foot-long juvenile Ceratosaurus, one of only four known specimens of this extremely rare Jurassic dinosaur.

    The roughly 150 million-year-old fossil, which has been reconstructed with a few ceramic elements to replace missing pieces, was discovered in Wyoming in 1996, according to Cassandra Hatton, Sotheby’s vice chairman of science and natural history.

    It’s expected to sell for between 4 and 6 million dollars.

    The sale includes more than 100 ancient items, sourced from various collectors, including dinosaur skulls and claws, chunks of meteorites, a 4,000-year-old stone axe and astonishing, iridescent slices of mineral and crystal, all on view.

    Another showstopper is a 54-pound Martian meteorite – the largest known piece of Mars on Earth. This chunk of the Red Planet is believed to have been chipped off by one of only 16 known asteroid strikes powerful enough to launch debris into space, before landing in the Sahara desert.

    “That chunk had to be loose enough to break off, and then it had to get on the right trajectory to travel 140 million miles to Earth, and then it had to land in a spot where someone could find it,” Hatton said. “And then we were lucky enough that someone came by who knew enough about meteorites to recognize that it wasn’t just a big rock.”

    Hatton said scientists were able to confirm the meteorite’s extraterrestrial origin by extracting gas trapped in bubbles inside the rock and comparing it to Martian atmospheric data transmitted from NASA’s Viking lander in 1976.

    The sale also includes objects that went to space with astronaut Buzz Aldrin, from his collection.

    Another highlight includes what Hatton describes as the finest operational Apple-1 computer in existence: one of 50 machines hand-built by Steve Wozniak and Steve Jobs in 1976.

    The Apple founders had built a few prototypes and were shopping them around town, Hatton said, when a local shopkeeper happened to see their presentation at the Home Brew Computer Club, an early computer hobbyist group in Menlo Park, California. He asked for 50, which sent the techies scrambling for parts to fulfill a bigger order than they’d anticipated.

    The sale also includes one of Jobs’ earliest business cards, expected to sell for $5,000 to 8,000.

    For those who associate Sotheby’s with high-stakes blue-chip art sales and exclusivity, Geek Week is a reminder that the auction house doubles as a pop-up museum.

    Hatton said she’s the only science specialist on staff.

    “I go from scientific books and manuscripts to tech, dinosaurs, minerals, meteorites, space exploration,” Hatton said. “I do hip-hop sales sometimes too. It all connects together somehow, in my mind.”

    Sotheby’s Geek Week is at 1334 York Ave. from July 8 through 15, open from 10 a.m. to 5 p.m. every day except Sunday, when it opens at 1 p.m. No RSVP is required.

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  • Common bacteria found in the stomach has no symptoms but could cause 12 million cancers, study warns

    Common bacteria found in the stomach has no symptoms but could cause 12 million cancers, study warns

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    A common bacteria found in the stomach could cause nearly 12 million cancers among people born over a single decade, a new study suggests.

    Over the course of their lives, 15.6 million people born between 2008 and 2017 are expected to develop stomach cancer – and 76 per cent may be caused by the Helicobacter pylori bacteria, according to the study published in the journal Nature Medicine.

    Stomach cancer is largely preventable, but the prognosis is poor once a patient is diagnosed. It is the fifth most common form of cancer worldwide, killing an estimated 770,000 people per year.

    Chronic infection with H. pylori is a major cause, and it helps explain the rise in stomach cancers among young people in recent years, the study found.

    Most people are infected with H. pylori as children, and they may be infected for years without knowing it because the infection doesn’t cause symptoms. But it can also cause ulcers or inflammation in the stomach lining.

    The bacteria can spread by mouth, for example kissing, or through contact with vomit or stool.

    Where stomach cancer cases will rise

    Researchers from the World Health Organization’s (WHO) cancer research agency analysed stomach cancer data from 185 countries in 2022.

    They projected that under current trends, 11.9 million people could be diagnosed with stomach cancer attributable to H. pylori infection by 2101, which is the year someone born in 2017 would turn 84.

    The vast majority of bacteria-linked stomach cancer cases – 8 million – are expected in Asia. Another nearly 471,000 cases are projected in the European Union, the United Kingdom, Switzerland, Norway and Iceland.

    The burden of stomach cancer is also shifting globally. While sub-Saharan Africa currently has relatively few cases, the researchers expect stomach cancer cases tied to H. pylori to rise to 1.4 million by 2101 – six times higher than the rate in 2022 – due to ageing and population changes.

    “With demographic changes set to increase the gastric cancer burden in many parts of the world, there is an urgent need for coordinated prevention strategies and for regional health systems to be prepared to manage the growing burden,” said Dr Jin Young Park, one of the study’s co-authors and head of the gastric cancer prevention team at the WHO’s International Agency for Research on Cancer (IARC).

    The study has some limitations, notably poor data quality in lower-income countries that can make it harder to make confident predictions.

    But the researchers said the data is clear enough for health authorities around the world to take action.

    They called for countries to invest in initiatives to screen and quickly treat people for H. pylori infection. Their analysis shows that such programmes could reduce the number of expected stomach cancer cases by up to 75 per cent.

    “It is essential that health authorities make gastric cancer prevention a priority and accelerate efforts to control it,” Park said.

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  • NASA’s Hubble and Webb Telescopes Reveal Two Faces of a Star Cluster Duo

    NASA’s Hubble and Webb Telescopes Reveal Two Faces of a Star Cluster Duo

    A riotous expanse of gas, dust, and stars stake out the dazzling territory of a duo of star clusters in this combined image from NASA’s Hubble and Webb space telescopes.

    Open clusters NGC 460 and NGC 456 reside in the Small Magellanic Cloud, a dwarf galaxy orbiting the Milky Way. Open clusters consist of anywhere from a few dozen to a few thousand young stars loosely bound together by gravity. These particular clusters are part of an extensive complex of star clusters and nebulae that are likely linked to one another. As clouds of gas collapse, stars are born. These young, hot stars expel intense stellar winds that shape the nebulae around them, carving out the clouds and triggering other collapses, which in turn give rise to more stars.

    In these images, Hubble’s view captures the glowing, ionized gas as stellar radiation blows “bubbles” in the clouds of gas and dust (blue), while Webb’s infrared vision highlights the clumps and delicate filamentary structures of dust (red). In Hubble images, dust is often seen silhouetted against and blocking light, but in Webb’s view, the dust – warmed by starlight – shines with its own infrared glow. This mixture of gas and dust between the universe’s stars is known as the interstellar medium.

    The nodules visible in these images are scenes of active star formation, with stars ranging from just one to 10 million years old. In contrast, our Sun is 4.5 billion years old. The region that holds these clusters, known as the N83-84-85 complex, is home to multiple, rare O-type stars, hot and extremely massive stars that burn hydrogen like our Sun. Astronomers estimate there are only around 20,000 O-type stars among the approximately 400 billion stars in the Milky Way.

    The Small Magellanic Cloud is of great interest to researchers because it is less enriched in metals than the Milky Way. Astronomers call all elements heavier than hydrogen and helium – that is, with more than two protons in the atom’s nucleus – “metals.”  This state mimics conditions in the early universe, so the Small Magellanic Cloud provides a relatively nearby laboratory to explore theories about star formation and the interstellar medium at early stages of cosmic history. With these observations of NGC 460 and NGC 456, researchers intend to study how gas flows in the region converge or divide; refine the collision history between the Small Magellanic Cloud and its fellow dwarf galaxy, the Large Magellanic Cloud; examine how bursts of star formation occur in such gravitational interactions between galaxies; and better understand the interstellar medium.

    Explore More

    Media Contact:

    Claire Andreoli
    NASA’s Goddard Space Flight CenterGreenbelt, MD
    claire.andreoli@nasa.gov

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  • India U19 Vs England U19 LIVE Score: India Eye Wickets As 1-Down England Gain Momentum In Chase – NDTV Sports

    India U19 Vs England U19 LIVE Score: India Eye Wickets As 1-Down England Gain Momentum In Chase – NDTV Sports

    1. India U19 Vs England U19 LIVE Score: India Eye Wickets As 1-Down England Gain Momentum In Chase  NDTV Sports
    2. ENG vs IND 2nd Test Day 3 session timings, England vs India live streaming  Business Standard
    3. ENG vs IND: Watch Vaibhav Suryavanshi In Action — Time, Venue & Live Streaming Details  ABP Live English
    4. IND U19 vs ENG U19 LIVE Cricket Score, 5th ODI: England win by 7 wickets as India seal series 3-2  The Indian Express
    5. ENG U-19 vs IND U-19 Live Streaming Info, 5th ODI: When and where to watch India U-19 tour of England 2025; match details, squads  Sportstar

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  • How solar power helped European grids pass ‘the stress test’ during the recent heatwave

    How solar power helped European grids pass ‘the stress test’ during the recent heatwave

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    Europe’s latest heatwave dialled up daily power demand by up to 14 per cent, as Europeans turned up their air conditioning to stay cool.

    But the sunshine also increased the availability of solar energy, the same analysis from energy think tank Ember shows, helping Europe’s power grids pass “the stress test” of extreme heat. 

    Between 28 June and 2 July, peak daily temperatures averaged out at 35°C in Germany and Spain – where some local temperatures crossed 40°C – and 34°C in France. 

    As a result of soaring air con use, daily power demand soared by up to 14 per cent in Spain, 9 per cent in France, and 6 per cent in Germany, compared to the previous week.

    “Despite the huge pressure, European grids passed the stress test, and solar electricity played a major role in keeping them running,” says Pawel Czyzak, Europe Programme Director at Ember.

    How did solar energy help get Europe through the heatwave?

    June 2025 saw the highest EU solar generation on record at 45 terrawatt hours (TWh), a 22 per cent increase from the year before. This flooded grids with cheap, clean electricity during daytime hours.

    In the peak days of the heatwave, solar delivered up to 50 gigawatts (GW) of power in Germany, generating 33-39 per cent of the country’s electricity.

    By contrast, thermal power plants struggled in the heat. In France, 17 out of 18 nuclear power plants faced capacity reductions during the heatwave, with some shut down completely due to high river temperatures which meant their waters couldn’t be used as usual to cool the reactors. 

    The Beznau nuclear power plant in Switzerland also had its capacity halved as the River Aare crept up to 25°C – a decision taken to protect the ecosystem. 

    In Poland – where there are long-running concerns about the cooling of coal power plants – the government and grid operator PSE proposed an ‘anti-blackout package’ at the peak of the heatwave on 2 July.

    Other parts of power systems also struggle during the heatwaves. The overheating of cables is the likely cause of power outages in Italy on 1 July, Ember notes.

    The heatwave triggered a spike in electricity prices

    “The surplus of solar energy during the day helped prevent blackouts,” says Czyzak. “However, the use of energy storage is still insufficient, leading to reduced energy supply after sunset. This translated into a sharp increase in electricity prices.”

    According to Ember’s analysis, this supply-demand imbalance caused average daily power prices to double or even triple in some countries. 

    Between 24 June 24 and 1 July, average daily electricity prices rocketed by 175 per cent in Germany, 108 per cent in France, 106 per cent in Poland, and 15 per cent in Spain. During the evening peak on 1 July, prices spiked above €470/MWh in Poland and €400/MWh in Germany. 

    Interconnectors – cables used to connect the electricity systems of neighbouring countries – ensured these price spikes dissipated quickly, Ember explains. 

    As the heatwave swept across Europe, peaking in Madrid on Sunday 29 June, Paris on Tuesday 1 July, and Berlin and Warsaw on Wednesday 3 July, interconnectors helped deliver electricity to where it was needed most.

    Solar electricity storage and renewable ‘energy islands’

    But the continent’s power infrastructure still needs a serious upgrade to cope with increasingly severe heatwaves due to climate change

    Greater battery storage is needed to spread out the variable energy that solar and wind produce, Ember says. And better demand flexibility – i.e. shifting non-critical demand to periods of abundant supply – will help ease peak stress on the grid.

    “Perhaps the biggest opportunity is to store solar electricity, to help power air conditioning well into the evening,” says Czyzak.

    The experts are also calling for more investment in distributed energy sources capable of starting the network on their own, such as solar farms with grid-forming inverters. Unlike traditional grid-following inverters that only sync with the existing grid, these inverters can start without an external voltage supply. 

    A recent project by the UK National Energy System Operator (NESO) showed the potential of this solution, exploring how wind and solar could be used to restart the grid after a blackout. It recommended building renewables-powered energy islands that are later joined to the whole grid. 

    Belgium’s transmission system operator is testing grid-forming assets too. It’s all part of the global goal to triple renewable energy capacity by 2030, a measure to mitigate the climate crisis – and the increasing heatwaves it is bringing.

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  • New Intel Core Ultra gaming CPUs rumored to boost clock speeds, arrive this year

    New Intel Core Ultra gaming CPUs rumored to boost clock speeds, arrive this year

    Intel will launch a refreshed lineup of its Intel Core Ultra 200 CPUs later this year, with the chips based on a refreshed variant of the Intel Arrow Lake architecture that powers its current flagship gaming CPUs, according to a new report. These so-called Intel Arrow Lake refresh chips are expected to come with increases in clock speed as well as AI number crunching, for modest all-around gains in performance.

    The new Intel CPU lineup could help bolster the company’s efforts to attract gaming PC users to once again buy its chips, after several years of AMD’s X3D CPUs proving dominant in gaming performance and topping our best gaming CPU charts. However, the new report also suggests the performance gains will be modest, so this is far from a nailed-on certainty.

    The Intel Arrow Lake refresh data comes from ZDNet Korea, which according to a machine translated version of the page, states that “Intel is set to release ‘Arrow Lake Refresh’, a desktop PC processor that slightly improves the performance of its Core Ultra 200S processor, in the second half of this year.”

    The site doesn’t cite any source for this, so this is all just rumor for the time being. However, crucially, it goes on to say that “the prevailing opinion is that the performance improvement is not that great compared to the previous generation (14th generation, Raptor Lake Refresh).”

    In other words, while Intel may be bringing a little more general performance to the table with its Intel Arrow Lake refresh chips – expected to arrive with model names based on the Intel Core Ultra 200 schema – they won’t be expected to take either the general performance crown from the Intel Core i9-14900K or the gaming performance crown from the AMD Ryzen 7 9800X3D.

    Instead, the biggest boost is expected to be in AI. Intel’s current Core Ultra 200 desktop chips aren’t Microsoft CoPilot+ certified thanks to their AI-processing NPU not being quite powerful enough, so a slight increase would allow them to tick that box.

    For most gaming PC builders, though, it’s looking much more like future AMD Zen 6 CPUs will be the next big leap in gaming CPU performance. Though those aren’t expected to arrive until 2026.

    Meanwhile, despite its gaming performance not being chart-topping, our Intel Core Ultra 7 265K review shows Intel’s latest is still a very capable CPU. What’s more, recent price drops mean it’s currently far cheaper than the 9800X3D, at well under $300.

    Whatever model of CPU you’re rocking, if you’re looking to get the most from your system, a RAM upgrade could be ideal. If you’re stuck on 8GB or even 16GB, a move to 32GB could allow your system to spread its wings. Check out our best gaming RAM guide to find the best upgrade for your needs.

    You can also follow us on Google News for daily PC games news, reviews, and guides. We also have a vibrant community Discord server, where you can chat about this story with members of the team and fellow readers.

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  • Scientists Discover Giant Sand Bodies Beneath The North

    Scientists Discover Giant Sand Bodies Beneath The North

    Scientists have discovered hundreds of giant sand bodies beneath the North Sea that appear to defy fundamental geological principles and could have important implications for energy and carbon storage.

    Using high-resolution 3D seismic (sound wave) imaging, combined with data and rock samples from hundreds of wells, researchers from The University of Manchester in collaboration with industry, identified vast mounds of sand—some several kilometers wide—that appear to have sunk downward, displacing older, lighter and softer materials from beneath them.

    The result is stratigraphic inversion—a reversal of the usual geological order in which younger rocks are typically deposited on top of older ones—on a previously unseen scale.

    While stratigraphic inversion has previously been observed at small scales, the structures discovered by the Manchester team, now named “sinkites,” are the largest example of the phenomenon documented so far.

    The finding, published in the journal Communications Earth & Environment, challenges scientists understanding of the subsurface and could have implications for carbon storage.

    “This discovery reveals a geological process we haven’t seen before on this scale,” said lead author Professor Mads Huuse from The University of Manchester. “What we’ve found are structures where dense sand has sunk into lighter sediments that floated to the top of the sand, effectively flipping the conventional layers we’d expect to see and creating huge mounds beneath the sea.”

    It is believed the sinkites formed millions of years ago during the Late Miocene to Pliocene periods, when earthquakes or sudden shifts in underground pressure may have caused the sand to liquefy and sink downward through natural fractures in the seabed. This displaced the underlying, more porous but rigid, ooze rafts—composed largely of microscopic marine fossils—bound by shrinkage cracks, sending them floating upwards. The researchers have dubbed these lighter, uplifted features “floatites.”

    The finding could help scientists better predict where oil and gas might be trapped and where it’s safe to store carbon dioxide underground.

    “This research shows how fluids and sediments can move around in the Earth’s crust in unexpected ways. Understanding how these sinkites formed could significantly change how we assess underground reservoirs, sealing, and fluid migration—all of which are vital for carbon capture and storage,” said Huuse. 

    Now the team are busy documenting other examples of this process and assessing how exactly it impacts our understanding of subsurface reservoirs and sealing intervals.

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  • Volcano Ice Unlocks Age of Milky Ways Core Gas’

    Volcano Ice Unlocks Age of Milky Ways Core Gas’

    Researchers have found clouds of cold gas embedded deep within larger, superheated gas clouds – or Fermi bubbles – at the Milky Way’s center. The finding challenges current models of Fermi bubble formation and reveals that the bubbles are much younger than previously estimated.

    “The Fermi bubbles are enormous structures of hot gas that extend above and below the disk of the Milky Way, reaching about 25,000 light years in each direction from the galaxy’s center – spanning a total height of 50,000 light years,” says Rongmon Bordoloi, associate professor of physics at North Carolina State University and corresponding author of the research.

    “Fermi bubbles are a relatively recent discovery – they were first identified by telescopes that ‘see’ gamma rays in 2010 – there are different theories about how it happened, but we do know that it was an extremely sudden and violent event, like a volcanic eruption but on a massive scale.”

    Bordoloi and the research team used the U.S. National Science Foundation Green Bank Telescope (NSF GBT) to observe the Fermi bubbles and get high resolution data about the composition of the gas within and the speed at which it is moving. These measurements were twice as sensitive as previous radio telescope surveys of the Fermi bubbles and allowed them to observe finer detail within the bubbles.

    Most of the gas inside the Fermi bubbles is around 1 million degrees Kelvin. However, the research team also found something surprising: dense clouds of neutral hydrogen gas, each one measuring several thousand solar masses, dotted within the bubbles 12,000 light years above the center of the Milky Way.

    “These clouds of neutral hydrogen are cold, relative to the rest of the Fermi bubble,” says Andrew Fox, ESA-AURA Astronomer at the Space Telescope Science Institute and coauthor of the paper.

    “They’re around 10,000 degrees Kelvin, so cooler than their surroundings by at least a factor of 100. Finding those clouds within the Fermi bubble is like finding ice cubes in a volcano.”

    Their existence is surprising because the hot (over 1 million degrees Kelvin), high-velocity environment of the nuclear outflow should have rapidly destroyed any cooler gas.

    “Computer models of cool gas interacting with hot outflowing gas in extreme environments like the Fermi bubbles show that cool clouds should be rapidly destroyed, usually within a few million years, a timescale that aligns with independent estimates of the Fermi bubbles’ age,” Bordoloi says. “It wouldn’t be possible for the clouds to be present at all if the Fermi bubbles were 10 million years old or older.

    “What makes this discovery even more remarkable is its synergy with ultraviolet observations from the Hubble Space Telescope (HST),” Bordoloi says. “The clouds lie along a sightline previously observed with HST, which detected highly ionized multiphase gas, ranging in temperatures from a million to 100,000 Kelvin – which is what you’d expect to see if a cold gas is getting evaporated.”

    The team was also able to calculate the speed at which the gases are moving, which further confirmed the age.

    “These gases are moving around a million miles per hour, which also marks the Fermi bubbles as a recent development,” Bordoloi says. “These clouds weren’t here when dinosaurs roamed Earth. In cosmic time scales, a million years is the blink of an eye.”

    “We believe that these cold clouds were swept up from the Milky Way’s center and carried aloft by the very hot wind that formed the Fermi bubbles,” says Jay Lockman, an astronomer at the Green Bank Observatory and coauthor of the paper. “Just as you can’t see the motion of the wind on Earth unless there are clouds to track it, we can’t see the hot wind from the Milky Way but can detect radio emission from the cold clouds it carries along.”

    This discovery challenges current understanding of how cold clouds can survive the extreme energetic environment of the Galactic Center, placing strong empirical constraints on how outflows interact with their surroundings. The findings provide a crucial benchmark for simulations of galactic feedback and evolution, reshaping our view of how energy and matter cycle through galaxies.

    The work appears in Astrophysical Journal Letters and is supported by the National Science Foundation under grant number AST-2206853.

    -peake-

    /Public Release. This material from the originating organization/author(s) might be of the point-in-time nature, and edited for clarity, style and length. Mirage.News does not take institutional positions or sides, and all views, positions, and conclusions expressed herein are solely those of the author(s).View in full here.

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  • Vortex Particle Method Boosts High Reynolds Flow Simulations

    The Vortex Particle Method (VPM), a meshless vortex flow simulation approach, is gaining traction for its efficient simulation of unsteady vortex wakes evolution that is shed by aircrafts, rotors and wind turbines. It outperforms traditional grid-based CFD methods with faster computation, lower dissipation, and easier satisfaction of the CFL stability condition. However, traditional VPM has huge challenge on accurately simulating these complex flows, due to its poor numerical stability, which is compromised by factors such as Lagrangian particle distortion, vorticity field divergence, and inadequate modeling of turbulent dissipation. These issues restrict its application in high Reynolds number and high velocity gradient flows.

    Recently, a team of aviation researchers led by Min Chang from Northwestern Polytechnical University in China have developed a Stability-enhanced VPM (SEVPM) based on a Reformulated VPM (RVPM) constrained by conservation of angular momentum. SEVPM integrated a relaxation scheme to suppress the divergence of the vorticity field and coupled a Sub-Grid Scale (SGS) model to account for turbulence dissipation caused by vortex advection and vortex stretching. These advancements enable stable, high-fidelity simulations of complex flows that were previously computationally prohibitive.

    The team published their work in the Chinese Journal of Aeronautics (Vol. 38, Issue 7, 2025).

    The new SEVPM addresses these issues by incorporating a Reformulated VPM (RVPM) that enforces angular momentum conservation, a relaxation scheme to maintain a divergence-free vorticity field, and a novel Sub-Grid Scale (SGS) model that accounts for turbulence dissipation from both vortex advection and stretching. These advancements enable VPM more stable and precise simulations of complex fluid dynamics, providing engineers and researchers with a more reliable tool for predicting fluid behavior of vortex flow in practical applications.

    The researchers demonstrated that their SEVPM can accurately and stably simulate high Reynolds number flows and shear turbulence. Through a series of validation cases, including isolated vortex ring evolution, leapfrogging vortex rings, and round turbulent jet simulations, they showed that the new method significantly improves numerical stability and accurately resolves fluctuating components and Reynolds stresses in turbulence. This advancement paves the way for more reliable and efficient computational simulations in fluid dynamics, which is essential for understanding and predicting complex flow phenomena in engineering applications. “Engineers hit a wall simulating shear turbulence like jet exhausts or rotor interactions with traditional VPM. Our work tears down that wall,” says lead author Xiaoxuan Meng.

    The researchers plan to further validate and refine the Stability-enhanced VPM by applying it to more complex and realistic flow scenarios. Future work includes simulating the aerodynamic interactions of multirotor systems, wake dynamics of wind turbines, and other practical applications in aeronautics and renewable energy. The ultimate goal is to establish the Stability-enhanced VPM as a robust computational tool for high-fidelity fluid flow simulations, enabling more accurate predictions and driving innovation in design and optimization of aerospace and energy systems. “Our ultimate goal is making high-fidelity turbulence simulation as routine as structural analysis,” says Min Chang. “This unlocks smarter, greener aviation and energy systems.”

    Original Source

    Xiaoxuan Meng, Junqiang Bai, Ziyi Xu, Min Chang, Zhe Hui. Stability-enhanced viscous vortex particle method in high Reynolds number flow and shear turbulence[J]. Chinese Journal of Aeronautics, 2025, 38(7): 103361, https://doi.org/10.1016/j.cja.2024.103361 .

    About Chinese Journal of Aeronautics

    Chinese Journal of Aeronautics (CJA) is an open access, peer-reviewed international journal covering all aspects of aerospace engineering, monthly published by Elsevier. The Journal reports the scientific and technological achievements and frontiers in aeronautic engineering and astronautic engineering, in both theory and practice. CJA is indexed in SCI (IF = 5.7, Q1), EI, IAA, AJ, CSA, Scopus.

    /Public Release. This material from the originating organization/author(s) might be of the point-in-time nature, and edited for clarity, style and length. Mirage.News does not take institutional positions or sides, and all views, positions, and conclusions expressed herein are solely those of the author(s).View in full here.

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