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  • Multi-issuance stablecoins and MiCA’s first real credibility test – CEPS

    Multi-issuance stablecoins and MiCA’s first real credibility test – CEPS


    The EU’s Markets in Crypto-Assets Regulation (MiCA) is now the world’s most comprehensive regulatory framework for digital assets. This ECRI In-Depth Analysis paper dives into the ongoing regulatory controversy surrounding multi-issuance stablecoins under MiCA. While MiCA provides a comprehensive framework for crypto assets, diverging institutional interpretations have created uncertainty over whether jointly issued stablecoins across EU and non-EU entities are permitted. The European Central Bank warns of prudential and sovereignty risks, whereas the European Commission has pursued a narrow administrative approach.

    By analysing MiCA’s legal provisions, existing safeguards and recent US developments, this In-Depth Analysis paper argues that exclusion would undermine consumer protection and competitiveness. Instead, immediate Commission clarification through Q&A guidance, followed by medium-term legal refinements, are needed to safeguard MiCA’s credibility.

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  • Ancient survivors: Dragonflies now face their toughest survival test

    Ancient survivors: Dragonflies now face their toughest survival test

    Dragonflies outlasted the dinosaurs and even endured asteroid strikes. But now they face a survival threat unlike any before. Rising heat and wildfires are reshaping the very traits they depend on to attract mates.

    A study from the University of Colorado Denver shows how this shift could push some species toward local extinction. Traits that once drew partners are now putting dragonflies at risk.


    “Dragonflies have survived asteroids, but now climate change and wildfires are threatening them in ways evolution can’t keep up with,” said lead author Sarah Nalley, a PhD student in CU Denver’s Integrative Biology program.

    “Our findings suggest that adaptation alone may not be fast enough to protect species in a rapidly changing climate.”

    When ornaments backfire

    Many dragonflies have dark spots on their wings. These patterns attract mates. They also absorb heat. In hotter regions and burned habitats, that heat builds too quickly. Males tire, rest, and lose chances to compete for females.

    Thermal imaging confirmed the problem. Dark spots made wings hotter, faster. Unlike the peppered moth, where wing color affected survival through camouflage, dragonflies face a different pressure. Here, color weakens reproductive success. Survival is not enough if mating fails.

    This twist highlights a blind spot in conservation. Scientists usually check if species survive hotter, drier habitats. But if mating collapses, the population vanishes regardless of survival, leaving ecosystems weaker and biodiversity loss far greater.

    Dragonfly survival amid wildfires

    “This changes how we think about vulnerability,” said Professor Michael Moore. “It’s not just about whether animals can survive after wildfire – it’s about whether they can reproduce in those modified environments. That’s the key to long-term survival.”

    If reproduction falters, decline accelerates. And dragonflies matter. They eat mosquitoes, keeping insect numbers in check. They also feed birds, fish, and amphibians. Lose them, and entire food webs shift, unraveling in unpredictable ways.

    Dragonflies have always seemed resilient. But this study suggests they may not keep pace with today’s rapid changes, showing how climate and fire pressures can overwhelm even long-lasting species once thought secure.

    The project began as a class assignment in Professor Moore’s course. Students worked with open datasets: wildfire maps from the U.S. Geological Survey, climate records, and citizen science observations spanning 40 years. No external funding backed the research.

    Despite the simple beginnings, the analysis uncovered a serious trend. Dragonflies with ornamental wings are disappearing from fire-damaged and hotter regions. The data gave a broad view of how climate and wildfires interact with reproductive traits.

    Nalley brought personal motivation. She lost her home in Superior, Colorado, during the 2021 Marshall Fire. That experience shaped her focus.

    “I knew I wanted to study animals – and after the fire, I knew I wanted to study wildfires too,” said Nalley. “That experience pushed me to ask how animals are affected not just by surviving a fire, but by whether they can still reproduce and carry on the species afterward.”

    Lessons for conservation

    The findings stretch beyond dragonflies. If ancient predators that once ruled the skies falter, what about other species? The research shows conservationists must look past survival rates. Reproduction matters just as much.

    “Working with Sarah pushed me to think about my own research in a new way,” said Moore. “She came in with great questions about wildfires and reproduction that made me reconsider how I approach these big ecological issues.”

    The study’s message is clear: ecosystems don’t just need species to live, they need them to breed. Dragonflies warn us of what happens when natural signals of attraction turn into liabilities, threatening stability, biodiversity, and long-term ecological resilience everywhere.

    Dragonfly decline from wildfires

    Dragonflies have been here for hundreds of millions of years. Their decline would mark a profound loss. More than that, it would unsettle the balance of ecosystems that depend on them.

    The CU Denver research shows how quickly environmental pressures reach into the smallest details of life – courtship displays, wing patterns, mating chances. Those details decide whether a species thrives or disappears, shaping both present ecosystems and future biodiversity.

    Dragonflies are not just survivors from deep time. They are indicators of how even the most resilient animals can stumble in a warming, fire-prone world.

    The study is published in the journal Nature Climate Change.

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  • Contraceptive Tied to Higher Brain Tumor Risk in Women – Medscape

    1. Contraceptive Tied to Higher Brain Tumor Risk in Women  Medscape
    2. Depo-Provera Meningioma Side Effects Significantly Increased Among Women Over 31: Study  AboutLawsuits.com
    3. Prolonged use of injectable contraceptive tied to brain tumor diagnoses  Medical Xpress
    4. Brain Tumor Risk Rises With Birth Control Shot  MedPage Today

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  • Cervical cancer cases on rise in Pakistan

    Cervical cancer cases on rise in Pakistan

    Cervical cancer, one of the most preventable yet deadly diseases, is rising at an alarming rate in Pakistan, where more than 5,000 women are diagnosed and over 3,000 lose their lives each year, as health authorities and international partners now launch the country’s first HPV vaccination campaign in September 2025 to protect millions of girls against the virus.
     
    Pakistan currently has an estimated 68.6 million women aged 15 and older at risk of developing cervical cancer. The disease ranks as the third most common cancer among women in the country and the second most prevalent among women aged 15 to 44. Despite its severity, awareness remains alarmingly low, and stigma surrounding women’s reproductive health discourages many from seeking timely diagnosis and treatment.
     
    The primary cause of cervical cancer is the Human Papillomavirus (HPV). In Pakistan, about 0.5 percent of women in the general population carry HPV types 16 or 18, which account for nearly 88 percent of invasive cervical cancer cases.

    However, late detection has resulted in a staggering mortality rate of 60 to 85 percent, far higher than in many other countries. Medical experts emphasize that regular screening and HPV vaccination are the most effective ways to curb this disease, but these measures have been slow to reach communities.
     
    For years, Pakistan lacked a national strategy to address cervical cancer. Screening programs were inconsistent and largely unavailable in rural areas, where health facilities often lack trained staff and laboratory support. Social taboos around reproductive health further contributed to the underreporting of cases and delayed care. As a result, thousands of women lose their lives each year to a disease that could have been prevented.
     
    To counter this crisis, the government, with support from international health organizations, has launched Pakistan’s first nationwide HPV vaccination campaign. The campaign, beginning in Sindh in September 2025, will target around 4.1 million girls aged 9 to 14, aiming to protect exposure to the virus. Routine vaccination is scheduled to begin in January 2026, with gradual expansion to Punjab, Islamabad, Azad Kashmir, Khyber Pakhtunkhwa, Balochistan, and Gilgit-Baltistan by 2027.
     
    Alongside vaccination, nearly 49,000 health workers are being trained to spread awareness, educate families, and administer vaccines effectively in both urban and rural areas.
     
    Health experts stress that vaccination alone will not be enough. Awareness campaigns, affordable screening, and strengthened cancer registries are equally critical to reducing the national burden. In many cases, women are unaware of the availability of simple tests like PAP smears or HPV screening, while in others, facilities lack the infrastructure to conduct them. Without addressing these systemic gaps, the disease is likely to continue taking lives, particularly in underserved areas.
     
    Cervical cancer is one of the few cancers that can be prevented with vaccines and detected early through screening. In Pakistan, where cultural stigma and health inequities remain barriers, breaking the silence around women’s health is essential.
     
    Each preventable death represents not just a number, but a family torn apart. Public health advocates insist that with the right mix of education, prevention, and care, thousands of lives can be saved, but the time to act is now, before the statistics climb even higher.


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  • Alonso reveals the ‘anonymous’ drive that he ranks as his best in F1 so far

    Alonso reveals the ‘anonymous’ drive that he ranks as his best in F1 so far

    Fernando Alonso has shared the untold story behind what he believes to be his best drive in Formula 1 up to this point, picking out an “anonymous” performance at the Malaysian Grand Prix a decade-and-a-half ago.

    Alonso is the most experienced driver on the F1 grid, having made his debut back in 2001 and racked up 417 starts so far – scoring more than 2,300 points, 106 podium finishes, 32 wins, 22 pole positions and two world titles as of the 2025 Italian Grand Prix.

    However, rather than any of those successes topping his list of greatest races across that period, the 44-year-old Spaniard would go back to the early-2010s and a particularly challenging Sunday afternoon with Ferrari.

    Speaking in an interview with Maaden, a partner of his current team Aston Martin, Alonso instead made reference to the 2010 Malaysian Grand Prix, where race-long gearbox and clutch issues blighted his efforts to recover from 19th on the grid (following a shock Q1 exit amid changeable weather conditions).

    “There are many races that people were not maybe aware of,” said Alonso, reasoning why he did not choose one of his legendary wins, such as the 2012 European Grand Prix in Valencia, which saw him charge from 11th to the top step of the podium.

    “It was Malaysia, Sepang [in 2010], where I had a problem on the gearshift. The gearbox was broken, semi-broken, the clutch had a problem – the gears went up okay, but not down.

    “Around halfway through the race I tried to downshift into Turn 1 and from seventh [gear] I went to only fifth instead of second, so I did Turn 1 in fifth, I lost time, and I realised in the following corner that there was a problem.

    “Out of desperation, I tried to blip the throttle on a downshift, because if not I would retire the car in that lap. I blipped the throttle and the downshift went in, so on the next braking point I blipped the throttle four times and four downshifts [happened].

    “I communicated to the team, ‘What I’m doing is right or wrong? I will break the gearbox within one lap?’ They said, ‘Keep doing what you’re doing, the gearbox is safe by doing that’.

    “I did like 30 laps like that, so the upshift was okay, then braking I had to brake and, while having the pressure on the brake pedal, I had to blip the throttle a couple of times to do the downshifts that I wanted – obviously synchronising the throttle and the paddle shift.”

    An engine failure a couple of laps from the chequered flag left Alonso 13th in the overall classification, without a point to his name, but even today he takes great pride from the performance he was able to deliver while managing so many issues.

    “The engineers said [after the race], ‘I don’t know [how] you came [up] with that solution that fast, because that could be a solution, but you did it like in 13 or 14 seconds, the second corner after you had a problem’,” added Alonso. “I said, ‘I hate losing, I hate retiring the car, I will try everything before accepting that we have to DNF’.

    “[It was] completely anonymous, no one will remember that race, but the level of energy that I had to put [into] that race, the level of concentration, focus, and [to] instinctively come out with a solution [to] a problem that was never tested or experienced… I think it was quite a race to remember.”

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  • Top stocks to watch from analysts include Nvidia, FedEx, UPS, Amazon

    Top stocks to watch from analysts include Nvidia, FedEx, UPS, Amazon

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  • Chashma Sugar Mills Completes Amalgamation with Ultimate Whole Foods

    Chashma Sugar Mills Completes Amalgamation with Ultimate Whole Foods

    Chashma Sugar Mills Limited (CSM) has officially completed its amalgamation with its wholly-owned subsidiary, Ultimate Whole Foods (Private) Limited.

    The announcement was made in a notice submitted to the Pakistan Stock Exchange (PSX).

    The merger, previously approved under the Scheme of Amalgamation, consolidates the operations of the two entities, with Chashma Sugar Mills Limited serving as the transferee company.

    This strategic move is expected to streamline operations, enhance efficiency, and create new growth opportunities for the company.

    Chashma Sugar Mills Limited, headquartered in Islamabad, operates multiple factories in Dera Ismail Khan, including sugar mills and an ethanol fuel plant.

     


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  • Ireland threatens to withdraw from Eurovision if Israel participates

    Ireland threatens to withdraw from Eurovision if Israel participates

    The Irish state broadcaster RTÉ has said it will not take part in the 2026 Eurovision Song Contest “if the participation of Israel goes ahead”.

    In a statement, RTÉ said that Ireland’s participation in the event “would be unconscionable given the ongoing and appalling loss of lives in Gaza”.

    Ireland has won the contest seven times in total, most recently in 1996.

    RTÉ will make a final decision once the Eurovision organisers, the European Broadcasting Union, makes its decision.

    Next year’s contest will be held in May in Vienna.

    Slovenia’s national broadcaster, RTVSLO, has also said it will withdraw from the competition if Israel participates.

    Spain’s Culture Minister Ernest Urtasun has said that his country may also not take part should Israel participate.

    In a statement on Thursday, RTÉ said: “It is RTÉ’s position that Ireland will not take part in the 2026 Eurovision Song Contest, if the participation of Israel goes ahead, and the final decision regarding Ireland’s participation will be made once the EBU’s decision is made”.

    It added: “RTÉ is also deeply concerned by the targeted killing of journalists in Gaza, the denial of access to international journalists to the territory, and the plight of the remaining hostages.”

    Prior to this year’s Eurovision in May, RTÉ asked the EBU for a discussion on Israel’s inclusion in the Eurovision Song Contest.

    At that time, its director general, Kevin Bakhurst, said he was “appalled by the ongoing events in the Middle East and by the horrific impact on civilians in Gaza, and the fate of Israeli hostages”.

    He added that he was mindful of RTÉ’s obligations to maintain objectivity in covering the war in Gaza.

    “We are also very mindful of the severe political pressure on Israel’s public service broadcaster, Kan, from the Israeli government,” he said.

    Earlier this year, more than 70 former Eurovision contestants signed a letter calling on the organisers to ban Israel from the 2025 competition.

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  • Your morning coffee could secretly be weakening antibiotics

    Your morning coffee could secretly be weakening antibiotics

    Ingredients of our daily diet – including caffeine – can influence the resistance of bacteria to antibiotics. This has been shown in a new study by a team of researchers at the Universities of Tübingen and Würzburg led by Professor Ana Rita Brochado. They discovered bacteria such as Escherichia coli (E. coli) orchestrate complex regulatory cascades to react to chemical stimuli from their direct environment which can influence the effectiveness of antimicrobial drugs.

    In a systematic screening, Brochado’s team investigated how 94 different substances – including antibiotics, prescription drugs, and food ingredients – influence the expression of key gene regulators and transport proteins of the bacterium E. coli, a potential pathogen. Transport proteins function as pores and pumps in the bacterial envelope and control which substances enter or leave the cell. A finely tuned balance of these mechanisms is crucial for the survival of bacteria.

    Researchers describe phenomenon as an ‘antagonistic interaction’

    “Our data show that several substances can subtly but systematically influence gene regulation in bacteria,” says PhD student Christoph Binsfeld, first author of the study. The findings suggest even everyday substances without a direct antimicrobial effect – e.g. caffeinated drinks – can impact certain gene regulators that control transport proteins, thereby changing what enters and leaves the bacterium. “Caffeine triggers a cascade of events starting with the gene regulator Rob and culminating in the change of several transport proteins in E. coli – which in turn leads to a reduced uptake of antibiotics such as ciprofloxacin,” explains Ana Rita Brochado. This results in caffeine weakening the effect of this antibiotic. The researchers describe this phenomenon as an ‘antagonistic interaction.’

    “Caffeine triggers a cascade of events starting with the gene regulator Rob and culminating in the change of several transport proteins in E. coli – which in turn leads to a reduced uptake of antibiotics such as ciprofloxacin.” Ana Rita Brochado

    This weakening effect of certain antibiotics was not detectable in Salmonella enterica, a pathogen closely related to E. coli. This shows that even in similar bacterial species, the same environmental stimuli can lead to different reactions – possibly due to differences in transport pathways or their contribution to antibiotic uptake. President Prof. Dr. Dr. h.c. (Dōshisha) Karla Pollmann emphasizes: “Such fundamental research into the effect of substances consumed on a daily basis underscores the vital role of science in understanding and resolving real-world problems.”

    The study, which has been published in the scientific journal PLOS Biology, makes an important contribution to the understanding of what is called ‘low-level’ antibiotic resistance, which is not due to classic resistance genes, but to regulation and environmental adaptation. This could have implications for future therapeutic approaches, including what is taken during treatment and in what amount, and whether another drug or food ingredient – should be given greater consideration.

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  • European Qualifiers for the 2026 World Cup: What to look out for on Matchday 7 and 8 – UEFA.com

    1. European Qualifiers for the 2026 World Cup: What to look out for on Matchday 7 and 8  UEFA.com
    2. What teams are qualified for 2026 World Cup? Full list, latest updates  USA Today
    3. How five-star England thrashed Serbia to extend their 100 per cent World Cup qualifying record – The Athletic  The New York Times
    4. Europe’s Football Giants Battle for World Cup Glory  Devdiscourse
    5. European World Cup qualifying: Spain reigns, Tuchel’s England emerges and Mbappé keeps France steady  ehextra.com

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