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  • An upcoming phone could offer double the battery capacity of S25 Ultra

    An upcoming phone could offer double the battery capacity of S25 Ultra

    Robert Triggs / Android Authority

    TL;DR

    • HONOR is apparently working on a smartphone with a 10,000mAh battery.
    • This would be double the capacity of the Galaxy S25 Ultra’s battery and larger than some tablet batteries.
    • It’s highly likely that the phone won’t offer a 10,000mAh battery if it launches in the EU.

    We’re seeing more and more smartphones with huge batteries thanks to silicon-carbon battery tech. HONOR recently launched the HONOR Power, which packs an 8,000mAh battery. However, it looks like the company could step up with an upcoming phone.

    Leaker Digital Chat Station claimed on Weibo that HONOR has started testing a device with a 10,000mAh battery and a yet-to-be-released Dimensity 8500 processor. You can view the machine-translated screenshot of the post below.

    HONOR 10000mah phone testing Digital Chat Station

    A 10,000mAh phone would have double the battery capacity of the Galaxy S25 Ultra (5,000mAh). It would also be significantly larger than the OnePlus 13 battery (6,000mAh). In fact, this would also be larger than some Android tablets like the Pixel Tablet (7,020mAh) and Galaxy Tab S10 FE (8,000mAh). Either way, a phone with a 10,000mAh battery would likely offer at least three full days of typical usage.

    Would you buy a phone with a 10,000mAh battery?

    0 votes

    This wouldn’t be the first phone with a 10,000mAh battery, as niche brands frequently offer rugged phones with larger batteries. However, these devices tend to be incredibly thick and heavy. By contrast, the previously released HONOR Power has an 8,000mAh battery but measures 7.98mm thin and weighs 209 grams. So we hope this new phone offers a similarly slim and light design.

    There’s no word on a release timeline for this phone, but we hope to see a global release. Unfortunately, EU regulations mean that the device will likely see a huge drop in battery capacity if it comes to Europe.

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  • Late Queen ‘knew what was going on’ with Prince Andrew – author claims | Royal | News

    Late Queen ‘knew what was going on’ with Prince Andrew – author claims | Royal | News

    Queen Elizabeth allegedly knew “exactly what was going on” with Prince Andrew and “colluded” in covering it up, the author of a new bobshell book has claimed. The Duke of York has been embroiled in several scandals over the years, most of which are coming back into the spotlight as a new, explosive and unauthorised biography of him and his family is set to be released this week.

    Andrew Lownie’s Entitled: The Rise And Fall Of The House Of York has had some of its parts serialised by the Daily Mail recently, bringing shocking new claims about the York family, including their finances, the Duke’s sex life, his alleged physical altercation with Prince Harry, and the Duke’s behaviour to members of staff. Buckingham Palace has not commented on the claims yet as it does not speak for non-working members of the Royal Family; however, Prince Harry’s reps denied the claims that a physical fight between the two ever took place.

    Now, the author gave a new interview to The Sunday Times and spoke about Andrew’s dodgy finances, claiming that he would often conduct private business activities during taxpayer-funded trips when he was still a working royal.

    But he also noted on the “sheer brazenness” of the whole thing and alleged that the Palace and the Queen knew all about it.

    He told the newspaper: “This is what shocked me, the cover-up from the Palace. They knew exactly what was going on. People are not going to like it, but the Queen was colluding in this.

    “I originally thought she just put her head in the sand. But I increasingly have come to the view that she knew exactly what was going on and allowed it to happen.”

    The author added that, unlike the late monarch, who was “burdened by maternal adoration”, as per the outlet, King Charles has always seen his brother much more clearly, “As does William”.

    In a previous interview to the Daily Mail’s Palace Confidential, Mr Lownie issued a warning to King Charles about his brother.

    The author said: “I would keep the whole York family at a distance.”

    He added: “Fergie should not be invited to events and the daughters should not be made working royals. I believe there are more scandals to emerge.”

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  • GPT-5 jailbroken in under 24 hours: “shockingly low” safety – Cybernews

    1. GPT-5 jailbroken in under 24 hours: “shockingly low” safety  Cybernews
    2. Researchers Uncover GPT-5 Jailbreak and Zero-Click AI Agent Attacks Exposing Cloud and IoT Systems  The Hacker News
    3. GPT-5 surrendered to the hackers in 24 hours and gave out a “recipe” for a bomb, more likely 4o  ITC.ua
    4. Cisco Talos Researcher Reveals Method That Causes LLMs to Expose Training Data  TechRepublic

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  • Did you see the Sturgeon Moon? Now watch the Moon meet 6 different Solar System planets in the sky

    Did you see the Sturgeon Moon? Now watch the Moon meet 6 different Solar System planets in the sky

    Did you watch the Sturgeon Moon rise over the weekend of 8–9 August?

    The full Sturgeon Moon marked the beginning of the Moon’s meeting with 6 Solar System planets, which kicks off this week.

    Because the Moon tracks eastwards across the sky night after night, over the coming weeks it will encounter Saturn and Neptune, then Uranus, then Jupiter, Venus and Mercury.

    Get weekly stargazing advice by signing up to our e-newsletter and subscribing to our YouTube channel

    Nearly-full Sturgeon Moon captured through the arches of the Colosseum in Rome, Italy, by Paolo Palma, 7 August 2025. Equipment: Nikon Coolpix p510 camera, single shot

    And the Moon, having reached full Moon on 8/9 August, is now waning, meaning it’s becoming less illuminated night after night, moving back through its gibbous then crescent phases.

    The coming evenings offer a good chance to see the waning Moon meet the planets of the Solar System in the night sky.

    This will culminate in the Moon joining in the August 2025 planet parade, forming a beautiful alignment with Mercury, Venus and Jupiter.

    Having been full, the Moon is now 'waning', meaning it's going back through its gibbous and then crescent phases. Credit: Yaorusheng / Getty Images
    Having been full, the Moon is now ‘waning’, meaning it’s going back through its gibbous and then crescent phases. Credit: Yaorusheng / Getty Images

    The Moon’s Solar System tour begins

    The Moon’s meeting with the planets begins on the nights of 11–13 August, when the Moon is close to Saturn and Neptune, which are currently close to one another in the night sky.

    Saturn rises in the east around 22:30 BST (21:00 UTC) and is visible in the southeast shortly after midnight.

    Neptune is just above Saturn, but not visible with the naked eye so you’ll need binoculars or a telescope to see it.

    On the night of 11 August and past midnight on 12 August, Saturn can be seen slightly below and to the left of the Moon.

    Then on the evening of 12 August and past midnight on 13 August, the Moon is now to the left of Saturn.

    The Moon will continue to track eastwards night after night, so the evenings following 13 August are a good time to get out your telescope and see if you can spot faint Neptune just above Saturn, as the bright Moon is moving out of the way.

    Chart showing the location of Uranus near the Pleiades in August 2025. Credit: Pete Lawrence
    Chart showing the location of Uranus near the Pleiades in August 2025. Credit: Pete Lawrence

    On the evenings of 15–17 August, the Moon tracks past the beautiful blue open star cluster known as the Pleiades in the constellation Taurus.

    Uranus is currently close to the Pleides, which means the Moon is also passing Uranus, too.

    Get out your binoculars or telescope and see if you can observe the distant planet once the Moon moves out of the way.

    For more info on how to do this, read our guide to observing Uranus in August 2025.

    See Mercury, Venus, Jupiter and the Moon in a straight line in the east on the morning of 18 August 2025. Uranus is also visible, but trickier to see, while Saturn and Neptune are visible in the south. Credit: Stellarium
    See Mercury, Venus, Jupiter and the Moon in a straight line in the east on the morning of 18 August 2025. Uranus is also visible, but trickier to see, while Saturn and Neptune are visible in the south. Credit: Stellarium

    In the very early hours of 18 August, and the following morning on 19 August, if you can get a clear view of the eastern horizon before sunrise, you’ll see the Moon forming a line with Mercury, Venus and Jupiter, stretching upwards.

    Mercury will be very close to the horizon, followed by Venus, then Jupiter and the Moon at the top.

    Take care when observing the sky this close to sunrise, as looking directly at the Sun without proper solar observing equipment can damage your eyesight.

    You should only observe the planets well before the Sun begins to rise above the horizon.

    The Moon forms a triangle with Venus and Jupiter on the morning of 20 August 2025. Credit: Pete Lawrence
    The Moon forms a triangle with Venus and Jupiter on the morning of 20 August 2025. Credit: Pete Lawrence

    On 20 August, the Moon will have tracked further east, now forming a beautiful triangle with Venus and Jupiter.

    Then on 21 August, the Moon is just above Mercury in the very early hours before sunrise.

    From this point onwards, Mercury is becoming much easier to see in the morning sky, having emerged from the glare of the rising Sun.

    This makes the 21 August meeting between Mercury and the Moon a standout moment for observing Mercury.

    The Moon meets Mercury in the very early hours of 21 August. Credit: Pete Lawrence
    The Moon meets Mercury in the very early hours of 21 August. Credit: Pete Lawrence

    From 22 August onwards, the Moon is approaching its ‘new Moon’ phase, when it’s swallowed by the morning sunrise, and is no longer visible.

    That marks the end of this meeting of the Moon and planets, but as August draws to a close, we’ll notice the days becoming shorter and the nights becoming longer, meaning we’re entering into a great time for stargazing.

    If you observe the Sturgeon Moon or the Moon’s meeting with the planets this month, share your observations and images with us by emailing contactus@skyatnightmagazine.com

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  • Meteor explodes in fireball and sonic boom over Australia – MSN

    1. Meteor explodes in fireball and sonic boom over Australia  MSN
    2. Watch: Meteor burns across Australian night sky  BBC
    3. What was that loud bang?  Australian Broadcasting Corporation
    4. Meteor Shower Magic Over Victoria Tonight: What You Need to Know  Vocal
    5. What we know about the meteor that dazzled Victoria and lit up parts of Melbourne  The Age

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  • Universal Vaccine Development Using AI and Bioinformatics

    Universal Vaccine Development Using AI and Bioinformatics


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    Most vaccines are designed to provide immunity against just one pathogen. Vaccines for chicken pox (caused by varicella-zoster virus) were only developed to fight that one disease, for example.

    But in the wake of the COVID-19 pandemic, immune system researchers around the world are working to go beyond traditional single-pathogen vaccines.

    “Our pipeline is challenging that approach,” says Alba Grifoni, Ph.D., Research Assistant Professor at La Jolla Institute for Immunology (LJI).

    As they report in Cell, Grifoni and her colleagues have developed a research pipeline to fuel the development of “universal vaccines.” These vaccines would address broad viral families and mutated viral variants. If successful, this approach could lead to vaccines with the power to neutralize emerging SARS-CoV-2 variants and many other viruses with pandemic potential.

    The science of universal vaccines

    Many viruses belong to large viral families, and they share a family resemblance. The virus that causes COVID-19, called SARS-CoV-2, is a type of coronavirus (CoV is short for coronavirus). This means SARS-CoV-2 is closely related to common cold coronaviruses, as well as MERS coronavirus (MERS-CoV) and SARS coronavirus (SARS-CoV).

    All of these coronaviruses share certain “conserved” protein sequences that have stayed the same as the viruses have evolved. These closely related viruses share many of the same features and are recognized by some of the same T cells. T cells are white blood cells that can recognize and kill virus-infected cells to stop an infection from spreading.

    In previous studies, LJI researchers discovered that some cross-reactive T cells can detect these conserved sites, called epitopes, to target both SARS-CoV-2 and common cold coronaviruses.

    Grifoni’s laboratory is working to map out these conserved epitope regions. This work is critical for developing a universal coronavirus vaccine. Once the scientists know where T cells should strike, they can develop vaccines that deliver effective T cell immunity against many kinds of coronaviruses—including variants that haven’t even emerged yet.

    “It is important to induce a neutralizing antibody response,” says Grifoni. “But we’ve shown that T cells are much more stable in the context of viral variants, and that is because T cells look at all the proteins of the virus.”

    Using data science to fight COVID-19

    Researchers are aware of conserved coronavirus T cell epitopes, including some epitopes on the coronavirus “spike” protein. But it is harder to study which of these epitopes sparks the strongest T cell response, and researchers knew there were other promising epitopes hiding in experimental data.

    To find these conserved epitope regions, Grifoni and her team extracted and analyzed data from the Immune Epitope Database (IEDB), a public resource designed and led by LJI scientists. The IEDB provided data on more than 200 coronavirus epitopes uncovered by scientists in labs around the world.

    Grifoni worked closely with virologists at the J. Craig Venter Institute (JCVI) to compare the similarities between epitopes from different kinds of coronaviruses. The researchers used a combination of bioinformatic tools, including artificial intelligence (AI) approaches, to look for hidden similarities between the coronaviruses.

    Once Grifoni and her colleagues had their results, they compared how T cells recognized different coronavirus epitopes, including epitopes on the viral “spike” protein and those outside the spike protein. Uncovering this T cell activity gives researchers an important guide for how to target coronaviruses via a cross-reactive T cell response.

    “The idea is that if a new coronavirus emerges, we might not be able to protect from the infection, but we might be able to protect from hospitalization,” says Grifoni.

    Grifoni is thinking about the bigger picture. She says this coronavirus study shows the accuracy and usefulness of a new research pipeline. Researchers could use this same process to pinpoint conserved T cell epitopes across different respiratory viruses (such as paramyxoviruses, including measles and Nipah virus or enteroviruses, including A71 and D68) and even viral species causing hemorrhagic fevers (such as Lassa virus and Junin virus).

    “Our laboratory is collaborating with research groups that are interested in many different viral families,” says Grifoni. “We need to fill the knowledge gaps.”

    Reference: Pereira Neto TA, Zmasek C, Avalos L, et al. Highly conserved Betacoronavirus sequences are broadly recognized by human T cells. Cell. doi: 10.1016/j.cell.2025.07.015

    This article has been republished from the following materials. Note: material may have been edited for length and content. For further information, please contact the cited source. Our press release publishing policy can be accessed here.

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  • Evaluating tonsillectomy-related YouTube videos via a human expert review and the ChatGPT-4: a multi-method quality analysis | BMC Medical Education

    Evaluating tonsillectomy-related YouTube videos via a human expert review and the ChatGPT-4: a multi-method quality analysis | BMC Medical Education

    This study provides a comprehensive evaluation of the educational quality and medical accuracy of YouTube videos related to tonsillectomy, integrating human expert assessments with large language model (LLM)-based evaluations and transcript readability metrics. The findings highlight both the strengths and persistent challenges of using open-access digital platforms for disseminating patient education content.

    Consistent with previous research, the overall quality of the videos included in this analysis was moderate. The mean DISCERN score (56.3 ± 8.7) aligns with findings from Vasan et al. (2024), Strychowsky et al. (2013), and Ward et al. (2020), all of whom reported that the majority of tonsillectomy-related content on YouTube fails to meet high standards of medical reliability ([6, 8, 9]) These consistent findings reinforce concerns regarding YouTube’s limited role as a dependable source of surgical information for the public, despite its widespread use and accessibility.

    One of the most notable patterns in our analysis was the significantly lower quality of patient-generated content than videos produced by physicians, hospitals, or health associations. Both DISCERN and JAMA benchmark scores were significantly lower for patient videos—a trend that aligns with observations from prior studies. In particular, Selen et al. (2024) emphasized that videos produced by professional organizations consistently score higher in quality assessments [10]. While personal experience videos may provide emotional support and relatability, our findings corroborate those of Vasan et al. and Strychowsky et al., who caution that such narratives often lack critical clinical details and may deviate from evidence-based consensus practices [6, 8]. These results underscore the continued need for professional involvement in the creation of patient-facing health content.

    Our study also demonstrated a strong alignment between AI-generated evaluations and those of expert reviewers. Specifically, we found a moderate-to-strong correlation between the ChatGPT-4 accuracy scores and JAMA scores (ρ = 0.56, p < 0.001) and an even stronger correlation between the ChatGPT-4 completeness scores and DISCERN ratings (ρ = 0.72, p < 0.001). Furthermore, DISCERN scores significantly predicted ChatGPT-4 completeness ratings in a regression analysis (R² = 0.51, p < 0.001), highlighting the potential of ChatGPT-4 as a reliable tool for evaluating health information quality. While Demirci (2024) and Yüce et al. (2024) reported only moderate agreement between human raters and ChatGPT-4 models, citing issues such as low reproducibility and overestimation, our stronger correlations may reflect methodological enhancements, including manual transcript correction and the use of structured, task-specific prompts [11, 12]. On the other hand, our results align with those of Bal et al. (2024), who reported high concordance between ChatGPT-4 and expert classifications of language learning video content [13]. Taken together, these findings suggest that while ChatGPT-4 holds considerable promise in content evaluation, its performance may vary depending on the medical context and task.

    In terms of linguistic accessibility, the average Flesch–Kincaid Grade Level (FKGL) of the video transcripts was 8.38, which is well above the recommended sixth-grade reading level for patient education materials. This aligns with prior reports indicating that even trusted sources such as MedlinePlus often exceed ideal readability thresholds [14]. Although readability metrics were not significantly correlated with DISCERN or JAMA scores, this finding raises concerns about the accessibility of video content for individuals with lower health literacy. Given that many viewers seeking tonsillectomy-related content may include parents of pediatric patients or individuals unfamiliar with medical terminology, an eighth-grade readability level may hinder comprehension and limit the practical usefulness of the information. Enhancing the clarity and simplicity of language used in video narration or captions could improve user understanding and engagement, especially in vulnerable populations. Future educational content should aim to align more closely with the recommended sixth-grade reading level to ensure broader accessibility.

    This is one of the first studies to apply a multi-method framework combining human, AI, and readability analyses to assess the quality of tonsillectomy-related YouTube videos. Our inclusion of the ChatGPT-4 as an evaluative tool offers valuable insights into the evolving role of artificial intelligence in quality assurance for online health information. The strong correlations observed between human and AI ratings suggest that LLMs may serve as supportive prescreening tools for clinicians, educators, and platform moderators aiming to identify high-quality educational content at scale.

    Practical significance and educational implications

    While only ChatGPT-4 accuracy showed a statistically significant difference between transcript-heavy and visually-rich videos (Cohen’s d = 0.600, p = 0.030), this represents a large effect size with potential educational relevance. The 8% increase in AI-rated accuracy for visually enriched content highlights its value in enhancing comprehension—particularly for procedures like tonsillectomy that rely heavily on visual demonstration. This aligns with Mayer’s Cognitive Theory of Multimedia Learning, which posits that individuals learn more effectively when information is presented using both verbal and visual modalities [15]. Prior work in health communication also emphasizes the role of visual aids in improving understanding, recall, and engagement, especially among audiences with lower health literacy [16]. Given the consistently large effect sizes observed in correlations between AI-generated and expert ratings (ρ = 0.56–0.72), these findings support the use of LLM-based scoring tools for preliminary quality screening, provided their limitations are acknowledged.

    However, it is important to note that ChatGPT-4 only assessed the textual transcripts, and the model had no access to the actual visual or auditory elements. Therefore, the observed accuracy gains in visually rich videos may reflect indirect improvements in transcript clarity or contextual grounding, rather than a direct effect of visual features. This suggests that visual enhancements may improve the way speakers articulate or structure information, which in turn benefits AI interpretation. Future studies using AI models capable of analyzing multimodal content are needed to verify this effect directly.

    Limitations

    Several limitations should be acknowledged. First, our analysis was restricted to English-language videos, which limits the generalizability of the findings to non-English-speaking audiences. Second, despite excellent inter-rater reliability, the subjective nature of human assessments cannot be eliminated. Third, as a cross-sectional study, our findings reflect a snapshot of the YouTube landscape between May and June 2025. Another limitation of this study is the inclusion of only English-language videos. This introduces selection bias and restricts the generalizability of the findings to English-speaking populations. Language and cultural context may significantly influence both the production and the perception of health education content, as communication styles, health beliefs, and literacy expectations can vary widely across regions. Future studies incorporating multilingual datasets and cross-cultural comparisons would be valuable to understand how video quality and accessibility differ across global audiences. Given the dynamic nature of online content and search algorithms, the results may vary over time. Additionally, ChatGPT-4 evaluated only transcripts; it cannot assess visual or auditory elements, which may influence the educational quality of a video. Previous work by Yüce et al. has also noted the model’s tendency to underperform when analyzing lengthy or complex video content and highlighted that video length itself may positively correlate with quality, an aspect not addressed in this study [12].

    Future directions

    Future research should explore strategies for producing engaging and medically accurate health videos that are both accessible and algorithmically visible. Studies evaluating the optimal design features—such as visuals, narration style, and interactivity—may help enhance the visibility, reach, and impact of such content. Continued development and fine-tuning of large language models (LLMs) for healthcare-specific evaluation tasks could further strengthen their reliability and utility. Additionally, future studies incorporating patient-reported feedback through surveys may provide valuable insights into the perceived usefulness and trustworthiness of online health content, thereby bridging the gap between objective quality metrics and real-world user experience. Longitudinal analyses are also warranted to monitor how the quality of medical videos evolves in response to platform changes and shifting public expectations.

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  • PIA launches new Riyadh–Sialkot flight service

    PIA launches new Riyadh–Sialkot flight service

    Pakistan International Airlines (PIA) has inaugurated a new flight route from Riyadh, the capital of Saudi Arabia, to Sialkot.

    According to PIA officials, nearly 200,000 passengers travel annually from Riyadh to various cities in Pakistan.

    The new service has been introduced to cater to their convenience, offering direct travel facilities.

    PIA stated that these flights will not only provide passengers with greater ease but also further strengthen air connectivity between Pakistan and Saudi Arabia.

    Read more: PIA announces special flights to Iraq for Arbaeen pilgrims

    Earlier, Pakistan International Airlines (PIA) announced special flight operation to facilitate Arbaeen pilgrims travelling to the holy city of Najaf in Iraq, following the government’s ban on road travel to Iran and Iraq.

    According to a spokesperson for the national flag carrier, the special flights begin operating from August 8 and continue till August 11 (today).

    Return flights from Najaf to Pakistan are scheduled between August 18 and August 23.

    PIA has introduced special discounted fares, setting the ticket price at $675 for the Arbaeen flight operation.


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  • Israel assassinates 5 Al Jazeera staff: Scenes of carnage in Gaza City | Israel-Palestine conflict News

    Israel assassinates 5 Al Jazeera staff: Scenes of carnage in Gaza City | Israel-Palestine conflict News

    Israel has assassinated Al Jazeera correspondent Anas al-Sharif and four other staff in a targeted attack on a tent in Gaza City, taking the total number of journalists killed since October 7, 2023 to 269.

    Correspondent Mohammed Qreiqeh, cameramen Ibrahim Zaher and Moamen Aliwa, and their assistant Mohammed Noufal were meeting in a media tent outside al-Shifa Hospital when they were targeted by a drone.

    Two others were killed in the Sunday evening attack that has drawn condemnation.

    Al Jazeera Media Network has condemned what it called a “targeted assassination” and called it “yet another blatant and premeditated attack on press freedom”.

    “This attack comes amid the catastrophic consequences of the ongoing Israeli assault on Gaza, which has seen the relentless slaughter of civilians, forced starvation, and the obliteration of entire communities,” the network said in a statement.

    “The order to assassinate Anas Al Sharif, one of Gaza’s bravest journalists, and his colleagues, is a desperate attempt to silence the voices exposing the impending seizure and occupation of Gaza.”

    The Committee to Protect Journalists (CPJ) says it is “appalled” by Israel’s killing of Al Jazeera journalists.

    “Israel’s pattern of labeling journalists as militants without providing credible evidence raises serious questions about its intent and respect for press freedom,” said the CPJ’s regional director, Sara Qudah.

    “Journalists are civilians and must never be targeted. Those responsible for these killings must be held accountable,” Qudah added.

    Last month the CPJ said it was gravely concerned for the safety of al-Sharif as he was being “targeted by an Israeli military smear campaign”.

    Since Israel launched its war on the enclave in October 2023, it has routinely accused Palestinian journalists in Gaza of being Hamas members, as part of what rights groups say is an effort to discredit their reporting of Israeli abuses.

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  • GSK climbs after winning FDA priority review for oral gonorrhoea antibiotic

    GSK climbs after winning FDA priority review for oral gonorrhoea antibiotic

    Investing.com — GSK (NYSE:GSK) (LON:GSK) said on Monday that the U.S. Food and Drug Administration has accepted its priority review application for gepotidacin, an oral antibiotic aimed at treating sexually transmitted uncomplicated gonorrhoea.

    The drugmaker’s shares climbed 1% in London on the news.

    The company is looking to new infectious disease products, including its recently launched respiratory syncytial virus vaccine, to offset expected revenue declines from top-selling medicines and looming patent expirations in its HIV portfolio.

    Gepotidacin is already approved in the U.S. under the brand name Blujepa for treating a common urinary tract infection in women and adolescent girls.

    The FDA is expected to decide in December on its use for uncomplicated urogenital gonorrhoea, which could offer patients an oral alternative to existing injectable treatments.

    Separately, GSK and Germany’s CureVac last week resolved a long-running patent dispute with Pfizer (NYSE:PFE) and BioNTech (NASDAQ:BNTX) over mRNA vaccine technology used during the COVID-19 pandemic.

    The settlement follows BioNTech’s June agreement to acquire CureVac in an all-stock deal worth $1.25 billion to advance work on mRNA-based cancer therapies.

    Under the settlement, CureVac and GSK will receive $740 million and single-digit percentage royalties on future U.S. sales of COVID-19 vaccines, CureVac said. GSK’s share amounts to $370 million, including $50 million to adjust terms from a 2024 licence agreement that expanded their pandemic-era partnership.

    If BioNTech’s takeover of CureVac is completed, related mRNA litigation outside the U.S. will also be resolved, with GSK receiving an additional $130 million and royalties extended to non-U.S. sales. CureVac said the acquisition remains on track under the agreed terms.

    GSK said it still has separate patent cases against Pfizer and BioNTech in the U.S. and Europe, which are unaffected by this settlement.

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