Blog

  • Poverty & extremism – Newspaper

    Poverty & extremism – Newspaper

    “As long as poverty, injustice and gross inequality persist in our world, none of us can truly rest.” — Nelson Mandela

    POVERTY is frequently cited as a cause of growing extremism, but proving it is not as easy as portrayed. While Pakistan’s ranking on the Human Development Index (HDI) and poverty index confirms that poverty is a contributing factor, internal strife and socioeconomic polarisation are also significant drivers. Poor states often attribute extremism to poverty and religious misinterpretation, but by focusing solely on these two factors, they may be avoiding the need to address the demand for fair distribution of resources, as well as ethnic, sectarian, so­­ciocultural, economic and political issues.

    According to the IMF’s World Economic Outlook 2024, Burkina Faso is ranked 16th among the world’s poorest countries and ranks first on the Global Terrorism Index. Pakistan is the 50th poorest country and ranks second on the GTI. Syria and Afghanistan rank high but have unstable political conditions, making economic assessment difficult. Mali (15th poorest) ranks fourth on the GTI; Niger (sixth poorest) is fifth; Nigeria (46th poorest) is sixth; Somalia (11th poorest) is seventh. Israel, ranked 157th among poor countries, is eighth on the GTI, while Cameroon (40th poorest) ranks 10th. These rankings show a mixed picture. In some cases, there is a direct link between poverty and extremism, while in others — such as Israel — it is historical and expansionist designs that drive extremism.

    The 2025 Human Development Index underlines this link. Burkina Faso ranks 186th out of 193 countries and is first in the GTI. Pakistan is 168th in HDI, and second in GTI. Syria is 162nd and third, Mali is 188th and fourth, Niger is 187th and fifth, Nigeria is 164th and sixth, and Somalia is 192nd and seventh. Israel, by contrast, ranks 27th in HDI and eighth in GTI, Afghanistan ranks 181st and ninth, while Cameroon is 155th and 10th. This suggests that, with the exception of Israel, the top 10 GTI countries fall between 155 and 192 in HDI rankings, which indicates a strong correlation between low development and terrorism.

    Poverty is not the only factor behind violence.

    Adult literacy rankings show a similar trend. Except for Israel (86th), the top GTI-listed countries fall between 110 and 162 on adult literacy indices. This demonstrates the need to increase allocations in education.

    In practice, militant groups exploit poverty for recruitment, offering money, food, or a sense of purpose. When poverty is compounded by poor governance and ideological appeals, such areas become fertile for extremism. States must ensure school education and skill development to attract young talent instead of leaving them vulnerable and unskilled.

    According to the World Bank’s global poverty threshold of $4.20 per person per day, around 44.7 per cent of Pakistan’s population now lives below the poverty line. The Bank defines poverty as the inability to meet minimum living standards. Besides ideological reasons, poverty directly or indirectly fuels crime, violence and terrorism. Recruitment patterns of militant groups in Africa and parts of Asia confirm that poverty is a prime driver, especially when people are told their natural resources are being plundered by the elite. This sense of grievance can lead to violent resentment.

    Unemployment, coupled with poverty and emotional manipulation, plays into the hands of extremist organisations. Yet, these groups don’t only attract the uneducated. Many also require educated talent well-versed in technology. A study by Charles Russell and Bowman Miller of over 350 militants from Latin Ame­ri­­ca, Europe, Asia and the Middle East (1966 to 1970) found that two-thirds were graduates. If poverty alone caused terrorism, billions would have turned to violence, yet the reality is otherwise.

    Indeed, some of the poorest countries — Sudan, Burundi, Cen­tral African Republic, Congo and Mozam­bique — are not in the top 10 in the GTI. Ideology, identity crises, authoritarianism, lack of political freedom and human rights abuses, foreign occupation, drone strikes, online radicalisation, and perceived historical injustices also fuel extremism.

    Efforts to reduce poverty and improve education, healthcare, and governance, youth employment programmes, community engagement, transparency, accountability and public services can reduce the appeal of extremist groups. Promotion of literacy and civic education can be instrumental in the prevention of extremism as it will enable individuals to critically assess extremist narratives and explore economic opportunities. Community-based literacy programmes may also include and promote human rights, tolerance, and conflict resolution, enabling individuals to challenge extremist ideologies through dialogue.

    The writer is author of Pakistan: In Between Extremism and Peace.

    X: @alibabakhel

    Published in Dawn, July 12th, 2025

    Continue Reading

  • Intestinal microbiome and metabolite profiles linked to chemotherapy response in breast cancer

    Intestinal microbiome and metabolite profiles linked to chemotherapy response in breast cancer

    Announcing a new article publication for BIO Integration journal. Imbalances in the intestinal microbiome are closely associated with the occurrence and development of cancer, and can affect tumorigenesis by influencing the inflammatory response, regulating the immune system, producing specific metabolites, and participating in tumor signaling pathways.

    This study investigated the relationships among intestinal microbial dynamics, metabolite profiles, and neoadjuvant chemotherapy (NAC) outcomes in patients with breast cancer. Patients were stratified by Miller-Payne (MP) grade into good (MP 4-5) or poor (MP 1-3) responders. Fecal samples from patients (pre- and post-NAC) were analyzed via 16S rRNA sequencing and untargeted metabolic analysis.

    After neoadjuvant chemotherapy, the species diversity and abundance of the intestinal microbiome significantly decreased, and these trends were not correlated with neoadjuvant chemotherapy efficacy. Fusobacterium abundance remained significantly higher in poor responders than good responders post-NAC, thus suggesting its association with chemoresistance.

    The Firmicutes/Bacteroidetes ratio was lower in patients with breast cancer than healthy controls, and was correlated with the therapeutic response: this ratio rose post-NAC but remained suboptimal in poor responders. Untargeted metabolomics identified upregulated amino acids (Thr-Thr and histidine) in poor responders and elevated lipids (C17-sphinganine) in good responders. ROC (receiver operating characteristic curve) analysis validated these metabolites (AUC >0.7) as predictive biomarkers. KEGG (Kyoto Encyclopedia of Genes and Genomes) pathway analysis highlighted enrichment in mTOR signaling, endocrine resistance, and estrogen signaling pathways.

    These findings underscore the intestinal microbiome’s potential as a predictor of NAC efficacy and a therapeutic target. Modulating Fusobacterium or metabolite pathways may enhance chemotherapy response.

    Source:

    Journal reference:

    Fu, J., et al. (2025). Effects of the Intestinal Microbiome and Metabolites on Neoadjuvant Chemotherapy Efficacy in Breast Cancer. BIO Integration. doi.org/10.15212/bioi-2025-0040

    Continue Reading

  • The 10-year-old song that keeps getting bigger

    The 10-year-old song that keeps getting bigger

    Ian Youngs

    Culture reporter

    Getty Images Lord Huron singer Ben Schneider on stage in a white suit with mouth open and eyes closed mid song, with one hand on a guitar neck and the other in the air. At the 2022 Bonnaroo Music & Arts festival in Tennessee.Getty Images

    Lord Huron, led by Ben Schneider, are about to release their fifth album

    The final song on LA band Lord Huron’s second album flew well under the mainstream radar when it was released in 2015. A decade on, it’s one of the most unlikely success stories in music.

    Beyoncé and Dua Lipa may be two of the world’s top pop stars, and both put out new albums last year, but their biggest songs of 2024 did not match the popularity of a 10-year-old track by Lord Huron, according to the official Billboard global end-of-year singles chart.

    And Charli XCX may have ruled Brat summer, but her biggest hit still wasn’t as big as The Night We Met by Lord Huron in the UK last year.

    (The Night We Met was 35th on Billboard’s global chart for 2024, above Dua’s Houdini at 37 and Beyoncé’s Texas Hold ‘Em at 41; and it was 60th on the UK Official Chart Company’s end-of-year rundown, while Charli’s Guess was her biggest hit single at 73.)

    Meanwhile, the Lord Huron song is in the exclusive club of tracks that have racked up three billion Spotify plays – a club even Taylor Swift isn’t in yet.

    Videos featuring The Night We Met have had another three billion views on TikTok, according to music data tracker Chartmetric.

    “It’s unbelievable,” says Lord Huron frontman Ben Schneider of the popularity of his song, which has snowballed in recent years and shows no signs of slowing down.

    Allow Google YouTube content?

    This article contains content provided by Google YouTube. We ask for your permission before anything is loaded, as they may be using cookies and other technologies. You may want to read  and  before accepting. To view this content choose ‘accept and continue’.

    It’s not unusual for old songs to become perennial favourites on streaming and social media (see The Killers, Fleetwood Mac and Tom Odell).

    What is much rarer is for it to happen to a track that was not a hit the first time around. And The Night We Met was nowhere near.

    The aching ballad closed Lord Huron’s second LP of indie folk, Strange Trails, which was well received by the group’s loyal fanbase and critics, but only grazed the US album chart.

    The song was written as “a wistful reflection of a relationship, maybe with a sense of regret of where it’s ended up and where it started”, Schneider explains.

    “I remember writing that song and feeling like it was a very concise way to end a record. And I remember my wife saying she thought there was something really special to it. But years went by and it wasn’t like it was a hit or anything.

    “And then things just started to happen with it.”

    Getty Images Ben Schneider singing into a payphone handset as a prop on stage, also holding a guitarGetty Images

    The Night We Met had almost a billion streams on Spotify in 2024 alone

    The first thing to happen was for it to be used on the soundtrack of Netflix teen drama 13 Reasons Why in 2017.

    At first, Schneider was unsure whether to let it be on the soundtrack, but his wife told him: “Just do it, put it in the show.”

    The couple were away in France at the time. “We were gone for a few months, and when we came back my manager was like, ‘Something’s happening with this song’,” the singer recalls.

    “I figured it’d be a quick spike and then fade away, but it’s had this weird and pretty unheard of long tail, where rather than falling off into nothing, it fell off and then slowly ramped back up. And it just seems to keep going.”

    Schneider recorded a duet version with Phoebe Bridgers for another 13 Reasons Why scene in 2018. Most of its subsequent lease of life has come from its popularity on TikTok.

    It has since defied musical gravity by becoming more popular every year. In 2024, it had almost a billion streams on Spotify – 57% more than the previous year, according to Chartmetric.

    The song’s lyrics hark back to the start of a soured relationship: “I had all and then most of you / Some and now none of you / Take me back to the night we met.”

    The song has been used in various TikTok memes, and Cosmopolitan put it top of its playlist of Sad Songs to Blast When You’re Feeling Hella Moody. But it can fit a range of emotions and situations – Molly-Mae Hague used it to soundtrack her pregnancy announcement video in 2022.

    “I think everyone can relate to that sort of story and can insert their own biography into it,” Schneider reflects. “It’s a vessel that fits a lot of people’s personal stories. That’s maybe why it’s had such a lasting and slow-burning effect on people.”

    The singer says The Night We Met’s success came at a good moment in the band’s career, “because we had already established ourselves in a lot of ways”.

    “We already had a very devoted fanbase, so we weren’t necessarily locked into a one-hit-wonder status by that song.

    “Even though it far outstrips our other songs in terms of streaming and everything, we have enough going on otherwise to not feel like we’re known only for that one singular moment, which is great.”

    Cole Silberman Four band members standing in semi-darkness around an old-fashioned lit-up jukebox with "The Cosmic Selector" written in decorative lettering on the topCole Silberman

    The band’s new album, The Cosmic Selector, is named after a jukebox that transports people to parallel universes

    There is indeed a lot more to the band than one song.

    Lord Huron began as a solo project in 2010, before Schneider assembled a full line-up.

    They have released four albums of yearning, soulful and haunting Americana – with a fifth coming out on Friday.

    Their albums show Schneider’s skill as a storyteller as well as a songwriter, often containing a running thread of a storyline.

    Magic jukebox

    The new LP is titled The Cosmic Selector Vol 1 – about a 1950s-style jukebox that can transport people to alternate universes, where life has turned out differently after small decisions in the past set them on different paths.

    “I guess the past few years, as I’ve been getting a bit older, I’ve just been thinking about all the ways my own life could have gone, or could still go, or might have been,” Schneider explains.

    “Not with any sense of regret, but more with a sense of wonder at the sheer randomness of it all, and how different things could have been if very little things had gone another way.

    “So I started thinking about a collection of songs representing that randomness – the lottery that one’s lot in life is.”

    Getty Images Ben Schneider in a brown suit and hat holding a guitar and singing into a microphone on stageGetty Images

    But the controls of this magic jukebox are “busted”, he says.

    “Everything’s mislabelled. What you think you’re selecting might send you a completely different way, and everything’s on the menu – sorrow, joy, horror, love – all the ways a life can go.”

    So various characters, including one voiced by actress Kristen Stewart, are put through this dimension-hopping, life-scrambling retro randomiser. Some are based on Schneider himself, others are just made up, he says.

    Everyone has their own sliding doors moments when life could have turned out differently. For Schneider, there was the time a jazz combo played in an assembly at grade school.

    “I remember watching the bass player and being like, ‘I could be in a band some day’, and a lightbulb turned on in my head,” he says. “I think there’s a myriad of moments like that where I could have chosen one thing and didn’t, so it’s fascinating to consider that.”

    The moment in France when his wife persuaded him to allow The Night We Met to be used in 13 Reasons Why was another turning point.

    Schneider hit the jackpot in the lottery of life with that sleeper hit. He now hopes its popularity turns people on to the rest of their music.

    “I want to keep trying to move forward and making new stuff,” he says. “And hopefully something that we make will have the same kind of impact that song has had.

    “And I think over time, stuff we have already made will, I hope.”


    Continue Reading

  • Pharmacist’s Support in the Transition From Hospital to Home Care in Patients With Multiple Medications: Avoidance of Fragmentation of Care

    Pharmacist’s Support in the Transition From Hospital to Home Care in Patients With Multiple Medications: Avoidance of Fragmentation of Care


    Continue Reading

  • Monoclonal antibody delivered through the nose blocks hay fever in mice

    Monoclonal antibody delivered through the nose blocks hay fever in mice

    Approximately 40% of the European population are allergic to pollen, and their symptoms cause an estimated loss of 100 million school- and workdays every year. The prevalence of hay fever has been surging for decades and this is likely to continue– a change so fast that genetic and health changes can’t be solely responsible. Improved hygiene, the widespread use of antibiotics and antiseptics, lifestyle changes, diet, pollution, and the climate crisis are also thought to play a major role in this increase.

    But now there is new hope for sufferers. As proof-of-principle, researchers have engineered an antibody from mice, which when applied to the inside of the nose stops mice from developing hay fever and asthma symptoms in response to mugwort pollen. Mugwort is the most common cause of pollen allergies in central Asia and parts of Europe, where between 10% and 15% of people with hay fever are allergic to it.

    This is the first time a monoclonal antibody designed to block a specific pollen allergen has been delivered directly into the nose, and been shown to protect against allergy symptoms in the upper and lower airways.”


    Prof Kaissar Tabynov, director of the International Center for Vaccinology at the Kazakh National Agrarian Research University (KazNARU) in Almaty, and study’s senior author

    “In the future, similar antibodies could be developed for other major pollen allergens, such as ragweed or grass. This opens the door to a new generation of precision allergy treatments that are fast-acting, needle-free, and tailored to individual allergen sensitivities.”

    ‘Molecular shield’

    Traditional treatment is allergen-specific immunotherapy: patients are exposed to gradually increasing doses of the allergen, until they become desensitized. However, this doesn’t work for all patients, and in recent decades, so-called ‘allergen-specific monoclonal antibody therapy’ has increasingly come to the fore as an alternative.

    In allergen-specific monoclonal antibody therapy, researchers engineer antibodies of the IgG class, which either specifically recognize the allergen itself and block it, or bind to IgE antibodies in general. In either case, this prevents the allergen from triggering an allergic reaction. A disadvantage is that typically, these antibodies needed to be injected into the bloodstream – until now.

    “Our method acts immediately and locally at the lining of the nose, by neutralizing the allergen on contact. This ‘molecular shield’ not only prevents IgE antibodies from being activated, but may also reduce inflammation through other mechanisms, such as calming immune cell responses and promoting regulatory pathways,” explained Tabynov.

    The researchers injected mice with a dose of mugwort pollen, stimulating them to produce antibodies against it. The mice were then humanely euthanized and their spleens harvested to isolate white blood cells. The use of mice was approved by the local Institutional Animal Care and Use Committee, under the Ministry of Health of the Republic of Kazakhstan.

    The white blood cells were then fused with laboratory-grown cancer cells from mice with multiple myeloma. This yielded five immortal ‘hybridoma’ cell lines which each secreted a single type (hence ‘monoclonal’) of antibody against mugwort pollen. A suite of diagnostic tests showed that the most powerful was produced by hybridoma cell line XA19, which was selected for further development.

    Reduction in allergy symptoms

    To test their efficacy, purified antibodies from XA19 were administered to the interior of the nose of five mice, which had been stimulated to become allergic to mugwort pollen through injections of pollen extract. Five additional mice served as positive control: they had been similarly sensitized but received a placebo. A further five mice were the negative control, neither sensitized to the pollen nor given monoclonal antibodies. Three weeks later, all mice were exposed three times under anesthesia to an aerosol of mugwort pollen, as well as to pollen extract delivered directly inside the nose.

    The results showed that the sensitized mice given the XA19 antibody displayed a major reduction in allergy symptoms compared to controls: for example, they showed a weaker ear swelling response to the pollen (a common allergic reaction in rodents); they rubbed their nose less frequently, indicating less irritation of the upper airways; their full lung capacity was preserved upon exposure to the pollen; and they showed less inflammation inside the nostrils. Inside the lungs, levels of two inflammation-promoting molecules called cytokines were likewise reduced.

    The researchers concluded that the monoclonal antibody from XA19 is effective in blocking allergic reactions against mugwort pollen triggered by IgE, at least in mice.

    “Before this treatment can be tested in people, we need to adapt the antibody to make it suitable for humans – a process called ‘humanization’ – and conduct additional preclinical safety and efficacy studies,” said Tabynov.

    “If these are successful and provided we have adequate support, we could begin clinical trials in two to three years, though bringing it to market would likely take five to seven years. We are already planning for this transition and working on scaling up production.”

    Source:

    Journal reference:

    Tabynov, K., et al. (2025). Intranasal monoclonal antibodies to mugwort pollen reduce allergic inflammation in a mouse model of allergic rhinitis and asthma. Frontiers in Immunology. doi.org/10.3389/fimmu.2025.1595659.

    Continue Reading

  • Toxic metals in breast milk linked to infant growth problems in Guatemala

    Toxic metals in breast milk linked to infant growth problems in Guatemala

    Research led by the University of Arizona Health Sciences found a potential link between growth problems among infants and high levels of toxic metals and other elements in the breast milk of Mayan women in Guatemala’s Lake Atitlán watershed region. The findings were reported in the journal Environmental Pollution

    Guatemala has the highest rate of impaired growth, or stunting, in the Western Hemisphere. Stunting is frequently attributed to poor nutrition and infections. Many studies have linked high levels of metals in drinking water to developmental, neurological, and learning problems in young children, but this is the first study to demonstrate an association with stunting in the Americas. The new research results could contribute to a better understanding of the health impacts of such exposures and lead to new approaches for prevention in Guatemala and other countries around the world.

    Detecting toxic metals in breast milk among rural Guatemalan mothers is deeply concerning and highlights the potential role of environmental pollution in undermining child development. Our work calls for interventions to protect maternal and child health and understand how environmental concentrations of metals may be contributing to stunting and other health issues.”


    Sandra Rodríguez Quintana, MD, MPH, postdoctoral research associate in the U of A Mel and Enid Zuckerman College of Public Health

    Rodríguez Quintana has been working with communities in the Lake Atitlán watershed since 2022. Rodríguez Quintana and senior author Frank von Hippel, PhD, a professor of public health and director of the One Health program, wanted to look beyond malnutrition and poor health to ask about possible influences of environmental contaminants on children’s growth. 

    The research team studied 80 mothers and their infants from four different Lake Atitlán communities: San Juan La Laguna, San Pedro La Laguna, Panajachel and Santiago Atitlán. The scientists analyzed breast milk samples from the mothers and measured the infants’ lengths. 

    They detected concentrations of arsenic and lead that exceeded World Health Organization safety standards in breast milk in mothers from Panajachel and Santiago Atitlán. 

    Additionally, they found that higher breast milk concentrations of arsenic, barium, beryllium and lead were associated with impaired growth of infants in these communities.

    Breast milk is the best source of nutrition for infants under six months of age. It also can be a potential route of exposure to toxic metals and other contaminants that may impair neurological development and immune function. 

    The researchers also examined the levels of toxic metals and metalloids in drinking water samples in each area. 

    They found higher concentrations of arsenic and barium in Panajachel and Santiago Atitlán than in other areas, indicating that drinking water may be an important source of exposure to toxic elements. 

    “We are working with colleagues in Guatemala to develop interventions that protect maternal and child health,” von Hippel said. “Drinking water contaminated with toxic elements such as arsenic and pathogenic microbes imposes a serious burden on public health, especially for the developing child.”

    Additional U of A co-authors include Paloma Beamer, PhD, a professor of public health, associate dean of community engagement and member of the BIO5 Institute; Dean Billheimer, PhD, a professor of public health and director of statistical consulting; Sam Sneed, MPH, senior coordinator of clinical research; and BIO5 Institute statistician Maria Sans-Fuentes, PhD.

    The work was supported in part by the National Institute of Environmental Health Sciences, a division of the National Institutes of Health, under award no. P30ES006694.

    Source:

    University of Arizona Health Sciences

    Journal reference:

    Rodríguez Quintana, S., et al. (2025). Exposure to toxic metal(loid)s via breastmilk and stunting in infants living in the Lake Atitlán watershed, Guatemala. Environmental Pollution. doi.org/10.1016/j.envpol.2025.126273.

    Continue Reading

  • South Korea sees world’s lowest birth rate

    South Korea sees world’s lowest birth rate

    SEOUL  –  When she started in vitro fertilisation (IVF) last November, Kim Mi-ae knew it would be a gruelling test of patience – something she had already endured when she conceived her first child three years ago. But what shocked her this time around were the “crazy” waits at the fertility clinic. “When I went in January, it felt like everyone had made a New Year’s resolution to have a baby! Even with a reservation, I waited over three hours,” says the 36-year-old Seoul resident.

    While South Korea continues to struggle with the world’s lowest birth rates, fertility clinics are in growing demand – a bright spot in the country’s demographic crisis.

    Between 2018 and 2022, the number of fertility treatments carried out in the country rose nearly 50% to 200,000. Last year, one in six babies in Seoul were born with the help of fertility treatment. Underpinning the boom, experts say, is a shift in attitudes about family planning.

    “We have a young generation… that is used to being in control of its life,” says Sarah Harper CBE, professor in Gerontology at the University of Oxford. That control, she adds, may come in the form of single women freezing their eggs or couples trying IVF when they can’t conceive. “Whereas in previous generations there was a greater acceptance that whether you conceive or not can be a bit haphazard, now we have Korean women saying, ‘I want to plan my life.’”

    This is good news for South Korea’s government, which is trying to lift the country out of a demographic crisis. One in five people in South Korea are now aged 65 or above. As a proportion of the country’s total population, there have never been fewer babies.

    The country has repeatedly broken its own record for having the world’s lowest birth rate: 0.98 babies per woman in 2018, 0.84 in 2020 and 0.72 in 2023. If this trend continues, experts warn the population of 50 million could halve in 60 years.

    But recently there is reason for cautious optimism: instead of another record low, South Korea’s birth rate rose slightly to 0.75 in 2024 – its first increase in nine years. “It’s a small bump, but still a meaningful one,” says Seulki Choi, a professor at the Korea Development Institute’s School of Public Policy and Management. It is too early to tell whether this is the start of a much-needed reversal or just a blip. The country’s birth rate remains far below the global average of 2.2. But many like Dr Choi are cautiously optimistic. “If this trend holds, it could signal a longer-term shift,” says Dr Choi. “We need to watch how young people’s attitudes toward marriage and parenthood are changing.”

    For years, having children was the last thing on Park Soo-in’s mind. She was mostly busy at work, often only clocking off from her advertising job at 04:00.

    “I was in a company with endless overtime, so it wasn’t even something I could realistically consider,” says the 35-year-old. Things started to change after she got married two years ago. She landed a new job with better hours – and friends around her started having babies.

    “Seeing and interacting with their kids made it feel less overwhelming,” she said. “And watching my husband take initiative, doing research on pregnancy and childbirth and showing real effort, gave me confidence that we could do this.” When Ms Park and her husband had trouble conceiving, they looked to fertility treatments. Many others are doing the same, fuelling projections that the burgeoning industry could be worth more than $2bn by 2030. “This is actually an important signal for policymakers that there are still some women who want to start families but are facing … barriers to doing so,” says Jennifer Sciubba, president and CEO of the non-profit Population Reference Bureau in Washington, DC. “More than anything, this is a sign that people are unable to fulfil their desires to have children.”

    Difficulty conceiving is just one barrier. At the heart of South Korea’s population woes are a raft of social and financial pressures – from patriarchal norms that place most childcare responsibilities on women to long work hours and high education costs – which discourage many young people from having children.

    For some, however, those dreams have merely been delayed. More than half of South Koreans say they want kids but can’t afford them, according to a UN report. And by the time South Korean women have their first child, their average age is 33.6 – among the highest in the world.

    “Looking back, it might have been better to start earlier,” says Ms Park. “But realistically… now actually feels like the right time. In my late 20s, I just didn’t have the financial capacity to think about marriage or kids.”

    The same goes for Ms Kim, who spent three years saving up for marriage and another four for a child.

    “People spend their youth studying, job hunting, and spending money to prepare for life. And by the time they’re ready to settle down, it’s often late,” she says. “But the later you wait, the harder it gets [to become pregnant], physically and emotionally.”  For those who opt for IVF, the process of trying to conceive also becomes much more expensive.

    “It’s hard to say exactly how much IVF costs because it varies so much by person and cycle,” says Ms Kim. “It’s a huge and unpredictable expense that can really affect your finances.”


    Continue Reading

  • Independent shops devastated as brand pulls supply

    Independent shops devastated as brand pulls supply

    Alison McCabe A woman with short white hair, a blue and white patterned shirt, and glasses on the top of her head stands, smiling, next to a large display of Jellycat plush toys including rabbits and fishAlison McCabe

    Alison McCabe said she was devastated by Jellycat’s decision

    Jellycat plush toys have been lining the walls at Rumours in Whitby for more than two decades.

    At times, they’ve taken up a third of the North Yorkshire gift shop’s total shelf space. “They’ve always been a good seller,” said manager Joe Orrell, whose father owns the store.

    But last month, Mr Orrell received an email he “couldn’t quite believe”.

    Jellycat, the British soft toy company, told him it would no longer be supplying Rumours. It did not provide a reason.

    “We were absolutely gutted,” Mr Orrell said. Sales of the brand’s toys made up a “significant portion” of the shop’s income.

    Joe Orrell Joe Orrell standing in his shopJoe Orrell

    The BBC spoke to owners and managers from four independent shops who said they had been hurt and surprised when Jellycat abruptly told them it would stop supplying them.

    “Unfortunately we’re not able to support every shop that wants to stock our products and, after very careful consideration, we recently reviewed our relationship with some stores,” Jellycat said in a statement. It put this figure at 100 stores in the UK.

    “We’re truly grateful for their historic support and wish them all the best for the future,” it said, adding it still supplied about 1,200 independent stores.

    Puddleducks, a children’s clothing store in Diggle, near Oldham, had been selling Jellycat toys for close to 20 years.

    The brand had “really taken off” in popularity over the past year, said owner Alison McCabe, and some weeks she sold hundreds of items. She would be “inundated” with messages from customers asking which items her shop had in stock, she said.

    But, after what she described as months of difficulty getting hold of stock, Jellycat contacted her in mid-June telling her it would no longer supply her.

    The emails to stockists who were being cut off were sent on 18 June and appear to be identical in content, apart from the name of the shop. The owners and managers were not addressed by name, with the emails instead addressed to a “Jellycat stockist”.

    “We’re sorry to let you know that, after careful consideration, we’ll no longer be supplying Jellycat products to Rumours,” the email to Mr Orrell, viewed by the BBC, said. This was related to its “brand elevation strategy”, it added.

    “Please do not place more orders as they will not be fulfilled,” the email continued. “Our decision to conclude the business relationship is final and not open to negotiation.”

    Jellycat did not explain in the emails why it cut the businesses off.

    “We can only think that we’re not good enough,” Mrs McCabe said, adding she did not know if she could make any changes to encourage Jellycat to start supplying her again.

    Another group of store owners, who Jellycat says are among the 1,200 still being supplied, were told they would not be what Jellycat called an “official stockist” but their accounts would be “unaffected”. The BBC understands this means Jellycat would still supply them with stock, where available, but would not give them an Official Jellycat Stockist sticker to display in their shop window.

    Included in this group was Erica Stahl, owner of Pippin, a gift shop in Edinburgh. She told the BBC she was “speechless” when she read the email and that she chose to close her account.

    Jellycat told the BBC: “We select our stockists carefully so that we know customers will receive a joyful experience in their stores, and so Jellycat characters can be found throughout the country.”

    Jellycat became a TikTok hit

    Shop owners told the BBC Jellycat’s toys had always been a stable seller, bought as gifts for newborns or by children saving up pocket money. Then, last summer, the brand boomed in popularity.

    The store owners credited this to the toys becoming hugely popular on TikTok and Instagram, with collectors showing off their displays.

    Jellycat toys have also been a growing trend among “kidults” – adults with a strong interest in toys and childish ephemera, such as Lego and Sonny Angels dolls.

    In recent years, Jellycat has become increasingly focused on the theatricality of presenting its products, with big “immersive” displays at some large department stores.

    At Selfridges in London, toys are displayed around a pretend fish and chip van and wrapped up like a take-away by staff.

    Jellycat also opened a “diner” in New York City and a “patisserie” in Paris – all in gentle shades of blue, with shelves of neatly arranged toys, which fans began to post about on social media.

    The brand said presentation was just one factor it considered when reviewing partnerships with stores. Jellycat also told the BBC it had visited all its independent stores in person.

    ‘Dribs and drabs’ of stock

    However, with Jellycat’s rise in popularity, came changes to the availability of stock, the shop owners said.

    Over approximately the last 12 months, since the toys became more of an online trend, Mr Orrell said stock would only arrive in “dribs and drabs” and his shop had had to reduce the size of its Jellycat display. Collectors visiting his store were getting “more and more disappointed” with what was available.

    Andrew Kenyon, co-owner of JAK Hanson, a department store near Wigan, said he would wait months for some orders, or they would arrive incomplete. Customers would travel from around the UK to buy Jellycat toys from his store, but he couldn’t advise customers on when stock was arriving as he didn’t know.

    Shop owners and managers said they felt Jellycat was prioritising its relationships with bigger retailers.

    “It became nearly impossible to even order any of the bestselling stock,” said Miss Stahl.

    “Small independents like myself are only allowed to order from a list of random mismatched odds and ends that the big shops clearly didn’t want,” she said.

    Erica Stahl A composite image: A selfie of a woman, smiling, with shoulder-length brown hair, dark glasses, a green cardigan and a floral green and white top, sat inside a room with walls painted green; A display of soft toys, books and bibs in a gift shopErica Stahl

    Jellycat told Erica Stahl her shop, Pippin, did not qualify as an “official stockist”

    Charlotte Stray, of Keydell Nurseries in Hampshire, agreed. Independent stores were “pushed to the back of the queue” for stock, she said.

    When Keydell Nurseries got the letter in June saying Jellycat would no longer be supplying it, “we weren’t happy, but we’d been disappointed in the last six, eight months over the supply anyway,” Mrs Stray said.

    “We’ve been increasing our supply to both types of stores – small independents and national retailers – at the overall same rate,” Jellycat told the BBC. “Keeping all our partners well stocked remains a challenge, and we’re constantly working behind the scenes to improve how we plan, allocate and deliver stock as fairly and thoughtfully as we can.”

    The company said independent stores would continue to be “as important in our future as they’ve been in our past”.

    ‘It’s left a really sour taste in my mouth’

    Mrs Stray said that by cutting off some stockists, Jellycat was “crushing independent stores”, who had supported the brand from the start and relied on it for a big portion of their sales.

    Customers have said they are not happy about how Jellycat has treated independent stores, with negative comments flooding the brand’s recent social media posts. A post by Miss Stahl on her shop’s Instagram account about Jellycat telling her she did not qualify as an “official stockist” has nearly 50,000 likes, with many commenters criticising the brand’s conduct.

    “I think they’ve really let themselves down,” Bex Christensen, 38, a photographer from North Yorkshire, told the BBC. She’s been collecting Jellycat toys for more than 20 years and “it’s always been from independent shops”, she said.

    Bex also buys the toys for her two children and estimates that, between them, they have about 100 Jellycat toys at home.

    “As a purchaser, it’s made it really difficult because my kids love it – but it’s left a really sour taste in my mouth,” she said. “Jellycat grew off independent businesses.”

    Jellycat told the BBC it was doing more than ever to support the independent stores it works with, and was planning new initiatives and campaigns.

    The stores the BBC spoke to said they were going to stock different plush toys instead.

    Mr Orrell is optimistic about the future of his business.

    “We’ll certainly survive,” he said. “We’ve been going a lot longer than Jellycat have. We’re not too concerned.”


    Continue Reading

  • Mother mourns sons killed in Israeli strike while waiting for aid

    Mother mourns sons killed in Israeli strike while waiting for aid

    BBC Iman al-Nouri weeps while talking about the Israeli strike that killed two of her sons and seriously wounded anotherBBC

    Two of Iman al-Nouri’s five sons were killed on Thursday’s Israeli strike, while a third was seriously wounded

    Iman al-Nouri’s youngest son, two-year-old Siraj, woke up crying from hunger on Thursday and asked to get some nutritional supplements.

    Siraj’s 14-year-old cousin, Sama, agreed to take him and two of his older brothers – Omar, nine, and Amir, five – to the Altayara health clinic in Deir al-Balah, central Gaza.

    “The [medical] point was still closed, so they were sitting on the pavement when suddenly we heard the sound of the strike,” Iman told a local journalist working for the BBC.

    “I went to [my husband] and said: ‘Your children, Hatim! They went to the point.’”

    Family handout Iman al-Nouri's son, AmirFamily handout

    Amir, five, was killed instantly in the Israeli strike, according to Iman

    Warning: This piece contains graphic descriptions of death and violence

    Iman, a 32-year-old mother of five, rushed to the scene after hearing the strike, only to find her sons and niece lying on a donkey cart that was being used to transport casualties to the hospital because there were no ambulances.

    Amir and Sama were among the dead, while Omar and Siraj were seriously wounded.

    “Omar still had some breath in him. They tried to revive him,” Iman recalled. “Omar needed blood, and it took them an hour to get it. They gave it to him, but it was in vain.”

    “Why are they gone? Why? What did they do wrong?” she asked.

    “They had dreams just like any other children in the world. If you gave them a small toy, they’d be so happy. They were just kids.”

    Family handout Iman al-Nouri's son Omar (right) and one of his elder brothersFamily handout

    Nine-year-old Omar (right), pictured with his elder brother, died of his wounds in hospital

    Iman said Siraj’s head was bleeding and he had lost an eye – an image that she cannot now get out of her head.

    “He had fractures in his skull and… according to the doctor, not just bleeding, but [a major haemorrhage] on his brain,” she added. “How long can he stay like this, living on oxygen? Two are already gone. If only he could help me hold on a little longer.”

    Tragically, doctors have said they are unable to treat Siraj.

    “Since yesterday at 07:00 until now, he’s in the same condition. He’s still breathing, his chest rises and falls, he still has breath in him. Save him!” she pleaded.

    Family handout Iman al-Nouri's son, SirajFamily handout

    Iman said doctors had told her that they were unable to treat two-year-old Siraj

    A spokesperson for the US-based aid group Project Hope, which runs the Altayara clinic, told the BBC that the strike happened at around 07:15.

    Women and children were waiting outside before it opened at 09:00, in order to be first in line for nutrition and other health services, Dr Mithqal Abutaha said.

    CCTV footage of the Israeli air strike shows two men walking along a street, just metres away from a group of women and children. Moments later, there is an explosion next to the men and the air is filled with dust and smoke.

    In a graphic video showing the aftermath of the attack, many dead and severely wounded children and adults are seen lying on the ground.

    “Please get my daughter an ambulance,” one woman calls out as she tends to a young girl. But for many it was too late for help.”

    Dr Abutaha said 16 people were killed, including 10 children and three women.

    The Israeli military said it targeted a “Hamas terrorist” and that it regretted any harm to what it called “uninvolved individuals”, while adding that the incident was under review.

    Project Hope said the strike was “a blatant violation of international humanitarian law, and a stark reminder that no one and no place is safe in Gaza”.

    Dr Abutaha said it was “unbearable” when he found out that people were killed “where they [were] seeking their basic humanitarian and human rights”.

    He questioned the Israeli military’s statement on the strike, including its expression of regret, saying that it “cannot bring those patients, those beneficiaries back alive”.

    He also said that the clinic was a UN-recognised, “deconflicted humanitarian facility”, and that no military actions should have taken place nearby.

    Anadolu via Getty Images Palestinians hold out pans at a charity kitchen in the al-Rimal neighbourhood of Gaza City (11 July 2025)Anadolu via Getty Images

    The UN says there are thousands of malnourished children across Gaza

    Iman said her children used to go to the clinic every two or three days to get nutritional supplements because she and Hatim were not able to give them enough food.

    “Their father risks his life just to bring them flour. When he goes to Netzarim [military corridor north of Deir al-Balah], my heart breaks. He goes there to bring food or flour.”

    “Does anyone have anything? There’s no food. What else would make a child scream if he didn’t want something?”

    Israel imposed a total blockade of aid deliveries to Gaza at the start of March and resumed its military offensive against Hamas two weeks later, collapsing a two-month ceasefire. It said it wanted to put pressure on the Palestinian armed group to release Israeli hostages.

    Although the blockade was partially eased in late May, amid warnings of a looming famine from global experts, there are still severe shortages of food, as well as medicine and fuel.

    The UN agency for Palestinian refugees (Unrwa) says there are thousands of malnourished children across the territory, with more cases detected every day.

    Dr Abutaha said Project Hope had also noticed an alarming rise in cases of malnutrition among adults, which they had not observed before in Gaza.

    In addition to allowing in some UN aid lorries, Israel and the US helped set up a new aid distribution system run by the Gaza Humanitarian Foundation (GHF), saying they wanted to prevent Hamas from stealing aid. But since then, there have been almost daily reports of people being killed by Israeli fire while seeking food.

    The UN human rights office said on Friday that it had so far recorded 798 such killings, including 615 in the vicinity of the GHF’s sites, which are operated by US private security contractors and located inside military zones in southern and central Gaza. The other 183 killings were recorded near UN and other aid convoys.

    The Israeli military said it recognised there had been incidents in which civilians had been harmed and that it was working to minimise “possible friction between the population and the [Israeli] forces as much as possible”.

    The GHF accused the UN of using “false and misleading” statistics from Gaza’s Hamas-run health ministry.

    Iman al-Nouri (2nd right), her husband Hatim (right) and two of their sons look at photos on a mobile phone

    Iman said a ceasefire “means nothing to me after my children are gone”

    Dr Abutaha called on Israel to allow in enough food, medicine and fuel to meet the basic humanitarian needs of everyone in Gaza, so that “everyone could have a dignified life”.

    He also expressed concern that people were being given “false hope” that Israel and Hamas could soon agree a new ceasefire deal.

    Israeli Prime Minister Benjamin Netanyahu said on Thursday that an agreement on a 60-day truce and the release of 28 hostages could be just days away.

    But Palestinian officials said on Friday night that the indirect talks in Qatar were on the brink of collapse because of significant gaps remaining on issues like Israeli troop withdrawals and Hamas’s rejection of an Israeli plan to move all of Gaza’s population into a camp in Rafah.

    “Every day they talk about a ceasefire, but where is it?” Iman said.

    “They’ve killed us through hunger, through gunfire, through bombs, through air strikes. We’ve died in every possible way.”

    “It’s better to go to God than stay with any of them. May God give me patience.”

    Continue Reading

  • Inside King Charles’s fiery gathering that shone a light on his beliefs

    Inside King Charles’s fiery gathering that shone a light on his beliefs

    Sean Coughlan

    Royal correspondent

    Ian Jones/The King’s Foundation King Charles III greets an Indigenous leader - an Earth Elder - wearing a headdress and a dazzling robe of blue feathers.Ian Jones/The King’s Foundation

    It wasn’t exactly a run-of-the-mill royal occasion.

    In the sunny gardens of the Highgrove estate, I stood in a circle with King Charles and an eclectic group who were attending his first “Harmony Summit”.

    We raised our arms in honour of nature as we stood around a fire, which was burning within a ring of flowers.

    Presiding over the fire ceremony, in which we rotated as we honoured the north, south, east and west and then Mother Earth, was an Indigenous leader – an Earth Elder – wearing a headdress and a dazzling robe of blue feathers.

    A conch shell was blown. Butterflies flew around the flowers. And, in a concession to modernity, as well as holding up feathers in a blessing for the King, the elder was reading his incantations from an iPhone.

    There were people reaching to the sky, wearing colourful face paint and elaborate necklaces, while I held my palms up self-consciously, melting in my M&S suit.

    Courtney Louise/The King’s Foundation King Charles and delegates at the Harmony Summit in Highgrove. He is draped in a yellow and black patterned scarf and standing between several men in traditional dress including one in a feathered headdressCourtney Louise/The King’s Foundation

    The summit was a celebration of the King’s philosophy of harmony with nature – an inaugural event that the King’s Foundation hopes will become a regular gathering.

    It brought together representatives from Indigenous peoples, including from tribes in the Amazon, along with environmentalists, climate campaigners, organic farmers, herbalists, educators, crafts people and philanthropists.

    For good measure, there was Dwight from the US version of The Office, or at least actor Rainn Wilson, a director of a climate change group.

    There were other visitors from Amazon too. A film crew from Amazon Prime, making a documentary for next year, who were poring over every moment as the sacred smoke coiled up over the apple trees in Gloucestershire.

    The King, in a light summer suit, spoke a few quiet words of welcome, wearing a circlet of feathers and a scarf that had been draped ceremonially around his shoulders.

    Courtney Louise/The King’s Foundation People wearing traditional clothing listen to a speaker (out of shot) at the Harmony Summit Courtney Louise/The King’s Foundation

    A humane, ruminative, humorous and quietly radical figure, he was at the centre of what he hopes will become the first of many such gatherings.

    But it raised the question – and perhaps opened a window – into what the King believes. What is this thoughtful man really thinking about?

    Harmony is the King’s philosophy, it means that we should be working with the grain of nature rather than against it. Or “her” as, he describes nature, in his book on the subject, published in 2010.

    It’s about the inter-connectedness of all life, infused with a strong sense of the spiritual, and the idea that the human and natural worlds can’t be separated.

    It’s the philosophy that stitches together his many different pursuits – on the environment, climate change, sustainable farming, urban planning, architecture, protecting traditional craft skills and building bridges between different faiths.

    According to a source close to the King, it’s “perhaps the single most important part of his eventual legacy”, bringing together different strands of his work that might seem separate into “one philosophical world view about creating a better, more sustainable world for future generations”.

    The King’s views, including on the environment, were “once seen as an outlier, but now many elements have been accepted and adopted as conventional thought and mainstream practice, embraced around the world”.

    In his book on Harmony – A New Way of Looking at our World, the King describes his purpose as a “call to revolution”, and writes that he recognises the strength of the word.

    It’s a broadside against a consumer culture, in which people and the natural world become commodities. He warns of the environmental threats to the future of the Earth. There’s a call to protect traditional crafts and skills and also for a radical change in rejecting modern, unsustainable, exploitative forms of farming.

    If not avant garde, he’s an avant gardener.

    Courtney Louise/The King’s Foundation A woman wearing a blue and white dotted dress smiles as she walks between two stone pillarsCourtney Louise/The King’s Foundation

    If you go for a walk in Highgrove’s gardens there are small hurdle fences, with wooden rods woven around posts. The King makes these himself and this idea of things being inextricably woven together seems to be central to harmony.

    His book moves from the importance of geometry, with patterns rooted in nature, to the designs in Islamic art and the inspiring dimensions of Gothic cathedrals.

    A sense of the sacred in nature, as well as in people, seems to be an important part of this world view.

    At lunch at the Harmony Summit, grace was said by the Bishop of Norwich, Graham Usher.

    The King’s idea of harmony dovetailed with a very deep personal Christian faith, he said.

    “My sense is that he draws much of his energy and ideas from spending time in prayer and contemplation,” said the bishop.

    He said the King sees his role as serving others and a sense of this “is seen in how he is always keen to learn from other religious traditions, building bridges and fostering good relationships built on respect and understanding”.

    Within strands of Christianity, the King is also said to be have been interested in the Orthodox faith and its use of icons.

    Courtney Louise/The King’s Foundation  Delegates gather around a fire at the Harmony Summit in HighgroveCourtney Louise/The King’s Foundation

    A fire was lit within a ring of flowers

    Highgrove itself has an example of the King’s private sense of spirituality. There is a small sanctuary tucked away in the grounds, where no one else goes inside, where he can spend time completely alone with this thoughts.

    It must seem a world away from the ceremonial juggernaut of this week’s state visit by France’s President Macron.

    The focus of this inaugural Harmony Summit was drawing on the wisdom of indigenous people, tapping into their knowledge and pre-industrial ways of working with nature.

    Survivalist Ray Mears was there to welcome representatives of the Earth Elders group, who work to defend the rights of “original peoples”, who have become the threatened guardians of the natural world. They were wearing traditional headdresses, face paint and ornaments, in among the flowers and trees of Highgrove.

    “People’s selfishness has taken them away from nature. They can’t feel the breeze, they’re too focused on the clock,” said Mindahi Bastida, of the Otomi-Toltec people in Mexico.

    The cacophonous modern world has broken our connection with nature, said Rutendo Ngara, from South Africa. She described our era as a time of “loud forgetting”.

    “We all have egos and ambitions. I wanted to be an entrepreneur, I wanted to sell out,” said Uyunkar Domingo Peas Nampichkai, from Ecuador, the co-ordinator for the Amazon Sacred Headwaters Alliance.

    The temptation for him was to sell his land for oil. He decided a different path and explained what “harmony” now meant to him.

    “It’s well-being for all human beings, all living beings, visible and invisible, it’s Mother Nature… Everything is connected and there’s mutual respect,” he said.

    These were people from forests and rivers who talked of the destructive pressures on them, from mining, oil and urbanisation.

    They weren’t pulling punches either. There were speakers warning of how “Europeans” had killed their people and another who said that the much-hyped COP climate change gatherings were full of empty promises that never delivered for grassroots communities.

    Ailton Krenak, from Brazil, talked of rivers that that had been “erased by money” and seeing the dried-up, polluted waterways was like a much-loved “grandfather in a coma”.

    Courtney Louise/The King’s Foundation Head and shoulders picture of Rutendo Ngara at the Harmony Summit. She has dreadlocks and is wearing dark glasses and a green and purple headscarfCourtney Louise/The King’s Foundation

    Rutendo Ngara described our era as a period of “loud forgetting”

    But how can harmony work in such a discordant world?

    Richard Dunne, who runs the educational Harmony Project which uses the concept in more than 100 schools in the UK, has been applying the principles in a place of extreme conflict, the war in Ukraine.

    He’s been taking classes of children traumatised by the conflict, and reconnecting them with nature, taking them to parks and forests for a place to heal.

    “Ukraine is a powerful example of a country that’s in a war they don’t want and they are losing a lot of people. It’s terrible, there’s a lot of pain and suffering. And they want harmony, a future of living well together, so the message of harmony really resonates there,” he said.

    Highgrove, winningly wobbly with its crooked tiles and trees growing through holes in the roof of a shelter, is a lyrical sight on a summer’s day. It’s a model of harmony with nature.

    How does that message work, when you step outside into an often angry, noisy and brutal world?

    What makes the idea of harmony relevant, is that it puts ideas into practice, it’s not just a “thought exercise”, says Simon Sadinsky, executive education director at the King’s Foundation, which teaches crafts skills to a new generation.

    “It’s not just a theoretical concept, it’s not just a philosophy, it’s grounded in practice,” says Dr Sadinsky.

    “There’s a lot of awfulness going on in the world, it’s hard to stay optimistic. You can feel completely powerless,” says Beth Somerville, a textile worker who completed a King’s Foundation course.

    But she says the idea of “harmony in nature” inspires her work and helps to create things which can be both beautiful and functional, in a way that is “all connected”.

    “It does drive me to carry on and have hope,” she says.

    Courtney Louise/The King’s Foundation  Delegates at the Harmony Summit in HighgroveCourtney Louise/The King’s Foundation
    Courtney Louise/The King’s Foundation A man wearing traditional dress holds two black and white feathers and a microphone at HighgroveCourtney Louise/The King’s Foundation
    Courtney Louise/The King’s Foundation King Charles talks with a man wearing what looks like an animal skin capeCourtney Louise/The King’s Foundation
    Ian Jones/The King’s Foundation  Delegates gather round a fire brazier at the Harmony Summit in HighgroveIan Jones/The King’s Foundation

    Continue Reading