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  • Steatotic Liver Disease Prevalent in At-Risk Adults

    Steatotic Liver Disease Prevalent in At-Risk Adults

    TOPLINE:

    Steatotic liver disease (SLD) was highly prevalent among adults with cardiometabolic risk factors, prolonged alcohol intake, or both combined and affected 70% of participants overall. Alcohol-related liver disease (ALD) showed the highest prevalence of elevated liver stiffness, affecting 25% of participants.

    METHODOLOGY:

    • Researchers conducted a prospective study in Denmark to identify the prevalence, fibrosis severity, and determinants of SLD in 3123 participants (median age, 57 years; 50% women) enrolled through electronic invitations between October 2017 and November 2022; 98% of them had at least one cardiometabolic risk factor.
    • They categorised participants into the following two groups on the basis of the type of risk factors they had:
      • Metabolic cohort: defined as having a BMI > 30 and/or type 2 diabetes without a history of prolonged high alcohol intake (n = 1599)
      • Alcohol cohort: defined as having ongoing or prior prolonged high alcohol intake, as defined by an average daily intake exceeding 24 g for women and 36 g for men for more than 5 years, regardless of cardiometabolic risk factors (n = 1524).
    • Liver steatosis was diagnosed using the controlled attenuation parameter, and liver fibrosis was diagnosed using liver stiffness measurements (LSMs). In participants with LSM values ≥ 8 kPa at baseline, fibrosis stage and steatosis were evaluated through liver histology.
    • Three SLD subgroups were defined as those with metabolic dysfunction-associated SLD (MASLD; presence of liver steatosis, at least one cardiometabolic risk factor, and low alcohol intake), metabolic and ALD (MetALD; presence of liver steatosis, at least one cardiometabolic risk factor, and moderate alcohol intake), and ALD (high alcohol intake in those without cardiometabolic risk factors or very heavy intake regardless of the cardiometabolic risk).

    TAKEAWAY:

    • Overall, 70% of participants had SLD, of whom 51% had MASLD, 13% had MetALD, and 6.3% had ALD. More participants in the metabolic cohort than in the alcohol cohort had SLD.
    • Participants with ALD demonstrated the highest disease severity, with 25% vs 12% of those in MASLD and MetALD groups showing LSM values ≥ 8 kPa, and 8% of participants in the ALD group vs 2.8% and 2.6% of those in MASLD and MetALD groups, respectively, had advanced fibrosis.
    • All cardiometabolic risk factors increased the odds of liver steatosis, with high waist circumference emerging as the strongest risk factor (odds ratio, 6.65; 95% CI, 5.36-8.25), and two risk alleles were identified as significant genetic determinants.
    • Higher levels of education and increased physical activity were associated with decreased odds of liver steatosis, and insulin resistance emerged as the most prominent risk factor for elevated liver stiffness.

    IN PRACTICE:

    “Social determinants of health, genetic risk, and lifestyle factors further influence the prevalence of SLD, calling for nuanced management in primary care, particularly in addressing health inequality through preventive care initiatives,” the authors of the study wrote.

    SOURCE:

    This study was led by Camilla Dalby Hansen, Odense University Hospital, Odense, Denmark. It was published online on July 04, 2025, in the Journal of Hepatology.

    LIMITATIONS:

    Electronic invitation-based recruitment likely introduced selection bias and may not represent the general population. The single-centre design and predominantly White participant population limited the generalisability to other ethnic and cultural groups. Prognostic differences among SLD subclasses could not be detected due to the lack of long-term follow-up.

    DISCLOSURES:

    This study received funding from the Novo Nordisk Foundation to the DECIDE project and MicrobLiver, the European Union’s Horizon 2020 to GALAXY and LiverScreen projects, University of Southern Denmark, Region of Southern Denmark, Novo Nordisk Foundation, and AstraZeneca. Some authors reported receiving speaker/consultation fees and research support and being board/advisory board members of various pharmaceutical companies. Two authors reported being co-founders of Evido.

    This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication. 

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  • ‘The Salt Path’ Scandal: Deadline International Insider

    ‘The Salt Path’ Scandal: Deadline International Insider

    Good afternoon Insiders, welcome back to another edition of our weekly newsletter to cap off what’s been a busy week. I’m Max Goldbart. Do sign up here.

    ‘Salt Path’ Scandal

    Gillian Anderson and Jason Isaacs in ‘The Salt Path‘

    Number 9 Films/Shadowplay Features

    What’s in a story?: Up until last Sunday, Gillian Anderson pic The Salt Path, a true-to-life underdog film about a couple made homeless who walk along a South England coastal path, was a local box office hit. Then, The Observer dropped a bombshell investigation, questioning multiple elements of the couple’s story and revealing that the author of the source material, Raynor Winn, was once arrested after being accused of stealing tens of thousands of pounds from her employer. What’s followed has been an almost nationwide debate around truth, fiction and just how far Raynor Winn was able to push the believability of her story. Given that it is supposed to be a raw, honest re-telling of a couple finding light amid disaster, The Observer report called the very essence of the book into question. Having spoken to multiple experts, it also queried Raynor’s husband Moth Winn’s CBD, a debilitating disorder that has an average life expectancy of 6-8 years, and which he has been living with for more than double that period. Both the book’s publisher Penguin and the movie’s producer Number 9 Films said they had undertaken “all due diligence,” yet the messy affair raises interesting questions over just how far these efforts should stretch, and just how far Raynor Winn had been stretching her story. She hit back furiously Wednesday, issuing a lengthy statement partnered with hard medical evidence of Moth Winn’s CBD, while calling The Observer’s report “grotesquely unfair, highly misleading and [seeking] to systematically pick apart my life.” 

    Disney & ITV Deal

    Bob Odenkirk as Uncle Lee in 'The Bear' Season 4

    Courtesy of FX Networks

    ‘Love Island’ meets ‘The Bear’: It’s been a summer of streamer-broadcaster co-operation. The latest American SVoD to land a bedfellow is Disney+, which has struck a landmark deal with ITV that will see a “Taste of Disney+” rail feature on ITVX and vice versa. Content heading to ITV includes The Bear, Andor and The Kardashians, while Love Island, Mr Bates vs the Post Office and Vera head the other way. Karl Holmes, Disney+’s boss in EMEA, told us the secret of the deal’s success will be in its complementary nature, (Less than 10% of Disney+’s audience is over the age of 55, while for ITV the figure is around 40%) while ITV content chief Kevin Lygo labeled the tie-up a “mutually beneficial alliance.” Free-to-air VoD players and U.S. streamers will “come closer in the future,” Holmes said, as he teased more Disney partnerships of this ilk to come. Disney hasn’t been the only big player looking to collaborate. Netflix and France’s TF1 struck a “new kind of partnership” last month that will see the former carry channels from the latter, while Amazon and France Télévisions did similarly for France Télévisions’ streaming service a couple weeks later. The new age is upon us and collaboration between old and new is the name of the game.

    Britain & France Team On Cinema Pact

    Image: Jeanne Accorsini via Getty

    ‘Plein’ sailing: More collaboration, this time between nations, was revealed after French President Emmanuel Macron visited the UK this week. Macron was in Britain to try and strike a UK-France illegal migration deal but his trip offered an opportunity for the two nations’ movie industries to deepen ties. As Macron hob-nobbed with King Charles, Kate Middleton and the Prime Minister, the BFI and France’s CNC signed a Moving Image Co-operation Agreement aimed at fostering closer collaboration between the UK and French film industries. Given the strength of their respective movie sectors, Mel’s dispatch from the BFI Southbank, where the deal was revealed, notes that co-operation of this ilk has not always been straightforward. The two have vastly different financing systems and legislation, while Brexit has been an impediment to collaboration. Never one to miss an opportunity to address a crowd of culture vultures, UK Minister Chris Bryant, who speaks fluent French, waxed lyrical about French cinema, citing Plein Soleil and Les Enfants du Paradis as personal faves.

    Czeching Out Karlovy Vary

    Dakota Johnson in Karlovy Vary

    KVIFF

    Soft power “depleting”: There was some serious star power in town at this year’s Karlovy Vary International Film Festival (KVIFF), with Dakota Johnson, Michael Douglas and Peter Sarsgaard making the journey to the Czech Republic for what is always a lively event. But in one of the more intriguing sessions, Hollywood’s very status as a titan of global cinema was called into question. The latest Nostradamus report from the Göteborg Film Festival, which was unveiled during the Karlovy industry sidebar, found that Hollywood is losing its “symbolic value” in mainstream culture, as it went on to posit that America’s soft power is being depleted despite the appearance of the A-list stars. “The concept of Americanization has been quite challenged for some time,” Göteborg boss Josef Kullengärd told an audience at the KVIFF industry headquarters. This session came after one where more local concerns were aired, as figureheads made impassioned speeches about how far-right purges are threatening cultural sectors in Hungary and Slovakia. Elsewhere, there remained plenty of glitz and glamor. One of the most popular sessions was Fifty Shades star Johnson’s, who had two films at the fest, Celine Song’s sleeper Materialists and Michael Angelo Corvino’s Cannes hit Splitsville. The two modern dating films got Johnson thinking that “dating sucks,” she told an engaged audience. Karlovy coverage can be found here.

    Terry Gilliam Reflects

    Terry Gilliam interview

    Everett/Getty

    No more fights: Nancy sat down with the weird and wacky Terry Gilliam on Monday as he headed to the Umbria Film Festival in Italy, where a screening next weekend of his iconic 1985 dystopian black comedy Brazil will celebrate the film’s 40th anniversary. The Oscar-nominated icon, a former member of the Monty Python troupe, is always happy to speak with honesty and purpose but appears to be mellowing with age. He told us that while he has often courted controversy during a lengthy career, he doesn’t want “any more fights.” His views on the current state of cinema are rather depressing. “It just feels like it’s not a very interesting time,” he added. “I watch movies now, and I see very technically skilled films, but they are not doing anything to make my view of the world different.” That is certainly a thought to ponder. The director has lined up the likes of Johnny Depp, Adam Driver, Jeff Bridges, Jason Momoa and Tom Waits for his next project, Carnival at the End of Days, but financing is proving a challenge. Dive deeper.

    The Essentials

    Charlie Brooker and Annabel Jones

    Getty

    🌶️ Hot One: Black Mirror creators Charlie Brooker and Annabel Jones have exited their Netflix-owned prodco Broke & Bones.

    🌶️ Another One: Kenya’s Oscar entry Nawi: Dear Future Me landed a North American deal.

    🌶️ A third: Netflix promoted Łukasz Kłuskiewicz to run TV and movies out of the growing Central and Eastern Europe hub.

    📈 Analysis: Jake examined how the frequency of UK Culture Sec Lisa Nandy’s interventions with the BBC are sparking concern.

    🏆 Awards latest: Juliette Binoche surprised Brazilian star Wagner Moura with a gong at the Cinéma Paradiso Louvre Festival in Paris.

    📕 Novel ideas: Frankfurt Book Fair is in talks to launch a network of book-to-screen markets at Venice, Busan and Toronto.

    🖊️ Agents: Stalwart UK lit agency Casarotto Ramsay & Associates has appointed leading agent Jodi Shields as Chairwoman.

    🎮 Gaming: The highly-anticipated Esports World Cup kicked off in Riyadh and unveiled a partnership with IMG.

    🏕️ Fest latest: Former BBC News chief James Harding will deliver the prestigious MacTaggart lecture at the 50th Edinburgh TV Festival.

    📣 New voice: Michelle Yeoh will voice the English-language version of Chinese breakout blockbuster Ne Zha 2.

    🍿 Box Office: Saudi action-comedy Alzarfa: Escape from Hanhounia Hell topped the local box office at home in its opening weekend, beating Jurassic World Rebirth.

    🎥 Trail: For 2000 Meters to Andriivka, an intimate depiction of the Ukraine War from Oscar winner Mstyslav Chernov.

    International Insider was written by Max Goldbart and edited by Stewart Clarke.

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  • Gameshows, Cliff Richard and Stalin’s most hated play: the British culture sent behind the iron curtain | Television

    Gameshows, Cliff Richard and Stalin’s most hated play: the British culture sent behind the iron curtain | Television

    One of the biggest TV hits of the 1960s was Double Your Money, a  kind of low-fi precursor to Who Wants to Be a Millionaire?. Its presenter, Hughie Green, was a titan of family entertainment who drew audiences of more than 8 million to the ITV gameshow, in which contestants chose whether to double their prize pot between questions.

    It was, of course, all about the cash, even if TV-rich in those days involved maximum winnings of £1,000 (about £18,000 in today’s money). The show’s baked-in avarice made the entry in the TV Times for 7pm on 8 November 1966 surprising: “Double Your Money visits Moscow with People to People … the first ever western quiz game in the Soviet Union.”

    For two consecutive Tuesdays, millions of Britons watched Green and his sidekick Monica Rose present a heavily adapted version of the show from a rudimentary studio in the House of Friendship, a mock-Moorish castle near the Kremlin that served as a theatre for communist propaganda.

    Subtitled “People to People” in the listings, the show was renamed “Do You Want to Go On?” in Moscow. Money did not feature. Instead contestants competed for points, which could be exchanged for state-made goodies such as toasters and televisions.

    ‘But what impressed me most was the excitement and enthusiasm of the audience’ … Hughie Green and Monica Rose on Double Your Money. Photograph: PA Images/Alamy

    The recordings were beset with technical difficulties. Lights went out, speakers failed. “But what impressed me most was the excitement and enthusiasm of the audience,” recalled show producer Bill Costello in 2018. “To them the show was unusual, different and original and they really got carried away by the competitive spirit.”

    Viewed from today, the export of a British cash-prize gameshow to Moscow seems fanciful, not least given the current state of relations between Russia and the west. Yet they were in keeping with a wider tradition of cold war cultural exchanges from 1955 until the collapse of the Soviet Union in 1991. This soft-power tit-for-tat involved the shipping of entire ballet, opera and theatre companies as respective governments, and a string of impresarios, swept back the iron curtain to reveal the best each side had to offer.

    The cultural contest was instigated in Moscow after the death of Stalin in 1953. His successors quickly set about softening relations with the west. “They needed to open up, but they wanted to open up in a kind of controlled way,” says Sarah Davies, a history professor at Durham University, who is working on a book about these exchanges.

    ‘Everything was exotic’ … The Moiseyev Dance Company. Photograph: University of Southern California/Corbis/Getty Images

    Within weeks of Stalin’s fatal stroke, Lilian Hochhauser, a London impresario with Russian heritage, began to shuttle top dancers and musicians between the countries, including Mstislav Rostropovich, Dmitri Shostakovich and Benjamin Britten. Hochauser, who is now 98, said in 2019 that a mutual cultural appetite that had flourished during the Anglo-Soviet allyship in the second world war had only grown under Stalin. “Everybody wanted to see the folk-dance companies from the Ukraine, the Moiseyev Dance Company,” she told the Times. “Everything was exotic. Because it had been such a closed book for so long.”

    London initially feared the propaganda potential in such swaps and used the British Council to exert its own control. The first sanctioned visit arranged under its auspices came in 1955 when the 30-year-old director Peter Brook took Hamlet to Moscow, with Paul Scofield in the leading role. It was doubly symbolic; Stalin had hated Hamlet. “It had almost been taboo,” Davies says of the play.

    The Soviet regime also sought legitimacy in the patronage of such heavyweights as Scofield, Britten and even Hughie Green. Stars would be given tours of key Soviet sites, captured by news crews whose films could be narrated as each side saw fit. “How do they live, these mysterious human beings, once our wartime allies but always an unknown quantity to us,” a narrator says in clipped English over a 1965 Pathé news film of Olivier touring Moscow, where the National Theatre was staging Othello a year after the Bolshoi had visited London.

    By then, the risks of these exchanges had become dramatically apparent, with the defection of Rudolf Nureyev during a Kirov Ballet tour of Europe. Before that, in 1958, MI5 were caught on the hop when Michael Redgrave secretly met his old Cambridge friend and notorious double agent Guy Burgess during another tour of Hamlet in Moscow. In an intercepted letter to his mother, Burgess said the men had enjoyed “fine gossips” and that Redgrave had been “much better than Paul Scofield” as Hamlet. But such high-profile brushes with scandal failed to close the curtain on the project, which had been formalised in 1959 with the Anglo-Soviet Cultural Agreement between the British Council and its Soviet counterpart.

    It wasn’t all Shakespeare and ballet. Some cultural exchanges continued to take place outside the official agreement. The British Council had no role in the Double Your Money episodes, which were hosted by Moscow Television during a relative thaw, before the Red Army crushed the 1968 Prague Spring, an attempt by Czechoslovakia to loosen Moscow’s grip. This perhaps partly explains the knockabout tone of the TV Times coverage of the enterprise. “Caviar for breakfast? Well, why not? At 7s 6d for a large dollop, it’s a fabulous buy,” wrote Dave Lanning, a columnist and ITV darts commentator, who joined Green for a tour of Moscow.

    In 1976, Cliff Richard became the first major western pop musician to visit Moscow. He later recalled being given an ornate tea urn in exchange for a pair of his blue jeans. To the delight of fans who had devoured bootlegged records by the Beatles et al, more big names followed in the 1980s, particularly during glasnost, Mikhail Gorbachev’s attempts to open up. Elton John made the trip. Billy Joel crowd surfed in Leningrad while draped in the American and Russian flags.

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    Moscow state of mind … Billy Joel performing in Moscow in 1987. Photograph: ABC Photo Archives/Disney General Entertainment Content/Getty Images

    Some culture was considered beyond the pale for longer, most notably modern art. “Because Soviet art was generally socialist-realist, they found western abstract art a bit of a challenge,” Davies says. But, by 1988, James Birch, a provocative 32-year-old London art curator, spied an opportunity. He had befriended Sergei Klokov, an enterprising KGB agent, and conspired with him to put on a Francis Bacon exhibition in Moscow. Birch says the artist, whom he had known since childhood, was buzzing. “He even went out and bought himself a Walkman and learned Russian on cassette,” he says. In the end, the notoriously capricious Bacon decided not to go, but 400,000 Russians filed through the city’s Central House of Artists to see his work.

    Birch and Klokov teamed up again in April 1990, in the dying days of the USSR, to take Gilbert & George to Moscow. The exhibition was another hit, and open to interpretation. While looking at Coming (1983), in which the artists look up at a sky filled with flying underpants, a Russian man told Birch he thought it represented the west invading Russia, with the pants symbolising war planes or parachutes.

    Whether these exchanges played any significant role in hastening the demise of the Soviet Union remains a matter of debate. Davies says cultural figures who appeared through the iron curtain sometimes overestimated their influence. “It was part of this whole triumphalist narrative that the west undermined the Soviet system because we presented this better, brighter alternative, but I think a lot of scholars challenge that,” she says.

    Back in the USSR … Paul McCartney performing in Red Square in 2003. Photograph: Everett Collection Inc/Alamy

    The tradition of cultural exchanges endured after the cold war, and visits continued to serve the Kremlin as an opportunity to sell its legitimacy on an international stage. In 2003, Paul McCartney performed Beatles hits in a landmark Red Square concert. Vladimir Putin, three years into his presidency, was enthusiastic. Over tea, he told McCartney the Beatles’ music had been “like a gulp of freedom … an open window to the world”. When Putin arrived halfway through the gig, McCartney played Back in the USSR, his 1968 parody of western patriotism.

    Two decades later, Putin’s invasion of Ukraine in 2022 has plunged cultural relations into a new ice age. “It reminds me of the Stalin years, when there was no contact at all,” Davies says. But she has noticed a slight softening. In September, the Russian soprano Anna Netrebko is due to perform at the Royal Opera House in London, three years after New York’s Metropolitan Opera dropped her for refusing to denounce Putin, whom she had supported (she later criticised his invasion and sued the Met).

    In the meantime, the battle for ideas is playing out on new stages. Godfrey Cromwell, a hereditary peer and the director of The British East-West Centre, formerly the The Great Britain-USSR Association, says the use of social media as a propaganda tool has become more important than physical exchanges. Such accounts, he says, “can deliver focused messages to far larger audiences at far less cost”.

    Regardless of their diplomatic potential, cultural exchanges have always opened windows to the people behind the regimes. As Bill Costello put it, decades after Double Your Money’s unlikely jolly in Moscow: “It was an incredible experience and a very human one – because underneath all the language problems and differences in culture it certainly proved to me that people are the same the world over.”

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  • Childhood Trauma Predicts Poor Mental Health in Adults

    Childhood Trauma Predicts Poor Mental Health in Adults

    TOPLINE:

    A study showed that increased exposure to childhood trauma was associated with poor mental health outcomes, increased stress, and higher risks for suicide among adults. Stress appraisals and perceived stress mediated this association.

    METHODOLOGY:

    • In this prospective study, 273 adults (mean age, 38 years; 48.4% men; 85% White) completed online questionnaires in two sessions.
    • Researchers assessed the potential associations between childhood trauma (including emotional/physical/sexual abuse and emotional/physical neglect) and outcomes in adulthood related to mental health, suicide risk factors, and stress.
    • Session 1 included the collection of data on demographics, history of childhood trauma, perceived social support, subjective socioeconomic status, and suicide-related experiences.
    • After 1 week, session 2 included the collection of data on daily stress appraisals; severity of depression and anxiety; and perceived stress, defeat, and entrapment.

    TAKEAWAY:

    • Childhood Trauma Questionnaire (CTQ) scores were significantly correlated with stress appraisals, perceived stress, depression, anxiety, defeat, entrapment, social support, and subjective socioeconomic status (P < .01 for all).
    • CTQ scores significantly predicted stress appraisals, perceived stress, depression, anxiety, defeat, and entrapment (P < .001 for all).
    • Childhood trauma had significant indirect effects on mental health and suicide risk factors via stress appraisals (depression, anxiety, defeat, and entrapment; P < .001 for all) and perceived stress (depression, anxiety, defeat, and entrapment; P < .001 for all).
    • Social support, subjective socioeconomic status, and suicide-related history did not moderate the association between CTQ scores and mental health outcomes, stress-related outcomes, and suicide risk factors among adults.

    IN PRACTICE:

    “[The study] findings underscore the enduring impact of childhood trauma on mental health outcomes and suicide risk in adulthood, mediated through its influence on stress appraisals and perceptions of stress encountered in daily life,” the authors wrote.

    “These current findings may inform interventions designed to reduce the negative effects of childhood trauma,” they added.

    SOURCE:

    This study was led by Leizhi Wang, School of Psychology, University of Leeds, Leeds, England. It was published online on June 23 in PLOS One.

    LIMITATIONS:

    This study did not include participants’ current health conditions, potentially leading to confounding. Additional limitations included the lack of a longitudinal study design and lack of objective stress assessments such as the measurement of cortisol levels.

    DISCLOSURES:

    This study did not receive any specific funding, and the authors declared having no conflicts of interest.

    This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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  • Experimental Chinese satellite turns up in unexpected orbit

    Experimental Chinese satellite turns up in unexpected orbit

    HELSINKI —A Chinese Shiyan satellite appears in a low-inclination orbit never before used by the country, after a week-long detection delay and uncertainty over its mission.

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    Andrew Jones covers China’s space industry for SpaceNews. Andrew has previously lived in China and reported from major space conferences there. Based in Helsinki, Finland, he has written for National Geographic, New Scientist, Smithsonian Magazine, Sky… More by Andrew Jones


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  • Unmanned devices tested in South China Sea-Xinhua

    Unmanned devices tested in South China Sea-Xinhua

    An intelligent seawater sampling unmanned aerial vehicle (UAV) departs from the “Xiangyanghong 10” in the northern waters of the South China Sea, July 9, 2025. Chinese researchers successfully carried out scientific tests involving various types of drones, unmanned surface vessels, and autonomous underwater vehicles aboard the “Xiangyanghong 10” in the northern waters of the South China Sea in recent days.

    The “Innovative Integrated Intelligent Systems Expedition,” led by the Advanced Institute for Ocean Research under Southern University of Science and Technology, in collaboration with multiple research institutes, high-tech companies, and science popularization organizations, conducted real-time assessments of the innovation, integration, and intelligence of these unmanned scientific exploration devices. (Xinhua/Zhang Jiansong)

    A thermal-imaging surveillance unmanned aerial vehicle (UAV) takes off from the “Xiangyanghong 10” to conduct scientific research in the northern waters of the South China Sea, July 8, 2025. Chinese researchers successfully carried out scientific tests involving various types of drones, unmanned surface vessels, and autonomous underwater vehicles aboard the “Xiangyanghong 10” in the northern waters of the South China Sea in recent days.

    The “Innovative Integrated Intelligent Systems Expedition,” led by the Advanced Institute for Ocean Research under Southern University of Science and Technology, in collaboration with multiple research institutes, high-tech companies, and science popularization organizations, conducted real-time assessments of the innovation, integration, and intelligence of these unmanned scientific exploration devices. (Xinhua/Zhang Jiansong)

    An unmanned survey vessel conducts scientific research in the northern waters of the South China Sea, July 9, 2025. Chinese researchers successfully carried out scientific tests involving various types of drones, unmanned surface vessels, and autonomous underwater vehicles aboard the “Xiangyanghong 10” in the northern waters of the South China Sea in recent days.

    The “Innovative Integrated Intelligent Systems Expedition,” led by the Advanced Institute for Ocean Research under Southern University of Science and Technology, in collaboration with multiple research institutes, high-tech companies, and science popularization organizations, conducted real-time assessments of the innovation, integration, and intelligence of these unmanned scientific exploration devices. (Xinhua/Zhang Jiansong)

    An aeromagnetic fixed-wing unmanned aerial vehicle (UAV) flies over the “Xiangyanghong 10” to conduct scientific research in the northern waters of the South China Sea, July 9, 2025.

    Chinese researchers successfully carried out scientific tests involving various types of drones, unmanned surface vessels, and autonomous underwater vehicles aboard the “Xiangyanghong 10” in the northern waters of the South China Sea in recent days.

    The “Innovative Integrated Intelligent Systems Expedition,” led by the Advanced Institute for Ocean Research under Southern University of Science and Technology, in collaboration with multiple research institutes, high-tech companies, and science popularization organizations, conducted real-time assessments of the innovation, integration, and intelligence of these unmanned scientific exploration devices. (Xinhua/Zhang Jiansong)

    Chief scientist of the “Innovative Integrated Intelligent Systems Expedition” Lin Jian (C), also dean and chair professor of the Advanced Institute for Ocean Research at Southern University of Science and Technology, supervises operations of scientific research aboard the “Xiangyanghong 10” in the northern waters of the South China Sea, July 8, 2025. Chinese researchers successfully carried out scientific tests involving various types of drones, unmanned surface vessels, and autonomous underwater vehicles aboard the “Xiangyanghong 10” in the northern waters of the South China Sea in recent days.

    The “Innovative Integrated Intelligent Systems Expedition,” led by the Advanced Institute for Ocean Research under Southern University of Science and Technology, in collaboration with multiple research institutes, high-tech companies, and science popularization organizations, conducted real-time assessments of the innovation, integration, and intelligence of these unmanned scientific exploration devices. (Xinhua/Zhang Jiansong)

    Researchers hoist an autonomous underwater vehicle into the sea in the northern waters of the South China Sea, July 8, 2025. Chinese researchers successfully carried out scientific tests involving various types of drones, unmanned surface vessels, and autonomous underwater vehicles aboard the “Xiangyanghong 10” in the northern waters of the South China Sea in recent days.

    The “Innovative Integrated Intelligent Systems Expedition,” led by the Advanced Institute for Ocean Research under Southern University of Science and Technology, in collaboration with multiple research institutes, high-tech companies, and science popularization organizations, conducted real-time assessments of the innovation, integration, and intelligence of these unmanned scientific exploration devices. (Xinhua/Zhang Jiansong)

    The “Xiangyanghong 10” conducts “Unmanned Swarm” scientific research in the northern waters of the South China Sea, July 8, 2025. Chinese researchers successfully carried out scientific tests involving various types of drones, unmanned surface vessels, and autonomous underwater vehicles aboard the “Xiangyanghong 10” in the northern waters of the South China Sea in recent days.

    The “Innovative Integrated Intelligent Systems Expedition,” led by the Advanced Institute for Ocean Research under Southern University of Science and Technology, in collaboration with multiple research institutes, high-tech companies, and science popularization organizations, conducted real-time assessments of the innovation, integration, and intelligence of these unmanned scientific exploration devices. (Xinhua/Zhang Jiansong)

    The “Dolphin 3” surface rescue robot conducts test in the northern waters of the South China Sea, July 9, 2025. Chinese researchers successfully carried out scientific tests involving various types of drones, unmanned surface vessels, and autonomous underwater vehicles aboard the “Xiangyanghong 10” in the northern waters of the South China Sea in recent days.

    The “Innovative Integrated Intelligent Systems Expedition,” led by the Advanced Institute for Ocean Research under Southern University of Science and Technology, in collaboration with multiple research institutes, high-tech companies, and science popularization organizations, conducted real-time assessments of the innovation, integration, and intelligence of these unmanned scientific exploration devices. (Xinhua/Zhang Jiansong)

    A cross-domain robot takes off from the “Xiangyanghong 10” to conduct scientific research in the northern waters of the South China Sea, July 8, 2025. Chinese researchers successfully carried out scientific tests involving various types of drones, unmanned surface vessels, and autonomous underwater vehicles aboard the “Xiangyanghong 10” in the northern waters of the South China Sea in recent days.

    The “Innovative Integrated Intelligent Systems Expedition,” led by the Advanced Institute for Ocean Research under Southern University of Science and Technology, in collaboration with multiple research institutes, high-tech companies, and science popularization organizations, conducted real-time assessments of the innovation, integration, and intelligence of these unmanned scientific exploration devices. (Xinhua/Zhang Jiansong)

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  • Outrage builds over plan to force all Gazans to southern city

    Outrage builds over plan to force all Gazans to southern city

    For Gazans, a 60-day ceasefire being negotiated between Israel and Hamas would be a lifeline.

    A window to bring in large quantities of desperately needed food, water and medicine after severe – and at times total – Israeli restrictions on aid deliveries.

    But for Israel’s defence minister Israel Katz a two-month pause in military operations would create an opportunity to build what he has called a “humanitarian city” in the ruins of the southern city of Rafah to contain almost every single Gazan except those belonging to armed groups.

    According to the plan, Palestinians would be security screened before being allowed in and not permitted to leave.

    Critics, both domestically and internationally, have condemned the proposal, with human rights groups, academics and lawyers calling it a blueprint for a “concentration camp”.

    It’s unclear to what extent it represents a concrete plan of Prime Minister Benjamin Netanyahu’s government or whether it is a negotiating tactic to put more pressure on Hamas in the talks on a ceasefire and hostage release deal.

    In the notable absence of any Israeli plan for Gaza after the war ends, this idea is filling the strategic vacuum.

    Katz briefed a group of Israeli reporters that the new camp would initially house about 600,000 Palestinians – and eventually the whole 2.1 million population.

    His plan would see the Israel Defense Forces (IDF) securing the site from a distance while international bodies managed the area. Four aid distribution sites would be established in the area, he said.

    Katz also restated his desire to encourage Palestinians to “voluntarily emigrate” from the Gaza to other countries.

    But it has not gained traction or support among other senior figures in Israel, and according to reports the proposal even triggered a clash between the prime minister and the head of the IDF.

    Israeli media say the office of the chief of the general staff, Lt Gen Eyal Zamir, made clear the army was not obligated to forcibly transfer civilians, as the plan would require.

    It’s claimed Gen Zamir and Netanyahu were involved in an angry exchange during a recent war cabinet meeting.

    Tal Schneider, a political correspondent at the centrist Times of Israel, said Zamir would be in a strong position to push back because the government “practically begged him to take the job” six months ago – and Netanyahu strongly endorsed his appointment.

    It’s not only the top military brass that is opposed to the idea. There is also consternation among rank and file too.

    “Any transfer of a civil population is a form of war crime, that’s a form of ethnic cleansing, which is also a form of genocide,” IDF reservist Yotam Vilk told the BBC at his home in Tel Aviv.

    The 28-year-old former officer in the Armored Corps is refusing to serve any longer in the army following 270 days of active combat in Gaza.

    He describes himself as a patriot and argues Israel must defend itself but that the current war has no strategy nor end in sight.

    Vilk is also part of Soldiers for the Hostages, a group calling for an end of the war to secure the release of the 50 Israelis still being held captive by Hamas in Gaza, up to 20 of whom are believed to be alive.

    Meanwhile 16 Israeli experts in international law issued a joint letter on Friday denouncing the plan, which they said would constitute a war crime. The letter urged “all relevant parties to publicly withdraw from the plan, renounce it and refrain from carrying it out”.

    The plan has unsurprisingly dismayed Palestinians in Gaza.

    “We completely reject this proposal, and we reject the displacement of any Palestinian from their land,” Sabreen, who had been forced to leave Khan Younis, told the BBC. “We are steadfast and will remain here until our last breath.”

    Ahmad Al Mghayar from Rafah said: “Freedom is above everything. This is our land, we should be free to move wherever we want. Why are we being pressured like this?”

    It’s not clear how much support Katz’s plan has among the general public, but recent surveys have indicated the majority of Jews in Israel favour the expulsion of Palestinians from Gaza.

    One poll published in the left-wing daily newspaper Haaretz claimed as many as 82 per cent of Jewish Israelis supported such a move.

    But there has been curious lack of public support for the proposal among the far-right, including prominent ministers in the coalition Itamar Ben-Gvir and Bezalel Smotrich.

    Both have been vocal proponents of Palestinians leaving Gaza and Jewish settlers returning.

    Tal Schneider said both ministers may still be weighing up giving their backing to the proposal for a mass camp.

    “Maybe they’re waiting to see where the wind blows to see if it’s serious. Both Smotrich and Ben-Gvir are cabinet members and have more access to internal discussions. Maybe they think this is just to put political pressure on Hamas to come to the table.”

    Outside Israel, the proposal for a new camp for all Gazans has attracted widespread criticism.

    In the UK, minister for the Middle East Hamish Falconer posted on social media that he was “appalled” by the plan.

    “Palestinian territory must not be reduced,” he wrote. “Civilians must be able to return to their communities. We need to move towards a ceasefire deal and open a pathway to lasting peace.”

    British human rights lawyer Baroness Helena Kennedy KC told the BBC the project would force Palestinians into a “concentration camp”.

    The description, which other critics including academics, NGOs and senior UN officials have used, holds considerable resonance in light of the role of concentration camps in the Holocaust.

    Baroness Kennedy said the plan – as well as the latest actions of Israel – has led her to conclude Israel is committing genocide in Gaza.

    “I was very reluctant to go there, because the threshold has to be very high. There has to be specific intent for genocide. But what we’re now seeing is genocidal behaviour,” she said.

    Israel has vehemently rejected the charge of genocide and says it does not target civilians.

    The Israeli foreign ministry also told the BBC that “the notion that Israel is creating concentration camps is deeply offensive and draws parallels with the Nazis”. Israel “adheres to the Geneva Convention”, it added, referring to the international regulations governing the treatment of civilians in occupied territories.

    Aside from grim warnings about what might happen, the prospect of a new camp is having an impact on efforts to end the Gaza war.

    Palestinian sources at the ceasefire talks grinding on in the Qatari capital Doha have told the BBC the plan has alarmed the Hamas delegation and has created a new obstacle to a deal.

    Additional reporting by Joyce Liu and John Landy

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  • Advantage Abramowski in ERC Fiesta Rally3 Trophy

    Advantage Abramowski in ERC Fiesta Rally3 Trophy

    Charpentier started the all-Tarmac contest leading Abramowski by seven points. But a mechanical failure for the Frenchman on leg two let in Abramowski for the category win and a maximum haul of 30 points.

    With just next month’s Barum Czech Rally Zlín remaining on the ERC Fiesta Rally3 Trophy schedule, the advantage is Abramowski’s with a Fiesta Rally2 prize drive on JDS Machinery Rali Ceredigion up for grabs for the eventual winner.

    “We was fighting quite tight so it’s a shame for [Charpentier] but it meant we were leading by two minutes, which is quite a lot,” said Abramowski, who turned 19 the day after Rally di Roma Capitale finished.

    Behind Pole Abramowski, Ireland’s Casey Jay Coleman celebrated his maiden ERC Fiesta Rally3 Trophy in second followed another first-time podium visitor, Adam Grahn. The Swede was tackling his first Tarmac rally.

    Martin Ravenščak took fourth on his return to action after skipping ORLEN OIL 81st Rally Poland. Newcomers Hubert Laskowski and Taylor Gill were fifth and sixth respectively.

    Gill, the leader of the FIA Junior WRC Championship, impressed with eight stage wins but dropped out of first place with a fuel pump issue on leg one.

    Adrian Rzeżnik was quickest on Friday evening’s Rome super special but was also hit by a mechanical issue.

    Who won what on Rally di Roma Capitale

    On each ERC Fiesta Rally3 Trophy round, several incentives are handed out. Here’s a reminder of who won what on Rally di Roma Capitale.

    Tymek Abramowski: 12 new Pirelli tyres, voucher for 150 litres of Warter RALLY EVO2 fuel

    Casey Jay Coleman: 6 new Pirelli tyres, voucher for 100 litres of Warter RALLY EVO2 fuel

    Adam Grahn: 2 new Pirelli tyres, voucher for 50 litres of Warter RALLY EVO2 fuel

    The ERC Fiesta Rally3 Trophy, which supports five FIA ERC3 Championship rounds in 2025, concludes on Barum Czech Rally Zlín from 15 – 17 August.

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  • Palm rises for two consecutive weeks on stronger rival oils – Markets

    Palm rises for two consecutive weeks on stronger rival oils – Markets

    JAKARTA: Malaysian palm oil futures rose on Friday and logged its second weekly gain despite higher June stocks, as stronger rival edible oils and a weaker ringgit underpinned the market.

    The benchmark palm oil contract for September delivery on the Bursa Malaysia Derivatives Exchange gained 29 ringgit, or 0.7%, to 4,175 ringgit ($982.35) a metric ton at closing. The contract rose 2.78% for the week.

    “Bursa Malaysia crude palm oil futures opened gap higher today following sharply higher Dalian’s refined bleached deodorized palm olein,” said Anilkumar Bagani, commodity research head at Mumbai-based brokerage Sunvin Group.

    Dalian’s most-active soyoil contract increased 0.73%, while its palm oil contract gained 0.63%. Soyoil prices on the Chicago Board of Trade (CBOT) fell 0.64%.

    Palm oil tracks the price movements of rival edible oils as it competes for a share of the global vegetable oils market.

    Malaysian palm oil falls on rising June stockpile

    “Malaysia Palm Oil Board data on Thursday was slightly bearish, but the market has ignored it, in view of the delayed shipments from June into July would accelerate the total July palm oil export,” Bagani said.

    Malaysia’s palm oil stocks rose 2.41% to an 18-month high of 2.03 million tons at the end of June, industry regulator data showed.

    Meanwhile, exports of Malaysian palm oil products during July 1-10 were estimated to have risen between 5.3% and 12% from a month earlier, according to data from cargo surveyor Intertek Testing Services and inspection company AmSpec Agri Malaysia.

    Oil prices were stable on Friday on a weaker market outlook for this year by the International Energy Agency (IEA) despite tightness in the prompt market, U.S. tariff concerns and possible further sanctions on Russia.

    Stronger crude oil futures make palm a more attractive option for biodiesel feedstock.

    The ringgit, palm’s currency of trade, weakened 0.12% against the dollar, making the commodity cheaper for buyers holding foreign currencies.

    Palm oil is likely to break support at 4,134 ringgit per ton and fall towards the 4,072-4,096 ringgit range, Reuters technical analyst Wang Tao said.

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  • FDA rejects Capricor’s Duchenne cell therapy

    FDA rejects Capricor’s Duchenne cell therapy

    Adam Feuerstein is a senior writer and biotech columnist, reporting on the crossroads of drug development, business, Wall Street, and biotechnology. He is also a co-host of the weekly biotech podcast The Readout Loud and author of the newsletter Adam’s Biotech Scorecard. You can reach Adam on Signal at stataf.54.

    The Food and Drug Administration rejected a marketing application from Capricor Therapeutics for a cell therapy to treat Duchenne muscular dystrophy, the company said Friday. 

    In its letter to Capricor, the FDA said the company’s application “does not meet the statutory requirement for substantial evidence of effectiveness” and requested additional clinical data, the company said. 

    Capricor submitted a marketing application to the FDA at the end of December. Its off-the-shelf cell therapy, called deramiocel, would have been the first treatment cleared specifically for the cardiomyopathy, a serious heart condition, that is associated with Duchenne. It could have also been used alongside other Duchenne drugs or gene therapies. 

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