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  • Bluetongue disease confirmed on several farms in southern Spain’s Granada province

    Bluetongue disease confirmed on several farms in southern Spain’s Granada province

    Sara Bárcena Hernández

    Granada

    Monday, 1 September 2025, 17:28

    Bluetongue disease is showing no mercy to livestock farmers in Granada province in Spain’s Andalucía region this year. On one of the first farms where the outbreak was detected in the province, located in Órgiva, which warned of possible symptoms back in July, this infectious disease transmitted by mosquitoes has affected 80% of the livestock, which numbers around 650 animals.

    Ten animals have already died – eight sheep and two goats. Experts have already warned that serotype 03 is the most lethal and in Granada province it is already present in at least 28 herds, three of which have been officially confirmed.


    Bluetongue has affected 80% of the livestock on the farm in Órgiva where the first outbreak was confirmed.


    Pepe Marín

    The results of the analyses carried out by the veterinarians of the regional agricultural office (OCA) of the Junta de Andalucía regional government revealed the first outbreak of bluetongue on the same farm in Órgiva, located in Los Tablones, around two weeks ago. SUR’s sister newspaper Ideal visited the farm on Thursday 28 August to see first-hand the situation that has affected farmers including Oliberto Romero, who has more than 400 sheep and 200 goats as well as chickens.

    “When they are sick, you can tell very quickly. Their temperature rises so high that they fall, they can’t walk and they can’t drink water because their tongues swell up”

    Behind the first fence, dozens of sheep are walking and bumping into each other. One of them is visibly ill. “Even the wool is changing from the fever, even the hooves. When they’re sick you can tell very quickly. Their temperature rises so high that they fall, they can’t walk and they can’t drink water because their tongues swell up. It’s a disease that attacks the lungs. Many of them suffocate and even abort,” explains Oliberto, who has been doing the job for thirty years.

    But he says, “the worst is over”. For a month, there were new sick sheep every day. “Twenty or thirty that the night before were eating grass as if nothing had happened, the next day they would wake up swollen and lying on the ground,” he says. Beyond the 10 dead animals, “which at the end of the day is 100 euros per animal, about 1,000 euros in total”, what worries him most is that there may be 100 that have aborted. “It’s a ruin, between the dead and the miscarriages there is no business”.

    “Whoever is here is because they like it, it’s like a drug, not just a business. The problem is that we are alone, that the authorities don’t help us”

    He sells exclusively lamb and goat, kid, but now he can’t do so. The vets insist that the disease is not contagious and does not affect the final product, “but for the moment we are restricted” Oliberto says. He adds that it is impossible to put an “estimate” on the financial losses and says, “Whoever is here is because they like it, it’s like a drug, not just a business. The real problem is that we are alone, that the administration does not help us. They tell us to vaccinate against serotypes 03 and 08 – our herd is vaccinated against 01 and 04 – but they don’t provide the means,” he says.

    Almegíjar also affected

    A second outbreak of bluetongue has been confirmed in Almegíjar, near Torvizcón, also in the Alpujarra. There, veterinarians from the OCA of Órgiva predict the “worst prognosis”. The farm is run by José Miguel García, who has been a livestock farmer for 40 years and has 350 animals. In this outbreak, 34 animals have died, “but I’ve been through it before”, García says, who is convinced that the enclave where he is located is “prone” to the reproduction of the Culicoides mosquito.


    Although the disease mainly affects sheep, goats have also had symptoms.


    Pepe Marín

    “2007 was the first time there were symptoms here. I didn’t know it then, I put it down to autumn. Two years ago, in November, the second time. But I just vaccinated the ill sheep and the disease stopped. It was serotypes 01 and 04,” he recalls. Now, 03 is attacking and it is proving “fatal”.

    While Oliberto says that “there is no estimate”, José Miguel calculates, “roughly speaking”, 12,000 euros lost

    From his farm in Almegíjar José Miguel sells lamb and lamb of “very good” quality. With bluetongue, between 35 and 40 animals have died and now there are another 10 “weaker” ones. “The animals are having a hard time and so am I. I have the sheep because I like to keep them. If they abort, you spend a year working for nothing. It could be 10,000 or 12,000 euros lost, roughly speaking,” he says. He also hopes that there will be help. There should be, he insists. “Bluetongue hits hard those of us who are unlucky enough”.

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  • Brainstem Map Reveals How Pain Is Controlled by Region

    Brainstem Map Reveals How Pain Is Controlled by Region


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    A study has revealed that the human brainstem contains distinct regions for managing pain depending on where it occurs in the body. Researchers from the University of Sydney identified this spatial organization by inducing placebo pain relief and tracking brain activity using high-resolution neuroimaging.

    The results, published in Science, may provide a framework for developing more targeted, non-opioid treatments for chronic pain.

     “This is the first time we’ve seen such a precise and detailed pain map in the human brainstem, showing us that it tailors pain relief to the specific part of the body that’s experiencing it.” 


    Dr. Lewis Crawford.

    Placebo effects reveal spatially-organised pain control

    Researchers enrolled 93 healthy volunteers and used heat stimuli to simulate pain in different body areas. A placebo cream was applied, and the temperature of the stimulus was quietly reduced, training participants to associate the cream with pain relief.

    Later, participants received the same level of pain stimulation on both the placebo-treated area and an untreated control area. A majority of individuals continued to report lower pain in the area previously exposed to the placebo cream, indicating a maintained placebo response.

    During these tests, researchers used 7-Tesla functional magnetic resonance imaging (fMRI), a form of high-resolution brain scanning, to observe brainstem activity. They found that two key areas – the periaqueductal grey (PAG) and the rostral ventromedial medulla (RVM) – were involved in mediating pain relief. Importantly, different subregions were active depending on whether the pain was located on the face, arm or leg.

    Periaqueductal grey (PAG)

    The periaqueductal grey is a region of grey matter located around the cerebral aqueduct in the brainstem. It is involved in modulating pain and coordinating defensive behaviors.

    Rostral ventromedial medulla (RVM)

    The rostral ventromedial medulla is a part of the medulla oblongata in the brainstem. It works with the PAG to regulate the transmission of pain signals to the spinal cord, making it a critical structure in pain modulation.

    7-Tesla fMRI

    7-Tesla functional magnetic resonance imaging is a high-resolution imaging technology that uses a magnetic field strength of 7 Tesla.

    Activity in the upper sections of these structures was associated with facial pain relief, while lower regions were engaged when pain was induced in the limbs.

    The brain’s pain relief is anatomically specific

    The study challenges the idea that the brain’s pain regulation system functions as a single, uniform mechanism. Instead, it suggests that pain control is anatomically mapped, with localized brainstem activity tuned to the part of the body experiencing pain.

    “The brain’s natural pain relief system is more nuanced than we thought. Essentially, it has a built-in system to control pain in specific areas. It’s not just turning pain off everywhere; but working in a highly coordinated, anatomically precise system.”     


    Dr. Lewis Crawford.

    This organization may explain why placebo effects are limited to areas where the brain expects relief. The spatial patterning observed in the PAG and RVM supports a model of targeted neuromodulation rather than global suppression.

    Implications for future pain therapies

    The researchers suggest that this newly identified brainstem map could guide the development of therapies that activate specific circuits without producing systemic effects. Such treatments may be particularly beneficial for individuals with localized chronic pain.

    The findings also raise questions about the neurochemical basis of placebo analgesia. Contrary to previous assumptions that placebo effects operate through the brain’s opioid system, this study points to the lateral PAG – a region thought to be more closely associated with cannabinoid signaling – as a key site of non-opioid placebo analgesia.

    Placebo analgesia

    Placebo analgesia refers to the reduction of pain following the administration of a substance or procedure with no therapeutic effect. 

    By identifying where and how pain relief occurs in the brain, the research highlights a possible role for cannabinoid-based pathways in targeted pain control.

    Reference: Crawford LS, Tinoco Mendoza FA, Robertson RV, et al. Somatotopic organization of brainstem analgesic circuitry. Science. 2025;389(6763):eadu8846. doi: 10.1126/science.adu8846

    This article has been republished from the following materials. Note: material may have been edited for length and content. For further information, please contact the cited source. Our press release publishing policy can be accessed here.

    This content includes text that has been generated with the assistance of AI. Technology Networks’ AI policy can be found here.

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  • Bangladesh crush Netherlands to clinch T20 series – France 24

    1. Bangladesh crush Netherlands to clinch T20 series  France 24
    2. Bangladesh vs Netherlands, 2nd T20I  Cricbuzz.com
    3. Nasum, Taskin and Tanzid help Bangladesh go 2-0 up  ESPNcricinfo
    4. Still A Long Way To Go, But I Am Getting Better, Says Taskin After Four-fer Against Netherlands  Cricketnmore
    5. Netherlands all out for a meagre 103 against Bangladesh  Gulf News

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  • ‘A very tough outcome’ – Fred Vasseur laments double Ferrari retirement in 2025 Formula 1 Dutch Grand Prix but upbeat for Monza

    ‘A very tough outcome’ – Fred Vasseur laments double Ferrari retirement in 2025 Formula 1 Dutch Grand Prix but upbeat for Monza

    Ferrari Team Principal Fred Vasseur admits that a double retirement for the team in the Dutch Grand Prix was “a very tough outcome”, but that the Scuderia “don’t need to have extra motivation for Monza” this weekend.

    Both Lewis Hamilton and Charles Leclerc’s races at the Zandvoort Circuit on Sunday came to an abrupt end at the banked Turn 3 following crashes, leaving Ferrari point-less in the first race back after the summer break.

    Hamilton retired after losing control of his car over the painted advertising as light rain fell before hitting the barrier on the outside of the circuit.

    “I think he was just a bit wider than the previous lap and probably with the drizzle that we had at this stage the track was a bit damp. He lost the car,” said Vasseur on Hamilton’s incident.

    The Briton was also handed a five-place grid penalty for the Italian Grand Prix this weekend after a yellow flag infringement on reconnaissance laps to the grid at Zandvoort.

    Leclerc’s race ended after contact from behind by Kimi Antonelli, the Mercedes rookie handed a 10-second penalty for the incident on Lap 52.

    Leclerc had also been placed under investigation for contact with the second Mercedes of George Russell earlier in the race after an audacious overtake at Turn 11/12, with the stewards eventually deeming that no further action would be taken.

    Vasseur agreed that it was a racing incident and was encouraged by the team’s pace despite the overall outcome, especially after a difficult Friday where both cars were off the pace.

    “The race pace today was good, we overtook two times George on track, we were catching up on Max [Verstappen in third] and score zero at the end,” he said.

    “It’s a very tough outcome for the team because for the championship and even for the approach of Monza it’s not the best one. But for sure if we want to do better a job, we have to do a much better Friday.

    “For sure it’s not the best preparation but on the other hand we don’t need to have extra motivation for Monza.

    “Everybody will push. What we have to do for sure is a much better Friday to put us in a better shape for the Quali and for the race because when you start behind you have to overtake, you have to take risk.”

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  • Tristan da Silva Scores 25 to Lead Germany to Dominant Win Over Great Britain – NBA

    Tristan da Silva Scores 25 to Lead Germany to Dominant Win Over Great Britain – NBA

    1. Tristan da Silva Scores 25 to Lead Germany to Dominant Win Over Great Britain  NBA
    2. NBA duo leads Germany to historic 63-point win in EuroBasket  BasketNews.com
    3. Historic EuroBasket triumph for Germany over Great Britain  Eurohoops
    4. Germany stay perfect with biggest win since 1969  fiba.basketball
    5. $ EUROBASKET $ Here’s Way To Watch Germany vs Great Britain 𝐋𝐈𝐕𝐄 Free 𝐒𝐭𝐫𝐞𝐚𝐦𝐬 ON Tv Channel  MyCentralOregon.com

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  • A very democratic orchestra – DW – 09/01/2025

    A very democratic orchestra – DW – 09/01/2025

    The Deutsche Kammerphilharmonie Bremen and Joseph Haydn (1732–1809), the great composer of the Viennese Classical period, are the subject of the documentary film, “The Haydn Expedition,” which is being shown in the Hall 424 convert venue in Hamburg Harbor.

    The musicians in the film, headlined by Estonian conductor Paavo Jarvi, perform the second movement of Joseph Haydn’s String Quartet Op. 76, No. 3. The quartet movement’s melody was the musical template for the German national anthem, which begins with the words “Unity, justice, and freedom” — symbolic of the democratic themes underlying the film.

    The Deutsche Kammerphilharmonie Bremen (DKB) is seen by many in the field of classical music as a role model due to its democratic organization and financial independence.

    For Albert Schmitt, managing director of the orchestra, this democratic foundation has helped drive the orchestra’s success — alongside the virtuosity of its 41 musicians.

    “The democratic approach creates the basis for each individual musician to identify with the orchestra as much as possible,” Schmitt said. “Everyone has a voice, everyone has the opportunity to contribute; and everyone is therefore constantly motivated to perform at their best.”

    A sign sitting above a river reads 'The Haydn Expedition'
    ‘The Haydn Expedition’ is screening in HamburgImage: DW

    From hippies to a professional orchestra

    In 1980, the orchestra was founded by music students with the aim of making all decisions from the grassroots up. All members have a say about the selection of pieces to play, the choice of conductor, and the musicians who should be invited to perform.

    “We nurtured democracy from an early age because we were looking to structure an orchestra in such a way that it belonged to the musicians, that the musicians were and would remain the owners,” Schmitt explained of the DKB.

    Though once likened to a hippie commune, the orchestra has become more professional. In 1999, the musicians decided to restructure the orchestra into a corporation, and became responsible for their own financial management. Today, the DKB generates around 75% of its income from ticket and recording sales as well as sponsorship revenues, the balance coming from government subsidies.

    Love at first sight

    But democracy can also be exhausting. “Everyone here has their own opinion, especially when it comes to artistic decisions,” said violist Friederike Latzko, who has been with the ensemble since the start. “There’s intense discussion, and we all think that things ought to move much faster, but faster processes aren’t always better.”

    The orchestra brings in high-profile conductors, produces more ambitious concerts, and is performing in more international venues.

    In 2004, the DKB appointed Estonian conductor, Paavo Jarvi, as its artistic director.

    “It was love at first sight,” said Jarvi. From the outset, the conductor has appreciated the orchestra’s working methods and structures.

    “In a normal orchestra, musicians have rights,” said Jarvi . “But in the Deutsche Kammerphilharmonie, they have rights AND responsibilities.” With Järvi  at the helm, the DKB has become one of the best orchestras in the world that’s renowned for its precision, transparency and democratic spirit.

    a bald man conducts an orchestra of women and men plazing violin
    Paavo Jarvi conductsd the orchestra in ‘The Haydn Expedition’Image: DW

    Showing that Joseph Haydn’s music isn’t boring

    In the documentary film, “The Haydn Expedition,” by director Christian Berger, a production by Deutsche Welle in collaboration with broadcaster, NDR, musicians reject the claim that Joseph Haydn’s music is boring. The film shows the passion and precision with which the musicians interpret Haydn.

    The musicians and their conductor had decided — democratically, of course — to first perform Joseph Haydn’s 12 London Symphonies in concert and then record them later in the studio.

    Before Joseph Haydn composed his London Symphonies, he was employed for many years at the court of Nikolaus II, Prince Esterházy in Vienna, a renowned patron of the arts.

    When his patron died, a new life began for the 58-year-old Haydn: The court orchestra was disbanded and he became a freelance composer. He accepted an invitation to London, where he was celebrated, gave major concerts, and composed masterpieces, including the London Symphonies. And it is precisely this freedom that the musicians of the DKB have also laid claim to.

    Democracy: ‘The best system we have’

    During the panel discussion in Hamburg that accompanied the film screening, businessman Michael Otto, a long-time supporter of the DKB, spoke out strongly against top-down management, and in favour of inclusive democratic mechanisms.

    “Today it is much more important for a team to play an active role and for a manager to simply create the framework conditions rather than authoritatively dictating from above what needs to be done,” he said. 

    Peter Limbourg, Director General of Deutsche Welle, who also participated in the panel discussion, spoke of a democracy that’s both valuable and vulnerable.

    “Democracy is under pressure worldwide, but it is still the best system we have,” he said, refering to its inherent checks and balances.

    This is the hallmark of the DKB’s approach: “The orchestra brings the values of democracy, transparency, and cooperation to the world,” Limbourg explained.

    The Haydn Expedition — Joseph Haydn rediscovered

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  • Serum metabolites as diagnostic biomarkers for preterm labor: a metabolomics-based study | BMC Pregnancy and Childbirth

    Serum metabolites as diagnostic biomarkers for preterm labor: a metabolomics-based study | BMC Pregnancy and Childbirth

    Study participants and research design

    This retrospective case–control study included 46 pregnant women with signs of preterm labor who underwent regular prenatal care at Jiangxi Maternal and Child Health Hospital between January 1, 2021, and December 31, 2022. Participants were divided into a preterm birth group (less than 37 weeks of gestation) and a control group (37 weeks or more) based on gestational age at delivery. Inclusion criteria were singleton pregnancies between 28 and 37 weeks of gestation with either regular (at least four contractions in 20 min or eight in 60 min with cervical changes) or irregular uterine contractions, as irregular contractions may progress to preterm birth. Exclusion criteria included multiple pregnancies, gestational hypertension, chronic hypertension, gestational diabetes, fetal growth restriction, autoimmune diseases, and incomplete medical records.

    Peripheral venous blood (5 mL) was collected before any clinical intervention, centrifuged at 3000 rpm for 10 min, and the upper serum layer was stored at − 80℃. The study was conducted by the Declaration of Helsinki and was approved by the Institutional Review Board of Jiangxi Maternal and Child Health Hospital (Ethics Approval No. EC-KT-202207). Written informed consent was obtained from all participants. Obstetric diagnoses were independently reviewed and confirmed by two senior obstetricians.

    Clinical data collected included maternal age, body mass index, gravidity, parity, gestational age at sampling, interval since last delivery, and cervical length measured via transvaginal ultrasound. Laboratory data included complete blood count (white blood cells, red blood cells, platelets, neutrophil count and percentage, lymphocyte count and percentage, and red cell distribution width standard deviation), liver function tests (alanine aminotransferase, aspartate aminotransferase, total protein, albumin, alkaline phosphatase, and lactate dehydrogenase), and renal function indicators (creatinine and urea).

    Reproductive tract health was evaluated through vaginal discharge tests and vaginal microbiota analysis. These assessments are important indicators of female reproductive health, reflecting the microbial balance of the vaginal environment, including bacterial species, quantity, pH, and cellular composition. Vaginal cleanliness is classified into four grades, which are directly related to the risk of gynecological diseases and are valuable for clinical diagnosis and treatment [20].

    Blood samples were analyzed using the Sysmex-XN-2000 automated hematology analyzer (Sysmex Europe, Germany). Liver and kidney function were assessed by radioimmunoassay on the AU5800 automated biochemical analyzer (Beckman Coulter, USA) to exclude the influence of systemic disease on metabolic outcomes. Vaginal tests were conducted using the LTS-V400 automated vaginal infection analyzer (Guokang, Shandong, China) with Swiss staining and combined morphological and dry chemical methods.

    Neonatal outcomes, including birth weight, Apgar score, and gestational age, were recorded by two experienced neonatologists (Table 1). The study design and grouping are shown in Fig. 1.

    Table 1 Comparison of clinical characteristics between two groups of study subjects
    Fig. 1

    Metabolomics Study Design of Serum Samples from Women with Preterm Labor Signs. Note: This study included a total of 23 samples from women with preterm labor signs and full-term delivery, and 23 samples from women with preterm labor signs and PTB. Metabolomics data processing was conducted using untargeted metabolomics based on HPLC-HRMS, with peak extraction and normalization; compounds were identified based on compound databases. Statistical analysis involved the identification of differential metabolites associated with preterm labor signs, KEGG pathway enrichment analysis, and ROC selection of potential biomarkers

    Metabolite extraction and UHPLC-MS analysis

    After slowly thawing the samples at 4 °C, an appropriate amount of sample was added to a pre-cooled mixture of methanol/acetonitrile/water (2:2:1, v/v), followed by vortex mixing, low-temperature sonication for 30 min, standing at −20 °C for 10 min, and centrifugation at 14000 g at 4 °C for 20 min. The supernatant was then vacuum-dried and reconstituted with 100 μL of acetonitrile–water solution (acetonitrile: water = 1:1, v/v) for mass spectrometry analysis. After vortexing and centrifugation at 14000 g at 4 °C for 15 min, the supernatant was used for injection analysis.

    An Agilent 1290 Infinity LC ultra-high performance liquid chromatography system (UHPLC, Thermo Fisher Scientific, USA) with a HILIC column was used for metabolite separation. The column temperature was maintained at 25 °C, with a flow rate of 0.5 mL/min and an injection volume of 2 μL. The mobile phase composition included A: water + 25 mM ammonium acetate + 25 mM ammonium hydroxide and B: acetonitrile. The gradient elution program was as follows: 0–0.5 min, 95% B; 0.5–7 min, B linearly decreased from 95 to 65%; 7–8 min, B linearly decreased from 65 to 40%; 8–9 min, B was maintained at 40%; 9–9.1 min, B linearly increased from 40 to 95%; 9.1–12 min, B was maintained at 95%. Throughout the analysis, samples were kept at 4 °C in the automatic sampler to minimize instrument signal fluctuations. Samples were randomly analyzed in consecutive order to mitigate the impact of instrumental signal fluctuations. Quality control (QC) samples were inserted into the sample queue to monitor and assess system stability and experimental data reliability.

    After separation, mass spectrometry was analyzed using a Triple TOF 6600 mass spectrometer (SCIEX, USA) in both positive and negative electrospray ionization (ESI) modes. The ESI source settings included the following parameters: Gas1: 60, Gas2: 60, Curtain Gas (CUR): 30 psi, Ion Source Temperature: 600 °C, Ion Spray Voltage (ISVF): ± 5500 V (for both positive and negative modes). The mass range for the first mass spectrometry scan was 60–1000 Da, and for the second, it was 25–1000 Da. The accumulation time for the first mass spectra scan was 0.20 s/spectrum; for the second, it was 0.05 s/spectrum. The second mass spectra scan was performed using data-dependent acquisition (IDA) mode with peak intensity value filtering, with declustering potential (DP) set at ± 60 V, collision energy at 35 ± 15 eV, and IDA settings included a dynamic exclusion range of 4 Da, acquiring 10 fragment spectra per scan.

    Data processing and analysis

    Raw data were converted to.mzXML format using ProteoWizard and processed with XCMS software for peak detection, retention time alignment, and peak area extraction. Statistical analysis was performed after metabolite identification, data preprocessing, and quality assessment.

    To ensure the stability and reproducibility of LC–MS analysis, all serum samples were pooled in equal volumes to generate quality control (QC) samples. One QC sample was injected after every ten test samples during the LC–MS run. Blank samples were also used to assess background noise. Instrumental stability was monitored by evaluating the consistency of retention times and peak areas of representative ions in the QC samples. Metabolic features with a relative standard deviation (RSD) greater than 30% in QC samples were excluded. Signal drift was corrected using a QC-based robust LOESS signal correction algorithm (QC-RLSC) to improve data reliability.

    Orthogonal Partial Least Squares Discriminant Analysis (OPLS-DA) was conducted using SIMCA software version 14.1 (Umetrics, Sweden), and 100 permutation tests validated model reliability. Variable Importance in Projection (VIP) scores were calculated to identify influential variables. Differences in metabolite intensities were assessed using the Mann–Whitney U test, and linear regression was applied to analyze associations between pairs of compounds, both conducted in IBM SPSS Statistics (version 21, IBM Corp., USA).

    Differential metabolites were selected based on VIP > 1.0 and p < 0.05. Correlation and clustering analysis were used to evaluate metabolite relationships and grouping. Identified differential metabolites were subjected to the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis. Finally, ROC curve analysis was performed to assess the diagnostic value of these metabolites in distinguishing between the preterm birth and full-term groups.

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  • Sony is hosting a State of Play showcase for 007 First Light on September 3

    Sony is hosting a State of Play showcase for 007 First Light on September 3

    Sony has lined up its next PlayStation State of Play showcase, and this one is all about a single game. It will focus on , the long-awaited James Bond adventure from Hitman studio IO Interactive. It starts at 2PM ET on September 3 and you can watch it on the PlayStation and channels (there’ll also be a version of the video with English subtitles on ). You can also just hit the play button on the YouTube video above when the time is right.

    The showcase will run for over 30 minutes and it will feature a deep dive into gameplay, including a full playthrough of a young Bond’s first mission. Over on the , IOI said to expect “everything from high-speed car chases to on-foot stealth sequences and shootouts.” Following that, IOI will offer up more details on 007 First Light gameplay. Perhaps we’ll also get a release date or narrower window for the action-adventure game, which is slated to hit Nintendo Switch 2, PlayStation 5, Xbox Series X/S and PC in 2026.

    In the meantime, you can get a taste of just why IOI was able to land this gig by checking out Hitman World of Assassination, a bundle of all three of the main Hitman games from the last decade. , and you can play through the first location for free. It’s also available on PC and consoles.

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  • Series Trailer: “House of Guinness”

    Series Trailer: “House of Guinness”

    Netflix

    Netflix has premiered the official trailer for its new high-profile historical crime drama series “House of Guinness”.

    “Peaky Blinders” creator Steven Knight created the series, which unfolds in 19th-century Dublin and New York.

    The story begins in the wake of the death of Sir Benjamin Guinness, the man responsible for the extraordinary success of the Guinness brewery.

    The series explores the far-reaching impact of his last will and testament on the fate of his four adult children – Arthur (Anthony Boyle), Edward (Louis Partridge), Anne (Emily Fairn) and Ben (Fionn O’Shea).

    In addition, it also impacts the lives of a group of Dublin characters who work and interact with the phenomenon that is Guinness.

    Also starring are Dervla Kirwan (“True Detective: Night Country”), Jack Gleeson (“Game of Thrones”), Niamh McCormack (“Everything Now”), Danielle Galligan (“Shadow and Bone”) and more.

    “House of Guinness” is set to air on September 25th. The series is executive produced by Karen Wilson, Elinor Day, Steven Knight, Martin Haines, Tom Shankland and Ivana Lowell.

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  • Danish Energy Agency Re-Rejects Applications for Feasibility Study Permits Under ‘Open-Door’ Scheme

    Danish Energy Agency Re-Rejects Applications for Feasibility Study Permits Under ‘Open-Door’ Scheme

    The Danish Energy Agency (DEA) has revised the applications for feasibility study permits under the open-door scheme, for which the process was suspended in 2023 and reactivated last year. The DEA has now made new decisions in the cases and maintains the rejection of all 37 applications.

    The DEA put the processing of cases under the open-door scheme on hold in February 2023, saying the granting of permits for offshore wind and other renewable energy projects under this scheme may be in breach of EU law.

    At the beginning of March 2023, the DEA resumed the processing of the Aflandshage and the Frederikshavn offshore wind farm projects as the Danish Ministry of Climate, Energy and Utilities assessed that the establishment permits issued for Aflandshage and Frederikshavn in the autumn of 2022 were not in violation of EU law. The projects were granted feasibility study permits in 2019 and 2018, respectively.

    Later that same month, the DEA resumed the assessment of the Jammerland Bugt, Lillebælt South, Omø South, and Nordre Flint offshore wind farms and, in July 2023, case processing of three offshore wind farms laid out in the then-new Marine Plan and all pending applications for test projects under the open-door scheme.

    In May and June 2024, the Energy Complaints Board overturned a number of decisions rejecting applications for feasibility study permits under the scheme and forwarded the cases to the Danish Energy Agency for reconsideration. 

    The Danish Energy Agency has now made new decisions in these cases and, on 1 September 2025, issued decisions to 37 applicants, including for three applications for offshore wind projects with elements of testing. The applicants have all had their applications for feasibility study permits for offshore wind projects under the scheme rejected.

    “It would be illegal state aid to grant a preliminary exploration permit that gives the applicant exclusive rights to a given sea area if the permit has value for the applicant and there has been no competition for the area. Ultimately, it is about complying with EU state aid rules,” said Stig Uffe Pedersen, Deputy Director General of the Danish Energy Agency.

    With a feasibility study permit under the open door scheme, the applicant obtains a royalty-free exclusive right to investigate the possibilities for and subsequently apply to establish an offshore wind farm in the same sea area.

    The DEA assessed that free feasibility study permits for new commercial offshore wind projects under the open-door scheme have a value and that the permit would therefore entail a waiver of state funds and constitute illegal state aid in the current offshore wind market.

    The assessment is based, among other things, on the bidders’ willingness to pay in connection with the tender for the Thor offshore wind farm in 2021 and the subsequent sharply increasing interest in the open-door scheme, according to the DEA. The Agency said that in addition to this, there had been several postponements of competitive tenders in other countries in Europe in recent years, which have ended with payment from the proponent to the state.

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