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  • Gold climbs over 1% on safe-haven bids as Trump imposes fresh tariffs – Reuters

    1. Gold climbs over 1% on safe-haven bids as Trump imposes fresh tariffs  Reuters
    2. Gold prices rise on Trump tariff threat; platinum, silver outperform  Investing.com
    3. Gold edges higher on softer dollar, trade war intensifies  Dunya News
    4. Gold price in Pakistan: Rates on July 11  FXStreet
    5. Gold News: Trump Tariffs Fuel Inflation Fears as Gold Price Awaits Fed Clarity  FXEmpire

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  • Pneumococcal Vaccine Rates Low Despite Updated Recommendations

    Pneumococcal Vaccine Rates Low Despite Updated Recommendations

    In 2022, the Advisory Committee on Immunization Practices (ACIP) published updated pneumococcal vaccine recommendations.1 The committee recommended adults aged 65 years and older who have not received a pneumococcal conjugate vaccine (PCV) or those whose history is unknown receive a single dose of either the 20-valent PCV (PCV20) or 15-valent PCV (PCV15) vaccines. Additionally, when PCV15 is used, a single dose of the 23-valent pneumococcal polysaccharide vaccine (PPSV23) should follow.

    Pneumococcal Vaccine Rates Low Despite Updated Recommendations / Alernon77 – stock.adobe.com

    However, 21 months after the updated recommendations, fewer than 1 in 7 US adults had received a dose of the PCV20 vaccine and uptake remained low among at-risk or high-risk adults and those without prior vaccination. The data, published in the journal AJPM Focus, highlight the importance of implementing strategies to improve vaccine uptake.2

    “Observed low levels of pneumococcal vaccine uptake among eligible US adults persist despite major US public health goals focusing on increasing their use,” the authors wrote. “Increasing pneumococcal vaccine uptake is especially important in light of the recent COVID-19 pandemic that disrupted routine immunization services and highlighted the vulnerability of adults to respiratory infections.”

    A team of investigators from Avalere Health and Pfizer conducted a study to assess uptake of pneumococcal vaccine recommendations and disparities in uptake across subgroups of adult patients. The retrospective cohort study gathered data from the Optum de-identified Clinformatics Data Mart Database from January 2015 through October 2023. The study also included data from adults aged 65 years and older who were enrolled in the Medicare Advantage program.

    The study cohort included 6.8 million adult patients who were enrolled in a health plan as of January 2022 that contributed data to the Optum database. Approximately 86% were 65 years of age or older, 56% were female, 38% were considered low-risk, 39% were at-risk and 22% were high-risk. Of those, 38% had evidence of pneumococcal vaccination prior to January 2022.

    The study found that the uptake of pneumococcal vaccines 21 months after the updated recommendations was 13.2%, with the highest during the first 6 months being the PPSV23 vaccine. By the end of the study period, use of PCV20 was highest at 9.6%, followed by PPSV23 at 3%, PCV13 at 0.8% and PCV15 at 0.2%. Uptake of the PCV20 vaccine was highest among adults aged 65 to 66 years and lowest among at-risk and high-risk adults between the ages of 19 to 49 years.

    “While pneumococcal disease decreased during the [COVID-19] pandemic, the incidence has since resurged, and with it the potential for vaccination to improve health outcomes as well as reduce the economic burden on the healthcare system,” the authors concluded. “Accordingly, new and/or better uptake strategies involving educational campaigns, improving vaccine access and affordability, strengthening the provider recommendation, and integrating vaccination with other preventive services are needed.”

    READ MORE: Pneumococcal Resource Center

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    References
    1. Kobayashi M, Farrar JL, Gierke R, et al. Use of 15-Valent Pneumococcal Conjugate Vaccine and 20-Valent Pneumococcal Conjugate Vaccine Among U.S. Adults: Updated Recommendations of the Advisory Committee on Immunization Practices — United States, 2022. MMWR Morb Mortal Wkly Rep 2022;71:109–117. DOI: http://dx.doi.org/10.15585/mmwr.mm7104a1.
    2. Averin A, Vietri J, Mohs AA, et al. Uptake of Pneumococcal Vaccines Among United States Adults Following 2022 Update to Recommendations. AJPM Focus. 2025,100384, ISSN 2773-0654. https://doi.org/10.1016/j.focus.2025.100384.

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  • Dalpiciclib Plus Endocrine Therapy Prolonged Invasive Disease-Free Survival in HR+/HER2– Breast Cancer

    Dalpiciclib Plus Endocrine Therapy Prolonged Invasive Disease-Free Survival in HR+/HER2– Breast Cancer

    Dalpiciclib (SHR6390; Jiangsu Hengrui Medicine Co) in combination with endocrine therapy (ET) significantly improved progression-free survival (PFS) in first- and later-line settings for hormone receptor-positive (HR+)/HER2– advanced breast cancer. These data, from a first interim analysis of the phase 3 DAWNA-A trial (NCT03927456), were presented at the 2025 American Society of Clinical Oncology Annual Meeting in Chicago.1

    Breast cancer cells | Image Credit: © sknab – stock.adobe.com

    Dalpiciclib is an oral CDK4/6 inhibitor that targets overexpressed CDK4/6 proteins to interrupt cancer cell proliferation. It is approved in China by the National Medical Products Administration in combination with fulvestrant (Falsodex; AstraZeneca) for the treatment of relapsed/progressed HR+/HER2- advanced breast cancer. As of 2025, it’s not approved by the FDA.2,3

    DAWNA-A is a randomized, double-blind, phase 3 study evaluating dalpiciclib plus ET as adjuvant therapy in 5274 patients (ages 18 to 75) with stage 2 to 3 HR+/HER2– breast cancer and pathologically confirmed ipsilateral axillary lymph node involvement. They were randomized 1:1 to receive either daily dalpiciclib at a dosage of 125 mg (3 weeks on/1 week off for 2 years) plus ET (letrozole 2.5 mg; anastrozole 1 mg; tamoxifen 10 mg; toremifene 60 mg daily for 5 years; n = 2640) or placebo + ET (n = 2634). The trial’s primary end point was invasive disease-free survival (iDFS), with secondary end points including DFS, distant DFS (DDFS), overall survival (OS), and safety.4

    Pre- and perimenopausal patients received LHRH agonists, with use in perimenopausal patients determined at the investigator’s discretion. Stratification factors included menopausal status (pre/perimenopausal vs postmenopausal), clinical stage (2 vs 3), number of involved lymph nodes (<4 vs ≥4), and receipt of adjuvant chemotherapy (yes vs no).4

    At the median follow-up of 20.3 months, patients treated with dalpiciclib in combination with ET achieved superior iDFS compared with the placebo group (HR 0.56, 95% CI 0.43–0.71; 1-sided P < .0001), and these benefits were consistent across subgroups. Additionally, dalpiciclib plus ET was preferred over placebo plus ET by DFS and distant DFS.4

    “The phase III DAWNA-A met its primary end point at the first internal analysis, with significant iDFS benefits with dalpiciclib plus [ET] versus placebo plus [ET],” said Zhi-Ming Shao, PhD, Fudan University Shanghai Cancer Center, in their presentation.4

    The safety profile was favorable, with no deaths due to treatment-related adverse events (TRAEs). Treatment-related adverse events (TRAEs) occurred in 3.7% of patients in the dalpiciclib arm and 1.5% in the placebo arm, leading to treatment discontinuation in 2.1% and 0.8% of patients, respectively.4

    “Our data supports dalpiciclib plus [ET] as a neoadjuvant treatment option for [HR+/HER2–] early breast cancer, especially in Chinese populations,” concluded Shao.4

    REFERENCES
    1. A study of SHR6390 in combination with fulvestrant in patients with HR positive and HER2 negative advanced breast cancer. Updated June 3, 2021. Accessed July 11, 2025. https://clinicaltrials.gov/study/NCT03927456
    2. New CDK4/6 Inhibitor offers benefits for advanced-stage, hormone receptor-positive, HER2-negative breast cancer. Breastcancer.org. November 16, 2022. Accessed July 11, 2025. https://www.breastcancer.org/research-news/new-cdk46-inhibitor-offers-benefits-for-advanced-stage-hormone-receptor-positive-her2-negative-breast-cancer
    3. NMPA approves AiRuiKang® (dalpiciclib) in combination with fulvestrant for the treatment of relapsed/progressed HR+/HER2- advanced breast cancer. Hengrui. January 3, 2021. Accessed July 11, 2025. https://www.hengrui.com/en/media/detail-149.html
    4. Shao ZM, Hao J, Wang S, et al. Dalpiciclib (Dalp) plus endocrine therapy (ET) as adjuvant treatment for HR+/HER2– early breast cancer (BC): The randomized, phase 3, DAWNA-A trial. 2025 ASCO Annual Meeting. Chicago, IL. Abstract 515

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  • Netanyahu flies home without a Gaza peace deal but still keeps Trump onside | Benjamin Netanyahu

    Netanyahu flies home without a Gaza peace deal but still keeps Trump onside | Benjamin Netanyahu

    Benjamin Netanyahu arrived back in Israel on Friday without a ceasefire in the Gaza war despite heady predictions from US and Israeli officials that this week could provide a breakthrough in negotiations. But he did not come home completely empty-handed.

    The Israeli PM’s visit was his third since Donald Trump’s inauguration, with several high-profile meetings at the White House, a nomination for Trump to receive the Nobel peace prize, and suggestions from Trump and the special envoy to the Middle East, Steve Witkoff, that peace could be achieved in a week.

    But as Netanyahu’s trip ended, no clear results had been achieved. Witkoff postponed a trip to Doha on Tuesday as it became clear that the negotiations had not reached a point where they could produce a ceasefire agreement.

    While Netanyahu repeated a refrain that a ceasefire could be announced within days, a deal to bring peace to more than 2 million Palestinians in the Gaza Strip remained elusive.

    “I hope we can complete it in a few days,” Netanyahu said during an appearance on Newsmax, a conservative, pro-Trump news network on Wednesday. “We’ll probably have a 60-day ceasefire. Get the first batch [of hostages] out and then use the 60 days to try to negotiate an end to this.”

    By Thursday, when he attended a memorial service for two Israeli embassy staff killed in Washington, Netanyahu said Israel would not compromise on its demands for Hamas to disband. “I am promoting a move that will result in a significant liberation, but only on the conditions Israel demands: Hamas disarm, Gaza demilitarise,” he said. “If it is not achieved through diplomacy, it will be achieved by force.”

    Several officials suggested during the week that only a single sticking point remained between negotiators in Doha: the extent of a withdrawal by the Israel Defense Forces that would follow the release of some of the hostages being held by Hamas. The White House had pushed back against an initial map that would have left Israel with significant zones of control in Gaza, which Witkoff had compared to a “Smotrich plan”, referring to the hardline Israeli finance minister, Bezalel Smotrich. Israel reportedly redrew that map to make it more palatable to the US administration.

    But Hamas has said there were other disagreements, including negotiations over whether the Gaza Humanitarian Fund, an Israeli and US-backed logistics group, would be allowed to continue to deliver food to the territory (the UN said on Friday that 798 people had been killed trying to reach GHF sites since its introduction in May) and whether Israel would agree to a permanent truce, which it has said it would not. US mediators sought to bridge the gap by telling Qatari intermediaries they would guarantee the ceasefire’s continuation after 60 days as negotiations continued.

    The upshot is that while Netanyahu leaves the US without a ceasefire, he has managed his relationship with Trump through high-profile assurances that he is seeking a peace in Gaza, while maintaining a status quo that members of his rightwing coalition, including the ministers Smotrich and Itamar Ben-Gvir, have said is preferable to a peace deal.

    For Netanyahu, the trip produced images that reinforced Israeli claims there was “no daylight” between him and Trump, and came as the US secretary of state, Marco Rubio, announced a decision to impose sanctions on Francesca Albanese, a UN expert on the occupied Palestinian territories, for urging the international criminal court to investigate Israeli officials and US companies over the Gaza war.

    Trump’s frustrations with Netanyahu appeared to be boiling over a month ago as the US president sought to negotiate a truce between Iran and Israel, which had been trading airstrikes and missile barrages as Israel sought to dismantle the Iranian nuclear programme.

    “I’m not happy with Israel,” he said on the White House lawn. “We basically have two countries that have been fighting so long and so hard that they don’t know what the fuck they’re doing.”

    That recalled remarks by Robert Gates, a former US secretary of defence, about successive White House administrations’ difficulties in managing an ally in the region that also had considerable political influence in the US.

    “Every president I worked for, at some point in his presidency, would get so pissed off at the Israelis that he couldn’t speak,” Gates said.

    But a full breach with the US would have been disastrous for Netanyahu, who is managing his own difficult coalition and has been targeted in a graft investigation at home that was again delayed as a result of his international travel. And, after joint strikes against Iran, the Israeli PM was keen to show that the two men were in lockstep, while giving the Trump administration an opportunity to show it was working toward a Gaza peace.

    Elliott Abrams, the senior fellow for Middle Eastern studies at the Council on Foreign Relations in Washington, said the Trump administration had sought, as it did during the first short-lived ceasefire, to bring “pressure to bear on Israel directly” through discussions with Netanyahu and his chief lieutenant, Ron Dermer, and “trying to bring pressure on Hamas mostly through the Qataris, when there are these talks in Doha”.

    He added: “Whether that pressure is effective is unclear.”

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  • If Beans Bother Your Stomach, These 4 Things Can Help

    If Beans Bother Your Stomach, These 4 Things Can Help

    • If beans bother your stomach, starting with small portions can help your gut adjust.
    • Soaking and rinsing beans can also help reduce gas-causing compounds.
    • Try different types of beans to see if there’s a variety you tolerate better than others.

    You’ve probably heard the silly song about beans being the “magical fruit.” And while it’s meant to make kids laugh, there’s some truth to the jingle. For many, eating beans can lead to uncomfortable side effects like gas, bloating or general digestive upset, but it doesn’t have to be that way. 

    Beans are one of the most cost-effective, accessible and delicious ways to boost your intake of fiber and plant-based protein. They’re also packed with important nutrients like potassium, magnesium, iron and B vitamins. In fact, research shows that people who eat more beans tend to get more of several nutrients most Americans fall short on, including choline, folate and calcium, and tend to have lower body weight and waist circumference compared to those who skip them.

    So, if beans bother your stomach, don’t give up on them just yet. Dietitians shared their favorite simple tricks—from choosing the right bean to how you cook them—to help you enjoy the health benefits of beans without the stomach ache. 

    Start Small

    “If you don’t consume beans regularly, introducing them gradually can help build your gut’s tolerance to them by adjusting the gut microbiome,” says Avery Zenker, RD. One reason why beans can produce an increase in gas is because of their high levels of galacto-oligosaccharides (GOS), a non-digestible, rapidly fermenting carbohydrate.

    While starting small will help reduce symptoms, don’t expect to get off the hook completely if you’re just beginning to add beans into your routine. “Some gas and bloating when initially introducing beans is normal,” says Zenker, who recommends starting with just a quarter cup per day or less as you adjust. Within about two weeks of adding beans to your diet, you should start to notice your gas levels returning to baseline.

    Soak and Rinse Them

    “If you’re cooking dry beans, soak them overnight and discard the soaking water before cooking. This helps remove some of the gas-producing compounds like oligosaccharides,” says Sapna Peruvemba, M.S., RDN. 

    How long should you soak dried beans? Research shows that soaking beans for at least six hours may help reduce the gas-producing GOS content by 10 to 40 percent, depending on the type of bean. After soaking your beans, you’ll want to rinse them thoroughly to remove any GOS that leached into the water. “If you’re using canned beans, rinse them thoroughly under running water to reduce those same compounds and excess sodium,” says Peruvemba. 

    Choose a Different Type of Bean

    If one type of bean seems to cause uncomfortable gas, bloating, or cramping, try switching to a different variety. In one older, small study, 50 percent of participants experienced an increase in gas when adding half a cup of pinto or baked beans to their daily diet, but only 19 percent experienced this symptom when eating lower-fiber black-eyed peas.

    “Lentils (including brown, green and red), mung beans, adzuki beans, fava beans, split peas, edamame and black eyed peas tend to be the easiest to digest and cause the least discomfort,” says Zenker. But, because every person’s gut microbiome operates a little differently, you may have to do some experimenting to see which type of bean you tolerate best. 

    Try a Digestive Enzyme

    The reason GOS causes our stomachs such distress is that we don’t have the enzyme needed to digest it. “Taking a digestive enzyme like alpha-galactosidase with your first bite can help reduce gas and bloating by breaking down the fibers found in beans,” says Keren Reiser, RD.

    In most cases, a digestive enzyme will start working to break down fibers and sugars before they reach the colon, where they would otherwise be fermented by bacteria and release gas as a byproduct. But if you’re eating large amounts of beans, you may still experience some discomfort, even with an enzyme. 

    With any supplement, make sure to check with a healthcare provider before trying something new, and prioritize supplements that are independently verified for safety.  

    Other Tips for Improving Gut Health

    • Go low and slow with fiber: Whether you’re increasing your intake of beans or increasing your overall fiber intake, the key is to avoid too much too fast. “Fiber is so important for optimal gut health, but it really needs to be introduced slowly,” says Liz McMahon, M.P.H., RDN, who recommends starting with small portions of fiber-rich foods and drinking plenty of water. 
    • Try deep breathing before eating: If you’re anticipating an upset stomach, that stress may increase the chances of your worries coming true. Through the gut-brain axis (or the connection between how your gut and brain communicate), psychological stress can disrupt digestion and motility while influencing the gut microbiome. “Try diaphragmatic breathing before eating to help prepare your gut for digestion and ease potential discomfort,” says Amy Brownstein, M.S., RDN. 
    • Go for a walk after eating: “A short walk—just 15 to 30 minutes—after a bean-rich meal can help support digestion and reduce bloating,” says Peruvemba. One small study found that a 10- to 15-minute walk after eating was as effective as prokinetic medication at relieving fullness and bloating symptoms.

    Our Expert Take 

    Beans are a nutrient-rich food with a number of health benefits, but can also cause gas and bloating for some people. The good news is that you don’t have to avoid legumes; you may just need to take a few extra steps to reduce the gas-producing effects of beans. By starting with small portions, choosing a lower-fiber bean, soaking and rinsing them before eating, and using a digestive enzyme if needed, you can comfortably enjoy the health benefits and flavors of beans. 

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  • Venus Williams to make tennis return, aged 45, at Mubadala Citi DC Open 2025

    Venus Williams to make tennis return, aged 45, at Mubadala Citi DC Open 2025

    Seven-time Grand Slam tennis champion Venus Williams is about to make her return to pro tennis at the age of 45.

    The American announced in a press release that she had accepted a wild card to enter the main draw of the Mubadala Citi DC Open 2025, taking place from 21-27 July in Washington, DC.

    A four-time Olympic gold medallist, Venus said, “There’s something truly special about DC: the energy, the fans, the history. This city has always shown me so much love, and I can’t wait to compete there again!”

    Williams’ last match on the WTA Tour was at the Miami Open in March 2024.

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  • Massive 16-Year Study Links Wellbeing to Stronger Memory in Aging : ScienceAlert

    Massive 16-Year Study Links Wellbeing to Stronger Memory in Aging : ScienceAlert

    Want to remember things better as you get older? The secret might be surprisingly simple: focus on feeling good.

    Recent research involving over 10,000 people aged 50 and above has found that people with higher wellbeing perform better on memory tests as they age. The study, which followed participants for 16 years, checked their wellbeing and memory every two years.

    The researchers expected that good memory might improve wellbeing, but found no evidence for that.

    Instead, it was wellbeing that predicted better memory performance over time.

    Related: Surprise Discovery About Sugar in The Brain Could Help Fight Alzheimer’s

    The study also found that the link between wellbeing and memory stayed strong even after taking things like depression into account. This means wellbeing may affect memory on its own, not just through effects on mood.

    You can increase your wellbeing by being present. (diversifylens/Canva)

    However, the study’s authors acknowledge some limitations that should be taken into account when considering the real-life application of their findings.

    The study relied on people reporting their own wellbeing, which can be biased – some people might overestimate how good they feel. The research also can’t prove that wellbeing directly causes better memory – other factors like income or life experiences might play a role.

    Also, the memory tests used were relatively simple and might not capture the full complexities of how memory works in real life.

    Despite these limitations, the study offers a compelling reason to invest in your wellbeing now. Here are five evidence-based strategies to increase the positive emotions in your day-to-day experiences.

    Five strategies to boost your wellbeing now

    1. Be grateful

    Some people feel better when they keep a gratitude journal.

    2. Engage in acts of kindness.

    Being kind can boost the wellbeing of both initiators and receivers of kindness.

    3. Nurture your most important relationships

    Positive relationships are important for our wellbeing. These should be nurtured and maintained.

    4. Be more present.

    In a distracted world, being present in the moment can be difficult. Being present is the opposite of multitasking. This takes intentional practice and you can develop it through meditation or mindfulness practices.

    5. Do things that lead to a “flow” state.

    Being in a flow state means that we are fully engaged in an activity. It is a mental state where a person feels fully involved and enjoys a process or activity that provides just the right balance of challenge and reward.

    People often talk about this as “being in the zone”. Finding an engaging hobby or sport is a good way of increasing flow moments.

    Ensuring that you and the people around you experience positive emotions regularly is not just about feeling good in the moment. It is also an important investment for the future, ensuring better mental health and wellbeing for yourself and others. What will you do?The Conversation

    Christian van Nieuwerburgh, Professor of Coaching and Positive Psychology, RCSI University of Medicine and Health Sciences

    This article is republished from The Conversation under a Creative Commons license. Read the original article.

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  • What does a solar tornado look like? One photographer got these incredible shots

    What does a solar tornado look like? One photographer got these incredible shots

    Thousands of solar tornadoes swirl above the sun’s surface at any given moment. These remarkable photos give us a glimpse at these stunning cosmic phenomena. 

    The entire disc of the sun captured on September 2, 2024, reveals the beauty of solar activity with an unprecedented level of detail and depth.

    Composite Photograph by Miguel Claro

    Photographs byMiguel Claro

    Text byPaola Rosa-Aquino


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  • Steve Garcia | Only Looking Forward

    Steve Garcia | Only Looking Forward

    Luckily, Garcia didn’t have to put his toughness on one wheel on display, as it was Barboza who withdrew from the fight due to injury. It wasn’t the greatest news Garcia heard, but he ultimately got an equally respected foe for this Saturday’s UFC Nashville card when perennial featherweight contender Calvin Kattar was slotted alongside him.

    “I’m excited,” said Garcia. “He’s ranked, and I’m just here, man. I’m just crawling my way through the division.”

    GET YOUR TICKETS: UFC Nashville | UFC 318 | UFC Abu Dhabi | UFC 319

    Thankfully, on two good ankles. As for his willingness to walk into the fire against someone with the weapons to make him pay for his decision, he laughs. 

    “I don’t think a normal person would understand,” said Garcia. “When you fight somebody like Barboza, you have to almost put yourself in this mental spot where it’s kind of dark. In my head, I was like, every time he goes after my leg, I’ve got to make him pay for it. If it’s super severe, then maybe you should probably just withdraw from the fight. But when it’s something that I’ve gone into fights with before and I can still make the weight and I can still carry on a normal fight night, I’m going to take the fight, regardless of who it is. You just bite down on your mouthpiece and let’s go. That’s my mindset. I could easily make things worse with my ankle, but, at the end of the day, I’m not going to stop. I’m not going to quit. I’m going to keep going until my ankle’s literally dangling off my leg. That’s how I see it.”


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  • 2025 Emmys News & Updates: Everything We Know

    2025 Emmys News & Updates: Everything We Know

    Deadline has exclusively reported several submissions for various shows or TV movies including The Last Of Us, Overcompensating, Bridget Jones: Mad About the Boy and more.

    The Last of Us

    The Last of Us Season 2 made 35 submissions for the 2025 Emmys including the Outstanding Drama Series cateogory as well as 10 acting entries as well as four writing and directing entries. At least a third of the overall submissions are for the second episode, titled “Through the Valley” in which a very big character death occurred.

    RELATED: It Starts On The Page (Drama): Read ‘The Last Of Us’ Episode 202 Script “Through The Valley” With Foreword By Craig Mazin

    Speaking of that major character, Pedro Pascal will remain in the Lead Actor in a Drama Series race for his role as Joel Miller, though his character was killed off in Episode 2 of Season 2.

    Bridget Jones: Mad About the Boy

    The fourth film installment in the Bridget Jones franchise, adapted from Helen Fielding’s books, submitted in the Outstanding Television Movie category because it released exclusively on Peacock earlier this year. Star Renée Zellweger will also submit for Lead Actress in a Limited or Anthology Series or Movie for the role that got her an Oscar nomination.

    Overcompensating

    Creator of Overcompensating, Benito Skinner was submitted in the Lead Actor in a Comedy Series, and he will represent the series in a submission for the Outstanding Comedy Series category. Wally Baram will vie for Lead Actress in a Comedy Series, and Adam DiMarco will compete for Supporting Actor in a Comedy Series, along with Rish Shah. Mary Beth Barone and Holmes are up for Supporting Actress in a Comedy Series.

    Kyle MacLachlan, Connie Britton, James Van Der Beek and Charli XCX will vie for Outstanding Guest Actor in a Comedy Series. English singer-songwriter Charli XCX also produces original music for the series.

    The Pitt

    The Pitt star, writer and executive producer submitted for all three roles on HBO’s medical procedural series. He is up for Lead Actor In a Drama Series for his portrayal of Dr. Michael “Robby” Robinavitch, the dedicated senior attending physician at the Pittsburgh Trauma Medical Hospital.

    RELATED: ‘The Pitt’ Season 2 Begins Production; First-Look Photo & Premiere Window Unveiled

    Wyle and series creator, executive producer and showrunner R. Scott Gemmill are the shows two submissions in the Writing for a Drama Series category, while executive producer John Wells, Amanda Marsalis and Damian Marcano are up for Directing In a Drama Series.

    Étoile

    Amy Sherman-Palladino’s series for Prime Video, Étoile, will be submitted in the comedy categories at the 2025 Emmy Awards.

    RELATED: ‘Étoile’ Canceled By Prime Video After Season 1 Of Two-Season Order

    Presumed Innocent

    Season 1 of Apple TV+’s legal thriller Presumed Innocent will compete in the Limited or Anthology Series categories at the 2025 Emmy Awards. The designation has been approved by the TV Academy. The series has been renewed for a second season.

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