Distinct ligands for the same G-protein coupled receptor (GPCR) activate intracellular signaling partners to varying extents, but the molecular mechanisms driving these differences remain elusive. Hypothesizing that such differences in signaling…
Blog
-
Meta’s Threads makes a play for podcasters and their rabid fans
Meta Platforms Inc.’s Threads will launch podcast previews, or the ability to upload snippets of shows that play directly in user feeds, as part of a broader effort to encourage podcasters and their fans to spend more time on the social…
Continue Reading
-
Effects of Non-Alcoholic Fatty Liver Disease on Baseline Histology and
Introduction
Non-alcoholic fatty liver disease (NAFLD), a spectrum of liver disorders, is characterized by excessive hepatic fat accumulation, contributing to the pathogenesis of non-alcoholic steatohepatitis (NASH), progressive fibrosis, and…
Continue Reading
-
Pakistan enhances efforts to promote quality education for better future: minister-Xinhua
ISLAMABAD, Dec. 22 (Xinhua) — Pakistan’s Minister of State for Federal Education and Professional Training Wajiha Qamar said that the country will enhance and improve quality education and professional training nationwide for students,…
Continue Reading
-
Pakistan enhances efforts to promote quality education for better future: minister-Xinhua
ISLAMABAD, Dec. 22 (Xinhua) — Pakistan’s Minister of State for Federal Education and Professional Training Wajiha Qamar said that the country will enhance and improve quality education and professional training nationwide for students,…
Continue Reading
-
Can a binary companion survive a supernova blast?
From the December 2025 issueWhen a supernova explodes, it doesn’t destroy its companion star — or any planets that might be orbiting it.
Continue Reading
-
Joe Ely obituary | Country
Joe Ely was a country-rock pioneer from west Texas who brought a new audience to country music. In Britain, he won over punk fans thanks to his friendship with the Clash, with whom he formed a perhaps unlikely alliance after the band had watched…
Continue Reading
-
K-P schools, colleges to observe zone-based winter holidays
Areas in summer zone to observe holidays from Jan 1 to 15, while vacations in winter zones to be from Dec 23 to Feb 28
Winter holidays for Shangla and…
Continue Reading
-
High-Dose Chemotherapy Outcomes in Testicular Cancer
A large Nordic study has provided new evidence on the role of high-dose chemotherapy (HDCT) with autologous stem-cell support in men with germ cell cancer, a rare but usually highly curable form of testicular cancer. The research, led by the…
Continue Reading
-
Metabolic dysfunction-associated steatotic liver disease and liver fib
Introduction
Cardiovascular-kidney-metabolic (CKM) syndrome is a progressive condition characterized by a complex multisystem interplay involving chronic kidney disease (CKD), cardiovascular disease (CVD), and metabolic risk factors.1 The staging…
Continue Reading