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  • New Clinical Guidance Recommends Vaccines to Protect Cardiovascular Patients From Respiratory Illness

    New Clinical Guidance Recommends Vaccines to Protect Cardiovascular Patients From Respiratory Illness

    The American College of Cardiology (ACC) has issued Concise Clinical Guidance (CCG) recommending vaccines to protect adults with heart disease from respiratory illnesses, including respiratory syncytial virus (RSV), influenza, and COVID-19.1,2

    Image credit: guerrieroale | stock.adobe.com

    “Vaccination against communicable respiratory diseases and other serious diseases is critical for people with heart disease, but barriers exist to ensuring people are educated on which vaccines to get, how often to get them, and why they are important,” Paul Heidenreich, MD, FACC, chair of the CCG writing committee, said in a news release. “With this document, we want to encourage clinicians to have these conversations and help their patients manage vaccination as part of a standard prevention and treatment plan.”2

    Individuals with heart disease face an increased risk of contracting respiratory viruses and experiencing severe outcomes, including hospitalization and death. Although previous studies have demonstrated that vaccines are effective at reducing these risks, a recent study found that only 30% of health care providers, including primary care physicians, are checking their patients’ vaccination status during appointments.1,2

    RSV and Heart Disease

    Older adults and individuals with chronic medical conditions face a higher risk of severe RSV and related cardiovascular complications. Those most vulnerable to RSV include all adults 75 years and older, adults aged 50 to 74 with specific risk factors, and individuals with weakened immune systems or those living in nursing homes. Individuals with chronic medical conditions like lung disease, heart failure, coronary artery disease, kidney disorders, obesity, and certain neurologic conditions are also at an increased risk.3

    According to the American Heart Association, nearly 150,000 adults aged 60 years and older are hospitalized annually in the US due to serious cases of RSV. The virus is known to have significant effects on heart health, including damaging heart muscle, causing inadequate blood supply to the heart, known as ischemia, and increasing the risk of irregular heartbeat, or atrial fibrillation. RSV can also worsen existing heart conditions, such as arrhythmias and heart failure, and is linked to a higher risk of heart attack or stroke, particularly within the first 3 days of infection.3

    Vaccine Recommendations for Respiratory Illness and Heart Disease

    The guidance from the ACC and American Heart Association primarily focuses on respiratory vaccines but also includes information on the herpes zoster vaccine, as previous evidence suggests it may provide cardiovascular benefits. The document outlines strategies to improve vaccination rates and address patient hesitancy and barriers to access.1,2

    RSV

    The RSV vaccine is recommended for adults aged 75 years or older and those aged 50 through 74 years with heart disease, as it protects against lower respiratory disease that could lead to hospitalization or death. The current guidelines advise a single dose of 1 of the 3 approved RSV vaccines—RSVPreF3 (Arexvy; GSK), RSVpreF (Abrysvo; Pfizer), or mRNA-1345 (mRESVIA; Moderna)—for all adults 75 years and older, along with individuals aged 60 to 74 years who are at increased risk of severe illness, instead of an annual vaccination.1,2

    Influenza

    An annual flu vaccination is recommended for all adults, based on the CDC and several cardiovascular societies, confirming its ability to reduce cardiovascular and all-cause mortality and morbidity. However, nasal versions of the vaccine are not suggested for use in patients 50 years and older.1,2

    Evidence for this recommendation is supported by 6 randomized controlled trials and other studies, including a total of 6734 individuals. In the meta-analysis, researchers found that over a 7.9-month follow-up period, vaccine recipients had a 36% lower risk of major adverse cardiovascular events compared to those who received a placebo or no vaccine.1

    Pneumococcal

    The pneumococcal vaccine is recommended as a 1-time dose for adults aged 19 or older with heart disease to protect them from pneumonia, bacteremia, meningitis, and their associated risks of hospitalization and death. Following CDC recommendations, the guidance advises a single dose of either PCV20 or PCV21, or a combination of PCV15 followed by PPSV23, depending on the individual’s prior vaccination history.1,2

    COVID-19

    All adults with heart disease were recommended to receive the seasonal COVID-19 vaccine for the fall 2024 to 2025 season. However, the guidance noted that future COVID-19 vaccination recommendations for all adults may need to be reevaluated if the virus’s severity and prevalence continue to decrease. Despite this, it is likely that vaccination will remain beneficial for individuals with heart disease due to their increased risk of infection, severe illness, heart attack, COVID-19-induced pericarditis or myocarditis, COVID-19-induced stroke and atrial fibrillation, long COVID symptoms, and death.1,2

    Shingles

    Adults aged 50 years and older are recommended to receive 2 doses of the shingles vaccine to protect against stroke and heart attack during infection, as multiple observational studies have found that patients vaccinated for shingles experience a reduction in cardiovascular events. Additional randomized data also shows that the vaccine is as effective, or more effective, for patients with coronary artery disease compared to those with other chronic conditions.1,2

    This document released by the ACC and American Heart Association suggests that discussing vaccination during cardiology appointments could be essential to integrate immunizations into a cardiovascular care plan.1,2

    REFERENCES
    1.A. Heidenreich, P, Bhatt, A, Nazir, N. et al. 2025 Concise Clinical Guidance: An ACC Expert Consensus Statement on Adult Immunizations as Part of Cardiovascular Care: A Report of the American College of Cardiology Solution Set Oversight Committee. JACC. null2025, 0 (0) .https://doi.org/10.1016/j.jacc.2025.07.003
    2. The American College of Cardiology issues vaccine guidance for adults with heart disease. EurekAlert! News release. August 26, 2025. Accessed September 2, 2025. https://www.eurekalert.org/news-releases/1095588
    3. RSV and Heart Health. American Heart Association. News release. Updated July 30, 2025. Accessed September 2, 2025. https://www.heart.org/en/health-topics/rsv

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  • ‘KPop Demon Hunters’ Singer and Songwriter EJAE On Writing ‘Golden’

    ‘KPop Demon Hunters’ Singer and Songwriter EJAE On Writing ‘Golden’

    Both “Golden” and “KPop Demon Hunters” have become a global phenomenon.

    In a nutshell, “KPop Demon Hunters” dropped on Netflix in June, and it exploded. It’s the biggest movie ever to stream on the platform. Four songs from the film’s soundtrack sit on Billboard’s top 10, and the film landed the top spot at the domestic box office – a first for the streamer.

    The film’s “I Want” song “Golden” sung by the fictional K-Pop girl band Huntr/X sits atop the Billboard Top 10 and is undeniably the song of the summer. Countless social media videos show parents playing the song on repeat for their children, and adults have no shame in sharing their sing-along moments for the world to see.

    There’s no escaping “Golden.”

    “KPop Demon Hunters” follows Huntr/X, the fictional K-pop girl group whose members double as demon hunters. When they’re not battling demons and saving the world, they’re lighting up the stage with catchy songs such as “Golden.” However, they face their toughest foe yet, the Saja Boys, a demon boy band who are out to steal Huntr/X’s fans and their souls. Through it all, Rumi, who is half-demon, has to face another demon, one of self-acceptance. Arden Cho, May Hong and Ji-young Yoo provide the speaking voices for Rumi, Mira and Zoey, respectively. EJAE, Rei Ami and Audrey Nuna provide the respective singing voices.

    EJAE, a K-pop singer, is used to hearing her voice on demo tracks; hearing her voice and the songs played everywhere is taking getting used to. “Hearing it at H Mart on the radio. It’s weird,” she says.

    The film’s popularity “hasn’t fully set in” for Cho. At a recent screening, she had a waitlist for her young nieces AND nephews. She understands its mass appeal regardless of age. Cho says, “It allows any human or person to feel like they can relate. It’s like they feel seen.”

    The song is written by: EJAE, Mark Sonnenblick, IDO, 24, and TEDDY. IDO, 24, TEDDY, and Ian Eisendrath are the song’s producers.

    In the movie, “Golden” sets up the idea of Rumi, Zoey and Mira working to protect the world from demons and seal the honmoon, a barrier separating demons from the real world.

    The song blends both English and Korean seamlessly into its lyrics.

    Speaking with Variety, EJAE said, “One of the biggest assets I brought to the movie, or when writing the songs, was being bilingual. It was important for our co-director, Maggie Kang, to have Korean in the lyrics, and I just love that it’s not just the verses; it was in the actual song too.”

    She went on to say that cracking the actual song took a while. While they had a general idea of what the scene needed, the filmmakers gave a guideline: “It needed to have the word gold in it, and the feeling of what Rumi was going through.” It also needed to introduce the struggles of each member in the verses. She says, “It needed a pep talk and the idea that we can do this together.”

    Thematically, it also needed to be empowering and follow the hero’s journey of feeling like an outsider.

    In the song, Rumi’s vulnerabilities are revealed – “She’s incredibly hardworking and has that leadership. She puts her best foot forward, but she tries to hide her imperfections and flaws.”

    EJAE admits the melody was one of the first things she came up with for the song. “That was the first thing that I came up with.” She confesses, “I actually wrote the melody on my way to the dentist.”

    The idea of “gonna be Golden” lyrics came soon after. She took it to Sonnenblick and had mumbled those words to him on the rough takes. His reaction? “Oh my God!” EJAE says the inspiration continued, and they wrote it “super fast.”

    EJAE didn’t just relate to Rumi’s struggles; she related to the words she wrote. As a former K-Pop trainee, that experience and pressure were something she tried to drop into the song’s bridge. Once she had that, she says the bridge too came together with ease. “Going through that experience helped a lot in writing and emoting the melody and lyrics.”

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  • Shooting Splitsville’s Brutally Funny Fight Scene

    Shooting Splitsville’s Brutally Funny Fight Scene

    Some of your most interesting work comes when you feel like you’re skating on thin ice. On Splitsville, director Michael Angelo Covino and I leaned into the imperfections that come with shooting on film with older lenses and doing fewer takes. Riding that razor’s edge of getting the shot or not getting it — we live for that.

    Mike is drawn to French cinema made during the 1970s, when the introduction of sync-sound reflex cameras meant you could run out with a battery and a small crew and just make something. We wanted Splitsville to honor that spirit; we worked with the mindset that we would strive to create something special without bogging it down with too many tools or people. We wanted the look to come across as intentional yet raw.

    Following Ashley’s (Adria Arjona, center right) desire to divorce Carey (Kyle Marvin, center left), the couple and their friends, Paul (Covino, left) and Julie (Dakota Johnson, right), become entangled in a relationship dynamic with bizarre complications..

    Mike understands how to highlight the absurdity of the human experience, and to that end, Splitsville moves from moments of minimalism and simplicity to extreme maximalism. We sought to constantly upend our relationship with the audience so they’d never be completely comfortable with the story we’re telling. The extended fight scene, which places the viewer right inside a brawl between Carey (Kyle Marvin) and Paul (Mike) after the former tells the latter he has slept with his wife, Julie (Dakota Johnson), falls firmly on the maximal side of this tonal spectrum.

    Broken Home: Choosing the Fight Scene’s Location

    For our fight-scene location, we chose a modernist lake house that best represented the type of second home we thought Paul’s character would have — something beautiful that felt connected to the water and nature, but still felt like a bold, modern statement of wealth and abundance. We then discussed what within the environment might be possible to break, and which spaces would be most fun to move through. We considered how the scene could start out simply as a moment of believable dialogue; then move into a wrestling match; and then have it devolve into a fight for the characters’ lives that would include breaking pottery and glasses, smashing tables, bodies being thrown down stairs, a fish tank blowing up, and finally, the characters crashing through a window into a swimming pool, all of which was written specifically in the script.

    Paul turns a household item into a deadly weapon during a frenetic brawl with Carey when the former learns that the latter has slept with his wife.

    Our production designer, Stephen Phelps, then helped build furniture pieces and windows for our actors to break. Kyle and Mike worked with stunt coordinator Tyler Hall on the scene every night after prep. At first, their extreme devotion boggled my mind, but it was clear they understood that this early scene would set the tone for the rest of the film.

    Doubling Down on No Stunt Doubles

    Kyle and Mike didn’t have stunt doubles for any part of the sequence. This was a point of pride for them. Early on, I told them the only way the scene would work would be with doubles, and that I didn’t think they would go at each other hard enough, but subconsciously, I think I might have been challenging them! At times, it felt like the three of us were all daring each other to grab the electric fence. I told them they’d have to commit 100 percent or it wouldn’t work, and to their credit, they did it. It’s also true that if your actors can perform something like this themselves, the results look better because you’re not hiding physical actions either with the camera or in the edit. I always push to do things practically even if it means rethinking how we shoot a scene, and here, we leaned into what’s happening in the moment onscreen.

    On location, Newport-Berra, confers with Covino and Marvin before shooting portions of the film’s fight scene, which the actors performed entirely without the use of stunt doubles.

    Camera Techniques and Oners

    We aimed to approach every moment within the sequence as one shot and managed to achieve this in capturing the portion of the fight that takes place in the downstairs area of the house. For the first part of this shot, our Steadicam operator, Andre Perron, rested the Steadicam on an apple box so the shot would feel more locked off; at this point, the shot has a feeling of tension, but it’s also humorous. From there, the confrontation between Carey and Paul slowly escalates. Once the fight is fully underway, the two men fly into the study; at that moment, Andre lifted the Steadicam off the apple box and moved with them into this new room. Following this portion of the fight, Carey and Paul end up back in the living room, then move into the kitchen, then onto the stairwell, with the action in each room covered via the same Steadicam move.

    Also Read: Adam Newport-Berra on Crafting “The Oner” for The Studio

    I love oners; if anything, my work over the last couple of years has shown that shooting them is my dream scenario. But because Kyle and Mike performed their own stunts, and because Splitsville is a comedy about humanity — not an action movie — I also felt that some additional coverage would help the scene, even if it was just one punctuated move that sells the impression of a hit landing harder or a line landing funnier. So, we peppered in these little moments throughout. We shot a reverse on Paul for the beginning of the scene, but chose to remain wide, to keep our distance. This allows the viewer to observe that Paul is reacting, but not completely read into how he feels. We also captured some more extreme angles of the beginning of the wrestling — with one camera on the floor when the characters topple to the ground, to help sell the impact and signal a turning point in the fight; and a top shot of some of their wrestling maneuvers, to help better show their faces and play up the comedy of their lines. For the upstairs portion of the shoot, we added an underwater shot in the bathtub, to reveal Carey’s face as Paul tries to drown him in the tub. We also added close ups here and there for reactions, dialogue, or reveals, like when we see that Carey is missing his eyebrows.

    The filmmakers prepare to shoot a stretch of the fight’s action that takes Paul and Carey outside after they crash through an upstairs window of Paul’s house.

    Choosing — and Shattering — Glass

    For the majority of the fight sequence, we used a Panavision Ultra Speed “Z” MKII series 24mm prime lens. (This lens, paired with Arri’s Arricam LT, our main camera, was occasionally exchanged with other glass in Panavision’s Ultra Speed and “Z” series.) The 24mm felt most natural and honest for the material — it’s wide but not distorted, the camera moves feel dynamic, and it proved versatile in finding wide or tight frames in the sequence seamlessly.

    Our real set pieces — where things really got challenging — came when the fight moves upstairs. During this part, Carey and Paul move into Paul’s son’s room and Paul ends up breaking his son’s massive fish tank by throwing a bowling ball at it. We needed a tank that would be big enough to make an impression on the viewer, but every gallon of water weighs 8 pounds, and our tank held about 60 gallons that would eventually be spilled out. The house we shot in was brand new, and the owners were, understandably, worried. So, our art department designed and built a reservoir that looked like the floor of the room but was covered by carpet; the reservoir weighed about 3,000 pounds and held about 250 gallons, which allowed us to catch all of that water to prevent it from seeping into the floorboards.

    On top of all that, we only had one take to shoot the upstairs material. We had special effects supervisor David Loveday remotely controlling a detonator that broke the fish-tank glass, which had to be perfectly timed with the throwing of the bowling ball. We wanted to capture this moment in camera, and although we did shoot coverage, we took care to avoid cheap cutaways. We needed to see the aftermath of the broken glass and water everywhere with the camera rolling. This was one of the few times we decided to have two cameras rolling to make sure we got the shot. All of this was terrifying, but in the end, we pulled it off.

    Out of Window, Under Water

    Another challenging moment to capture is when Carey and Paul break through the upstairs-hallway window and land in the pool outside. The production built a set that replicated the end of the hallway next to the actual window, and we stitched that together with shots in the hallway. We have a POV shot of Carey and Paul rushing through the window and a profile shot, for which we blocked the house with our set piece to capture them as they crash through the window and land on a mat off camera. We used a 35mm “Z” series lens in this shot to compress the background of the environment and ensure the set felt congruent with the geography of the location.

    The jump for Mike and Kyle was about 15 feet down, and Mike tackling Kyle through breakaway glass had them cut up and bloodied. Shooting on film, we couldn’t watch anything back; we had to just pray the film would come back. We also shot the break through the window at high speed on an Arri 435 Xtreme, which made things even riskier. We did one take, which went well enough. After some discussion, we decided there was no reason to risk doing another one, so we moved on to our aquatic work to capture the moments following the characters’ landing in the pool and their continuation of the fight underwater.

    We spent a morning shooting Mike and Kyle beating the hell out of each other underwater, using the 435 Xtreme, which was fitted into a HydroFlex RemoteAquaCam Mk5 housing.

    Shooting underwater — especially on film — is difficult, because you don’t see what you get until you develop the film. Focus marks change with the flat-front attachment, so our 1st AC, Nico Marion, had to be very calculated in his focus-pulling efforts. On a bigger film, one would probably have another unit prepped to do this, but on our more modest budget, this was just an hour of an otherwise jam-packed day, so we really couldn’t afford to miss the shot. We just dove right in, and everyone nailed it.

    I would never pressure an actor to do something they aren’t comfortable with, but a sequence like this one is always better when it’s practical and done as much with the actors as possible. It takes a lot of faith. If the actors are going to risk their safety, they must trust that I can capture that performance and deliver it in a way that makes it all worth it. It goes to show how important the relationships between cinematographers and actors are, and how much we rely on one another for success.

    All images courtesy of Neon.

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  • Heparanase 2 emerges as key protector of blood vessel integrity

    Heparanase 2 emerges as key protector of blood vessel integrity

    An international research team led by MDI Biological Laboratory President Hermann Haller, M.D. and postdoctoral researcher Yannic Becker, Ph.D. has discovered that a little-known molecule, heparanase 2 (Hpa2), plays a critical role in maintaining blood vessels’ integrity.

    Malfunctions in the vasculature are increasingly seen as an underlying driver of a wide array of diseases.

    The findings were published in the peer-reviewed journal, Arteriosclerosis, Thrombosis, and Vascular Biology. They suggest that Hpa2, which occurs naturally in vertebrates and other animals, could be useful in new therapies for vision and chronic kidney diseases, cardiovascular disease and cancer.

    The vasculature’s interior is lined by the endothelium, a single layer of cells that control what passes in and out of the blood stream. Its permeability and structure depend on heparan sulfate proteoglycans – sugar-based molecules that anchor signaling proteins such as vascular endothelial growth factor (VEGF) to the cells.

    The researchers found that Hpa2, until now poorly understood, also binds strongly to heparan sulfate at the same anchor site, and can block growth-factor signaling.

    VEGF is essential for normal tissue growth and repair. But when overactive it can cause leaky blood vessels, contributing to diseases such as diabetic retinopathy and macular degeneration in the eye, and protein loss in the kidney (proteinuria). It can also aid cancer cells’ ability to highjack the vasculature for their own sustenance.

    Working with zebrafish, mouse kidneys and human endothelial cell cultures, the research team showed that when Hpa2 is absent, vessels lose their structural integrity and become abnormally leaky. Introducing manufactured Hpa2 reversed that fragility, restoring normal vascular function.

    Usually most of our blood vessels are pretty tight, but we saw that if we take out heparanase 2, we have an increased flux of molecules and water into the interstitium. This discovery identifies Hpa2 as an essential safeguard for the blood vessel wall.”


    Yannic Becker, Ph.D., study’s first author

    Key findings

    • Hpa2 is conserved across vertebrates and circulates in the bloodstream.
    • Hpa2 competes with VEGF and other growth factors for binding to endothelial cells, dampening overactive growth-factor signaling.
    • Loss of Hpa2 increases vascular permeability and disrupts endothelial structure in zebrafish.
    • Application of recombinant Hpa2 blocks VEGF-induced permeability and restores vascular function in mouse kidneys.

    “Hpa2 shows promising pharmaceutical potential,” said Haller, the article’s senior author. “Current therapies for vascular disease often focus on blocking growth factor signaling, but Hpa2 may offer a more natural mechanism to restore balance without adverse side effects.”

    Funding

    This research was supported by the German Research Foundation (DFG), the Scott MacKenzie Foundation and the U.S. National Institutes of Health Institutional Development Award (IDeA) program (P20GM103423 and P20GM104318).

    Source:

    MDI Biological Laboratory

    Journal reference:

    Becker, Y., et al. (2025). Heparanase 2 Modulates Vascular Permeability via Heparan Sulfate–Dependent Growth Factor Signaling. Arteriosclerosis Thrombosis and Vascular Biology. doi.org/10.1161/atvbaha.125.323060

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  • Our DNA holds the hidden history of human language

    Our DNA holds the hidden history of human language

    Linguists have long known that when cultures collide, languages rub off on one another. We borrow words, swap sounds, and even reshape grammar. But charting those exchanges across centuries and continents is hard when the written record is patchy or nonexistent.

    A new study flips the problem on its head: instead of starting with history books, the researchers read our DNA to reconstruct past human contact – then asked what happened to the languages.

    DNA traces human language history


    A team led by Anna Graff at the University of Zurich pulled together genetic data from more than 4,700 people in 558 populations. They paired this with two of the world’s largest linguistic databases, which catalogue everything from word order to consonant inventories across thousands of languages.

    Genetic “admixture” – the telltale signature of populations mixing – stands in for a reliable, globally comparable record of contact. With that proxy in hand, the team could identify more than 125 instances where groups clearly met and mingled, even if historians never wrote the encounters down.

    What they saw was unambiguous: when people mix, their languages tend to move closer together. Unrelated languages spoken by populations with genetic contact were four to nine percent more likely to share features than expected.

    That might sound modest, but across entire grammars and sound systems, it’s a strong, consistent nudge toward similarity.

    One surprise was how steady that effect proved to be. Whether the contact was vast and recent – say, colonial movements between continents – or ancient and regional, like Neolithic migrations within Eurasia, the degree of linguistic convergence was strikingly similar.

    “No matter where in the world populations come into contact, their languages become more alike to remarkably consistent extents,” said senior author Chiara Barbieri, now at the University of Cagliari.

    That consistency cuts against a common assumption that only intense, prolonged encounters reshape grammar and sound systems, or that small-scale neighborly contact leaves barely a trace.

    The genetic lens suggests languages are sensitive instruments, registering social touchpoints across the full spectrum – from trade and intermarriage to conquest and diaspora.

    Not all grammar is transferable

    Of course, not every part of a language is equally malleable. Some features seem to travel more readily. Word order patterns and certain consonant sounds were more likely to converge than deeper layers of morphology or prosody.

    But here, too, the study counsels caution. The researchers didn’t find a one-size-fits-all rulebook that says, for example, “Nouns move; verb endings don’t.”

    That challenges decades of “borrowability hierarchies” that rank which features can be shared across languages. Instead, the authors argue, social dynamics – prestige, power, identity, and the practicalities of multilingual life – can override structural inertia.

    If a community prizes a dominant group’s speech, it may adopt conspicuous elements quickly; if it resists assimilation, the most “borrowable” features might barely budge.

    You can see the everyday version of this push and pull in familiar loanwords. English picked up “sausage” from French after the Norman Conquest; centuries later, French borrowed “sandwich” from English.

    Vocabulary swaps like these are the visible tip. Beneath the surface, the new study shows, subtler shifts in sound and syntax can ripple outward whenever people share space and stories.

    The team even found the mirror image of borrowing: divergence on purpose. In some places, features became less alike after contact, not more.

    That happens when communities lean into linguistic differences to mark who they are – tightening vowel systems, restoring older word orders, or reinforcing local pronunciations as a badge of identity. In other words, contact doesn’t always melt boundaries; sometimes it sharpens them.

    This duality – convergence alongside intentional distancing – is central to how languages evolve. It helps explain why some neighboring tongues grow steadily more alike, while others cling to distinctiveness despite centuries of cohabitation.

    DNA tells story of language

    Methodologically, the study’s move is elegant. Historical documents and oral traditions can be rich but patchy, and for many regions and eras they simply don’t exist.

    Genes keep a different kind of ledger. When populations intermix, they leave a durable statistical imprint that persists for thousands of years.

    By aligning those genetic signals with language structures, the authors could quantify contact and its linguistic consequences on a global canvas – from Amazonia and the Sahel to the Pacific and the Arctic.

    The approach also helps disentangle coincidence from contact. Two unrelated languages might independently develop similar features for internal reasons. But when that similarity lines up with clear genetic admixture between the speakers, the balance of probability shifts toward historical interaction.

    Languages evolve in real time

    Beyond satisfying our curiosity about how English, Hausa, Quechua, or Hmong came to be what they are, the findings carry a warning for the present. Contact has always been part of human life, but the pace and scale are accelerating.

    Globalization, urbanization, climate-driven displacement, and land-use change are bringing communities together – and pushing others apart – in new ways. As that churn intensifies, we should expect languages to converge more in some respects and to splinter or vanish in others.

    It also reframes the stakes of language loss. We often focus on shrinking vocabularies and disappearing oral literatures.

    This study suggests that deeper, structural layers – sound patterns, grammatical architectures, the hidden wiring of a language – can erode under sustained contact, even when a language survives on the surface.

    Protecting linguistic diversity, then, isn’t only about counting how many languages remain; it’s about preserving the full range of their internal variety.

    DNA and language share histories

    The research tells a familiar human story with fresh evidence. When people meet – through trade or conquest, migration or marriage – we share more than DNA. We pass around technologies, beliefs, recipes, and ways of speaking.

    Some of those exchanges are voluntary, others are imposed; some knit communities together, others spark efforts to stand apart. Our languages, like our DNA, carry the scars and gifts of those encounters.

    By treating genes as a time machine, this study gives linguistics a new global baseline. It doesn’t replace fieldwork, historical scholarship, or typological theory.

    It makes them sharper, pointing to where contact likely mattered and how deeply. And it leaves us with a clear takeaway for the century ahead: as our lives intertwine ever more tightly, the sounds and structures we use to make meaning will change with them.

    The study is published in the journal Science Advances.

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  • Why trans art matters more than ever: ‘It reflects how people live and love’ | Art

    Why trans art matters more than ever: ‘It reflects how people live and love’ | Art

    Part of the magic of portraiture is how it renders so much of the human experience accessible to us, things we might never see otherwise. This has been very much on Black artist Amy Sherald’s mind. When I spoke to her in advance of the debut of her exhibition American Sublime, she told me that Black representation was foundational to her practice: “I developed this idea that, when I look at art history, for the most part I don’t see portraits of people that look like me. So it started there.”

    That exhibition’s curator, Sarah Roberts, also spoke about Sherald’s passion for representing the LGBTQ+ community: “Amy has thought a lot about her role as an artist and the need for representation, and she has long been a champion of LGBTQ+ rights. This work is thinking about who gets depicted as being American.”

    It was no surprise, then, that Sherald would have a very strong reaction when the Smithsonian attempted to censor Trans Forming Liberty, a portrait that she made of the Black trans woman Arewà Basit, out of American Sublime in advance of its arrival there. As Sherald told the New Yorker: “Trans Forming Liberty challenges who we allow to embody our national symbols – and who we erase. It demands a fuller vision of freedom, one that includes the dignity of all bodies, all identities … This portrait is a confrontation with that truth.”

    More than just censoring Trans Forming Liberty from American Sublime to appease the Trump administration, the Smithsonian added insult to injury when it suggested that Sherald replace her artwork with a video of cisgender people debating whether or not trans people deserved inclusion in American society. The artist lost no time in responding to these actions by pulling her show from the Smithsonian.

    Amy Sherald’s Trans Forming Liberty on display. Photograph: Matthew Millman/Matthew Millman Photography

    The skirmish over Sherald’s piece highlights the importance of trans representation in the artwork that hangs in our museums and galleries – a 2022 Pew poll found that less than half of Americans believed that they had ever met a trans person, meaning that seeing representation such as Sherald’s might add a dose of empathy and connection to a community that is in need of compassion from cisgender Americans. At the time when the trans community is being demonized with the fervor of a moral panic, it is no exaggeration to say that such encounters are transformational.

    The Bay Area trans artist Éamon McGivern has made trans portraiture central to his artistic practice. His collection, Still Lives, a Trans Portrait Project, was recently shown in the Tenderloin Museum in San Francisco as a tribute to his connection with the trans community.

    McGivern was appalled, although not surprised, at the idea that trans people are now being erased from museums with strong ties to the federal government. “We’re at a point where you can’t show a picture of a trans person at a federally funded institution and that’s bad, that’s fascism,” he said. “If cis artists are being asked to edit, what does that mean for queer and trans people?

    He awarded Sherald points for understanding the importance of representing trans people in her art. “Since Sherald’s an artist of color, I’m sure she has to think these issues through more than the average person. The fact that she cares enough about trans people enough to include them in her body of work means that she gets it.”

    Éamon McGivern – Ray and Sathya, 2022. Photograph: Éamon McGivern

    While showing his work, McGivern has frequently seen cisgender people have to wrestle with their preconceived stereotypes around who trans people actually are. “The response I get from cisgender people is that they didn’t know trans people looked like that,” he said. “And that really opened my eyes, where I’m like: ‘Wow, people have such a narrow view.’ That we can just be normal people living normal lives.”

    McGivern sees trans portraiture as far more than just a way of acquainting cisgender viewers with the trans experience. He shared that his series of portraits of trans people came out of his own experience of isolation after undergoing gender-affirming surgery: “I lost my housing during recovery from top surgery,” he said. “I looked around, and I realized that I didn’t have any capital T trans people in my life. I needed trans people around me who got it.”

    Painting portraits of trans people became a lifeline at the very time he needed it: his art helped him build exactly the community he was in search of. “I started reaching out to people who I thought were cool hot trans people. I wanted to show portraits of people who were not alone and in community. Reaching out to people who seemed to have that in their lives, showing that in my art was subconsciously a way of getting that for myself.”

    Like McGivern, Atlanta artist Sean La’Mont began creating trans portraits as a way of being in community. She recalled that in 1997 she began to frequent drag clubs and was astonished by the beauty of the trans women who danced there. “I thought: ‘Wow, these are amazing people!’ and it was that curiosity that started me drawing them.”

    Artwork by Sean La’Mont. Photograph: Courtesy of the artist

    La’Mont’s years of drawing the trans community have brought her into contact with some astonishing trans people, including surgeon Dr Marci Bowers, who is considered one of the top vaginoplasty surgeons in the world. La’Mont recalled that at a trans health symposium in Atlanta she got the chance to come face to face with a personal hero – and draw her portrait.

    “I was invited to do a show with the Trans Symposium, and Bowers happened to be the guest speaker that year,” she recalled. “The event organizers asked me to draw her, and then they presented it to her at the event. She was so gracious about it. She’s been an idol, she’s pretty incredible.”

    For La’Mont, it’s the love of her community that has kept her inspired to draw portraits of trans people for decades now, something she’s eager to share with the cisgender population. “Art reflects how people live and love, and some of the greatest pieces are the ones that show how we live and love. I see their reaction, it’s like: ‘Oh my God, that’s beautiful.’”

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  • Massage, heat, and cold therapy in feline rehabilitation

    Massage, heat, and cold therapy in feline rehabilitation

    Photo: steevy84/Adobe Stock

    Physical therapy and rehabilitation tailored specifically for cats can make a significant difference in the wellbeing of these felines. Cats recovering from surgery, as well as those who have osteoarthritis, are overweight, or are healing from non-surgical injuries may see improved mobility, faster recovery, and an overall improved quality of life, according to Michael H. Jaffe, DVM, MS, CCRP, DACVS, an associate professor of small animal surgery at Mississippi State University College of Veterinary Medicine, who led a Fetch dvm360 Conference lecture on the topic this past weekend in Kansas City, Missouri.1

    Other benefits of rehabilitation therapy include1:

    • Promoting early weight-bearing and return to function
    • Supporting weight loss
    • Improving proprioception and movement
    • Promoting tissue healing
    • Providing positive psychological effects
    • Increasing strength and endurance
    • Improving flexibility
    • Reducing pain, inflammation, and swelling
    • Offering a non-invasive approach
    • Carrying minimal risk of complications
    • Preventing compensatory injuries
    • Engaging owners in their pet’s care

    “I always say that with surgery, we put the pieces together, but physical therapy and rehab gets the parts moving again. And I think there’s a lot of truth to that,” said Jaffe during his presentation.1

    Massage therapy

    Pet owners and practice owners who may not have specialized rehabilitation equipment can perform massage therapy on cats, explained Jaffe. This type of therapy promotes blood flow to the muscles, improves connective tissue strength and tendon elasticity, reduces some muscle spasms, and lowers stress and anxiety. According to Jaffe, massage therapy is also beneficial for breaking down adhesions.

    “As far as lymphatic flow, that’s important, because any edema that may form in the tissue, or certainly distal to the tissue, can be mobilized pretty quickly in terms of promoting that blood flow and improving the lymphatics to help drain some of that edema that’s forming in the interstitial space,” he added.

    In patients that have undergone surgery, Jaffe explained this therapy should be started within the first 24 to 48 hours after the procedure. Some patients may even receive massage therapy prior to undergoing more intensive rehabilitation protocols, noted Jaffe. Additionally, clients can be taught to perform massage therapy on their pets at home.

    When it comes to the massage technique, Jaffe said he likes to isolate one joint at a time rather than doing a bicycle movement or the “accordion movement where you grab the foot and you pull the leg forward and back and forward and back.

    “I really don’t like to work on more than one joint at a time because with activities like the bicycle motion or the accordion motion, you are working all of the joints at one time, and not every joint is going to be capable of the same mobility as others,” Jaffe emphasized. “To try to prevent injuries, I really think it’s best to work each individual joint by itself: hold the stretch for just a second or 2 and then…release it so that we don’t injure the patient.”

    Heat therapy

    As Jaffe explained, hot compresses cause vasodilation, promoting blood flow to tissues and increasing their metabolic rate. Heat therapy also increases the release of histamines, bradykinins, and prostaglandins, which may help lower inflammation in the tissue that is being warmed.

    “This does also have the benefit of improving flexibility of fibrous tissue and so [for] joint capsule that may be a little bit contracted, it’s going to loosen things up a little bit,” said Jaffe.

    Patients with chronic diseases, such as osteoarthritis or back pain will benefit from this form of therapy. According to Jaffe, heat therapy also improves lymphatic flow and can help decrease swelling and edema in tissue. Jaffe suggests doing a warm compress beginning at approximately 24 or 48 to 72 hours after a surgical procedure.

    “Initially, we’re going to use our cold compresses to try to reduce some of the pain and inflammation at the surgery site following surgery. We’ll certainly do cold compresses on our incision, but [for] the muscles that we’ve manipulated and have moved around and that have developed injuries, we’re going to want to do warm compresses on those to try to improve that blood flow and promote healing,” explained Jaffe.

    “I often use [heat therapy] as part of our warm up prior to any massage or passive range of motion or other exercises,” said Jaffe. “I like to use it to help decrease some of the muscle tightness prior to when we do our stretches and help decrease any muscle spasms as we work our muscles and take them through range of motion.”

    Jaffe warns against using heat therapy for tumors because the blood flow to the tissue could promote metastasis. Other contraindications include open wounds, patients with severe cardiac insufficiency, and acute inflammation—for which cold compresses should be used in the first 48 to 72 hours post surgery. Additionally, veterinary professionals and pet parents at home should be careful when using hot compresses in areas with decreased or absent sensation, as well as with making sure the temperature is not too hot that it can burn the pet.

    Cold therapy

    Unlike heat therapy, cold therapy causes vasoconstriction, decreasing edema formation and helping to lower inflammation and hematomas that may form from an acute injury, said Jaffe.

    “A lot of times when we’re putting a pet through a fairly vigorous workout with our rehab protocols, we’re going to ice them down afterwards,” explained Jaffe. “We’re going to use our cold compresses to decrease any pain or muscle spasms or muscle injury that may have occurred during our rehab session.”

    Ice packs can be used for cold therapy, but caution should be taken not to put the packs directly on the cat’s skin. Instead, the ice packs should be wrapped in a towel to prevent cold shock or injury to the patient’s skin. Each session, Jaffe explained, should last no longer than 10 to 15 minutes. However, sessions can be repeated approximately every 4 hours as needed.

    References

    1. Jaffe MH. Feline physical therapy and rehabilitation. Presented at: Fetch dvm360 Conference; August 25-26, 2025; Kansas City, Missouri.

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  • Digging into plant roots with DNA – no shovels required

    Digging into plant roots with DNA – no shovels required

    We stroll past wheat, clover, and grass and see only the green half of the story. The other half – the roots – do the heavy lifting: anchoring plants, pulling up water and nutrients, and locking away carbon in the soil.

    Yet because roots are hidden, scientists have spent decades using muddy, labor-intensive methods to guess their size and spread, often missing the finest, most active threads. According to a team of researchers at Aarhus University, that guesswork can finally stop.

    A high-tech root census


    “It’s a bit like studying marine ecosystems without ever being able to dive,” said senior author Henrik Brinch-Pedersen, a professor in the Department of Agroecology.

    Until now, the standard approach was to carve out big blocks of soil, wash away the dirt, sort and dry what remained, and weigh the roots. It’s slow, destructive, and misses the fine roots that absorb nutrients and release carbon to the soil.

    The new approach swaps spades for droplet digital PCR (ddPCR), a DNA technology that partitions a teaspoon of soil into tens of thousands of microscopic droplets. Each droplet then answers a yes/no question: Does it contain plant DNA with a specific genetic signature?

    The team uses a marker called ITS2 – think of it as a barcode that differs among species – so a single run can reveal not just that roots are present, but whose roots they are. Crucially, it also shows how much underground biomass each species contributes.

    “It’s a bit like giving the soil a DNA test,” Brinch-Pedersen said. “We can suddenly see the hidden distribution of species and biomass without digging up the whole field.”

    Mapping roots with precision

    Because ddPCR counts DNA molecules across thousands of droplets, it can quantify roots that would otherwise be pulverized or rinsed away.

    That makes it possible to map root communities at high resolution in living fields, pastures, and mixed-species grasslands and to repeat measurements over time without disturbing the site.

    The payoff spans several fronts. For climate research, it lets scientists measure how much carbon different crops actually push belowground – data that’s been frustratingly hard to pin down but is essential for credible climate accounting in agriculture.

    For plant breeding, the digital DNA method creates a path to select varieties that invest more in roots without sacrificing grain or forage aboveground.

    And for biodiversity science, the technology finally illuminates the underground dynamics in species mixes – who’s competing, who’s complementing – insights that were “almost impossible before,” Brinch-Pedersen noted.

    Roots matter for the climate

    We tend to picture wind turbines and EVs when we think of climate solutions, but roots are a vast, quiet carbon pump.

    As plants photosynthesize, some of the captured carbon flows belowground into roots and the surrounding soil. Depending on the crop, soil type, and management, a fraction of that carbon can persist for decades or even centuries.

    Farmers and policymakers talk about “soil carbon sequestration,” but without precise measurement tools it’s been hard to document gains in ways that stand up to scrutiny. A rapid, species-resolved root assay changes that equation.

    DNA test in soil

    In practice, researchers collect small soil cores, extract DNA, and run ddPCR with species-specific probes keyed to the ITS2 barcode. The number of positive droplets scales with root biomass for that species in that sample.

    Because the test targets DNA directly in soil, it captures fine roots and root fragments as well as thicker roots that are tough to wash and weigh.

    There are, however, limits. Close relatives can be tricky to tell apart when their barcodes are nearly identical – ryegrass and Italian ryegrass hybrids, for instance, can blur the signal.

    And the method recognizes only what it’s trained to find. Researchers must validate a probe for each species, so expanding the “DNA library” is both the hurdle and the goal.

    “For us, the most important thing is that we have shown it can be done,” Brinch-Pedersen said. “Our vision is to expand the library so we can measure many more species directly in soil samples.”

    Rapid answers from soil

    Speed is the other advantage. Traditional root studies hinge on days to weeks of field and lab work per site. The ddPCR method turns around results in hours, making it practical to scale from a few experimental plots to entire farms, seasons, and regions.

    That opens the door to experiments that were previously unrealistic. Researchers can compare cover crops for their belowground carbon contributions across soil types.

    They can track how drought shifts root allocation among species in a pasture. They can also screen hundreds of breeding lines for deeper, denser root systems.

    Plants that work smarter

    Brinch-Pedersen sees a straight line from measurement to design. If breeders can quantify underground investment as easily as they count kernels or measure protein, they can begin to select for crops that are not only high-yielding but also high-sequestering. These are plants that do more of the climate work for us.

    The same logic applies to mixtures. With species-level root data, agronomists can compose plant communities that pack more carbon belowground while maintaining forage or grain output above.

    The bigger picture is simple: half a plant lives out of sight, and that half shapes soil health, farm resilience, and the climate. With a “DNA test for dirt,” researchers can finally watch that hidden half at work – no shovels required.

    The study is published in the journal Plant Physiology.

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  • Gut disorders may foretell Alzheimer’s, Parkinson’s disease

    Gut disorders may foretell Alzheimer’s, Parkinson’s disease

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    Chronic gut problems may predict Alzheimer’s, Parkinson’s disease risk, a new study suggests. Image credit: Halfpoint Images/Getty Images
    • Currently, neurodegenerative conditions, such as Parkinson’s and Alzheimer’s diseases, are challenging to preempt.
    • A large-scale, innovative new study investigates how hormonal, dietary, metabolic, and digestive issues may help predict these conditions years before they begin.
    • The study identifies several conditions that are associated with an increased risk of Alzheimer’s and Parkinson’s.
    • Importantly, the findings also hint at ways to help reduce the risk of developing these disorders.

    A new study, published in Science Advances, investigates links between 155 health conditions and the future risk of developing Alzheimer’s and Parkinson’s.

    The scientists identified several relatively easy-to-treat conditions that are linked to the later development of neurodegenerative conditions, years before symptoms begin.

    Additionally, the study identifies that the timing of each condition affects the size of the risk increase.

    There are many versions of neurodegenerative diseases — conditions marked by the degradation of the brain — but Parkinson’s and Alzheimer’s are the most common.

    Despite decades of focus and millions of dollars worth of research, they remain steadfastly difficult to predict and treat.

    Once these conditions begin, some drugs can slow progress for some patients; however, there is no cure, and no surefire way to know who will develop them.

    Medical News Today spoke with Lucy McCann, MBChB, MSc, ANutr, a medical doctor and registered nutritonist, about the importance of this study.

    “Alzheimer’s and Parkinson’s disease are among the most common neurodegenerative disorders in the world. With an aging population, preventing and managing these conditions is becoming a public health priority,” McCann, who was not involved in the research, explained.

    Research has also shown that the processes involved in these diseases begin decades before symptoms appear. Because of this, scientists are focusing on identifying any clues from middle age that could provide opportunities to stop disease progression in its tracks.

    In recent years, scientists have focused on the potential role of the so-called gut-brain axis in neurodegenerative diseases. In short, the gut-brain axis is two-way communication between the gut and the brain.

    The communication has many modalities, including:

    • hormonal, for example through gut peptides
    • nervous, e.g. the vagus nerve
    • immune, e.g. cytokines.

    These messaging pathways and more, as the authors of the new study explain, facilitate “constant interactions between the brain, digestive, endocrine, metabolic systems and nutritional status.”

    The nervous system of the gut, known as the enteric nervous system, is the second largest collection of neurons outside of the brain.

    At first glance, it is difficult to understand why the brain and gut are so intimately linked. However, when we remember that food is essential for our survival, and that we cannot find it without our brain, the connections begin to make sense.

    Alongside conditions involving the gut-brain axis, scientists have also identified links between hormonal and metabolic conditions and an individual’s risk of developing a neurodegenerative condition.

    For instance, the authors of the recent study explain that more severe cases of diabetes and imbalances in thyroid hormones — both hypo- and hyperthyroidism — are associated with Parkinson’s disease. Similarly, type 2 diabetes is a well-known risk factor for Alzheimer’s disease.

    At the same time, some nutrient deficiencies seem to play a part, including vitamin D, which is often present in lower levels in those with Alzheimer’s and Parkinson’s. Over the years, it has also become clear that some digestive disorders appear before the symptoms of Parkinson’s and are associated with increased dementia risk.

    While these findings offer some insight, many questions remain. The latest study sets out to bring some more clarity to these varied and overlapping associations.

    In the latest study, the scientists investigated associations between Parkinson’s, Alzheimer’s, and 155 disorders associated with:

    • the endocrine system
    • nutritional factors
    • the metabolic system
    • the digestive system.

    Interestingly, the scientists designed their analysis to examine how the timing of these conditions influenced future risk by stratifying the data into:

    • 1–5 years
    • 5–10 years
    • and 10–15 years before an Alzheimer’s or Parkinson’s diagnosis.

    The researchers found that 14 diagnoses were associated with an increased risk of Alzheimer’s disease, including:

    Conditions significantly associated with a later diagnosis of Parkinson’s disease included:

    • dyspepsia — chronic indigestion
    • diabetes, both type 1 and type 2
    • other disorders of pancreatic internal secretion — these disorders include diabetes, but also hypoglycemia (low blood sugar) and increased glucagon secretion
    • functional intestinal disorders
    • deficiency of B vitamins.

    MNT spoke to David Perlmutter, MD, a board-certified neurologist and Fellow of the American College of Nutrition, about the study findings.

    “The most striking aspect is how clearly the study links systemic disorders, particularly those tied to the gut-brain axis, with neurodegeneration risk years before diagnosis,” said Perlmutter, who was not involved in this study.

    “This reinforces the view that Alzheimer’s and Parkinson’s are not isolated brain diseases but the end stage of a decades-long, body-wide process,” he suggested.

    The study authors investigated how the timing of these conditions influenced future risk of developing a neurodegenerative condition.

    For instance, the link between type 2 diabetes and Alzheimer’s was strongest when diagnosed 10–15 years earlier compared with later diagnosis. This, the researchers suggest, may be due to “cumulative metabolic effects.”

    By contrasy, a type 1 diabetes diagnosis increased the risk of Alzheimer’s to a similar extent across all three time windows.

    For Parkinson’s, type 1 diabetes was most strongly associated when diagnosed 5 to 10 years before the onset of Parkinson’s, whereas type 2 diabetes had a similar risk across all three time windows.

    In general, when looking at all conditions together, the links with neurodegenerative conditions were strongest when diagnosed 10–15 years earlier.

    The authors wrote that “[t]hese findings underscore the importance of diagnosis timing in neurodegenerative risk modeling and suggest that both early-life exposures and recent comorbidities contribute to disease vulnerability.”

    This study confirms associations between health conditions and the risk of developing Alzheimer’s and Parkinson’s. It also adds extra depth to our understanding.

    The authors hope that by drilling down into these links, doctors may be able to focus on treatments and potentially reduce or even prevent the onset of these challenging-to-manage neurodegenerative conditions.

    We asked Perlmutter how the results might help reshape prevention strategies. He explained that it will put a “much greater emphasis on maintaining metabolic, endocrine, and gut health as a means of protecting the brain.”

    “Rather than waiting for symptoms to emerge, clinicians and individuals could use systemic health markers, such as thyroid status, blood sugar control, vitamin levels, and digestive health, as early warning signs of elevated risk.”

    “What’s clear from studies like this,” McCann also explained, “is that it’s not just genes that dictate our brain health — other factors such as nutrition, metabolism, and the gut-brain connection play a crucial role.”

    “Combining these features could help us predict and spot conditions such as Alzheimer’s and Parkinson’s earlier than ever before,” she added.

    As is often the case with scientific research, this recent study also leaves some unanswered questions.

    For instance, “It is not yet clear whether gut and metabolic disorders directly cause neurodegeneration or whether they reflect shared underlying processes such as mitochondrial dysfunction and chronic inflammation,” Perlmutter told MNT.

    “These mechanisms are central to the shift of microglial cells to a pro-inflammatory state, which is an emerging mechanism in neurodegenerative conditions,” he noted.

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  • Japan names 80-strong host nation team for WCH Tokyo 25 | News | Tokyo 25

    Japan names 80-strong host nation team for WCH Tokyo 25 | News | Tokyo 25

    Defending champion Haruka Kitaguchi, two-time world champion Toshikazu Yamanishi and national record-holder Rachid Muratake are among the 80 athletes named on Japan’s team for the home World Athletics Championships Tokyo 25, taking place from 13-21 September.

    Kitaguchi, who won the Olympic title in Paris after claiming her world gold in Budapest, will defend her javelin title, while world record-holder Yamanishi will look to regain a world 20km race walk title he won in 2019 and retained in 2022.

    Muratake became the first Japanese athlete to break 13 seconds in the 110m hurdles and currently sits second on this season’s top list. His national record of 12.92 puts him joint 11th on the world all-time list.

    The team also includes Nozomi Tanaka in the 1500m and 5000m, Ryuji Miura in the 3000m steeplechase and Yuto Seko in the high jump.

    Japanese team for Tokyo

    Women
    200m: Abigeirufuka Ido
    400m: Nanako Matsumoto
    800m: Rin Kubo
    1500m: Tomoka Kimura, Nozomi Tanaka
    5000m: Ririka Hironaka, Nozomi Tanaka, Yuma Yamamoto
    10,000m: Ririka Hironaka, Mikuni Yada
    100m hurdles: Mako Fukube, Hitomi Nakajima, Yumi Tanaka
    3000m steeplechase: Miu Saito
    High jump: Nagisa Takahashi
    Pole vault: Misaki Morota
    Long jump: Sumire Hata
    Triple jump: Mariko Morimoto, Maoko Takashima
    Discus: Nanaka Kori
    Javelin: Haruka Kitaguchi, Sae Takemoto, Momone Ueda
    Marathon: Yuka Ando, Kana Kobayashi, Sayaka Sato
    20km race walk: Nanako Fujii, Kumiko Okada, Ayane Yanai
    35km race walk: Masumi Fuchise, Yukiko Umeno, Maika Yagi

    Men
    100m: Yoshihide Kiryu, Yuhi Mori, Abdul Hakim Sani Brown
    200m: Shota Iizuka, Soshi Mizukubo, Towa Uzawa
    400m: Yuki Joseph Nakajima, Fuga Sato
    800m: Ko Ochiai
    1500m: Kazuto Iizawa
    5000m: Nagiya Mori
    10,000m: Jun Kasai, Mebuki Suzuki
    110m hurdles: Shunsuke Izumiya, Rachid Muratake, Shusei Nomoto
    400m hurdles: Shunta Inoue, Daiki Ogawa, Ken Toyoda
    3000m steeplechase: Ryuji Miura
    High jump: Ryoichi Akamatsu, Yuto Seko, Tomohiro Shinno
    Long jump: Yuki Hashioka, Riku Ito, Hibiki Tsuha
    Discus: Masateru Yugami
    Hammer: Shota Fukuda
    Javelin: Roderick Genki Dean, Gen Naganuma, Yuta Sakiyama
    Marathon: Ryota Kondo, Naoki Koyama, Yuya Yoshida
    20km race walk: Satoshi Maruo, Toshikazu Yamanishi, Kento Yoshikawa
    35km race walk: Hayato Katsuki, Masatora Kawano, Satoshi Maruo
    4x100m: Naoki Inoue, Yoshihide Kiryu, Yuki Koike, Yuhi Mori, Naoki Okami, Abdul Hakim Sani Brown
    4x400m: Kenki Imaizumi, Yuki Joseph Nakajima, Fuga Sato, Kentaro Sato, Sho Tanabe, Takuho Yoshizu

    Mixed
    4x400m: Arie Aoki, Abigeirufuka Ido, Shinya Hayashi, Nanako Matsumoto, Sorato Shimizu, Hiroki Yanagita

     

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