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  • Smart Nanomaterial Aids in Cancer Diagnosis and Treatment

    Smart Nanomaterial Aids in Cancer Diagnosis and Treatment


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    The Korea Research Institute of Standards and Science (KRISS) has successfully developed a nanomaterial capable of simultaneously performing cancer diagnosis, treatment, and immune response induction. Compared to conventional nanomaterials that only perform one function, this new material significantly enhances treatment efficiency and is expected to serve as a next-generation cancer therapy platform utilizing nanotechnology.

    Currently, cancer treatments primarily include surgery, radiation therapy, and chemotherapy. However, these treatments have significant limitations, as they not only affect cancerous areas but also cause damage to healthy tissues, leading to considerable side effects.

     

    Cancer treatment using nanomaterials has emerged as a next-generation technology that aims to overcome the limitations of conventional treatments. By utilizing the physical and chemical properties of nanomaterials, it is possible to precisely target and deliver drugs to cancer cells and affected areas. Additionally, personalized treatments based on individual genetic profiles are now possible, offering a therapy that significantly reduces side effects while improving effectiveness compared to traditional methods.

     

    The KRISS Nanobio Measurement Group has developed a new nanomaterial that not only allows real-time monitoring and treatment of cancerous areas but also activates the immune response system. The nanomaterial developed by the research team is a triple-layer nanodisk (AuFeAuNDs), with iron (Fe) inserted between gold (Au). The design of the nanomaterial, which features iron at the center of a disc-shaped structure, provides superior structural stability compared to traditional spherical materials. Additionally, by applying a magnet near the tumor site, the magnetic properties of the iron allow the nanomaterial to be easily attracted, further enhancing treatment efficiency.

    The nanodisk developed by the research team is equipped with photoacoustic (PA) imaging capabilities, allowing for real-time observation of both the tumor’s location and the drug delivery process. PA is a technique that visualizes the vibrations (ultrasound) generated by heat when light (laser) is directed at the nanodisk. By using this feature, treatment can be performed at the optimal time when the nanomaterial reaches the tumor site, maximizing its effectiveness. In fact, in animal experiments, the research team successfully tracked the accumulation of nanoparticles at the tumor site over time using PA imaging, identifying that the most effective time for treatment is 6 hours after the material is administered.

     

    Furthermore, this nanodisk can perform three different therapeutic mechanisms in an integrated manner, which is expected to treat various types of cancer cells, unlike materials that are limited to single therapies. While conventional nanomaterials used only photothermal therapy (PTT), which involves heating gold particles to eliminate cancer cells, the nanodisk developed by the research team can also perform chemical dynamic therapy (CDT) by utilizing the properties of iron to induce oxidation within the tumor, as well as ferroptosis therapy.

     

    After treatment, the nanodisk also induces immune response substances. The developed nanodisk prompts cancer cells to release danger-associated molecular patterns (DAMPs) when they die, which helps the body recognize the same cancer cells and attack them if they recur. In animal experiments, the research team confirmed that the generation of warning signals through the nanodisk led to an increase in immune cell count by up to three times.

    Dr. Lee Eun Sook stated, “Unlike conventional nanomaterials, which are composed of a single element and perform only one function, the material developed in this study utilizes the combined properties of gold and iron to perform multiple functions.”

    Reference: Lee ES, Choi S, Lee J, et al. Au/Fe/Au trilayer nanodiscs as theranostic agents for magnet-guided photothermal, chemodynamic therapy and ferroptosis with photoacoustic imaging. Chem Eng J. 2025;505:159137. doi: 10.1016/j.cej.2024.159137

    This article has been republished from the following materials. Note: material may have been edited for length and content. For further information, please contact the cited source. Our press release publishing policy can be accessed here.

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  • Autonomous Robotic System Speeds Up Semiconductor Research

    Autonomous Robotic System Speeds Up Semiconductor Research

    Scientists are striving to discover new semiconductor materials that could boost the efficiency of solar cells and other electronics. But the pace of innovation is bottlenecked by the speed at which researchers can manually measure important material properties.

    A fully autonomous robotic system developed by MIT researchers could speed things up.

    Their system utilizes a robotic probe to measure an important electrical property known as photoconductance, which is how electrically responsive a material is to the presence of light.

    The researchers inject materials-science-domain knowledge from human experts into the machine-learning model that guides the robot’s decision making. This enables the robot to identify the best places to contact a material with the probe to gain the most information about its photoconductance, while a specialized planning procedure finds the fastest way to move between contact points.

    During a 24-hour test, the fully autonomous robotic probe took more than 125 unique measurements per hour, with more precision and reliability than other artificial intelligence-based methods.

    By dramatically increasing the speed at which scientists can characterize important properties of new semiconductor materials, this method could spur the development of solar panels that produce more electricity.

    “I find this paper to be incredibly exciting because it provides a pathway for autonomous, contact-based characterization methods. Not every important property of a material can be measured in a contactless way. If you need to make contact with your sample, you want it to be fast and you want to maximize the amount of information that you gain,” says Tonio Buonassisi, professor of mechanical engineering and senior author of a paper on the autonomous system.

    His co-authors include lead author Alexander (Aleks) Siemenn, a graduate student; postdocs Basita Das and Kangyu Ji; and graduate student Fang Sheng. The work appears today in Science Advances.

    Making contact

    Since 2018, researchers in Buonassisi’s laboratory have been working toward a fully autonomous materials discovery laboratory. They’ve recently focused on discovering new perovskites, which are a class of semiconductor materials used in photovoltaics like solar panels.

    In prior work, they developed techniques to rapidly synthesize and print unique combinations of perovskite material. They also designed imaging-based methods to determine some important material properties.

    But photoconductance is most accurately characterized by placing a probe onto the material, shining a light, and measuring the electrical response.

    “To allow our experimental laboratory to operate as quickly and accurately as possible, we had to come up with a solution that would produce the best measurements while minimizing the time it takes to run the whole procedure,” says Siemenn.

    Doing so required the integration of machine learning, robotics, and material science into one autonomous system.

    To begin, the robotic system uses its onboard camera to take an image of a slide with perovskite material printed on it.

    Then it uses computer vision to cut that image into segments, which are fed into a neural network model that has been specially designed to incorporate domain expertise from chemists and materials scientists.

    “These robots can improve the repeatability and precision of our operations, but it is important to still have a human in the loop. If we don’t have a good way to implement the rich knowledge from these chemical experts into our robots, we are not going to be able to discover new materials,” Siemenn adds.

    The model uses this domain knowledge to determine the optimal points for the probe to contact based on the shape of the sample and its material composition. These contact points are fed into a path planner that finds the most efficient way for the probe to reach all points.

    The adaptability of this machine-learning approach is especially important because the printed samples have unique shapes, from circular drops to jellybean-like structures.

    “It is almost like measuring snowflakes — it is difficult to get two that are identical,” Buonassisi says.

    Once the path planner finds the shortest path, it sends signals to the robot’s motors, which manipulate the probe and take measurements at each contact point in rapid succession.

    Key to the speed of this approach is the self-supervised nature of the neural network model. The model determines optimal contact points directly on a sample image — without the need for labeled training data.

    The researchers also accelerated the system by enhancing the path planning procedure. They found that adding a small amount of noise, or randomness, to the algorithm helped it find the shortest path.

    “As we progress in this age of autonomous labs, you really do need all three of these expertise — hardware building, software, and an understanding of materials science — coming together into the same team to be able to innovate quickly. And that is part of the secret sauce here,” Buonassisi says.

    Rich data, rapid results

    Once they had built the system from the ground up, the researchers tested each component. Their results showed that the neural network model found better contact points with less computation time than seven other AI-based methods. In addition, the path planning algorithm consistently found shorter path plans than other methods.

    When they put all the pieces together to conduct a 24-hour fully autonomous experiment, the robotic system conducted more than 3,000 unique photoconductance measurements at a rate exceeding 125 per hour.

    In addition, the level of detail provided by this precise measurement approach enabled the researchers to identify hotspots with higher photoconductance as well as areas of material degradation.

    “Being able to gather such rich data that can be captured at such fast rates, without the need for human guidance, starts to open up doors to be able to discover and develop new high-performance semiconductors, especially for sustainability applications like solar panels,” Siemenn says.

    The researchers want to continue building on this robotic system as they strive to create a fully autonomous lab for materials discovery.

    Reference: Siemenn AE, Das B, Ji K, Sheng F, Buonassisi T. A self-supervised robotic system for autonomous contact-based spatial mapping of semiconductor properties. Sci Adv. 2025;11(27):eadw7071. doi: 10.1126/sciadv.adw7071

    This article has been republished from the following materials. Note: material may have been edited for length and content. For further information, please contact the cited source. Our press release publishing policy can be accessed here.

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  • Watch Blackpink Debut New Song ‘Jump’ at Tour Opener in South Korea

    Watch Blackpink Debut New Song ‘Jump’ at Tour Opener in South Korea

    The girl group kicked off their Deadline tour at Goyang Stadium on Saturday night

    Blackpink debuted a new song, titled “Jump,” during the opening night of their world tour at Seoul’s Goyang Stadium. The dance-ready track is reportedly the band’s forthcoming reunion single and is expected to be released later this week.

    The group reunited over the weekend for their first live performance together in nearly two years. The concert, which was attended by BTS member J-Hope, marked the opening night of Blackpink’s Deadline tour. The singers performed 21 songs, with “Jump” coming towards the end of the set.

    Blackpink previously confirmed they planned to debut a new song during the South Korea concert. In June, the group’s record label, YG Entertainment, announced that the band was filming for a new music video. “We are filming in Korea with a famous overseas director,” the label said in a statement. “This will create another iconic music video that encapsulates Blackpink’s identity and musical color.” 

    Blackpink will perform 18 shows on the Deadline tour, which marks the musicians’ comeback as a group. It kicks off in Seoul before four shows in North America: in Los Angeles, Toronto, Chicago, and New York in mid-July. The band will also play at Japan’s Tokyo Dome in mid-January 2026.

    Trending Stories

    The group’s last album arrived in 2022 with Born Pink. While speaking to Tyla for Rolling Stone‘s Musicians on Musicians issue last year, Lisa shared her excitement about reuniting with her fellow members. “By next year, I think I would just keep releasing music and get together with the girls. I can’t wait to share with the girls what I’ve been doing,” she said at the time.

    In May, after launching her Bose collaboration, Lisa told Variety that a new Blackpink was “coming soon, I promise.” She added, “We’re all so super excited to get back together and go on tour. We really miss the blinks. We can’t wait to see them.”

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  • King Abdulaziz International Airport receives the first British Airways flights from London | Jeddah Airports Company

    King Abdulaziz International Airport receives the first British Airways flights from London | Jeddah Airports Company

    King Abdulaziz International Airport received the first direct British Airways flights coming from Heathrow Airport in London, as the company began operating its flights between the two airports at a rate of (6) flights per week, giving travelers additional options for traveling between the two destinations.

    Eng. Mazen bin Mohammed Johar, CEO of Jeddah Airports Company, praised this cooperation with British Airways to operate regular flights between London and Jeddah, pointing out that this coincides with the growing demand for travel between the Kingdom of Saudi Arabia and the United Kingdom, and the selection of King Abdulaziz International Airport as a preferred international destination for major global airlines, as it is a hub airport linking East and West, thanks to its distinguished geographical location and the capabilities it provides to provide a comfortable travel experience that exceeds travelers’ expectations.

    Jawhar pointed out that this step comes as part of Jeddah Airports’ strategy to increase the number of travel destinations linked to King Abdulaziz International Airport, in implementation of the national strategy for the aviation sector, which is in line with Saudi Vision 2030. The strategy aims to connect the airport to 150 international destinations, serve 114 million passengers, and handle 2.5 million tons of cargo by 2030.

    For his part, Neil Shernoff, Executive Director of Planning and Strategy at British Airways, said: “We are excited to be operating the air route to King Abdulaziz International Airport again within our network, having last operated a scheduled flight in 2021.

    He pointed out that British Airways has a long history of facilitating travel for families, friends, and businesses in the Kingdom of Saudi Arabia to and from Heathrow Airport in the capital.

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  • Apple takes fight against $587 million EU antitrust fine to court – Reuters

    1. Apple takes fight against $587 million EU antitrust fine to court  Reuters
    2. Apple files appeal against 500 million euro EU fine  Profit by Pakistan Today
    3. Apple to Delay Some Feature Rollouts in EU, Citing Regulatory Hurdles  WSJ
    4. Europeans to miss certain iOS 26 features due to strict EU regulations – GSMArena.com news  GSMArena.com
    5. Apple Appeals ‘Unprecedented’ €500 Million EU App Store Fine  Bloomberg

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  • AI-powered 4K QD-OLED Smart Monitor That Transforms Work, Streaming and Gaming – Samsung Newsroom India

    AI-powered 4K QD-OLED Smart Monitor That Transforms Work, Streaming and Gaming – Samsung Newsroom India

    Flagship M9 model sets new visual standard and updated M8 and M7 extend AI-powered ease of use

    The Smart Monitor series continues to evolve based on how people work, watch and play

    Consumers can avail launch benefits with an instant cart discount up to INR 3000 between July 7 and July 20, 2025

     

    Samsung, India’s largest consumer electronics brand, announced its all-new Smart Monitor family, featuring the luxurious M9 (M90SF), alongside enhanced editions of the M8 (M80SF) and M7 (M70F). With advanced AI features across the lineup, the new offerings provide a more personalized and connected screen for work and entertainment.

     

    “By combining Samsung’s 4K QD-OLED brilliance with intuitive vision AI, the M9 elevates the display into something more than a monitor. With real time picture and sound optimization, a sleek all-in-one design and seamless access to your favorite streaming and work tools, the M9 delivers a sharper, smarter and truly immersive experience,” said Puneet Sethi, Vice President, Enterprise Business, Samsung India.

     

    Flagship M9: A Leap in Display Innovation

    The M9 introduces QD-OLED technology to the Smart Monitor lineup for the first time. Merging flagship-level visuals with TV-grade smart functionality, the 32-inch M9 is engineered to deliver stunning contrast, vibrant colors, and immersive visuals. With a sleek, all-metal chassis, it blends museum-quality aesthetics with functional elegance, apt for a chic design studio or the coveted corner office.

     

    Samsung’s Smart Monitor M9 introduces OLED Safeguard+ to maintain screen integrity over time, featuring a proprietary cooling system that minimizes the risk of burn-in. Its Glare-Free display reduces reflections, ensuring consistent visibility and comfort even in bright environments.

     

    The M9 leverages AI-driven technologies like AI Picture Optimizer, 4K AI Upscaling Pro, and Active Voice Amplifier (AVA) Pro to enhance picture and sound quality in real time, adapting automatically to content and surroundings for optimized performance.

     

    As a smart entertainment hub, the M9 offers access to popular streaming apps, Samsung TV Plus, and Samsung Gaming Hub, enabling cloud-based gaming without a console or PC. With a 165Hz refresh rate, 0.03ms response time, and NVIDIA G-SYNC compatibility, it delivers smooth, high-performance visuals ideal for gaming and other demanding tasks.

     

    Paired with its 4K QD-OLED display, the monitor delivers visuals that align with content creators’ intentions, offering clarity and confidence for any application.

     

    M8 and M7: Smarter Everyday Displays for Work and Play

    The Smart Monitor M8 and M7 expand Samsung’s smart monitor lineup with 32-inch 4K UHD screens powered by advanced VA panel technology for sharp detail and rich contrast. Both models feature AI-powered tools like Click to Search and Tizen OS Home for intuitive content discovery and personalized recommendations.

     

    All three models integrate seamlessly with SmartThings, support Multi Control between Samsung devices, and offer Multi View for multitasking. With Microsoft 365 access, users can create and edit documents directly from the monitor without a PC, making them versatile solutions for modern work and entertainment setups.

     

    Prices and Offers

     

    Model Price (in INR) Coupon/add to cart (in INR)
    M90SF 32” 125999 3000
    M80SF 31” 49299 3000
    M70F 32″ (Black) 30699 1500
    M70F 32″ (White) 31199 1500
    M70F 43” 34299 1500

     

    As a part of launch starting from July 7 and July 20, 2025, consumers can avail benefits with instant cart discount up to INR 3000 across all channels.

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  • Scintillating clashes expected as The World Games draw made in Switzerland

    The draws for the men’s and women’s beach handball competitions of The World Games 2025 have been made today (Monday 7 July) at the International Handball Federation (IHF) headquarters in Basel, Switzerland.

    The World Games 2025 (TWG 2025) will take place in Chengdu, People’s Republic of China, from 7 to 17 August, with beach handball competitions running from 7 to 12 August. The draw took place exactly one month before games throw-off and was made by Hristo Boskoski, responsible for beach handball in the IHF Office.

    The men’s and women’s competitions at Chengdu 2025 will feature eight teams in each competition drawn into two preliminary groups of four teams each.

    Teams were drawn from four pots, with seedings based on their rankings at the 2024 IHF Men’s and Women’s Beach Handball World Championships. As hosts, China had the right to choose the group they will compete in.

    The women’s TWG 2025 competition draw was made first, with Croatia first out of the pot. The 2009 silver medallists were drawn into group B, with Asian champions Vietnam following, drawn into group A.

    2017 bronze medallists Spain were then drawn into group A, with Portugal moving into group B. World Championship and The World Games title-holders Germany were out of the pot next, drawn into group A, with The World Games bronze medallists Argentina drawn into group B.

    At this point, the draw paused for the Chinese Handball Association to choose which group they wanted to be in and they chose group B, meaning that Denmark moved into group A.

    In the men’s draw, three-time The World Games gold medallists Brazil (2009, 2013, 2017) were first out of the bowl and drawn in group A, with debutants Tunisia moving into group B. Germany, who finished fourth in 2005, were then drawn into group A, with 2001 and 2005 silver medallists Spain drawn into group B.

    Reigning The World Games and IHF World Championship champions Croatia were drawn into group A, where they will renew their long-term rivalry with Brazil.

    Denmark, who Croatia beat in the final of the 2024 IHF Men’s Beach Handball World Championship in China last year, were then drawn into group B, joined by the hosts themselves, who made the decision to be in the group which features three continents. To conclude the draw, Portugal were then drawn into group A.

    The draw can be watched again on the IHF YouTube channel HERE.

    Women’s competition

    Group A
    Vietnam (VIE)
    Spain (ESP)
    Germany (GER) 
    Denmark (DEN)

    Group B
    Croatia (CRO) 
    Portugal (POR) 
    Argentina (ARG)
    People’s Republic of China (CHN)

    Men’s competition

    Group A
    Brazil (BRA) 
    Germany (GER)
    Croatia (CRO)
    Portugal (POR)

    Group B
    Tunisia (TUN)
    Spain (ESP)
    Denmark (DEN)
    People’s Republic of China (CHN)

    For more information about how the teams qualified, visit HERE.

    The World Games is a multi-sport event staged every four years by the IWGA, organised with the support of the International Olympic Committee.
     
    Chengdu 2025 will be the 12th edition of The World Games, the most recent being held in Birmingham, USA, last July, with 3,600 athletes from 34 sports and 100 countries taking part.

    Beach handball has been part of The World Games since it was introduced as a demonstration/invitational sport in Japan in 2001. It followed in Germany (2005) and Chinese Taipei (2009), before becoming a full sport at the 2013 edition in Colombia and then continuing in Poland (2017), before the USA (2022), where Croatia (men) and Germany (women) won the beach handball titles.

    The 12th edition of The World Games will take place from 7 to 17 August 2025 in Chengdu, People’s Republic of China with Beach Handball one of over 30 sporting disciplines on the event programme. 

    For further information, visit www.theworldgames.org.

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  • Iran: Endgame regime change? – Democracy and society

    Iran: Endgame regime change? – Democracy and society

    Since Israel bombed Iranian cities for 12 days in a military campaign that breached international law, the prospect of a political shift away from the Islamic Republic has been dangled more explicitly and frequently than before. Potential contenders for leadership in a new regime in Tehran have been saying they are ready to lead a smooth and peaceful transition without engendering instability.

    Powerful factions within the Iranian diaspora either endorsed Israel’s war effort or ignored the huge loss of civilian life lest their denunciation of violence overshadowed the imminence of a desired regime change. And some disgruntled Iranians inside the country, weary of corruption and repression, found themselves in agreement.

    The conviction that the ultimate solution to the ongoing political, economic and social crises implicating Iran is the replacement of its government appears to have been embraced by pro-democracy voices globally as preordained. Domestically, the idea has been gaining traction and larger numbers of Iranian taxpayers say they don’t believe gradual reform can improve their lives. Still, the most vocal regime change campaigners are the exiles.

    Silver bullet regime change?

    Despite the multiplicity of diasporic opposition groups and advocacy organisations representing them, almost no structured study is available that captures the political allegiances of the wide spectrum of Iranian expats. Perhaps one statistical gauge of their sweeping antipathy to the ruling establishment is their reaction to Iran’s electoral races.

    In the 2024 snap presidential election, of the nearly 3.5 million eligible voters overseas, only a total of 88 000 people cast their ballot at 234 polling stations set up at Iran’s consulates. Although a campaign of voter suppression orchestrated by transnational pressure groups prevented many potential voters from going to the polls, the abysmal turnout carried an unmistakable message.

    Temperamental social media reactions to events, manipulated by AI algorithms, can highly likely alter our perception of reality. But if social media are to be seen as windows into communities, the outpouring of morbid curiosity in Israel’s attacks, often marked by schadenfreude, was the dominant thread in the online conversations of Persian expats. They were convinced the endgame would be regime change. But they weren’t the only ones relishing in Israel’s muscle-flexing.

    The spectacle of the Revolutionary Guards commanders being killed in the first days of the attacks electrified some Iranians at home who were desperate and jaundiced. As the airstrikes expanded countrywide and ordinary citizens were killed indiscriminately, revulsion against the war and the denunciation of the aggressor grew in intensity.

    For the past several months, rapid outages have caused Iran’s industries and businesses $219 million in damages every day.

    Notwithstanding the present ceasefire, leaders of the diasporic opposition, including the well-known figureheads, icons of Iran’s former royal family and the more organised dissidents such as the Mujahedin-e Khalq Organization (MEK) remain the champions of a putsch. They say such a political rearrangement will transform life in Iran, reversing a long stretch of isolation.

    Arguments against the urgency of fundamental change are at best deficient. The status quo is beyond unsustainable. Nearly five decades of cultural crackdown, economic disarray caused by crushing sanctions and incompetent leadership, and the persistent climate of fear surrounding minorities and women have spawned a state of lingering misfortune.

    While Qatar and Saudi Arabia have been able to secure the hosting rights of the different editions of the FIFA World Cup, Iran spent nearly $23 million on renovating its oldest football venue, only to acknowledge after its re-opening that the work was done partially. The Azadi Stadium was crippled by a 17-minute-long electricity blackout during an international match in March.

    The embarrassment was not just the power grid going off at a soccer venue. For the past several months, rapid outages have caused Iran’s industries and businesses $219 million in damages every day. The challenge is the delusional thinking of an ambitious state that is not even equipped to supply reliable electricity to its citizens.

    But if a democratic shift is inevitable, and if the proponents believe such a change is so urgent that it justifies foreign military intervention and increased economic punishment, there is a more substantive question to be answered first: How is the Iranian society going to reintegrate with the community of nations without any investment being made in the prerequisites?

    The importance of civic education

    Automatic assumptions about the aftermath of political transformation in Iran promise the vision of a country where the rule of law is swiftly restored, technological advances take off overnight, work ethics dominate the administrative setup, and human rights come to the forefront of policymaking. Iran’s trials are painted as being created entirely by one source, namely the ayatollah, and they will allegedly be resolved once he is toppled.

    No counterproposal to this fallacy absolves Iran’s theocracy of the stagnation and mayhem it has wrought after years of failed governance. But the crusaders of change are yet to share their thoughts on how they plan to recalibrate the social fabric of a nation that has consistently been denied the chance to hear about the rule of law, civic engagement and tolerance.

    Harrowing reports of honour killing, the continued practice of child marriage and the admissibility of polygamy in different regions of a country boasting an otherwise educated population are also part of the reality of the 21st-century Iran. These are condoned by the establishment, but don’t originate from the presidential office. They are happening across villages and towns with unique ethnoreligious profiles, and in Tehran.

    Structural corruption has implanted unethical arrangements into the everyday routine of the functionaries who have become viscerally resistant to transparency.

    Iran’s school curriculum includes little to no material about criminal justice, travel, climate change, racial equity, reproductive health and sex education. A senior female seminarian said in a 2023 interview that in line with Islamic teachings, children must be nurtured to be ‘ignorant’ about issues pertaining to sexuality and gender. Moreover, both the primary and secondary school curricula have been repeatedly modified to accommodate heavily-indoctrinated materials around contemporary politics. Yet, the absence of a national context on good citizenship does not end at the school where formal learning happens.

    Last year, the Iranian Legal Medicine Organization reported that 19 435 people were killed in road accidents. In the World Health Organization’s regional subset of the Eastern Mediterranean consisting of 20 countries, Iran’s per-capita road traffic death rate is the seventh largest, even higher than Pakistan with a population three times the size of Iran.

    The police dedicating the bulk of their resources to cultural surveillance has infantilised the value of safe driving in the national discourse, and a robust debate about responsible traffic behaviour has not ever happened.

    Structural corruption

    In addition, if the administrative bureaucracy is known for its sluggishness and inefficiency, it is not merely because the system cannot abjure excessive paperwork or innovate solutions. Structural corruption has implanted unethical arrangements into the everyday routine of the functionaries who have become viscerally resistant to transparency.

    Draining sanctions that have blocked the presence of international organisations and non-profits in Iran mean corruption can metastasise when independent oversight is unavailable, afflicting the private sector and independent professionals, as well.

    Physicians, lawyers and business owners are increasingly relying on under-the-table payoffs to do their daily tasks. Even foreign embassies in Tehran, which take instructions from their respective capitals, have become accustomed to these practices, accepting bribes from visa applicants to assign them appointments.

    The TRACE Bribery Risk Matrix 2024, has listed Iran as the 185th country in a ranking of 194 nations assessed for the prevalence of bribery in their business and government sector and their compliance with anti-bribery measures.

    The contenders for power in a free Iran have similarly refused to state their views on how they will save millions of Iranians consumed by corrupt structures if they have indeed diagnosed the roots of the problem.

    Now, if there is a valid argument that the unreformable Islamic Republic needs to be succeeded by a democracy so that these challenges are overcome, the commitment of the proponents to the process remains uncertain. They have not clarified how the social amendments that ensure any political change would be lasting can be facilitated.

    The contenders for power in a free Iran have similarly refused to state their views on how they will save millions of Iranians consumed by corrupt structures if they have indeed diagnosed the roots of the problem. We don’t know their perspective on the importance of civic education, engagement with discordant voices, and cultural and religious tolerance.

    As they presently fulfil the role of the spiritual chieftains of the diasporic collectives, there is no indication that they are preparing their de facto constituents to become global citizens of a democratic Iran. If anything, these leaders haven’t honoured the notion of good citizenship by mobilising their staunch supporters to storm events and stifle speech online.

    Let’s picture the immediate overthrow of the Islamic Republic and a transitional process bringing an exiled luminary to power. How is the new leader going to change the collective identity of a society in which for the past 46 years, observing the traffic light, taking turns in a bakery line, and interacting with religious and sexual minorities as colleagues have not ever been questions to reflect on?

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  • How Magnesium and Vitamin D Can Help Manage Anxiety

    How Magnesium and Vitamin D Can Help Manage Anxiety

    Magnesium and vitamin D are both supplements that may help with anxiety. Low levels of magnesium or vitamin D in your body may increase your risk of anxiety, and improving your levels by taking supplements or eating certain foods may help you feel less anxious.

    Magnesium and vitamin D may help decrease your stress and anxiety levels, and taking them together may help both work better in your body.

    Magnesium and Anxiety

    Magnesium helps your body react to physical and mental stress. Getting enough magnesium may help decrease the levels of the stress hormone cortisol in your body. On the other hand, low magnesium levels can raise your body’s stress levels.

    What the research says: Studies suggest that magnesium supplements may help ease anxiety symptoms in some people. A review of eight studies found that half reported an improvement in anxiety symptoms with magnesium supplements. Researchers shared that more high-quality studies are needed to better understand the benefits of magnesium for anxiety.

    Vitamin D and Anxiety

    Vitamin D plays a role in brain health and psychiatric health. People with low vitamin D levels may be more likely to have anxiety.

    What the research says: Many studies suggest that taking vitamin D can improve anxiety and related symptoms. Adults with generalized anxiety disorder who took vitamin D once a week for three months saw a significant improvement in their anxiety symptoms and levels of serotonin (a brain chemical that helps with your mood, sleep, and emotions).

    The Benefit of Combining Them

    Magnesium helps make vitamin D useful in your body. If magnesium levels are low, your body will have difficulty processing and using vitamin D. Taking them together may boost the benefits.

    Researchers haven’t agreed on a recommended dosage for magnesium, vitamin D, or both for managing anxiety.

    In general, the recommended daily intake for magnesium is:

    • Children 1-18 years: 80-400 milligrams (mg)
    • Adult men: 400-420 milligrams
    • Adult women: 310-400 milligrams

    Your recommended intake may depend on your age and whether you are pregnant or breastfeeding.

    The recommended daily intake for vitamin D is:

    • Children 1-18 years: 600 international units (IU)
    • Adults under 70: 600 international units
    • Adults above 70: 800 international units

    Should you take them together? It is safe to take magnesium and vitamin D together. While more research is needed to better understand whether taking them together or separately is better for anxiety, some research suggests that they help each other work better if you use them at the same time.

    You can also increase your magnesium and vitamin D levels by adding foods high in both to your diet.

    Foods high in magnesium include:

    • Green leafy vegetables
    • Whole grains
    • Nuts
    • Seeds

    Food sources of vitamin D include:

    • Fatty fish (like salmon, tuna, and trout)
    • Fish liver oils
    • Egg yolks
    • Cheese
    • Fortified milk

    Ultraviolet (UV) rays from the sun help your body create vitamin D naturally, so exposure to the sun can help increase these levels.

    Nutrition is important when it comes to managing anxiety. One group of researchers found that diets high in fat, sugar, and refined carbohydrates may be connected to higher levels of anxiety. More balanced diet patterns, including the Mediterranean diet, anti-inflammatory diet, low-calorie diet, and vegan diet, may help improve your nutrition and reduce anxiety.

    Other ways to manage anxiety include:

    • Seek professional help: Talking to a trained therapist can help you learn how to manage your anxiety and stress.
    • Take time to relax: Meditating, getting a massage, or listening to music are all examples of taking time out of your busy day to relax and de-stress.
    • Get regular physical activity: Getting regular exercise helps your physical health and can also improve anxiety and mental health.
    • Practice self-care: Making time for self-care can help ease anxiety symptoms. Everyone’s definition of self-care is different, but consider talking to a friend, journaling, taking a walk, or doing an activity you love.
    • Avoid or limit stimulants: Caffeine, coffee, and alcohol can affect your stress levels and make you more anxious.

    Consider talking to a healthcare provider if you have symptoms such as:

    • Difficulty sleeping or getting a good night’s rest
    • Difficulty controlling your anxiety and emotions
    • Anxious thoughts, feelings, or behaviors that interfere with your daily life
    • Persistent sadness
    • Thoughts of hurting yourself or others

    Taking magnesium and vitamin D supplements can help restore low levels that may be associated with a higher risk of anxiety. Both supplements have some research to support their effectiveness in managing anxiety, and other research suggests they work better together.

    Talk with your healthcare provider if you are interested in taking magnesium or vitamin D for anxiety. They can help you decide if the supplements are a safe option for you. You can also get more magnesium and vitamin D by eating foods rich in these nutrients.

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  • 9 Healthcare Startups Next in Line to Go Public, According to Bankers

    9 Healthcare Startups Next in Line to Go Public, According to Bankers

    Transcarent contracts with employers to provide health navigation and virtual care to employees. The startup looks a lot closer to an exit after a big acquisition earlier this year.

    The startup bought the public health benefits company Accolade in a $621 million deal that closed in April. The acquisition looks to have significantly increased Transcarent’s customer base and thus made a big contribution to its top line — before the Transcarent deal, Accolade said it contracted with over 1,400 employers and health plans, and the company reported $414 million in revenue in the fiscal year 2024. Now, with Accolade on board, Transcarent says it works with over 1,700 employers and health plans. Transcarent hasn’t publicly shared its revenue.

    The Accolade acquisition was financed by Transcarent investors including General Catalyst and CEO Glen Tullman’s 62 Ventures, cash on Transcarent’s balance sheet, and debt provided by JP Morgan. Transcarent has raised about $450 million since its 2020 founding, including $126 million in a Series D funding round in May 2024 at a $2.2 billion valuation.

    Tullman has by far the most experience with taking companies public of the CEOs on this list. Before Transcarent, he led three companies through public listings — Livongo, Allscripts, and Enterprise Systems. His success with Livongo, the diabetes care company he founded, stands out as a rare example of blockbuster digital health returns; Livongo went public in 2019 at a $2.5 billion valuation, before being acquired by Teladoc the next year for $18.5 billion, at the time the biggest deal ever in the digital health market.

    That experience could set Transcarent up to pursue an IPO when market conditions look favorable. Tullman told MedCity News in May 2024 that he had “no interest” in selling the company, but would consider an IPO in the future.

    Transcarent will have to separate itself from previous care navigation IPOs, however, including Health Catalyst, whose stock has declined more than 85% since its 2019 IPO. It’ll also need to contend with Accolade’s cash burn, since the health benefits company reported a net loss of $100 million in the fiscal year 2024.

    In a statement to BI, Tullman said Transcarent is focused on integrating its solutions to bring its AI-powered platform, called WayFinding, to more members and employers to make healthcare more accessible and affordable.

    “At Transcarent, our priority is meeting the needs of our Members and delivering measurable results for our clients. If we do those things well, the rest will follow,” Tullman said.


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