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  • Engineered Salmonella therapy delivers immune payloads to combat cancer

    Engineered Salmonella therapy delivers immune payloads to combat cancer

    A new research paper was published in Volume 16 of Oncotarget on October 6, 2025, titled “ACTM-838, a novel systemically delivered bacterial immunotherapy that enriches in solid tumors and delivers IL-15/IL-15Rα and STING…

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  • IMF chief warns of economic uncertainty and offers this advice: ‘Buckle up’

    IMF chief warns of economic uncertainty and offers this advice: ‘Buckle up’

    WASHINGTON — WASHINGTON (AP) — The global economy is holding up better than expected despite major shocks such as President Donald Trump’s tariffs, but the head of the International Monetary Fund says that resilience may not last.

    “Buckle up,” Managing Director Kristalina Georgieva says in prepared remarks to a think tank Wednesday. “Uncertainty is the new normal and it is here to stay.”

    Her comments at the Milken Institute come on a day when gold prices hit $4,000 an ounce for the first time as investors seek safe haven from a weaker dollar and geopolitical uncertainty and before the IMF and World Bank hold their annual meetings next week in Washington. Trump’s trade penalties are expected to be in sharp focus when global finance leaders and central bankers gather.

    The worldwide economy is forecast to grow by 3% this year, and Georgieva is citing a number of factors for why it may not slip below that: Countries have put in place decisive economic policies, the private sector has adapted and the tariffs have proved less severe than originally feared.

    “But before anyone heaves a big sigh of relief, please hear this: Global resilience has not yet been fully tested. And there are worrying signs the test may come. Just look at the surging global demand for gold,” she says in her prepared remarks.

    On Trump’s tariffs, she says “the full effect is still to unfold. In the U.S., margin compression could give way to more price pass-through, raising inflation with implications for monetary policy and growth.”

    The Republican administration imposed import taxes on nearly all U.S. trading partners in April, including Canada, Mexico, Brazil, China and even the tiny African nation of Lesotho. “We’re the king of being screwed by tariffs,” Trump said Tuesday in the Oval Office during a meeting with Canadian Prime Minister Mark Carney.

    While the U.S. has announced some trade frameworks with nations such as the United Kingdom and Vietnam, the tariffs have created uncertainty worldwide.

    “Elsewhere, a flood of goods previously destined for the U.S. market could trigger a second round of tariff hikes,” Georgieva says.

    The Supreme Court next month will hear arguments about whether Trump has the authority to impose some of his tariffs under the International Emergency Economic Powers Act.

    In her wide-ranging remarks, Georgieva points to youth discontent around the world as many young people foresee a future where they earn less than their parents. She also is calling for greater internal trade in Asia, more business friendly changes in Africa and more competitiveness in Europe.

    For the United States. Georgieva is urging the government to address the federal debt and to encourage household saving.

    The IMF is a 191-country lending organization that seeks to promote global growth and financial stability and to reduce poverty.

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  • Waze Rolls Out Voice Reporting for Easy Flagging of Roadblocks, Traffic Issues – PCMag

    1. Waze Rolls Out Voice Reporting for Easy Flagging of Roadblocks, Traffic Issues  PCMag
    2. Waze just made your drive even safer, here’s how  Currently.com
    3. Waze just made hazard reporting as easy as talking  Android Police
    4. No more tapping menus: Waze…

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  • “Fit for the Future”, a call for athletes to share ideas and help shape the Olympic Movement

    “Fit for the Future”, a call for athletes to share ideas and help shape the Olympic Movement

    “Fit for the Future,” a new initiative which consults active and retired Olympians, has been launched.

    The consultation was created by International Olympic Committee (IOC) President, Kirsty Coventry, to gather the thoughts and opinions of…

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  • ‘Expedition 33’ will get a free update as French studio takes victory lap – The Washington Post

    1. ‘Expedition 33’ will get a free update as French studio takes victory lap  The Washington Post
    2. Clair Obscur: Expedition 33 Is Getting a Free Update Featuring New Dungeon, Enemies, Bosses, and Costumes  IGN
    3. Clair Obscur: Expedition 33 sales top…

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  • Reality TV star Georgia Harrison to be appointed OBE at Windsor Castle

    Reality TV star Georgia Harrison to be appointed OBE at Windsor Castle

    Getty Images Georgia Harrison, a blonde woman wearing a blue and white stripy shirt and a grey coat, holding a piece of paper and making a speech in front of a selection of signs warning that social media companies do not take reports of abuse against women and girls seriously.Getty Images

    Georgia Harrison became a campaigner on tackling violence against women and girls since since her ex-partner was jailed for posting an intimate video of her online

    A reality TV celebrity who has campaigned for safety for women and…

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  • PPP, PML-N should resolve issues, move forward: Rana Sanaullah – Dawn

    1. PPP, PML-N should resolve issues, move forward: Rana Sanaullah  Dawn
    2. Why are PPP and PML-N currently feuding?  Dawn
    3. Maryam vows to keep speaking for Punjab  The Express Tribune
    4. PM Shehbaz summons senior party leaders to ease tensions with PPP  Dunya…

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  • Live updates: Gaza ceasefire talks resume in Egypt as Israel intercepts another aid flotilla

    Live updates: Gaza ceasefire talks resume in Egypt as Israel intercepts another aid flotilla

    Arab nations have condemned far-right Israeli minister Itamar Ben Gvir after he prayed at Jerusalem’s most sensitive holy site today, despite a decades-old…

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  • Vitiligo Disease Duration Linked to Depression Severity | Dermatology Times

    Vitiligo Disease Duration Linked to Depression Severity | Dermatology Times

    Emotional distress, including anxiety, depression, and stress, is prevalent among patients with vitiligo, often exacerbating disease perception and treatment adherence.1 While physical activity (PA) is known to mitigate psychological symptoms in…

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  • TAG Heuer × New Balance Connected Calibre E5

    TAG Heuer × New Balance Connected Calibre E5

     

    For more than a century, sport has been the crucible in which the art of timekeeping was forged into science. The earliest wrist chronographs were built to time laps on racetracks and record splits at marathons. From the first Olympic…

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