De-escalation of dual antiplatelet therapy provides benefits in patients after coronary artery bypass grafting


Notes to editor

This press release accompanies both a presentation and an ESC press conference at ESC Congress 2025.  

It does not necessarily reflect the opinion of the European Society of Cardiology.  

 

Funding: The study was funded by the National Clinical Research Centre for Cardiovascular Diseases (NCRC2022001). 

Disclosures: Doctor Yuan reports that all authors declare no relevant conflicts of interest. 

References and notes

1‘The TOP-CABG trial’ presented during HOT LINE 10 on 1 September 2025 at 14:21 to 14:31 in Madrid (Main Auditorium). 

2Xenogiannis I, Zenati M, Bhatt DL, et al. Saphenous vein graft failure: From pathophysiology to prevention and treatment strategies. Circulation. 2021;144:728−745. 

3Sandner S, Redfors B, Angiolillo DJ, et al. Association of dual antiplatelet therapy with ticagrelor with vein graft failure after coronary artery bypass graft surgery: A systematic review and meta-analysis. JAMA. 2022;328:554–562. 

 

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About ESC Congress 2025 

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