Cassava starch patch breakthrough in Kerala could aid treatment of mouth disorders, oral cancer

Cassava starch patch offers cost-effective, long-lasting treatment for oral disorders including leukoplakia and injuries.

Cassava starch patch breakthrough in Kerala could aid treatment of mouth disorders, oral cancer
Cassava starch patch- Cassava | Photos: Mathrubhumi, Canva

Thiruvananthapuram: Scientists have made a breakthrough in the treatment of mouth disorders and injuries. A patch made from cassava starch has been developed to prolong the effect of medicines for white patches (leukoplakia) and other conditions. The small, film-like patches are being developed through joint research at Sree Chitra Tirunal Institute for Medical Sciences and Technology and the Central Tuber Crops Research Institute (CTCRI).

Leading scientists at the forefront

CTCRI Principal Scientist Dr A.N. Jyothi and Sree Chitra scientist Dr Manoj Komath are leading the experiments. CTCRI is handling the manufacturing of the starch sheets, determining the correct drug dosage, and ensuring proper integration into the films. Once ready, the patches will be sent to Sree Chitra for trials related to oral application.

Potential impact on cancer treatment

The research is expected to assist even in cancer treatment. The cassava starch is ground into a paste to create patches that can adhere inside the mouth, similar to a plaster. Trials showed that the patches remain in place for up to two hours without causing discomfort. They do not loosen when rinsing the mouth or swallowing. Even if swallowed, it is not unsafe.

Cost-effective alternative to existing treatments

Unlike ointments, powders, or mouthwashes, which do not remain in the mouth for long, existing cellulose-fibre-based patches can last longer but are more expensive. This new cassava starch patch offers a cost-effective and patient-friendly alternative.

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