Frequency, lethality, and demographic trends of acute respiratory viruses in hospitalized patients: insights from a German tertiary care hospital from july 2022 to april 2023 | BMC Infectious Diseases

  • Galanti M, Birger R, Ud-Dean M, Filip I, Morita H, Comito D, et al. Rates of asymptomatic respiratory virus infection across age groups. Epidemiol Infect. 2019;147:e176. https://doi.org/10.1017/s0950268819000505. PubMed PMID: 31063096; PubMed Central PMCID: PMC6518513.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • van Asten L, van den Wijngaard C, van Pelt W, van de Kassteele J, Meijer A, van der Hoek W, et al. Mortality attributable to 9 common infections: significant effect of influenza A, respiratory syncytial virus, influenza B, norovirus, and parainfluenza in elderly persons. J Infect Dis. 2012;206(5):628–39. https://doi.org/10.1093/infdis/jis415.

    Article 
    PubMed 

    Google Scholar 

  • Schüz ML, Dallmeyer L, Fragkou PC, Omony J, Krumbein H, Hünerbein BL, et al. Global prevalence of respiratory virus infections in adults and adolescents during the COVID-19 pandemic: a systematic review and meta-analysis. Int J Infect Dis. 2023;137:16–24. https://doi.org/10.1016/j.ijid.2023.10.001.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Sonego M, Pellegrin MC, Becker G, Lazzerini M. Risk factors for mortality from acute lower respiratory infections (ALRI) in children under five years of age in low and middle-income countries: a systematic review and meta-analysis of observational studies. PLoS One. 2015;10(1):e0116380. https://doi.org/10.1371/journal.pone.0116380.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Coleman BL, Fadel SA, Fitzpatrick T, Thomas SM. Risk factors for serious outcomes associated with influenza illness in high- versus low- and middle-income countries: systematic literature review and meta-analysis. Influenza Other Respir Viruses. 2018;12(1):22–9. https://doi.org/10.1111/irv.12504.

    Article 
    PubMed 

    Google Scholar 

  • Falsey AR, McElhaney JE, Beran J, van Essen GA, Duval X, Esen M, et al. Respiratory syncytial virus and other respiratory viral infections in older adults with moderate to severe influenza-like illness. J Infect Dis. 2014;209(12):1873–81. https://doi.org/10.1093/infdis/jit839.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Mortality, morbidity, and hospitalisations due to influenza lower respiratory tract infections, 2017: an analysis for the Global Burden of Disease Study 2017. Lancet Respir Med. 2019;7(1):69-89. Epub 20181212. https://doi.org/10.1016/s2213-2600(18)30496-x. PubMed PMID: 30553848; PubMed Central PMCID: PMC6302221.

  • Nguyen-Van-Tam JS, O’Leary M, Martin ET, Heijnen E, Callendret B, Fleischhackl R et al. Burden of respiratory syncytial virus infection in older and high-risk adults: a systematic review and meta-analysis of the evidence from developed countries. Eur Respir Rev. 2022;31(166). Epub 20221115. https://doi.org/10.1183/16000617.0105-2022. PubMed PMID: 36384703; PubMed Central PMCID: PMC9724807.

  • Atamna A, Babich T, Froimovici D, Yahav D, Sorek N, Ben-Zvi H, et al. Morbidity and mortality of respiratory syncytial virus infection in hospitalized adults: comparison with seasonal influenza. Int J Infect Dis. 2021;103:489–93. PubMed PMID: 33249288.

    Article 
    PubMed 

    Google Scholar 

  • Kim Y-J, Boeckh M, Englund JA. Community respiratory virus infections in immunocompromised patients: hematopoietic stem cell and solid organ transplant recipients, and individuals with human immunodeficiency virus infection. Semin Respir Crit Care Med. 2007;28(02):222–42. https://doi.org/10.1055/s-2007-976494.

    Article 
    PubMed 

    Google Scholar 

  • Begley KM, Monto AS, Lamerato LE, Malani AN, Lauring AS, Talbot HK, et al. Prevalence and clinical outcomes of respiratory syncytial virus vs influenza in adults hospitalized with acute respiratory illness from a prospective multicenter study. Clin Infect Dis. 2023;76(11):1980–8. https://doi.org/10.1093/cid/ciad031.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Wee LE, Ko KKK, Ho WQ, Kwek GTC, Tan TT, Wijaya L. Community-acquired viral respiratory infections amongst hospitalized inpatients during a COVID-19 outbreak in Singapore: co-infection and clinical outcomes. J Clin Virol. 2020;128:104436.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Walker E, Ison MG. Respiratory viral infections among hospitalized adults: experience of a single tertiary healthcare hospital. Influenza Other Respir Viruses. 2014;8(3):282–92. https://doi.org/10.1111/irv.12237.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Gross JV, Judith M, Thomas CE. COVID-19 and healthcare workers: a rapid systematic review into risks and preventive measures. BMJ Open. 2021;11(1):e042270. https://doi.org/10.1136/bmjopen-2020-042270.

    Article 
    PubMed 

    Google Scholar 

  • Montgomery CM, Humphreys S, McCulloch C, Docherty AB, Sturdy S, Pattison N. Critical care work during COVID-19: a qualitative study of staff experiences in the UK. BMJ Open. 2021;11(5):e048124. https://doi.org/10.1136/bmjopen-2020-048124. Epub 20210518.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Coronavirus-Infektionszahlen in Bayern [Internet]. 2023. Available from: https://www.lgl.bayern.de/gesundheit/infektionsschutz/infektionskrankheiten_a_z/coronavirus/karte_coronavirus/

  • Coronavirus-Pandemie. Was geschah wann? Bundesministerium für Gesundheit; 2023 [updated 15.02.2023; cited 2023 20.10.2023]. Available from: https://www.bundesgesundheitsministerium.de/coronavirus/chronik-coronavirus

  • Kruger S, Leskien M, Schuller P, Prifert C, Weissbrich B, Vogel U, et al. Performance and feasibility of universal PCR admission screening for SARS-CoV-2 in a German tertiary care hospital. J Med Virol. 2021;93(5):2890–8. https://doi.org/10.1002/jmv.26770. Epub 20210215.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Wagenhäuser I, Knies K, Pscheidl T, Eisenmann M, Flemming S, Petri N, et al. SARS-CoV-2 antigen rapid detection tests: test performance during the COVID-19 pandemic and the impact of COVID-19 vaccination. eBioMedicine. 2024. https://doi.org/10.1016/j.ebiom.2024.105394.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • SARS-CoV-2: Virologische Basisdaten sowie Virusvarianten im Zeitraum von 2020–2022: Robert-Koch-Institut. 2023 [updated 23.09.2023]. Available from: https://www.rki.de/DE/Content/InfAZ/N/Neuartiges_Coronavirus/Virologische_Basisdaten.html

  • Digitales Impfquotenmonitoring zur COVID-19-Impfung: Robert-Koch-Institut. 2024 [updated 05.03.2024; cited 2024 05.03.2024]. Available from: https://www.rki.de/DE/Content/InfAZ/N/Neuartiges_Coronavirus/Daten/Impfquoten-Tab.html

  • Hyug Choi J, Sook Jun M, Yong Jeon J, Kim HS, Kyung Kim Y, Ho Jeon C, et al. Global lineage evolution pattern of sars-cov-2 in africa, america, europe, and asia: A comparative analysis of variant clusters and their relevance across continents. J Transl Int Med. 2023;11(4):410–22. https://doi.org/10.2478/jtim-2023-0118. Epub 20231220.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Ambrosch A, Luber D, Klawonn F, Kabesch M. Focusing on severe infections with the respiratory syncytial virus (RSV) in adults: risk factors, symptomatology and clinical course compared to influenza A / B and the original SARS-CoV-2 strain. J Clin Virol. 2023;161:105399. PubMed PMID: 36863135; PubMed Central PMCID: PMC9927795.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Chen X, Zhu Y, Shen L, Zhou D, Feng N, Tong Q. Efficacy and safety of nirmatrelvir/ritonavir in severe hospitalized patients with COVID-19 and in patients at high risk for progression to critical illness: a real-world study. J Intensive Care Med. 2024;39(8):742–50 (Epub 20240214. doi: 10.1177/08850666241228841. PubMed PMID: 38356292).

    Article 
    PubMed 

    Google Scholar 

  • Zhang Y, Wang X, Huang C, Yang H, Jiang C, Yu X, et al. Nirmatrelvir-Ritonavir reduced mortality in hospitalized patients with COVID-19 during the Omicron outbreak: Real-World evidence from Beijing. Infect Drug Resist. 2024;17:1367–77. https://doi.org/10.2147/idr.S445826. Epub 20240408.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Groeneveld GH, Marbus SD, Ismail N, de Vries JJC, Schneeberger P, Oosterheert JJ, et al. Effectiveness of oseltamivir in reduction of complications and 30-day mortality in severe seasonal influenza infection. Int J Antimicrob Agents. 2020;56(5):106155. https://doi.org/10.1016/j.ijantimicag.2020.106155. Epub 20200906.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Strategy considerations for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other respiratory viruses in the WHO European Region during autumn and winter 2022/23: protecting the vulnerable with agility, efficiency, and trust: World Health Organization. 2022 [updated 19.07.2022]. Available from: https://www.who.int/europe/publications/i/item/WHO-EURO-2022-5851-45616-65461

  • Prevalence and attributable health burden of chronic respiratory diseases. 1990–2017: a systematic analysis for the global burden of disease study 2017. Lancet Respir Med. 2020;8(6):585–96. https://doi.org/10.1016/s2213-2600(20)30105-3. PubMed PMID: 32526187; PubMed Central PMCID: PMC7284317.

    Article 

    Google Scholar 

  • Savic M, Penders Y, Shi T, Branche A, Pirçon J-Y. Respiratory syncytial virus disease burden in adults aged 60 years and older in high-income countries: a systematic literature review and meta-analysis. Influenza Other Respir Viruses. 2023;17(1):e13031. https://doi.org/10.1111/irv.13031.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Aw D, Silva AB, Palmer DB. Immunosenescence: emerging challenges for an ageing population. Immunology. 2007;120(4):435–46. https://doi.org/10.1111/j.1365-2567.2007.02555. Epub 20070215.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Saint-Criq V, Lugo-Villarino G, Thomas M. Dysbiosis, malnutrition and enhanced gut-lung axis contribute to age-related respiratory diseases. Ageing Res Rev. 2021;66:101235. https://doi.org/10.1016/j.arr.2020.101235.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Ehrenzeller S, Chen T, Vaidya V, Rhee C, Baker MA, Klompas M. Impact of SARS-CoV-2 prevention measures on non-SARS-CoV-2 hospital-onset respiratory viral infections: an incidence trend analysis from 2015–2023. Clin Infect Dis. 2023;77(12):1696–9. https://doi.org/10.1093/cid/ciad451.

    Article 
    PubMed 

    Google Scholar 

  • Strobl R, Misailovski M, Blaschke S, Berens M, Beste A, Krone M, et al. Differentiating patients admitted primarily due to coronavirus disease 2019 (COVID-19) from those admitted with incidentally detected severe acute respiratory syndrome corona-virus type 2 (SARS-CoV-2) at hospital admission: a cohort analysis of German hospital records. Infect Control Hosp Epidemiol. 2024. https://doi.org/10.1017/ice.2024.3.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Kang S, Zheng R. Distribution of the causes of fever of unknown origin in china, 2013–2022. J Transl Int Med. 2024;12(3):299–307. https://doi.org/10.2478/jtim-2024-0008. Epub 20240727.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

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