The discovery of benzodiazepines (BZDs) was part science, part fortunate coincidence. Frank Berger initially found mephenesin had calming effects but poor duration of action and potency.1 He later developed a longer-acting compound, meprobamate….

The discovery of benzodiazepines (BZDs) was part science, part fortunate coincidence. Frank Berger initially found mephenesin had calming effects but poor duration of action and potency.1 He later developed a longer-acting compound, meprobamate….