Superinfection promotes replication and diversification of defective HIV-1 proviruses in people with non-suppressible viraemia

Persistent viraemia despite long-term adherence to effective ART

Participant 1 (P1) is a male diagnosed with HIV-1 in 2019, at which time the plasma HIV-1 RNA was 1,240,000 copies per ml and the CD4+ T cell count was 8 cells per µl. He responded…

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