2019 ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD: the task force for diabetes, pre-diabetes, and cardiovascular diseases of the European society of cardiology (ESC) and the European association for the study of diabetes (EASD). Rev Esp Cardiol Engl Ed. 2020;73(5):404. https://doi.org/10.1016/j.rec.2020.04.007.
Rooney MR, Fang M, Ogurtsova K, et al. Global prevalence of prediabetes. Diabetes Care. 2023;46(7):1388–94. https://doi.org/10.2337/dc22-2376.
Google Scholar
Echouffo-Tcheugui JB, Selvin E. Prediabetes and what it means: the epidemiological evidence. Annu Rev Public Health. 2021;42(1):59–77. https://doi.org/10.1146/annurev-publhealth-090419-102644.
Google Scholar
Richter B, Hemmingsen B, Metzendorf MI, Takwoingi Y. Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia. Cochrane metabolic and endocrine disorders group. Ed Cochrane Database Syst Rev. 2018;2018(11). https://doi.org/10.1002/14651858.CD012661.pub2.
Tabák AG, Herder C, Rathmann W, Brunner EJ, Kivimäki M. Prediabetes: a high-risk state for diabetes development. Lancet. 2012;379(9833):2279–90. https://doi.org/10.1016/S0140-6736(12)60283-9.
Google Scholar
Gong D, Chen X, Yang L, et al. From normal population to prediabetes and diabetes: study of influencing factors and prediction models. Front Endocrinol. 2023;14:1225696. https://doi.org/10.3389/fendo.2023.1225696.
Google Scholar
Huang Z, Han Y, Hu H, Cao C, Liu D, Wang Z. Triglyceride to high-density lipoprotein cholesterol ratio is associated with regression to normoglycemia from prediabetes in adults: a 5-year cohort study in China. J Transl Med. 2023;21(1):868. https://doi.org/10.1186/s12967-023-04752-w.
Google Scholar
Gujral UP, Narayan KMV, Kandula NR, Liu K, Kanaya AM. Incidence of diabetes and prediabetes and predictors of glycemic change among South Asians in the USA: the MASALA study. BMJ Open Diabetes Res Care. 2020;8(1). https://doi.org/10.1136/bmjdrc-2019-001063.
Anjana RM, Shanthi Rani CS, Deepa M, et al. Incidence of diabetes and prediabetes and predictors of progression among Asian indians: 10-Year Follow-up of the Chennai urban rural epidemiology study (CURES). Diabetes Care. 2015;38(8):1441–8. https://doi.org/10.2337/dc14-2814.
Google Scholar
Akhter-Khan SC, Van Es W, Prina M, et al. Experiences of loneliness in lower- and middle-income countries: A systematic review of qualitative studies. Soc Sci Med. 2024;340:116438. https://doi.org/10.1016/j.socscimed.2023.116438.
Google Scholar
Richard A, Rohrmann S, Vandeleur CL, Schmid M, Barth J, Eichholzer M. Loneliness is adversely associated with physical and mental health and lifestyle factors: Results from a Swiss national survey. Bayer A, ed. PLOS ONE. 2017;12(7):e0181442. https://doi.org/10.1371/journal.pone.0181442.
Google Scholar
Hackett RA, Hudson JL, Chilcot J. Loneliness and type 2 diabetes incidence: findings from the english longitudinal study of ageing. Diabetologia. 2020;63(11):2329–38. https://doi.org/10.1007/s00125-020-05258-6.
Google Scholar
Song Y, Zhu C, Shi B, et al. Social isolation, loneliness, and incident type 2 diabetes mellitus: results from two large prospective cohorts in Europe and East Asia and Mendelian randomization. eClinicalMedicine. 2023;64:102236. https://doi.org/10.1016/j.eclinm.2023.102236.
Google Scholar
Henriksen RE, Nilsen RM, Strandberg RB. Loneliness increases the risk of type 2 diabetes: a 20 year follow-up– results from the HUNT study. Diabetologia. 2023;66(1):82–92. https://doi.org/10.1007/s00125-022-05791-6.
Google Scholar
Zhang Y, Liu M, Zhou C, et al. Social isolation, loneliness, and the risk of incident type 2 diabetes mellitus by glycemic status. Diabetes Metab. 2024;50(2):101517. https://doi.org/10.1016/j.diabet.2024.101517.
Google Scholar
Christiansen J, Larsen FB, Lasgaard M. Do stress, health behavior, and sleep mediate the association between loneliness and adverse health conditions among older people? Soc Sci Med 1982. 2016;152:80–6. https://doi.org/10.1016/j.socscimed.2016.01.020.
Google Scholar
Christiansen J, Lund R, Qualter P, Andersen CM, Pedersen SS, Lasgaard M, Loneliness. Social isolation, and chronic disease outcomes. Ann Behav Med Publ Soc Behav Med. 2021;55(3):203–15. https://doi.org/10.1093/abm/kaaa044.
Google Scholar
Zhao Y, Hu Y, Smith JP, Strauss J, Yang G. Cohort profile: the China health and retirement longitudinal study (CHARLS). Int J Epidemiol. 2014;43(1):61–8. https://doi.org/10.1093/ije/dys203.
Google Scholar
American Diabetes Association Professional Practice Committee. 2. Diagnosis and classification of diabetes: standards of care in Diabetes-2024. Diabetes Care. 2024;47(Suppl 1):S20–42. https://doi.org/10.2337/dc24-S002.
Google Scholar
Chinese Diabetes Society. Guideline for the prevention and treatment of type 2 diabetes mellitus in China (2020 edition). Chin J Diabetes. 2021;13(4):315–409. https://doi.org/10.3760/cma.j.cn115791-20210221-00095.
Google Scholar
Chinese Society of Endocrinology, Chinese Diabetes Society, Chinese Endocrinologist Association. Intervention for adults with pre–diabetes: a Chinese expert consensus (2023 edition). Chin J Diabetes. 2023;15(06):484–94. https://doi.org/10.3760/cma.j.cn115791-20230509-00188.
Google Scholar
Hughes ME, Waite LJ, Hawkley LC, Cacioppo JT. A short scale for measuring loneliness in large surveys: results from two Population-Based studies. Res Aging. 2004;26(6):655–72. https://doi.org/10.1177/0164027504268574.
Google Scholar
Kutner NG, Bliwise DL, Zhang R. Linking race and well-being within a biopsychosocial framework: variation in subjective sleep quality in two Racially diverse older adult samples. J Health Soc Behav. 2004;45(1):99–113. https://doi.org/10.1177/002214650404500107.
Google Scholar
Assari S, Sonnega A, Pepin R, Leggett A. Residual effects of restless sleep over depressive symptoms on chronic medical conditions: race by gender differences. J Racial Ethn Health Disparities. 2017;4(1):59–69. https://doi.org/10.1007/s40615-015-0202-z.
Google Scholar
Leggett A, Burgard S, Zivin K. The impact of sleep disturbance on the association between stressful life events and depressive symptoms. J Gerontol B Psychol Sci Soc Sci. 2016;71(1):118–28. https://doi.org/10.1093/geronb/gbv072.
Google Scholar
Cao Z, Li W, Wen CP, et al. Risk of death associated with reversion from prediabetes to normoglycemia and the role of modifiable risk factors. JAMA Netw Open. 2023;6(3):e234989. https://doi.org/10.1001/jamanetworkopen.2023.4989.
Google Scholar
Qiu S, Cai X, Yuan Y, et al. Muscle strength and prediabetes progression and regression in middle-aged and older adults: a prospective cohort study. J Cachexia Sarcopenia Muscle. 2022;13(2):909–18. https://doi.org/10.1002/jcsm.12905.
Google Scholar
Li H, Li C, Wang A, et al. Associations between social and intellectual activities with cognitive trajectories in Chinese middle-aged and older adults: a nationally representative cohort study. Alzheimers Res Ther. 2020;12(1):115. https://doi.org/10.1186/s13195-020-00691-6.
Google Scholar
Stevens PE, Levin A. Evaluation and management of chronic kidney disease: synopsis of the kidney disease: improving global outcomes 2012 clinical practice guideline. Ann Intern Med. 2013;158(11):825–30. https://doi.org/10.7326/0003-4819-158-11-201306040-00007.
Google Scholar
Inker LA, Schmid CH, Tighiouart H, et al. Estimating glomerular filtration rate from serum creatinine and Cystatin C. N Engl J Med. 2012;367(1):20–9. https://doi.org/10.1056/NEJMoa1114248.
Google Scholar
Chen Y, Wang C, Shang H, Yang K, Norris SL. Clinical practice guidelines in China. BMJ. 2018;360:j5158. https://doi.org/10.1136/bmj.j5158.
Google Scholar
Kim MB, Zhang Y, Chang Y, et al. Diabetes mellitus and the incidence of hearing loss: a cohort study. Int J Epidemiol. 2017;46(2):717–26. https://doi.org/10.1093/ije/dyw243.
Google Scholar
Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP). Expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult treatment panel III). JAMA. 2001;285(19):2486–97. https://doi.org/10.1001/jama.285.19.2486.
Google Scholar
Yang X, Pan A, Gong J, et al. Prospective associations between depressive symptoms and cognitive functions in middle-aged and elderly Chinese adults. J Affect Disord. 2020;263:692–7. https://doi.org/10.1016/j.jad.2019.11.048.
Google Scholar
Foti SA, Khambaty T, Birnbaum-Weitzman O, et al. Loneliness, cardiovascular disease, and diabetes prevalence in the Hispanic community health study/study of Latinos Sociocultural ancillary study. J Immigr Minor Health. 2020;22(2):345–52. https://doi.org/10.1007/s10903-019-00885-7.
Google Scholar
Kuczmarski MF, Orsega-Smith E, Evans MK, Zonderman AB. The association of loneliness with diabetes is mediated by physical activity and BMI but not diet quality. Nutrients. 2023;15(23):4923. https://doi.org/10.3390/nu15234923.
Google Scholar
Gardiner C, Geldenhuys G, Gott M. Interventions to reduce social isolation and loneliness among older people: an integrative review. Health Soc Care Community. 2018;26(2):147–57. https://doi.org/10.1111/hsc.12367.
Google Scholar
Katula JA, Dressler EV, Kittel CA, et al. Effects of a digital diabetes prevention program: an RCT. Am J Prev Med. 2022;62(4):567–77. https://doi.org/10.1016/j.amepre.2021.10.023.
Google Scholar
Papadakis A, Pfoh ER, Hu B, Liu X, Rothberg MB, Misra-Hebert AD. Shared medical appointments and prediabetes: the power of the group. Ann Fam Med. 2021;19(3):258–61. https://doi.org/10.1370/afm.2647.
Google Scholar
Heisler M, Dyer WT, Finertie H, et al. Using peer support to prevent diabetes: results of a pragmatic RCT. Am J Prev Med. 2023;65(2):239–50. https://doi.org/10.1016/j.amepre.2023.02.015.
Google Scholar
McLeod M, Stanley J, Signal V, et al. Impact of a comprehensive digital health programme on HbA(1c) and weight after 12 months for people with diabetes and prediabetes: a randomised controlled trial. Diabetologia. 2020;63(12):2559–70. https://doi.org/10.1007/s00125-020-05261-x.
Google Scholar
Díaz-Mardomingo MDC, Utrera L, Baliyan S, et al. Sex-related differences in the associations between diurnal cortisol pattern and social and emotional loneliness in older adults. Front Psychol. 2023;14:1199405. https://doi.org/10.3389/fpsyg.2023.1199405.
Google Scholar
Li H, Xia N. The role of oxidative stress in cardiovascular disease caused by social isolation and loneliness. Redox Biol. 2020;37:101585. https://doi.org/10.1016/j.redox.2020.101585.
Google Scholar
Hackett RA, Hamer M, Endrighi R, Brydon L, Steptoe A. Loneliness and stress-related inflammatory and neuroendocrine responses in older men and women. Psychoneuroendocrinology. 2012;37(11):1801–9. https://doi.org/10.1016/j.psyneuen.2012.03.016.
Google Scholar
Cole SW, Hawkley LC, Arevalo JM, Sung CY, Rose RM, Cacioppo JT. Social regulation of gene expression in human leukocytes. Genome Biol. 2007;8(9):R189. https://doi.org/10.1186/gb-2007-8-9-r189.
Google Scholar
Sharma VK, Singh TG. Chronic stress and diabetes mellitus: interwoven pathologies. Curr Diabetes Rev. 2020;16(6):546–56. https://doi.org/10.2174/1573399815666191111152248.
Google Scholar
Li W, Wang Z, Syed S, et al. Chronic social isolation signals starvation and reduces sleep in Drosophila. Nature. 2021;597(7875):239–44. https://doi.org/10.1038/s41586-021-03837-0.
Google Scholar
Qi X, Malone SK, Pei Y, Zhu Z, Wu B. Associations of social isolation and loneliness with the onset of insomnia symptoms among middle-aged and older adults in the united states: A population-based cohort study. Psychiatry Res. 2023;325:115266. https://doi.org/10.1016/j.psychres.2023.115266.
Google Scholar
Kline CE, Hall MH, Buysse DJ, Earnest CP, Church TS. Poor sleep quality is associated with insulin resistance in postmenopausal women with and without metabolic syndrome. Metab Syndr Relat Disord. 2018;16(4):183–9. https://doi.org/10.1089/met.2018.0013.
Google Scholar
Schipper SBJ, Van Veen MM, Elders PJM, et al. Sleep disorders in people with type 2 diabetes and associated health outcomes: a review of the literature. Diabetologia. 2021;64(11):2367–77. https://doi.org/10.1007/s00125-021-05541-0.
Google Scholar
Ioja S, Weir ID, Rennert NJ. Relationship between sleep disorders and the risk for developing type 2 diabetes mellitus. Postgrad Med. 2012;124(4):119–29. https://doi.org/10.3810/pgm.2012.07.2573.
Google Scholar
Wang L, Peng W, Zhao Z, et al. Prevalence and treatment of diabetes in China, 2013–2018. JAMA. 2021;326(24):2498–506. https://doi.org/10.1001/jama.2021.22208.
Google Scholar
Hanratty B, Stow D, Collingridge Moore D, Valtorta NK, Matthews F. Loneliness as a risk factor for care home admission in the english longitudinal study of ageing. Age Ageing. 2018;47(6):896–900. https://doi.org/10.1093/ageing/afy095.
Google Scholar
Yu DSF, Li PWC, Lin RSY, Kee F, Chiu A, Wu W. Effects of non-pharmacological interventions on loneliness among community-dwelling older adults: A systematic review, network meta-analysis, and meta-regression. Int J Nurs Stud. 2023;144:104524. https://doi.org/10.1016/j.ijnurstu.2023.104524.
Google Scholar