The Viking Connection to Alpha-1 Antitrypsin Deficiency

The Alpha-1 Europe Alliance created an awareness campaign unlike any other when they decided to give Vikings a starring role.

A fierce, war-painted Viking opens the 30-second spot declaring, “We are here to change history!” Cloaked in animal pelts, he stands before throngs bearing shields and ready for battle. But the sound of coughing interrupts his speech. People who have Alpha-1 often have lung and breathing problems.

The video continues: “In your veins flows what we’ve passed down to you – strength and courage – but also something that puts you in danger. Recognise the hidden signs.”

Watch the video.

The Vikings hailed from Denmark, Norway and Sweden. They were “pirates, raiders, traders and settlers on much of Britain and the European continent,” according to History.com.

Alpha-1 Antitrypsin (AAT) is a protein that protects organs from damage, according to the Alliance. In Alpha-1, or AAT Deficiency (AATD), inherited mutations lead to an abnormal AAT protein that accumulates in the liver and could cause organ damage. Too little AAT also leaves the lungs vulnerable to infections and lung problems.

In adults, signs of Alpha-1 include shortness of breath, wheezing and frequent lung infections. Liver and skin symptoms also occur. A simple blood test can diagnose the condition. The Alliance urges people to get tested, both for their own health and the health of their children, who might also have the inherited condition.

“Understanding your genetic makeup is the first step toward protecting your health,” the Alliance said on its website.

Learn more about the Nature journal article published on the Viking connection to Alpha-1.

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