Yellow Fever: How three monkey deaths sparked a critical health alert in Colombia – PAHO/WHO

July 2025


When three monkeys (a howler, a white-faced monkey, and a spider monkey) were found dead in a forested area of Colombia’s Putumayo department, what might have previously gone unnoticed became an early warning sign that triggered a swift, coordinated response to contain a yellow fever outbreak. This time, the difference was knowledge.

“Thanks to the training we received on proper sample collection in primates, we were able to detect a yellow fever outbreak after discovering three dead monkeys at the same time,” said Wilder Pérez, from the Putumayo Health Secretariat’s Vector-Borne and Zoonotic Disease Program. “Without that knowledge, the animals might have been buried without analysis — and we would have missed a critical opportunity to act.”

Credit: PAHO/WHO/Karen González Abril – “The training allowed us to detect an outbreak in time,” said Wilder Pérez, of the Putumayo Health Secretariat, applying what he learned in the first PAHO/WHO workshop on early warning signs.

Wilder had participated months earlier in a regional workshop on epizootic and vector surveillance, organized with technical support from the Pan American Health Organization (PAHO). During the training, health teams were instructed on the safe collection of samples from wildlife, vector surveillance, and intersectoral coordination.

The workshop, held in Tolima—another key department in Colombia’s current yellow fever response—proved crucial for enabling the Putumayo team to act swiftly when the first signs of the virus emerged.

En Mocoa (Putumayo), equipos de salud de más de diez territorios participaron en el Segundo Taller de Vigilancia Epizoótica y Vectorial, con el fin de fortalecer la detección y respuesta oportuna frente a la fiebre amarilla.

PAHO/WHO/Karen González Abril – In Mocoa (Putumayo), health teams from more than ten territories participated in the Second Workshop on Epizootic and Vector Surveillance, with the aim of strengthening early detection and response to yellow fever.

The training paid off. Once the dead monkeys were reported, immediate measures were taken — vaccinating environmental workers, conducting entomological studies, and analyzing the affected area. As a result, the surveillance system not only confirmed the presence of the virus, but also prevented its spread to nearby urban areas.

Tolima, in turn, is facing the most severe yellow fever outbreak recorded in the country outside the Amazon region. Since late 2024, the department has confirmed 95 human cases of yellow fever and 35 deaths. Most cases occurred in rural areas near the Galilea Forest Regional Natural Park — a dense, biodiverse jungle where humans, monkeys, and mosquito vectors coexist.

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