CRISPR Takes a Giant Leap Forward in Live Animal Gene Editing

Enveloped viruses get their outer coat by budding from cells they’ve invaded. CRISPR-Cas9 researchers coopted this behavior to produce envelope-derived vehicles that encapsulate Cas9 proteins (dark green), guide RNA and transgenes. These loaded carriers target and invade specific types of human T-cells, where they simultaneously edit and insert new genes, turning the T-cells into cancer…