Bird flu has been confirmed at a farm in Devon, the Department for Environment, Food and Rural Affairs (Defra) has said.
Defra said the case had occurred at a commercial poultry business near Tiverton on Wednesday and that all birds at the site would be humanely culled.
A 3km (1.9 mile) protection zone and 10km (6.2 mile) surveillance zone has been declared around the premises.
Anyone keeping poultry or other captive birds within the two zones must keep them housed and a record of all people who enter or leave the property, Defra said.
It comes after a case of bird flu was confirmed in poultry near Minehead and Dulverton in Somerset on Monday.
England, Scotland and Wales have been designated an avian influenza prevention zone (AIPZ) with mandatory biosecurity measures in place until further notice.
The AIPZ measures apply to all bird keepers whether they have pet or commercial birds.
Strict biosecurity is essential to protecting flocks from bird flu, Defra added.