Epel described telomeres, the protective caps at the ends of chromosomes, as particularly sensitive to stress. “Chronic stress, when we go on for years or decades without managing it, accelerates the rate of aging,” she told the podcast, warning that neglected stress management can amplify biological wear and tear.
The Brain Feels the Pressure Too
Stress is not limited to cellular changes. Neuroscientist Dr. Wendy Suzuki, Dean of NYU’s College of Arts & Science, explained on the Jay Shetty Podcast that prolonged stress damages critical areas of the brain. Elevated cortisol levels can harm the hippocampus and prefrontal cortex, key regions for memory, learning, decision-making, and attention. Suzuki cautioned that everyday digital stressors, including news and social media, are particularly harmful to younger generations.
Small Daily Habits Make a Big Difference
Fortunately, stress-related damage can be mitigated with consistent lifestyle choices. Epel recommends:
- Eating more fruits and vegetables and incorporating Omega-3-rich foods or a Mediterranean diet.
- Creating meditative breaks, even five minutes a day, to cultivate a sense of calm.
- Prioritizing deep rest with practices like yoga or breathwork.
- Keeping a mindset focused on restoring cells rather than letting stress accumulate.
Suzuki emphasized unplugging briefly from technology and engaging in real human connections. “Have a conversation with a real person—that is such a joy and privilege,” she said. Mindful gaps between waking up and interacting with digital devices can strengthen resilience and reduce anxiety.
Both experts highlight that the harmful effects of stress are not entirely permanent. Epel noted, “We can restore our cells on a daily basis, give ourselves breaks, and create an anti-inflammatory lifestyle to slow aging.” Small, consistent changes—rather than drastic overhauls—can help maintain long-term cellular and mental health.