The functional and therapeutic potential of epitranscriptomics in breast cancer

Epigenetic and epitranscriptomic dysregulation impact breast cancer development and progression. This Review article from Epigenomics explores key epitranscriptomic RNA modifications in the context of breast cancer, which may provide novel treatment avenues. Access the full article Abstract Breast cancer is one of the most commonly diagnosed malignancies worldwide and is clinically heterogenous. Breast cancer is classified into distinct histopathological and molecular subtypes that inform diagnosis, treatment, and prognosis. Although therapeutic advances, particularly targeted therapies, have improved outcomes, metastatic breast cancer remains an unmet clinical need. In addition, treatment options remain limited especially for triple negative breast cancer (TNBC). There is…

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