The silent threat: effects of PM2.5 exposure on perinatal complications and neonatal outcomes | BMC Pregnancy and Childbirth

  • Skakkebæk NE, Lindahl-Jacobsen R, Levine H, Andersson AM, Jørgensen N, Main KM, Lidegaard Ø, Priskorn L, Holmboe SA, Bräuner EV, et al. Environmental factors in declining human fertility. Nat Reviews Endocrinol. 2022;18(3):139–57.

    Article 

    Google Scholar 

  • You YA, Park S, Kwon E, Kim YA, Hur YM, Lee GI, Kim SM, Song JM, Kim MS, Kim YJ et al. Maternal PM2.5 exposure is associated with preterm birth and gestational diabetes mellitus, and mitochondrial OXPHOS dysfunction in cord blood. Environmental science and pollution research international 2024.

  • Thurston GD. Moving beyond PM2.5 mass to more effectively protect health. Am J Respir Crit Care Med 2023.

  • Kohlhepp LM, Hollerich G, Vo L, Hofmann-Kiefer K, Rehm M, Louwen F, Zacharowski K, Weber CF. [Physiological changes during pregnancy]. Anaesthesist. 2018;67(5):383–96.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Kapraun DF, Wambaugh JF, Setzer RW, Judson RS. Empirical models for anatomical and physiological changes in a human mother and fetus during pregnancy and gestation. PLoS ONE. 2019;14(5):e0215906.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Zhao L, Li T, Wang H, Fan YM, Xiao Y, Wang X, Wang S, Sun P, Wang P, Jiangcuo Z et al. Association of co-exposure to metal(loid)s during pregnancy with birth outcomes in the Tibetan plateau. Chemosphere 2023:140144.

  • Pan SC, Huang CC, Chen BY, Chin WS, Guo YL. Risk of type 2 diabetes after diagnosed gestational diabetes is enhanced by exposure to PM2.5. Int J Epidemiol 2023.

  • Coogan PF, White LF, Yu J, Burnett RT, Seto E, Brook RD, Palmer JR, Rosenberg L, Jerrett M. PM2.5 and diabetes and hypertension incidence in the black women’s health study. Epidemiol (Cambridge Mass). 2016;27(2):202–10.

    Google Scholar 

  • Koo EJ, Bae JG, Kim EJ, Cho YH. Correlation between exposure to fine particulate matter (PM2.5) during pregnancy and congenital anomalies: its surgical perspectives. J Korean Med Sci. 2021;36(38):e236.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Dai XC, Liang DT, Sun F. [PM2.5 exposure-caused damage to male reproductive function: progress in research]. Zhonghua Nan Ke Xue. 2021;27(4):361–5.

    PubMed 

    Google Scholar 

  • Zhou S, Xi Y, Chen Y, Zhang Z, Wu C, Yan W, Luo A, Wu T, Zhang J, Wu M, et al. Ovarian dysfunction induced by chronic Whole-Body PM2.5 exposure. Small. 2020;16(33):e2000845.

    Article 
    PubMed 

    Google Scholar 

  • Trusz A, Ghazal H, Piekarska K. Seasonal variability of chemical composition and mutagenic effect of organic PM2.5 pollutants collected in the urban area of Wrocław (Poland). Sci Total Environ. 2020;733:138911.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Han L, Zhou W, Pickett ST, Li W, Qian Y. Multicontaminant air pollution in Chinese cities. Bull World Health Organ. 2018;96(4):233–e242.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Magee LA, Sharma S, Nathan HL, Adetoro OO, Bellad MB, Goudar S, Macuacua SE, Mallapur A, Qureshi R, Sevene E, et al. The incidence of pregnancy hypertension in India, Pakistan, Mozambique, and Nigeria: A prospective population-level analysis. PLoS Med. 2019;16(4):e1002783.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Grover S, Brandt JS, Reddy UM, Ananth CV. Chronic hypertension, perinatal mortality and the impact of preterm delivery: a population-based study. BJOG. 2022;129(4):572–9.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Sciatti E, Orabona R. Cardiovascular prevention after hypertensive disorders of pregnancy: do not forget fetal growth restriction! J Am Coll Cardiol. 2021;78(1):91.

    Article 
    PubMed 

    Google Scholar 

  • Tita AT, Szychowski JM, Boggess K, Dugoff L, Sibai B, Lawrence K, Hughes BL, Bell J, Aagaard K, Edwards RK, et al. Treatment for mild chronic hypertension during pregnancy. N Engl J Med. 2022;386(19):1781–92.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Çintesun E, Incesu Çintesun FN, Ezveci H, Akyürek F, Çelik Ç. Systemic inflammatory response markers in preeclampsia. J Lab Physicians. 2018;10(3):316–9.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Friedman C, Dabelea D, Thomas DSK, Peel JL, Adgate JL, Magzamen S, Martenies SE, Allshouse WB, Starling AP. Exposure to ambient air pollution during pregnancy and inflammatory biomarkers in maternal and umbilical cord blood: the healthy start study. Environ Res. 2021;197:111165.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Yin J, Xia W, Li Y, Guo C, Zhang Y, Huang S, Jia Z, Zhang A. COX-2 mediates PM2.5-induced apoptosis and inflammation in vascular endothelial cells. Am J Translational Res. 2017;9(9):3967–76.

    CAS 

    Google Scholar 

  • Chen CC, Wang YR, Liu JS, Chang HY, Guo YL, Chen PC. Burden of cardiovascular disease attributable to long-term exposure to ambient PM2.5 concentration and the cost-benefit analysis for the optimal control level. Sci Total Environ 2023:164767.

  • Fujitani Y, Furuyama A, Hayashi M, Hagino H, Kajino M. Assessing oxidative stress induction ability and oxidative potential of PM(2.5) in cities in Eastern and Western Japan. Chemosphere. 2023;324:138308.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Aguilera J, Konvinse K, Lee A, Maecker H, Prunicki M, Mahalingaiah S, Sampath V, Utz PJ, Yang E, Nadeau KC. Air pollution and pregnancy. Semin Perinatol 2023:151838.

  • Chen H, Chen X, Hong X, Liu C, Huang H, Wang Q, Chen S, Chen H, Yang K, Sun Q. Maternal exposure to ambient PM(2.5) exaggerates fetal cardiovascular maldevelopment induced by homocysteine in rats. Environ Toxicol. 2017;32(3):877–89.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Agrawal A, Wenger NK. Hypertension during pregnancy. Curr Hypertens Rep. 2020;22(9):64.

    Article 
    PubMed 

    Google Scholar 

  • La Verde M, Luciano M, Fordellone M, Sampogna G, Lettieri D, Palma M, Torella D, Marrapodi MM, Di Vincenzo M, Torella M. Postpartum depression and inflammatory biomarkers of Neutrophil-Lymphocyte ratio, Platelet-Lymphocyte ratio, and Monocyte-Lymphocyte ratio: A prospective observational study. Gynecol Obstet Invest. 2024;89(2):140–9.

    Article 
    PubMed 

    Google Scholar 

  • Madendag Y, Madendag IC, Sahin E, Aydin E, Sahin ME, Acmaz G. How well do the popular ultrasonic techniques estimate amniotic fluid volume and diagnose oligohydramnios, in fact?? Ultrasound Q. 2019;35(1):35–8.

    Article 
    PubMed 

    Google Scholar 

  • Campbell AG, Miranda PY. Breastfeeding trends among very low birth weight, low birth weight, and normal birth weight infants. J Pediatr. 2018;200:71–8.

    Article 
    PubMed 

    Google Scholar 

  • Kim M, Okunowo O, Ades AM, Fuller S, Rintoul NE, Naim MY. Single-Center comparison of outcomes following cardiac surgery in low birth weight and standard birth weight neonates. J Pediatr. 2021;238:161–e167161.

    Article 
    PubMed 

    Google Scholar 

  • Edmond K. Introduction to Evidence for Global Health Care Interventions for Preterm or Low Birth Weight Infants. Pediatrics 2022, 150(Suppl 1).

  • Rumbajan JM, Yamaguchi Y, Nakabayashi K, Higashimoto K, Yatsuki H, Nishioka K, Matsuoka K, Aoki S, Toda S, Takeda S, et al. The HUS1B promoter is hypomethylated in the placentas of low-birth-weight infants. Gene. 2016;583(2):141–6.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • Nkwabong E, Kamgnia Nounemi N, Sando Z, Mbu RE, Mbede J. Risk factors and placental histopathological findings of term born low birth weight neonates. Placenta. 2015;36(2):138–41.

    Article 
    CAS 
    PubMed 

    Google Scholar 

  • O’Sharkey K, Xu Y, Cabison J, Rosales M, Yang T, Chavez T, Johnson M, Lerner D, Lurvey N, Corral CMT et al. Effects of In-Utero Personal Exposure to PM2.5 Sources and Components on Birthweight. Research square 2023.

  • Hao Y, Strosnider H, Balluz L, Qualters JR. Geographic variation in the association between ambient fine particulate matter (PM2.5) and term low birth weight in the united States. Environ Health Perspect. 2016;124(2):250–5.

    Article 
    PubMed 

    Google Scholar 

  • Sun X, Luo X, Zhao C, Zhang B, Tao J, Yang Z, Ma W, Liu T. The associations between birth weight and exposure to fine particulate matter (PM2.5) and its chemical constituents during pregnancy: A meta-analysis. Environ Pollution (Barking Essex: 1987). 2016;211:38–47.

    Article 
    CAS 

    Google Scholar 

  • Larrañaga I, Santa-Marina L, Molinuevo A, Álvarez-Pedrerol M, Fernández-Somoano A, Jimenez-Zabala A, Rebagliato M, Rodríguez-Bernal CL, Tardón A, Vrijheid M, et al. Poor mothers, unhealthy children: the transmission of health inequalities in the INMA study, Spain. Eur J Pub Health. 2019;29(3):568–74.

    Article 

    Google Scholar 

  • Continue Reading