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Trump's short list for Fed: Hassett, Warsh and Waller – Reuters
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A Brief History of Antibiotic Resistance
In the fall of 1928, Alexander Fleming returned from a holiday to his lab at St. Mary’s Hospital in London, where he was conducting experiments with staphylococcal bacteria. In an uncovered culture by an open window, he noticed mold colonies growing that seemed to be killing off the surrounding bacteria. He later determined it wasn’t the mold—a strain of Penicillium—but a “juice” it produced that killed the bacteria. He dubbed the substance penicillin.
In his petri dishes, Fleming found that penicillin could knock out the bacteria that cause diseases like scarlet fever, pneumonia, gonorrhea, meningitis, and diphtheria. But he struggled to isolate and purify the drug for clinical use.
A decade after his discovery, a team of Oxford researchers did just that, conducting experiments in mice and then, in 1941, on a British police officer covered with abscesses. The drug was astonishingly effective in just 24 hours—but the small amount of available penicillin ran out before the infection was fully treated, and the officer died a few weeks later.
Penicillin remained in short supply—so short that it was sometimes extracted from patientsʼ urine to be reused.
That changed later in 1941 when the Oxford scientists traveled to the U.S., where government scientists led a wartime effort, alongside pharmaceutical companies, to scale the drug, ultimately developing a fermentation method that dramatically expanded production.
In the late 1940s, the nascent UN and WHO pledged to spur penicillin’s global production and distribution, funding equipment and training around the world. At the same time, the drug’s growing availability spurred its overuse and misuse, an issue Fleming had anticipated.
Accepting the Nobel Prize for his discovery in 1945, he warned that “the time may come when penicillin can be bought by anyone in the shops.” He gave the example of a hypothetical Mr. X, who had a sore throat and used enough penicillin to “educate” the Streptococci to resist the drug, but not enough to kill the infection. He then passed it on to his hypothetical wife, who died from the drug-resistant infection.
“Moral: If you use penicillin, use enough,” he said.
The warning went unheeded. Penicillin became widely available in a plethora of forms. It even turned up in cosmetic creams.
But it was the golden age of antibiotic discovery, and dozens of new antibiotics emerged from the 1940s through the 1960s, including methicillin, streptomycin, chloramphenicol, erythromycin, and vancomycin. “Clinicians and patients thought that we would always be a step ahead” of the bacteria, says Scott Podolsky, MD, director of the Center for the History of Medicine at Harvardʼs Countway Library.
For a while that was true. The development of novel antibiotics largely kept pace with demand. Pharmaceutical giants were excited by antibioticsʼ promise and made significant R&D investments to get them to market.
In 1961, the first reports of methicillin-resistant Staphylococcus aureus emerged, followed in 1967 by penicillin-resistant S. pneumoniae. The list has grown over the decades.
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New Bollywood romcom sparks debate over stereotyping south India
Meryl SebastianBBC News, Kochi and
Anahita SachdevBBC News, Delhi
Maddock FilmsThe film is a love story between a woman from the southern state of Kerala and a man from Delhi in northern India A new Bollywood film has reignited an age-old conversation around how India’s largest and most influential film industry represents characters from non-Hindi speaking states.
Param Sundari, a romcom starring Sidharth Malhotra and Janhvi Kapoor, is a love story between a woman from the southern state of Kerala and a man from Delhi in northern India.
Param and Sundari first butt heads and then fall in love, successfully overcoming the cultural differences between them.
The idea isn’t new: Bollywood has long explored north-south cultural clashes through romcoms, and in a multilingual country, well-executed cross-cultural romances can be a hit.
But in this case, critics and social media users from Kerala and beyond have called out the film for its caricatured depiction of the state, particularly Sundari.
Played by Kapoor, Sundari often wears a string of jasmine flowers in her hair, can communicate with elephants and climbs coconut trees as a hobby – all stereotypical traits, often associated with Kerala. Though she’s lived there most of her life, her Malayalam is atrocious.
The criticism began as soon as the film’s trailer was shared, with many puzzling over Sundari seemingly mispronouncing her own name. This also invited comparison with another much-derided character, Shalini Unnikrishnan (played by Adah Sharma), from the controversial film The Kerala Story.
Sunshine Pictures/YouTubeThe film The Kerala Story (2023) stirred a huge controversy in India In both films, the heroines, despite living in Kerala, speak Hindi and are unable to speak fluent Malayalam when they break into it.
A few minutes into Param Sundari, when Param’s friend learns that they will be visiting a village in Kerala called Nangiarkulangara, he exaggeratedly pronounces the name and asks, “Where is that? Africa?”, combining stereotypes and casual racism into one question.
Once in Kerala, the film whizzes through a checklist of things a layperson might associate with the tourist-favourite state – its famous backwaters, the ubiquitous coconut trees, toddy, elephants, and Onam, its most popular festival.
One reviewer called the film “a feature-length ad for Kerala tourism” that “gleefully bulldozes over all possibilities of any cultural nuance”.
The film brims with coconut gags: Param and Sundari first meet by a tree, she vents her anger by furiously harvesting coconuts, and he finally confesses his love from atop one.
For many viewers, cultural inauthenticity is not a dealbreaker.
Rajiv, from northern Bihar state, saw Param Sundari as a fun window into an unfamiliar culture, saying its portrayals may not be true to life but chasing authenticity can dull entertainment.
“Maybe this will change gradually. But this much artistic freedom is okay to make the movie interesting,” he said.
For others, however, the film’s attempt to educate audiences is half-hearted.
In a blistering review, critic Sowmya Rajendran slammed the film as “generic, exhausting and offensive,” saying it hides tired cliches behind an “exotic” Kerala setting and a score that overplays the land’s “foreignness.”
AFP via Getty ImagesChennai Express (2013), starring superstars Shah Rukh Khan and Deepika Padukone, was a box office hit Films often face and survive casting criticisms: Chennai Express (2013) was panned by critics but soared at the box office.
When the makers of Mary Kom (2014) cast Priyanka Chopra to play the role of the Olympic medal-winning boxer from Manipur state, it was met with plenty of criticism. Chopra herself admitted later that “in hindsight, the part should have gone to someone from the northeast”. But the film was a hit and Chopra won awards for her spirited performance.
And Mehmood’s 1968 Padosan caricature of a Tamil singer remains a classic.
But the landscape of Indian entertainment has shifted: post-pandemic cinema closures and the rise of streaming have left Bollywood struggling for hits, with big-budget flops shaking its dominance.
Non-Hindi films now reach nationwide audiences via Netflix and Amazon Prime Video, earning fans through dubbed versions, while big Bollywood releases no longer dominate cinema primetime.
Since its release, Param Sundari has earned steadily but slowly, while the Malayalam female-superhero film Lokah has become a superhit with praise for its innovative plot and execution.
In her article on Param Sundari, writer Cris notes how many Indian film industries accept actors playing roles outside their own cultures.
“It is when the characters look like caricatures of a state or its people that the audience takes offence,” she writes.
Param Sundari does try to balance its storytelling. More than once, Sundari gets to school Param and his friend about their assumptions about her state – in one instance, throwing bias back at them about “ignorant, illiterate, arrogant, entitled” north Indians.
Courtesy Cannes Film FestivalAll We Imagine As Light (2024) made history by winning the Grand Prix at the Cannes film festival Commentators point to strong examples in India’s mobile society: Godha (2017) skilfully tells a cross-cultural romance of a Punjabi wrestler in Kerala; Axone (2019) tackles discrimination faced by people from north-eastern India with wit; Qarib Qarib Single (2017) follows a Malayali woman in Mumbai; and Cannes winner All We Imagine As Light (2024) portrays immigrant struggles with nuance.
Bollywood isn’t alone: Writer and poet Aleena notes Malayalam cinema has stereotyped tribespeople, Dalits (formerly untouchables), and Tamil characters, while Hindi speakers are often caricatured in southern films.
“I think this is a larger question of power dynamics and representation,” Aleena says, emphasising a community’s role in shaping its own stories.
She says that when a story portrays a community without including the real voices of people from the community, its risks becoming skewed and imbalanced.
“We need to make people participants or stakeholders in the art we are trying to make.”
Follow BBC News India on Instagram, YouTube, Twitter and Facebook.
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Temu hit with $2 million penalty involving reporting of stolen, counterfeit or unsafe items – PIRG
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Thunder 1st-round pick Thomas Sorber tears ACL, will miss rookie season
Thomas Sorber was drafted 15th overall in this year’s draft by Oklahoma City.
OKLAHOMA CITY (AP) — Thomas Sorber will miss the entirety of what was to be his rookie season with the NBA champion Oklahoma City Thunder, the team said Friday.
Sorber tore the ACL in his right knee on Thursday, the team said.
The 6-foot-10 center was the No. 15 pick in this year’s draft out of Georgetown. This is the second consecutive year that the Thunder have seen a first-round pick be sidelined for the entire season because of an ACL injury; it also happened last year with guard Nikola Topic, the No. 12 pick in the 2024 draft.
Sorber averaged 14.5 points and 8.5 rebounds for the Hoyas in his lone college season before turning pro.
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US dollar falls sharply – Business & Finance
NEW YORK: The US dollar fell sharply against major peers on Friday after crucial monthly jobs data showed that American employers hired fewer workers than expected, which likely guarantees a Federal Reserve interest rate cut. Labor Department data showed that nonfarm payrolls increased by only 22,000 jobs last month, far short of the 75,000 positions estimated by economists polled by Reuters.
The dollar fell across the board following the report. It weakened 0.99 percent to 147.03 against the Japanese yen, but was still on track for the second straight week of gains. The greenback dropped 0.99 percent to 0.7998 against the Swiss franc and was poised for the fourth consecutive week of losses against the currency.
“The data is giving evidence of what was feared, which is that what companies have experienced throughout the year because of changes in trading policy has added costs when it comes to tariffs,” said Juan Perez, director of trading at Monex USA in Washington. “These costs can only be absorbed for so long and what is being manifested is that companies are struggling with hiring.”
The euro was up 0.79 percent at USD1.174425 and was set to notch a weekly gain against the dollar. The dollar index fell 0.70 percent to 97.54 and was set to shed 0.23 percent this week.
US Treasury yields fell. The rate-sensitive 2-year note yield fell 11.2 basis points to 3.48 percent. The yield on benchmark US 10-year notes fell 10.4 basis points to 4.072 percent.
Wall Street’s main indexes, including the S&P 500, Nasdaq and the Dow, were all trading higher.
Traders are now pricing a 12 percent chance of a 50-basis point cut at the Fed’s next meeting later this month, while the probability of a 25-basis point cut is at nearly 88 percent, according to the CME’s FedWatch tool.
“It’s definitely not a good story for the US dollar and it’s not a good story for the United States because what today truly establishes is that we are experiencing very serious stagflation,” Perez added. The pound rose versus a weaker dollar after Friday’s news that British Deputy Prime Minister Angela Rayner resigned after admitting to underpaying property tax on a new home, in a fresh blow for her boss, Prime Minister Keir Starmer.
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Digital retail payments: FBL and OPay process record Rs100bn – Business & Finance
KARACHI: Faysal Bank Limited (FBL) and its China-based fintech partner OPay, have reached a significant milestone by processing over PKR 100 billion in digital retail payments in a remarkably short period.
This achievement reflects the success of the Bank’s forward looking and progressive approach of becoming a formidable player in the country’s digital payments space, accelerating the adoption of secure, cashless transactions.
At the milestone celebration event that took place at the Faysal Bank Head Office, senior management of both organizations were present. Speaking on the occasion, Yousaf Hussain, President and Chief Executive Officer, Faysal Bank said that Faysal Bank continues to be at the forefront with innovative solutions aimed at digitizing SME and Retail payments.
“We believe in fostering partnerships to create value in the ecosystem and enhance a collaborative framework for best results. Our successful partnership with OPay is a testament to our resolve towards creating an enabling environment which brings value for all stakeholders and end-users alike,” he added.
Present on the occasion, Zeb Khan, Chief Executive Officer, OPay (Finja) said that Opay is proud to achieve this milestone with Faysal Bank. “It reflects the strength of our partnership and the trust placed in us by merchants and consumers. Together, we will continue to drive innovation and make digital payments more accessible across Pakistan,” he added.
Copyright Business Recorder, 2025
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Uzbek GM sticks to ‘D Gukesh will lose World Chess C’ship title’ claim, brutally says…
Uzbekistan GM Nodirbek Abdusattorov recently caught everyone’s attention. In a FIDE social media video, which has gone viral, the 20-year-old predicted that D Gukesh would not be able to defend his World Championship crown next year.
D Gukesh and Nodirbek Abdusattorov during a game.(FIDE) Gukesh had his own response, as he roasted Abdusattorov. He said, “I mean, first of all, obviously, Nodirbek Abdusattorov is a great player and he’s very much capable, but (at this) the tournament he can only qualify for the Candidates, so it’s one more step to become world champion.”
“But whoever it is like, I am sure you know deserves to be there and is very much capable of playing well. I am not really rooting for anybody, I just do my part as a researcher.”
Nodirbek Abdusattorov backs up on brutal D Gukesh claim
The Uzbek GM was asked about his controversial opinon on Thursday, after his first round win at the FIDE Grand Swiss 2025. When asked if he saw the video, he simply replied, “No.”
He was asked if he still believed in his opinion, he said, “Yes, for sure.”
On being asked to predict the World C’ship winner between him and the Indian GM, he said, “I mean it’s too early to predict and answer this question. Once I qualify for the Candidates, we can talk about it.”
“Every top player or strong player wants to become world champion one day, but I mean, you have to really give your best. For now, my goal is just to finish this tournament well and if I qualify, the answer will be different,” he added.
During the World Chess C’ship, Gukesh bagged three wins against two victories for Ding Liren, and nine draws in the 14 classical rounds. He clinched victory in the deciding 14th game, as Liren made a massive blunder during the endgame. The win made Gukesh the undisputed youngest-ever World Champion.
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Alcaraz could become the first man to do this at the US Open… – ATP Tour
- Alcaraz could become the first man to do this at the US Open… ATP Tour
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Kate Middleton defended by Princess Diana’s hairdresser after criticism of new blonde hair
Princess Diana’s hairdresser is coming to Kate Middleton’s defense after “evil” remarks about her blonde look surfaced.
Sam McKnight, who was the late princess’s hairdresser from 1990 until her death in 1997, shared a statement to Instagram explaining how “horrified” he is over the recent conversation about Middleton’s hair.
On Sept. 4, Middleton and her husband, Prince William, visited the Natural History Museum in London and the princess notably had a different hairstyle. Since the images surfaced, mixed reactions have been shared about Middleton’s long, blonde look.
Princess Diana’s hairdresser defended Kate Middleton’s new look.

Kate Middleton and Prince William visited the Natural History Museum on Sept. 4.
“I am shocked, horrified, dismayed and disgusted by all the nasty comments about the Princess of Wales today. A woman’s hair is very personal to her, it’s armour, defence, confidence and so much more,” McKnight wrote on Instagram.
Kate Middleton’s New Blonde Hair Might Be More Than Just A Style Choice, Expert Says

Kate Middleton donned new hair on Sept. 4.
He continued, “I cannot believe how evil and lacking in any kind of empathy are the comments, the majority made apparently by other women, attacking a vulnerable other young woman, who has no choice, by dint of who she married, and the role she took on, to bravely face the public.”
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McKnight mentioned Middleton’s cancer diagnosis and said he believes she would “rather be away from the public arena.” In March 2024, Middleton revealed that she had been diagnosed with a form of cancer.
“She has brilliantly and quietly, unselfishly represented our country, the soft power we still have as a nation. Cancer affects individuals differently, but is life-changing for everyone. So FFS LEAVE HER ALONE. SHAME ON YOU,” McKnight concluded.
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In September 2024, Middleton announced she was cancer-free, describing the nine-month ordeal as “incredibly tough” for her family, but said that it left her with “a renewed sense of hope and appreciation of life.”

Princess Diana’s hairdresser came to Kate Middleton’s defense.
In January, Middleton shared that she was in remission.
Kate appears to be taking a page from Diana’s playbook. In 1990, during a photoshoot with Vogue, McKnight asked Diana how she would like her hair styled.
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According to The Daily Mail, she replied, “What would you do if I gave you free rein?”

Sam McKnight was Princess Diana’s hairdresser from 1990 to 1997.
After McKnight suggested cutting it short into a modern crop, Princess Diana said, “Let’s do it.”
Original article source: Kate Middleton defended by Princess Diana’s hairdresser after criticism of new blonde hair
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