Heart failure patients are being sought by Walsall researchers to take part in a trial to test a new device aimed at preventing deterioration and helping them avoid hospital admission.
The ME-HF trial, working alongside Heartfelt…

Heart failure patients are being sought by Walsall researchers to take part in a trial to test a new device aimed at preventing deterioration and helping them avoid hospital admission.
The ME-HF trial, working alongside Heartfelt…

BANGOR, Maine (WABI) – Maine’s own Jessica Meir will serve as the commander of NASA’s Space-X crew, set to launch next year.
The Caribou native will head the twelfth operational NASA Commercial Crew Program flight and the 20th crewed orbital…
Wu, A. M. et al. Global, regional, and national burden of bone fractures in 204 countries and territories, 1990–2019: a systematic analysis from the Global Burden of Disease Study 2019. Lancet Healthy Longevity 2(9), e580–e592. https://doi.org/10.1016/s2666-7568(21)00172-0 (2021).
Amin, S., Achenbach, S. J., Atkinson, E. J., Khosla, S. & Melton, L. J. Trends in fracture incidence: a population-based study over 20 years. J. Bone Min. Res. 29 (3), 581–589. https://doi.org/10.1002/jbmr.2072 (2014). 3rd.
Wennergren, D. et al. Epidemiology and incidence of tibia fractures in the Swedish fracture register. Injury 49 (11), 2068–2074. https://doi.org/10.1016/j.injury.2018.09.008 (2018).
Padilla-Eguiluz, N. G. & Gómez-Barrena, E. Epidemiology of long bone non-unions in Spain. Injury, 52 Suppl 4, S3-s7. (2021). https://doi.org/10.1016/j.injury.2021.02.053
Mills, L. A., Aitken, S. A. & Simpson, A. The risk of non-union per fracture: current Myths and revised figures from a population of over 4 million adults. Acta Orthop. 88 (4), 434–439. https://doi.org/10.1080/17453674.2017.1321351 (2017).
Mills, L. A. & Simpson, A. H. The relative incidence of fracture non-union in the Scottish population (5.17 million): a 5-year epidemiological study. BMJ Open. 3 (2). https://doi.org/10.1136/bmjopen-2012-002276 (2013).
Zura, R. et al. Epidemiology of fracture nonunion in 18 human bones. JAMA Surg. 151 (11), e162775. https://doi.org/10.1001/jamasurg.2016.2775 (2016).
Calori, G. M., Mazza, E., Colombo, M., Ripamonti, C. & Tagliabue, L. Treatment of long bone non-unions with polytherapy: indications and clinical results. Injury 42 (6), 587–590. https://doi.org/10.1016/j.injury.2011.03.046 (2011).
Ekegren, C. L., Edwards, E. R., de Steiger, R. & Gabbe, B. J. Incidence costs and predictors of non-Union, delayed union and mal-union following long bone fracture. Int. J. Environ. Res. PublicHealth https://doi.org/10.3390/ijerph15122845 (2018).
Busse, J. W., Bhandari, M., Sprague, S., Johnson-Masotti, A. P. & Gafni, A. An economic analysis of management strategies for closed and open grade I tibial shaft fractures. Acta Orthop. 76 (5), 705–712. https://doi.org/10.1080/17453670510041808 (2005).
Hak, D. J. et al. Delayed union and nonunions: epidemiology, clinical issues, and financial aspects. Injury 45 (Suppl 2), 3–7. https://doi.org/10.1016/j.injury.2014.04.002 (2014).
Nicholson, J. A., Yapp, L. Z., Keating, J. F. & Simpson, A. Monitoring of fracture healing. Update on current and future imaging modalities to predict union. Injury 52 Suppl 2, S29–s34. https://doi.org/10.1016/j.injury.2020.08.016 (2021).
Bhandari, M. et al. Assessment of radiographic fracture healing in patients with operatively treated femoral neck fractures. J. Orthop. Trauma. 27 (9), e213–219. https://doi.org/10.1097/BOT.0b013e318282e692 (2013).
Litrenta, J. et al. Determination of radiographic healing: an assessment of consistency using RUST and modified RUST in metadiaphyseal fractures. J. Orthop. Trauma. 29 (11), 516–520. https://doi.org/10.1097/bot.0000000000000390 (2015).
Bhandari, M. et al. Radiographic union score for hip substantially improves agreement between surgeons and radiologists. BMC Musculoskelet. Disord. 14, 70. https://doi.org/10.1186/1471-2474-14-70 (2013).
Kienast, B. et al. An electronically instrumented internal fixator for the assessment of bone healing. Bone Joint Res. 5 (5), 191–197. https://doi.org/10.1302/2046-3758.55.2000611 (2016).
Windolf, M. et al. Continuous implant load monitoring to assess bone healing Status-Evidence from animal testing. Med. (Kaunas). 58 (7). https://doi.org/10.3390/medicina58070858 (2022).
Pelham, H. et al. Implantable strain sensor to monitor fracture healing with standard radiography. Sci. Rep. 7 (1), 1489. https://doi.org/10.1038/s41598-017-01009-7 (2017).
Umbrecht, F. et al. Wireless implantable passive strain sensor: design, fabrication and characterization. J. Micromech. Microeng. 20 (8). https://doi.org/10.1088/0960-1317/20/8/085005 (2010).
Rajamanthrilage, A. et al. Measuring orthopedic plate strain to track bone healing using a fluidic sensor read via plain radiography. IEEE Trans. Biomed. Eng. 69 (1), 278–285. https://doi.org/10.1109/tbme.2021.3092291 (2022).
Borchani, W., Aono, K., Lajnef, N. & Chakrabartty, S. Monitoring of postoperative bone healing using smart Trauma-Fixation device with integrated Self-Powered Piezo-Floating-Gate sensors. IEEE Trans. Biomed. Eng. 63 (7), 1463–1472. https://doi.org/10.1109/tbme.2015.2496237 (2016).
Najafzadeh, A. et al. Application of fibre Bragg grating sensors in strain monitoring and fracture recovery of human femur bone. Bioeng. (Basel). 7 (3). https://doi.org/10.3390/bioengineering7030098 (2020).
McGilvray, K. C. et al. Implantable microelectromechanical sensors for diagnostic monitoring and post-surgical prediction of bone fracture healing. J. Orthop. Res. 33 (10), 1439–1446. https://doi.org/10.1002/jor.22918 (2015).
Ledet, E. H. et al. Smart fracture plate for quantifying fracture healing: preliminary efficacy in a Biomechanical model. J. Orthop. Res. 40 (10), 2414–2420. https://doi.org/10.1002/jor.25254 (2022).
Chancharoen, P., Tangpornprasert, P., Amarase, C., Tantavisut, S. & Virulsri, C. Design of osteosynthesis plate for detecting bone union using wire natural frequency. Sci. Rep. 14 (1), 12569. https://doi.org/10.1038/s41598-024-63530-w (2024).

If you want to understand where creators are truly investing, Amazon sales data tells a pretty solid story. As 2025 comes to an end, Nikon stands out with 3 camera bodies that consistently dominate buyer demand (regarding Nikon cameras)….

The PhoneWorld Awards 2025 recognize smartphones that delivered outstanding performance, innovation, and value in Pakistan’s official smartphone market over the past year. Each device was evaluated on hardware specifications,…


Local and international gold prices declined on Wednesday, with 10 grams becoming cheaper by Rs2,143 and a tola by Rs2,500, while the 10-gram price settled at Rs391,771 and the per-tola price at Rs456,962.
The global price fell by 25 dollars to 4,346 dollars per ounce.
During 2025, however, gold became expensive by Rs158,060 per 10 grams and Rs184,362 per tola, while the global price rose by 1,732 dollars per ounce.

Google Photos’ Locked Folder was meant as the sacred refuge for your more sensitive shots, but power users are growing increasingly incensed at how stripped-down the feature still is.
What started out as a layer of privacy has hardened into…

As the year comes to an end, we’re all about letting go of grudges, right? Holding on to the past sometimes just seems silly. But not if you’re a crow! These clever black birds are the ultimate grudge-holders and not just for themselves….

SAP has announced a final five months transition period for the usage rights of its Compatibility Packs for SAP S/4HANA on premise, moving the expiration date from December 31, 2025, to the end of May 2026.
Compatibility Packs provide temporary usage rights, allowing certain classical SAP ERP functionalities to operate within SAP S/4HANA, aiming to ease the migration and maintain business continuity for customers moving from SAP ERP to SAP S/4HANA.
For most of the Compatibility Packs, the usage rights end on December 31, 2025, which has been extensively communicated to customers, partners, and user groups and is documented in SAP Note 2269324.
To counter for the fact that despite the extensive communication several customers still need some more time to manage this transition, SAP is offering this final transition period in an effort to provide customers with greater choice and flexibility.
Accompanying this extension, SAP will offer tailored programs for customers that are moving to the respective SAP cloud solutions that replace the compatibility pack functionalities. We encourage affected customers to contact their SAP representative.
Stefan Steinle is EVP and head of Customer Support & Cloud Lifecycle Management at SAP.