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  • Today’s Hurdle hints and answers for December 27, 2025

    Today’s Hurdle hints and answers for December 27, 2025

    If you like playing daily word games like Wordle, then Hurdle is a great game to add to your routine.

    There are five rounds to the game. The first round sees you trying to guess the…

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  • Weight-loss drugs come for Fluffy and Fido

    Weight-loss drugs come for Fluffy and Fido

    Unlock the Editor’s Digest for free

    The global boom in weight-loss drugs has reshaped human medicine, propelled pharmaceutical shares and redrawn expectations about chronic disease. Now drugmakers spy a new growth market in the US: portly pets.

    Americans may fret over their waistlines, but their cats and dogs are in even worse shape. An estimated 60 per cent of the country’s cats and dogs are either overweight or obese according to a 2022 survey by the Association for Pet Obesity Prevention. Diabetes — once rare in animals — is now among the most expensive chronic conditions in veterinary practice.

    This is, of course, a financial opportunity. Owners lavish extraordinary sums on their animals. Pet spending reached $183bn in 2023, nearly four times 2003 levels, data from the Federal Reserve shows. If semaglutide can shrink a human waistline, why not a feline one? A handful of firms believe that obesity medicine, which transformed human healthcare in just a few years, could become a lucrative veterinary category.

    The most ambitious of these is Okava, a San Francisco start-up testing a GLP-1 drug — exenatide — delivered not by injection but by a miniature implant. Weekly injections may be tolerable for humans motivated by vanity; persuading a family to jab a struggling cat is another matter altogether. A long-acting implant that requires only two visits a year to the vet could solve the problem neatly.

    Okava launched its first clinical trial, MEOW-1, earlier this month and hopes to eventually market the treatment for up to $200 a month. That is steep, but not outlandish in a world where “premium” pet foods cost just as much and elaborate veterinary insurance plans have become mainstream middle-class indulgences.

    Yet the path to animal-size profits is far from smooth. Okava is only in the early-stage clinical trial phase of testing the drug. Lifestyle interventions such as diet and exercise remain veterinarians’ preferred first step. And history offers caution. In 2007, Pfizer got FDA approval for Slentrol, the first prescription weight-loss drug for dogs. After Pfizer spun off its Zoetis animal-health subsidiary, the therapy was discontinued because of limited demand.

    The economics of veterinary obesity may now be shifting. Diabetes care for an animal is expensive and the process is laborious: twice-daily insulin injections, regular glucose monitoring and frequent vet visits. If GLP-1-based therapies can prevent the disease or send mild cases into remission, owners may embrace them not to discipline their pets’ diets but to avoid far greater costs later.

    For drugmakers, the appeal is less sentimental. The human obesity-drug market may one day reach saturation; pet medicine, by contrast, remains under-developed. The incentives are aligned: anxious owners, rising chronic disease and a pharmacy sector hungry for new profit pools. Pharma’s next battleground, then, may be the living-room sofa — and the overfed creature sprawled across it.

    pan.yuk@ft.com

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  • Saudi strikes UAE-backed faction in Yemen as Gulf rift deepens

    Saudi strikes UAE-backed faction in Yemen as Gulf rift deepens

    Saudi Arabia has launched air strikes against a separatist faction in Yemen that is backed by the United Arab Emirates, underscoring a deepening rift between the Gulf’s two powerhouses.

    The UAE-backed Southern Transitional Council said on…

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  • Bluejay Women’s Basketball Faces Georgetown, Sunday on truTV

    Bluejay Women’s Basketball Faces Georgetown, Sunday on truTV

    Omaha, Neb. — Learning the delicate balance of the growth of the fantastic freshman class (25 points by Ava Zediker against Seton Hall) with the steady guidance of veteran leaders like Grace Boffeli (who claimed her 1,000th career rebound…

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  • Robots, AI and ‘smart tourism’ will change how we travel

    Robots, AI and ‘smart tourism’ will change how we travel

    Mengni Fu checks in to her hotel room using her mobile phone from the backseat of a taxi. When she arrives at the hotel, she drops her luggage to one of the porter robots who delivers it to her room. She unlocks her room with a digital key on her mobile phone. Then she sits on the bed and asks the AI assistant to turn on the light, close the curtains and recommend a restaurant nearby.

    So far, Fu hasn’t interacted with a single human in the hotel. This is not the script from a sci-fi film; this is travel in China in 2025. Fu, a PhD candidate at Griffith University, is describing a recent trip to Shanghai. 

    And according to consulting firm McKinsey and Co it’s the future of travel: where technology erases “typical travel pain points such as queues, misunderstandings, or misinformation” and the human interactions that do occur are “authentic and meaningful”.

    Robotics, AI and service automation are disrupting the hospitality and tourism industry — as they are many aspects of our lives. More people are turning to AI chatbots built on large language models, like ChatGPT or Trip Advisor’s “my trips”, to plan their holidays.

    Popular destinations are using “smart tourism” to manage the flow of tourists, and companies selling earbuds offering simultaneous translation are heralding the end of the language barrier.

    The question is, will new technology simply lead to streamlined service and stress-free travel, or will it fundamentally change tourism and tourist destinations?

    The ability to find a road less travelled in the future may depend on your ability to prompt an AI assistant. (Unsplash: Steven Lewis)

    ‘Killing our business’

    The Instagram account of Guide to Lofoten is usually filled with breathtaking photographs of colourful fishing villages framed by rugged mountains. The Norwegian tour company posts spectacular, but rarely viral, content. In October, a different type of post hit a nerve: “This is how ChatGPT is killing our small local business.”

    The owners claim they’re losing income and visibility as fewer people visit their website, instead getting their information from ChatGPT which doesn’t recommend local companies like theirs. “We know we’ll have to adapt — but it still hurts to watch something you’ve been building for years collapse like a house of cards in less than a year,” the owners said on Instagram.

    Dr Marianna Sigala says there’s no question people are turning to generative AI to plan their holidays — everything from choosing a destination, comparing prices, to planning a daily itinerary. “The impact is huge. It affects consumers and when consumers are affected immediately you realise companies will have to readapt because they cannot continue doing and selling what they used to,” says the professor of marketing and director of the International Hotel School at the University of Newcastle.

    Sigala likens it to the disruptive power of the steam engine or the impact Booking.com had on online travel in the early 2000s — where average consumers gained access to the Internet and began to book their own travel.

    Travel planning using generative AI is being described as the “hyper-personalisation” of travel. Sigala says the creation of highly individualised itineraries will change how tourists travel — but its impact will depend how the tool is used. “The power of AI depends first of all on the quality and the quantity of the data that it has been trained on, and it’s being trained continuously … and secondly it depends on what you ask it,” she says. “If we ask stupid questions we get stupid answers.”

    The front of an ornate old stone building, showing a balcony window with curtains half-drawn between two pillars.

     St. Peter’s Basilica – one of the most visited places in Europe – now has a “digital twin” created with the help of AI technology.  (Reuters: Amanda Perobelli)

    The road less travelled

    From 19th century railway expansion to cheap air travel to colour TV, professor Adrien Palmer argues in The Conversation that technology has long fuelled over-tourism. Palmer believes it’s too early to tell what the impact of AI will be on travel. But he says generative AI-planned itineraries could potentially nudge tourists away from over-tourism hotspots or AI-enhanced virtual reality could vanquish the need to travel in the first place.

    Like the “digital twin” of St Peter’s Basilica – one of the most visited places in Europe – that the Vatican unveiled last year. Created with the help of AI technology which analysed and pieced together vast amounts of photographs and video, the digital twin gives anyone with internet access the chance to “visit”.

    As Sigala suggests, the ability to find a road less travelled in the future may depend on your ability to prompt an AI assistant.

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    Marketing researcher Joseph Mellors says his analysis of ChatGPT “found that it gravitates towards the most visited destinations by default”. 

    “By asking sharper questions, shifting their timing, checking footprints and seeking local voices, travellers can use AI as a tool for discovery rather than congestion,” Mellors writes in The Conversation. “Every prompt is a signal to the system about what matters.”

    AI-inspired travellers will need to be wary of hallucinations — where generative-AI chatbots produce misleading content because they create plausible statements based on patterns, which aren’t necessarily correct or real. The BBC recently reported the case of two tourists who were about to hike into the Peruvian mountains in search of a non-existent canyon served to them by AI before they were stopped by a local guide.

    a woman stands in front of an illustration of robot servers

    PhD candidate Mengni Fu is exploring how gen Z consumers and workers in China and Australia feel about the rapid technological innovation transforming the tourism sector.  (Supplied: Mengni Fu)

    ‘Something is lost, something is won’

    At popular tourist destinations, AI technology is also changing how tourist flows are managed.

    “Smart cities” use big data collected from “traffic control systems, public transport ticketing, mobile phone signals, museum ticket sales, overnight stays in hotels, even credit card companies” to understand people flow, Sigala says. “AI helps them to analyse mass amounts of data faster and in real time,” she says. “Smart cities” are turning to “smart tourism” by using destination apps to communicate back to tourists suggesting different routes, attractions and visit times to help manage hordes of visitors.

    How these and other technological advances — like live translation earbuds — change the tourist experience remains to be seen. By removing the misunderstandings, the queues, the chance to get lost, will we inadvertently remove the surprises that make tourism unique? Sigala is optimistic.

    “When I was first travelling Google Maps didn’t exist … if I reflect back, I say, ‘Bloody hell, how did I find my way with this paper map?’” she says. These days she’s not afraid of getting lost, she doesn’t lose time because she took a wrong turn, and she sees things she might once have missed. “Something is lost, but something is won.”

    Mengni Fu says despite the rapid integration of AI, robotics and automation in hospitality and tourism, service with a (human) smile will still be important.

    Her PhD is exploring how gen Z consumers and workers in China and Australia feel about the rapid technological innovation transforming the sector. Fu surveyed more than 1,000 people and says overwhelmingly people would prefer that new technologies replace certain tasks in the industry, not workers. But respondents, especially in Australia, feared for their job security.

    And while Chinese respondents were more likely to embrace new technologies — given they’re more accustomed to them — they still opted for places and services where humans collaborated with technology. “Sometimes we still need that human warmness, we still need to talk with humans,” Fu says.

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  • Jim Wyatt Answers Questions From Titans Fans Ahead of Sunday’s Game vs the Saints

    Jim Wyatt Answers Questions From Titans Fans Ahead of Sunday’s Game vs the Saints

    NASHVILLE – I hope everyone had a Merry Christmas.

    Now, it’s back to football (not that it ever went away), and the New Orleans Saints are up next for the Titans.

    Two games remain in the 2025 season.

    Let’s dive back into…

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  • Literature review on the regulatory effects of hydrogen sulfide in non

    Literature review on the regulatory effects of hydrogen sulfide in non

    Introduction

    Research Background and Significance

    Non-alcoholic fatty liver disease (NAFLD) is a manifestation of metabolic syndrome in the liver and has become one of the most common chronic liver diseases globally, with a prevalence rate as high…

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  • Prince Harry, Meghan lose key team member responsible for royal truce

    Prince Harry, Meghan lose key team member responsible for royal truce

    Prince Harry, Meghan lose important team member responsible for royal truce

    Prince Harry and Meghan have lost an important member of their team, who played an instrumental role in cracking the icy relations between…

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  • UND on the International Stage: Dec. 26, 2025

    UND on the International Stage: Dec. 26, 2025

    GRAND FORKS, N.D. – It was the first day for a pair of international competitions that featured a multitude of North Dakota flavor on…

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  • What are solar storms and the solar wind? 3 astrophysicists explain

    What are solar storms and the solar wind? 3 astrophysicists explain


    By Yeimy J. Rivera, Rosa Tatiana Niembro and Samuel Badman Hernández, and Samuel Badman

    What is meant by solar storm and solar wind? – Nihal, age 11, Amalapuram, India

    Every day on Earth, you experience weather. You feel the wind blowing and…

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