Author: admin

  • CD40 Overexpression Emerges as a Potential Biomarker for Angioimmunoblastic T-Cell Lymphoma

    CD40 Overexpression Emerges as a Potential Biomarker for Angioimmunoblastic T-Cell Lymphoma

    By Wendy LaGrego
    Posted: 12/12/2025 9:00:00 AM

    Last Updated: 12/12/2025 10:55:35 AM

    Researchers at The University of Texas MD Anderson Cancer Center have identified CD40 overexpression as a potential prognostic biomarker…

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  • week of quality 2024 training kit

    week of quality 2024 training kit

    Overview

     

    Ensuring quality of the health product ensures its safety and efficacy. Manufacturers in lowand middle-income countries (LMICs) face challenges to achieve quality in local production,
    such as the lack of an available manufacturing workforce trained in quality and understanding
    regulatory quality standards and difficulties in implementing a quality culture in the
    manufacturing facility.

    The Local Production and Assistance (LPA) Unit in the Innovation and Emerging Technologies
    Department (IET), Access to Medicines and Health Products Division (MHP), WHO, supports
    Member States (MS), particularly LMICs, to strengthen sustainable local production and
    technology transfer to improve timely, equitable access to quality, safe and effective essential
    medical products. The LPA Unit provides assistance and support to MS with an ecosystem wide and holistic approach, such as conducting ecosystem assessments for sustainable,
    quality local production, developing and implementing strategies, roadmaps and tools,
    providing comprehensive capacity building and technical assistance, including for WHO
    Prequalification (PQ)/Emergency Use Listing (EUL), and facilitating technology transfer (TT).

    To support MS to overcome challenges to locally produce quality-assured vaccines and
    biotherapeutics, medicines and in vitro diagnostics (IVDs), the LPA Unit organized a new
    global training event – Week of Quality – to complement the annual Virtual cGMP Training
    Marathons also organized by the LPA Unit. The first Week of Quality was organized from 16 to
    20 June 2023 and focused on establishing quality specifications of vaccines, medicines and
    IVDs based on WHO and other international guidelines, one of the stepping stones to
    achieve quality. The second week of quality took place from 15 April to 13 June 2024 and
    focused on exploring key aspect of regulatory compliance for Medicines, IVDs and Vaccines
    and biotherapeutics. More than 1700 vaccine and biopharmaceutical manufacturers and
    regulators attended the sessions on key aspects of vaccine and biotherapeutic
    regulatory compliance. More than 1400 pharmaceutical manufacturers and
    regulators strengthened their knowledge on quality requirements for pharmaceutical
    product development.

    And for the first time, over 1000 IVD manufacturers and
    regulators, built capacity in principles of design, quality and compliance for optimizing IVD
    product development.
    Questions raised by manufacturers and regulators in the second Week of Quality have been
    assembled in this training material with questions-and-answers (Q&A) with answers prepared
    and peer-reviewed by experts with long and rich experience in the vaccine, medicine or IVD
    industry, national regulatory authority (NRA), and other organizations. This document has
    been developed to provide manufacturers and other relevant stakeholders with a continuous
    learning resource and reference document to acquire new and fortify existing, knowledge
    and capacities to strengthen the local production of quality vaccines, medicines and IVDs.

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  • Sensors Information | AZoSensors.com – Page not found

    Sensors Information | AZoSensors.com – Page not found

    While we only use edited and approved content for Azthena
    answers, it may on occasions provide incorrect responses.
    Please confirm any data provided with the related suppliers or

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  • Airline Service Quality Performance Data – September 2025

    Airline Service Quality Performance Data – September 2025

    BTS 82-25

    The U.S. Department of Transportation (DOT) today released its Airline Service Quality Performance data compiled for the month of September 2025 for on-time performance, mishandled baggage, mishandled wheelchairs, and scooters. 
     

    For additional information and interactive charts on transportation’s role in aviation, please visit BTS’ Aviation Facts and Figures. BTS regularly updates TranStats, with both Marketing Carrier On-Time Performance (Beginning January 2018) and the Reporting Carrier On-Time Performance (1987-present).

    To receive updates from BTS directly to your email, please consider subscribing to our GovDelivery service.

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  • US approves upgrade-related sale for Pakistan F-16s

    US approves upgrade-related sale for Pakistan F-16s

    The Pakistan Air Force operates a 72 aircraft-strong F-16 fleet. The PAF and the US Air Force units (including F-16 squadrons from both air forces) resumed bilateral training exercises in February 2022. (US Air…

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  • Molecular Recognition at Opioid Modulating FF Receptor

    Molecular Recognition at Opioid Modulating FF Receptor

    This study investigates the molecular mechanisms underlying ligand recognition, subtype selectivity, and activation of neuropeptide FF receptor 1 (NPFFR1)—a Gi/o-coupled receptor that responds to endogenous RF-amide peptides (RFRP-3…

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  • what to listen to, read, see and sing along to this week

    what to listen to, read, see and sing along to this week

    This week saw the launch of the final episode of our hit podcast Jane Austen’s Paper Trail (although a bonus Q&A episode is coming in January for any Austen fans experiencing withdrawal).

    Episode six is devoted to Austen’s last novel…

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  • Why Jane Austen readers still leave letters at her graveside

    Why Jane Austen readers still leave letters at her graveside

    When Jane Austen died in July 1817, aged just 41, she was buried in Winchester Cathedral. I moved to the city in 2025. As a lecturer in English literature, I have long researched and taught Austen’s novels, so I was keen to visit her final…

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  • NASA’s moon rocket celebrates 250 years of American innovation

    America250 emblem placed on rocket boosters of Artemis II, set for lunar trip in 2026.

    NASA is marking America’s 250th year with a bold new symbol of the nation’s relentless drive to explore.

    The America250 emblem is now on the twin solid…

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  • The remarkable life of Aga Khan IV – a close friend of Queen Elizabeth II hailed the world’s most well-connected royal

    The remarkable life of Aga Khan IV – a close friend of Queen Elizabeth II hailed the world’s most well-connected royal

    For others, though, Prince Shah Karim was best known for his immense wealth. Described by Forbes magazine as one of the world’s 10 richest royals, the Aga Khan IV had an estimated net worth of over £13 billion. He owned hundreds of racehorses…

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