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  • First Living Patient Gets Gene-Edited Pig Liver

    First Living Patient Gets Gene-Edited Pig Liver

    IN A WORLD-FIRST, Chinese surgeons have transplanted a 10-gene-edited pig liver into a living human as an auxiliary graft, demonstrating that a porcine liver can support human metabolism for weeks and function as a bridge in otherwise…

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  • And Then What? The Road After “Success” in the Arts

    And Then What? The Road After “Success” in the Arts

    Alexis Clements uses Alison Bechdel’s new graphic novel “Spent” to meditate on the predicament of the creative artist today.

    Spent by Alison Bechdel. Mariner Books, 2025. 272 pages.

    IN 2021, I ATTENDED an online panel organized by Film…

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  • Space.com headlines crossword quiz for week of Nov. 24, 2025: The strange star Kepler-56 is classified as this type of star

    Space.com headlines crossword quiz for week of Nov. 24, 2025: The strange star Kepler-56 is classified as this type of star

    Every week, Space.com delivers the latest discoveries, launches, and cosmic curiosities from across the universe. From groundbreaking research aboard the International Space Station to dazzling new images from the James Webb Space Telescope, the…

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  • Patti Smith Hasn’t Lost a Beat in 50 Years and Neither Has ‘Horses’

    Patti Smith Hasn’t Lost a Beat in 50 Years and Neither Has ‘Horses’

    Into your starry eyes, baby. Patti Smith has been on tour all year, celebrating the fiftieth anniversary of Horses, her classic punk debut, released in November 1975. She brought the show to New York last week, and ripped it up at the Beacon…

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  • This AI angel investor says 2 red flags instantly tell him not to buy in. Do your investing instincts pass his test?

    This AI angel investor says 2 red flags instantly tell him not to buy in. Do your investing instincts pass his test?

    Ever wonder why some startups soar while others crash before even taking off?

    According to Carles Reina, an early backer of AI startup Eleven Labs, two instant dealbreakers will make him walk away.

    For investors, spotting red flags early can save a lot of money and headaches. For founders, knowing what not to do could mean the difference between landing that big check and walking out empty-handed.

    So what is Reina’s first red flag? A founder who can’t actually build the thing they’re pitching, since that can often mean slower growth, higher costs, and a tougher road to profitability.

    “If one of the founders is not technical, like literally cannot build products, is not a researcher or something like that, I just don’t see the value in that because they’re not going to be able to move as quickly,” he told CNBC (1).

    (He told the EU-Startups podcast that the opposite is also true: The world is full of companies that built “crazy good products” but failed on the marketing side — both are needed for success (2).)

    In the fast-paced startup world, founders who can roll up their sleeves and code, design, or engineer their products have a major edge. They can pivot faster, troubleshoot in real time, and adapt before competitors even notice a shift. It’s one thing to have the idea, but Reina believes that it’s key to look for founders who can execute.

    Just look at Eleven Labs. Co-founder Mati Staniszewski holds a first-class degree in mathematics from Imperial College London.

    “It was really interesting to see he was thinking about the problems of the entire ecosystem before even actually having any product, or before even actually talking to any real potential customer,” Reina said. His technical fluency impressed Reina so much that, after their first meeting, he was willing to jump on board as an investor.

    Reina’s second no-no is a founder diving headfirst into an overhyped, overcrowded market.

    He says when too many venture capitalists chase the same hot idea, valuations shoot through the roof, and reality can quickly get lost in the noise.

    It can often lead to a lose-lose cycle of startups scrambling to justify inflated valuations, while investors compete to offer better terms (1).

    Read More: Are you richer than you think? 5 clear signs you’re punching way above the average American

    Reina’s philosophy is simply to prioritize execution over excitement.

    If you’re thinking of investing in a new business, consider whether the owners or founders have technical depth, subject matter expertise, and a track record of actually getting products to market. Pay attention to how they talk about their product. Do they light up when they explain the “how,” or is it just a lot of hype and sales jargon?

    Reina talked about red flags, but here are some green flags for investors:

    • Hands-on founders who understand their product inside and out

    • Founders have chosen an underserved market with real pain points, not just buzzwords

    • The business is building a balanced team with members who bring complementary skills to the table

    • They’ve got signs of real traction, such as early users, working prototypes, or growing revenue

    For founders, being “investor-friendly” isn’t just about schmoozing; they have to demonstrate substance.

    The founder doesn’t need to write every line of code, but they should understand the product and be able to articulate how it works, why it’s different, and where it’s going.

    What else makes a founder appealing to investors?

    • Having the right mindset. Being a founder is risky, and most successful entrepreneurs have the passion, motivation and confidence to do things in a new way (4)

    • Knowing your tech, your customer, and your market and being able to speak to them

    • Proof of execution: Bring prototypes, traction, or early user data, and don’t inflate your numbers (5)

    • Having a solid, focused go-to-market plan. If you’re clear on how and when you’ll reach milestones, you’re sharing your journey with a potential investor and hopefully getting their buy-in

    At the end of the day, startup success involves a lot of luck, but it also takes a combination of hustle, grit, skill, strategy and timing.

    So whether you’re pitching or investing, remember: go deep, not wide. Because in the startup world, hype can fade quickly, but execution and old-fashioned hard work endure.

    We rely only on vetted sources and credible third-party reporting. For details, see our editorial ethics and guidelines.

    CNBC (1); EU-Startups podcast (2); Entrepreneur (3); TechCrunch (4); TechCrunch (5)

    This article provides information only and should not be construed as advice. It is provided without warranty of any kind.

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  • ‘We just fell into the same problems’ – Max Verstappen rues car issue in tricky Qatar Sprint

    ‘We just fell into the same problems’ – Max Verstappen rues car issue in tricky Qatar Sprint

    Max Verstappen found himself driving a lonely Sprint after an eye-catching opening lap, as the issues he faced in Friday’s running in Qatar reappeared and hindered his performance.

    The Dutchman, who has claimed a record 10 pole positions in…

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  • William Dandjinou wins back-to-back short track speed skating Crystal Globes

    William Dandjinou wins back-to-back short track speed skating Crystal Globes

    The 500m final produced a good dollop of drama with two skaters crashing out and van ’t Wout losing his footing to concede his lead.

    The initial winner, Steven Dubois of Canada, was penalised for contact with Pietro Sighel, which saw Andrew Heo

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  • Trump closes airspace ‘above and surrounding’ Venezuela | World News

    Trump closes airspace ‘above and surrounding’ Venezuela | World News

    Donald Trump says the airspace “above and surrounding” Venezuela is to be closed “in its entirety”.

    The US president made the announcement on Truth Social amid growing tensions with the government of President Nicolas Maduro.

    He…

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  • Air pollution may reduce health benefits of exercise: Study

    Air pollution may reduce health benefits of exercise: Study

    England [UK], November 29 (ANI): A new study led by researchers at University College London (UCL) shows that chronic exposure to toxic air can significantly diminish the health benefits of regular physical activity.

    The study analysed data from…

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