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  • ‘Tweaks bar FCC from hearing pleas against SC decrees’ – Dawn

    1. ‘Tweaks bar FCC from hearing pleas against SC decrees’  Dawn
    2. Debate Rises Over FCC Powers in SC Appeal Cases  Daily Times
    3. Legal ambiguity: FCC chief justice’s powers remain unregulated  The Express Tribune
    4. FCC lacks jurisdiction to hear…

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  • FCC rejects challenge to CB decision on judges’ transfer – Dawn

    1. FCC rejects challenge to CB decision on judges’ transfer  Dawn
    2. Going back in time  Dawn
    3. What the 26th and 27th amendments seek to change  The Express Tribune
    4. HRCP criticises lifetime immunity for public office holders  Business Recorder
    5. Lawyers in…

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  • Calcium-activated switch improves delivery and potency of cancer-fighting drugs

    Calcium-activated switch improves delivery and potency of cancer-fighting drugs

    Cancer-fighting antibody drugs are designed to penetrate tumor cells and release a lethal payload deep within, but too often they don’t make it that far. A new study shows how this Trojan Horse strategy works better by exploiting…

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  • Global study reveals growing use of integrative therapies in cancer care

    Global study reveals growing use of integrative therapies in cancer care

    Around the world, doctors, nurses and pharmacists are turning to evidence-based integrative approaches such as acupuncture, yoga, exercise, massage and nutrition counseling to help people with cancer manage the harsh side effects of treatment.

    New research led by the University of California, Irvine shows just how widespread that shift has become and how much work remains to make these therapies accessible to all.

    Published this month in BMC Complementary Medicine and Therapies, the study surveyed more than 300 oncology professionals from the Multinational Association of Supportive Care in Cancer and the Society for Integrative Oncology across eight regions. About 70 percent said they had used or recommended at least one integrative approach to help patients manage cancer-related symptoms such as pain, fatigue, anxiety and gastrointestinal distress.

    Despite this widespread support, nearly 80 percent of respondents said these services remain underused in cancer care. Cost, lack of insurance coverage and limited training opportunities were cited as major obstacles, particularly in parts of South Asia and sub-Saharan Africa, where access is lowest. Most patients still pay for these services out of pocket. Training opportunities were most available in North America.

    The research was led by Alexandre Chan, professor and founding chair of the Department of Clinical Pharmacy Practice at UC Irvine’s School of Pharmacy & Pharmaceutical Sciences, with major contributions from Reem Nasr, a Pharm.D. candidate who helped design and conduct the study, analyze data and prepare the publication.

    “We found that cancer professionals across the globe value these approaches not as alternatives but as essential modalities to work alongside conventional cancer care,” Chan said. “At the same time, the inequities we identified show that too many patients still face barriers to getting the support they need to heal not only physically but emotionally and spiritually.”

    The study focused specifically on managing symptoms that occur either during active treatment or after therapy through an integrated approach. It explored how supportive care including acupuncture, exercise, nutrition and mindfulness can help patients cope with physical, emotional and psychological challenges that often persist long after cancer treatment ends.

    By gathering data from clinicians in eight regions through the Multinational Association of Supportive Care in Cancer and the Society for Integrative Oncology, the study was able to create a road map for improving patient-centered care. The authors recommend expanding training programs across medical, nursing and pharmacy schools to ensure that future clinicians are equipped to safely and effectively implement integrative practices.

    The findings also highlight opportunities for healthcare organizations, educators and policymakers to develop funding mechanisms, training programs and policy frameworks that promote equitable, evidence-based supportive care for all cancer patients.

    Source:

    University of California – Irvine

    Journal reference:

    https://bmccomplementmedtherapies.biomedcentral.com/articles/10.1186/s12906-025-05157-6

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  • Amazon pushes in-house AI coding tool Kiro over competitors’, memo shows

    Amazon pushes in-house AI coding tool Kiro over competitors’, memo shows

    SAN FRANCISCO, Nov 24 (Reuters) – Amazon suggested its engineers eschew AI code generation tools from third-party companies in favor of its own, a move to bolster its proprietary Kiro service, which it released in July, according to an internal memo viewed by Reuters.

    In the memo, posted to Amazon’s internal news site, the company said, “While we continue to support existing tools in use today, we do not plan to support additional third party, AI development tools.”

    Sign up here.

    “As part of our builder community, you all play a critical role shaping these products and we use your feedback to aggressively improve them,” according to the memo.

    The guidance would seem to preclude Amazon employees from using other popular software coding tools like OpenAI’s Codex, Anthropic’s Claude Code, and those from startup Cursor.

    That is despite Amazon having invested about $8 billion into Anthropic and reaching a seven-year $38 billion deal with OpenAI to sell it cloud-computing services. Amazon has been fighting a reputation that it is trailing competitors in development of AI tools as rivals like OpenAI and Google speed ahead.

    Kiro is Amazon’s homegrown AI tool for code generation, the technique for creating websites and apps using just plain English commands. It relies in large part on versions of coding tools from Anthropic, but not specifically Claude Code.

    “To make these experiences truly exceptional, we need your help,” according to the memo, which was signed by Peter DeSantis, senior vice president of AWS utility computing, and Dave Treadwell, senior vice president of eCommerce Foundation. “We’re making Kiro our recommended AI-native development tool for Amazon.”

    The internal guidance comes on the heels of Amazon widening Kiro’s availability last week to a worldwide audience along with some new features.

    Spokespeople for Anthropic, OpenAI and Cursor did not immediately respond to requests for comment. An Amazon spokesperson confirmed the memo.

    Codex, Cursor and Claude Code have become popular ways for engineers to quickly spin up new services. Cursor, for instance, was valued at nearly $30 billion after completing a funding round earlier this month.

    In October, Amazon revised its internal guidance for OpenAI’s Codex to “Do Not Use” following a roughly six month assessment, according to a memo reviewed by Reuters. And Claude Code was briefly designated as “Do Not Use,” before that was reversed following a reporter inquiry at the time.

    Reporting by Greg Bensinger; Editing by Stephen Coates

    Our Standards: The Thomson Reuters Trust Principles., opens new tab

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  • Discovery reveals role of EGFR in resistance to KRAS inhibitors in pancreatic cancer

    Discovery reveals role of EGFR in resistance to KRAS inhibitors in pancreatic cancer

    A study led by University of Cincinnati Cancer Center researchers sheds new light on how pancreatic cancer cells resist treatment and points to potential new combination therapies to make treatments more effective.

    The research,…

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  • Cat God Ranch: Deck-Building Meets Animal Ranch Management

    Cat God Ranch: Deck-Building Meets Animal Ranch Management

    Summary

    • Out now on Xbox Series X|S and Windows PC with Xbox Play Anywhere.
    • Unique blend of deckbuilding and ranch management with over 100 animals, including prehistoric creatures.
    • Our favorite genre combining animals, terrains, and props to…

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  • Oman brings GEO orders level with 2024 as larger spacecraft regain traction

    Oman brings GEO orders level with 2024 as larger spacecraft regain traction

    TAMPA, Fla. — An order for Oman’s first geostationary communications satellite has lifted the global tally for this year to six, matching all of 2024 with a month still to go but still well below the industry’s former double-digit annual pace.

    Space Communication Technologies (SCT), Oman’s state-backed operator, announced a contract Nov. 24 with Airbus for OmanSat-1.

    The Ka-band satellite will be based on Airbus’ software-defined OneSat platform, enabling reconfigurable connectivity over the Middle East, East Africa and Asia.

    Financial details were not disclosed. The contract includes a knowledge-sharing partnership as Oman joins other Middle Eastern nations pursuing greater space sovereignty and a more diversified economy in anticipation of a post-oil future.

    “We will work hand in hand with Oman’s Space Communication Technologies to help them deliver their national satellite programme and develop their sovereign capabilities to serve their future customers,” Alain Fauré, head of space systems at Airbus, said in a statement.

    Oman hailed its entry into the space sector last year after a Chinese rocket launched OL-1, a remote-sensing optical satellite developed jointly by China and local startup Oman Lens.

    An earlier Omani satellite developed with Poland’s SatRev was lost in the failed 2023 launch of Virgin Orbit’s now-defunct LauncherOne rocket.

    SatRev has remained closely engaged with Oman since then, including developing a ground station to support the country’s expanding space ambitions.

    In February, Spain’s PLD Space also signed an agreement to launch its Miura 5 small launch vehicle from a new spaceport in Oman as soon as 2027.

    Global tally

    There have been five other commercial orders this year for communications satellites destined for geostationary orbit (GEO), Novaspace senior consultant Alix Rousseliere confirmed:

    Announced Satellite Customer Manufacturer
    February Thor-8 Space Norway Thales Alenia Space
    March JSAT-32 SKY Perfect JSAT Thales Alenia Space
    April Chungwha-1 Chunghwa Telecom Astranis
    June EchoStar-26 EchoStar Maxar Space
    September Koreasat-7 KT Sat AscendArc
    November OmanSat-1 Space Communication Technologies Airbus

    Chungwha-1 and Koreasat-7 were ordered from a new breed of GEO manufacturer producing smaller, more tailored satellites closer to the size of a dishwasher than a school bus. Half of the six commercial GEO communications satellites ordered last year were 1,000 kilograms or less.

    Still, this level of activity remains a far cry from when manufacturers routinely secured 15 to 20 large, multi-ton GEO orders annually.

    The shift reflects declining demand for TV broadcasts from space, the rise of flexible digital payloads and growing competition from broadband megaconstellations in low Earth orbit.

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  • AI and tech stocks are giving ‘early 1999’ dot-com bubble vibes. Is their rally finished?

    AI and tech stocks are giving ‘early 1999’ dot-com bubble vibes. Is their rally finished?

    By Cam Hui

    Potential Fed rate cut in December could ignite a ‘risk-on’ flame – but only for a short time

    Many investors believe AI stocks are in a bubble – how long then before it pops?

    The possibility of Fed easing and short-term technical rotation patterns raise the odds of a growth rebound.

    Is it all over for growth stocks? AI market leader Nvidia (NVDA) reported stronger-than-expected quarterly results last week, and CEO Jensen Huang characterized demand for its Blackwell chip as “off the charts.”

    The stock staged a brief reflex rally but the price faded to close in the red. The market overall adopted a risk-off tone, with market leadership showing a clear growth-to-value rotation across the board on all market-cap bands and internationally.

    So, is the AI and tech rally done? I analyzed the market through the lens of leadership rotation, and here’s what I found.

    Sector strength and weakness

    My primary tool for market leadership analysis is the RRG chart. Relative Rotation Graphs, or RRG charts, are a way of depicting the changes in leadership in different groups, such as sectors, countries or regions, or market factors.

    RRG charts are organized into four quadrants, seen in the chart below. The typical group rotation pattern occurs in a clockwise fashion. Leading groups (top right) deteriorate to weakening groups (bottom right), which then rotate to lagging groups (bottom left), which change to improving groups (top left), and finally complete the cycle by improving to leading groups (top right) again.

    A conventional RRG chart of S&P 500 SPX sectors (above) currently reveals a curious pattern – no sectors are in the top right leading quadrant. Technology had rotated from the leading to weakening quadrant. While the typical rotation pattern calls for it to eventually move to the lagging quadrant in the bottom left, its tight clockwise rotation may put it back up to the leading quadrant.

    A scan of the “improving” quadrant (below) reveals the up-and-coming sectors consisting of energy, healthcare and utilities. These are sectors with individual idiosyncratic characteristics that don’t fit into a conventional value-growth or risk-on/off narrative.

    Emerging leadership

    An analysis of improving sectors from the RRG charts shows that the three emerging leadership candidates each have their own idiosyncratic risk and return patterns.

    Utilities stocks – as measured by the Utilities Select Sector SPDR ETF XLU – bottomed in April and have been in an uptrend. The relative return chart shows a saucer-shaped bottoming pattern. Relative breadth (bottom two panels) has also been strong.

    That’s positive, right? But utilities are a hybrid AI play based in the expectation of rising electricity demand from data centers. Should the strength of utilities be interpreted as bullish for AI exposure and a growth sector or bearish because of its defensive characteristics?

    Meanwhile, healthcare stocks – as measured by the Health Care Select Sector SPDR ETF XLV – are enjoying a recovery from a multi-year capitulation and washout. The sector has rallied to test a major resistance level, though it did stage a relative breakout (second panel), which is promising. While the sector has a promising intermediate-term outlook, price action appears extended in the short run.

    Energy – measured by the Energy Select Sector SPDR ETF XLE is another sector with signs of emerging leadership. It’s been in an uneven uptrend since April and its relative return chart shows a promising saucer-shaped bottom pattern. Relative breadth has also been strong.

    However, the outlook for the energy sector depends on oil prices, which have been in a downtrend but on the verge of testing support at the $60-$62 zone.

    Follow the chart leaders

    Investors can use RRG charts for different perspectives of market behavior. The chart below analyzes factor leadership against an equal-weighted S&P 500. As the chart shows, leading and improving factors can be characterized as value and fundamentally driven factors, namely large-cap value, quality, dividend growth and low volatility.

    By contrast, the factors in the bottom half of the chart can be characterized as high-octane factors, such as price momentum, speculative growth, high-beta, IPOs and large-cap growth. Viewed against such a prism, this foreshadows a period of sloppy price action or correction for the stock market.

    For a top-down macro perspective, the chart below shows rotation analysis of selected asset classes against a U.S. 60/40 stock-bond portfolio benchmark. From that perspective, equities are weakening in all regions, with the exception of emerging-markets ex-China. U.S. equities fell from the top-right leading quadrant to the bottom-right weakening quadrant. The most prominent market leaders are commodities and gold, followed by bonds in the improving quadrant.

    That said, investors shouldn’t just accept these results without some degree of cross-asset analysis. The strength in gold (GC00) and commodities is partly attributable to recent U.S. dollar DXY weakness. As well, emerging-markets ex-China stocks have also shown an inverse correlation to dollar movements.

    Federal Reserve to the rescue?

    In addition, BCA Research pointed out that the Nasdaq COMP is highly sensitive to real interest rates. This makes the FOMC December decision an enormous wildcard in the short-term outlook for stock prices and value-growth outlook.

    Read: Crypto, the dollar, stocks and credit are telling the Fed it needs to cut, popular strategist says

    In the absence of official economic data, hawkish Fedspeak from regional Fed presidents, and indications of a divided committee from the latest FOMC minutes, the December rate decision will be a close call. But the news that New York Fed President John Williams would back another rate cut is an indication that the Fed leadership will be trying to build a consensus for a cut. As a consequence, the market-derived odds of a December cut rose to almost 70% last Friday.

    Putting this all together, a market leadership review currently shows a gradual rotation to value from growth. There’s also a move to fundamentally driven investment factors such as quality and dividend growth, and away from high-octane momentum names.

    Yet the possibility of Fed easing and short-term technical rotation patterns raise the odds of a growth-stock rebound.

    Finally, I leave you this dot-com-era bubble analog from analyst Jurrien Timmer at Fidelity Investments.

    With the exception of dislocations from Russia and LTCM (Long Term Capital Management), the current market is tracking the analog fairly well. With the caveat that the magnitude of the current returns are not as large (bottom panel), we are somewhere in early 1999. I interpret this to mean that the U.S. stock market is undergoing an AI bubble – but it’s not over just yet.

    Cam Hui writes the investment blog Humble Student of the Markets, where this report first appeared. He is a former equity portfolio manager and sell-side analyst.

    More: Why the once-invincible Nvidia can’t save the AI trade

    Also read: A Fed rate cut in December seemed doubtful. Here’s why it’s now likely to happen.

    -Cam Hui

    This content was created by MarketWatch, which is operated by Dow Jones & Co. MarketWatch is published independently from Dow Jones Newswires and The Wall Street Journal.

    (END) Dow Jones Newswires

    11-24-25 1922ET

    Copyright (c) 2025 Dow Jones & Company, Inc.

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  • 2026 Oscar Predictions for 21 Categories Ahead of Thanksgiving

    2026 Oscar Predictions for 21 Categories Ahead of Thanksgiving

    A NOTE FROM SCOTT Since our last check-in, just about every current Oscar hopeful descended on Hollywood for the Academy’s Governors Awards on Nov. 16. They ostensibly were there to celebrate honorees Tom Cruise, Dolly Parton,…

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