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  • Inflammatory biomarkers offer new insights for precision medicine in ischemic stroke

    Inflammatory biomarkers offer new insights for precision medicine in ischemic stroke

    Ischemic stroke, a leading cause of disability and mortality worldwide, is a complex cerebrovascular event with outcomes heavily influenced by the inflammatory response. This response, triggered by cerebral ischemia, plays a…

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  • Scientists reveal what triggered Santorini ‘earthquake swarm’

    Scientists reveal what triggered Santorini ‘earthquake swarm’

    The “swarm” of tens of thousands of earthquakes near the Greek island of Santorini earlier this year was triggered by molten rock pumping through an underground channel over three months, scientists have discovered.

    They used physics and…

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  • From AI enthusiasm to bubble worries in one day

    From AI enthusiasm to bubble worries in one day

    Traders work on the floor at the New York Stock Exchange (NYSE) in New York City, U.S., Nov. 20, 2025.

    Brendan McDermid | Reuters

    U.S. stocks delivered one of their sharpest mood swings in months on Thursday.

    The Nasdaq Composite ended down 2.16% after spending the morning stateside up as much as 2.6%. The wild swings from high to low (regrettably, not in the opposite direction) were also seen in the S&P 500, which lost 1.56% at the end of the day after reaching a high of 1.9%. The Dow Jones Industrial Average followed the same arc, closing 0.84% lower from an intraday rise of 1.56%.

    Nvidia led the turbulence. Shares of the AI chip darling were up as much as 5% before tumbling from that peak to finish the session down 3.2%. Plotted roughly, the movement of other AI shares, including Oracle and AMD, traced similar paths, suggesting Nvidia CEO Jensen Huang's rejection of the AI bubble narrative initially reassured investors, but their concerns couldn't be repressed for long.

    September's U.S. jobs report also added to the market's strain. Even though the data was so delayed that today's economy could look very different from what it was two months ago, the numbers were much better than expected. That further dampened expectations of a rate cut, with traders increasing their bets that U.S. Federal Reserve officials will hold interest rates in December, according to the CME FedWatch tool.

    Investors now find themselves contending with stretched valuations and one fewer rate cut on the horizon. Holiday optimism is still on the calendar, but the timeline for cheer to set in looks less generous than hoped for.

    What you need to know today

    U.S. stocks fell as AI stocks tumbled again. Major indexes closed in the red on Thursday stateside in a volatile day of trading, while Bitcoin fell to its lowest price since April. Europe's Stoxx 600 added 0.4%, with AI-related stocks such as ASML and BESI ticking up.

    Key takeaways from Nvidia's earnings. CEO Jensen Huang rejected the idea of an "AI bubble," CFO Colette Kress affirmed the company's "half a trillion" revenue forecast and said China orders during the quarter were "insignificant."

    The U.S. added 119,000 jobs in September. That's sharply higher than the Dow Jones consensus estimate of 50,000. Unemployment rose to 4.4% from 4.3% in August, the highest in almost four years.

    Ray Dalio counsels holding amid bubble. The Bridgewater founder told CNBC on Thursday "the picture is pretty clear" that we are in a bubble. But nothing is popping it just yet, and investors should still hold on to their positions.

    [PRO] A 'storm brewing' in UK investment trusts. Activist investor Boaz Weinstein thinks there are opportunities because of valuation mismatches — and has revealed two of his plays in this space.

    And finally...

    Jensen Huang, chief executive officer of Nvidia Corp., during the US-Saudi Investment Forum at the Kennedy Center in Washington, DC, U.S., on Nov. 19, 2025.

    Stefani Reynolds | Bloomberg | Getty Images

    Nvidia had a blowout quarter. But analysts warn the real AI bubble risk lies elsewhere

    While Nvidia's earnings are widely viewed as an important gauge of the AI industry's health, some analysts warn that its performance doesn't tell the whole story. 

    Analysts who spoke to CNBC drew a line in the sand between AI chip companies, such as Nvidia, and downstream players, including hyperscalers and firms building AI models. "The concern is about companies raising a lot of debt to build data centers," said Gil Luria, head of technology research at D.A. Davidson.

    — Dylan Butts


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  • C-reactive protein shows stronger accuracy for early-onset sepsis in preterm newborns

    C-reactive protein shows stronger accuracy for early-onset sepsis in preterm newborns

    Neonatal EOS, a severe bloodstream infection that strikes within the first three days of life, is a major cause of infant illness and death worldwide. Because clinical features such as poor feeding, breathing problems, or lethargy…

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  • Fire prompts evacuations at UN climate talks in Brazil, and 13 suffer smoke inhalation

    Fire prompts evacuations at UN climate talks in Brazil, and 13 suffer smoke inhalation

    BELEM, Brazil — A fire briefly spread through pavilions being used for U.N. climate talks in Brazil and prompted evacuations Thursday on the next-to-last day of the conference, and officials said 13 people were treated for smoke inhalation.

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  • Sagna explains how Arsenal can replace “rock” Gabriel as they aim to keep title race going

    Sagna explains how Arsenal can replace “rock” Gabriel as they aim to keep title race going

    Former Arsenal defender Bacary Sagna revealed how the side can deal with the absence of star defender Gabriel.

    Gabriel limped off in Brazil’s friendly win over Senegal at the Emirates Stadium on Saturday in what is a crushing blow for Arsenal boss…

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  • US and Asia stocks slide as AI jitters persist

    US and Asia stocks slide as AI jitters persist

    Danielle KayeBusiness reporter

    Reuters Traders work on the floor at the New York Stock Exchange (NYSE) in New York City, U.S., November 20, 2025. Reuters

    The three major stock indexes in the US resumed their slide on Thursday, reversing course after an early morning rally.

    A burst of solid business news in the US was supposed to calm markets, which have been in retreat in recent weeks.

    But strong sales at artificial intelligence (AI) chip giant Nvidia and the world’s largest retailer Walmart, better-than-expected hiring in September, and even a pickup in home sales have so far done little to quell investor worries.

    The three biggest US stock indexes US resumed their slide on Thursday, reversing course after an early morning rally. The S&P 500 ended the day 1.5% lower, the Dow Jones Industrial Average fell 0.8% and the Nasdaq lost more than 2%.

    Major stock markets in Asia also lost ground on Friday morning.

    In New York, shares in Nvidia, which had surged in Thursday morning trading, fell by more than 3%.

    “The reaction is noteworthy, because what should have happened, didn’t happen,” said James Stanley, a senior analyst at StoneX, referring to the sudden fade in the broader US market rally on Thursday.

    “You’ve got to ask what’s happening under the surface.”

    In Asia, Japan’s Nikkei 225 was down by nearly 2%, with technology investment giant Softbank plunging by more than 8%.

    South Korea’s Kospi was down by 3.2%. Shares in chipmaker SK Hynix fell by almost 8% and Samsung was more than 4% lower.

    Hong Kong’s Hang Seng opened around 2% lower.

    The price of Bitcoin also fell on Thursday, extending recent declines and falling below $90,000 to its lowest since April. Analysts attributed the drop to, in part, concern about AI valuations.

    Fears of an AI bubble continue to swirl, even though Nvidia’s results, which showed the chip giant powering on amid robust demand for its AI chips, briefly lifted stocks after-hours on Wednesday and early Thursday.

    Chief executive Jensen Huang dismissed concerns that AI companies are overvalued. “From our vantage point, we see something very different,” he said on a call with analysts.

    But fears on Wall Street persist, investment analysts said, despite Mr Huang’s reassurance and blockbuster results from the chip-maker, which is seen as a bellwether for the AI boom. Those fears have picked up this month.

    Speaking to the BBC this month, Alphabet chief executive Sundar Pichai warned of some “irrationality” in the current AI boom.

    Analysts with Oxford Economics said the recent technology draw-down signals “a healthy correction rather than the start of something more threatening”. Earlier this week, they warned that tech stocks might suffer from profit taking in the near term, but noted that “it’s too early to call an end to the AI investment boom”.

    At the same time, investors remain on edge about the path forward for interest rates. They are still awaiting key inflation data that had been delayed during the US government shutdown, which could inform the Federal Reserve’s pace of cuts into next year.

    The S&P 500 index is more than 4% lower so far in November, putting it on track for its worst month since March.

    Investors, Mr Stanley said, are “squaring up” as they grapple with uncertainty about the state of the economy, and whether the Fed will be forced to keep interest rates higher if inflation heats up.

    “There’s a lot of trepidation about where inflation is,” he said. “There’s a lot of opacity.”

    Thursday’s jobs report did little to offer clarity on the Fed’s upcoming decisions about interest rates, said Eric Teal, chief investment officer at Comerica Bank.

    While employers added 119,000 jobs in September – more than double what many analysts had expected – the unemployment rate ticked up from 4.3% to 4.4%, the Labor Department figures showed. The mixed data, analysts said, leaves more questions than answers about whether the Fed will cut at their next meeting in December, and into 2026.

    Mr Teal pointed to continued AI adoption and lower interest rates as two key aspects of the economic backdrop that need to remain intact in order to keep propelling stocks to new highs.

    Growing jitters about an AI bubble and inflation could inject even more volatility into financial markets beyond this month, he added.

    “When you have a market that’s priced at perfection, you need all of the external catalysts behind it to keep driving it higher,” Mr Teal said.

    “A lot of those things, over the past three weeks, have been called into question.”

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  • Prostate cancer screening trial to recruit thousands of men

    Prostate cancer screening trial to recruit thousands of men

    Fergus WalshMedical Editor

    Getty Man with grey hair lying down about to enter an MRI machine.Getty

    A major prostate cancer screening trial aimed at finding the best way to detect the disease has been launched in the UK.

    The first letters have been sent out from GPs inviting men to join the study, the biggest of…

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  • ‘Will shake up the crypto presale market’

    ‘Will shake up the crypto presale market’

    A new cryptocurrency project is running artificial intelligence computing systems on solar energy while paying investors returns from the clean electricity it generates, according to Blockchain Reporter.

    EcoYield launched its token presale…

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  • Trump Meeting With Saudi Prince Showcased Prince’s Makeover, and America’s – The New York Times

    1. Trump Meeting With Saudi Prince Showcased Prince’s Makeover, and America’s  The New York Times
    2. Accords’ expansion  Dawn
    3. Trump defends Saudi crown prince over killing of journalist as they hold talks in Washington  BBC
    4. Saudi Arabia’s Prince…

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