Category: 3. Business

Staff at one of Glasgow’s busiest cinemas are to begin strike action to protest against working conditions, wages and lack of trade union recognition.

Workers at the Vue in St Enoch’s Centre told BBC Scotland News they felt they had to act for a number of reasons, including the company not paying for employees to get transport home after late night shifts which end about 02:00.

The action is believed to the first in Scotland at a cinema and is scheduled to last until 7 January.

The cinema chain said screenings of films like Wicked For Good and Zootropolis 2 at the venue would continue as normal, with temporary staff brought in.

Members of the Unite union voted in favour of striking last month, and about 50 employees are expected to take part in the protest, including picketing the cinema.

Yusuf Kidwai, the lead convenor of the strikes, said frustration with conditions had been growing for some time at the chain.

He told BBC Scotland News: “There is a lot of turnover in hospitality, so there is not a strong union culture in the industry. That’s why it’s amazing what we have been able to do here.

“Vue has told us to complain through the proper channels but we have done that, and nothing has been done.”

Mr Kidwai, who has worked at the St Enoch cinema since autumn 2024, said workers want four things from the dispute – to be paid the real living wage, for trade unions to be recognised by Vue, for staff to have better contracted hours, and for paid transport home after late shifts.

He added: “We have screenings that go on until two or three in the morning, and that asks a lot of staff.

“The area around Argyle Street is not safe at night, and you have a lot of young students left to either walk home through unsafe areas or spend half the day’s wages on a taxi.”

A planning committee meeting at Glasgow City Council recently heard how the area around St Enoch’s often suffered anti-social behaviour.

Mr Kidwai said he believed workers trained at another Vue cinema would be brought in to replace the striking workers.

Vue is one of the biggest cinema chains in the country, and its city centre venue one of Glasgow’s largest, after the closure of Cineworld earlier this year.

Founder and chief executive Tim Richards recently said the company had returned to pre-pandemic trading levels this year.

A spokesperson for Vue said: “Our teams are at the heart of our business and are highly valued. We continue to have regular meetings and open dialogue with site team members.”

Samsung Electronics and KT Corporation (KT) announced they have successfully validated AI-based radio access network (AI-RAN) optimization technology on KT’s commercial network, confirming that stable, uninterrupted service can be delivered across a range of real-world environments. Following simulation-based verification completed in June, this marks the first successful demonstration of the technology on a live commercial network.

As user-perceived communication quality becomes a key priority for telecom operators, Samsung has been developing AI-RAN optimization technologies to meet this need.

Traditionally, the same network configuration has been applied to all user devices — such as smartphones — connected to a base station. When users move through weak-signal areas or travel at high speeds, the connection between their devices and the base station may weaken or drop.

The AI-RAN optimization technology verified by the two companies automatically applies optimal configurations for each user — rather than for the network as a whole — based on real-time wireless conditions. The system leverages AI to learn from issues tied to a user’s movement paths and usage patterns, identifying recurring trends to predict potential problems. By proactively preventing disruptions, the technology helps users avoid the connectivity issues they experienced in the past.

Samsung Research of Samsung Electronics and the Future Network Laboratory at KT Corporation conducted a field test with approximately 18,000 users in select areas of Seongnam, Gyeonggi Province, featuring varying environmental conditions. The AI-RAN technology was applied to users who had repeatedly experienced service disruptions, allowing the teams to identify recurring issue patterns and develop user-specific network configurations. The companies then compared the number of disconnections before and after applying these configurations on the commercial network. The results showed a significant drop in connection failures among users who had faced frequent disruptions, as well as a notable decrease in issues for other users in the region.

AI-RAN optimization will be essential as the industry prepares for the 6G era, when data usage is expected to surge and networks must deliver stable service across a wide range of communication environments. Because the improvement in communication quality was noticeable at the user level, this achievement is expected to be recognized as a leading example of AI-RAN technology. Moving forward, the two companies plan to expand validation across additional commercial networks and further advance 6G technology.

“This is a major milestone that shows how AI can improve user experience on real-world commercial networks,” said JinGuk Jeong, Executive Vice President and Head of the Advanced Communications Research Center, Samsung Research at Samsung Electronics. “Through close collaboration with KT, we will continue shaping and validating the next generation of AI-driven communication technologies.”

“This achievement demonstrates that AI can transform network operations around users,” said Jong-Sik Lee, Executive Vice President and Head of Future Network Laboratory at KT Corporation. “Together with Samsung, we will continue developing customized optimization technologies to deliver stable, uninterrupted service and drive core 6G capabilities that create new value for customers.”

Samsung is leading AI-driven 6G innovation through its research on AI-RAN technology, integrating advanced AI capabilities into wireless networks. The company will continue to strengthen collaboration with both domestic and global operators and partners to further enhance user experiences in next-generation communications.

By Claudia Assis

The online used-car retailer’s stock has gained more than 50% over a 12-day winning streak, and is aiming for an all-time high

The Carvana-sponsored #84 Carvana Chevrolet, driven by Jimmie Johnson, at a Nascar race in 2023. Carvana’s stock has more than doubled this year.

Carvana’s stock has caught a boost from the company’s soon-to-come inclusion in the S&P 500 index – and then some.

Shares of Carvana (CVNA) on Wednesday ended at a fresh all-time high and extended their winning streak to a 12th session, their longest run on record. The stock is up 51% over that stretch.

S&P Dow Jones Indices announced late Friday that the online used-car retailer and two other companies will join the S&P 500 SPX before the market open on Dec. 22 – leapfrogging companies such as Marvell Technology (MRVL) and Strategy (MSTR), which also were thought to be candidates for inclusion.

A place in the S&P 500 is a coveted spot for companies as it exposes their shares to a much broader range of investors, including passive funds that track the equity benchmark and actively managed funds that may have restrictions on where they can invest.

Carvana’s market cap hovered at $102 billion on Wednesday, topping the $100 billion threshold for the first time. At its 2022 low, the company had a market cap of $703 million.

Carvana is a bit of a Cinderella story: It was a struggling business in late 2022 and part of 2023, beset by a cash crisis followed by a bankruptcy-dodging deal with bondholders in July 2023.

Since then, however, the company has carved out a comfortable and lucrative space for itself. Wall Street often praises its competitive advantages and potential for market-share growth in the fragmented used-car-sales industry. And competition from the likes of Amazon.com’s (AMZN) Amazon Autos is viewed as being far off in the future, if it all.

See also: Carvana survived a debt crunch. Can it survive Amazon?

Carvana has eye-catching “car vending machines” in key cities and offers buyers a still-novel way to shop from home for a used car, without haggling. And it delivers cars to buyers, sometimes on the same day, depending on the city.

While many people may be hesitant to buy a car 100% online, more are now willing to do it – especially younger consumers, who might not be willing to negotiate prices and want the process to be as quick and painless as possible.

Carvana shares have gained 130% this year, after an advance of nearly 300% last year and an eye-popping run of 1,017% in 2023.

The company finds itself in a “Goldilocks scenario,” analysts at Deutsche Bank said in a recent note.

A meaningful portion of Carvana’s infrastructure is already in place and under capacity, and “substantial fixed operating leverage” across its network is likely to allow it to both reinvest into its “market-leading competitive moats” and also deliver margin expansion, the analysts wrote.

-Claudia Assis

This content was created by MarketWatch, which is operated by Dow Jones & Co. MarketWatch is published independently from Dow Jones Newswires and The Wall Street Journal.

  (END) Dow Jones Newswires

  12-10-25 1721ET
Copyright (c) 2025 Dow Jones & Company, Inc.

(Bloomberg) — A global equities rally spurred by the Federal Reserve’s interest-rate cut evaporated as disappointing results from Oracle Corp. weighed on tech shares and focus turned to the US central bank’s outlook for further easing next year.

Futures on Nasdaq 100 slumped as much as 1.6% while a selloff in technology stocks in Asia caused the regional equity gauge to reverse early gains. S&P 500 futures declined 1.1%. Shares of Oracle, whose fate is deeply tied to the artificial intelligence boom, plunged more than 10% in extended US trading after second-quarter cloud sales fell just short of analysts’ estimates. In a sign of waning risk appetite, Bitcoin plunged more than 3%.

The moves in Asia came after the S&P 500 rose 0.7% on Wednesday, ending just short of all-time highs as the Fed cut rates for a third consecutive time and Chair Jerome Powell voiced optimism that the economy will strengthen as the inflationary impact from tariffs fades away. The result marked the first time since 2019 that three officials voted against a policy decision, with dissents on both ends of the policy spectrum. Officials maintained their outlook for a single cut in 2026.

“While most of the focus was on the FOMC, a key risk for markets overnight was Oracle,” said Billy Leung, investment strategist at Global X Management. Its result was a key test for the AI infrastructure trade given Oracle’s role as a bellwether for hyperscale data center spending and has added to broader tech pressure, he said.

A gauge of Asian technology stocks was down more than 1%, versus a 0.4% decline in the broader regional benchmark.

Traders in Asia were also assessing the market impact of Mexican lawmakers’ final approval for new tariffs on the region’s imports. Also in focus was Thursday’s interest-rate decision in the Philippines, where the central bank is predicted to cut its key interest rate for a fifth straight meeting.

In Japan, bond futures extended gains after an auction of 20-year government debt drew its strongest demand since 2020 as higher yield levels attracted investors. Yields across the curve have climbed to multi-year highs on renewed fiscal concerns as well as rising expectations for a Bank of Japan rate hike at its meeting next week.

Elsewhere in markets, a gauge of the dollar edged higher after falling 0.4% on Wednesday. In commodities, oil prices were in focus after the US seized a sanctioned tanker off Venezuela, deterring more shipments from the South American producer and raising the risk of a conflict.

‘Fairly Choppy’

US Treasuries rallied on Wednesday, with the policy-sensitive two-year yield sliding eight basis points, as the Fed’s quarter-point rate reduction was accompanied by the authorization of fresh Treasury bill purchases to rebuild bank reserves. The yield fell one more basis point on Thursday.

The 10-year yield, which dropped around four basis points in the previous session, was three basis points lower on Thursday. The declines have stalled a prior run up in yields that had driven one global gauge to its highest since 2009.

Powell pushed through the quarter percentage point cut not only over the objection of a few voters. A much larger group of regional Fed bank presidents who participated in the debate but weren’t among this year’s voting roster also signaled they opposed the cut.

The fractures could foreshadow what’s to come in 2026, when a new chair may struggle even more than Powell to marshal consensus at the Fed.

The Fed chair suggested the central bank had now acted sufficiently to help stabilize the labor market while leaving rates high enough to continue weighing on price pressures. He also underscored the importance of upcoming economic reports while advising caution on assessing household jobs readouts, given technical distortions after a government shutdown caused a data blackout.

Nick Twidale, chief analyst at AT Global Markets in Sydney, said he is “hesitant” on how much momentum the Fed’s cut will bring to global markets.

“The forward guidance was probably less dovish than most investors were hoping for,” he said. “We may see some fairly choppy markets in the sessions ahead as the market digests what Jerome Powell had to say.”

Corporate News

Private equity firm TPG Inc. is considering options for APM Monaco, including a possible stake sale or an initial public offering of the jeweler, according to people familiar with the matter. SK Hynix Inc. fell after South Korea’s main bourse issued a higher-level warning on investing in the stock following strong gains sparked by expectations of a listing in New York. Investment banks are on track to take home their smallest slice of underwriting fees from Hong Kong listings in years, even as share sales in the city have staged a blistering rebound. President Donald Trump signaled he’ll oppose a Warner Bros. Discovery Inc. deal that doesn’t include new ownership of CNN, a potential wrinkle for the bid from Netflix Inc. Shares of Jingdong Industrials Inc., the supply-chain unit of Chinese e-commerce giant JD.com Inc., fell in their Hong Kong trading debut after a HK$2.98 billion ($383 million) initial public offering. Japan’s stock market is witnessing a record wave of large private transactions known as block trades, stemming from companies reducing cross-shareholdings to improve corporate governance. Chinese artificial intelligence startup DeepSeek has relied on Nvidia Corp. chips that are banned in the country to develop an upcoming AI model, according to a new report in The Information. Coca-Cola Co. said Chief Executive Officer James Quincey is stepping down and will be replaced at the end of March by Henrique Braun, the company’s chief operating officer. Some of the main moves in markets:

Stocks

S&P 500 futures fell 0.8% as of 12:49 p.m. Tokyo time Japan’s Topix fell 0.7% Australia’s S&P/ASX 200 rose 0.2% Hong Kong’s Hang Seng was little changed The Shanghai Composite fell 0.5% Euro Stoxx 50 futures were little changed Currencies

The Bloomberg Dollar Spot Index was little changed The euro was little changed at $1.1694 The Japanese yen rose 0.2% to 155.69 per dollar The offshore yuan was little changed at 7.0611 per dollar Cryptocurrencies

Bitcoin fell 2.7% to $89,920.79 Ether fell 4.5% to $3,189.12 Bonds

The yield on 10-year Treasuries declined three basis points to 4.12% Australia’s 10-year yield declined 12 basis points to 4.69% Commodities

West Texas Intermediate crude was little changed Spot gold fell 0.2% to $4,218.59 an ounce This story was produced with the assistance of Bloomberg Automation.

–With assistance from Richard Henderson.

©2025 Bloomberg L.P.

Quincey to Continue as Executive Chairman of the Board

ATLANTA–(BUSINESS WIRE)–
The Coca-Cola Company today announced that its board of directors has elected Executive Vice President and Chief Operating Officer Henrique Braun as CEO, effective March 31, 2026. Braun will succeed James Quincey, who will transition to Executive Chairman after serving as CEO for nine years.

The board also plans to nominate Braun, 57, to stand for election as a director at the company’s 2026 Annual Meeting of Shareowners.

Leadership transition

Quincey, 60, will step down as CEO after a highly successful tenure. He has led the transformation of the business as a total beverage company, driven by a focus on staying closely connected to consumers. Under his leadership, the company has added more than 10 additional billion-dollar brands.

Quincey has reshaped the company’s strategy and operating model to create a more agile, networked company, including a focus on digital transformation and modernized marketing. He also led the company through the COVID-19 pandemic.

As CEO, Braun will focus on opportunities to build on this strong foundation. His priorities include seeking the best growth opportunities worldwide; driving the company to get even closer to consumer needs; and leveraging technology as an enabler of business performance and growth.

“James Quincey is a transformative leader,” said David Weinberg, Coca-Cola’s lead independent director. “James set and executed a strategy that has built Coca-Cola’s status as a global leader. James will continue to be very active in the business through his role as Executive Chairman. We are confident that Henrique Braun will build on the company’s existing strengths to unlock more growth opportunities and increase the power of the incredible Coca-Cola system.”

About Henrique Braun

Braun has served as EVP and COO since Jan. 1, 2025, overseeing all the company’s operating units worldwide. He has served as EVP since 2024. From 2023 to 2024, Braun served as Senior Vice President and President, International Development, overseeing seven of the company’s nine operating units.

Prior to that, Braun served as President of the Latin America operating unit from 2020 to 2022 and as President of the Brazil business unit from 2016 to 2020. From 2013 to 2016, Braun was President for Greater China & South Korea.

Braun joined Coca‑Cola in 1996 in Atlanta and progressed through roles of increasing responsibilities in North America, Europe, Latin America and Asia. Those positions included supply chain, new business development, marketing, innovation, general management and bottling operations.

He holds a bachelor’s degree in agricultural engineering from the University Federal of Rio de Janeiro, a Master of Science degree from Michigan State University and an MBA from Georgia State University. Braun is an American citizen who was born in California and raised in Brazil.

“I’m honored to take on this new role and have tremendous appreciation for everything James has done to lead the company,” Braun said. “I will focus on continuing the momentum we’ve built with our system. We’ll work to unlock future growth in partnership with our bottlers. I’m excited about the future of our business and see huge opportunities in a fast-changing global market.”

About James Quincey

Quincey became CEO in 2017 and Chairman of the board in 2019. He joined the company in 1996 and has held leadership roles around the world.

Before becoming CEO, Quincey served as COO from 2015 to 2017 and as President from 2015 to 2018. From 2013 to 2015, he was President of the company’s Europe Group. Under his leadership, the group expanded its brand portfolio and improved market share. Quincey also played a key role in the creation of Coca‑Cola Europacific Partners, one of the largest independent Coca-Cola bottlers in the world. Quincey served as President of the Northwest Europe and Nordics business unit from 2008 to 2012.

Quincey joined the company in Atlanta in 1996 as director of learning strategy for the Latin America Group. He went on to serve in a series of operational roles in Latin America, eventually leading to his appointment as President of the South Latin division in 2003.

He was President of the company’s Mexico division from 2005 to 2008. Prior to joining Coca-Cola, Quincey was a partner in strategy consulting at The Kalchas Group, a spinoff of Bain & Company and McKinsey.

Quincey is a director of Pfizer Inc. and a board member of The Consumer Goods Forum. He is a founding member of the New York Stock Exchange Board Advisory Council.

Quincey received a bachelor’s degree in electronic engineering from the University of Liverpool. He is a native of Britain.

“I’m stepping down as CEO after a 30-year career with the company, and I have an appreciation of what a privilege it has been to serve this great and enduring business,” Quincey said. “Henrique is a trusted and highly experienced business partner, and he’s the right leader to steer the company and the Coca-Cola system for future growth and success.”

Weinberg said the company is looking forward to a seamless transition in management.

“On behalf of the board, I thank James for his outstanding leadership,” Weinberg said. “James has done what a strong CEO should do – he has focused on the future and developing and empowering the next set of leaders who will take Coke forward. Henrique has shown that he is the right leader for the future of Coca-Cola.”

About The Coca-Cola Company

The Coca-Cola Company (NYSE: KO) is a total beverage company with products sold in more than 200 countries and territories. Our company’s purpose is to refresh the world and make a difference. We sell multiple billion-dollar brands across several beverage categories worldwide. Our portfolio of sparkling soft drink brands includes Coca-Cola, Sprite and Fanta. Our water, sports, coffee and tea brands include Dasani, smartwater, vitaminwater, Topo Chico, BODYARMOR, Powerade, Costa, Georgia, Fuze Tea, Gold Peak and Ayataka. Our juice, value-added dairy and plant-based beverage brands include Minute Maid, Simply, innocent, Del Valle, fairlife and AdeS. We’re constantly transforming our portfolio, from reducing sugar in our drinks to bringing innovative new products to market. We seek to positively impact people’s lives, communities and the planet through water replenishment, packaging recycling, sustainable sourcing practices and carbon emissions reductions across our value chain. Together with our bottling partners, we employ more than 700,000 people, helping bring economic opportunity to local communities worldwide. Learn more at www.coca-colacompany.com and follow us on Instagram, Facebook and LinkedIn.

Forward-Looking Statements

This press release may contain statements, estimates or projections that constitute “forward-looking statements” as defined under U.S. federal securities laws. Generally, the words “believe,” “opportunity,” “ahead,” “expect,” “intend,” “estimate,” “anticipate,” “project,” “will” and similar expressions identify forward-looking statements, which generally are not historical in nature. Forward-looking statements are subject to certain risks and uncertainties that could cause The Coca-Cola Company’s actual results to differ materially from its historical experience and our present expectations or projections. These risks include, but are not limited to, unfavorable economic and geopolitical conditions, including the direct or indirect negative impacts of the conflict between Russia and Ukraine and conflicts in the Middle East; increased competition; an inability to be successful in our innovation activities; changes in the retail landscape or the loss of key retail or foodservice customers; an inability to expand our business in emerging and developing markets; an inability to successfully manage the potential negative consequences of our productivity initiatives; an inability to attract or retain specialized or top talent with perspectives, experiences and backgrounds that reflect the broad range of consumers and markets we serve around the world; disruption of our supply chain, including increased commodity, raw material, packaging, energy, transportation and other input costs; an inability to successfully integrate and manage our acquired businesses, brands or bottling operations or an inability to realize a significant portion of the anticipated benefits of our joint ventures or strategic relationships; failure by our third-party service providers and business partners to satisfactorily fulfill their commitments and responsibilities; an inability to renew collective bargaining agreements on satisfactory terms, or we or our bottling partners experience strikes, work stoppages, labor shortages or labor unrest; obesity and other health-related concerns; evolving consumer product and shopping preferences; product safety and quality concerns; perceived negative health consequences of processing and of certain ingredients, such as non-nutritive sweeteners, color additives and biotechnology-derived substances, and of other substances present in our beverage products or packaging materials; failure to digitalize the Coca-Cola system; damage to our brand image, corporate reputation and social license to operate from negative publicity, whether or not warranted, concerning product safety or quality, workplace and human rights, obesity or other issues; an inability to successfully manage new product launches; an inability to maintain good relationships with our bottling partners; deterioration in our bottling partners’ financial condition; an inability to successfully manage our refranchising activities; increases in income tax rates, changes in income tax laws or the unfavorable resolution of tax matters, including the outcome of our ongoing tax dispute or any related disputes with the U.S. Internal Revenue Service (“IRS”); the possibility that the assumptions used to calculate our estimated aggregate incremental tax and interest liability related to the potential unfavorable outcome of the ongoing tax dispute with the IRS could significantly change; increased or new indirect taxes; changes in laws and regulations relating to beverage containers and packaging; significant additional labeling or warning requirements or limitations on the marketing or sale of our products; litigation or legal proceedings; conducting business in markets with high-risk legal compliance environments; failure to adequately protect, or disputes relating to, trademarks, formulas and other intellectual property rights; changes in, or failure to comply with, the laws and regulations applicable to our products or our business operations; fluctuations in foreign currency exchange rates; interest rate increases; an inability to achieve our overall long-term growth objectives; default by or failure of one or more of our counterparty financial institutions; impairment charges; an inability to protect our information systems against service interruption, misappropriation of data or cybersecurity incidents; failure to comply with privacy and data protection laws; evolving sustainability regulatory requirements and expectations; increasing concerns about the environmental impact of plastic bottles and other packaging materials; water scarcity and poor quality; increased demand for food products, decreased agricultural productivity and increased regulation of ingredient sourcing due diligence; climate change and legal or regulatory responses thereto; adverse weather conditions; and other risks discussed in our filings with the Securities and Exchange Commission (“SEC”), including our Annual Report on Form 10-K for the year ended December 31, 2024, and subsequently filed Quarterly Report on Form 10-Q, which are available from the SEC. You should not place undue reliance on forward-looking statements, which speak only as of the date they are made. We undertake no obligation to publicly update or revise any forward-looking statements.

Investors and Analysts: Robin Halpern, koinvestorrelations@coca-cola.com

Media: Scott Leith, sleith@coca-cola.com

Source: The Coca-Cola Company

Released December 10, 2025

Emerging technology research dominates the Energy Department’s coming scientific agenda, with agency leadership moving in sync with the Trump administration’s larger goal of ensuring the U.S. wins the global race to artificial intelligence dominance.

Darío Gil, Energy’s undersecretary for science, testified before the House Science, Space and Technology Committee on the agency’s technological priorities — most notably the new Genesis Mission unveiled by President Doanld Trump last month. 

“This mission, which we envision as our generation’s Manhattan or Apollo scale project, will multiply the return on taxpayer investment and solidify America’s global technological and strategic leadership,” Gil said. 

In addition to clarifying the Genesis Mission’s role as an “integrated discovery platform” that will marry national laboratories, academia and industry partners to deliver new AI applications, Gil unveiled the first investment installment of $320 million for the American Science Cloud and the Transformational Model Consortia. 

These two initiatives, which were both created from the One Big Beautiful Bill Act, will further help disperse funding to Energy’s national laboratory network to begin curating data sets to train new scientific AI models.  

“At the core, we’re doing two things: we’re building a platform, and we are constructing a portfolio of scientific and engineering challenges for energy, national security and discovery science,” Gil said. 

Although Genesis is primarily focused on developing new and experimental AI applications and running them on the nation’s network of high-performance supercomputers, Gil also shared other emerging tech sectors that Energy is prioritizing and aiming to incorporate into the Genesis infrastructure.

Quantum computing is among the top fields to be eventually incorporated into the AI and supercomputing infrastructure Energy is scaling. Gil, who previously oversaw IBM’s scientific research portfolio that included multiple quantum information science and technology assets, testified that the convergence of AI and quantum computing will serve as “a scientific and technological revolution.”

This perspective will provide an opportunity to merge more advanced AI models with relatively immature quantum computing systems.

“We recognize that AI and quantum are not just tools, but foundational elements of new supercomputing platforms,” Gil said. “AI and quantum computing offer a fundamentally new paradigm for understanding the natural world. They are the new scientific instruments of our time. And just like telescopes and microscopes transform how we see the very large, the very far and the very small, AI and quantum supercomputers are going to transform how we make sense of the very complex.”

Gil also vocalized support for the National Quantum Initiative Act Reauthorization, a landmark appropriations bill specifically for quantum information sciences that has stalled in Congress since its lapse in 2023. 

Beyond quantum computing and AI, Gil said accelerating scalability of nuclear and fusion development is another top policy priority for Energy. He added that following Energy’s release of a formal roadmap to developing commercial fusion power in October, the department is working with private sector and academic stakeholders on a holistic look at what the U.S. needs to do to scale fusion power plants in the early 2030s.

Emerging technology research dominates the Energy Department’s coming scientific agenda, with agency leadership moving in sync with the Trump administration’s larger goal of ensuring the U.S. wins the global race to artificial intelligence dominance.

Darío Gil, Energy’s undersecretary for science, testified before the House Science, Space and Technology Committee on the agency’s technological priorities — most notably the new Genesis Mission unveiled by President Doanld Trump last month. 

“This mission, which we envision as our generation’s Manhattan or Apollo scale project, will multiply the return on taxpayer investment and solidify America’s global technological and strategic leadership,” Gil said. 

In addition to clarifying the Genesis Mission’s role as an “integrated discovery platform” that will marry national laboratories, academia and industry partners to deliver new AI applications, Gil unveiled the first investment installment of $320 million for the American Science Cloud and the Transformational Model Consortia. 

These two initiatives, which were both created from the One Big Beautiful Bill Act, will further help disperse funding to Energy’s national laboratory network to begin curating data sets to train new scientific AI models.  

“At the core, we’re doing two things: we’re building a platform, and we are constructing a portfolio of scientific and engineering challenges for energy, national security and discovery science,” Gil said. 

Although Genesis is primarily focused on developing new and experimental AI applications and running them on the nation’s network of high-performance supercomputers, Gil also shared other emerging tech sectors that Energy is prioritizing and aiming to incorporate into the Genesis infrastructure.

Quantum computing is among the top fields to be eventually incorporated into the AI and supercomputing infrastructure Energy is scaling. Gil, who previously oversaw IBM’s scientific research portfolio that included multiple quantum information science and technology assets, testified that the convergence of AI and quantum computing will serve as “a scientific and technological revolution.”

This perspective will provide an opportunity to merge more advanced AI models with relatively immature quantum computing systems.

“We recognize that AI and quantum are not just tools, but foundational elements of new supercomputing platforms,” Gil said. “AI and quantum computing offer a fundamentally new paradigm for understanding the natural world. They are the new scientific instruments of our time. And just like telescopes and microscopes transform how we see the very large, the very far and the very small, AI and quantum supercomputers are going to transform how we make sense of the very complex.”

Gil also vocalized support for the National Quantum Initiative Act Reauthorization, a landmark appropriations bill specifically for quantum information sciences that has stalled in Congress since its lapse in 2023. 

Beyond quantum computing and AI, Gil said accelerating scalability of nuclear and fusion development is another top policy priority for Energy. He added that following Energy’s release of a formal roadmap to developing commercial fusion power in October, the department is working with private sector and academic stakeholders on a holistic look at what the U.S. needs to do to scale fusion power plants in the early 2030s.

Introduction

Health care systems are facing growing pressures due to an aging population, multiple long-term conditions, and rising levels of frailty []. To address these challenges, innovative solutions that enhance productivity are essential [-]. In the United Kingdom, a paradigm shift is being promoted [,], emphasizing “predict and prevent” care, transitioning from “analog to digital” and delivering care closer to home [-,]. One potential solution is hospital-at-home (HaH) services, sometimes called virtual wards [], which deliver hospital-level care in a patient’s place of residence. These services aim to avoid hospital admissions or facilitate early discharge, demonstrably improving patient satisfaction, improving outcomes, and reducing admissions to hospital and residential care [-]. One area of use is for patients with frailty, who are at increased risk of functional decline and mortality [,]. The dynamic nature of frailty [,] underscores the need for timely detection, personalized care, and home-based interventions to support recovery.

In the United Kingdom, national guidance advocates the integration of digital technology to optimize service delivery []. National priorities have promoted significant investment in a ”tilt towards technology“ [], with the UK public sector spending £26 billion annually on digital technology [,]. The revolution of Healthcare 4.0 [-] highlights the transformative potential of advanced technologies in a digitally connected world, especially in home-based care [-]. These technologies can empower patient self-monitoring; enhance clinical decision-making; and optimize resources, costs, and safety [].

Reviews exploring technology in HaH care categorize these as low-intensity (eg, telephone or teleconferencing), high-intensity (eg, apps or wearables) [], manual, or automated remote monitoring []. Evidence on how to fully harness these technologies to optimize clinical decision-making, enhance risk prediction, and personalize care is limited.

An emerging approach in health care is digital twin (DT) technology, which creates a dynamic virtual representation of a patient or health care system leveraging real-time data. DT aims to closely mirror the real-world counterpart, analyzing its parameters using sophisticated methods like machine learning (ML) for dynamic simulation and predictive capabilities []. These methods can aid timely decision-making. With a patient DT, clinicians can visualize current states and forecast future scenarios, such as deterioration, early risk identification, timely intervention, optimization of care, and resource allocation. This supports proactive rather than reactive health care. To develop a DT, collaboration is required across disciplines, including engineering, medicine, computing, and data science, to understand the required data and enabling technologies within the 5 DT architectural layers: sensing (capturing information), communication, storage, analytics, and visualization [-].

The potential of DT in health care is increasingly recognized—leveraging artificial intelligence (AI), Internet of Things (IoT), big data, and predictive analytics—to anticipate health risks, support early disease detection, and enhance operational efficiency []. DTs can simulate disease progression, enabling proactive, personalized treatment and outcome prediction [,]. Examples include electrocardiogram (ECG)-based heart rhythm classifiers to detect heart problems [], drug interaction modeling to predict medication responses [], and dynamic glucose monitoring for medication adjustment in diabetes [,]. DTs have shown promise in personalized medicine, hospital management, and surgery [,,].

However, challenges remain, with existing literature presenting various definitions of DT architectures [,,,]. Although this gives us valuable insight, the lack of clarity and consistency in frameworks for DT health care applications can make it difficult for implementation and evaluation []. This review aimed to address the knowledge gap linking DT architecture with HaH care for patients with frailty, considering the complexity and acuity of this patient cohort. To our knowledge, no literature currently addresses the application of DTs in this context.

This review aimed to identify existing evidence supporting the development of DTs for HaH care for patients with frailty, addressing the following research questions:

1. What DT-enabling tools have been applied in home-based care for patients with frailty, and how can they be systematically categorized?
2. How are data collected, recorded, and transmitted (sensing, communication, and storage)?
3. What outcomes are evaluated, and how are the results being used to inform care (analytics/decision-making, visualization)?
4. Are the tools evaluated for effectiveness and, if so, by what methods?
5. What are the challenges and opportunities with adopting DT-enabling tools for HaH care?

Methods

Review Principles and Protocol

This scoping review followed the principles in the Joanna Briggs Institute (JBI) methodology for scoping reviews [] and is reported in line with the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) [] () and PRISMA-S checklist (). This review followed a published protocol [] and the 5 key methodological stages of scoping reviews []: (1) identifying the research question; (2) identifying relevant studies; (3) selection of relevant studies; (4) charting the data; and (5) collating, summarizing, and reporting the results.

A scoping review was identified as the most appropriate systematic, rigorous approach to knowledge synthesis to capture the required information, as no previous systematic reviews nor evidence exists to answer the research question []. Additionally, many primary studies and evidence in practice are heterogenous in nature, making a scoping review a useful approach to capture the breadth of information and map key concepts required for this work.

Screening and Eligibility

Identifying Relevant Studies

Screening of eligible studies was conducted in line with a predefined protocol [], and the search strategy was supported by a medical research librarian. We searched 6 electronic databases (Embase, MEDLINE, Cochrane CENTRAL, CINAHL, Web of Science, and Scopus; ), and all identified studies were uploaded to a Rayyan database for screening and deduplication []. Gray literature and local evaluation reports relevant to HaH in the United Kingdom were retrieved from National Health Service England, Department of Health and Social Care, and HaH Society websites; the FutureNHS Platform; and related links. Experts in the field and authors were contacted to identify any additional sources. Forward citation searching from the included papers was also conducted.

Primary studies published in the English language were included. To obtain the most up-to-date and relevant information, only studies published from 2019 were included. Initial searches were run until September 11, 2024, then re-run and updated up to September 16, 2025 (). We also recognized that the COVID-19 pandemic may have vastly impacted patient care models and digital technology use; therefore, we wished to capture the most advanced information. Included studies had to report on the monitoring or management of patients with frailty within their own home environment and had to include the reporting of outcomes related to effectiveness, usability, acceptability, and safety. Review articles, protocols, and conference abstracts were excluded as they did not include the primary data required to meet the review objectives.

Selection of Sources of Evidence

In line with JBI guidelines [], a pilot stage was conducted in which 2 authors reviewed a sample of 25 title and abstracts independently and any conflicts were resolved through discussion, allowing screening to continue. The primary researcher (FY) was responsible for full-text screening, with support from a second independent reviewer (MC, HN) to validate the appropriateness of inclusion and exclusion. Discrepancies were resolved through discussion among all 3 reviewers. During the screening phase, reviewers agreed that articles were excluded if the population did not meet the inclusion criteria, did not explicitly mention frailty or meet the definition of frailty as per the British Geriatric Society definition stated in the protocol [], included older adults only or prefrailty only, or set out to assess frailty as an objective or outcome measure. Studies were also excluded if the setting was not a patient’s usual place of residence (ie, a nursing home).

Data Charting

A data extraction form was developed in a format that answered the objectives of the research question covering evidence for each of the 5 architectural layers, as well as country, population, concept, context, applications of the tool, evidence of effectiveness reported, and barriers or facilitators. This was independently piloted with different types of evidence sources (eg, from databases or gray literature) by 3 reviewers (FY, HN, and MC) then collaboratively discussed to highlight and clarify any discrepancies []. It was highlighted that data extraction should focus on the tools used rather than the study or model of care itself. It was also apparent that information obtained from the evaluation reports could often be less structured and more ambiguous, making data extraction more challenging. Data extraction and charting from the included sources of evidence were done initially by the primary researcher (FY) with independent confirmation from the other researchers (MC, WS, MK, HN) to validate the findings. Any uncertainties were clarified via discussion after reviewing the original evidence source. If the required information regarding the tool was not available in the included source, the cited protocol or paper was retrieved for further detail to answer the research objectives.

Critical Appraisal

Critical appraisal was not required in line with JBI guidelines for scoping reviews.

Ethical Considerations

Ethical approval was not required for a scoping literature review.

Collating, Summarizing, and Reporting the Results

Data were collated then summarized to identify themes and key concepts within each category in the data collection form. This was mainly (1) to map the extent and nature of the included studies and their characteristics and (2) to answer the research objectives (ie, the sensing technologies; the communication technologies; information storage, analytics, and visualization methods; ). Finally, the data collection sought to extract any evidence of effectiveness reported in the studies as well as any reported challenges and opportunities of the tools used to support our analysis and interpretation.

Results

Architectural Layers

The results of this review found no existing DT in place for the management of patients with frailty at home nor HaH models. Therefore, in line with the objectives of this review, evidence on DT-enabling tools that could inform any of the 5 architectural layers (ie, sensing, communication, storage, analytics, and visualization) of an HaH DT was sought. These are visualized in the proposed conceptual model in and guided the categorization of the DT-enabling tools in this review based on their functionalities.

‎

Study Characteristics

We included 62 reports from electronic databases and citation searches and 7 gray literature documents that focused on HaH care in the United Kingdom. As displayed in , this resulted in a total of 69 reports (65 studies). Included studies spanned 19 countries across all continents: Europe (n=41), North America (n=17), Asia (n=9), Australia (n=1), and South America (n=1). Over one-half (37/69, 54%) of all included reports used quantitative approaches, followed by 27% (19/69) using mixed methods and 19% (13/69) using qualitative approaches. A large proportion (25/69, 36%) were pilot or feasibility studies testing the tools or intervention. Study designs were described as randomized controlled trials (n=16), cohort studies (n=5), longitudinal studies (n=5), observational studies (n=6), case studies (n=6), evaluations (n=7), feasibility studies (n=10), experimental studies (n=5), quasiexperimental studies (n=1), cross-sectional studies (n=3), or exploratory studies (n=5). Individual study characteristics can be viewed in .

‎

Data Types and Applications of Existing Tools

The types of data captured by the tools () enable an understanding of health care management of patients at home, demonstrating that not only patient data but also environmental-related data and equipment use–related data can be collected. In addition to clinical monitoring, this can provide alerts about early changes in the patients’ usual patterns or behaviors such as the use of appliances in the home (ie, kettles), electricity usage, or use of medication (ie, in digital pill boxes). Many reports presented different tools with different applications and often a combination of functions. As displayed in , a large proportion (36/69, 52%) of reports was focused on measuring frailty markers and the physical function of the patient. Similarly, tools were aimed at improving patient outcomes (n=27) or used for clinical monitoring and review (n=21). The alerting of early deterioration was also a function described in 14 reports; care communication and coordination (n=11) and monitoring of the patient environment (n=10) were also described. Only 6 reports described the use of tools for the education and training of patients (for example, exercise videos, self-care, or nutrition advice).

‎

Sensing Layer

The sensing layer is the fundamental layer within the DT architecture. It is crucial to understand how data are collected for the purpose of informing a DT. Data can be dynamic (changing over time) or static and collected using one or more data-collecting devices [,].

This scoping review included not only technological sensing devices but also any methods that were used to capture data that are used for patient care. Most of the studies relied on manual (human-assisted) methods, wearable sensors, or a combination of both to collect the required data. Manual data collection with equipment, via practitioner observations, or by patient self-reporting (ie, with a questionnaire or diary) was the most prevalent way of capturing data [-]. An array of wearable sensors existed to support with real-time data collection [,,,-], vital sign monitoring [,,,-,-], and assessing functional status [,,,,,-,,,-,,,-] to assist with improving health outcomes [,,-] (see and ).

displays the applications of the tools in relation to the included reports; however, provides a detailed mapping exercise of the applications used to the types of data needed to be collected and the technologies that could be considered within individual architectural layers.

Other types of sensors (listed in ), categorized as physiological measurement sensors (), are nonwearables or nonobtrusive and capture data by activation. Examples include smart weight scales [,,,,,,], “grip balls” to measure grip strength [], or devices that are used to measure gait speed [,,,]. Other nonwearables included ambient sensors that measured motion and activity. Examples included visual (ie, cameras, webcams) [,,] or motion-sensing (ie, motion sensors, mat sensors for sedentary behavior) [,,,,] devices. Some devices had inbuilt hardware that processed the raw data from accelerometers, such as Arduino Nano boards [] used for local data processing, eliminating the need to transmit unprocessed data externally. Similarly, a custom smart speaker built on a Raspberry Pi platform included a 6-microphone audio board, allowing it to capture and process audio data locally [].

Studies also reported on ambient sensors that monitored the environmental surroundings (eg, air quality, water flow, infrared, sound sensors, or GPS [,,,,,]). These would enable the monitoring of any change to usual patterns of behavior in the home. An additional category of sensing included assistive or safety technologies that would be related to patient welfare. This may include detecting any unusual entry or exit to the home by window or door sensors and detecting any hazards in the kitchen with stove guards or gas circuit breakers [,,,-]. Detecting the use of electrical appliances in the home may involve sensors on kitchen appliances (ie, 3Rings smart plug) [] to detect any unusual patterns alerting to deteriorating condition of the patient [,]. Digital calendars and digital medicine dispensers can provide reminders and detect medication administration []. Most studies used a combination of sensors to build a picture of the environment and the patient as part of their intervention.

‎

Communication Layer

The communication layer, sometimes referred to in the literature as the transmission layer or network layer, is responsible for receiving the raw data from the sensing layer and transferring it to the storage layer to be processed and visualized [,]. This layer acts as the intermediary connection or “the bridge” sharing information between the physical layer and the other components in the virtual layer [,,]. In this review, communication methods are any methods used to communicate the information or transmit data, whether this is technology or nontechnology-based. This also included verbal, written, and audiovisual or multimedia as categories of data transmission.

However, digital tools have been shown to transfer data via 3 main categories: (1) mobile or digital messaging, (2) Health Information Exchange or cloud-based communication, or (3) wireless and network-based communication (see , ).

Bluetooth technology was used for the communication layer in 12 reports [,,,,,,,,,,,]. Bluetooth Low Energy (BLE) protocols were also used and are known to be more energy efficient than traditional Bluetooth []. Wireless networks such as WiFi were popular networks of communication in many cases, with some reports emphasizing that a local internet connection was not always required [,]. Nonetheless, studies also reported a privacy-compliant mobile network was needed [,]. Integrating a communication layer into the software or providing 2-way messaging channels were seen as useful for connecting clinicians and patients or caregivers [-,,]. A communication protocol is a key component of the communication layer that governs how data are transmitted between the system components, ensuring efficient and secure transfer across the communication network [,,]. Different protocols were reported in the reviewed literature, including GATT (Generic Attribute Profile) protocols [], RESTful protocols [], or use of an application programming interface gateway []. Some sophisticated technologies used a cloud-based Amazon Lex Chatbot in smart speakers to manage conversations with users using automatic speech recognition in natural language [].

Storage Layer

The storage layer is responsible for hosting the sensed raw data from different sources as well as other integrated data such as historical data that can be used for forecasting future analysis []. Other studies included this as part of the network layer [] or encapsulated it with the communication or analytics layer. We have presented this as its own layer for a more granular examination, to identify how data are stored, and to clarify what potentially needs to be considered to develop an HaH DT prototype.

As represented in , the storage layer was the least described in the included reports (n=18). However, we categorized these as cloud-based storage solutions, server-based storage solutions, databases, or external storage solutions. The most used storage options described were cloud-based platforms [,,,,,,,,,], mobile storage (such as apps) [,,,,,], or remote servers []. Secure servers were described on either desktops or mobile devices []. Few studies described using secure Amazon Web Services as a storage method [,]. NoSQL databases [] and MySQL databases [,] were also used, representing the complexity of the types of data in patient care at home.

Analytics Layer

This layer is responsible for data preparation, processing, and translation to produce meaningful insights and can sometimes be referred to as the computing layer [,]. In the majority of the literature, this comprised all the data-driven models []. In the analytics layer, data may go through data modeling, data mining, or data fusion to consider the current physical state and manage big data to enable and represent future predictions []. Prior to analysis, the data may go through a stage of data aggregation. Data aggregation was mentioned in 7 reports [,,,,,,], including measuring changes in clinical scales or multiparametric data analysis [] to understand and collate the data retrieved from the sensors, although this would not constitute technical analysis itself.

In the analytics layer, methods could fall under any of 4 types: descriptive (What has happened?), diagnostic (Why have we seen this result?), predictive (What might happen?), or prescriptive (What should we do?). However, the included reports described methods corresponding to only 3 of the 4 analytics descriptions: descriptive, predictive, and less so prescriptive methods.

Descriptive analytics could encompass pattern analysis or a variety of statistical analyses as represented in . For example, tests like Cohen kappa were used for categorical data from motion sensors, Bland Altman plots were used for continuous data (ie, sedentary time and stair climbing time), and bivariate correlation analyses were used for weight data []. In addition, principal component analysis has been used for dimensionality reduction with large datasets [,].

Predictive analysis allows forecasting of future possibilities and was described in 8 reports [,,,,,,,], primarily using ML algorithms. This could either be supervised ML (which uses labeled data to train algorithms) or unsupervised ML (which uses clustering on unlabeled data) []. Examples of supervised ML included methods of regression (ie, using logistic regression analysis) [,] or classification (ie, using tree-based classifiers [,,] or support vector machines [,]). Reports also described the use of artificial neural networks, deep learning (multilayer perceptron neural network or with an artificial neural network architecture) [], and neuro-fuzzy systems or adaptive neuro-fuzzy inference systems [].

On the other hand, unsupervised ML would, for example, encompass neural networks or hierarchical cluster analysis like dynamic time warping distance matrix []. This can be a method of time-series analysis, which has been demonstrated to distinguish between ascension and descension on a stairway by measuring changes in speed and frequency and force on a handrail biaxial sensor [].

One report [] used universal sequence mapping as a method to model human frailty through smart home sensor readings. Alternative methods, namely approximate entropy and sample entropy, were compared for sensitivity using Monte Carlo simulation. Markov-Chain analysis was then used to understand which method had higher precision to understand behavioral complexity as a potential biomarker for frailty [].

Prescriptive analysis evidence demonstrated this can support decision-making using methods such as modeling (ie, 3D digital simulation or virtual patient modeling []). One study also used social media analysis in their platforms to assess mental frailty or personality trait shifts (ie, with language analysis) to process the users’ typed text, social interactions, or questionnaires [].

Visualization Layer

This layer is a way of presenting the analyzed data and generating insights to enable informed decision-making by clinicians, patients, or caregivers. Some studies combined this with analytics as a “data analytics and visualization layer“ []; however, for the purposes of this study, we realized that these layers are primarily distinct. In this review, we also separated the visualization layer from the feedback mechanisms in a DT.

This layer was categorized in 3 ways: (1) graphical and dashboard visualizations, (2) 3D visualization, and (3) software or hardware.

The graphical and dashboard visualizations are represented in 2D form. Common methods involved digital dashboards either on a computer or mobile device [,] or remote telemedicine center []. One study also described the use of universal sequence mapping both in analytics and as a way of visualizing patterns similar to chaos game representations [].

A 3D visualization, such as with point clouds, was used to represent 3D skeletal reconstruction by combining IMU data, RGB images, and depth measurements processed by neural networks to understand functional activity []. Similarly, visualization of joint coordinates using visualization tools such as Master Active Gestures ID can help assess sitting or standing behavior []. Alternatively, visualization of a virtual living room through an interface was possible [].

Software or hardware, such as gaming systems, was used to visualize progress or weekly changes [], for example with exercise or walking speed, and can incentivize physical activity with digital rewards or ranking points. Such systems may include augmented reality glasses [] or interactive platforms. Interfaces for this software can be accessed through the web or mobile apps. Some integrated platforms such as in-built interfaces on a wall or television in the patient’s home can also include a virtual embodied agent (Robin the Robot) to support and tailor advice to users [].

Feedback Mechanisms

In addition to the visualizations described in the previous section, methods for feedback to the users (clinicians, patients, caregivers) were used and categorized into 3 groups: (1) health alerts and notifications, (2) health feedback and reports, and (3) mobile or digital platforms.

Health alerts and notifications include automatic alert triggers when a risk is identified. One example is alert-triggered health interventions, which raise an automatic call to the clinician’s hub if a high risk is detected according to its risk categorization []. Calls may also be actioned directly to the caregiver [,]. Alternative forms are notifications via email or text message or to the emergency services [].

Health feedback and reports involve email reports or letters with health information or location [,,,]. Visual reports with videos or photos are also common [,,]. Some reports have also shown voice or audio feedback [] or used specific devices like mobility feedback devices for tailored information [].

Mobile or digital platforms are also commonly used for feedback. Some are integrated with other platforms such as electronic health systems and some are via web interfaces or applications [,] (ie, via a smartwatch []).

As described in , 26 of 69 reports explored the user experience including acceptability and usability, especially as these tools were in infancy of development and implementation. However, only 4 reports explored the impact on care delivery, the system, or clinical outcomes. Where reports demonstrated positive findings, there was a predominant use of manual sensing measures and using mobile apps and self-reporting (). Nonetheless, there is an emergence of wearable technologies, including wearable accelerometers that can be wrist-worn, lumbar-worn, thigh-worn, worn in a smartvest, or worn as a pendant sensor. Devices for smart weight and blood pressure monitoring as well as devices that measure gait speed, sit-to-stand transitions, and movement in the environment were also prominent.

Challenges and Opportunities

Studies reported many challenges with the use of the tools that would need to be considered in future work, but they also described many opportunities. Challenges in these studies were categorized into 4 themes: (1) patient or carer factors, (2) device factors, (3) external factors, and (4) organizational or administrative factors.

Patient or Carer Factors

Most studies identified various patient-related factors impacting successful adoption of digital tools. These included varying levels of digital literacy [,,,,], previous experience with technology [], technophobia [], and a general preference for face-to-face interactions [], all affecting acceptability. Perceived benefit [,], and willingness [,,,,,] to engage are critical yet were often influenced by poor understanding of the technology’s role, unclear instructions, or complex processes. Where self-reporting was needed, it was recognized that this can lead to underestimating or overestimating measures [,]. Physical or visual impairments can affect usability, including device readability or difficulties with touchscreens, multiple-tapping, and managing pop-up notifications [,,,]. Other medical conditions (eg, psychiatric or cognitive disorders, dementia) may affect memory or concentration, hindering device use [,,]. Furthermore, articulation issues were found to hinder voice recognition by assistive robots and led to inadequate conversation [].

Some patients found wearables uncomfortable and inconvenient [,,], disrupting daily activities (eg, washing), or experienced disturbances from LED lights or main leads [], potentially attenuating psychological and physical burden (ie, stress, sleep disturbance, anxiety, depression) [,]. Variabilities in-home routines can also affect the ability to individualize care []. Carers reported burden where patients required support and had difficulties navigating technology independently. They sometimes felt they had to be “on-call,” leading to increased expectations on their care, which reduced their autonomy []. Furthermore, notifications to caregivers can also cause frustration, affecting well-being [,].

Device Factors

Beyond device complexity for certain patient groups (eg, frail older adults), this evidence highlighted uncertainties with device accuracy [,] and potential for false readings [,,]. Some studies reported difficulties with devices distinguishing between subtasks or detecting visitors, leading to noisy or biased spatial measurements []. There were also concerns that the accuracy may not have matched hospital devices (eg, ECGs) [] or varied between standardized clinic or home settings (eg, the 6-minute walk test) []. Current devices also lacked validation for specific populations (eg, those with frailty), leading to potential inaccuracies in algorithms like step counts []. Short or inconsistent data sequences, storage limitations [], and missing values [] further compromised the quality of results. Concerns also included corrupt data, device failure, and malfunctions [,]. Frequent recharging was also reported as burdensome [,], and incompatibility of devices to synchronize with platforms used by health care professionals can limit practical use [,].

External Factors

External factors outside of the home, such as internet signal or power outages, can also affect notifications and data quality [,,]. Factors in the surroundings such as the size, shape, and geometry of a patient’s home environment or furniture can affect the practical application of sensors or standard clinical tests such as walking speed between two points [,]. This can result in artifacts in the data, adding a layer of complexity, especially if visitors are present, making data evaluation difficult. The environment cannot always be anticipated (eg, availability of sockets or flat surfaces), making locations for the devices challenging []. There is also a higher degree of variability in the home, dependent on the patients’ motivation or daily occupational demands, which cannot be predicted. Some patients may also find sensors on their furniture visually unpleasant, such as iAQ sensors on the dining table [].

Organizational Factors

The use of devices often requires efficient and secure communication and coordination between services. Challenges were observed with variable adoption and understanding when remote monitoring was suitable []. A degree of model reorganization was needed to ensure prompt responses as well as access to clinicians out of hours [,]. Factors such as staff capacity, planning, and managing administration (if paper was used) were some of the challenges encountered []. Interoperability with clinical systems, data quality, and coding were also problematic [,,].

Opportunities

Studies reported that the tools offered positive motivation for users [,,], improving physical activity [,,,,] and self-management [,,,,]. Furthermore, they provided a sense of reassurance and safety for patients and carers [,,,]. Opportunities for autonomous and continuous monitoring [,,] as well as integrating data from multiple sensors can increase the accuracy of information [,] and personalization [,,,,,,] and provide the potential to evaluate trends to enhance decision-support systems []. At a service level, these can support early identification and referral [,], support cost-effectiveness of services by reducing the number of clinical visits [,], decrease waiting times [], and support scalability of services []. Furthermore, information sharing between services, clinicians, and for research [] means that data can be used as a proxy for frailty markers [,], to create frailty assessment tools (ie, web applications) [], and to support integrated and collaborative care (ie, supporting staff handovers) [,,,,]. Ways to overcome practical challenges with devices were considered in some reports; these included avoiding recharging by using induction charging [,] or hiding devices in socially acceptable objects [].

Discussion

Principal Findings

This review aimed to explore the existing evidence for the potential DT architectural components that are tools or functionalities currently used in the management of patients at home with frailty and presents a novel conceptual model of an HaH DT ().

The model is supported by previous definitions of DTs expressing that data acquisition and feedback should be dynamic, be timely [], and have bidirectional communication [,]. Prior studies describing DTs have typically focused on specific aspects such as body organs, drug manufacturing, or device and facility management rather than holistic management []. Emerging evidence shows great promise of DTs in home care; however, a lack of in-depth studies exist, making implementation difficult [].

The developed blueprint (conceptual model) presented in this review provides detailed information about the tools that can be used in an HaH DT and can be used to inform the development of a prototype for user testing. An example of a use application such as the monitoring of functional activity as a marker of frailty derived from the blueprint of an HaH DT detailed in is shown in .

‎

The results improve understanding so researchers, practitioners, and solution providers can better navigate the complexity of an HaH DT. This will help identify which data needs to be collected and how the data are managed in each layer, in relation to the specific applications.

This review recognizes that management as part of an HaH DT can support either at the service level (to support workflow management) or the patient level (ie, remote monitoring). Additionally, development of a DT in this context can be understood as a system of systems (ie, comprised of a DT of the home environment and a DT of the patient).

A taxonomy of existing sensing technologies has been identified that can be used both to monitor the patient and the environment, building a comprehensive picture of patient status and support decision-making. These offer the opportunity for collecting active and passive sensor data [] (including the use of unobtrusive sensing technologies [,]), which can benefit the implementation of DTs for patients with frailty. This builds on current evidence around remote monitoring in HaH that aims for early prediction of patient outcomes [,]. In this review, communication technologies currently focus on Bluetooth and network-based wireless methods; however, the emerging use of advanced IoT technologies using 5G and AI may warrant further exploration.

Data Governance, Security, and Ethical Considerations

Knowledge on efficient and secure data management (storage, integration, interoperability) with current health care systems remains crucial. Previous work has identified the need for data repositories such as ”data lakes” or data warehouses to enable data aggregation from multiple technologies and allow for data to be structured and analyzed in DTs []. Although the included studies demonstrated examples of either edge computing or cloud computing, health care systems are increasingly encouraging a cloud-first approach to improve efficiency and organizational agility and to enable scalability []. These may include public cloud services such as Google Cloud, Amazon Web Services, or Microsoft Azure []. Understanding the different data types from this scoping review and recognizing that data can fall into one of 3 types (structured, semistructured, and unstructured []) demonstrates the complexity of health care at home and the need for advancing knowledge around enhanced data management structures. Proposed DT frameworks suggesting data-centric approaches recognize that multimodal data integrating information from various health records are likely and potential solutions to aid implementation may involve in-silico studies using synthetic data []. Furthermore, the challenges with data acquisition, accuracy, and quality have similarly been highlighted previously [,,,]. In-depth information on data security was lacking in the included reports; however, some of the literature discussed potential solutions such as blockchain technology []. Data security measures need to be considered from development and inception, abide by security protocols and regulations, and consider aspects like robust encryption, authorization, and multifactor authentication to mitigate any risks of data leakage [].

Other considerations such as fairness, accountability, transparency, and explainability when designing and implementing data-driven solutions and AI algorithms in a DT system should be integrated [] . Cybersecurity when using IoT devices in health care remains a concern that can have serious consequences for the patient and the health care organization []. However, the integration of security into digital health is increasingly emphasized as we use more digital technology solutions. Carboni et al [] discussed the balance needed between security and care practices, highlighting the perspective that health care systems in reality can be complex environments and solutions must involve end users rather than only the technology itself. Open conversations with users (both staff and patients) and participatory design approaches are methods to improve the adaptability and adoptability of advanced digital technology moving forward. Despite the potential of passive remote monitoring and DTs, previous work has likened remote monitoring to having “nanny cams” [], highlighting that evidence and data are still required to promote their ethical use [,,,].

Potential for Advanced Data Analytics

Most studies in this review described tools that used descriptive and predictive analytics, and some used prescriptive (clinical decision support). However, there is a need to explore the use of diagnostic analytics (ie, why is something happening?) by identifying anomalies in trends or performing root-cause analysis. In HaH, previous studies attempted to explore tools for risk prediction using predictive modeling, but these appear to primarily be case management tools and not necessarily dynamic nor real-time [,]. Emerging studies in health care have developed advanced risk prediction models to support decision-making in high-pressure, time-critical health care settings such as ambulance clinical transport decisions [] . Understanding such novel approaches and how they integrate with electronic patient records is highly valuable []. Other examples [,] that also use ML algorithms in health care are emerging to alert to a patient’s deterioration early; however, these are hospital-based and may not reflect nonhospital settings. Health care is evolving, with increasing use of “command centers” to support patient flow and decision-making [,]. Although these update a dashboard in real time, they are often centralized in hospitals and still require manual input of information by staff. They can support workflow management and efficiency, aiming to enhance safety []; however, they may not have simulation or prediction capabilities like DTs. Moreover, their ability to adapt to complex home environments remains underexplored.

This review advances findings from other literature recognizing the potential of DTs in the management of hospital processes [,] to enhance efficiency or optimize environments []. For patient management, previous studies [] have explored the potential of wearables as trigger warning alerts [,] that can be used in DT technology. In current practice in HaH, evidence for continuous vital sign monitoring using wearables shows benefit, and use is increasing in clinical practice; however, robust evidence is limited [,]. Adding to emerging evidence on DTs that are in early stages of development [], this review demonstrates how existing technologies can be utilized in DTs specifically for HaH, as well as identifying key architecture that warrants further understanding, such as information storage, analytics, and visualization.

Barriers to Adoption and Strategies for Integration

This review has provided some valuable learning regarding the barriers to adoption of digital technologies in the home for patients with frailty. These predominantly include digital literacy and understanding, both for patients and the workforce, followed by usability of the technology. Concerns around device accuracy, longevity, and interoperability and integration with current health care systems were also major challenges, which is recognized in some emerging studies related to remote monitoring [,]. Some potential strategies to overcome these would be to explore organizational readiness and ensure any prototype is co-designed with potential stakeholders (patients, carers, and health care organizations). Furthermore, improving awareness and understanding of the DT system to be deployed would be needed by factoring in training [], funding, and workforce capacity.

Strengths and Limitations

This review provides a systematic approach to reviewing current evidence on the tools used for the management of patients at home with frailty. As limited literature on HaH exists, this review was comprehensive enough to gather learning from the general management of patients at home. However, as the population in question was those with frailty, we may have excluded some studies that involved interventions that would have been useful to explore for nonfrail patients or those only at risk. During the search, many studies were correlation studies looking at the association of a parameter with frailty, and these were excluded as they did not meet the inclusion criteria. The search was comprehensive at trying to include all relevant search terms; however, we recognize that other search terms not included may have been helpful (ie, “Healthcare 4.0” or “5G”). Furthermore, the restricted inclusion of only those documents published in the past 5 years could have meant that helpful studies to answer our question may have been excluded.

Implications for Future Work

This review has highlighted many of the technological capabilities for DTs in HaH as a first step to understanding the potential of current technologies in use for managing patients at home with frailty. This review provides the foundations to enable stakeholders to advance research and development in areas where there are knowledge gaps and consider how an HaH DT can effectively operate within current health care systems to enable safer, personalized, and timely care. However, to advance this concept further, we need to understand its potential application in current practice and its acceptability before it is developed and piloted. Using frameworks such as the Non-adoption, Abandonment, Scale-up, Spread, Sustainability (NASSS) framework [] or the 6 categories in the DT consortium capabilities periodic table [] would be helpful as a basis for understanding how the generated conceptual model may be implemented in practice. Furthermore, design of a potential HaH DT prototype and demonstration as a “show home” would benefit from stakeholder involvement and co-design to ensure that any advancing technologies are user-friendly, have supportive infrastructures, and have the appropriate educational support in place []. For organizations that wish to take learning from this review forward, understanding these 5 core architectural layers provides the fundamental knowledge to build on this foundation. Knowledge about how these interconnect within the current health care systems needs to be understood, especially with regards to data management and transfer of data between the 5 layers. Before this can be deployed in real health care settings, further research or small-scale prototype testing will be required, with a focus on a specific clinical cohort of patients and to determine which data types are appropriate for collection that would usefully alert to early deterioration and methods for coordinating these alerting systems or feedback. Evidence shows that a wealth of sensing technologies already exist, but understanding how these can be adapted to fit in with current systems is necessary. Inclusive methods for communication that do not rely on a patient to have connectivity are important to avoid digital exclusion. It would be useful to further understand secure data storage in health care or linking in with secure data environments before prototype development and the accuracy of potential predictive analytics.

Conclusion

DTs in HaH offer a novel solution to prediction and prevention, reducing the burden on patients and health care systems and potentially improving clinical outcomes. Leveraging the use of technology-enabled care can enhance remote monitoring in real time to support clinicians with delivering care efficiently and safely. This review enabled us to understand the 5 architectural layers that can support stakeholders in advancing research and development of forward-thinking systems such as DTs, particularly within complex settings like HaH for patients with frailty. It also identified knowledge gaps in the existing evidence and allowed us to consider where health care systems should explore improvements to current structures to achieve successful adoption in a rapidly evolving landscape of digital solutions.