Category: 3. Business

  • Trevi Therapeutics Reports Third Quarter 2025 Financial Results and Provides Business Updates

    Trevi Therapeutics Reports Third Quarter 2025 Financial Results and Provides Business Updates

    Company preparing to initiate comprehensive Phase 3 program for chronic cough in patients with idiopathic pulmonary fibrosis in first half of 2026

    Company ended the third quarter of 2025 with $194.9 million in cash, cash equivalents and marketable securities with expected cash runway into 2028

    Management to host a conference call and webcast today at 4:30 p.m. EST

    NEW HAVEN, Conn., Nov. 13, 2025 /PRNewswire/ — Trevi Therapeutics, Inc. (Nasdaq: TRVI), a clinical-stage biopharmaceutical company developing the investigational therapy Haduvio™ (oral nalbuphine ER) for the treatment of chronic cough in patients with idiopathic pulmonary fibrosis (IPF), non-IPF interstitial lung disease (non-IPF ILD), and refractory chronic cough (RCC), today announced financial results for the quarter ended September 30, 2025, and provided business updates.

    “Following positive clinical data for both IPF chronic cough and RCC earlier this year, our strong progress continues. We have been executing on the studies necessary to advance our IPF chronic cough program and are on track to submit our End-of-Phase 2 meeting request to the FDA in the fourth quarter,” said Jennifer Good, President and CEO of Trevi Therapeutics. “We look forward to discussing our development program with the FDA and are building a robust and comprehensive package for those discussions. Our overall corporate strategy is built on a clear path for growth, focused on specialty indications in chronic cough that currently have no approved therapies in the U.S. and have significant negative impacts on the quality of life of the patients with these conditions.”

    Third Quarter 2025 Financial Results and Recent Business Highlights 

    Chronic Cough in IPF

    • The Company is preparing to request an End-of-Phase 2 meeting in the fourth quarter of 2025 and to initiate its Phase 3 program in the first half of 2026.
    • The safety review committee for the Phase 1 respiratory function and safety study in patients with IPF, which is referred to as TIDAL, met to review data for the sentinel cohort of patients and concluded there were no safety signals and gave approval to complete enrollment. The study is expected to be completed in the fourth quarter of 2025 and available data will be included in the End-of-Phase 2 meeting package.
    • The Company successfully completed a Phase 1 drug-drug interaction study in healthy adult participants to evaluate the co-administration of nalbuphine ER with standard of care antifibrotic therapies, pirfenidone or nintedanib. The results of the study showed no clinically meaningful pharmacokinetic findings for nalbuphine ER or either of the antifibrotics when given in combination.
    • Topline results from the Phase 2b CORAL trial were presented at the CHEST 2025 Annual Meeting.

    Refractory Chronic Cough

    • Following the positive Phase 2a RIVER trial results earlier this year, the Company is planning to initiate a Phase 2b RCC study in the first half of 2026.
    • Results from the RIVER trial were presented at both the CHEST 2025 Annual Meeting as well as at the ERS Congress 2025.

    Corporate

    • The Company ended the third quarter of 2025 with $194.9 million in cash, cash equivalents and marketable securities, with expected cash runway into 2028.

    Third Quarter 2025 Financial Highlights  
    Research and development (R&D) expenses: R&D expenses for the third quarter of 2025 decreased to $10.1 million from $11.2 million in the same period in 2024, primarily due to decreased clinical development expenses for the Company’s Phase 2a RIVER trial, Human Abuse Potential study, and Phase 2b CORAL trial, all of which were actively enrolling patients in the prior year period. These decreases were partially offset by increased costs for the Company’s recently completed Phase 1 drug-drug interaction study and personnel-related expenses.

    General and administrative (G&A) expenses: G&A expenses for the third quarter of 2025 increased to $3.8 million from $2.9 million in the same period in 2024, primarily due to an increase in professional fees and personnel-related expenses.

    Other Income, net: Other Income, net for the third quarter of 2025 increased to $2.1 million from $0.8 million in the same period in 2024, primarily due to an increase in interest income from higher invested cash equivalent and marketable securities balances.

    Net loss: For the third quarter of 2025, the Company reported a net loss of $11.8 million compared to the net loss of $13.2 million in the same period in 2024.

    Conference Call and Webcast 
    To participate in the live conference call by phone, please dial (877) 870 4263 (domestic) or (412) 317 0790 (international) and ask to join the Trevi Therapeutics call. No code is necessary for access. A live audio webcast will be accessible from the ‘Investors & News’ section on the Company’s website at www.TreviTherapeutics.com. An archived replay of the webcast will also be available for 30 days on the Company’s website following the event. 

    About Trevi Therapeutics, Inc.   
    Trevi Therapeutics, Inc. is a clinical-stage biopharmaceutical company developing the investigational therapy Haduvio™ (oral nalbuphine extended-release) for the treatment of chronic cough in patients with idiopathic pulmonary fibrosis (IPF), non-IPF interstitial lung disease (non-IPF ILD), and refractory chronic cough (RCC). Haduvio is the first and only investigational therapy to show a statistically-significant reduction in cough frequency in clinical trials across both patients with IPF chronic cough and in patients with RCC. Haduvio acts on the cough reflex arc both centrally and peripherally as a kappa agonist and a mu antagonist (KAMA), targeting opioid receptors that play a key role in controlling chronic cough. Nalbuphine is not currently scheduled by the U.S. Drug Enforcement Agency.

    Chronic cough in patients with IPF and non-IPF ILD is a condition with high unmet need and no FDA-approved therapies. There are ~150,000 U.S. patients with IPF, and two-thirds of these patients are faced with uncontrolled chronic cough. Additionally, there are ~228,000 U.S. patients with non-IPF ILD, with 50-60% having uncontrolled chronic cough. The impact of chronic cough is significant, with patients coughing up to 1,500 times per day. This consistent cough, and any associated damage, may lead to a higher risk of morbidity and mortality, including worsening disease, a higher risk of progression, increased respiratory hospitalizations, and a decline in patients’ quality of life.   

    RCC is a condition with high unmet need and no FDA-approved therapies. RCC is defined as a persistent cough lasting >8 weeks despite treatment for an underlying condition (i.e., asthma, gastroesophageal reflux disease, non-asthmatic eosinophilic bronchitis, upper airway cough syndrome, or post-nasal drip) and includes unexplained chronic cough. There are ~2-3 million U.S. patients with RCC, and it is believed to be associated with cough reflex hypersensitivity involving both the central and peripheral nervous systems. RCC is highly debilitating and may impact patients physically, psychologically, and socially.  

    Trevi intends to propose Haduvio as the trade name for oral nalbuphine ER. Its safety and efficacy have not been evaluated by any regulatory authority. 

    For more information, visit www.TreviTherapeutics.com and follow Trevi on X (formerly Twitter) and LinkedIn.

    Forward-Looking Statements  
    Statements contained in this press release regarding matters that are not historical facts are “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. Such statements are subject to risks and uncertainties and actual results may differ materially from those expressed or implied by such forward-looking statements. Such statements include, but are not limited to, statements regarding Trevi’s business plans and objectives, including future plans or expectations for Haduvio and plans and timing with respect to clinical trials and clinical data, as well as regulatory submissions, expectations regarding Trevi’s uses and sufficiency of capital, and other statements containing the words “believes,” “anticipates,” “plans,” “expects,” and similar expressions. Risks that contribute to the uncertain nature of the forward-looking statements include: uncertainties regarding the success, cost and timing of Trevi’s product candidate development activities and clinical trials; the risk that positive data from a clinical trial may not necessarily be predictive of the results of later clinical trials in the same or a different indication; uncertainties regarding Trevi’s ability to execute on its strategy; uncertainties with respect to regulatory authorities’ views as to the data from Trevi’s clinical trials and next steps in the development path for Haduvio in the United States and foreign countries; uncertainties inherent in estimating Trevi’s cash runway, future expenses and other financial results, including Trevi’s ability to fund future operations, including clinical trials, as well as other risks and uncertainties set forth in the quarterly report on Form 10-Q for the quarter ended June 30, 2025 filed with the Securities and Exchange Commission and in subsequent filings with the Securities and Exchange Commission. All forward-looking statements contained in this press release speak only as of the date on which they were made. Trevi undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made.

    Trevi Therapeutics, Inc.

    Selected Balance Sheet Data

    (unaudited)

    (amounts in thousands)




    September 30,
    2025



    December 31,
    2024

    Cash and cash equivalents


    $

    56,869



    $

    34,097

    Marketable securities



    138,058




    73,525

    Working capital



    189,258




    98,919

    Total assets



    199,356




    110,900

    Stockholders’ equity



    189,788




    99,644

    Trevi Therapeutics, Inc.

    Selected Statement of Operations Data

    (unaudited)

    (amounts in thousands, except per share amounts)




    Three Months Ended
    September 30,



    Nine Months Ended
    September 30,



    2025



    2024



    2025



    2024

    Operating expenses:












    Research and development


    $

    10,085



    $

    11,224



    $

    27,285



    $

    30,049

    General and administrative



    3,831




    2,863




    11,823




    9,232

    Total operating expenses



    13,916




    14,087




    39,108




    39,281

    Loss from operations



    (13,916)




    (14,087)




    (39,108)




    (39,281)

    Other income, net



    2,099




    814




    4,617




    2,739

    Loss before income taxes



    (11,817)




    (13,273)




    (34,491)




    (36,542)

    Income tax benefit



    15




    31




    48




    46

    Net loss


    $

    (11,802)



    $

    (13,242)



    $

    (34,443)



    $

    (36,496)

    Basic and diluted net loss per common share outstanding


    $

    (0.08)



    $

    (0.13)



    $

    (0.26)



    $

    (0.36)

    Weighted average common shares used in net loss per share attributable to common stockholders, basic and diluted



    145,104,986




    101,282,228




    131,122,754




    100,616,111

    Investor Contact 
    Jonathan Carlson 
    Trevi Therapeutics, Inc. 
    (203) 654 3286 
    [email protected] 

    Media Contact 
    Rosalia Scampoli 
    914-815-1465 
    [email protected]

    SOURCE Trevi Therapeutics, Inc.

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  • Bavarian Nordic chair Debruyne steps down after failed takeover – Reuters

    1. Bavarian Nordic chair Debruyne steps down after failed takeover  Reuters
    2. Nordic Capital, Permira takeover offer for Bavarian Nordic falls through  Reuters
    3. Bavarian Nordic Announces Changes to the Board of Directors  The Manila Times
    4. Danish Shareholders Association on Bavarian: Shareholder democracy proved to work  medwatch.com
    5. Consortium consisting of Nordic Capital and Permira announces preliminary result of the takeover offer to shareholders of Bavarian Nordic and that the Offer is withdrawn and will not be completed  Yahoo Finance

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  • Atomic insights could boost chemical manufacturing efficiency

    Atomic insights could boost chemical manufacturing efficiency

    URochester researchers develop algorithms that reveal how propane becomes propylene for everyday products.

    Countless everyday products from plastic squeeze bottles to outdoor furniture are derived by first turning propane into propylene. A 2021 study in Science demonstrated chemists could use tandem nanoscale catalysts to integrate multiple steps of the process into a single reaction—a way for companies to increase yield and save money. But it was unclear what was happening at the atomic level, making it difficult to apply the technique to other key industrial processes.

    Researchers at the University of Rochester developed algorithms that show the key atomic features driving the complex chemistry when the nanoscale catalysts turn propane into propylene. In a study published in the Journal of the American Chemical Society, they discuss these intricate reactions that are complicated by materials in multiple states.

    “There are so many different possibilities of what’s happening at the catalytic active sites, so we need an algorithmic approach to very easily yet logically screen through the large amount of possibilities that exist and focus on the most important ones,” says Siddharth Deshpande, an assistant professor in the Department of Chemical and Sustainability Engineering. “We refined our algorithms and used them to do a very detailed analysis of the metallic phase and oxide phase driving this very complex reaction.”

    Desphande and his chemical engineering PhD student Snehitha Srirangam found several surprises in their analysis. The oxide in the chemical reaction preferred growing around defective metal sites very selectively, which proved critical for the stability of the catalyst. And even though the oxide can exist under different chemical compositions, it never really left its function of being around the defective metal sites.

    According to Deshpande, researchers can leverage this knowledge and the team’s algorithmic approaches to understand the atomic structure of other chemical reactions such as methanol synthesis used for products ranging from paints to fuel cells. Eventually, he believes this could help companies strategically seek more efficient ways to produce propylene and other industrial materials and rely less on the trial-and-error methods they have used for decades.

    “Our approach is very general and can open the doors to understand many of these processes that have remained an enigma for decades,” says Deshpande. “We know these processes work, and we produce tons of these chemicals, but we have much to learn about why exactly they’re working.”

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  • A recent breakout points to a ‘stealth bull market’ in this exchange stock, according to the charts

    A recent breakout points to a ‘stealth bull market’ in this exchange stock, according to the charts

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  • Standard Bank’s CEO on Driving Sustainable Growth and Shared Prosperity

    Standard Bank’s CEO on Driving Sustainable Growth and Shared Prosperity

    ALISON BEARD: I’m Alison Beard and this is the HBR IdeaCast.

    Our goal of this show and Harvard Business Review in general is to bring you all the research, insights and advice you need to become a better leader and push your organization forward. A big part of that is learning from practitioners, the people running some of the world’s most successful businesses, to see what they’re doing and where they think the world is going next. That’s why each year we host HBR’s Future of Business virtual conference, bringing in leading CEOs from various industries to speak about hot topics like artificial intelligence, geopolitical uncertainty and corporate social responsibility.

    On Thursdays for the next month, we’ll be sharing some of those conversations here on IdeaCast, giving you a view into strategy making and innovation at some of the world’s top companies and helping you see how you might apply their thinking to your own.

    First up is Sim Tshabalala, the CEO of Standard Bank, which is Africa’s largest bank and biggest lender by assets. Sim grew up in Soweto Township during South Africa’s apartheid era, so he learned early on how financial access or the lack thereof can improve or damage lives. After working as an attorney, he joined Standard Bank in 2000 and over the next 13 years worked his way up to the CEO role where he’s overseen both geographic expansion and digital transformation. I spoke with him about his journey to the C-suite, how Standard is navigating the new AI era and why businesses need a broader purpose like promoting prosperity among underserved populations. Here’s our conversation.

    So Sim, that rise from Soweto to the helm of Standard Bank is really remarkable. And I’m just interested to hear how that upbringing played into your decision to go into finance and then your leadership of the bank with a modern day purpose that moved beyond its history.

    SIM TSHABALALA: I grew up in a family that had a great admiration for education. My dad, for example, used to love reading Dostoevsky and had The Brothers Karamazov and so on his shelf. And I would read that. And my mom was a nurse. My grandfather was a school teacher and so was my grandmother. And so that family was a family that thought very highly of education and the need for the next generation to do better than the previous one.

    I was sent to a Catholic school in South Africa called Sacred Heart College, matriculated there, went on to study law, majored in philosophy in my undergraduate degree, and then did a law degree thereafter. Practiced a little bit in South Africa for two years, discovered I did not like it, and went to the University of Notre Dame to do a master’s in public international law.

    But I wanted to make a difference. And a friend of mine who was working in a small structured finance house said, “How about coming to join us?” I joined them and I used that desire to make a difference in society, that desire to be at the center of activity, the understanding of law, human rights, using all of that to make a difference to stakeholders, and it was therefore at the center of my personal vision.

    ALISON BEARD: Yes. And the company has a specific mission that is focused on prosperity for all. So why do you think that that’s important beyond prosperity for shareholders or prosperity for clients who generate suitable margin? Why this expansive purpose?

    SIM TSHABALALA: To be frank, we learned very, very quickly, the current management team that we needed to identify and re-articulate why Standard Bank exists. And we went through a long process of self-examination, thinking through where the group comes from. As you would know, it was formed in October 1863. So it’s an old company under the same name, by the way.

    And we thought deeply about why we exist. Our founders were people that were wool traders in Port Elizabeth in South Africa, and they were selling wool to the United Kingdom and they therefore needed intermediation services. And so what is our purpose? Our purpose is to help people to grow, whether it be their own businesses, their families, their communities, and their environments. Hence, the purpose of the organization described as Africa is our home, we drive her growth.

    What do we mean by growth? Simply as a banker, it means on the one hand, GDP growth, and then on the other hand, making sure that people are participating fully in that growth, so including as many members of society in that growth as is practical. That is very important, Alison, because the biggest input in the calculation of our equity, our cost of capital, and indeed our cost of debt is country risk. And if the country that we are operating in is not safe, it just increases the cost of capital.

    And that is why it is so important for us as we think through generating returns that adequately reward our investors for being invested in us to think through all the components that make up that return. So in order for you to generate the revenues, you need to be in the right environment, therefore country risk matters. Therefore, the risk of the communities where you operate matters. Therefore, you need to think about all your stakeholders, your shareholders, your capital providers, your customers, your staff, and indeed the community where you are making your money.

    ALISON BEARD: Do you think that there are unique insights that you have as a bank that’s operating in many African countries about how to navigate very fast changing, sometimes politically uncertain environments that you could share with other businesses now as that geopolitical uncertainty seems to be ratcheting up for everyone?

    SIM TSHABALALA: In the last decade or so, or last couple of decades, the African continent has been a place where we’ve seen incredible innovations. M-Pesa, for example, in East Africa, saw huge developments in payments. We’ve seen great strides in inclusion through the use of telecoms by the cell phone companies, the combination of work done by cell phone companies and fintechs to include more people, huge, huge contributions to innovation. There’s a company that is listed on the Johannesburg Stock Exchange. That company is involved in using the platforms of telcos and uses data that is generated by those telcos in partnership with banks to provide nano loans or small loans to borrowers. That is a huge innovation, and it’s a company we’ve been involved in from day one, and the company is called Optasia.

    It’s a fascinating story of a company that starts in 2012, now a unicorn, but a company that is calculated to provide services to millions of people. They’ve got about 121 million users and what a story of inclusivity, they operate in 38 countries. So here’s an opportunity to innovate on the African continent. As far as geopolitics is concerned, it’s a huge topic. And perhaps let me just mention that as Africans, we try and operate in a way that is strategic by having partnerships and relationships with all the players, I suppose, in the geopolitical drama.

    ALISON BEARD: Well, it sounds like there’s actually more learning on the digital transformation front in that African companies and startups are embracing this pace of technological change, particularly with new advances in AI and analytics. So talk to me a bit about how digital transformation is helping you at Standard Bank live into your mission.

    SIM TSHABALALA: In the last 20 years at Standard Bank, we’ve invested a huge amount in our core banking system. In our case, we use SAP and Finacle, and that was necessary because we had old records of account, systems of account, and therefore we put it in SAP. That then put us in a position to be able to accelerate the speed with which we put in place systems and processes that improve the customer experience. To such an extent that I can say to you, Allison, that about 99% of our customers interface with us through digital channels. The extent to which people use physical channels is now de minimus and that we work with companies like AWS to improve the customer experience through hyperpersonalization.

    We are increasingly using predictive AI to help our frontline staff have meaningful and valuable conversations with their customers. That applies in the retail bank as much as it does in the corporate and investment bank. Our corporate investment bankers are provided with data and nudges, as it were, to have conversations with a treasurer on a particular topic if the treasurer has phoned. So that’s the predictive AI.

    On generative AI, like everybody else, we are feeling our way through this. We’re using it to improve productivity. We employ, let me just mention this, 54,000 people. Of those 54,000, 7,100 have completed online courses on AI, and that number is continuing to improve. 10,000 of our staff use our prompt library. I was making reference to the frontline and how they use hyperpersonalization, and we’ve got about 200 proof of concepts using large language models in the organization. And those proof of concepts range from risk management right across to the customer interface.

    So the summary is here on the African continent, we are at the cutting edge of digitization, whether it be in the nature of the unicorns or the fintechs, Optasia that I was referring to, or a behemoth such as Standard Bank investing heavily in digitization in order to be ready for the new frontier, the new interface with the customer.

    ALISON BEARD: Yeah. And what do you see as the right balance of tech-enabled versus human touchpoints for customers in the future? I think this is something that all consumer-facing businesses are trying to figure out right now. How far can you go on AI and what does the future workforce look like?

    SIM TSHABALALA: Alison, a frank answer from a failed lawyer who pretends to be a banker is I don’t know, but I can tell you a couple of stories that sort of point us in the right direction. We know that the industrial revolution we are going through now is in structure, form and process no different to previous revolutions. So that’s the first one.

    Machines will displace humans, but humans will find new tasks working in conjunction with machines. I’ll take you back to when the automatic teller machines were introduced. People thought that that would terminate the role of tellers, while tellers have now become consultants. When the typewriter came on stream, we all thought that it would terminate the role of secretaries. Well, secretaries are now professional assistants. The point I’m making is there will always, in our view, be a role for the empathy, the serendipity, the problem solving that is necessary from humans working in conjunction with machines. I’m in the school of thought that says, yes, AI is definitely a new frontier, but it is not going to obliterate human activity. Humans will be able to move to higher order activity.

    So for example, another example that we are working through now is you can use AI to replace analysts, for example, but that’ll release those analysts to do higher order work for which you can charge. And so my view is we will learn as we go along. We don’t quite know how it’ll look, but we do know that it’ll change the way in which we do business.

    One last thought. My last interface before joining this call was having to respond to a client complaint. And I can bet you that ChatGPT would not have been able to respond to that client. It required somebody to listen to a very angry and annoyed client, talk them through the problem and work through a solution with that client in a way that Copilot or ChatGPT would not have been able to.

    ALISON BEARD: Yeah. I’m very impressed that having a CEO on the phone to answer a customer complaint is something that Standard Bank does. So I do want to ask, you talked about the-

    SIM TSHABALALA: Just to pick up on that point – one of the things I do to make sure that I remain conscious of what is going on in the organization is I do take calls from clients from time to time. I do answer emails from time to time. Now, it’s not possible in a company that has got 16 million customers throughout the African continent for the chief executive to interface with all customers, but I do from time to time take those calls myself so that I know what I’m talking about when I complain to my colleagues about the quality of product and service delivery for example.

    ALISON BEARD: And on the same note, as you’re trying to stay in touch with the employee experience and the customer experience, you talked about re-skilling, but how are you training your workforce to operate with this mindset of adaptability and constant change? How are you bringing people on board to continue to work when the future is so uncertain?

    SIM TSHABALALA: What is certain about the future, Alison, is that the gentle art of banking will exist as it has existed for 4,000 years. So 4,000 years ago in the temples, people with excess funds or jewelry would place it with the money changer. That person would take that money and then give it to somebody else who needed it and then would make sure that they get that money back or that jewelry back to give back to the owner when the owner demanded it. They did that on top of a plank, which is where the word banker comes from. And so the point is that banking has existed for 4,000 years. There’s no reason to believe that it’ll come to an end by virtue of the new technology that is coming. So I’m in that school of thought that says the technology is going to change the way in which we interface with our customers, but the need for us to understand and give people the confidence, the trust that when we take their deposits, they will get it back, I believe will continue to exist.

    Juxtapose that against, I suppose, crypto, which is part of the major debate. One of the things cryptocurrencies do very, very well is that they remove that element of trust that has existed in the banking system and in a way that makes it anonymous and it takes it out of the banking system. I do believe that the need for people to trust in the human dimension continues to exist, notwithstanding those new developments.

    And so what do we do to train our people? We encourage them, even our tellers, to broaden their knowledge base, which is why I made reference to that library. We encourage people to train themselves. We encourage them to form part of the Copilot program that we’ve got in our bank. We encourage people to broaden their learning. We’ve got an extensive digital learning program in the bank.

    ALISON BEARD: So we have a lot of audience questions coming in, so I want to get to them. Fad Wan is asking, “Given the accelerating pace of digital transformation in African financial services, how are you balancing innovation for inclusion, such as the fintech partnerships you mentioned and the digital ecosystems with the need to protect trust, compliance, and long-term sustainabilities?” How are you scaling innovation responsibly?

    SIM TSHABALALA: This is precisely the point that I was making. So firstly, we do it making sure that we stay as close as possible to new technical developments and innovations without being at the cutting edge. So what we insist upon in our institution is that we do not want to pay first mover taxes.

    Secondly, artificial intelligence, frankly, is just a tool to meet human needs. That’s very different from saying that artificial intelligence will obliterate banking or insurance and asset management. We think of it as a tool, just like a spreadsheet that gets used to meet customer needs.

    The third one is that we spend a lot of money on it. I joke with colleagues often, to quote a former colleague of mine, that a bank or an insurance company, more importantly, a bank, is “A technology company with capital attached to it.” And so you need that technology to be able to take those deposits, advance loans, manage the risk and so forth.

    The next consideration here is that the world is a very complicated place where anti-money laundering, anti-terrorist financing, anti-proliferation programs are necessary to protect not just the financial system, but society against bad actors, and that banks are regulated tightly for that purpose in order to protect the system for its safety and soundness. So you need to have strong risk management frameworks and you need to train your staff on that.

    And lastly, and very, very importantly, to take you right back, Alison, to the question you asked me, values are actually the cornerstone of how to run a bank. We need to be certain that when we are not present, we can trust our staff to make the right decisions and do the right business the right way. And so the emphasis on values with trust, in our case, we’ve got eight values and trust is the main one.

    ALISON BEARD: So that’s related to a question that David Quandro, I hope I’m pronouncing that right, is asking about how you ensure that those beliefs, those standards, that purpose is really filtering down to the entire organization.

    SIM TSHABALALA: We use it in every single speech we make. As you’ve noticed, I’ve mentioned Africa as a home. Secondly, I’ve mentioned values as an important element of defining the culture of the organization. We take people through induction programs when they join. We get people to take programs, training, compliance training, which is compulsory for everybody, including for myself. We monitor the compliance training that people go through and we hold management to account on that compliance training. We devise our performance agreements, obviously with all the value drivers that drive an organization with conduct being an important part of that. We monitor it and we reward and penalize people on the basis of their conduct as well.

    ALISON BEARD: We have an anonymous question, but it’s related to your geographic expansion, which I really do want to dig into. So anonymous is asking, do you apply the same innovation strategy for the whole region or is it specific to each country?

    SIM TSHABALALA: So Alison, a bank grows on the basis of GDP increases, so GDP plus inflation, as well as banking penetration. So that’s the first principle. So we look around and see where’s the fastest GDP growth happening and how do we take advantage of that GDP growth?

    The second way in which you grow is by product proliferation. So you identify customer needs and then you introduce products to a particular region, a particular country to meet those needs.

    The third one is market penetration. So you identify segments that you’re not servicing. So for example, typically a bank will start serving the top end of the market, and then it’ll increasingly move into the lower end as it identifies needs in those segments at the lower end. That’s sort of the basic rubric, the basic background.

    The next thing you think about is if you see all of that growth, you decide, well, where are you going to be able to have risk adjusted returns that are acceptable? So you take the risks associated with a particular country, you think of the returns you would generate, and then you identify to what extent that particular country would meet those needs.

    What you then also do is you think carefully about striking the balance between return on equity and growth, applying the Gordon Growth Model. And then lastly, what you then do is you think through, you use Porter’s five forces to think through which niches in a particular market you ought to operate in. And you then decide then after taking all of those things into account which country, which product segment, which jurisdiction you ought to go into. Now, in our case, we’ve got small countries where, as it happens, we’re quite large and in some countries which are large where we are quite small, and you then apply portfolio theory and the Gordon Growth Model to decide where to invest given the size of the profit pools in those particular countries. I mean, that’s a long-winded way of saying there isn’t one single metric that you use to make these decisions. You apply all of them. But fundamentally, it’s about generating growth and generating return on equity.

    ALISON BEARD: And are you using artificial intelligence models internally to help you make these sort of risk management decisions?

    SIM TSHABALALA: We have introduced, as I said, we’ve got use cases in using artificial intelligence. We use some of it, we use predictive models for the purposes of doing some of our financial planning and some of our thinking, but we don’t abdicate the decision making to artificial intelligence. We’ll do the brute force and the number crunching, the heavy lifting, but we’ll always make sure that it is reviewed by humans.

    ALISON BEARD: This is also, I think, a human skill. Do CEOs like yourself, do businesses play a role in advocating for certain policies that you think will enhance sustainable growth in the markets that you’re considering entering?

    SIM TSHABALALA: Yes, we do, but we play in our lane, Alison. So I’m very, very clear about the social division of labor. We are not elected officials and we’re not politicians, but our job is to advocate for policies, laws, and regulations that make it possible and optimal for us to create prosperity. And just by way of example, I have the privilege of chairing the Finance and Infrastructure Task Force of the B20, and there we’re making a series of recommendations, which include the imperative need for the Basel standard setters to rethink the capital allocation to African projects, infrastructure projects, which are so vital to the growth and development of Africa. And that’s advocacy. There’s a need to change those rules.

    The other set of things we’re doing is we are arguing that ratings agencies misapply the data and they attribute more risk to African sovereigns than is supported by the facts and the data. And so for example, South Africa has rated BBB- by the ratings agencies. We think it should be rated BB by worth example. And the reason for that is that the default data and the default experience does not coincide with the ratings that the ratings agencies attribute to African sovereigns. And so we’re making a case for the ease of doing business, the improvement of the laws and regulations, the improvement of their risk perception premium on the African continent so that we can do more business and be doing that in the context of the G20, which is being presided over by South Africa this year.

    ALISON BEARD: We’ve had so many great questions from the audience. I want to get to just one more before we wrap up. Eric Mendoza is asking, “What are the biggest investment opportunities in Africa that the Western world is missing right now?”

    SIM TSHABALALA: Oh my word. Let’s start with on the individual side. The African population is … We’re going to have the largest population in the world by half century. We’ll have two and a half billion people. That population is getting more connected. So there are opportunities for telcos. It’s getting better educated, it’s getting healthier. Therefore, opportunities for people involved in education or health, soft infrastructure. And so there’s a demographic dividend that gives rise to massive opportunities.

    The other side of it is Africa contains the world’s largest copper deposits in the copper belt, manganese, cobalt, and indeed the rare earth minerals that are necessary for the transition. For the purposes of mining those, you need infrastructure, roads, ports, bridges. All of these need to be built. So you have the Lobito Corridor, you have the Port of Dar es Salaam, or you have the [inaudible 00:31:16] Corridor. Massive opportunity to invest in these and generate a return far superior to the risks that are taken by being invested in those projects.

    ALISON BEARD: That’s Sim Tshabalala, the CEO of Standard Bank, speaking to me as part of HBR’s Future of Business conference. Check in next Thursday for another CEO interview from the event.

    If you found this episode helpful, share it with a colleague and be sure to subscribe and rate IdeaCast in Apple Podcasts, Spotify, or wherever you listen. If you want to help leaders move the world forward, please consider subscribing to Harvard Business Review. You’ll get access to the HBR mobile app, the weekly exclusive insider newsletter and unlimited access to HBR online. Just head to hbr.org/subscribe.

    Thanks to our team, senior producer Mary Dooe, audio product manager Ian Fox and senior production specialist Rob Eckhardt, and thanks to you for listening to the HBR IdeaCast. We’ll be back with a new Future of Business episode on Thursday. I’m Alison Beard.

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  • UAE Central Bank Issues New Central Bank Law Consolidating Financial Sector Regulation

    UAE Central Bank Issues New Central Bank Law Consolidating Financial Sector Regulation

    Client Alert  |  November 13, 2025


    This update summarises the most significant reforms introduced by the New CBUAE Law and the implications for financial institutions operating in the UAE.

    On 15 September 2025, the Federal-Decree Law No. 6 of 2025 Regarding the Central Bank Regulation of Financial Institutions and Activities and Insurance Business (the New CBUAE Law) was issued in the Official Gazette and became legally effective as of 16 September 2025 (Art.188). The New CBUAE Law repeals and replaces both Federal Decree Law No. 14 of 2018 (the “2018 Law), which previously governed the Central Bank of the United Arab Emirates (CBUAE) and onshore financial institutions, and Federal Decree Law No. 48 of 2023, which regulated insurance activities.

    The New CBUAE Law represents a significant overhaul of the financial regulatory framework of the United Arab Emirates (UAE). It consolidates the regulation of banks, payment service providers, and insurers under a single legislative umbrella, introduces new licensing requirements for emerging-technology providers, and imposes enhanced penalty and enforcement provisions.

    We have summarised below the most significant reforms introduced by the New CBUAE Law and the implications for financial institutions operating in the UAE.

    Criminal Sanctions Introduced for Unlicensed Financial Activities

    Under the 2018 Law, the prohibition on carrying out financial activities without a license lacked corresponding sanctions. While the previous law established that no person could engage in regulated financial activities without a license from the CBUAE, it did not specify criminal penalties for breaches. The New CBUAE Law addresses this and the approach is now consistent with what we see in other jurisdictions, where engaging in regulated financial activities without authorisation constitutes a criminal offence.

    Article 60 reaffirms the general prohibition on conducting any regulated activities without an appropriate license. It provides that only persons or entities duly licensed in accordance with the Law, together with its implementing regulations and decisions, may engage in or offer such activities within the State.

    The key development lies in Article 170, which now expressly criminalises the conduct of carrying out unlicensed financial activities. Article 168 provides that, without prejudice to other penalties or measures, the CBUAE may impose administrative penalties and fines where a person is engaged in any of the activities specified in the law without a license.

    Article 170 introduces a new criminal penalty for such conduct. Persons that engage in a licensed financial activity without a license may face imprisonment and/or a fine between AED 50,000 and AED 500 million, representing a significant increase over the penalties available under the 2018 Law. This is a notable development, and we may see increased enforcement in light of this new framework.  Importantly, this change reflects the UAE’s commitment to strengthening the deterrent framework for unlicensed financial activities.

    The prohibition on engaging in financial activities without a license applies to those entities operating outside the UAE and to those operating in the financial free zones such as the Dubai International Finance Centre and Abu Dhabi Global Market. Accordingly, any firm targeting UAE retail customers — even if licensed by a financial free zone regulator— may be subject to criminal sanctions under the Federal framework. Pursuant to Article 4 of Federal Decree Law No. 8 of 2004 such financial free zones remain subject to all federal laws (with the exception of federal civil and commercial laws) and the New CBUAE Law shall take precedence in the event of any conflict.

    Express Prohibition on Unlicensed Communications Extends CBUAE’s Regulatory Perimeter

    The New CBUAE Law also introduces some entirely new provisions, one of which is an express prohibition on conducting, or communicating in relation to, licensed financial activities without proper authorisation. This is a significant development that materially broadens the CBUAE’s regulatory perimeter to include promotional and marketing communications directed at UAE residents.

    By virtue of Article 61(1)(h), advertising, marketing or promoting a licensable financial activity is expressly defined as a licensed financial activity in its own right. Accordingly, any person engaging in such activities must hold an appropriate license from the CBUAE. Article 60(3) reinforces this principle by stipulating that licensed financial activities and products may only be offered or conducted from within the UAE in compliance with the provisions of the Law and its implementing regulations.

    The New CBUAE Law defines “communication” broadly, encompassing any form of communication or invitation, including by telephone, fax, email, internet or mobile phone, as well as invitations to enter into or conclude transactions relating to licensed activities.

    Given this expansive definition, the New CBUAE Law captures not only conduct taking place within the UAE, but also communications made from abroad to persons in the UAE. As a result, unlicensed foreign firms that market or promote financial products or services to UAE residents, whether through online platforms or other digital means, now fall within the regulatory perimeter and risk breaching the New CBUAE Law’s prohibitions. Firms operating outside the UAE should therefore assess whether their remote or online communications could constitute the carrying on of a licensed activity into the State and whether local licensing or authorisation is required.

    Regulatory Perimeter Extended to Virtual Assets and Facilitation of Decentralised Platforms

    Another entirely new provision is Article 62, which expands the CBUAE’s regulatory perimeter to capture activities conducted through emerging technologies, including virtual assets and decentralised finance (DeFi) models.

    Article 62 extends the scope of the licensing framework by providing that, subject to existing licensed activities, any person who engages in, offers, issues, or facilitates a licensed financial activity – by any means or through any medium – is subject to the licensing, regulatory, and supervisory authority of the CBUAE.

    Importantly, this goes beyond simply prohibiting the carrying out of regulated activities without a license; it now expressly captures the facilitation of such activities, either directly or indirectly. This means that entities providing technological infrastructure, platforms, protocols, or digital tools that enable or support the delivery of financial services may themselves fall within the regulatory perimeter, even if they do not directly offer the underlying financial products or services.

    By explicitly capturing facilitation, the New CBUAE Law ensures that firms cannot avoid regulatory oversight by characterising themselves solely as technology providers. Going forward, technology companies, payment processors, and DeFi operators will need to evaluate whether their business models could be deemed to facilitate licensed activities and therefore trigger a licensing requirement under the new framework.

    Expanded Obligations for Licensed Financial Institutions (LFIs)

    The New CBUAE Law also sets out an integrated framework of prudential, conduct, and consumer protection obligations for all LFIs.

    Under Articles 114 and 130, LFIs must comply with all regulations, standards, and circulars issued by the CBUAE, including those governing capital adequacy, liquidity, governance, risk management, and related-party exposures. The CBUAE has authority to issue detailed governance and fit-and-proper rules for board members and senior management, strengthening accountability and oversight across the sector. The New CBUAE Law makes clear that the CBUAE may take all necessary measures and procedures and use all means necessary to ensure the proper functioning of LFIs.

    On the conduct side, Articles 148 through 152 introduce a dedicated consumer protection regime, requiring LFIs to handle customer complaints through independent channels, maintain transparent product disclosures, implement anti-fraud measures, and promote financial literacy and inclusion.

    Articles 183 and 184 confirm that during the transitional period, existing prudential and conduct regulations issued under the repealed 2018 Law continue to apply until replaced, ensuring regulatory continuity while the CBUAE phases in new standards under the updated framework (please refer to “Transitional Provisions and Legal Continuity” below).

    Enhanced Resolution and Recovery Framework

    Articles 142 through 146 of the New CBUAE Law introduce a comprehensive resolution and recovery regime for LFIs and insurers, positioning the UAE in line with leading international standards on financial stability and systemic risk mitigation. Under these provisions, the CBUAE is empowered to intervene early in cases of financial distress, impose corrective measures, and, where necessary, initiate resolution proceedings through a newly established Settlement and Resolution Authority. The framework provides the CBUAE with extensive tools, ranging from management replacement and capital restructuring to the transfer or sale of assets and liabilities, in order to ensure the orderly continuity of critical functions and protect depositors and policyholders. Article 144 codifies a clear creditor priority and loss allocation system whilst Articles 145 to 146 establish transparency obligations and oversight until full wind down. Any resolution, dissolution, or liquidation decision requires public notification through official channels, including publication in the Official Gazette and local newspapers, with a minimum three-month notice period to allow customers and creditors to safeguard their interests. The provisions also mandate the appointment and disclosure of the designated resolution or liquidation administrator, who is responsible for implementing the resolution plan and coordinating with affected stakeholders. The CBUAE retains supervisory authority over institutions throughout the resolution and liquidation process.

    Collectively, these reforms mark a major step toward a risk based, internationally aligned resolution framework that underpins confidence in the UAE’s financial system.

    Enforcement and Settlement

    The New CBUAE Law introduces, for the first time, a negotiated settlement mechanism within the CBUAE’s enforcement framework. Under Article 168(6), the CBUAE may, at its discretion, enter into settlements with regulated entities or individuals in respect of administrative penalties and fines, in accordance with procedures and regulations to be issued in due course. We expect that the implementing regulations (once issued) will set out the criteria, documentation, and approval process for such settlements.

    This provision creates a formal legal basis for the CBUAE to resolve supervisory breaches through proportionate, risk-based settlements, rather than solely through the imposition of fixed penalties. The new approach aligns the UAE’s enforcement framework with international best practice, allowing the regulator to recognise cooperation, remedial action, and the scale of impact when determining outcomes, while still preserving regulatory deterrence.

    Transitional Provisions and Legal Continuity

    Articles 183 to 185 of the New CBUAE Law establish a clear framework to ensure regulatory continuity and an orderly transition from the repealed legislation. All regulations, circulars, guidelines and decisions issued under the previous frameworks shall remain in full force and effect until expressly replaced by new instruments issued under the New CBUAE Law, with existing definitions and technical terms retaining their meaning during the interim period. Regulated institutions must regularise their position within one year from the Law’s effective date to align with the new requirements (although note that this one year period is extendable at the CBUAE’s discretion). At the same time, any provisions under the old framework that are inconsistent with the New CBUAE Law are repealed.

    Collectively, these articles safeguard legal certainty and market stability while the CBUAE implements the new regulatory framework and issues updated prudential and conduct regulations.

    Conclusion

    Entities captured under the New CBUAE Law have one year from 16 September 2025 to bring their operations into compliance, and this one year may be extended as CBUAE deems appropriate. The new framework marks a significant shift in the UAE’s regulatory landscape, underscoring that the CBUAE and UAE authorities are taking enforcement and supervision seriously across all segments of the financial sector, ranging from unlicensed financial activities to emerging technologies.

    If you have any concerns about how the New CBUAE Law may affect your business, please contact your regular Gibson Dunn advisor or any member of our UAE team.


    The following Gibson Dunn lawyers prepared this update: Renad Younes, Mohammed Bashir, Sameera Kimatrai, Aliya Padhani, and Holly Alderton.

    Gibson Dunn’s lawyers are available to assist in addressing any questions you may have regarding these developments. If you wish to discuss any of the matters set out above, please contact any member of Gibson Dunn’s Financial Regulatory team, including the following members in Dubai:

    Sameera Kimatrai (+971 4 318 4616, skimatrai@gibsondunn.com)

    Aliya Padhani (+971 4 318 4625, apadhani@gibsondunn.com)

    © 2025 Gibson, Dunn & Crutcher LLP.  All rights reserved.  For contact and other information, please visit us at www.gibsondunn.com.

    Attorney Advertising: These materials were prepared for general informational purposes only based on information available at the time of publication and are not intended as, do not constitute, and should not be relied upon as, legal advice or a legal opinion on any specific facts or circumstances. Gibson Dunn (and its affiliates, attorneys, and employees) shall not have any liability in connection with any use of these materials.  The sharing of these materials does not establish an attorney-client relationship with the recipient and should not be relied upon as an alternative for advice from qualified counsel.  Please note that facts and circumstances may vary, and prior results do not guarantee a similar outcome.

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  • Tiny robots swim through blood, deliver drugs — and then dissolve

    Tiny robots swim through blood, deliver drugs — and then dissolve

    The tiny, drug-filled robots are guided through blood vessels using magnets.Credit: Luca Donati/lad.studio Zürich

    A remote-controlled robot the size of a grain of sand can swim through blood vessels to deliver drugs before dissolving into the body. The technology could allow doctors to administer small amounts of drugs to specific sites, avoiding the toxic side effects of body-wide therapies.

    The microrobots — guided by magnetic fields — work in blood vessels in pigs and sheep, researchers showed in a paper published in Science on 13 November1.

    The system has yet to be trialled in people, but it shows promise because it works in a roughly human-sized body, and because all its components have already been shown to be biocompatible, says Bradley Nelson, a mechanical engineer at Swiss Federal Institute of Technology (ETH) in Zurich, who co-led the work.

    Around one-third of developed drugs that fail to come to market do so because they’re too toxic2, says Nelson. The team says the microrobots would allow smaller amounts of drugs to be given directly to the affected areas, thereby reducing potential side effects. The technique could be used to target stroke-causing blockages or brain tumours.

    “The demonstrations are compelling but still preclinical,” says Wei Gao, a medical engineer at the California Institute of Technology in Pasadena, whose team has developed an alternative robotic drug-delivery system. But if further studies proceed smoothly, remote-controlled drug-delivery robots could be used in the first medical applications within five to ten years, he says.

    A looping animated sequence showing an insertion catheter with a gripper arm releasing a microrobot into a clear demonstration replica of a human vein.

    Credit: ETH Zürich

    Robot-delivered drugs

    Researchers have explored how to use tiny robots to deliver drugs for decades, including by steering them using ultrasound and using rotating devices that mimic bacteria.

    The system developed by the ETH team involves filling a tiny bead of gelatine with a drug, as well as nanoparticles of magnetic iron oxide, which allows its movement to be controlled by magnetic fields surrounding the patient.

    In trials in the brains of pigs and sheep, the team showed that they could use a catheter to insert the bots, before making them roll along the edges of blood vessels, swim against the flow or navigate with the stream at speeds as fast as 40 centimetres per second. They used X-ray images to observe and manoeuvre the bots in real time with millimetre-precision. In trials in pigs, the team showed that in more than 95% of cases, the drugs were delivered to the correct location.

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  • Enel ups guidance on 2025 net income, plans data centres – Reuters

    1. Enel ups guidance on 2025 net income, plans data centres  Reuters
    2. Enel’s 9-month profit rises to €5.7 bn, Italy margins down (2)  ANSA
    3. Italy’s Enel ups guidance on full-year net income  Global Banking And Finance Awards®
    4. Enel, net profit down 11% in nine months, offsets decline in Italian margins with foreign operations, improves 2025 guidance  MarketScreener
    5. Enel’s 9-month profit rises to €5.7 bn, Italy margins down  ANSA

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  • Fed's Hammack says restrictive monetary policy needed to cool inflation – Reuters

    1. Fed’s Hammack says restrictive monetary policy needed to cool inflation  Reuters
    2. Fed’s Hammack: Worried about the labor market  Forex Factory
    3. The U.S. official who is most serious about fighting inflation is in Cleveland  MarketWatch
    4. Investors are weighing comments from Federal Reserve officials stating the case for fighting elevated inflation  themercury.com
    5. Fed’s Hammack: Politics plays no role in setting monetary policy  FXStreet

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  • CrowdStrike Named an Inaugural Google Unified Security Recommended Partner

    CrowdStrike Named an Inaugural Google Unified Security Recommended Partner

    Google Cloud Security selects CrowdStrike as an inaugural partner for unifying endpoint, identity, cloud, and data protection across hybrid and multi-cloud environments

    AUSTIN, Texas – November 13, 2025 – CrowdStrike (NASDAQ: CRWD) today announced that it was named one of three inaugural partners in the Google Unified Security Recommended program, recognizing the AI-native CrowdStrike Falcon® platform for endpoint protection. CrowdStrike is the only inaugural endpoint technology selected by Google for the Unified Security Recommended program.

    The Recommended program recognizes the breadth and depth of Google Cloud-validated integrations between the Falcon platform, Google Security Operations, Google Threat Intelligence, and Chrome Enterprise that enable customers to detect, investigate, and respond to threats faster. The collaboration also supports integrations that secure the AI lifecycle – and extends through the Model Context Protocol (MCP) to advance AI for security operations. Together, CrowdStrike and Google Cloud deliver unified protection across endpoint, identity, cloud, and data across hybrid and multi-cloud environments, accelerating the market’s shift to consolidate security investments onto a single, AI-powered cybersecurity platform.

    CrowdStrike and Google Cloud continue to innovate to help organizations stop breaches and secure innovation in the cloud. Customers benefit from Mandiant Incident Response and Mandiant Threat Defense services with the Falcon platform and Google Cloud Security Operations, along with joint integrations that enable end-to-end security for AI innovation.

    “CrowdStrike pioneered modern endpoint protection and built the cybersecurity platform trusted by the world’s leading organizations and hyperscalers,” said Daniel Bernard, chief business officer, CrowdStrike. “Google Cloud’s recognition reinforces CrowdStrike’s market leadership in endpoint, delivering the outcome of stopping breaches. The AI era demands collaboration across an open ecosystem, and together with Google Cloud we’re delivering the speed, intelligence, and trust organizations need.”

    “Through the Google Unified Security Recommended program, we’re partnering with trusted leaders like CrowdStrike to help customers strengthen their defenses with unified, AI-driven protection,” said Chris Corde, senior director of product management, Google Cloud. “CrowdStrike’s integrations with Google Cloud products and services and commitment to open innovation exemplify what this program was built for – helping enterprises achieve better security outcomes and protect every environment from endpoint to cloud.”

    CrowdStrike and Google Cloud are helping to redefine how organizations secure the cloud – advancing an open future for security and delivering unified protection for joint customers.

    For more information on the CrowdStrike-Google Cloud partnership, visit here.

    About CrowdStrike

    CrowdStrike (NASDAQ: CRWD), a global cybersecurity leader, has redefined modern security with the world’s most advanced cloud-native platform for protecting critical areas of enterprise risk – endpoints and cloud workloads, identity and data.

    Powered by the CrowdStrike Security Cloud and world-class AI, the CrowdStrike Falcon® platform leverages real-time indicators of attack, threat intelligence, evolving adversary tradecraft and enriched telemetry from across the enterprise to deliver hyper-accurate detections, automated protection and remediation, elite threat hunting and prioritized observability of vulnerabilities.

    Purpose-built in the cloud with a single lightweight-agent architecture, the Falcon platform delivers rapid and scalable deployment, superior protection and performance, reduced complexity and immediate time-to-value.

    CrowdStrike: We stop breaches.

    Learn more: https://www.crowdstrike.com/

    Follow us: Blog | X | LinkedIn | Instagram

    Start a free trial today: https://www.crowdstrike.com/trial

    © 2025 CrowdStrike, Inc. All rights reserved. CrowdStrike and CrowdStrike Falcon are marks owned by CrowdStrike, Inc. and are registered in the United States and other countries. CrowdStrike owns other trademarks and service marks and may use the brands of third parties to identify their products and services.

    Media Contacts

    Jake Schuster

    CrowdStrike Corporate Communications

    press@crowdstrike.com

     



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