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Category: 3. Business
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Asian Currencies Consolidate Ahead of Key U.S. Economic Data – The Wall Street Journal
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Assessing China’s overseas coal power ban – Centre for Research on Energy and Clean Air
More than four years after President Xi Jinping pledged to end China’s financing of overseas coal projects, the annual assessment from the Centre for Research on Energy and Clean Air (CREA) and the People of Asia for Climate Solutions (PACS) finds that while some progress has been made, the rise of privately owned off-grid captive coal projects for industrial needs, particularly in Indonesia and Africa, is a growing concern.
While many coal plants have been cancelled, others continue to move forward, especially privately funded, off-grid projects for industrial use, revealing that implementation gaps and loopholes persist.
The assessment analyses five categories — cancelled; pre-permitted; permitted; under construction; operational — and adds a new project category that has emerged this year for idle plants that could return to service at any time without entering a formal permitting process: mothballed.
As of July 2025, the total capacity of overseas coal projects in the pipeline has dropped to 31.4 gigawatts (GW), down from nearly 50 GW in 2024. Cancellations have also accelerated, after a slowdown in 2024, with 16.4 GW of new capacity cancelled in 2025. Since the 2021 pledge, a total of 59.3 GW of projects have been cancelled, which is equivalent to 6.1 billion tonnes of avoided lifetime carbon dioxide (CO₂) emissions.
Despite these positive trends, operational projects have grown by 4.1 GW in 2025. Most of these projects were under construction in 2024 or about to be commissioned, demonstrating that once a plant enters the construction stage, it is unlikely to be cancelled.
Trends in China-backed overseas coal power: 2021 to 2025 Q3 Although the pace of construction has slowed in 2025, 12.1 GW of capacity remains under construction across 14 projects. These consist largely of captive coal projects in Indonesia, India, Laos, Zimbabwe, and Zambia. These are off-grid facilities that serve industrial needs and are owned by private Chinese companies. This loophole casts a growing shadow over the progress made in ending China’s overseas coal investments. See report annex for further details in the field studies.
To-date, China’s overseas captive coal projects have added an estimated 1.5 billion tonnes of lifetime CO₂, which comes to almost half of all emissions currently in operation. The current projects under construction could add a total of around 3.4 billion tonnes of potential lifetime CO₂ emissions upon completion.
Policy recommendations
CREA and PACS propose the following policy recommendations to expedite the implementation of President Xi’s 2021 pledge to phase-out China-backed overseas coal projects, including but not limited to:
- The pledge should explicitly cover captive coal. Approvals and financing should require renewable or hybrid alternatives, best available technology (BAT), environmental standards, and time-bound retirement plans.
- The prioritisation of financing redirected towards renewable energy investments: solar, wind, hydro, storage, and grid modernisation. In host countries with pre-permit projects, targeted support for project preparation, land and transmission access, and power market reforms can accelerate renewable pipelines and reduce coal dependence.
- Support for host country transition strategies. China and international partners should expand technical and financial assistance for national transition plans, cooperating with local authorities to help ensure that the shift away from coal also supports economic resilience and local employment.
- Establishing a dedicated coordinating agency. Since the 2021 pledge, China has yet to designate a body responsible for its enforcement. A dedicated agency with strong coordination and regulatory powers is needed to guide implementation, ensure accountability, and intervene in irresponsible or illegal operations when necessary.
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Gold Falls on Reports of China’s Finance Ministry Ending Tax Incentive for Gold Sales – The Wall Street Journal
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Hyundai Motor Group Partners With EDB To Build up Capabilities in Low-Carbon Technologies, Including Hydrogen
- Hyundai Motor Group signs Memorandum of Understanding with Singapore’s Economic Development Board to identify partnership opportunities in building up capabilities in low-carbon technologies such as hydrogen
- Collaboration reinforces Hyundai Motor Group’s commitment to advancing hydrogen technologies and supporting Singapore’s efforts to drive low-carbon hydrogen innovation
SEOUL, November 2, 2025 – Hyundai Motor Group (the Group) has signed a Memorandum of Understanding (MoU) with the Economic Development Board (EDB) of Singapore to identify opportunities to develop low-carbon technologies, including hydrogen.The initiative builds on the existing partnership between the Group and EDB through the Hyundai Motor Group Innovation Center Singapore (HMGICS), which is Hyundai Motor Group’s first global open innovation hub and testbed.
Recognizing Singapore’s ambitions set out in the Green Plan 2030, the Group is exploring various potential collaborations with Singapore-based companies and start-ups including the potential use of Singapore’s pipeline network for efficient hydrogen distribution, aiming to address logistical challenges and enhance resource efficiency.
Through this collaboration, the Group reaffirms its commitment to advancing hydrogen as a clean energy source.
“We are excited to collaborate with the EDB to explore new growth areas, including the development of low-carbon technologies,” said Jaeha Park, Vice President, Head of Global Hydrogen Business Sub-Division at Hyundai Motor Group. “By bringing our cutting-edge expertise in hydrogen technology, this partnership represents a significant step forward in creating a clean energy future for Singapore. We look forward to driving impactful solutions that demonstrate the potential of hydrogen as a cornerstone of global sustainability.”
EDB will facilitate HMG’s participation in relevant initiatives to build up and apply low-carbon technologies, including potential collaborations with local enterprises and innovation partners to drive technological advancement.
“This MoU builds on the strong partnership between EDB and Hyundai Motor Group. The collaboration is closely aligned to Singapore’s commitment to develop a low-carbon economy, by supporting companies on sustainable technology development. This will strengthen Singapore’s position as a global innovation hub within Hyundai Motor Group’s global network,” Zheng Jingxin, Vice President and Head of Mobility at the Singapore Economic Development Board.
The Group’s mid-to-long-term vision extends globally, as it looks to expand the clean hydrogen ecosystem by integrating eco-friendly energy businesses across neighbouring countries. By focusing on sustainable energy solutions and advanced infrastructure, the Group continues to lead the way in hydrogen energy innovation, setting new benchmarks for global sustainability.
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About Hyundai Motor Group
Hyundai Motor Group is a global enterprise that has created a value chain based on mobility, steel, and construction, as well as logistics, finance, IT, and service. With about 250,000 employees worldwide, the Group’s mobility brands include Hyundai, Kia, and Genesis. Armed with creative thinking, cooperative communication, and the will to take on any challenges, we strive to create a better future for all.More information about Hyundai Motor Group can be found at: http://www.hyundaimotorgroup.com or Newsroom: Media Hub by Hyundai, Kia Global Media Center (kianewscenter.com), Genesis Newsroom
Contact:
Jihyun Park
Global PR Strategy & Planning / Hyundai Motor Group
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Dual abstinence from nicotine vaping and cannabis use among young people: secondary analyses from two U.S.-based randomized controlled trials of vaping cessation | Substance Abuse Treatment, Prevention, and Policy
Among 1,503 adolescents randomized, the 7-month follow-up rate was 70.8% (n = 1,064). Data on cannabis use was missing for 48 participants, who provided data only on 7-month nicotine vaping status. Thus, the adolescent analytic sample comprised n = 1,016 participants with follow-up data on both e-cigarette and cannabis use. There was no differential attrition by treatment assignment (p = 0.20), with 66.0% (501 of 759) of Intervention participants retained at 7 months versus 69.2% (515 of 744) of Control. Likewise, there was no differential attrition by baseline cannabis use (p = 0.74), with 68.4% (258 of 377) of Exclusive E-cigarette Users retained at 7 months versus 67.3% (758 of 1126) of Dual Users. At baseline, 74.6% (95% CI = 71.8, 77.3) of adolescents reported past 30-day cannabis use, which decreased to 50.1% (47.0, 53.2) at 7 months, a 24.5% point change (95% CI = 20.8, 28.0; McNemar’s test p < 0.001).
Among 2,588 YAs randomized, the 7-month follow-up rate was 76.0% (n = 1,967). Data on cannabis use was missing for 138 participants, who provided data only on 7-month nicotine vaping status. Thus, the YA analytic sample comprised n = 1,829 participants with follow-up data on both e-cigarette and cannabis use. There was no differential attrition by treatment assignment (p = 0.14), with 69.3% (904 of 1304) of Intervention participants retained at 7 months versus 72.0% (925 of 1284) of Control. Likewise, there was no differential attrition by baseline cannabis use (p = 0.86), with 70.9% (747 of 1053) of Exclusive E-cigarette Users retained at 7 months versus 70.5% (1,082 of 1534) of Dual Users. At baseline, 59.2% (95% CI = 56.9, 61.4) of YAs reported past 30-day cannabis use, which decreased to 55.0% (95% CI = 52.7, 57.3) at 7 months, a 4.2% point change (95% CI = 1.9, 6.4; McNemar’s test p < 0.001).
What were the overall patterns of abstinence from e-cigarettes and cannabis at 7-months?
As shown in Table 1, 31.7% (95% CI = 28.8, 34.6) of adolescents were Dual Abstinent, 18.2% (95% CI = 15.9, 20.7) were Exclusive E-cigarette Users, 15.1% (95% CI = 12.9, 17.4) were Exclusive Cannabis Users, and 35.0% (95% CI = 32.1, 38.1) were Dual Users.
Table 1 Dual use of nicotine e-cigarettes and cannabis at 7 months by treatment assignment and baseline product use among adolescents (13–17 years) enrolled in a randomized trial of vaping cessation, n (%) As shown in Table 2, 15.6% (95% CI = 13.9, 17.3) of YAs were Dual Abstinent, 29.4% (95% CI = 27.3, 31.6) were Exclusive E-cigarette Users, 12.8% (95% CI = 11.3, 14.5) were Exclusive Cannabis Users, and 42.2% (95% CI = 39.9, 44.5) were Dual Users.
Table 2 Dual use of nicotine e-cigarettes and cannabis at 7 months by treatment assignment and baseline product use among young adults (18–24 years) enrolled in a randomized trial of vaping cessation, n (%) Was there a treatment effect in promoting dual abstinence at follow-up?
Yes. As shown in Table 1, among adolescents, the rate of Dual Abstinence was 13.5% points higher (95% CI = 7.8, 19.1; p < 0.0001) among those randomized to Intervention (38.5%; 95% CI = 34.4, 42.9) vs. Control (25.0%; 95% CI = 21.5, 29.0). As shown in Table 2, among YAs, the rate of Dual Abstinence was 4.6% points higher (95% CI = 1.3, 7.9; p = 0.007) among those randomized to Intervention (17.9%; 95% CI = 15.5, 20.6) vs. Control (13.3%; 95% CI = 11.2, 15.7).
Did treatment effects in promoting dual abstinence vary by baseline product use?
No. In the adolescent sample, the treatment advantage of Intervention over Control was comparable for Exclusive E-cigarette Users (12.4 points; 95% CI = 0.6, 23.8) and Dual Users (13.9 points; 95% CI = 7.4, 20.3), interaction p = 0.82 (Table 1). Among Exclusive E-cigarette Users, 44.0% of adolescents randomized to Intervention were Dual Abstinent (95% CI = 35.1, 53.1) compared to 31.6% of Control (95% CI = 23.8, 40.2). Among Dual Users, 36.7% of Intervention participants were Dual Abstinent (95% CI = 31.8, 41.8) compared to 22.8% of Control (95% CI = 18.7, 27.3).
Likewise, in the YA sample, the treatment advantage of Intervention over Control was comparable for Exclusive E-cigarette Users (7.4 points; 95% CI = 1.1, 13.7; p = 0.02) and Dual Users (3.7 points; 95% CI = 0.0, 7.1, p = 0.03), interaction p = 0.28 (Table 2). Among Exclusive E-cigarette Users, 29.7% of YAs randomized to Intervention were Dual Abstinent (95% CI = 25.0, 34.8) compared to 22.3% of Control (95% CI = 18.3, 26.8). Among Dual Users, 10.3% of Intervention participants were Dual Abstinent (95% CI = 7.9, 13.2) compared to 6.6% of Control (95% CI = 4.6, 9.0).
Was there an interaction effect between vaping status at 7 months and baseline tobacco product use on cannabis use outcomes?
Among adolescents, the difference in cannabis use at follow-up between continuing vapers and vaping abstainers was significantly weaker among baseline Exclusive E-cigarette Users than among baseline Dual Users (interaction p < 0.001). As shown in Supplemental Table 1, among 258 adolescent baseline Exclusive E-cigarette Users, cannabis use at 7 months was reported by 31.1% (95% CI = 23.4, 39.6) of those who were still nicotine vaping versus 21.1% (95% CI = 14.8, 29.2) of those who were vaping abstinent, a 10% point difference (95% CI = −0.8, 20.3). Among 758 baseline Dual Users, cannabis use at 7 months was reported by 77.3% (95% CI = 72.9, 81.3) of those who were still nicotine vaping versus 36.1% (95% CI = 31.1, 41.3) of those who were vaping abstinent, a 41.3% point difference (95% CI = 34.5, 47.4). In total, 97 out of 258 baseline Exclusive E-cigarette Users were dual abstinent (37.6%) compared to 225 out of 758 baseline Dual Users (29.7%), a significant difference at p = 0.019.
Among YAs, the difference in cannabis use at follow-up between continuing vapers and vaping abstainers was comparable (interaction p = 0.81) for baseline Exclusive E-cigarette Users and baseline Dual Users. As shown in Supplemental Table 2, among 747 YA baseline Exclusive E-cigarette Users, cannabis use at 7 months was reported by 27.2% (95% CI = 23.4, 31.2) of continuing nicotine vapers versus 16.8% (95% CI = 12.2, 22.3) of vaping abstainers, a 10.4% point difference (95% CI = 3.9, 16.2, p < 0.001). Among 1,082 baseline Dual Users, cannabis use at 7 months was reported by 79.5% (95% CI = 76.5, 82.2) of continuing nicotine vapers versus 68.1% (95% CI = 62.3, 73.4) of vaping abstainers, an 11.4% point difference (95% CI = 5.5, 17.6). In total, 193 out of 747 baseline Exclusive E-cigarette Users were dual abstinent (25.8%) compared to 92 out of 1082 baseline Dual Users (8.5%), a significant difference at p < 0.001.
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Feed One Ltd. (TSE:2060) Margin Decline Challenges Reputation for Reliable Growth
Feed One Ltd. (TSE:2060) reported net profit margins of 1.8%, down slightly from last year’s 2%, signaling some margin pressure despite a strong multi-year record. Over the past five years, the company showed robust 8.5% annual earnings growth, though the most recent period brought a decline in earnings growth compared to that trend. With shares trading at ¥1,018 and a price-to-earnings ratio of 7.5x, well below both peer and industry averages, the company stands out as attractively valued, even as near-term headwinds remain in focus.
See our full analysis for Feed OneLtd.
Next, we’ll see how these fresh results compare to the prevailing narratives. We will explore whether the new numbers reinforce the story or challenge long-held views.
Curious how numbers become stories that shape markets? Explore Community Narratives
TSE:2060 Earnings & Revenue History as at Nov 2025 -
Feed One Ltd. has delivered an 8.5% average annual earnings growth rate over the last five years, but the latest period saw earnings trend negative, marking a break from this consistent run.
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As the prevailing market view emphasizes, the company’s long-term steady performance is a draw for conservative investors. However, the slip into negative growth challenges assumptions of immunity to margin or sector pressures.
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The market acknowledges this high-quality growth track record, indicating operational reliability even as recent contractions raise questions about future resilience.
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With little excitement from the broader market, valuation optimism relies on the assumption that this downturn is temporary rather than structural.
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Risks data highlight concern over the sustainability of Feed One Ltd.’s dividend, which is currently not well supported by profits. This stands out as a key vulnerability despite its reputation for stability.
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According to the prevailing market view, the company’s image as a “safe haven” is tested since unreliable dividends can undermine investor trust in defensive stocks like this one.
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This reveals tension between the appeal of sector stability and the practical risk that dividend payouts could be cut if profitability challenges persist.
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Without a turnaround in earnings or cash generation, the main selling point for yield-focused investors may erode, making total return less attractive.
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Shares trade at ¥1,018, a steep discount to the DCF fair value estimate of ¥3,878.45 and peers’ 29.1x P/E, highlighting the market’s skepticism despite Feed One Ltd.’s much lower 7.5x multiple.
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The prevailing market view holds that such an undervaluation could be a launchpad for future upside. Yet the lack of clear earnings momentum or sector catalysts suggests the discount may persist until concrete positive developments emerge.
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While a premium could develop if Feed One Ltd. initiates strategic moves or sector conditions improve, at present, the valuation gap mainly compensates investors for ongoing margin and dividend risks.
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This makes the stock a classic value play, but patience may be required as near-term sentiment remains cautious absent new catalysts.
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Late-Breaking Clinical Trial Results Announced at The VEINS 2025
LAS VEGAS, Nov. 2, 2025 /PRNewswire/ — The VIVA Foundation, a not-for-profit organization dedicated to advancing the field of vascular medicine through education and research, today announced results from the Late-Breaking Clinical Trials presented at The VEINS 2025 conference, held at Wynn Las Vegas.
Late-Breaking Clinical Trial results were unveiled during sessions on Saturday and Sunday, November 1 and 2, showcasing new data that advance the understanding and treatment of venous disease.
The VEINS (Venous Endovascular INterventional Strategies) is a leading venous education symposium that brings together an international, multispecialty faculty to share the latest research, clinical data, and techniques in venous intervention. The program features expert presentations, interactive discussions, and data-driven sessions that inform best practices and foster collaboration across the venous community.
Results of the GORE® VIABAHN® FORTEGRA Venous Stent Clinical Trial for the Treatment of Symptomatic Inferior Vena Cava Obstruction With or Without Combined Iliofemoral Obstruction
Presented by Stephen Black, MDThe presentation entitled “Results of the GORE® VIABAHN® FORTEGRA Venous Stent Clinical Trial for the Treatment of Symptomatic Inferior Vena Cava Obstruction With or Without Combined Iliofemoral Obstruction” exhibits promising results from the GORE® VIAFORT Vascular Stent Trial, evaluating the newly renamed GORE® VIABAHN® FORTEGRA Venous Stent for the treatment of deep venous obstruction.
Presented by Co-Primary Investigator Dr. Stephen Black, MD, at the VEINS Conference in Las Vegas on November 2, the trial evaluates the device’s safety and effectiveness in patients with symptomatic deep venous disease. The trial met its primary endpoint, demonstrating strong 12-month performance and reliability, reinforcing Gore’s commitment to advancing innovative solutions for complex venous conditions.
The VIAFORT Trial is the first prospective study to include the inferior vena cava (IVC), iliac, and femoral veins. Conducted across multiple international centers, the single-arm, non-randomized trial enrolled 89 patients with thrombotic disease—acute, subacute, or chronic/post-thrombotic syndrome. Notably, 94.3% of patients had lesions spanning three vessel regions, and 68.5% required stents extending below the inguinal ligament into the common femoral vein.
Despite the severity of disease, the trial achieved a 12-month primary patency rate of 83.4%. Vessel-specific patency rates were 96.5% in the IVC, 88.9% in the left iliofemoral, and 89.8% in the right iliofemoral regions. No stent migrations, fractures, vascular injuries, or clinically significant pulmonary embolisms were reported through 12 months. Additionally, there were no device-related deaths or major bleeding events within 30 days.
These results mark a significant milestone in venous stent innovation and patient care, positioning the GORE® VIABAHN® FORTEGRA Venous Stent as a reliable option for treating deep venous obstruction.
Randomized Comparison of Cyanoacrylate Closure and Endothermal Ablation: Spectrum Secondary Outcomes Through 12 Months
Presented by Manj Gohel, MDThis randomized trial was part of the Spectrum program and compared cyanoacrylate closure (CAC) with the VenaSeal system (Medtronic) to endothermal ablation (ETA) for saphenous reflux. Conducted at 17 sites across eight countries, the study enrolled participants with CEAP (clinical, etiology, anatomy, pathophysiology) C2 to C5 disease beginning in February 2020. Outcomes at 12 months included anatomic vein closure, patient and physician assessments of quality of life (QOL), safety, time to return to work, and reintervention rates.
Differences in QOL changes from baseline to follow-up visits were tested using Wilcoxon two-sample tests. Anatomic closure at 12 months was calculated with Kaplan-Meier estimates, and reintervention rates were estimated using the number of reinterventions over the target vein follow-up years. No adjustments for multiple comparisons were made for the QOL outcome tests comparing ETA and CAC, and statistical significance was not claimed for any P values.
At 7 days, improvement in the revised Venous Clinical Severity Score trended in favor of CAC (−2.2 ± 2.76) over ETA (−1.4 ± 2.51; P = .0037), and scores were comparable at 12 months (−3.9 ± 2.70 vs −3.8 ± 2.93; P = .8421). The Aberdeen Varicose Vein Questionnaire also trended in favor of CAC at 30 days (−5.4 ± 7.88 vs −2.5 ± 8.19; P = .0072) and was similar at 12 months (−8.0 ± 7.68 vs −6.6 ± 10.37; P = .0641). Vein occlusion rates through 12 months were similar between CAC (86.6%) and ETA (89.3%). No new device- or procedure-related safety events were recorded between 6 and 12 months. Hypersensitivity to CAC occurred in 5.9% (8/136) of participants, mostly self-limiting. Exit site granuloma occurred in 0.7% (one patient in the CAC group, with full resolution), and phlebitis occurred in 8.8% (CAC) versus 2.9% (ETA) patients. Ablation-related thrombus extension occurred in 0.7% (CAC) and 3.6% (ETA). Serious adverse events were rare, with none related to CAC.
Participants treated with CAC showed similar improvements in QOL to ETA. Most CAC-related safety events happen in the first 6 months after intervention. CAC is a suitable alternative to the standard of care for patients with superficial venous insufficiency.
Clinical Feasibility and Safety Study of the Use of a Novel Device for the Treatment of Chronic Venous Insufficiency of the Lower Limb
Presented by Steve Elias, MDA nonrandomized, prospective, single-center study (Salus Spitali in Tirana, Albania) enrolled 28 patients with varicose disease of the lower limbs who underwent great saphenous vein (GSV) occlusion using a novel percutaneous device deployed under ultrasound and ablation using polidocanol foam.
The primary endpoint assessed the feasibility and safety of the GSV occlusion procedure with the device, in combination with ultrasound-guided foam sclerotherapy. Safety was determined by monitoring serious adverse events related to the device within 30 days postprocedure. Feasibility was determined by completion of GSV occlusion at the end of the procedure, documented with intraoperative duplex ultrasound showing absence of any flow inside the vessel.
Secondary endpoints included GSV occlusion rates at 6 and 12 months; procedural complication rates assessed at discharge, 1 week, and 1, 6, and 12 months; assessment of pain (visual analog scale) at discharge and at 1 week; change in disease-specific quality of life (QOL) at 6 and 12 months; and change in CEAP (clinical, etiology, anatomy, pathophysiology) class at 6 and 12 months.
Results demonstrated a 100% technical success rate for deployment under ultrasound guidance, with all treated vessels occluded at the end of the procedure. The procedure was well tolerated, with no device-related adverse events. One patient experienced subfascial calf venous thrombosis at 1 week, which resolved after 10 days of heparin therapy. Preliminary follow-up data showed durable occlusion rates: GSV/small saphenous vein occlusion was achieved in 92.3% of cases at 6 months and 94.1% at 12 months; perforator occlusion was 84% at 6 months and 90% at 12 months. Patients also reported significant improvement in QOL.
Impact of Junctional Reflux on the Effectiveness of Endovenous Ablation in Patients With Great Saphenous Vein Insufficiency (JURY-2 Study)
Presented by: Yana Etkin, MDIsolated great saphenous vein (GSV) reflux without saphenofemoral junction (SFJ) involvement produces symptom severity comparable to limbs with combined SFJ plus GSV reflux, and yet many insurers still require documented SFJ reflux before approving ablation. The JURY-2 trial was designed to evaluate whether symptomatic improvement after endovenous ablation is equivalent in patients with isolated GSV reflux versus those with combined SFJ plus GSV reflux.
This prospective, multicenter cohort study enrolled adults with symptomatic CEAP (clinical, etiology, anatomy, pathophysiology) C2 to C3 venous disease and ≥ 0.5 seconds of reflux in at least two contiguous, above-knee GSV segments (with or without SFJ reflux). Patients underwent thermal or nonthermal GSV ablation with adjunct phlebectomy or sclerotherapy as needed. Symptom severity was measured by Venous Clinical Severity Score (VCSS) at baseline and 3 months postprocedure. The primary endpoint was change in VCSS, compared between groups using Welch two-sample t-tests and multivariable linear regression, adjusting for baseline VCSS and demographic/clinical covariates. Treatment outcomes were considered equivalent if the VCSS change difference was within ± 1.4 points (minimum detectable change).
Nine United States centers enrolled 252 patients (207 SFJ + GSV, 45 isolated GSV). Most were female (75%) and White (78.6%). Patients with isolated reflux were older (aged 59 vs 53 years; P = .006) and more frequently Hispanic (13.3% vs 6.3%; P < .01). Thermal ablation was used in 73% overall, more often in the combined group (77.8% vs 57.8%; P = .01). GSV closure exceeded 99% without complications. Baseline VCSS was 6.98 ± 2.24 (isolated) compared to 6.00 ± 2.16 (combined) (P = .01). At 3 months, VCSS improved to 2.58 ± 2.60 and 1.71 ± 1.87, respectively. Adjusted VCSS change scores were equivalent (–0.54 [90% CI, –1.36 to 0.27]; P = .12).
Endovenous ablation yields equivalent short-term symptom relief in limbs with isolated GSV reflux and those with combined SFJ + GSV reflux. These findings challenge reimbursement policies mandating SFJ involvement and support basing treatment eligibility based on clinical need rather than junctional anatomy.
Short-Term Cost Effectiveness of Large-Bore Mechanical Thrombectomy vs Catheter-Directed Thrombolysis for Intermediate-Risk Pulmonary Embolism From the PEERLESS Randomized Controlled Trial
Presented by: Samuel Horr, MDThe PEERLESS randomized controlled trial (RCT) provided clinical data through 30-day follow-up comparing large-bore mechanical thrombectomy (LBMT) and catheter-directed thrombolysis (CDT) for intermediate-risk pulmonary embolism (PE), but the economic implications of these outcomes remain unquantified. This study leverages findings from the PEERLESS RCT and other published literature to evaluate the short-term cost-effectiveness of LBMT versus CDT within the United States health care system.
A decision tree model simulated the clinical pathways and associated costs for a hypothetical cohort of 300,000 intermediate-risk PE patients over a 30-day period. Clinical event probabilities and resource utilization were derived from the PEERLESS RCT, while costs and quality-of-life utilities were sourced from existing literature. The primary outcomes included total costs, quality-adjusted life-years (QALYs), and net monetary benefit (NMB).
The base-case analysis demonstrated that LBMT was economically dominant, being both more effective and less costly than CDT. On a per-patient basis, treatment with LBMT was associated with an average cost savings of $4,755 and a gain of 0.009 QALYs. These savings were primarily driven by substantial reductions in intensive care unit utilization (–$6,454), the avoidance of thrombolytic drugs (–$4,068), shorter overall hospital stays (–$2,217), and fewer readmissions (–$1,134). These differences in cost and effectiveness result in an NMB of $5,211 at a willingness-to-pay threshold of $50,000/QALY. Probabilistic sensitivity analysis confirmed the robustness of this conclusion, with LBMT remaining the economically dominant strategy in 87.8% of simulations.
This economic analysis makes a strong case that for patients with intermediate-risk PE undergoing intervention, the selection of LBMT over CDT represents high economic value, resulting in both improved patient outcomes and lower total 30-day health care costs.
Comparison of Real-World Outcomes in Pulmonary Embolism Patients Undergoing Large Bore Mechanical Thrombectomy or Receiving Anticoagulation Alone: Insights From the Premier Healthcare Database
Presented by: Jay Giri, MD, MPHAlthough anticoagulation (AC) is the cornerstone of pulmonary embolism (PE) treatment, large-bore mechanical thrombectomy (LBMT) may confer additional benefits via rapid thrombus removal. Large-scale randomized evidence comparing LBMT treatment to AC alone is currently lacking. This observational study aims to address this evidence gap by comparing patient characteristics and short-term outcomes of PE patients who received either LBMT or AC alone from a large, real-world health care database.
This analysis utilized the Premier Healthcare Database, which captures approximately 25% of all inpatient discharges in the United States. We identified patients presenting with PE or with primary diagnosis of PE who underwent LBMT with the FlowTriever system (Inari Medical, now part of Stryker) (n = 5,613) or received AC alone (n = 202,199) between January 2019 and December 2023. Outcomes were statistically adjusted for demographic information, signs of acute PE severity, and standard comorbidities.
Before adjustment, LBMT patients showed signs of greater PE severity while patients receiving AC alone had a higher prevalence of chronic comorbidities. Following adjustment, LBMT was associated with significantly lower odds of in-hospital all-cause mortality (odds ratio [OR], 0.37; CI, 0.30-0.47; P < .001) and 30-day all-cause readmission (OR, 0.64; CI, 0.57-0.72; P < .001). Although associated intensive care unit (ICU) admission was more frequent in the LBMT group (OR, 5.87; CI, 5.54-6.22; P < .001), LBMT patients had a briefer associated ICU length of stay (estimate, –0.48 days; CI, –0.59 to –0.37; P < .001) among those with admissions.
This large real-world analysis indicates that acute PE patients selected for treatment with LBMT may experience improved short-term outcomes compared with those treated with AC alone. These findings justify the critical importance of actively enrolling randomized trials of acute PE intervention, including PEERLESS II.
Two-Year Clinical Outcomes From the Single-Arm Arteriovenous Graft Cohort of the WAVE Trial
Presented by: Mahmood Razavi, MDThe WAVE study is a prospective, multicenter, international trial conducted across 43 centers in the United States, South America, and the United Kingdom. This abstract focuses on the nonrandomized arm of the trial that included a single cohort of patients with an arteriovenous graft (AVG) who experienced venous outflow obstructions in their peripheral venous outflow circuit. All patients were treated with the Wrapsody Cell- Impermeable Endoprosthesis (CIE; Merit Medical Systems, Inc.). Treatment efficacy was based on the proportion of patients with target lesion primary patency (TLPP), defined as freedom from clinically driven target lesion revascularization or target lesion thrombosis. Access circuit primary patency (ACPP) was an additional efficacy measure of interest. The safety profile of the CIE was determined based on the proportion of patients without any localized or systemic safety events. Efficacy and safety results were reported throughout the 24-month follow-up period. At key time points, the efficacy and safety profiles of the CIE were compared to performance goals (6-month TLPP benchmark, 60%; 30-day safety benchmark, 89%).
A total of 112 AVG patients were enrolled. The 6-month TLPP was significantly higher than the efficacy performance goal (81.4% vs 60%; P < .0001). The proportion of patients in the AVG cohort without a safety event was significantly higher than the safety performance goal (95.4% vs 89%; P = .016). At 12 months, the TLPP was 60.2%, based on Kaplan- Meier estimate. The 6- and 12-month ACPP were 69.2% and 36.2%, respectively.
Given the limited treatment options available to restore access circuit patency, particularly for patients with dysfunctional AVG, the 24-month findings from the WAVE trial will be of interest to vascular access specialists.
About the VIVA Foundation
The VIVA Foundation, a not-for-profit organization dedicated to advancing the field of vascular medicine and intervention through education and research, strives to be the premier educator in the field. Our team of specialists in vascular medicine, interventional cardiology, interventional radiology, and vascular surgery is driven by the passion to advance the field and improve patient outcomes. Educational events presented by the VIVA Foundation have a distinct spirit of collegiality attained by synergizing collective talents to promote awareness and innovative therapeutic options for vascular disease worldwide.To learn more about the VIVA Foundation, visit https://viva-foundation.org/.
SOURCE The VIVA Foundation
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Australian Agricultural Projects Up 10%, Insider Buyers Are Up 26%
Australian Agricultural Projects Ltd (ASX:AAP) insiders who bought shares over the past year were rewarded handsomely last week. The stock rose 10%, resulting in a AU$1.8m rise in the company’s market capitalisation, translating to a gain of 26% on their initial investment. In other words, the original AU$2.00m purchase is now worth AU$2.52m.
While insider transactions are not the most important thing when it comes to long-term investing, logic dictates you should pay some attention to whether insiders are buying or selling shares.
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The Non Executive Director Daniel Stefanetti made the biggest insider purchase in the last 12 months. That single transaction was for AU$2.0m worth of shares at a price of AU$0.042 each. Even though the purchase was made at a significantly lower price than the recent price (AU$0.053), we still think insider buying is a positive. Because it occurred at a lower valuation, it doesn’t tell us much about whether insiders might find today’s price attractive.
You can see the insider transactions (by companies and individuals) over the last year depicted in the chart below. If you want to know exactly who sold, for how much, and when, simply click on the graph below!
View our latest analysis for Australian Agricultural Projects
ASX:AAP Insider Trading Volume November 2nd 2025 Australian Agricultural Projects is not the only stock that insiders are buying. For those who like to find small cap companies at attractive valuations, this free list of growing companies with recent insider purchasing, could be just the ticket.
I like to look at how many shares insiders own in a company, to help inform my view of how aligned they are with insiders. I reckon it’s a good sign if insiders own a significant number of shares in the company. Australian Agricultural Projects insiders own about AU$10m worth of shares (which is 54% of the company). This kind of significant ownership by insiders does generally increase the chance that the company is run in the interest of all shareholders.
The fact that there have been no Australian Agricultural Projects insider transactions recently certainly doesn’t bother us. On a brighter note, the transactions over the last year are encouraging. Judging from their transactions, and high insider ownership, Australian Agricultural Projects insiders feel good about the company’s future. While it’s good to be aware of what’s going on with the insider’s ownership and transactions, we make sure to also consider what risks are facing a stock before making any investment decision. For example, Australian Agricultural Projects has 4 warning signs (and 1 which can’t be ignored) we think you should know about.
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Westpac Raises Dividend Despite 1% Slip in Annual Profit — Update
By Stuart Condie
SYDNEY--Westpac raised its final dividend despite a 1.0% drop in annual profit on higher operating costs and fierce competition for deposits and loans.
Australia's third-largest bank by market capitalization on Monday reported a net profit for the 12 months through September of 6.92 billion Australian dollars, equivalent to about US$4.53 billion. It raised its final dividend to A$0.77 from A$0.76.
Revenue rose by 3.7% to A$22.38 billion, but a contraction in net interest margin and a 9.0% rise in operating expenses hit the bottom line. Costs included those supporting a multiyear technology overhaul, and A$273 million related to what the bank called productivity initiatives.
Net interest margin--a key indicator of lending profitability--fell to 1.94% from 1.95% a year ago. However, it improved over the course of the fiscal year, to 1.95% in the second half from 1.92% in the first.
The average analyst forecast had been for net profit to fall to A$6.86 billion, according to data compiled by Visible Alpha. Consensus was for revenue of A$22.26 billion and a net interest margin of 1.93%.
Mortgage lending grew by 5.0% on-year, slower than the sector as a whole. Westpac said it had agreed to sell the A$21.4 billion home-loan portfolio from its Rams subsidiary to a consortium including U.S. private-equity giant KKR & Co.
However, business lending grew by 15% on-year as Westpac refocused under Chief Executive Anthony Miller, who formerly led Westpac's business and wealth division before taking the helm in December 2024.
Analysts have flagged a broad shift by lenders toward business banking, which is seen as more profitable and less saturated than consumer banking. Westpac's business deposits rose 5.5%.
Write to Stuart Condie at stuart.condie@wsj.com
(END) Dow Jones Newswires
November 02, 2025 17:13 ET (22:13 GMT)
Copyright (c) 2025 Dow Jones & Company, Inc.
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Rolls-Royce signs skills, technology and supply chain agreement with the Victorian Government in support of AUKUS
Rolls-Royce has signed a memorandum of understanding (MOU) with the State of Victoria, Australia that outlines a commitment to collaborate on developing Victoria’s defence industry skills, supply chain, and innovation eco-system, to support the AUKUS submarine program.
Developing nuclear skills will be a particular focus, with plans to establish Rolls-Royce-affiliated skills and training academies being explored. This would build on the success of the award-winning Rolls-Royce Nuclear Skills Academy which opened in Derby, UK, in 2022. It has seen up to 200 apprentices enrolled on apprenticeships each year, creating a pipeline of nuclear talent at the start of their careers to support the UK Royal Navy.
The agreement will also look to support launching specific research and development initiatives, including the establishment of Rolls-Royce University Technology Centres and affiliated research clusters, in collaboration with Victorian universities.
Following similar agreements signed with Western and South Australian Governments in September 2025, this marks a significant step forward in Australia’s preparations for operating its first conventionally armed nuclear-powered submarines. It also highlights the unique nuclear expertise Rolls-Royce brings to the AUKUS agreement.
Victoria is at the forefront of research and innovation in Australia. The State hosts eight world-leading universities with advanced research and development capabilities. In December 2024, Victoria released its Economic Growth Statement, which backs its defence-oriented supply chain to win work, grow and support AUKUS. This includes increases in investment and trade facilitation, uplifts in small and medium-sized enterprises, workforce development initiatives, and bolstering innovation adoption.
To this aim, the collaboration agreement will also look to facilitate opportunities with Victorian small and medium enterprises, to strengthen the State’s defence supply chain and broader industrial capabilities.
Rolls-Royce has powered the UK Royal Navy’s nuclear submarines for over 65 years and is expanding its Derby site to support both UK and Australian defence programs. Rolls-Royce is the only private company in the world with the nuclear capability to manage reactor design, manufacture and decommissioning within one single entity.
In March 2023, it was confirmed that Rolls-Royce Submarines would provide all the nuclear reactor plants that will power new attack submarines as part of the tri-lateral agreement between Australia, the UK and US.
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