- FDA Clears Yartemlea for HSCT-Associated Thrombotic Microangiopathy Medical Professionals Reference
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Category: 3. Business
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FDA Clears Yartemlea for HSCT-Associated Thrombotic Microangiopathy – Medical Professionals Reference
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Solar power surplus in Spain triggers ‘discount season’ for plants
Spanish solar power is going through a shake out after a plunge in electricity prices left the owners of weak projects in one of Europe’s top renewables markets searching for exits.
The country has become a solar champion thanks to abundant sunshine and the government’s pro-renewables policies. But a surge in power production has outpaced demand, depressing electricity prices and profits for generators.
Some power producers are struggling to offload plants whose valuations have plunged as executives talk of solar “saturation”, creating a contrast between Spain and other places — China, India, Gulf states and European neighbours — where solar arrays are being built apace.
“It’s discount season,” said Carmen Izquierdo, co-founder of nTeaser, a deals marketplace. “Spain remains a dynamic market, but there is greater scrutiny of assets.”
Other producers are pivoting to installing batteries, which can complement and potentially save unprofitable solar projects.
Operational solar plants were valued at an average of €916,000 per megawatt in early 2024, but have now dropped to €648,000 per megawatt, according to nTeaser.
From 2022-24 there was a vibrant M&A market for Spanish solar portfolios, including those of mixed quality, but sellers are now having to strip out the weakest parks to close deals.
“They are willing to sacrifice part of the portfolio to move the rest forward,” Izquierdo said.
While cheap electricity is a boon for users, the gloom is even greater over so-called ready-to-build projects, where land, permits and grid access have all been secured, but construction has not begun.
A senior executive at an owner of Spanish solar plants said: “The market is flooded with ready-to-build projects that developers want to sell since they’re no longer good enough in the current market.”
Some projects were up for sale for just €1, the executive said, reflecting developers’ desperation to avoid further spending, and potential government penalties for not executing agreed construction plans.
The least attractive ready-to-build projects are often far from power grid nodes, requiring investment in expensive power lines.
As a solar downturn began in the past year, some Spanish companies sold existing plants to foreign investors. Utility group Endesa offloaded 50 per cent stakes in two solar power portfolios for a combined €1bn to Masdar, the United Arab Emirates’ state-owned clean energy company.
Prime Minister Pedro Sánchez’s Socialist-led government says cheap electricity is a good thing, and is already attracting new industrial investments that will bolster the economy.
But low prices are painful for producers. When they fall below zero, as they have for more than 500 hours in Spain this year, producers can end up having to choose between paying wholesale customers to take excess power off their hands or switching off.
Many producers insulate themselves by selling electricity through long-term power purchase agreements (PPAs), which they sign at fixed prices with corporate clients for 10-20 years.
Last month, Zelestra, an independent power producer, signed two PPAs with Microsoft in the Aragón region where the tech group plans to build data centres.
But negative prices are even clouding the market for PPAs, pulling down contract prices and prompting buyers to demand clauses that let them benefit from ultra-low rates in the spot market.
Andrés Acosta, innovation director at LevelTen Energy, a clean energy marketplace, said PPA prices that buyers are willing to pay are generally lower than what developers need — about €30 per megawatt hour — to make projects “bankable”.
“That has dramatically reduced the number of PPAs signed and means the majority of solar projects are not viable anymore unless they are hybridised with batteries,” Acosta said.
Adding battery storage to solar plants helps to limit price plunges by enabling generators to store electricity when prices drop during the day, then sell it in the evening when demand and prices are higher.
Killian Daly, executive director of Energy Tag, a non-profit group, said: “Storage should be the natural cure for the woes of the PPA market, but it’s not scaling as fast as it should do.”
The UK, Germany and Italy are far ahead of Spain in terms of existing and planned battery installations, according to data from the European Commission.
Following a nationwide blackout in Spain in April, the government took steps in November to remove some regulatory barriers to adding battery storage.
One key change eliminated a requirement for a new environmental impact assessment when installing batteries within an existing solar plant, said Pablo Martínez, Iberia lead at Modo Energy, a data provider.
That would reduce the time it takes to complete a battery project from three or four years to less than 18 months, he said.
Additional reporting by Carmen Muela in Madrid. Data visualisation by Nassos Stylianou
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AI boom adds $500bn to net worth of US tech billionaires in 2025 – Financial Times
- AI boom adds $500bn to net worth of US tech billionaires in 2025 Financial Times
- AI Minted More Than 50 New Billionaires In 2025 Forbes
- AI is creating a new billionaire class with a record number of founders under 30 The Times of India
- Would You Trust a 22-Year-Old AI Billionaire With the Global Economy? The Atlantic
- There are more self-made billionaires under 30 than ever before—11 of them have made the ultra-wealthy club in the last 3 months thanks to AI AOL.com
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Efficacy and Safety of Bisphosphonates Explored in Complex Regional Pain Syndrome
HealthDay News — Bisphosphonates may reduce complex regional pain syndrome (CRPS) pain intensity in the short term, according to a study published online Dec. 16 in Annals of Internal Medicine.
Michael C. Ferraro, from the University of New South Wales in Sydney, and colleagues conducted a systemic review and meta-analysis to examine the efficacy and safety of bisphosphonates versus placebo for CRPS. Eleven trials with 754 participants, assessing alendronate, clodronate, neridronate, pamidronate, and zoledronate, were included.
The researchers found with low certainty that in the immediate term (four weeks or less) bisphosphonates may result in little to no difference in pain intensity (mean difference [MD], −9.1 [95 percent confidence interval, −19.2 to 1.1]), while they may reduce pain intensity in the short term (more than four weeks to three months; MD, −10.0 [−18.9 to −1.1]), and result in little to no difference in pain intensity in the medium term (more than three months to six months; MD, 8.0 [−15.4 to 31.4]). Regarding the effects of bisphosphonates on pain intensity in the long term (more than six months), the evidence was very uncertain (MD, −2.5 [−19.6 to 14.6]). Bisphosphonates probably increase risk for adverse events (risk ratio, 1.1 [1.0 to 1.2]; moderate certainty).
“While this review represents the best evidence to date on treatment of CRPS, unexplained heterogeneity and limited medium- or long-term data restrict clinical application,” the authors write.
Several authors disclosed financial ties to the biopharmaceutical industry.
Abstract/Full Text (subscription or payment may be required)
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Diagnosing the innovation atmosphere of industrial parks through urban spatial perception: a multimodal large language model approach
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Dr Stanley Lai, SC recognised in Asian Legal Business Asia Top 15 Intellectual Property Lawyers 2025: Allen & Gledhill
26 December 2025We are pleased to announce that our Partner Dr Stanley Lai, SC has been named as one of Asia’s Top 15 Intellectual Property Lawyers in 2025 by Asian Legal Business.
This list highlights the achievements of Intellectual Property lawyers across Asia who have consistently delivered high-quality Intellectual Property work and set high standards in the Intellectual Property space, in addition to earning accolades from their colleagues, superiors and clients.
For more information, please click here.
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Equities open strongly, KSE-100 gains nearly 1,200 points – Business Recorder
- Equities open strongly, KSE-100 gains nearly 1,200 points Business Recorder
- Stocks hit record closing above 172,000 level Dawn
- Pakistan stocks expected to remain best-performing asset class in 2026: report Business Recorder
- PSX surges past 172k on heavyweight buying The Express Tribune
- PSX closes week at record high as KSE-100 gains over 1,500 points Profit by Pakistan
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Release of Advance GDP Estimates for Fourth Quarter 2025 – Ministry of Trade and Industry
- Release of Advance GDP Estimates for Fourth Quarter 2025 Ministry of Trade and Industry
- Market watchers raise Singapore’s 2025 GDP forecast to 4.1% in December survey Yahoo Finance Singapore
- MAS has breathing room to react to sudden shocks in 2026: economists The Business Times
- Singapore MAS survey shows economists raising 2025 growth forecast By Reuters Investing.com
- Economists raise Singapore growth forecasts for 2025, 2026 Borneo Bulletin
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China Signals Goal of Slow Yuan Gain Via Fix Well Below Estimate – Bloomberg.com
- China Signals Goal of Slow Yuan Gain Via Fix Well Below Estimate Bloomberg.com
- China’s PBOC signals caution on rapid yuan gain as it nears key 7 mark Business Recorder
- Central Parity of USD/ RMB Gains 49 bps to 7.0523 AASTOCKS.com
- The onshore yuan broke through the 7.01 mark against the US dollar, reaching a new high for 2024. Bitget
- Chinese yuan stable with upside bias in 2026: Global institutions news.cgtn.com
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Gold touches record high as rate-cut bets grow; silver hits $75 for first time
Gold prices surged to a record high in early Asian trading on Friday, buoyed by safe-haven demand and rising expectations of further interest rate cuts by the U.S. Federal Reserve.
Spot gold rose 0.5% to $4,501.44 per ounce by 0209 GMT, after touching a record peak of $4,530.60 earlier in the session.
Spot silver climbed to $75 an ounce on Friday, supported by robust industrial and investment demand, tightening inventories, geopolitical tensions and expectations of further U.S. interest rate cuts.
Silver prices rose 3.5% to $74.46 per ounce by 0229 GMT, after touching an all-time high of $75.14 earlier in the session.
Platinum jumped to an all-time high on Friday, on track for its biggest annual rise ever, as supply constraints, an unexpected EU policy U-turn on the 2035 combustion-engine ban, and shifting investor flows out of gold fuelled the rally.
Platinum prices rose 8% to an all-time high at $2,413.62 per ounce by 0304 GMT.
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