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Category: 3. Business

  • Engine failure forces United Airlines flight to return to Washington, D.C.-area airport

    Engine failure forces United Airlines flight to return to Washington, D.C.-area airport

    A United Airlines airplane is towed from a gate at Newark Liberty International Airport on August 10, 2025, in Newark, New Jersey.

    Gary Hershorn | Corbis News | Getty Images

    A United Airlines flight bound for Tokyo was forced to return to Dulles International Airport in northern Virginia on Saturday afternoon after experiencing an engine failure during departure, the Federal Aviation Administration said.

    A United spokesperson said the flight landed shortly after takeoff due to the loss of power in one engine. There were no reported injuries among the 275 passengers and 15 crew members aboard, the spokesperson said.

    Photographs and videos posted to the social media site X showed smoke billowing from near the runway at Dulles, which is located about 25 miles (40 km) from Washington, D.C., and the closest international airport to the U.S. capital.

    The FAA said it will investigate the incident on United Flight 803, which involved a Boeing 777-200 aircraft.

    A piece of the plane’s engine cover separated and caught fire, sparking a brush fire on the ground at the airport, Transportation Secretary Sean Duffy posted on X. The Metropolitan Washington Airports Authority said the fire was extinguished.

    The flight will be rescheduled for later on Saturday on a different aircraft, a United spokesperson said.

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  • Military Access, Mobility & Safety Improvement Project Week of Dec. 14, 2025 — Colorado Department of Transportation

    Military Access, Mobility & Safety Improvement Project Week of Dec. 14, 2025 — Colorado Department of Transportation

    Colorado Springs – There will be an overnight north- and southbound South Academy Boulevard lane reduction to one thru lane for each direction between Fountain Creek and Bradley Road on Wednesday, Dec. 17, 7 p.m. to 4:30 a.m. to allow crews to apply sealant to bridge expansion joints. Plan for minor delays. In case of weather impacts, a contingency night has been scheduled for Thursday, Dec. 18.

    There will be various north- and southbound South Academy Boulevard lane closures on Monday, Dec. 15 through Friday, Dec. 19, 7 a.m. to 4:30 p.m. between Venetucci Boulevard and Milton Proby Parkway to allow crews to install signage and perform remaining roadway, traffic signal and lighting work. Two lanes of traffic will be maintained in both directions. Drivers should obey posted speed limits, maintain safe following distances, and stay alert for crews and equipment in the work zone.

    Traffic Impacts

    South Academy Boulevard Widening Project

    • Overnight north- and southbound South Academy Boulevard lane reduction to one thru lane between Fountain Creek and Bradley Road on Wednesday, Dec. 17, 7 p.m. to 4:30 a.m.
    • Overnight north- and southbound South Academy Boulevard lane reduction to one thru lane between Fountain Creek and Bradley Road on Thursday, Dec. 18, 7 p.m. to 4:30 a.m. (contingency)
    • Various lane closures of north- and southbound South Academy Boulevard between Venetucci Boulevard and Milton Proby Parkway on Monday, Dec. 15 through Friday, Dec. 19, 7 a.m. to 4:30 p.m. Two lanes of traffic will be maintained. Pay attention to signage

    Project Overview

    South Academy Boulevard Widening Project
    The improvements to South Academy Boulevard in this project are located on South Academy Boulevard at the southern mile and a half of this arterial road from the I-25 interchange, crossing US 85/87, and continuing to the road’s approach to Milton E. Proby Parkway (which connects to Powers Boulevard/CO 21). Construction focuses on widening an approximately 1.5-mile section of South Academy Boulevard from two lanes to three in each direction to alleviate recurring congestion. The project includes improved drainage facilities, lighting, striping, and expanded shoulders, modified merge lanes, sound walls and bridgework. The project is expected to be complete by early 2026. This project is managed by El Paso County.

    Safety Benefits

    CDOT conducted a safety assessment for the corridor to evaluate the magnitude and nature of safety problems and analyze the causes of crashes. These transportation improvements are mitigation measures to reduce crashes, improve infrastructure, and address physical deficiencies that contribute to crashes in the corridor. Over the next 20 years, the project is estimated to result in fewer deaths, injuries and crashes on the four MAMSIP corridors.

    Project Information

    For additional information about this project:

    About the Military Access, Mobility & Safety Improvement Program Build Grant

    Colorado Department of Transportation (CDOT) has initiated a program to deliver more efficient and safer mobility along I-25, Colorado Highway 94, South Academy Boulevard, and Charter Oak Ranch Road, enabling economic stability and development. The Military Access, Mobility & Safety Improvement Program is partially funded through an $18 million BUILD grant award from the US Department of Transportation. The delivery of these improvements will strengthen and enhance the redundancy of strategic movement between the nationally significant El Paso County military installations of Fort Carson, Peterson Space Force Base, Cheyenne Mountain Space Force Station, and Schriever Space Force Base.

    Know Before You Go

    Travelers are urged to “know before you go.” Gather information about weather forecasts and anticipated travel impacts and current road conditions prior to hitting the road. CDOT resources include:

    Remember: Slow For The Cone Zone

    The following tips are to help you stay safe while traveling through maintenance and construction work zones.

    • Do not speed in work zones. Obey the posted speed limits.
    • Stay Alert! Expect the unexpected.
    • Watch for workers. Drive with caution.
    • Don’t change lanes unnecessarily.
    • Avoid using mobile devices such as phones while driving in work zones.
    • Turn on headlights so that workers and other drivers can see you.
    • Be especially alert at night while driving in work zones.
    • Expect delays, especially during peak travel times.
    • Allow ample space between you and the car in front of you.
    • Anticipate lane shifts and merge when directed to do so.
    • Be patient!

    Download the COtrip App!

    The new free COtrip Planner mobile app was designed to meet the growing trend of information on mobile and tablet devices for the traveling public. The COtrip Planner app provides statewide, real-time traffic information, and works on mobile devices that operate on the iOS and Android platforms. Visit the Google Play Store (Android devices) or the Apple Store (iOS devices) to download!


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  • Youngstown State University’s redesigned website earns Silver Award in 13th Annual Education Digital Marketing Awards

    Youngstown State University’s newly redesigned website, ysu.edu, has been recognized with a Silver Award in the Institutional Website – Update/Refresh category of the 13th Annual Education Digital Marketing Awards.

    The Education Digital Marketing Awards celebrate innovative and effective digital communication efforts across the education sector. This year’s competition saw more than a thousand entries from colleges, universities and secondary schools across the country. Submissions were judged by a panel of education marketers, advertising creative directors, and industry professionals who evaluated creativity, design, functionality and strategic impact.

    YSU’s redesigned website — launched in April 2025 — was developed to offer a faster, cleaner, and more user-friendly experience. The updated ysu.edu features modern design elements, simplified navigation and enhanced functionality to help prospective students, current Penguins, faculty, staff, alumni and community members easily access the information they need. The site is fully responsive across devices and built with accessibility and engagement at its core.

    The redesign was shaped by campuswide feedback and crafted to better showcase YSU’s academic programs, campus life, and university news.

    YSU joins a distinguished list of institutions honored for digital innovation across 34 categories, including 229 that received Gold Awards, 139 that received Silver Awards and 79 that received Bronze.


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  • Council concern at over 1,000 Exertis job cuts after

    Council concern at over 1,000 Exertis job cuts after

    The Independent councillor said: “It is deeply concerning, especially right on top of Christmas for all the employees affected.

    “It’s a shock that this has happened and people deserve a full and transparent disclosure from the private equity owners and also those who sold the company in the first place.”

    In July, Aurelius said it would acquire Exertis UK, based in Burnley, and its Ireland division, based in Dublin.

    It said the technology distributor contributed about £2bn in revenue to its previous owner DCC plc in the previous year.

    In a statement announcing the deal, the private equity firm said: “Aurelius sees significant earnings growth potential for the business… enhanced by a recovery in market demand.”

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  • Percolation effect induced significant changes in the complex permittivity and permeability of silver-epoxy nano-composites

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  • MTA Weekender: December 12-15, 2025

    MTA Weekender: December 12-15, 2025

    Happy Friday and welcome to the second weekend in December! It looks like we’re headed for a wet weekend that could include some of the season’s first snow, so it’ll be a great time to take transit to some cozy, indoor holiday activities.

    A note for LIRR and Metro-North riders: alcohol will not be allowed on trains or in stations from 4 a.m. Saturday to noon Sunday.

    Here’s what else is happening this weekend (also viewable as a map):

    •   trains aren’t running between 168 St and 137 St-City College.
    • Queens-bound   and Euclid Av-bound   trains are running on the   from W 4 St-Wash Sq to Jay St-MetroTech.
    •   trains aren’t running between Court Sq and Bedford-Nostrand Avs.
    •   trains aren’t running between Hewes St and Broad St.
    •   trains aren’t running between Myrtle Av and Delancey St-Essex St.
    • Coney Island-bound   trains are running on the   from 36 St to Coney Island-Stillwell Av.
    • Bay Ridge-bound   trains are running on the   from Canal St to DeKalb Av.
    •   Franklin Av Shuttle isn’t running.

    For more details, keep on scrolling. We’ve also got travel alternatives for stations that will be closed or skipped.

    And don’t forget to sign up for the MTA Weekender newsletter sent every Friday. You’ll get these service changes directly in your inbox, with more than enough time to plan your weekend travel.

    Sign up for the Weekender!

    Major subway service changes

      trains, Manhattan

    From 9:45 p.m. Friday to 4 a.m. Monday,   trains aren’t running between 168 St and 137 St-City College in either direction and are running in two sections:

    • Between Van Cortlandt Park-242 St and 168 St, every 12 minutes during the day and evening.
    • Between 137 St-City College and South Ferry, every 8 minutes during the day and evening.

    This is because of structural maintenance.

    • For service to/from bypassed stations, take free shuttle buses, which are running between 168 St and 137 St-City College making all   stops. Or, use nearby    stations.
      • When exiting the subway at 168 St or 137 St-City College, get a GO Ticket from a station agent to re-enter.

        trains, Brooklyn, Manhattan, and Queens

    From 11:45 p.m. Friday to 5 a.m. Monday:

    • Queens-bound   and Euclid Av-bound   trains are running on the   from W 4 St-Wash Sq to Jay St-MetroTech.
    • Uptown    and   local trains aren’t stopping at Spring St and 23 St.
    • Uptown   and   local trains aren’t stopping at 50 St.
    • Downtown   trains are stopping at 50 St and 23 St all weekend.

    This is because of signal modernization and track maintenance.

    • For 50 St, take a downtown     or uptown   train.
    • For 42 St-Port Authority Bus Terminal, 34 St-Penn Station, 14 St, and W 4 St-Wash Sq, take downtown or uptown     trains.
    • For 23 St, take downtown     trains.
    • For Spring St, take a downtown   train or use nearby W 4 St-Wash Sq.
    • For Canal St, take a downtown   or uptown     train.
    • For Chambers St, take an uptown    train or the   at World Trade Center.
    • For Fulton St, take an uptown    train or use nearby World Trade Center  .
    • For High St, take a Manhattan-bound    train or use nearby York St  .

      trains, Manhattan and Queens

    From 11:45 p.m. Saturday to noon Sunday, World Trade Center-bound   trains are running on the   via Roosevelt Island from 21 St-Queensbridge to W 4 St-Wash Sq because of urgent repair work.

    • For service to/from Queens Plaza, use nearby Queensboro Plaza   .
    • For service to/from Court Sq-23 St, take the  .
    • For service to/from Lexington Av/53 St, use nearby Lexington Av/59 St  .
    • For service to/from 5 Av/53 St, use nearby 57 St or 47-50 Sts-Rockefeller Ctr.
    • For service to/from 7 Av, take the  .
    • For service to/from stations between 50 St and 14 St, take    trains.

      trains, Brooklyn and Queens

      trains aren’t running between Court Sq and Bedford-Nostrand Avs in either direction from 9:45 p.m. Friday to 5 a.m. Monday because of signal modernization.

    • For service between Court Sq and Bedford-Nostrand Avs, take free B98 shuttle buses, which are running between these stations making all   stops.
    • When exiting the subway at Court Sq, Lorimer St (Metropolitan Av), or Bedford-Nostrand Avs, get a GO Ticket from a station agent for re-entry.
    •   trains are running between Bedford-Nostrand Avs and Church Av.

       trains, Brooklyn and Manhattan

    From 11:45 p.m. Friday to 5 a.m. Monday:

    •   trains aren’t running between Hewes St and Broad St in either direction. 
      •  ​ trains are running between Jamaica Center-Parsons/Archer and Hewes St, every 12 minutes during the day and evening.
    •   trains aren’t running between Myrtle Av and Delancey St-Essex St in either direction.
      •  ​ trains are running between Middle Village-Metropolitan Av and Myrtle Av.

    This is because of track replacement.

    • For service between Myrtle Av and Hewes St, take the ​ .
    • For service between Hewes St and Delancey St-Essex St, take free B106 shuttle buses, which are running between these stations and stopping at Marcy Av.
      • When exiting the subway at Hewes St or Delancey St-Essex St, get a GO Ticket from a station agent to re-enter.
    • For service between Brooklyn and Manhattan, take     trains.
    • For service to Lower Manhattan, take     trains.

      trains, Brooklyn

    Coney Island-bound   trains are running on the   from 36 St to Coney Island-Stillwell Av from 3:45 a.m. Saturday to 10 p.m. Sunday because of track maintenance.

    • For service to/from bypassed stations, take a Manhattan-bound  .

       trains, Brooklyn

    From 11:45 p.m. Friday to 5 a.m. Monday:

    • Bay Ridge-bound   and Coney Island-bound   local trains are running on the   from Canal St to DeKalb Av.
      • At Canal St, Bay Ridge-bound   and Coney Island-bound   local trains are stopping at the   platform.
    • During late nights,   trains aren’t running between Whitehall St-South Ferry and Atlantic Av-Barclays Ctr in either direction, and are running nonstop between Atlantic Av-Barclays Ctr and 36 St in both directions.
      • Late-night  ​​ trains are running between Bay Ridge-95 St and 36 St and nonstop to/from Atlantic Av-Barclays Ctr.

    This is because of track replacement.

    • For service to/from bypassed stations in Manhattan, use nearby    or   stations.
    • For service to/from Court St and Jay St-MetroTech, use nearby Borough Hall    .
    • During late nights:
      • For service to/from DeKalb Av, take     trains.
      • For service between Union St and 25 St, take    trains.

      Franklin Av Shuttle, Brooklyn

    Franklin Av Shuttle trains aren’t running from 11:45 p.m. Friday to 5 a.m. Monday because of station maintenance.

    • Free shuttle buses are running between Franklin Av and Prospect Park, making all stops.
      • When exiting the subway at Franklin Av  , Franklin Av-Medgar Evers College    (Botanic Garden), or Prospect Park  , get a GO Ticket from a station agent to re-enter.

    Other subway service changes

        trains, Brooklyn

    Manhattan-bound    and   local trains are running nonstop from Franklin Av-Medgar Evers College to Atlantic Av-Barclays Ctr from 9:45 p.m. Friday to 5 a.m. Monday because of track replacement.

    • For service to/from bypassed stations, take a Flatbush Av-bound   or New Lots Av-bound   or   local train.
    •    trains are running every 12 minutes during the day and evening.

      trains, the Bronx

    Manhattan-bound   trains aren’t stopping at Mosholu Pkwy or Bedford Park Blvd-Lehman College from 6:45 a.m. Saturday to 5 p.m. Sunday because of track maintenance.

    • For service to/from these stations, take a Woodlawn-bound train.

      trains, Bronx

    Manhattan-bound   trains are running nonstop from Hunts Point Av to 3 Av-138 St from 9:45 p.m. Friday to 5 a.m. Monday because of structural maintenance.

    • For service to/from bypassed stations, take a Pelham Bay Park-bound train.
    • At 3 Av-138 St, all trains are boarding from the Pelham Bay Park-bound platform.

      trains, Queens

    Flushing-bound   trains are running express from 74 St-Broadway to Mets-Willets Point from 11:45 p.m. Friday to 3 a.m. Monday because of track replacement.

    • For service to/from bypassed stations, take a Manhattan-bound train.
    • At Junction Blvd, all trains are boarding from the Manhattan-bound platform.
    •   trains are running every 8 minutes during the day and evening.

      trains, the Bronx

    Norwood-bound   trains are running express from 145 St to Tremont Av from 11:45 p.m. Friday to 5 a.m. Monday because of track maintenance.

    • For service to/from bypassed stations, take a Coney Island-bound train.

      trains, Brooklyn

    Coney Island-bound   trains are running nonstop from 18 Av to Kings Hwy from 3:45 a.m. Saturday to 10 p.m. Sunday because of track maintenance.

    • For service to/from bypassed stations, take a Manhattan-bound train.
    • At 18 Av, all trains are boarding from the Manhattan-bound platform.

    Get updates

    These service changes are subject to change, so check the MTA homepage before heading out; it’s where you’ll find up-to-the-minute information on subway, bus, and rail service.

    Our apps—MTA and TrainTime—also provide real-time service information. You can also contact us in real time for help planning your trip.

    See how to contact us.

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  • Sobi to acquire Arthrosi Therapeutics, strengthening pipeline for the potential treatment of gout

    Sobi to acquire Arthrosi Therapeutics, strengthening pipeline for the potential treatment of gout

    –          Expands Sobi’s pipeline with a highly differentiated new Phase 3 asset in Gout

    –          Acquisition expected to be highly accretive to Sobi’s mid- to long-term growth and margin trajectory

     

    Sobi® (STO:SOBI) has entered into a definitive agreement to acquire Arthrosi Therapeutics, Inc. (Arthrosi), a private late-stage biotechnology company focused on developing a next-generation treatment for gout. The acquisition strengthens Sobi’s gout franchise by adding pozdeutinurad (AR882), an investigational next-generation, once-daily oral URAT1 inhibitor currently being evaluated in two fully recruited global Phase 3 clinical studies for the potential management of progressive and tophaceous gout and expected to read out in 2026. Pozdeutinurad complements Sobi’s pipeline by adding a potentially best-in-class URAT1 inhibitor for patients sub-optimally treated with first-line therapies. Today’s announcement reflects Sobi’s commitment to advancing treatment options for people living with gout.

     

    “The acquisition of Arthrosi allows us to expand our gout pipeline with a highly differentiated new asset”, said Guido Oelkers, President and CEO of Sobi. “Pozdeutinurad has the potential to become the therapy of choice for patients who have progressive gout with persistent and unresolved symptoms despite first-line therapy. The product has the potential to materially accelerate our growth until the mid 2030s, and beyond. We welcome all members of the talented Arthrosi team and are looking forward to working closely together to be able to offer this therapy to patients as soon as possible.”

     

    “We are thrilled to join forces with Sobi and look forward to working together to ensure a seamless transition as they advance pozdeutinurad towards pivotal data and potential regulatory filings. We believe that Sobi’s global expertise in commercialisation will accelerate our shared mission to deliver pozdeutinurad’s potentially transformative benefits for individuals living with gout”, stated Litain Yeh, Ph.D., Founder and CEO of Arthrosi Therapeutics.

     

    Transaction details

    Under the terms of the agreement, Sobi will pay USD 950 million (approximately SEK 9.1 billion) upfront in cash to acquire Arthrosi, together with up to USD 550 m (approximately SEK 5.3 billion) in cash in clinical, regulatory and sales milestones.

     

    The transaction is subject to the satisfaction of customary closing conditions and is expected to close in H1 2026.

     

    Sobi plans to fund the upfront payment mainly through debt in the form of existing credit facilities and a new credit facility provided by Handelsbanken and Danske Bank.

     

    The acquisition is expected to be highly accretive to Sobi’s mid- to long-term growth and margin trajectory.

     

    Barclays Bank PLC is acting as Sobi’s financial advisor and McDermott, Will & Schulte is acting as legal advisor to Sobi on this transaction.

    About Pozdeutinurad

    Pozdeutinurad (AR882) is an investigational URAT1 inhibitor being developed for the treatment of progressive and tophaceous gout and has completed Phase 2 studies that demonstrated compelling efficacy with a sustained reduction of serum uric acid, dissolution of tophi and a well-tolerated safety profile.  It is currently being evaluated in two Phase 3 studies, REDUCE 1 and REDUCE 2, two twelve-month, randomized, double-blind, placebo-controlled studies to assess pozdeutinurad’s ability to reduce sUA in patients with progressive and tophaceous gout. Both Phase 3 studies are now fully enrolled, and the pivotal data is expected in 2026.

     

    About Arthrosi

    Arthrosi Therapeutics, Inc., headquartered in San Diego, CA, is focused on developing pozdeutinurad, a potentially best-in-class, highly potent and selective next generation URAT1 inhibitor to reduce serum urate levels, flares and tophi in patients with progressive gout. The rights to pozdeutinurad in Greater China are held by ApicHope.

     

    Invitation to conference call

    Investors, analysts and media are invited to participate in a conference call which will include a presentation and a Q&A session on the 15th December at 08:00 CET.  The presentation can be followed live here or afterwards on sobi.com. The slides will be made available on sobi.com.

    To participate in the conference call, please use the following dial-in details:

     

    Sweden: +46 8 5051 0031

    United Kingdom: +44 207 107 06 13

    United States: +1 631 570 56 13

    For other countries, please find the details here.

     

     

    About Gout

    Gout is the most common form of inflammatory arthritis. Gout is caused by high levels of uric acid in the body that accumulate around the joints and other tissues and can result in flares that cause intense pain. When gout is left untreated, it can become a progressive disease with serious consequences. Over time, frequent flares and persistent uric acid buildup can lead to chronic joint damage, reduced mobility, and the formation of tophi (hard deposits under the skin). While many patients with chronic gout are treated in first line with urate lowering therapy some are sub-optimally treated or do not respond to first line therapies and the disease progresses. In later lines, uncontrolled gout is associated with a higher risk of comorbidities such as kidney disease and cardiovascular complications, making early diagnosis and effective management critical. Despite available treatments, many patients struggle to achieve target uric acid levels, underscoring the need for innovative therapies to prevent long-term disability and improve quality of life.

     

     

    Sobi®

    Sobi is a global biopharma company unlocking the potential of breakthrough innovations, transforming everyday life for people living with rare diseases. Sobi has approximately 1,900 employees across Europe, North America, the Middle East, Asia and Australia. In 2024, revenue amounted to SEK 26 billion. Sobi’s share (STO:SOBI) is listed on Nasdaq Stockholm. More about Sobi at sobi.com and LinkedIn.

     

     

    Contacts

    For details on how to contact the Sobi Investor Relations Team, please click here. For Sobi Media contacts, click here.

     

    This information is information that Sobi is obliged to make public pursuant to the EU Market Abuse Regulation. The information was submitted for publication, through the agency of the contact person set out below, at 17:00 CET on 13 December 2025.

     

    Gerard Tobin

    Head of Investor Relations

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    Alamy Islands in the Caribbean have seen record numbers of Canadians this year (Credit: Alamy)Alamy
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    Meanwhile, US destinations that typically rely on Canadian tourism are feeling the impact. Between January and July, 30% fewer Canadians crossed the border into Vermont compared to the same period in 2024. Las Vegas has seen an 18% year-to-date decline, and places like Ft Lauderdale, Upstate New York and many other regions are experiencing similar downturns.

    An increase in flight connectivity to Europe and the Caribbean is making it easier for Canadians to bypass the US. “From Canada to Berlin, Ponta Delgada, Nantes and Brussels, we are strategically increasing new non-stop routes across Europe to bring convenient access to key destinations, while strengthening economic ties and supporting tourism,” Air Canada executive vice president and chief commercial officer Mark Galardo said in a statement.

    From 4-20 December, the airline is also launching 13 new routes to the Caribbean, Central America and South America – a move that is likely aimed at Canadian “snowbirds” who previously relied on US states like Florida or California for winter sun.

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