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  • Journal of Medical Internet Research

    Journal of Medical Internet Research

    With the widespread adoption of low-dose computed tomography screening, the detection rate of pulmonary nodules (PNs) continues to increase []. Longitudinal imaging surveillance and comparison with prior examinations are foundational to PN management and are consistently emphasized in major guidelines [,]. In routine practice, patients often receive care across multiple institutions and seek additional opinions; when prior images are not retrievable promptly and reliably, repeat scanning and delays in care become likely. Evidence indicates that cross-regional or interinstitutional health information exchange (HIE) is associated with fewer duplicate imaging examinations and lower related costs [,].

    In recent years, internet hospitals that commonly refer to hospital-affiliated online clinical services that extend routine care pathways through digital platforms, rather than stand-alone telemedicine encounters, have become an important complement to in-person clinics for remote consultation and follow-up. Real-world data suggest that their use is associated with fewer visits and lower costs [,], yet such encounters rely even more heavily on HIE. Enabling cross-institutional and cross-channel reuse of imaging requires cloud-based tools built on the Digital Imaging and Communications in Medicine (DICOM) or DICOMweb standards, which are collectively referred to as cloud-based medical imaging (CMI), and they support interoperable data exchange and network retrieval []. Recent implementations show that DICOMweb-based workflows can deliver web-based image viewing, improving visit efficiency. Recent surveys of web-based DICOM viewers suggest that DICOMweb support is increasingly common, but implementation depth and performance vary across products and settings []. Meanwhile, direct patient access to images is increasingly common. Although this can enhance knowledge and engagement, the absence of patient-facing explanations may trigger or amplify “scanxiety” []. Accordingly, information availability and interpretability represent distinct challenges. Recent studies showed that patient engagement with radiology reports and images is heterogeneous with respect to uptake, timing, and depth and differs across patients []. When patients review radiology results, they often encounter clinician-oriented terminology with limited general explanation, which may hinder comprehension and contribute to concern even when results are available in a timely manner [,]. A recent systematic review reported that patient-oriented reporting features, including plain-language summaries, glossaries, and visual aids, are associated with improved comprehension and satisfaction and may reduce avoidable anxiety [].

    In this imaging-dependent clinical context, timely retrieval and cross-channel reuse of imaging studies are prerequisites for effective longitudinal management. However, empirical evidence specific to populations with PNs remains sparse regarding CMI availability versus actual use, its associations with health care utilization and financial burden, user experience, and interoperability barriers. While digital image accessibility has been studied in general contexts, this research represents the first mixed methods study to focus on the unique PN care landscape in China. In this context, effective management is heavily dependent on long-term, high-frequency longitudinal imaging comparisons, making current limitations, such as brief data retention and system fragmentation, particularly impactful. Furthermore, unlike the unified patient portals common in other regions, the Chinese mobile health ecosystem is characterized by fragmented, QR code–based access, which presents distinct usability challenges. Beyond describing accessibility, this study provides a robust analysis of the correlations between actual CMI use and health care utilization, financial burden, and patient cognition, offering a holistic perspective on the “possession-to-use gap” that has not been previously characterized. This study aimed to characterize, within PN care, the landscape of CMI availability and use; quantify its associations with health care utilization and costs; assess relationships with disease perceptions; and, through qualitative inquiry, identify key usability and interoperability barriers to inform optimization and scale-up.

    Study Design and Participants

    We used an explanatory sequential mixed methods design. Survey findings informed the interview guide and purposive sampling, and integration was conducted through a prespecified comparison framework and meta-inferences based on convergence, complementarity, and discrepancies. Integrated findings are reported using narrative weaving that links quantitative results with qualitative themes and illustrative quotes. The reporting of the quantitative component follows the STROBE (Strengthening the Reporting of Observational Studies in Epidemiology) guideline, and the qualitative component was designed, conducted, and reported with reference to the COREQ (Consolidated Criteria for Reporting Qualitative Research). From October 2022 to May 2024, consecutive patients with PNs were recruited via a thoracic surgery e-consultation clinic on a national telemedicine platform []. In total, 701 participants completed the structured survey. Eligibility criteria were newly identified or undersurveillance PNs, age ≥18 years, and ability to complete the questionnaire. We excluded individuals who had already undergone resection or had a definitive pathological diagnosis.

    To complement and contextualize the quantitative findings, we conducted semistructured interviews with a purposive, maximum-variation sample of 10 patients and 10 physicians. Patient participants varied by age (26‐73 y), sex, and educational level. Physician participants were thoracic surgeons spanning junior, mid-career, and senior ranks.

    Ethical Considerations

    This study was approved by the Research Ethics Committee of Guangdong Provincial People’s Hospital (approval number: 2025-KY-122‐01). All participants provided written informed consent under institutional ethics approval. All questionnaire and interview data were deidentified before analysis, and access was restricted to the research team. The research team collected questionnaire responses and qualitative interview materials; we did not collect, download, store, or process participants’ DICOM files or other raw radiology image files as part of the study procedures. Participants received no compensation for participation.

    Measures and Variables

    In China, CMI is commonly obtained or shared as DICOM files viewable in a browser, QR codes appended to radiology reports, or links on hospital websites. For QR code or web link access, the code or link typically directs patients to an institution-hosted or vendor-hosted web viewer. Depending on the implementation, the viewer may be DICOM-based (including zero-footprint viewers) or may rely on proprietary web formats; therefore, QR or link access should not be assumed to be DICOMweb-compliant. Some patients receive only a textual report and/or film, with no CMI access. We defined use of CMI as the self-reported ability to view radiological images on a mobile device. This measure does not differentiate between passive access and more active or intensive use, nor does it quantify frequency or depth of use. Sociodemographic and clinical variables included age, sex, education (primary, middle school, high school, junior college, undergraduate, and graduate), and surveillance status. Care-seeking and cost measures comprised the number of hospitals used (internet and offline), the total number of physicians consulted, and annual out-of-pocket expenditures (care-related fees, transportation, lodging). Self-efficacy and disease perceptions included perceived disease severity, level of disease awareness, and change in anxiety level.

    Qualitative Interviews: Design, Data Collection, and Management

    We developed separate interview guides for patients and physicians (). The guides covered CMI awareness and use, preferences of CMI format, perceived clinical benefits and limitations, workflow usability and pain points, psychological responses, and priorities for system improvement. Trained qualitative researchers conducted in-person interviews (20‐40 min). With permission, sessions were audio-recorded and accompanied by field notes. Recordings were transcribed verbatim, deidentified, and stored on password-protected devices. Texts were managed and queried in NVivo (version 11; QSR International Pty Ltd). Bilingual researchers translated quotations for manuscript presentation with dual review; discrepancies were resolved by revisiting the Chinese original. Additionally, interviews and analysis proceeded iteratively. During concurrent coding, we tracked the emergence of new codes and concluded interviewing when successive interviews no longer generated new major themes and the coding framework had stabilized.

    Data Analysis

    Quantitative Analysis

    Continuous variables were summarized using medians and interquartile ranges, whereas categorical variables were summarized as frequencies and percentages. The primary outcome was the use of CMI, defined as whether participants accessed and viewed their imaging data through CMI. Group comparisons were performed using chi-square or Mann-Whitney U tests. To quantify associations with CMI use, odds ratios with 95% CIs were estimated using univariable and multivariable logistic regression. To minimize confounding, propensity score matching was conducted with CMI use as the dependent variable. Prespecified covariates included age, sex, education, and surveillance duration. Nearest-neighbor 1:1 matching was applied using a caliper width of 0.02 times the SD of the logit of the propensity score. Covariate balance was assessed using standardized mean differences (<0.10). In the matched sample, health care utilization, financial burden, and disease perceptions were compared between CMI users and nonusers. Analyses were performed using SPSS Statistics (version 26.0; IBM Corp), and visualizations were created in GraphPad Prism (version 8.0).

    Qualitative Analysis and Integration

    Two researchers independently reviewed all transcripts, wrote reflexive memos, and conducted line-by-line open coding using in vivo codes where appropriate. After independent coding, the team discussed and resolved discrepancies; merged overlapping codes; refined code boundaries; and compiled a shared, version-controlled codebook. A constant comparative approach was used to group semantically related codes into categories within each participant group and to compare categories across groups using a patient-versus-physician matrix, identifying areas of convergence and divergence. Potentially disconfirming cases were examined to test the robustness of themes, which were iteratively refined based on clarity, coherence, and distinctiveness. Approximately 20% of the transcripts were double-coded for quality assurance, with disagreements resolved through discussion. An auditable analytic trail and reflexive notes were maintained throughout. Member checking was not undertaken. However, integration was performed through using the quantitative results to inform interview focus and an explicit joint display and narrative weaving to connect quantitative patterns with qualitative explanations and identify areas of convergence and discrepancy.

    CMI Possession and Use

    Overview

    Among 701 patients with PNs, 87.2% (n=611) had obtained CMI. Of these, 47.1% (n=330) acquired it by requesting from hospitals, while 40.1% (n=281) received it proactively from hospitals; 12.8% (n=90) had only reports or films without CMI. The main modalities were QR code or web link (n=352, 50.3%) and DICOM files (n=259, 36.9%). Overall, 57.6% (n=404) were CMI users, and 42.4% (n=297) were nonusers ().

    Table 1. Possession and application of CMI among patients with PNs.
    Possession categories, application of CMI, and variables Patients, n (%)
    Possession of CMI
    No, I only got radiological report and/or film 90 (12.8)
    Radiological reports and films 79 (11.3)
    Radiological reports 11 (1.6)
    Yes, I got it by applying to the hospital 330 (47.1)
    DICOM files 259 (36.9)
    Yes, hospitals took initiative to provide it 281 (40.1)
    QR code or web links 352 (50.3)
    Application of CMI
    Users of CMI 404 (57.6)
    Nonusers of CMI 297 (42.4)

    aCMI: cloud medical images.

    bPN: pulmonary nodule.

    cDICOM: Digital Imaging and Communications in Medicine.

    Baseline Differences and Independent Correlates of CMI Use

    In the unmatched sample (), users were younger than nonusers (median 46, IQR 38‐55 y vs median 48, IQR 39‐57 y; P=.001), and distributions differed for education (overall P=.004) and prior internet-clinic experience (overall P=.03). Sex (P=.60) and time since nodule detection (P=.09) did not differ. In multivariable logistic regression (), age was independently and inversely associated with CMI use (odds ratios 0.985, 95% CI 0.972‐0.999; P=.04), while education was not significant after adjustment (P=.21).

    Table 2. Comparison of baseline characteristics between users and nonusers of CMI.
    Variable Overall (N=701) Users (n=404, 57.6%) Nonusers (n=297, 42.4%) P value
    Age (y), median (IQR) 48 (39-57) 46 (38-55) 48 (39-57) .001
    Sex, n (%) .60
     Female 435 (62.1) 254 (62.9) 184 (60.9)
     Male 266 (37.9) 151 (37.1) 105 (39.1)
    Education attainment, n (%) .004
     Primary school 24 (3.4) 8 (2.0) 16 (5.4)
     Junior high school 68 (9.7) 41 (10.1) 27 (9.1)
     Senior high school 88 (12.6) 43 (10.6) 45 (15.2)
     Junior college 150 (21.4) 79 (19.6) 71 (23.9)
     Undergraduate 291 (41.5) 181 (44.8) 110 (37.0)
     Graduate 80 (11.4) 52 (12.9) 28 (9.4)
    Online consultation, n (%) .03
     Never 207 (29.5) 99 (24.5) 108 (36.4)
     Ever but need assistance 288 (41.1) 184 (45.5) 104 (35.0)
     Ever and not need assistance 266 (37.9) 121 (30.0) 85 (28.6)
    Time to the first detection of PNs (mo), median (IQR) 12 (3-32) 14 (4-32) 12 (2-33) .09

    aCMI: cloud medical images.

    bPNs: pulmonary nodules.

    Table 3. Binomial logistic regression analysis for influencing factors of CMI application in patients with PNs.
    Variable Univariate analyses Multivariate analysis
    OR (95% CI) P value OR (95% CI) P value
    Age (y) 0.979 (0.967‐0.991) .001 0.985 (0.972‐0.999) .04
    Time (mo) 0.998 (0.993‐1.004) .58
    Sex (reference: female) .60
     Male 0.921 (0.677‐1.254)
    Education attainment (reference: primary school) .02 .21
     Junior high school 3.037 (1.142‐8.075) .03 2.655 (0.989‐7.123) .05
     Senior high school 1.911 (0.742‐4.922) .18 1.651 (0.634‐4.300) .30
     Junior college 2.225 (0.898‐5.513) .08 1.833 (0.726‐4.626) .20
     Undergraduate 3.291 (1.363‐7.943) .008 2.449 (0.973‐6.162) .06
     Graduate 3.714 (1.415‐9.750) .008 2.583. (0.929‐7.178) .07

    aCMI: cloud-based medical images.

    bPN: pulmonary nodule.

    cNot applicable.

    Health Care Utilization, Costs, and Perceptions After Matching

    After 1:1 propensity score matching, baseline balance was achieved, the main directional differences observed prematching generally persisted (Table S1 in ) and the covariate balance before and after propensity score matching persisted in . In the matched cohort, as shown in , the distribution for number of internet hospitals (median 1, IQR 0‐1 vs median 1, IQR 0‐1; P=.01) used differed significantly between users and nonusers, whereas, as shown in , the number of offline hospitals (median 2, IQR 1‐2 vs median 1, IQR 1‐2; P=.19) did not differ. The number of physicians consulted (median 3, IQR 1‐3 vs median 2, IQR 1‐3; P=.02) is also displayed in . CMI users were significantly more likely to spend 0‐2500 Chinese Yuan (CNY; US $1=6.87 CNY) on treatment and diagnostic costs (229/291, 78.7% vs 201/291, 69.1%; P=.004) and on travel and accommodation expenses (249/291, 85.6% vs 229/291, 78.7%; P=.03), suggesting they incurred lower expenses compared to nonusers. As presented in , regarding disease perceptions, users reported higher levels of disease awareness (overall P=.009), whereas perceived disease severity (overall P=.97) and anxiety change (overall P=.81) did not differ ().

    Figure 1. Health care utilization, costs, and perceptions after 1:1 propensity score matching. Note that 100% stacked bar charts compare cloud-based medical imaging (CMI) Users and Nonusers on 8 outcomes: (A) number of internet hospitals, (B) number of offline hospitals, (C) number of consulting physicians, (D) treatment and diagnostic costs, (E) travel and accommodation expenses, (F) perceived disease severity, (G) level of disease awareness, and (H) change in anxiety level. Bars show the percentage distribution of categories within each group (cost bands: Chinese Yuan [CNY] 0‐2500, 2500‐5000, 5000‐7500, and 7500‐10,000; ≥10,000; other category labels as shown in panel legends; all costs reported in CNY were converted to US dollars using an exchange rate of US $1=6.87 CNY). P values above panels compare distributions between the groups using 2-sided chi-square tests. Significant differences were observed for internet hospitals (P=.01), consulting physicians (P=.02), treatment or diagnostic costs (P=.004), travel or accommodation expenses (P=.03), and disease awareness (P=.009); no differences were found for offline hospitals (P=.19), perceived severity (P=.97), or change in anxiety (P=.81). Baseline balance after matching is shown in Table S1 in .

    Stratification by Access Modality (DICOM vs QR Code or Web Link) Among Users

    Among CMI users, in , the DICOM group differed from the QR or link group in distributions of the number of offline hospitals (median 2, IQR 1‐2 vs median 2, IQR 1‐2; P=.04) and the number of physicians consulted (median 3, IQR 2‐4 vs median 3, IQR 1‐3; P=.02) as depicted in , whereas as shown in , the number of internet hospitals (median 1, IQR 0‐2 vs median 1, IQR 0‐2; P=.99) did not differ. The DICOM group had no difference in treatment and diagnostic costs (95/132, 72.0% vs 209/261, 80.1%; P=.09) and travel and accommodation expenses (108/132, 82.6% vs 223/261, 85.4%; P=.52) with the majority spending 0‐2500 CNY, but higher disease knowledge (overall P=.004) as presented in . The groups did not differ in perceived severity (overall P=.17) or anxiety change (overall P=.19; ).

    Figure 2. Outcomes among cloud-based medical imaging (CMI) users stratified by access modality (Digital Imaging and Communications in Medicine [DICOM] vs QR code or web link). Among CMI users only, 100% stacked bar charts compare those accessing the service via DICOM versus QR code or web link across the same 8 outcomes: (A) number of internet hospitals, (B) number of offline hospitals, (C) number of consulting physicians, (D) treatment and diagnostic costs, (E) travel and accommodation expenses, (F) perceived disease severity, (G) level of disease awareness, and (H) change in anxiety level. Bars display percentage distributions for each category (cost bands identical to ). P values above panels indicate 2-sided chi-square tests comparing modalities. Significant differences were seen for offline hospitals (P=.04), consulting physicians (P=.02), and disease awareness (P=.004). No significant differences were observed for internet hospitals (P=.99), treatment or diagnostic costs (P=.09), travel or accommodation expenses (P=.52), perceived severity (P=.17), or change in anxiety (P=.19).

    Integrated Findings Across Quantitative and Qualitative Strands

    Across both strands, we observed a consistent possession-to-use gap: most participants obtained CMI, but only a subset reported using it. The interview data indicate that this gap reflects not only access but also day-to-day usability barriers and system limitations, including burdensome authentication steps, inconsistent workflows across hospitals, and short retention periods that make access links unreliable. After matching, the observed patterns in health care use and self-reported costs aligned with the convenience and efficiency benefits described in interviews, while psychological responses to viewing images varied in direction. A joint display linking key quantitative results with qualitative themes and illustrative quotes is provided in Table S2 in .

    Qualitative Themes

    Overview

    We identified five overarching themes: (1) convenience and clinical value, (2) heterogeneous user experience and system usability, (3) limited retention time and poor interoperability, (4) psychological effects and communication, and (5) improvement priorities and governance. Representative quotes and themes are provided below () and in .

    Table 4. Themes and representative quotes.
    Theme Representative quotes
    Care convenience and clinical value
    • “I used to carry film to every visit; now showing the images on my phone is enough.” (Patient)
    • [“When I follow up at another hospital, clinicians can view my prior images, saving many unnecessary steps.” (Patient)
    • “Cloud-based imaging turns pulmonary nodule surveillance from discontinuous checkpoints into a continuous trajectory.” (Physician)
    Divergent user experience and system usability
    • “Different hospitals require different accounts; I often can’t remember them.” (Patient)
    • “When the connection is poor, the whole process fails.” (Patient)
    • “There are too many steps to access the images; during busy clinics this disrupts workflow.” (Physician)
    • “Window width and window level are difficult to adjust, which affects assessment of key details.” (Physician)
    Limited retention and poor interoperability
    • “QR codes expire after a while, so at the next visit I have to start over.” (Patient)
    • “Restrictions on the number of downloads are inconvenient.” (Patient)
    • “Lack of interoperability creates information silos, making repeat imaging hard to avoid.” (Physician)
    • “Without unified standards, retrieving outside images feels like assembling a jigsaw.” (Physician)
    Psychological effects and communication
    • “Seeing the imaging changes makes me feel more in control.” (Patient)
    • “There is too much medical terminology I don’t understand, which makes me more anxious.” (Patient)
    • “We need to ‘translate’ images into conclusions and recommendations that patients can understand.” (Physician)
    Improvement priorities and governance
    • “Ideally, a single platform would be usable nationwide.” (Patient)
    • “Prioritize speed, clarity, stability, and privacy first; artificial intelligence (AI) features can come later.” (Physician)
    • “It would be ideal to place history, reports, and images together in one ‘case folder.’” (Physician)
    Theme 1: Convenience and Clinical Value

    Patients and physicians agreed that CMI reduces patient burden and improves clinical efficiency. Patients emphasized not needing to carry films and smoother cross-institution visits; physicians highlighted longitudinal comparison of nodules, fewer unnecessary repeat scans, shorter visit times, and improved access for distant patients.

    Patient: I no longer carry a stack of films—showing the images on my phone is enough
    Patient: When I switch hospitals, prior images can be pulled up, and it’s easier for the doctor to decide on follow-up.
    Physician: Having previous images side-by-side makes surveillance decisions more coherent and reduces repeat CTs.
    Physician: For out-of-town patients, remote consults with shared images are much more efficient.

    Theme 2: Heterogeneous User Experience and Usability

    Experience diverged: younger or more digitally literate patients navigated smoothly, whereas older patients struggled with login, verification, account linking, scanning steps, bandwidth, and device limitations. Physicians cited slow loading, complex workflows, suboptimal image quality, windowing controls, and heterogeneity across hospital platforms.

    Patient: Some QR codes open directly; others require registration and verification—too many steps.
    Patient: If the network is poor, I just give up.
    Physician: When the clinic network slows, image loading disrupts the flow of consultation.
    Physician: Different platforms work differently; the learning burden prevents a stable routine.

    Theme 3: Limited Retention and Interoperability Gaps

    Short retention periods, expired links or QR codes, download limits, and weak cross-institution interoperability were common pain points. Patients could not retrieve older studies for long-term surveillance; physicians faced siloed platforms and resorted to repeat testing.

    Patient: Links stop working after a year or two, making longitudinal comparison difficult.
    Patient: Limits on how many times the link can be opened are especially inconvenient.
    Physician: Platform fragmentation leads to information silos and, inevitably, duplicate imaging.
    Physician: Without unified interfaces, retrieving outside images is inefficient.

    Theme 4: Psychological Effects and Communication

    CMI had bidirectional psychological effects: some patients felt reassured by ready access; others became anxious due to misinterpretation. Physicians noted that clear explanation is essential to avoid overinterpretation and undue worry.

    Patient: Seeing my images makes me feel more in control.
    Patient: The terminology is confusing; the more I look, the more anxious I feel.
    Physician: Without explanations, patients may overread images and worry unnecessarily.

    Theme 5: Improvement Priorities and Governance

    Patients and physicians broadly agreed on priorities but with different emphases. Patients wanted longer retention, removal of access limits, simpler flows, and cross-institution sharing. Physicians emphasized speed and clarity, unified standards or platforms, integration of history and reports, clear privacy and accountability, and gradual introduction of artificial intelligence–assisted localization and comparison.

    Patient: Ideally, images would be stored long-term without repeated registration.
    Physician: We need unified data standards and interfaces, integrating imaging, reports, and history into one workflow.
    Physician: Baseline requirements are clarity, loading performance, stability, and privacy; these should be solved first.

    Principal Findings

    This mixed methods study shows that most hospitals can provide CMI in varied formats, yet a substantial possession-to-use gap persists. Compared with nonusers, CMI users engaged more with internet hospitals and physicians, reported lower care-related and travel or lodging costs, and self-reported higher disease knowledge. Qualitative findings pinpointed system usability, retention, timeliness, and interoperability as principal limitations. Overall, our results align with recent evidence on the accessibility and cost advantages of internet hospitals [] and the association between interoperability and reduced duplicate imaging [], offering practical directions for improving workflows.

    Older age was independently associated with lower CMI use, whereas education was not significant after adjustment. This aligns with reviews showing that older adults face barriers with digital health tools—account/identity verification complexity, dense information, jargon, input burden, and screen design can all hinder adoption and sustained use [,]. Our interviews echoed concrete obstacles, such as multiplatform authentication, link expiry, and loading instability. For this population, the most effective improvements are those that reduce usability barriers rather than simply expanding access. Examples include single sign-on with unified entry points, clinic-side preloading combined with direct viewer access, caregiver proxy accounts, and concise instructional micro-guides, all of which have been shown to enhance eHealth participation among older adults [-].

    Quantitatively, users interacted with more internet hospitals and physicians, while the number of offline hospitals did not change, suggesting that CMI may improve the efficiency and quality of care pathways rather than simply reducing in-person visits. Lower patient-reported costs for users are consistent with the reduced service frequency and improved accessibility observed with internet hospitals []. From a continuity-of-information perspective, integrated longitudinal viewers and HIE platforms reduce repeat imaging and patient burden [], aligning with our cost-direction findings. Although users reported greater disease knowledge, perceived severity and anxiety did not differ, echoing prior work that immediate online access can increase knowledge but may sustain “scanxiety” in the absence of explanatory support []. Qualitative findings further contextualize these patterns by illustrating how CMI facilitates more efficient remote consultations and transforms surveillance into a continuous trajectory. These insights help interpret the observed cost reductions as a direct result of fewer unnecessary repeat scans and improved clinical efficiency during cross-institutional visits. The qualitative theme of limited retention and poor interoperability may also help explain the possession-to-use gap observed in our quantitative results, that even when patients have access to CMI, short retention periods and cross-institution barriers can reduce the practical usefulness of CMI and discourage actual use. Finally, the qualitative theme of bidirectional psychological effects explains why increased knowledge may not lower anxiety, as patients reported feeling more in control while simultaneously feeling confused by complex terminology in the absence of professional translation.

    Stratification by access modality indicated advantages for DICOM over QR or link access in engagement and knowledge—plausibly due to DICOM’s interactivity, longer-term retention, and standardization, which facilitate time-series comparison and remote consultation. Technically, mature DICOMweb workflows support browser-based import and zero-footprint viewing suited to both lightweight patient access and professional clinical review []. At a systems level, better regional informatics and interoperability correlate with improved health service performance [].

    Our interviews highlighted short retention periods, inconsistent rules, and fragile links and QR codes as major obstacles, which undermine in-clinic retrieval. Consistent with research on patient portals, stable and renewable access points with clear audit trails and proactive expiry reminders are foundational for practical use, especially among older adults []. Clinically, immediate simultaneous access to prior images during the visit is critical. Rather than adding new entry points, default patient-centered retrieval organized by patient, chronological timeline, and imaging series, together with online comparison, should be standard capabilities. Workflows based on DICOMweb and zero footprint viewers already enable standardized retrieval and reliable online comparison without local installation [], and access to prior images reliably reduces repeat testing and delays [].

    Our findings suggest that interoperability and durable access in CMI are not only technical issues but also governance issues that require consistent rules for minimum retention periods, renewable access, audit trails, and accountability across institutions []. China’s national health informatization agenda has emphasized standardization and interoperability maturity certification, which provides an actionable foundation to operationalize imaging-specific retention and exchange requirements at scale []. Building on recent analyses that identify standards, interoperability, legislation, and compliance as the core foundations of China’s digital health governance for the Healthy China 2030 initiative, the clinical management pathway for pulmonary nodule surveillance can be strengthened by aligning platform requirements with these governance elements [,]. Finally, equity-oriented implementation is needed to ensure that national digital health strategies translate into broadly accessible longitudinal imaging services rather than widening existing digital divides [].

    Limitations

    This cross-sectional design precludes causal inference. Visit counts, costs, and disease perceptions were self-reported and thus subject to recall and reporting bias. Recruitment through online and hospital settings may have overrepresented digitally literate individuals, limiting external validity. Consequently, the 57.6% usage rate likely represents an upper bound for this population, and the lack of regional stratification may mask even steeper barriers in underconnected or rural areas. Therefore, our findings are most applicable to digitally connected patients with PNs who engage in cross-institutional care and remote consultation and should be extrapolated cautiously to offline-only pathways and underserved settings. Although propensity score matching mitigated confounding, residual confounding cannot be excluded. The measure of CMI use does not distinguish passive access from more active use, and we did not capture frequency or depth of use. The qualitative sample was modest and did not include participant checking. Future studies could improve construct validity by incorporating intensity indicators ideally complemented by objective usage logs where feasible. Future multisite sampling, longitudinal, or quasi-experimental studies are also warranted to validate these findings and assess long-term adoption trajectories.

    Conclusions

    In PN management, CMI is widely available yet remains underused. Actual use was associated with greater engagement in online care, lower related costs, and higher self-reported disease knowledge. Qualitative findings identified 3 actionable constraints—usability thresholds, unstable data retention, and inconsistent clinical viewing functions. Addressing these limitations requires ensuring renewable, auditable, and stable access, together with default support for longitudinal, in-browser comparison.

    We acknowledge that ChatGPT (OpenAI) was used to assist in language editing and improving the clarity of the manuscript.

    This study was supported by the Noncommunicable Chronic Diseases-National Science and Technology Major Project (2024ZD0529400 & 2024ZD0529401) and National Key R&D Program of China (2022YFE0133100).

    The datasets generated or analyzed during this study are not publicly available due to privacy restrictions and institutional policies on patient data sharing but are available from the corresponding author on reasonable request.

    All authors had full access to all of the data (including statistical reports and tables) in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.

    Author GL is the co-corresponding author (phone: 86 18680494527; email: 152537065@qq.com)

    None declared.

    Edited by Alicia Stone; submitted 29.Oct.2025; peer-reviewed by Olajide Akinpeloye, Taofeek Jimoh; final revised version received 25.Feb.2026; accepted 25.Feb.2026; published 30.Mar.2026.

    © Ziguo Chen, Junhan Wu, Yunying Chen, Weitao Zhuang, Jiaxuan Huang, Weifeng Zhong, Zijie Li, Shuhuan Xie, Chaofan Liu, Guojie Lu, Guibin Qiao. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 30.Mar.2026.

    This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research (ISSN 1438-8871), is properly cited. The complete bibliographic information, a link to the original publication on https://www.jmir.org/, as well as this copyright and license information must be included.

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  • Advancing the next era of energy security – Chevron

    1. Advancing the next era of energy security  Chevron
    2. Leaders and Experts from Amazon Web Services, Google, Microsoft, NVIDIA, Meta, Dell, Applied Materials and AMD Headline Technology and Innovation Programming at CERAWeek by S&P Global, March 23-27 in Houston  PR Newswire
    3. CERAWeek energy conference 2026 in Houston  Reuters Connect
    4. Energy is at the center of everything now. Welcome to the most intense CERA Week ever. | Opinion  Houston Chronicle
    5. The Hamm Institute for American Energy hosts critical discussions during CERAWeek 2026  news.okstate.edu

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  • FDA Grants Priority Review to Lirafugratinib for FGFR2+ Pretreated Cholangiocarcinoma – OncLive

    1. FDA Grants Priority Review to Lirafugratinib for FGFR2+ Pretreated Cholangiocarcinoma  OncLive
    2. HLB’s experimental drug gains FDA fast-track review status  The Korea Times
    3. Elevar Therapeutics Announces FDA Acceptance for Review of  GlobeNewswire
    4. HLB Receives FDA Priority Review For Lirafugratinib  Let’s Data Science

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  • Stock market today: Live updates

    Stock market today: Live updates

    A trader works on the floor of the New York Stock Exchange during morning trading on March 25, 2026 in New York City.

    Michael M. Santiago | Getty Images

    The Dow Jones Industrial Average traded higher on Monday after President Donald Trump offered investors hope that an end to the war against Iran is drawing near.

    The 30-stock index added 415 points, or 0.9%. The S&P 500 rose 0.5%, while the Nasdaq Composite climbed 0.3%.

    “The United States of America is in serious discussions with A NEW, AND MORE REASONABLE, REGIME to end our Military Operations in Iran,” Trump said in a post on Truth Social on Monday.

    However, while the president added that “great progress has been made,” he also said that if a peace deal is not reached “shortly” and the Strait of Hormuz is not “immediately” reopened, the U.S. will “conclude our lovely ‘stay’ in Iran by blowing up and completely obliterating all of their Electric Generating Plants, Oil Wells and Kharg Island (and possibly all desalinization plants!), which we have purposefully not yet ‘touched.’”

    This comes after Trump said Sunday that Tehran had accepted most of the U.S.’ 15-point plan to end the war and that Iran has agreed to allow an additional 20 oil ships cross the Strait.

    “We still have this mindset that this is transitory, that somehow, yes, there’s going to be a short-term effect, but we should look through it,” Mohamed El-Erian, Allianz chief economic advisor, said on CNBC’s “Squawk Box” about sentiment in the equity market, adding that investors also aren’t pricing in “very limited policy flexibility” due to the war.

    “There’s a real question mark as to what the Fed is going to do, and we’re already running a 6% deficit,” El-Erian said. “The market hasn’t quite realized that if this goes on, the policy offsets much less than what we’ve had before.”

    Crude prices rose to start the week. Brent crude futures were marginally higher to above $112 per barrel. West Texas Intermediate futures were up 2% at above $102 a barrel.

    Traders have worried in recent weeks that higher energy prices could hurt the economy. El-Erian believes the next tipping point economically speaking would be “physical shortages,” saying Monday that “if we start seeing that in Asia, that will impact the U.S.” He continued, “the U.S. will now import higher products in terms of prices, and the question is do we now see also a disruption in the availability of products?”

    Wall Street is coming off a losing week, with the Dow and Nasdaq tipping into correction territory. The Dow, Nasdaq and S&P 500 all posted their fifth straight weekly declines.

    The market will be closed on Friday in observance of Good Friday, although the March jobs report is still scheduled for release that morning.

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  • Drivers to learn details of compensation scheme for mis-sold car finance – live updates

    Drivers to learn details of compensation scheme for mis-sold car finance – live updates

    What is motor finance?published at 15:23 BST

    Image source, Getty Images

    The vast majority of new cars, and many second-hand ones, are bought with finance agreements.

    About two million are sold this way each year, with customers paying an initial deposit, then a monthly fee with interest for the vehicle.

    The car loan scandal payouts row being addressed in our coverage today comes after the City regulator, the Financial Conduct Authority (FCA), banned deals in which the dealer received a commission from the lender, based on the interest rate charged to the customer.

    These were known as discretionary commission arrangements (DCAs).

    The FCA said this provided an incentive for a buyer to be charged a higher-than-necessary interest rate, leaving them paying too much.

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  • AudioCodes Announces Filing of Form 20-F for the Fiscal Year Ended December 31, 2025

    AudioCodes Announces Filing of Form 20-F for the Fiscal Year Ended December 31, 2025

    OR YEHUDA, Israel, March 30, 2026 /PRNewswire/ —

    Details

    AudioCodes Ltd. (NASDAQ: AUDC), a global leader in enterprise voice and VoiceAI business solutions (“AudioCodes”), today announced that it has filed its Annual Report on Form 20-F, including its audited financial statements, for the fiscal year ended December 31, 2025 (the “2025 Annual Report”) with the United States Securities and Exchange Commission. The 2025 Annual Report can be accessed on AudioCodes’ website at http://www.audiocodes.com (under the heading “Investor Relations“). Alternatively, AudioCodes’ shareholders may also request a hard copy of the 2025 Annual Report, free of charge, by contacting AudioCodes using the contact details provided at the top of this press release.

    Follow AudioCodes’ social media channels:

    AudioCodes invites you to join our online community and follow us on: AudioCodes Voice Blog, LinkedIn, X, Facebook, and YouTube.

    About AudioCodes

    AudioCodes Ltd. (NASDAQ: AUDC) (TASE: AUDC) is a global leader in enterprise voice and VoiceAI business solutions. We help organizations unlock the full value of voice, transforming every conversation, whether human or AI, into a strategic asset that drives better business outcomes. Our portfolio spans voice connectivity, unified communications and contact center integration, and next-generation voice AI applications that enhance collaboration, automate workflows and deliver real-time insights. With over 30 years of global experience and trusted by 65 of the Fortune 100, AudioCodes powers the intelligent enterprise, connecting people, platforms and data to move business forward.

    For more information on AudioCodes, visit http://www.audiocodes.com.

    ©2026 AudioCodes Ltd. All rights reserved. AudioCodes, AC, HD VoIP, HD VoIP Sounds Better, IPmedia, Mediant, MediaPack, What’s Inside Matters, OSN, SmartTAP, User Management Pack, VMAS, VoIPerfect, VoIPerfectHD, Your Gateway To VoIP, 3GX, AudioCodes One Voice, AudioCodes Meeting Insights, and AudioCodes Room Experience are trademarks or registered trademarks of AudioCodes Limited. All other products or trademarks are property of their respective owners. Product specifications are subject to change without notice.

    Logo – https://mma.prnewswire.com/media/2391462/4658414/audiocodes_Logo.jpg

    Company Contacts

    Niran Baruch,
    Chief Financial Officer
    AudioCodes
    Tel: +972-3-976-4000
    [email protected] 

    Roger L. Chuchen
    VP, Investor Relations
    AudioCodes
    Tel: 732-764-2552
    [email protected] 

    SOURCE AudioCodes

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  • Wabtec Announces First Quarter 2026 Earnings Release Date

    Wabtec Announces First Quarter 2026 Earnings Release Date

    Transportation solutions that revolutionize the way the world moves

    At Wabtec, we help our customers overcome their toughest challenges by delivering rail and industrial solutions that improve safety, efficiency and productivity.

    Wabtec Corporation

    30 Isabella Street
    Pittsburgh, PA 15212 – USA
    Phone: 412-825-1000
    Fax: 412-825-1019

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  • Texas Corporate Developments: What Officers and Directors Need to Know – The Harvard Law School Forum on Corporate Governance

    1. Texas Corporate Developments: What Officers and Directors Need to Know  The Harvard Law School Forum on Corporate Governance
    2. Legislators, business leaders highlight Texas policies driving competition with Wall Street  News From The States
    3. Dallas is positioning itself as the next Wall Street, bringing new opportunities for SMU students  smudailycampus.com
    4. Forget Delaware. Here’s why companies like Exxon want to incorporate in Texas now. | Opinion  Houston Chronicle

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