Category: 8. Health

The ongoing DETECT AS trial (NCT05230225) is a randomized investigation evaluating how electronic provider notification might impact the care of patients with severe aortic stenosis and their providers’ utilization of aortic valve replacement (AVR). Varsha Tanguturi, MD, MPH, cardiologist at Mass General Hospital and DETECT AS investigator, presented new data from the study at the ASPC 2025 Congress on CVD Prevention, in the poster, “The Impact of Electronic Provider Notification on Treatment of Severe Aortic Stenosis Amongst Different Provider Specialties: Findings from the DETECT AS Trial.”

In this conversation, she highlights how the findings she and her colleagues saw indicate almost universal increases in rates of AVR, across both provider and patient groups, with one of the most notable findings being the impact on women with aortic stenosis.

“We were hopeful that our intervention would make a difference,” she says. “That’s what we all want to do is make care better, but the size of the impact on women was actually quite impressive.”

This transcript has been lightly edited for clarity; captions were auto-generated.

Transcript

Why is aortic stenosis an important area of investigation in preventive cardiology?

I’ll back up a little bit. Early on in my fellowship in cardiology, I met a patient who was so sick from his aortic stenosis that he was having all sorts of near death experiences and arrhythmias, but then also kept getting turned down for procedures and to have his valve fixed. It got me thinking: what makes somebody so sick or what makes somebody really fall through the cracks like that for this disease? We really wanted to work upstream to figure out how to make this better, so that all the patients can get better care for their valvular disease. What we wondered about is, if we could tell providers about their patients’ aortic stenosis on echocardiography, if that would help them treat it more often. What we did was randomize providers to either receive a notification or just sort of standard of care and then look to see what the impact was on their treatment rates for aortic stenosis.

How was the notification system integrated into the clinical workflows?

We identified patients with severe aortic stenosis on their echocardiograms and then used this to identify the patients as well as the providers they were associated with. What we did was send an email, as well as an in-basket message, that detailed the fact that their patient had severe aortic stenosis, but then also some guideline-based suggestions for what they could do next that might have included further diagnostics, as well as recommendations for either evaluation or treatment by advanced or interventional providers to help treat the disease.

What are key findings you would like to highlight from the DETECT AS trial?

The thing we were most impressed with was that the notification seemed to make rates of aortic valve replacement higher, really, across the board, so across provider groups—meaning specialty types—as well as across patients. It was pretty impressive to see that the most notable impact was actually on women. There was a pretty impressive disparity in the usual care arm between men and women in their treatment rates, and then with notification, that disparity nearly melted away. When we look at providers, about 50% of the group was cardiologists, but about 50% of the group was also either primary care doctors or other specialists, non–cardiology-based physicians, and in both of those groups, there was a notable improvement in AVR rates.

Were there any surprising results?

I think that gender disparity actually really surprised us. We were hopeful that our intervention would make a difference. That’s what we all want to do is make care better, but the size of the impact on women was actually quite impressive.

It’s not entirely clear why. There’s many hypotheses. There’s some things about women’s hearts that might make them more prone to certain types of aortic stenosis that are, frankly, just a little more complicated and harder to pick up, like that, and so that might make it harder to identify on an echocardiogram by someone who’s looking quickly. It might be that the symptoms are vague or maybe minimized by patients in different ways, for different reasons, but really we don’t know for sure.

Constipation isn’t anyone’s ideal state of digestive affairs. The bloating, distension and overall discomfort of a gastrointestinal slowdown are a combo you’d probably prefer to skip. But for most of us, being backed up is an occasional fact of life (sometimes even a chronic one). Constipation is so common, in fact, that about 16% of U.S. adults say it’s a problem.

Fortunately, certain dietary supplements can help get things moving again. Though they may not work immediately, with a little patience, the right choices may make you feel lighter and brighter sooner than later. We tapped Sandhya Shukla, M.D., a board-certified gastroenterologist with Atlantic Coast Gastroenterology, a division of Allied Digestive Health, for her top supplement recommendations for constipation. She says the following five are worth a try.

1. Psyllium Husk

With its surging popularity on social media, psyllium husk may seem like a buzzy modern supplement. But it’s been used in Ayurvedic medicine as a natural remedy for constipation for thousands of years. What makes it so effective? Psyllium husk is rich in soluble fiber, which creates a slick, gel-like substance in the digestive tract that retains water. This, in turn, makes your poops easier to pass, Shukla says.

Besides psyllium’s ability to hold water, research reveals that it may also get things going by positively impacting gut microbiota. Those are the trillions of bacteria that regulate a healthy digestive tract. For instance, one small study found that supplementing with psyllium husk for four weeks led to beneficial changes in the gut microbiota of people with constipation. And another older study reported similar improvements in as little as one week.

Just note that psyllium husk can cause side effects in some people. (Shukla says a feeling of bloating is especially common.) You may want to start with a small dose to test your tolerance gradually. Also good to know: while supplements containing insoluble fiber may claim to ease constipation, they can actually make things worse. So, stick with soluble fiber-containing psyllium instead.

2. Probiotics

By now, you’ve probably heard of probiotics. These beneficial, live bacteria may be an inexpensive, over-the-counter means of maintaining a happy gut. Here’s a tip, though: don’t just choose any old strain you see. Current research shows that certain probiotic strains may be more helpful than others for specific health issues, including constipation.

One that has a solid track record is Lactobacillus reuteri. It works by getting your gut moving, helping you go more often., So, look for this strain specifically, or ask your doctor if another strain might be right for you.

3. Magnesium Oxide

Magnesium is often touted as a constipation preventer. However, with so many forms of this mineral on supplement shelves, it can be hard to distinguish which one is best. Shukla recommends magnesium oxide. Like psyllium husk, she says magnesium oxide draws more water into the stool, keeping things nice and soft to help with easier evacuation.

This form of magnesium may be particularly useful for treating chronic constipation that doesn’t have a known cause (also known as idiopathic constipation). In fact, the American Gastroenterological Association and American College of Gastroenterology recently released new guidelines recommending magnesium oxide as a pharmacological treatment for idiopathic constipation. But don’t be put off by the “pharmacological” terminology—magnesium oxide is available over the counter.  

Shukla says you can find magnesium oxide in different strengths. “I usually recommend starting at 200 or 250 milligrams [per day] and increasing to a maximum of 1,000 milligrams per day.” She also notes that people with decreased kidney function should avoid taking magnesium, as it can build to dangerous levels if the kidneys are unable to filter it properly.

4. Polyethylene Glycol

Never heard of polyethylene glycol? You may have seen it in dietary supplements without realizing it’s there. This compound is the active ingredient in powdered supplements like MiraLax and its generic equivalents.

Shukla recommends polyethylene glycol for its ease of use and effectiveness in alleviating constipation. “It is tasteless and odorless and therefore well tolerated,” she says. “Its absorption from the gut is negligible, making it a safe and effective option for treating constipation.” And unlike over-the-counter laxatives that should only be used occasionally, it’s safe for longer-term use. For instance, one study found that polyethylene glycol was safe and effective in reducing the frequency of hard or lumpy stools in people with chronic idiopathic constipation over the course of 24 weeks.

5. Prunes & Prune Juice

Turns out, Grandma was onto something. While not a supplement per se, the old prune juice remedy really is a smart move for getting regular again. And there’s research to prove it. For instance, one study found that people with chronic constipation who drank slightly less than 2 ounces of prune juice daily for eight weeks experienced significantly fewer hard or lumpy stools. That makes it food as medicine for the win!

“Prunes have high dietary fiber and sorbitol, both helpful for treating constipation,” explains Shukla. “This contributes to increased stool bulk and improved bowel movements.” Just ¼ cup of prunes (about 5 prunes) provides 3 grams of fiber.  Sorbitol, on the other hand, is a naturally occurring sugar alcohol that offers some surprising benefits for digestive health. “Sorbitol has osmotic properties that draw water into the intestines, keeping stool soft and easy to expel,” says Shukla. In fact, some people with quick intestinal transit actually avoid sorbitol for this reason. So, if you want to give prunes or prune juice a try, start slowly.

Our Expert Take

When your digestive tract gets a bit sluggish, a healthy diet, proper hydration and exercise should be your first lines of defense. When they aren’t enough, the supplement aisle has safe, effective options for constipation relief. Psyllium husk, probiotics, magnesium oxide and polyethylene glycol are all gastroenterologist-approved supplements for constipation relief. And if you’d prefer a more natural remedy, give prunes or prune juice a try. They may not be trendy, but they work!

Stroke is the fifth leading cause of death in the United States—and up to 80% of cases may be preventable through lifestyle changes. One of the most impactful steps you can take to reduce your risk is limiting sodium intake, since a high-sodium diet is strongly linked to high blood pressure, the leading cause of stroke., “The key point is stroke prevention is largely within our control through dietary and lifestyle choices, with sodium reduction being one of the most impactful single changes we can make,” says Aaron Feingold, MD, a cardiologist

Most people consume far more salt than is recommended—often without even realizing it. It’s not just about using the salt shaker too generously. Instead, the majority of sodium in the diet comes from highly processed foods, which are often loaded with it. By cutting back on salt, you may be able to lower your stroke risk. So, we asked doctors and dietitians what you can do to lower your sodium intake and why it’s so important.

Why a High-Sodium Diet is the #1 Thing to Avoid to Reduce Stroke Risk

“High sodium diets can exacerbate high blood pressure and aggravate preexisting risk factors, which increase the likelihood of developing a stroke over time,” says Leonard Pianko, MD, a cardiologist. “By reducing your sodium intake, you can lower your blood pressure and decrease your risk of a stroke.”

When you consume too much sodium, your body retains water, which increases blood volume. That extra fluid puts more pressure on your blood vessels, causing damage over time. It also forces your heart to work harder. “When the demand on our heart and blood vessels continues over a long period of time, we develop a high risk of experiencing a hemorrhagic or ischemic stroke,” says Feingold. “In a hemorrhagic stroke, our arterial walls rupture. In an ischemic stroke, we suffer a blockage.” 

Considering most individuals consume well over the recommended sodium limit of 2,300 mg per day, it’s wise to pay attention to how much you’re eating. To reduce your sodium intake, the experts we spoke with recommend some simple tips and swaps, including:

• Read Food Labels. Choose products with less than 5% of the Daily Value of sodium per serving.
• Cook at Home. Preparing your own meals keeps you in control of your sodium intake, unlike sodium-rich meals served at restaurants.
• Use Sodium-Free Flavor Enhancers. Experiment with different herbs and spices to flavor your meals without any extra salt. Be careful with sauces and condiments, which can also be high in salt.
• Buy Fresh or Frozen Vegetables. Canned varieties tend to contain the most sodium. Opting for fresh or frozen vegetables can keep sodium intake at bay.
• Limit Ultra-Processed Foods. Pre-packaged foods contain more sodium to enhance flavor and to preserve it. Examples of high sodium foods include processed meats, frozen pizzas, canned soups, breads and chips.

What To Do Instead to Reduce Stroke Risk

Limiting sodium in your diet is an important step in lowering your risk of stroke, but there are plenty of other things you can do as well. Here are some lifestyle changes that experts recommend. 

Try The DASH Diet Or The Mediterranean Diet

The DASH diet (Dietary Approaches to Stop Hypertension) has been shown to improve blood pressure and may lower risk of stroke. This diet consists of foods like fruits, vegetables, whole grains, legumes, low-fat dairy, nuts and healthy fats, while limiting highly processed foods that contain excessive sodium, sugar and saturated fat. 

Meanwhile, the Mediterranean diet, which emphasizes similar foods like fruits, vegetables, whole grains, legumes and fish, has been found to reduce the risk of stroke and other forms of heart disease. “A big part of that benefit comes from nutrients like potassium, fiber, and unsaturated fats, all of which help support healthy blood pressure,” says Deena Goldman, RDN.

Prioritize Healthy Fats

“Diets higher in unsaturated fats, specifically monounsaturated fats from olive oil and polyunsaturated fats from fatty fish, nuts and seeds, have been linked to lower risk of stroke,” Goldman says. “These fats help improve blood vessel function and reduce inflammation, both of which are key for keeping your heart healthy.”

Although research on saturated fat and stroke risk is mixed, incorporating more unsaturated fats into your diet is a heart-healthy choice that may help lower your risk.

Limit Your Alcohol Intake

Excess alcohol consumption can contribute to high blood pressure, Pianko points out. In one study, both moderate and high alcohol intake—defined as more than seven drinks per week—were associated with a significantly higher risk of stroke. The Dietary Guidelines for Americans recommends drinking no more than two alcoholic drinks per day for men and one for women.

Move Your Body

Regular physical activity is one of the best things you can do to lower your stroke risk. It helps to reduce blood pressure, eases strain on the heart and supports a healthy body weight—all key factors in stroke prevention. Along with this, limiting sedentary time is just as important. 

The American Heart Association recommends getting at least 150 minutes per week of moderate-intensity exercise or 75 minutes of vigorous exercise. If you’re new to exercise, just start moving—even a short walk is better than nothing. 

Maintain a Healthy Weight

Research suggests that a higher body mass index—particularly among those with overweight or obesity—may increase the risk of stroke. However, there is ongoing debate about how weight itself contributes to that risk. One study found that individuals with metabolically healthy obesity did not have an increased risk of stroke. Rather, it appears that metabolic effects commonly associated with obesity—such as high blood pressure and type 2 diabetes—increases risk. Therefore, prioritizing healthy behaviors that support metabolic health, independent of weight loss, may be the most important factor for reducing stroke risk.

Our Expert Take

To lower your risk of stroke, it’s important to avoid a high-sodium diet since it can raise your blood pressure, a major risk factor of stroke. To cut back, carefully read food labels, cook more meals at home, limit ultra-processed foods and experiment with fresh herbs and spices to boost flavor instead of relying on salt. Experts also encourage other lifestyle changes—such as following the DASH diet, limiting alcohol, and staying active—to further support heart and brain health.

New York, Aug. 02, 2025 (GLOBE NEWSWIRE) —

For decades, doctors claimed that cartilage couldn’t heal itself. But recent studies—led in part by Dr. Constance Chu of Stanford University—are challenging that belief. Using MRI imaging, researchers have observed signs of natural knee joint regeneration, inspiring new approaches to non-invasive recovery. One such approach, featured in the Feel Good Knees system, is gaining traction among active adults and seniors looking to avoid surgery and reclaim pain-free movement. This 5-minute “Knee Self-Restoration Ritual” is now being hailed as a gentle, science-guided method for unlocking the body’s hidden healing potential.

To see how this gentle routine is changing the way knee health is approached, visit the official Feel Good Knees Self-Healing System resource page.

Why Interest in “Knee Self-Healing” Is Surging in 2025

In 2025, more adults than ever are rethinking how they approach knee pain. A combination of rising surgery costs, drug-related risks, and breakthrough science is fueling public demand for safer, simpler alternatives that focus on the body’s natural ability to heal.

Searches for terms like “natural knee pain relief,” “cartilage regeneration,” and “avoid knee surgery” have exploded on Google, while platforms like Reddit, TikTok, and YouTube are flooded with user-driven discussions around joint health, body alignment, and pain-free movement at any age.

Why the sudden shift?

For starters, many are becoming disillusioned with traditional solutions. NSAIDs—commonly used anti-inflammatory medications—are now under increasing scrutiny. According to the American Journal of Medicine, NSAIDs are linked to over 16,500 deaths each year from gastrointestinal bleeding, while countless others suffer from liver and kidney complications caused by prolonged use【Source: AJM; Singh 1998】.

Surgical options aren’t much better. The average knee replacement surgery in the U.S. costs between $30,000 and $50,000, and can leave patients with long recoveries, visible scarring, and recurring discomfort【Source: Healthline; “What You Need to Know About Knee Surgery”】. And according to research published in Harvard Health, knee replacement implants often need to be replaced again after 10–15 years, creating additional surgeries and financial burdens down the line【Source: Harvard Health Publishing, 2023】.

But perhaps the most exciting reason for this surge in interest is emerging from the scientific community itself.

In a pivotal two-year study published in the Journal of the American Medical Association, researchers tracked 325 patients with knee cartilage degeneration. Using high-resolution MRI technology, they discovered that 37% of patients showed signs of cartilage healing—an outcome previously believed to be impossible. Their conclusion: “MRI results showed cartilage repair and healing.”【Source: JAMA, 2023】

This finding was further echoed by Dr. Constance Chu, a renowned Stanford Orthopedic Surgeon and Professor, who has led research showing that articular cartilage possesses self-repair capacity under the right mechanical and biological conditions. Her stance directly contradicts decades of conventional wisdom that once damage occurs, it’s permanent【Source: Stanford Medicine; Dr. Constance Chu Lab】.

These data points, combined with mounting anecdotal success stories, have created a groundswell. People no longer want to merely “manage” knee pain—they want to overcome it. And they’re now open to exploring simple, non-invasive rituals that support their body’s innate healing abilities.

In short, the concept of “knee self-healing” is no longer pseudoscience—it’s a growing global movement, grounded in evidence, and propelled by everyday people who are ready to reclaim their mobility.

Experience the difference a natural approach makes—explore the Feel Good Knees Self-Healing System now.

Feel Good Knees as a Response to This Shift

As millions seek non-invasive alternatives to injections and joint surgeries, one system is quietly leading the conversation: Feel Good Knees.

This 5-minute-per-day method, known as the “Knee Self-Restoration Ritual,” is designed to work with the body’s natural recovery systems—without pills, painful physical therapy, or medical equipment. At the center of this approach is a simple question: what if the knees were never the problem, but rather the neglected victim of poor alignment, restricted mobility, and years of muscle imbalance?

The Feel Good Knees system approaches joint discomfort not as a chronic curse, but as a correctable pattern—one that can be addressed with gentle, science-backed movement protocols.

Developed by fitness educator and medical manual therapy specialist Todd Kuslikis, the program is built for aging adults who want to reclaim control of their mobility from the comfort of home. The system blends therapeutic isometric holds, alignment adjustments, and relaxation-based techniques designed specifically for sore, stiff, or post-surgical knees. No gym memberships. No risky devices. Just five minutes a day in a chair, on the bed, or even while standing.

And its design wasn’t random. Kuslikis created the program after watching his own wife suffer through knee pain so severe that it interrupted their daily lives—and even their intimacy. Armed with a background in kinesiology, calisthenics, and injury rehabilitation, he began assembling a toolkit of gentle, proven movements that support circulation, lubrication, and functional knee positioning.

The result: a user-friendly program that doesn’t require athleticism, prior experience, or even full mobility to get started.

What makes it resonate so deeply with users is its simplicity. It doesn’t promise to “cure” anyone, nor does it rely on trends or gimmicks. Instead, Feel Good Knees positions itself as a natural response to a broken system—offering hope not through hype, but through self-guided action.

In a market flooded with braces, pills, and quick fixes, Feel Good Knees stands out for its ability to restore not just mobility, but also confidence. It acknowledges the science of self-healing, incorporates modern orthopedic findings, and translates them into a ritual that real people can actually use.

Ready to take control of your knee health?See how others are doing it with the Feel Good Knees program.

What Online Users Are Saying About This Category

Across the internet in 2025, a growing wave of users is challenging the mainstream narrative about joint pain—especially when it comes to aging knees.

From Reddit threads and podcast transcripts to YouTube commentary and TikTok explainers, people of all ages are increasingly skeptical of the traditional “pill or surgery” approach. What once felt like the default medical advice—NSAIDs, injections, or full joint replacements—is now facing resistance from everyday users who are openly sharing their frustrations and exploring non-invasive alternatives.

On TikTok, videos tagged with #kneepainrelief, #naturalhealing, and #jointmobility now boast millions of views. Creators frequently talk about lifestyle upgrades, posture corrections, and overlooked alignment techniques that have helped them avoid surgery. Others share their experiments with mobility routines, barefoot training, or low-impact movement regimens—all seeking the same goal: pain-free movement without dependency.

Meanwhile, popular podcasts in the health and aging space are dedicating entire episodes to mobility without medication, often highlighting overlooked therapies like isometric protocols, fascia release, and micro-adjustment exercises. Listeners are responding with enthusiasm, echoing sentiments like “why didn’t I hear about this 10 years ago?” and “my doctor never told me there were alternatives.”

In online review forums and comment sections, one theme is consistent: people want options that are gentle, proven, and accessible from home. There’s a growing cultural belief that knees—like skin, muscles, and other tissues—shouldn’t be excluded from the body’s natural healing intelligence.

The Feel Good Knees Self-Healing System has entered that conversation as a quiet frontrunner. While many systems rely on trends or unproven supplements, this method resonates because it taps into what online users already believe: that less can be more, and that a structured, low-resistance approach might actually work better than anything they’ve tried before.

For many, it’s not about avoiding doctors—it’s about finally finding something that aligns with their values and actually fits into their daily lives.

As one long-time wellness forum user put it, “After all the braces, pills, and pricey gadgets, I can’t believe a five-minute technique from a recliner is what finally gave me relief.”

Learn why thousands are turning to this self-healing method—access the Feel Good Knees official guide.

Who Might Gravitate Toward This Product in 2025

In 2025, the desire for pain-free movement isn’t limited to athletes or injury recovery patients. It spans a much wider audience—people who are tired of feeling sidelined by discomfort and eager to regain control of their bodies, starting with their knees.

The Feel Good Knees system was designed with these people in mind.

Many are active adults in their 50s, 60s, or 70s who feel youthful at heart, but find their knees limiting their participation in everyday joys—whether it’s gardening, golf, or chasing grandkids. These individuals aren’t necessarily seeking high-performance results. What they want is freedom: the ability to move confidently, bend easily, and wake up without that familiar throb in their joints.

Others include people who’ve had surgeries—some successfully, others not—who are looking for a way to support long-term joint health without relying on repeat procedures, follow-up injections, or prescription painkillers.

Then there are those who’ve been proactive all along. Health-conscious individuals who believe in prevention and mobility longevity. For them, the Feel Good Knees ritual acts as a daily tune-up—gentle, grounded in physiology, and supportive of natural function.

Even younger users, such as former athletes or those recovering from old sports injuries, are turning to this kind of program. Many are discovering that restoring patella alignment, relaxing overworked ligaments, and building low-impact joint strength can provide long-term comfort and stability—especially when done consistently over time.

What unites them all is the mindset: people who aren’t waiting around for pain to get worse. They want something simple, structured, and sustainable—without aggressive treatments or synthetic drugs.

Whether you’re just beginning to notice stiffness or have been managing knee discomfort for years, the Feel Good Knees system offers a calm, intelligent response to a complex problem. It doesn’t demand hours of your time or access to a clinic. Instead, it gives you the tools to take charge of your recovery right from your recliner.

To find out how this at-home system is helping thousands of people step back into life with strength and ease, explore the official Feel Good Knees Self-Healing System today.

Market Category Reflections – Why This Niche Is Expanding

The market for non-invasive pain management, particularly in the realm of joint support, has evolved rapidly in recent years. In 2025, a growing number of consumers are opting out of conventional solutions and exploring alternatives that were once considered fringe—such as fascia manipulation, isometric therapy, or passive alignment-based rituals.

One of the fastest-growing subcategories within this movement is the self-guided, home-based mobility program. Products like Feel Good Knees are thriving not just because they’re easier or less expensive—but because they’re aligned with a deeper cultural shift.

Today’s consumers are more informed than ever. They question the idea that aging automatically leads to immobility. They research. They cross-reference clinical studies. They ask if surgery is truly the only option. And most importantly, they’re demanding solutions that don’t require them to surrender control of their bodies—or their wallets.

This shift is reflected in keyword trends as well. Search volume for phrases like “natural knee cartilage support,” “home knee therapy,” and “knee healing without surgery” has surged globally. Influencers and wellness practitioners are also fueling the conversation, contributing to what many now recognize as a full-scale category breakout.

Part of this explosion in interest is due to the new wave of research validating the self-healing potential of joints. The 2023 JAMA study documenting 37% cartilage improvement in knees using natural, non-surgical methods has become a landmark reference point in online forums and health communities【Source: JAMA, 2023】.

Additionally, Stanford University orthopedic professor Dr. Constance Chu continues to make headlines for her bold position that “articular cartilage can heal” under proper conditions【Source: Stanford Medicine, 2023】. This single phrase, echoed across academic publications and interviews, has helped legitimize an entire category of non-invasive knee recovery methods that once existed outside the medical mainstream.

But it’s not just science driving the shift—it’s demographics.

The number of Americans over 60 continues to climb, and with it, a growing demand for mobility solutions that don’t rely on narcotics, joint injections, or surgical implants. As the healthcare system becomes more expensive and overburdened, programs that teach users to restore function naturally—on their own terms—are being embraced as both a medical necessity and a personal empowerment tool.

Feel Good Knees sits squarely in the center of that trend.

It reflects the new definition of wellness: individualized, sustainable, evidence-informed, and low-risk. It also speaks to a larger consumer truth—people no longer want to be patients. They want to be participants in their own recovery.

Take the first step toward pain-free knees—visit the Feel Good Knees Self-Healing System homepage.

Public Debate – Supporters, Skeptics, and the Signals Behind the Buzz

As interest in natural joint healing grows, so too does the conversation surrounding its legitimacy. The Feel Good Knees Self-Healing System has found itself at the center of this expanding debate—welcomed by many, questioned by others, and observed closely by professionals across fields ranging from physical therapy to biohacking.

Supporters of the system point to the growing body of research that validates the potential for cartilage regeneration and biomechanical realignment, even in aging populations. They highlight studies like the 2023 publication in The Journal of the American Medical Association, which showed measurable MRI-documented cartilage improvements in over one-third of participants using non-surgical interventions【Source: JAMA, 2023】. They also cite expert commentary from Stanford Orthopedic Professor Dr. Constance Chu, whose work continues to affirm that knee cartilage may not be as static and unchangeable as once believed【Source: Stanford Medicine】.

Beyond the academic world, practitioners in manual therapy and movement science have voiced support as well. They see routines like Feel Good Knees not as miracle cures, but as structured interventions that restore healthy joint mechanics through cumulative, low-impact input. In this light, the system becomes a tool for long-term maintenance, rather than a quick-fix remedy.

However, not everyone is convinced.

Skeptics warn that some users may overestimate the results or delay needed medical intervention. Critics argue that while natural healing is promising, it must be personalized and carefully monitored—particularly for those with advanced osteoarthritis, surgical complications, or degenerative meniscus damage.

Others raise concerns about the oversimplification of knee biomechanics in popular marketing. They note that joint dysfunction is often multifactorial—impacted by weight, posture, injury history, and even genetics—and that no single solution, however well-designed, should be seen as universal.

But even in these critiques, there is common ground.

Most observers—supportive or skeptical—acknowledge that the system’s emphasis on low-risk, low-impact routines is a net positive. The real disagreement lies not in whether such programs should exist, but in how broadly they should be recommended.

What continues to tip the scale in the system’s favor is one undeniable factor: user experience.

With over 119,000 users and countless unsolicited testimonials reporting improved comfort, enhanced mobility, and a renewed sense of independence, the public momentum is difficult to ignore.

Even many cautious observers admit that if a program is affordable, easy to follow, and doesn’t interfere with conventional treatment, it may provide meaningful benefits—whether through physical stimulation or the psychological empowerment that comes with taking action.

And that may be the most important signal behind the buzz: people want to participate in their own recovery. Not just passively treat symptoms—but actively work toward a better outcome.

Uncover the breakthrough routine helping people move without pain—see what the Feel Good Knees System is all about.

About Feel Good Knees

Feel Good Knees is a mobility-focused wellness program designed to support healthy knees through natural, non-invasive methods. Founded by fitness educator and injury prevention specialist Todd Kuslikis, the brand’s core mission is to empower aging adults to regain control of their movement without surgery, pills, or high-intensity exercise.

Rooted in decades of anatomical study, therapeutic movement design, and orthopedic science, the system was developed specifically for seniors and adults dealing with recurring knee pain, stiffness, or joint instability. It combines gentle isometric protocols, alignment-based postural corrections, and fascia-releasing techniques—all structured into a simple, five-minute daily ritual.

What makes the Feel Good Knees approach unique is its intentional accessibility. It requires no special equipment, no athletic background, and no in-person appointments. The system is self-paced, easy to follow, and built to deliver meaningful results from the comfort of home.

The company operates on an education-first philosophy. Every technique is demonstrated via high-definition video and explained in plain language, ensuring users understand not just what to do—but why it works. This teaching-based model reflects the brand’s belief that real change happens when users are informed, not just instructed.

Feel Good Knees also incorporates the latest research into joint healing, muscle recruitment, and postural alignment. The program is updated as new science emerges, and remains committed to transparency, user safety, and long-term joint wellness.

Your knees deserve to feel better—discover the Feel Good Knees approach that’s changing lives.

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Final Disclaimer

This press release is for informational purposes only. The content herein does not constitute financial, legal, or medical advice. Feel Good Knees is not intended to diagnose, treat, predict, or guarantee any result or outcome. Individual experiences may vary, and outcomes are not assured.

Some links in this release may be promotional in nature and may lead to third-party websites. The publisher or author may receive compensation through affiliate commissions if a purchase is made through these links. This compensation does not affect the price you pay and helps support continued research and content publication.

All statements made about product features, platform strategies, or training content reflect publicly available information, user discussions, or historical trends, and are not endorsed or validated by regulatory bodies. Please perform your own research before making financial, technological, or purchasing decisions.

Misplaced memories and slowed recall often accompany aging, yet the brain’s molecular decline begins long before the first “senior moment.’”

A new study zeroes in on the cell’s protein assembly lines – where proteins are built, folded, and dispatched – revealing the earliest tremors of decline that future therapies may aim to stabilize.

The research shows that when those lines decelerate, neurons choke on unfinished products, triggering a cascade that ends with sticky protein clumps and fading cognition.

The study was led by Stanford biologist Judith Frydman, who has conducted extensive research tracking the life cycle of proteins from their genesis (birth) to their eventual breakdown and removal (grave). 

Brain aging slows protein production

Cells rely on proteostasis, the steady balance between making, folding, and recycling proteins, to keep their inner machinery humming. Each disruption saps energy and invites damage that accumulates over decades.

A critical step is translation elongation, the moment a ribosome adds one amino acid after another to a growing chain, and that step loses tempo with age according to large-scale profiling in worms, flies, and mice, a slowdown that now extends to vertebrate brains.

“Our new study begins to provide a mechanistic explanation for a phenomenon widely seen during aging, which is increased aggregation and dysfunction in the processes that make proteins,” said Frydman.

The team also noted that chaperones which normally police misfolded chains arrive late to stalled ribosomes, magnifying the risk that malformed proteins will stick together and poison nearby circuits.

Brain aging in killifish

The African turquoise killifish lives just four to six months in laboratory ponds, giving researchers a fast, almost time-lapse view of vertebrate aging without the budget burden of housing mice for years.

Adapted to puddles that vanish each dry season, the fish packs growth, reproduction, and decline into one academic semester, making experimental timelines feasible for doctoral students as well as grant cycles.

Its short lifespan does not mean simplicity. The killifish brain holds the full suite of vertebrate cell types, and its genome carries many of the same quality-control genes that humans use to police protein folding.

That compressed life course allowed the team to capture brains at three life stages and log shifts in metabolites, RNAs, and proteins without waiting years.

The researchers have produced one of the most detailed aging atlases yet assembled for a vertebrate.

Stalled ribosomes harm the brain

Ribosome profiling revealed a surge in stalling and head-on collisions on aging transcripts packed with lysine and arginine codons, transforming once-smooth molecular traffic into a shimmering gridlock.

Proteins that guard DNA and shuttle RNA, two classes dense in those basic amino acids, fell sharply in abundance even though their messenger RNA stayed stable. This points to a production glitch rather than a transcription problem.

Slowed traffic also left half-built chains exposed, boosting insoluble aggregates that are a signature of Alzheimer’s, Parkinson’s, and ALS. In the killifish, the aggregates appeared in brain areas tied to learning days before behavioral decline emerged.

The mismatch between transcripts and proteins, known as protein-transcript decoupling, now has a clockwork explanation rooted in translation speed – closing a puzzle that has bothered biologists for a decade.

Slow protein speed harms aging brain

When an assembly line halts, quality as well as quantity suffers because nascent chains misfold before cellular helpers can intervene, creating time bombs that only reveal themselves weeks or months later.

“Changes in the speed of ribosome movement along the mRNA can have a profound impact on protein homeostasis,” noted Jae Ho Lee, a professor at Stony Brook University.

The killifish data suggest that even a modest slowdown reshapes the proteome toward instability, opening gaps in genome maintenance, RNA splicing, and energy production that multiply across thousands of proteins.

Those gaps echo findings in post-mortem human cortex, where ribosomal subunits and DNA repair factors crumble first, hinting at a common aging script that crosses species and tissues.

Drugs may fix protein-making

Geroscience researchers are already testing drugs like rapamycin, which targets the cell’s protein-making machinery. It has been shown to extend lifespan in many mammals and is showing early promise in Alzheimer’s trials focused on safety and biomarkers.

Fine-tuning elongation specifically, rather than throttling global protein synthesis, could sidestep side effects like immunosuppression and poor wound healing.

Researchers are screening small molecules that help separate collided ribosomes or enhance rescue proteins like Pelota. Zebrafish, nematodes, and cell cultures are being used for fast, low-cost testing of drug responses.

If those tools keep elongation on tempo, they might starve neurodegenerative seeds before they sprout, moving the field beyond symptomatic relief toward true prevention and even extension of healthspan.

Questions still remain

Why basic proteins suffer first, and whether the same translation traffic jams appear in humans by midlife, remain open questions that high-resolution ribosome profiling in brain organoids could address.

The killifish study hints that neurons, already energy-hungry, might lack spare fuel to run sluggish assembly lines – a factor worth investigating.

The tiny fish offer a reminder that aging brains may struggle not from lack of effort, but from processes that slow down just slightly. Researchers can now measure these subtle delays – and may one day learn how to correct them.

The study is published in the journal Science.

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Liver cancer is the third leading cause of all cancer deaths worldwide, and the number of diagnoses is expected to nearly double by 2050. However, a new study suggests that upwards of 60% of those cases could be preventable, ultimately saving between 8 million and 15 million lives.

A growing, but reversible issue

The Lancet Commission on liver cancer released a study Monday suggesting that with increased vaccination rates and lifestyle changes, the death rate from liver cancer could be dramatically reversed.

Absent any changes in health policy, the number of liver cancer deaths is projected to reach 1.37 million in 2050, compared to 760,000 in 2022.

“There is an urgent need to raise awareness within society about the severity of the growing health issue of rising liver cancer cases,” Lancet Commission author Valérie Paradis said. “Compared with other cancers, liver cancer is very hard to treat but has more distinct risk factors, which help define specific prevention strategies.”

The global impact of liver cancer

In 2022, there were 870,000 cases of liver cancer, making it the sixth most common cancer worldwide. According to the Lancet Commission, that number is expected to hit 1.52 million cases by 2050. Those cases include cancers that result from hepatitis B and C infections, as well as alcohol- and obesity-related complications.

While the numbers of hepatitis B and C infections are expected to fall from 39% to 37% and 29% to 26% by 2050, respectively, alcohol- and obesity-related cancers are expected to increase from 19% to 21% and 8% to 11%. These numbers account for the total proportion of projected diagnoses between 2022 and 2050.

“Liver cancer is a growing health issue around the world,” said lead researcher Jian Zhou, a professor at Fudan University in China.

Zhou described liver cancer as “one of the most challenging cancers to treat,” adding, “We risk seeing close to a doubling of cases and deaths from liver cancer over the next quarter of a century without urgent action to reverse this trend.”

China accounts for the world’s largest liver cancer population, with roughly 367,657 new cases diagnosed in 2022. That number far outpaces the U.S., which ranks second with 43,492 new cases in 2022, and Japan’s 41,388 new cases, according to the World Cancer Research Fund.

Liver cancer in the U.S. is pretty uncommon, accounting for just 2.1% of new cancer cases to date, in 2025, according to the National Cancer Institute. Nevertheless, liver cancer precursors such as metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH) affect around 1 in 4 U.S. adults. Both of those diseases are associated with cirrhosis of the liver, a disorder most people correlate with heavy drinking.

“I think for most people, if you say cirrhosis, they immediately think of a relative, of someone who was a heavy drinker,” said Baylor College of Medicine’s Dr. Hashem El-Serah, a co-author of the report. “I think the vast majority do not make the tie between MASLD, or fatty liver, and cirrhosis and liver cancer.”

What can be done?

Liver cancer may be hard to treat, but researchers and doctors note it’s not difficult to prevent. They point to greater hepatitis vaccination rates, GLP-1s to treat obesity, universal screening for adults, increased alcohol taxes and warning labels, and more robust detection methods –– especially for those with liver disease –– as just a few of the ways policymakers could mitigate liver cancer rates.

“With joint and continuous efforts, we believe many liver cancer cases can be prevented, and both the survival and quality of patients with liver cancer will be considerably improved,” said Paradis.

Patients had improved outcomes after ST-elevation myocardial infarction (STEMI) and when living with coronary plaque when using glucagon-like peptide-1 (GLP-1) receptor agonists according to posters presented during the ASPC 2025 Congress on CVD Prevention, held in Boston from August 1 to August 3, 2025.^1,2 These results encourage the use of GLP-1s in this area, improving survival for patients living with these conditions.

GLP-1s have shown their use in type 2 diabetes primarily, capable of lowering the blood sugar of those who use the medication as prescribed.³ These medications have also shown use in treating obesity. Although there have been some studies that have shown potential benefit of using GLP-1s in cardiovascular disease, the extent of their benefit in patients with coronary plaque and in patients following acute ST-elevation myocardial infarction (STEMI) is unknown.

The effectiveness of GLP-1 therapy in patients with coronary plaque was the primary objective of a poster presented during the conference.¹ There were 2 propensity-matched cohorts with documented cases of coronary plaque who were identified using the TriNetX electronic medical record network between January 1, 2022, and December 31, 2024. The 2 groups corresponded to those who had received GLP-1s and those who had not. Patients were included if they had imaging that was consistent with plaque and had a diagnostic code for atherosclerosis.

Lipid panel, inpatient hospitalizations, hemoglobin A_1C levels, major adverse cardiovascular events, and myocardial infarction were all primary outcomes measured in the study.

Patients who used GLP-1s had a lower risk of major adverse cardiovascular events (34.3% vs 41.9%; OR, 0.725; 95% CI, 0.699-0.751), myocardial infarction (13.9% vs 20.8%; OR, 0.615; 95% CI, 0.586-0.644), and inpatient visits (22.8% vs 28.7%; OR, 0.731; 95% CI, 0.702-0.761) compared with those who had not used GLP-1s.

Those who had used GLP-1s had higher 1-year event-free survival and improved lipid profiles. Those who used GLP-1s had higher triglycerides but had more improvement in levels compared with those who did not use GLP-1s.

The researchers concluded that adverse cardiovascular outcomes were associated with the use of GLP-1s, including those in high-risk atherosclerotic populations.

GLP-1s are also beneficial when used in those with acute STEMI compared with not using the treatment.² The second study also used the TriNetX Research Network to collect cohort data collected between January 1, 2022, and December 31, 2024. All patients were separated into 2 groups, where 1 group had taken GLP-1s and the other had not. Major adverse cardiovascular events, myocardial infarction, lipid profile differences, and inpatient hospitalizations were all primary outcomes of this study.

Higher 1-year event-free survival was found in those who had received GLP-1s, and lipid panels showed lower LDL and total cholesterol. The GLP-1 group did have higher triglycerides compared with those who had not received GLP-1s. Glycemic control was improved in those who had been treated with GLP-1s.

Hospital readmission rates over 30 days were lower in those who had taken GLP-1s (9.3% vs 12.7%; OR, 0.70; 95% CI, 0.65-0.76). Major adverse cardiovascular events (57.2% vs 66.7%; OR, 0.668; 95% CI, 0.628-0.711), recurrent myocardial infarctions (41.2% vs 53.2%; OR, 0.617; 95% CI, 0.581-0.655), and inpatient admissions (31.7% vs 39.4%; OR, 0.716; 95% CI, 0.672-0.762) were all lower in those who had taken GLP-1s compared with those who had not.

The researchers concluded that GLP-1s were beneficial when used in those with acute STEMI, improving outcomes and survival in the cohort who had utilized the treatment. Across both studies, GLP-1 shows promise when used in those with cardiovascular conditions, demonstrating a new avenue of treatment that could have major implications on future treatment of these conditions.

References

1. Yousafzai O, Annie F, Rinehart S. GLP-1 receptor agonists and cardiovascular outcomes in patients with coronary outcomes in patients with coronary plaque: a real-world propensity-matched analysis. Presented at ASPC 2025 Congress on CVD Prevention; August 1-3, 2025; Boston, MA. Poster 211

2. Yousafzai O, Annie F, Rinehart S. GLP-1 receptor agonists and cardiovascular outcomes following STEMI: a propensity-matched cohort study. Presented at ASPC Congress on CVD Prevention; August 1-3, 2025; Boston, MA. Poster 271

3. GLP-1 agonists. Cleveland Clinic. Updated July 3, 2023. Accessed August 1, 2025. https://my.clevelandclinic.org/health/treatments/13901-glp-1-agonists